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Control charts in healthcare quality monitoring: a systematic review and bibliometric analysis. 医疗质量监控中的控制图:系统回顾与文献计量分析》。
IF 2.7 4区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-19 DOI: 10.1093/intqhc/mzae060
Muhammad Waqas, Song Hua Xu, Sajid Hussain, Muhammad Usman Aslam

Control charts, used in healthcare operations to monitor process stability and quality, are essential for ensuring patient safety and improving clinical outcomes. This comprehensive research study aims to provide a thorough understanding of the role of control charts in healthcare quality monitoring and future perspectives by utilizing a dual methodology approach involving a systematic review and a pioneering bibliometric analysis. A systematic review of 73 out of 223 articles was conducted, synthesizing existing literature (1995-2023) and revealing insights into key trends, methodological approaches, and emerging themes of control charts in healthcare. In parallel, a bibliometric analysis (1990-2023) on 184 articles gathered from Web of Science and Scopus was performed, quantitatively assessing the scholarly landscape encompassing control charts in healthcare. Among 25 countries, the USA is the foremost user of control charts, accounting for 33% of all applications, whereas among 14 health departments, epidemiology leads with 28% of applications. The practice of control charts in health monitoring has increased by more than one-third during the last 3 years. Globally, exponentially weighted moving average charts are the most popular, but interestingly the USA remained the top user of Shewhart charts. The study also uncovers a dynamic landscape in healthcare quality monitoring, with key contributors, research networks, research hotspot tendencies, and leading countries. Influential authors, such as J.C. Benneyan, W.H. Woodall, and M.A. Mohammed played a leading role in this field. In-countries networking, USA-UK leads the largest cluster, while other clusters include Denmark-Norway-Sweden, China-Singapore, and Canada-South Africa. From 1990 to 2023, healthcare monitoring evolved from studying efficiency to focusing on conditional monitoring and flowcharting, with human health, patient safety, and health surveys dominating 2011-2020, and recent years emphasizing epidemic control, COronaVIrus Disease of 2019 (COVID-19) statistical process control, hospitals, and human health monitoring using control charts. It identifies a transition from conventional to artificial intelligence approaches, with increasing contributions from machine learning and deep learning in the context of Industry 4.0. New researchers and journals are emerging, reshaping the academic context of control charts in healthcare. Our research reveals the evolving landscape of healthcare quality monitoring, surpassing traditional reviews. We uncover emerging trends, research gaps, and a transition in leadership from established contributors to newcomers amidst technological advancements. This study deepens the importance of control charts, offering insights for healthcare professionals, researchers, and policymakers to enhance healthcare quality. Future challenges and research directions are also provided.

背景 控制图用于医疗运营,以监控流程的稳定性和质量,对于确保患者安全和改善临床结果至关重要。这项综合研究旨在通过系统综述和开创性的文献计量学分析这两种方法,全面了解控制图在医疗质量监控中的作用和未来前景。材料与方法 对 223 篇文章中的 73 篇进行了系统综述,综合了现有文献(1995-2023 年),揭示了控制图在医疗保健中的主要趋势、方法论途径和新兴主题。与此同时,还对从 Web of Science 和 Scopus 收集到的 184 篇文章进行了文献计量分析(1990-2023 年),对医疗保健领域控制图的学术前景进行了定量评估。结果 在 25 个国家中,美国是控制图的主要使用者,占所有应用的 33%,而在 14 个卫生部门中,流行病学占 28%。在过去三年中,控制图在健康监测中的应用增加了三分之一以上。在全球范围内,指数加权移动平均(EWMA)图表最受欢迎,但有趣的是,美国仍然是使用 Shewhart 图表最多的国家。研究还揭示了医疗质量监测领域的动态格局,包括主要贡献者、研究网络、研究热点趋势和领先国家。J.C. Benneyan、W.H. Woodall 和 M.A. Mohammed 等具有影响力的作者在这一领域发挥了主导作用。在国家网络中,美国-英国是最大的集群,其他集群包括丹麦-挪威-瑞典、中国-新加坡和加拿大-南非。从 1990 年到 2023 年,医疗监测从研究效率发展到关注条件监测和流程图,2011-2020 年以人类健康、患者安全和健康调查为主,近几年强调流行病控制、COVID-19 SPC、医院和使用控制图的人类健康监测。它确定了从传统方法到人工智能(AI)方法的过渡,在工业 4.0 的背景下,机器学习(ML)和深度学习(DL)的贡献越来越大。新的研究人员和期刊不断涌现,重塑了医疗控制图的学术背景。讨论与结论 我们的研究揭示了医疗质量监控不断演变的格局,超越了传统的评论。我们发现了新的趋势、研究缺口,以及在技术进步的同时,领导层正从老牌贡献者向新人过渡。这项研究深化了控制图的重要性,为医疗专业人员、研究人员和政策制定者提供了提高医疗质量的见解。同时还提供了未来的挑战和研究方向。
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引用次数: 0
Measuring the overall development of patient safety in a new hospital using trigger tools. 使用触发工具衡量新医院患者安全的整体发展情况。
IF 2.7 4区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-19 DOI: 10.1093/intqhc/mzae064
Ivan Adamovic, Peter Dahlem, Johannes Brachmann

The new building of the Hospital in Lichtenfels (Germany) was put into operation in mid-July 2018. Neither the medical personnel nor medical departments have been changed. We want to evaluate how 'safe' or 'insecure' the new hospital or department in the beginning might have been. Our objective is to investigate if safety decreases at the beginning in a new hospital, despite modern environments and conditions. Adverse events (AEs) associated with treatment were included to evaluate the total number of AEs resulting from medical care and medications. Patients' records had to be closed and completed, the length of stay had to be at least 24 h, and the patient had to have been formally admitted to the hospital [Institute for Healthcare Improvement (IHI) 'Global Trigger Tool' (GTT) recommendation]. The identified AEs were grouped into 27 categories of the IHI 'GTT'. We randomly reviewed 40 patient records per month 6 months before and 6 months after moving to the new hospital. Statistical analysis showed that there was no significant difference in individual AEs. The sum of AEs was statistically higher after moving into a new hospital. A complete number of harms did reach statistical significance (χ2 = 6.62; df = 1; P < .05; Cramer's V = 0.12), indicating that new environments 'trigger' significantly more potential errors (50%) in comparison to the old environments (38.33%). According to our findings, the new hospital appears to be slightly insecure in the first 6 months after opening.

背景:德国利希滕费尔斯医院的新大楼于 2018 年 7 月中旬投入使用。医务人员和医疗部门均未发生变化。我们希望评估新医院或新科室在初期的 "安全 "或 "不安全 "程度。我们的目的是调查,尽管环境和条件都很现代化,但新医院在成立之初的安全性是否会降低:方法:纳入与治疗相关的不良事件,以评估医疗护理和药物导致的不良事件总数。患者的病历必须是完整的,住院时间至少为 24 小时,必须是正式入院(美国医疗保健改进研究所 IHI GTT "全球触发工具 "建议)。已确认的不良事件被归入医疗保健改进研究所 "全球触发工具 "的 27 个类别。我们每月随机审查 40 份患者病历,分别在搬到新医院前 6 个月和搬到新医院后 6 个月进行审查:统计分析显示,单个不良事件没有明显差异。迁入新医院后,不良事件的总和在统计学上较高。不良事件总数在统计学上具有显著性(χ2=6.62;df=1;p):根据我们的研究结果,新医院在成立后的第一阶段(6 个月)稍显不安全。
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引用次数: 0
Sharps injuries among healthcare workers in Liberia and Ghana: a cross-sectional survey. 利比里亚和加纳医护人员的利器伤害:横断面调查。
IF 2.7 4区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-19 DOI: 10.1093/intqhc/mzae066
Laura Jean Ridge, John Arko-Mensah, Josh Lambert, Lydia Aziato, G Clinton Zeantoe, Henry Duah, Marjorie McCullagh

There are little data on sharps injuries among healthcare workers in West Africa despite the region's high rate of hepatitis B and human immunodeficiency virus. The purpose of this study is to investigate healthcare workers' history of sharps injuries in Liberia and Ghana. An electronic cross-sectional survey was conducted among healthcare workers in Liberia and Ghana from February to June 2022. A link to the survey was texted to participants through professional association membership lists, including nursing, midwifery, and physician assistant organizations in both Liberia and Ghana and a physician organization in Ghana only. Five hundred and nine participants reported an average of 1.8 injuries per year in Liberia and 1.1 in Ghana (P ≤ .01); 15.1% of healthcare workers reported three or more injuries in the past year. Liberia had a higher proportion of frequently injured workers (P = .01). Frequently injured workers were evenly distributed across worker types. Workers in this region are vulnerable to sharps injuries. A frequently injured subset of workers likely has distinctive risk factors and would benefit from further investigation and intervention.

尽管西非地区的乙型肝炎和艾滋病毒感染率很高,但有关该地区医护人员被利器所伤的数据却很少。本研究旨在调查利比里亚和加纳医护人员的利器伤害史。2022 年 2 月至 6 月,我们对利比里亚和加纳的医护人员进行了一次电子横断面调查。调查链接通过专业协会会员名单发送给参与者,包括利比里亚和加纳的护理、助产和医生助理组织,以及加纳的一个医生组织。509 名参与者报告,在利比里亚平均每年发生 1.8 起伤害事故,在加纳平均每年发生 1.1 起伤害事故(p=0.05)。
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引用次数: 0
Use of the DMAIC Lean Six Sigma quality improvement framework to improve beta-lactam antibiotic adequacy in the critically ill. 使用 DMAIC 精益六西格玛质量改进框架,提高重症患者使用β-内酰胺类抗生素的充分性。
IF 2.7 4区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-19 DOI: 10.1093/intqhc/mzae062
Rebecca J Wessel, Christina G Rivera, Sara E Ausman, Nathaniel Martin, Shienna A Braga, Natalie T Hagy, Lindsay N Moreland-Head, Omar M Abu Saleh, Ognjen Gajic, Paul J Jannetto, Erin F Barreto

Beta-lactam antibiotics are widely used in the intensive care unit due to their favorable effectiveness and safety profiles. Beta-lactams given to patients with sepsis must be delivered as soon as possible after infection recognition (early), treat the suspected organism (appropriate), and be administered at a dose that eradicates the infection (adequate). Early and appropriate antibiotic delivery occurs in >90% of patients, but less than half of patients with sepsis achieve adequate antibiotic exposure. This project aimed to address this quality gap and improve beta-lactam adequacy using the Define, Measure, Analyze, Improve, and Control Lean Six Sigma quality improvement framework. A multidisciplinary steering committee was formed, which completed a stakeholder analysis to define the gap in practice. An Ishikawa cause and effect (Fishbone) diagram was used to identify the root causes and an impact/effort grid facilitated prioritization of interventions. An intervention that included bundled education with the use of therapeutic drug monitoring (TDM; i.e. drug-level testing) was projected to have the highest impact relative to the amount of effort and selected to address beta-lactam inadequacy in the critically ill. The education and TDM intervention were deployed through a Plan, Do, Study, Act cycle. In the 3 months after "go-live," 54 episodes of beta-lactam TDM occurred in 41 unique intensive care unit patients. The primary quality metric of beta-lactam adequacy was achieved in 94% of individuals after the intervention. Ninety-four percent of clinicians gauged the education provided as sufficient. The primary counterbalance of antimicrobial days of therapy, a core antimicrobial stewardship metric, was unchanged over time (favorable result; P = .73). Application of the Define, Measure, Analyze, Improve, and Control Lean Six Sigma quality improvement framework effectively improved beta-lactam adequacy in critically ill patients. The approach taken in this quality improvement project is widely generalizable to other drugs, drug classes, or settings to increase the adequacy of drug exposure.

背景:β-内酰胺类抗生素因其良好的有效性和安全性而被广泛应用于重症监护病房。脓毒症患者必须在确认感染后尽快(早期)使用β-内酰胺类抗生素,治疗可疑病原体(适当),并使用能根除感染的剂量(足量)。90%以上的患者都能得到早期和适当的抗生素治疗,但只有不到一半的脓毒症患者能得到充分的抗生素治疗。本项目旨在利用 DMAIC 精益六西格玛质量改进框架解决这一质量差距并提高β-内酰胺的充足性:方法:成立了一个多学科指导委员会,并完成了利益相关者分析,以确定实践中的差距。采用石川因果(鱼骨)图确定根本原因,并通过影响/努力网格确定干预措施的优先次序。据预测,一项包括教育与治疗药物监测(TDM,即药物水平检测)捆绑在一起的干预措施,相对于付出的努力而言影响最大,因此被选为解决重症患者β-内酰胺不足问题的干预措施:通过 "计划、实施、研究、行动"(PDSA)循环来部署教育和 TDM 干预措施。在 "启动 "后的三个月内,有 41 名重症监护病房患者接受了 54 次β-内酰胺类药物的 TDM 治疗。干预后,94% 的患者达到了β-内酰胺充足性这一主要质量指标。94%的临床医生认为所提供的教育是充分的。作为抗菌药物管理的核心指标,抗菌药物治疗天数的主要平衡指标随着时间的推移没有发生变化(结果良好;P=0.73):结论:应用 DMAIC 精益六西格玛质量改进框架有效提高了重症患者使用β-内酰胺类药物的充分性。该质量改进项目所采用的方法可广泛应用于其他药物、药物类别或环境,以提高药物暴露的充分性。
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引用次数: 0
Attitude toward perioperative safety among operation room clinicians at Ethiopian University Hospital. 埃塞俄比亚大学医院手术室临床医生对围手术期安全的态度。
IF 2.7 4区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-11 DOI: 10.1093/intqhc/mzae051
Yophtahe Woldegrima Berhe, Yonas Admasu Ferede, Biresaw Ayen, Tadesse Belayneh Melkie, Aklilu Yiheyis, Nurhusen Riskey Arefayne, Yosef Belay Bizuneh

Patient safety is a fundamental of good quality and also a high priority for the health-care system. Maintaining patient safety reduces errors and harm that patients can suffer during health care. The operating room clinicians have a vital role in ensuring patient safety. The general objective of this study was to assess attitudes towards perioperative safety and associated factors among the operation room clinicians at the University of Gondar Comprehensive Specialized Hospital (UoGCSH), Northwest Ethiopia, 2022. A cross-sectional study was conducted on operation room clinicians at UoGCSH. The data were collected by using a self-administered structured questionnaire that included the Safety Attitude Questionnaire (SAQ). Binary logistic regression analysis was employed, and the strength of association was described in adjusted odds ratios with a 95% confidence interval (CI). A total of 260 (76% response rate) operation room clinicians have participated in this study. The mean ± SD of attitude toward perioperative safety was 57.8 ± 0.9. Only 32 (12.3%) operation room clinicians have shown a favorable attitude toward perioperative safety. Most of the clinicians were found to have unfavorable attitudes toward all domains of SAQ except the stress recognition domain. Age >30 years [adjusted odds ratios (AOR): 3.1, CI: 1.1, 8.7, P = .035], working for ≥40 h/week (AOR: 3.9, CI: 1.4, 11.1, P = .01), working in ophthalmologic (AOR: 12.0, CI: 3.8, 38.8, P < .001) and gynecologic (AOR: 3.6, CI: 1.1, 12.7, P = .04) operation rooms, and having training on perioperative safety (AOR: 2.6, CI: 1.1, 6.5, P < .03) were found associated with having favorable attitude toward perioperative safety. Most operation room clinicians had an unfavorable attitude toward perioperative safety and all the domains of SAQ except the stress recognition domain. Older age  ≥ 30 years, working for ≥40 h/week, having safety-related training, and working in ophthalmologic and gynecologic operation rooms were found associated with having a favorable attitude toward perioperative safety.

背景:患者安全是优质医疗服务的基础,也是医疗系统的重中之重。维护患者安全可以减少患者在医疗过程中可能遭受的错误和伤害。手术室临床医生在确保患者安全方面起着至关重要的作用。本研究的总体目标是评估埃塞俄比亚西北部贡达尔大学综合专科医院(UoGCSH)手术室临床医生对围手术期安全的态度及相关因素:已获得贡德尔大学医学院麻醉系的伦理批准。对 UoGCSH 的手术室临床医生进行了横断面研究。数据收集采用自填式结构问卷,其中包括安全态度问卷(SAQ)。采用二元逻辑回归分析,以调整后的几率和 95% 的置信区间来描述相关性的强度:共有 260 名(回复率 76%)手术室临床医生参与了这项研究。对围术期安全态度的平均值(± SD)为 57.8 ± 0.9。只有 32 名(12.3%)手术室临床医生对围术期安全持积极态度。除压力识别领域外,大多数临床医生对 SAQ 的所有领域均持不利态度。年龄超过 30 岁[AOR:3.1,CI:1.1,8.7,P:0.035]、每周工作时间超过 40 小时[AOR:3.9,CI:1.4,11.1,P:0.01]、在眼科工作[AOR:12.0,CI:3.8,38.8,P <0.001]和妇科工作[AOR:3.6,CI:1.1,12.7 P:0.04]手术室,接受过围手术期安全培训[AOR:2.6,CI:1.1,6.5,P <0.03]与对围手术期安全持良好态度有关:结论:大多数手术室临床医生对围术期安全和 SAQ 的所有领域(压力识别领域除外)均持不利态度。年龄大于 30 岁、每周工作时间超过 40 小时、接受过与安全相关的培训以及在眼科和妇科手术室工作与对围术期安全持积极态度有关。
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引用次数: 0
Addressing the challenge of reducing low-value care. 应对减少低价值护理的挑战。
IF 2.7 4区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-09 DOI: 10.1093/intqhc/mzae061
Rudolf B Kool, Eva W Verkerk, Simone A van Dulmen
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引用次数: 0
Seeking systems-based facilitators of safety and healthcare resilience: a thematic review of incident reports. 寻求以系统为基础的安全和医疗保健复原力促进因素:对事故报告的专题审查。
IF 2.7 4区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-09 DOI: 10.1093/intqhc/mzae057
Catherine Leon, Helen Hogan, Yogini H Jani

Patient safety incident reports are a key source of safety intelligence. This study aimed to explore whether information contained in such reports can elicit facilitators of safety, including responding, anticipating, monitoring, learning, and other mechanisms by which safety is maintained. The review further explored whether, if found, this information could be used to inform safety interventions. Anonymized incident reports submitted between August and October 2020 were obtained from two large teaching hospitals. The Systems Engineering Initiative for Patient Safety (SEIPS) tool and the resilience potentials (responding, anticipating, monitoring, and learning) frameworks guided thematic analysis. SEIPS was used to explore the components of people, tools, tasks, and environments, as well as the interactions between them, which contribute to safety. The resilience potentials provided insight into healthcare resilience at individual, team, and organizational levels. Sixty incident reports were analysed. These included descriptions of all the SEIPS framework components. People used tools such as electronic prescribing systems to perform tasks within different healthcare environments that facilitated safety. All four resilient capacities were identified, with mostly individuals and teams responding to events; however, monitoring, anticipation, and learning were described for individuals, teams, and organizations. Incident reports contain information about safety practices, much of which is not identified by traditional approaches such as root cause analysis. This information can be used to enhance safety enablers and encourage greater proactive anticipation and system-level learning.

背景:患者安全事件报告是安全情报的重要来源。本研究旨在探讨此类报告中包含的信息是否能揭示安全的促进因素,包括应对、预测、监控和学习以及其他维护安全的机制。审查还进一步探讨了如果发现了这些信息,是否可将其用于安全干预措施:从两家大型教学医院获取了 2020 年 8 月至 10 月期间提交的匿名事故报告。患者安全系统工程倡议(SEIPS)工具和恢复潜力(响应、预测、监控和学习)框架为主题分析提供了指导。SEIPS 用于探索人员、工具、任务和环境的组成部分,以及这些组成部分之间有助于安全的相互作用。复原力潜能提供了对个人、团队和组织层面的医疗复原力的深入了解:对 60 份事故报告进行了分析。结果:对 60 份事故报告进行了分析,其中包括对 SEIPS 框架所有组成部分的描述。人们使用电子处方系统等工具在不同的医疗环境中执行任务,从而促进了安全。所有四种应变能力都得到了确认,其中大部分是个人和团队对事件做出的反应,但也对个人、团队和组织的监测、预测和学习能力进行了描述:事故报告包含有关安全实践的信息,其中许多信息是传统方法(如根本原因分析)无法识别的。这些信息可用于加强安全的促进因素,鼓励更积极主动的预测和系统层面的学习。
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引用次数: 0
The 'Silent Threat' in medical, surgical, and intensive care unit wards: a daytime and nighttime study. 内科、外科和重症监护室病房中的 "无声威胁":日间和夜间研究。
IF 2.7 4区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-09 DOI: 10.1093/intqhc/mzae059
M Emilia Monteiro, Francisca Sarmento, Filipe Froes, Mariana Alves
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引用次数: 0
Expanded perspectives: integrating clinicians' insights for comprehensive patient-reported outcomes in value-based healthcare. 扩展视角:整合临床医生的见解,在基于价值的医疗保健中实现全面的患者报告结果。
IF 2.7 4区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-07-05 DOI: 10.1093/intqhc/mzae058
Serena Barello, Roberto Bergamaschi, Livio Provenzi

The manuscript explores value-based healthcare (VBHC) and its role in assessing healthcare quality beyond clinical metrics. It identifies four value types: personal, technical, allocative, and societal. Emphasizing the integration of diverse stakeholder perspectives, including patients, families, and clinicians, the study highlights the importance of patient- and family-reported measures (PROMs and PREMs) and clinician input. Clinicians' insights on treatment feasibility and effectiveness are crucial for a holistic understanding of healthcare quality. The manuscript advocates for combining machine learning with participatory approaches to enhance data analysis and continuous quality improvement in VBHC, driving better outcomes for patients and communities.

该手稿探讨了基于价值的医疗保健(VBHC)及其在评估医疗保健质量方面的作用,而不仅仅是临床指标。它确定了四种价值类型:个人价值、技术价值、分配价值和社会价值。该研究强调整合包括患者、家属和临床医生在内的不同利益相关者的观点,突出了患者和家属报告的衡量标准(PROMs 和 PREMs)以及临床医生意见的重要性。临床医生对治疗可行性和有效性的见解对于全面了解医疗质量至关重要。该手稿提倡将机器学习与参与式方法相结合,以加强数据分析和持续改进非住院医疗质量,从而为患者和社区带来更好的治疗效果。
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引用次数: 0
Prescribing antibiotics for children with dengue infection in Taiwan: who are at risk and who are high prescribers? 台湾为感染登革热的儿童开具抗生素处方:谁是高危人群?
IF 2.7 4区 医学 Q1 Medicine Pub Date : 2024-06-25 DOI: 10.1093/intqhc/mzae052
Yi-Jung Shen, Chia-En Lien, Yiing-Jenq Chou, Theodore Tsai, Nicole Huang

Inappropriate antibiotic use contributes to antimicrobial resistance, a global public health threat. The non-specific manifestations of dengue, itself a growing public health threat, lead to avoidable empiric antibiotic prescription, particularly in children. In this national pooled population-based cross-sectional study, we evaluated child and physician characteristics associated with antibiotics prescription in confirmed dengue cases in Taiwan. Linking national health care insurance claims and reports of confirmed dengue cases from 2008 to 2015, there were 7086 children with confirmed dengue with 21 744 outpatient visits and 2520 inpatient admissions. We assessed the presence of antibiotic prescription in outpatient and inpatient settings separately a week before or after the confirmation date. Logistic regression models with generalized estimating equations were applied to identify patient, practitioner, and other factors associated with antibiotic prescription. A total of 29.4% of children <18 years old with dengue who did not have a concomitant bacterial infection were prescribed antibiotics during the 14-day assessment period. Antibiotics prescription was reduced from 13.5% to 6.3% and from 43.2% to 19.3% in outpatient and inpatient settings, respectively, after dengue was confirmed. Young children were more likely to receive antibiotics. Significant variations in antibiotic prescribing across physicians were observed only in outpatient settings: physicians ≥60 years old and physicians practicing at clinics and in non-urban facilities were more likely to prescribe antibiotics. Antibiotics were less likely to be prescribed during an exceptional 2-year epidemic than in other years. Antibiotic prescribing for dengue, an arboviral infection affecting half of the global population, was shown to occur in 29% of paediatric cases in Taiwan. That potentially avoidable antibiotic consumption could be reduced by improving antibiotic stewardship, informed by understanding the conditions under which antibiotics are prescribed and the availability of prevention strategies for viral diseases, including dengue. We identified a number of such factors in this national population-based study.

背景:抗生素使用不当会导致抗菌药耐药性,对全球公共卫生构成威胁。登革热本身是一种日益严重的公共卫生威胁,其非特异性表现导致了可避免的经验性抗生素处方,尤其是在儿童中。在一项基于人口的全国性横断面研究中,我们评估了与台湾登革热确诊病例抗生素处方相关的儿童和医生特征:将 2008 年至 2015 年期间的全国医疗保险报销单和登革热确诊病例报告联系起来,共有 7086 名儿童确诊为登革热,门诊就诊 21744 人次,住院 2520 人次。我们分别评估了确诊日期前后一周门诊和住院环境中抗生素处方的存在情况。结果发现:在 14 天的评估期内,29.4% 的 18 岁以下登革热患儿在没有并发细菌感染的情况下使用了抗生素。确诊登革热后,门诊和住院环境中的抗生素处方率分别从 13.5% 降至 6.3%,从 43.2% 降至 19.3%。幼儿更容易接受抗生素治疗。仅在门诊环境中观察到不同医生在开具抗生素处方方面存在显著差异:年龄超过 60 岁的医生以及在诊所和非城市设施中执业的医生更有可能开具抗生素处方。与其他年份相比,在为期两年的特殊疫情期间,医生更少开具抗生素处方:结论:登革热是一种影响全球半数人口的虫媒病毒感染,在台湾,29% 的儿科病例中都使用了抗生素。通过了解处方抗生素的条件以及包括登革热在内的病毒性疾病的预防策略,提高抗生素管理水平,可以减少潜在的可避免的抗生素消耗。在这项以全国人口为基础的研究中,我们发现了一些此类因素。
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引用次数: 0
期刊
International Journal for Quality in Health Care
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