Pub Date : 2023-01-01DOI: 10.22271/27069567.2023.v5.i1b.455
Dr. Deepshikha Bhalse, Dolly Joseph, D. R. Jha
{"title":"To study mean platelet volume-platelet count ratio in assessing severity in COVID-19 patients","authors":"Dr. Deepshikha Bhalse, Dolly Joseph, D. R. Jha","doi":"10.22271/27069567.2023.v5.i1b.455","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i1b.455","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82959471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.22271/27069567.2023.v5.i1b.468
Nabil Mahmoud Lasheen, A. Elsawy, Tamer Abdelhamed Elbedewy, M. Enaba, H. M. Hegazy
{"title":"Outcomes of endoscopic papillary large balloon dilatation in comparison to mechanical lithotripsy for large common bile duct stone","authors":"Nabil Mahmoud Lasheen, A. Elsawy, Tamer Abdelhamed Elbedewy, M. Enaba, H. M. Hegazy","doi":"10.22271/27069567.2023.v5.i1b.468","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i1b.468","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85589993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.22271/27069567.2023.v5.i1a.430
Dr. K. Anandha Kumar, Dr. Nihar Patidar, D. R. Jha, Dr. Subodh Banzal
{"title":"Assessment of metabolic syndrome in type 2 diabetes mellitus","authors":"Dr. K. Anandha Kumar, Dr. Nihar Patidar, D. R. Jha, Dr. Subodh Banzal","doi":"10.22271/27069567.2023.v5.i1a.430","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i1a.430","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"1201 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79931901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.22271/27069567.2023.v5.i1a.432
Georgios Pittaras, Paris Iakovidis, Konstantinos Kasimis, Antonis Fetlis, D. Lytras, Evangelia Papatheodorou
{"title":"The effect of strengthening and balance programs on preventing falls in the elderly: A systematic review","authors":"Georgios Pittaras, Paris Iakovidis, Konstantinos Kasimis, Antonis Fetlis, D. Lytras, Evangelia Papatheodorou","doi":"10.22271/27069567.2023.v5.i1a.432","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i1a.432","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80033041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.22271/27069567.2023.v5.i1b.469
K. Naeem, Ruchi Baraya, Pramod Chabrani
Although primary PCI remains the preferred strategy for the treatment of STEMI, the lack of expanded PCI centers and prolonged transfer times have resulted in delayed reperfusion and thus increased mortality. A pharmacoinvasive strategy involving immediate fibrinolysis followed by transfer to a PCI center to perform angiography (and PCI of infarct-related arteries) within 2 and 24 hours after successful fibrinolysis offers immediate reperfusion and better outcomes in patients in whom primary PCI could not be achieved in a timely manner without an increase in bleeding complications. The article summarizes the evidence for this approach in terms of efficacy and safety
{"title":"Providing best practices for the management of ST-segment elevation myocardial infarction (STEMI): Pharmacoinvasive strategies","authors":"K. Naeem, Ruchi Baraya, Pramod Chabrani","doi":"10.22271/27069567.2023.v5.i1b.469","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i1b.469","url":null,"abstract":"Although primary PCI remains the preferred strategy for the treatment of STEMI, the lack of expanded PCI centers and prolonged transfer times have resulted in delayed reperfusion and thus increased mortality. A pharmacoinvasive strategy involving immediate fibrinolysis followed by transfer to a PCI center to perform angiography (and PCI of infarct-related arteries) within 2 and 24 hours after successful fibrinolysis offers immediate reperfusion and better outcomes in patients in whom primary PCI could not be achieved in a timely manner without an increase in bleeding complications. The article summarizes the evidence for this approach in terms of efficacy and safety","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79261375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.22271/27069567.2023.v5.i1b.449
Dr. Ravikumar Ughreja
{"title":"Prospective analysis of serum albumin level as prognostic indicator in acute ischemic stroke","authors":"Dr. Ravikumar Ughreja","doi":"10.22271/27069567.2023.v5.i1b.449","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i1b.449","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88075201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.22271/27069567.2023.v5.i1a.446
Dr. Neeraj Sharma, Dr. Munisha Sharma, H. Sethi, Harleen Kaur
{"title":"A study on three rotary retreatment systems in removing Gutta-percha and sealer","authors":"Dr. Neeraj Sharma, Dr. Munisha Sharma, H. Sethi, Harleen Kaur","doi":"10.22271/27069567.2023.v5.i1a.446","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i1a.446","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85260520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-31DOI: 10.24321/2349.7181.202211
O. Bharti
Rabies is a zoonotic viral disease that affects the central nervous system leading to respiratory or cardiac failure. Dogs are a major source of rabies infection in human beings. Rabies is 100% fatal but largely preventable if proper and timely Post-Exposure Prophylaxis (PEP) is availed in the form of immediate wound wash with soap and water and injections of vaccine and rabies immunoglobulins, the first week being the most important. Here we describe four cases of PEP failure despite complete prophylaxis with vaccine and Rabies Immunoglobulins (RIG) over the past year in Himachal Pradesh. All failures were due to suspected rabid dog bites on the face, especially on cheeks, lips, or eyes where complete infiltration of RIG may not have been possible leading to PEP failure. We, after extensive research and discussion, are of the opinion that in such situations, we may add another viricidal oral drug favipiravir along with rabies PEP that could help prevent PEP failures in situations where complete RIG infiltration into wounds is difficult to achieve.
{"title":"Should Favipiravir be Used as an Additional Drug in Case of Severe Animal Bites on the Face Especially into the Eyes/ Lips or Aerosol Exposure to Rabies Virus to Prevent Rabies PEP Failures?","authors":"O. Bharti","doi":"10.24321/2349.7181.202211","DOIUrl":"https://doi.org/10.24321/2349.7181.202211","url":null,"abstract":"Rabies is a zoonotic viral disease that affects the central nervous system leading to respiratory or cardiac failure. Dogs are a major source of rabies infection in human beings. Rabies is 100% fatal but largely preventable if proper and timely Post-Exposure Prophylaxis (PEP) is availed in the form of immediate wound wash with soap and water and injections of vaccine and rabies immunoglobulins, the first week being the most important. Here we describe four cases of PEP failure despite complete prophylaxis with vaccine and Rabies Immunoglobulins (RIG) over the past year in Himachal Pradesh. All failures were due to suspected rabid dog bites on the face, especially on cheeks, lips, or eyes where complete infiltration of RIG may not have been possible leading to PEP failure. We, after extensive research and discussion, are of the opinion that in such situations, we may add another viricidal oral drug favipiravir along with rabies PEP that could help prevent PEP failures in situations where complete RIG infiltration into wounds is difficult to achieve.","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"296 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86756750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-31DOI: 10.24321/2349.7181.202215
Chetan Garg
comorbidities affecting the patient determine the severity. Method: The place of study was Lok Nayak Hospital located in New Delhi. The type of study was prospective observational. The incorporation of 112 subjects was done for the study on the basis of inclusion criteria. Informed consent was obtained from the patients after which they underwent rigorous history taking, general and systemic examination and relevant investigations. Interpretation and compilation were done with MS Excel (R) Office 365, GraphPad Prism 8.4.2 and Statistical Package for Social Sciences version 25. Seroprevalence was estimated by measuring the COVID-19 antibodies in these patients’ serum with an ELISA kit. Results: Seroprevalence in the current study came out to be 13.39%, which was significantly lower as compared to the overall pooled seroprevalence of India. This was due to better knowledge, awareness and care taken by these patients towards the disease during the pandemic times. COVID-19 antibody index was in low ranges in patients with haemophilia (PWH) and further exploration and subsequent seroprevalence studies are needed to monitor the antibody index. Conclusion: Many factors contribute to the seroprevalence of COVID-19, including demographic profile, occupation, socio-economic status of the country, and personal protective measures taken. Seroprevalence studies are important in making healthcare policies and prioritisation in the early rollout of vaccination for susceptible groups of people and their protection.
影响患者的合并症决定了严重程度。方法:研究地点为位于新德里的Lok Nayak医院。研究类型为前瞻性观察性研究。根据纳入标准纳入112名受试者进行研究。在获得患者知情同意后，患者接受了严格的病史记录、全面和系统检查以及相关调查。使用MS Excel (R) Office 365、GraphPad Prism 8.4.2和Statistical Package for Social Sciences version 25进行解译和编译。采用ELISA试剂盒检测患者血清中COVID-19抗体，估计血清阳性率。结果:本研究血清阳性率为13.39%，与印度整体血清阳性率相比显著降低。这是由于这些患者在大流行期间对该疾病有了更好的了解、认识和护理。血友病(PWH)患者的COVID-19抗体指数处于较低水平，需要进一步探索和后续的血清阳性率研究来监测抗体指数。结论:影响COVID-19血清阳性率的因素很多，包括人口结构、职业、国家社会经济状况、个人防护措施等。血清阳性率研究对于制定卫生保健政策和确定早期为易感人群接种疫苗的优先顺序及其保护具有重要意义。
{"title":"Seroprevalence of COVID-19 Antibodies among Patients with Haemophilia","authors":"Chetan Garg","doi":"10.24321/2349.7181.202215","DOIUrl":"https://doi.org/10.24321/2349.7181.202215","url":null,"abstract":"comorbidities affecting the patient determine the severity. Method: The place of study was Lok Nayak Hospital located in New Delhi. The type of study was prospective observational. The incorporation of 112 subjects was done for the study on the basis of inclusion criteria. Informed consent was obtained from the patients after which they underwent rigorous history taking, general and systemic examination and relevant investigations. Interpretation and compilation were done with MS Excel (R) Office 365, GraphPad Prism 8.4.2 and Statistical Package for Social Sciences version 25. Seroprevalence was estimated by measuring the COVID-19 antibodies in these patients’ serum with an ELISA kit. Results: Seroprevalence in the current study came out to be 13.39%, which was significantly lower as compared to the overall pooled seroprevalence of India. This was due to better knowledge, awareness and care taken by these patients towards the disease during the pandemic times. COVID-19 antibody index was in low ranges in patients with haemophilia (PWH) and further exploration and subsequent seroprevalence studies are needed to monitor the antibody index. Conclusion: Many factors contribute to the seroprevalence of COVID-19, including demographic profile, occupation, socio-economic status of the country, and personal protective measures taken. Seroprevalence studies are important in making healthcare policies and prioritisation in the early rollout of vaccination for susceptible groups of people and their protection.","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84109518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-21DOI: 10.24321/2349.7181.202214
Manisha V Prabhu
Sheehan syndrome is a rare complication of postpartum haemorrhage resulting in pituitary necrosis and panhypopituitarism. We report a case of a 52-year-old female who presented with easy fatigability, asthenia and loss of appetite for 8-10 months. She was found to have alopecia, hypotension, hypoglycaemia, pancytopenia, and a history of failure to lactate after the last childbirth (17 years back) with premature menopause. The hormone profile revealed panhypopituitarism and magnetic resonance imaging of the brain was suggestive of partially empty sella. Her echocardiogram showed dilated cardiomyopathy with an ejection fraction of 35%. A diagnosis of Sheehan syndrome presenting with pancytopenia and dilated cardiomyopathy was made. The patient was started on injectable hydrocortisone and later, on thyroid hormone supplementation after which she improved. Sheehan syndrome is responsive to hormone replacement therapy and therefore should always be ruled out in such patients.
{"title":"A Case of Sheehan Syndrome Presenting with Pancytopenia and Dilated Cardiomyopathy: A Rare Combination","authors":"Manisha V Prabhu","doi":"10.24321/2349.7181.202214","DOIUrl":"https://doi.org/10.24321/2349.7181.202214","url":null,"abstract":"Sheehan syndrome is a rare complication of postpartum haemorrhage resulting in pituitary necrosis and panhypopituitarism. We report a case of a 52-year-old female who presented with easy fatigability, asthenia and loss of appetite for 8-10 months. She was found to have alopecia, hypotension, hypoglycaemia, pancytopenia, and a history of failure to lactate after the last childbirth (17 years back) with premature menopause. The hormone profile revealed panhypopituitarism and magnetic resonance imaging of the brain was suggestive of partially empty sella. Her echocardiogram showed dilated cardiomyopathy with an ejection fraction of 35%. A diagnosis of Sheehan syndrome presenting with pancytopenia and dilated cardiomyopathy was made. The patient was started on injectable hydrocortisone and later, on thyroid hormone supplementation after which she improved. Sheehan syndrome is responsive to hormone replacement therapy and therefore should always be ruled out in such patients.","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79315798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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