Background: Dengue remains a significant public health challenge, especially in pediatric populations. This study aims to analyze the demographic distribution, clinical presentation, and outcomes of severe dengue in children, with a focus on identifying key factors associated with recovery and mortality.Methods: This cross-sectional analytical study was conducted on 300 children diagnosed with severe dengue at Dhaka Shishu (Children) hospital, Bangladesh, from January 2019 to December 2020. Participants were selected using convenient sampling, and data on demographic characteristics, clinical symptoms, and physical examination findings were collected and analyzed using SPSS V. 22.Result: The study included a majority in the 6-10 years age group (56.67%), with a male predominance (59.33%). Major bleeding was observed in 27.33% of participants. The mortality rate was 4.67%. No significant differences in age and gender distribution were found between the recovery and mortality groups. Symptoms like cough, breathlessness, and abdominal pain, along with physical findings such as increased hematocrit, pleural effusion, and hepatomegaly, were significantly associated with mortality.Conclusions: Severe dengue in children presents with a range of symptoms, with major bleeding being a critical indicator of disease severity. The study highlights the need for comprehensive clinical assessment and vigilant monitoring, emphasizing the importance of recognizing both common and severe symptoms in pediatric dengue for effective management and improved outcomes.
{"title":"Assessment of risk factors and early warning signs for mortality in children with severe dengue at tertiary care hospital, Dhaka, Bangladesh: a prospective observational study","authors":"Moshrefa Newaz, M. Hoque, Mashhura Huq, Sabrina Akter, Tahera Nasrin, Fahmida Hossain, Afsana Khanom","doi":"10.18203/2349-3291.ijcp20242011","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20242011","url":null,"abstract":"Background: Dengue remains a significant public health challenge, especially in pediatric populations. This study aims to analyze the demographic distribution, clinical presentation, and outcomes of severe dengue in children, with a focus on identifying key factors associated with recovery and mortality.\u0000Methods: This cross-sectional analytical study was conducted on 300 children diagnosed with severe dengue at Dhaka Shishu (Children) hospital, Bangladesh, from January 2019 to December 2020. Participants were selected using convenient sampling, and data on demographic characteristics, clinical symptoms, and physical examination findings were collected and analyzed using SPSS V. 22.\u0000Result: The study included a majority in the 6-10 years age group (56.67%), with a male predominance (59.33%). Major bleeding was observed in 27.33% of participants. The mortality rate was 4.67%. No significant differences in age and gender distribution were found between the recovery and mortality groups. Symptoms like cough, breathlessness, and abdominal pain, along with physical findings such as increased hematocrit, pleural effusion, and hepatomegaly, were significantly associated with mortality.\u0000Conclusions: Severe dengue in children presents with a range of symptoms, with major bleeding being a critical indicator of disease severity. The study highlights the need for comprehensive clinical assessment and vigilant monitoring, emphasizing the importance of recognizing both common and severe symptoms in pediatric dengue for effective management and improved outcomes.\u0000 ","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"19 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141800895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Adolescence is a transitional phase of physical and psychological development and is characterized by emotional turmoil, anxiety, increase in risk taking behaviour and seeking comfort in peers rather than parents. Taking into account these factors, government has started certain programmes for welfare of adolescent youth, and here we aim to study various services provided to the adolescents, under adolescent health friendly clinic in Himachal which are started under National adolescent health programme.Methods: Adolescent data is obtained from public domain about the services and facilities provided to the adolescent girls and boys at various adolescent health friendly clinic established in various districts of Himachal Pradesh. The data is taken from January 2021 to December 2023 for 2 years.Results: In total of 103 adolescent health friendly clinic, 44% of adolescent received clinical services, 47% of adolescent received counselling services and 9% of the adolescent received referral to other departments to seek specialized care.Conclusions: During adolescence, individuals have unique health and rights requirements and with access to appropriate experiences and rights, individuals can pave the way for a brighter future and contribute significantly to the strength of their nation.
{"title":"Services provided by the adolescent health friendly clinics in the state of Himachal Pradesh, India: an overview","authors":"Anjali Chauhan, Aaina Sharma, Gaurav Sethi, Manisha Bhatia","doi":"10.18203/2349-3291.ijcp20242019","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20242019","url":null,"abstract":"Background: Adolescence is a transitional phase of physical and psychological development and is characterized by emotional turmoil, anxiety, increase in risk taking behaviour and seeking comfort in peers rather than parents. Taking into account these factors, government has started certain programmes for welfare of adolescent youth, and here we aim to study various services provided to the adolescents, under adolescent health friendly clinic in Himachal which are started under National adolescent health programme.\u0000Methods: Adolescent data is obtained from public domain about the services and facilities provided to the adolescent girls and boys at various adolescent health friendly clinic established in various districts of Himachal Pradesh. The data is taken from January 2021 to December 2023 for 2 years.\u0000Results: In total of 103 adolescent health friendly clinic, 44% of adolescent received clinical services, 47% of adolescent received counselling services and 9% of the adolescent received referral to other departments to seek specialized care.\u0000Conclusions: During adolescence, individuals have unique health and rights requirements and with access to appropriate experiences and rights, individuals can pave the way for a brighter future and contribute significantly to the strength of their nation.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"119 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141802031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-26DOI: 10.18203/2349-3291.ijcp20242010
M. Shahjahan, Khondaker M. Elahi, Nusrat J. Nrjana, M. K. Islam
Background: There are several challenges at the global and national levels that contribute to surgery in children's health. The aim of the study was to evaluate the surgical problems in children in Dhaka Shishu Hospital-that is in Bangladesh.Methods: This retrospective study was carried out in the department of pediatric surgery, Dhaka Shishu Hospital. A retrospective study of surgical problems in children’s in the last 10 (September 2013 to October 2023) years were done in admitted patients in the surgery department. A total of 12689 patients were participated in the study. The surgical units of this hospital contain 100 beds. So, the average total number of surgical patients are 200. This is for the first time in our country an attempt is made to present a data of surgical problems in children’s in Bangladesh in the experience of Dhaka Shishu Hospital. Statistical analyses of the results were obtained by using statistical packages for social sciences (SPSS-24).Results: A total number of 12689 patients; aged <10 years; admitted in the surgical units of Dhaka Shishu Hospital in the last 10 years were reviewed. Male patients were 59%, female 42%. Among them 29% were of age below 1 year, 43% from 1 to 5 years and 29% were above 5 years. Gastro-intestinal disorders were the commonest problem observed-constituting 43.9% of cases, while 9.2% of children came with burn injury.Conclusions: The management of surgical problems often requires a multidisciplinary approach and advancements in surgical techniques, anesthesia, and perioperative care have improved the surgical interventions in pediatric patients over the years.
{"title":"Common paediatric surgical problems in Bangladesh: experience in tertiary care center, Dhaka, Bangladesh","authors":"M. Shahjahan, Khondaker M. Elahi, Nusrat J. Nrjana, M. K. Islam","doi":"10.18203/2349-3291.ijcp20242010","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20242010","url":null,"abstract":"Background: There are several challenges at the global and national levels that contribute to surgery in children's health. The aim of the study was to evaluate the surgical problems in children in Dhaka Shishu Hospital-that is in Bangladesh.\u0000Methods: This retrospective study was carried out in the department of pediatric surgery, Dhaka Shishu Hospital. A retrospective study of surgical problems in children’s in the last 10 (September 2013 to October 2023) years were done in admitted patients in the surgery department. A total of 12689 patients were participated in the study. The surgical units of this hospital contain 100 beds. So, the average total number of surgical patients are 200. This is for the first time in our country an attempt is made to present a data of surgical problems in children’s in Bangladesh in the experience of Dhaka Shishu Hospital. Statistical analyses of the results were obtained by using statistical packages for social sciences (SPSS-24).\u0000Results: A total number of 12689 patients; aged <10 years; admitted in the surgical units of Dhaka Shishu Hospital in the last 10 years were reviewed. Male patients were 59%, female 42%. Among them 29% were of age below 1 year, 43% from 1 to 5 years and 29% were above 5 years. Gastro-intestinal disorders were the commonest problem observed-constituting 43.9% of cases, while 9.2% of children came with burn injury.\u0000Conclusions: The management of surgical problems often requires a multidisciplinary approach and advancements in surgical techniques, anesthesia, and perioperative care have improved the surgical interventions in pediatric patients over the years.\u0000 ","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"39 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141798748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Adolescents constitute a major group of population in India. Mental health problems are not so uncommon among them. Since there is lack of awareness concerning the seriousness of mental ill health and it’s adverse effects on growing population it is essential to have an estimate of percentage of adolescent population effected.Methods: It is a cross-sectional study conducted in a school on 330 students studying in 9th to 12th std in Raichur district. Mental health was assessed by questionnaire called Warwick Edinburg mental wellness score.Results: Overall, 14.2% of adolescents had poor mental health scores which was more among girls in comparison to boys.Conclusions: The prevalence of mental health issues among adolescents is rising concern that requires proper attention and action by health care providers, educators, and parents of the child. Early intervention is essential to ensure the well-being of young people.
{"title":"Prevalence of mental health issues among adolescents","authors":"Kavya Vijaykumar, Usha Hirevenkanagoudar, Sanjeev Chetty","doi":"10.18203/2349-3291.ijcp20242018","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20242018","url":null,"abstract":"Background: Adolescents constitute a major group of population in India. Mental health problems are not so uncommon among them. Since there is lack of awareness concerning the seriousness of mental ill health and it’s adverse effects on growing population it is essential to have an estimate of percentage of adolescent population effected.\u0000Methods: It is a cross-sectional study conducted in a school on 330 students studying in 9th to 12th std in Raichur district. Mental health was assessed by questionnaire called Warwick Edinburg mental wellness score.\u0000Results: Overall, 14.2% of adolescents had poor mental health scores which was more among girls in comparison to boys.\u0000Conclusions: The prevalence of mental health issues among adolescents is rising concern that requires proper attention and action by health care providers, educators, and parents of the child. Early intervention is essential to ensure the well-being of young people.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"61 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141798791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-26DOI: 10.18203/2349-3291.ijcp20242006
Nika Vashakidze, Elisabed Chikobava, Gvantsa Jatchvadze, Yash Sailesh Kumar, Ahmed Ullah, Karishma R. Salian, Elene Janukashvili
Background: Breast milk is suggested as the ideal and sole early nutrition source for infants from birth to at least six months of age and should be viewed as a public health concern rather than a personal preference. Human milk banks (HMBs) play a crucial role in providing life-saving breast milk to premature and ill infants when maternal milk is unavailable. Georgia has ongoing efforts to establish the first official HMB facility.Methods: We conducted a cross-sectional study employing a simple random sampling method to select a sample of 287 women of reproductive age and to assess their knowledge and attitude toward HMBs.Results: Despite a substantial knowledge gap (57% recognizing nutritional superiority, 51% acknowledging infection risk reduction), the main issue is low trust (30%) in future local milk banking facilities; if unable to produce milk, only 30% of women prefer donated human milk over formula. A statistically significant association has been recorded between personal neonatal intensive care unit admission history, higher educational status, and a more positive attitude toward HMBs.Conclusions: This study provides a foundational basis for future healthcare initiatives to enhance acceptance and knowledge of HMBs, facilitating the optimal functioning of these facilities within the population.
{"title":"Knowledge and attitude towards human milk banking in reproductive aged women living in Georgia","authors":"Nika Vashakidze, Elisabed Chikobava, Gvantsa Jatchvadze, Yash Sailesh Kumar, Ahmed Ullah, Karishma R. Salian, Elene Janukashvili","doi":"10.18203/2349-3291.ijcp20242006","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20242006","url":null,"abstract":"Background: Breast milk is suggested as the ideal and sole early nutrition source for infants from birth to at least six months of age and should be viewed as a public health concern rather than a personal preference. Human milk banks (HMBs) play a crucial role in providing life-saving breast milk to premature and ill infants when maternal milk is unavailable. Georgia has ongoing efforts to establish the first official HMB facility.\u0000Methods: We conducted a cross-sectional study employing a simple random sampling method to select a sample of 287 women of reproductive age and to assess their knowledge and attitude toward HMBs.\u0000Results: Despite a substantial knowledge gap (57% recognizing nutritional superiority, 51% acknowledging infection risk reduction), the main issue is low trust (30%) in future local milk banking facilities; if unable to produce milk, only 30% of women prefer donated human milk over formula. A statistically significant association has been recorded between personal neonatal intensive care unit admission history, higher educational status, and a more positive attitude toward HMBs.\u0000Conclusions: This study provides a foundational basis for future healthcare initiatives to enhance acceptance and knowledge of HMBs, facilitating the optimal functioning of these facilities within the population.\u0000 ","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"44 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141800157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-26DOI: 10.18203/2349-3291.ijcp20242029
Priyanka J. Rabadia, Bhavi M. Makwana, Sonal Shah
Goldberg-Shprintzen syndrome is an autosomal dominant disorder caused by mutations in the KIFBP gene, which encodes the kinesin family binding protein. This protein is essential for cytoskeleton formation and neurite growth, interacting with microtubules and actin filaments. Initially, the patient was suspected to have meconium ileus with intestinal obstruction or cystic fibrosis, but further investigations revealed Goldberg-Shprintzen syndrome. To date, fewer than 50 cases have been reported in the medical literature. This case review aims to increase awareness of this rare connective tissue disorder, which remains underdiagnosed due to the scarcity of documented cases and some overlap with other syndromes.
{"title":"A rare case report of Goldberg-Shprintzen syndrome","authors":"Priyanka J. Rabadia, Bhavi M. Makwana, Sonal Shah","doi":"10.18203/2349-3291.ijcp20242029","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20242029","url":null,"abstract":"Goldberg-Shprintzen syndrome is an autosomal dominant disorder caused by mutations in the KIFBP gene, which encodes the kinesin family binding protein. This protein is essential for cytoskeleton formation and neurite growth, interacting with microtubules and actin filaments. Initially, the patient was suspected to have meconium ileus with intestinal obstruction or cystic fibrosis, but further investigations revealed Goldberg-Shprintzen syndrome. To date, fewer than 50 cases have been reported in the medical literature. This case review aims to increase awareness of this rare connective tissue disorder, which remains underdiagnosed due to the scarcity of documented cases and some overlap with other syndromes.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"25 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141800821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-26DOI: 10.18203/2349-3291.ijcp20242024
S. A. Nandimath, Rajkumar G. C., Kshitija Patil, Mala M.
Oral and maxillofacial surgical procedures in children necessitate special considerations due to ongoing development. Key factors include obtaining parental consent, understanding developing anatomy and dentition, potential adverse effects on growth, behavioural guidance, and comprehensive peri- and postoperative care. This paper aims to outline the key considerations and challenges in managing paediatric oral and maxillofacial conditions. It seeks to review various treatment approaches for common conditions such as temporomandibular joint (TMJ) ankylosis, odontogenic cysts, tumours, maxillofacial trauma, and infections. Case studies are presented to illustrate various conditions and their management, reflecting contemporary practices and treatment strategies. The cases demonstrate diverse management approaches for paediatric oral and maxillofacial conditions. Dentigerous cysts and aggressive ossifying fibromas were treated with surgical interventions, including enucleation and reconstruction. TMJ ankylosis was addressed through aggressive resection and joint reconstruction, followed by intensive physiotherapy. Fractures and trauma cases were managed conservatively or with specialized techniques, such as botulinum toxin injections, highlighting the necessity for individualized treatment based on the specific injury and patient condition. Managing paediatric oral and maxillofacial conditions requires a tailored approach that balances effective treatment with the preservation of growth potential. Strategies must be adapted to accommodate the dynamic nature of growth and development in children, and regular follow-up is essential for monitoring outcomes and adjusting treatment plans as needed.
{"title":"Unravelling the vital role of maxillofacial surgeons in paediatric oral and maxillofacial surgery: a case series","authors":"S. A. Nandimath, Rajkumar G. C., Kshitija Patil, Mala M.","doi":"10.18203/2349-3291.ijcp20242024","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20242024","url":null,"abstract":"Oral and maxillofacial surgical procedures in children necessitate special considerations due to ongoing development. Key factors include obtaining parental consent, understanding developing anatomy and dentition, potential adverse effects on growth, behavioural guidance, and comprehensive peri- and postoperative care. This paper aims to outline the key considerations and challenges in managing paediatric oral and maxillofacial conditions. It seeks to review various treatment approaches for common conditions such as temporomandibular joint (TMJ) ankylosis, odontogenic cysts, tumours, maxillofacial trauma, and infections. Case studies are presented to illustrate various conditions and their management, reflecting contemporary practices and treatment strategies. The cases demonstrate diverse management approaches for paediatric oral and maxillofacial conditions. Dentigerous cysts and aggressive ossifying fibromas were treated with surgical interventions, including enucleation and reconstruction. TMJ ankylosis was addressed through aggressive resection and joint reconstruction, followed by intensive physiotherapy. Fractures and trauma cases were managed conservatively or with specialized techniques, such as botulinum toxin injections, highlighting the necessity for individualized treatment based on the specific injury and patient condition. Managing paediatric oral and maxillofacial conditions requires a tailored approach that balances effective treatment with the preservation of growth potential. Strategies must be adapted to accommodate the dynamic nature of growth and development in children, and regular follow-up is essential for monitoring outcomes and adjusting treatment plans as needed.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"115 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141802108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Respiratory tract infections (RTIs) caused by various viruses and microbial agents present clinical challenges due to their diverse presentations. This retrospective study aimed to identify epidemiological trends and clinical characteristics of RTIs in pediatric populations using molecular diagnosis.Methods: The study cohort comprised 100 paediatric individuals, predominantly male (70%) compared to female (30%), distributed across different age brackets. Real Time PCR targeting 32 microbial pathogens includes bacteria (15) and viruses (17).Results: The majority of participants were aged 1 to 12 months (38%), followed by 1 to 3 years (29%), and 3 to 10 years (25%), with the smallest group being infants under 1 month (8%). A total of 134 pathogens were detected in 100 patients, with a higher prevalence in males (80%) compared to females (20%). Human respiratory syncytial viruses A and B were the most common, with 17 cases in males and 5 in females. Klebsiella pneumonia followed, with 19 cases in males and 5 in females. Influenza A and B viruses were also notable, with 7 and 9 cases in males, and 4 and 7 cases in females, respectively. Other significant microbes included human parainfluenza virus 3, human adenovirus, and Streptococcus pneumoniae. Notably, SARS-CoV-2 and Acinetobacter baumannii were not detected in either gender during the study period.Conclusions: Our study shows that nucleic acid-based tests, especially multiplex PCR, effectively detect respiratory viruses in pediatric RTI patients, reducing inappropriate antibacterial use and mortality/morbidity.
{"title":"Leveraging real-time PCR for early diagnosis of respiratory conditions in the Indian pediatric population","authors":"Murugan Nandagopal, Venugopal Kalyankumar, Murugesan Deepa, Padhiar Chirayu","doi":"10.18203/2349-3291.ijcp20242017","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20242017","url":null,"abstract":"Background: Respiratory tract infections (RTIs) caused by various viruses and microbial agents present clinical challenges due to their diverse presentations. This retrospective study aimed to identify epidemiological trends and clinical characteristics of RTIs in pediatric populations using molecular diagnosis.\u0000Methods: The study cohort comprised 100 paediatric individuals, predominantly male (70%) compared to female (30%), distributed across different age brackets. Real Time PCR targeting 32 microbial pathogens includes bacteria (15) and viruses (17).\u0000Results: The majority of participants were aged 1 to 12 months (38%), followed by 1 to 3 years (29%), and 3 to 10 years (25%), with the smallest group being infants under 1 month (8%). A total of 134 pathogens were detected in 100 patients, with a higher prevalence in males (80%) compared to females (20%). Human respiratory syncytial viruses A and B were the most common, with 17 cases in males and 5 in females. Klebsiella pneumonia followed, with 19 cases in males and 5 in females. Influenza A and B viruses were also notable, with 7 and 9 cases in males, and 4 and 7 cases in females, respectively. Other significant microbes included human parainfluenza virus 3, human adenovirus, and Streptococcus pneumoniae. Notably, SARS-CoV-2 and Acinetobacter baumannii were not detected in either gender during the study period.\u0000Conclusions: Our study shows that nucleic acid-based tests, especially multiplex PCR, effectively detect respiratory viruses in pediatric RTI patients, reducing inappropriate antibacterial use and mortality/morbidity.\u0000 ","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"53 48","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141799699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-26DOI: 10.18203/2349-3291.ijcp20242014
Mallanagouda Kuberagouda Pavadigoudra, Sujata Sajjanar, Uday K., Ushakiran C. B.
Background: As insulin is important regulator of growth hormone related factors, especially insulin like growth factors (IGF-1) and insulin like growth factors binding proteins (IGFBP-3), disorders of insulin production can result in poor growth. Studies suggest that growth abnormalities are common in subjects with poor metabolic control and longer disease duration. Growth parameters are important indicators of a child overall health and they are influenced by factors like blood glucose control in diabetic children.Methods: After obtaining institutional ethical committee clearance and informed consent from parents/subjects, a prospective observational study was conducted from January 2018 to June 2019. Anthropometry of each participant (height, weight, BMI) measured and 4 ml of venous blood was collected for HbA1C levels. Results were compared with age specific standards. Anthropometry and blood investigations performed once in 3 months for 1 year.Results: Out of 30 cases, 53.3% (n=16) were males and 46.7% (n=14) were females with M:F ratio of was 1:1.04. Among those with poor HbA1C control 73.69% (n=14) had short stature at the entry of the study and the results was statistically significant (p=0.043). Among those with poor HbA1C control, 72.73% (n=08) had short stature at the one year follow up and the results was statistically significant (p=0.017). Which suggests that linear growth in children with type 1 diabetes is highly related to glycemic control.Conclusions: Growth was compromised in diabetic children. Children diagnosed at younger age need monitoring of good glycemic control and drug compliance to optimize the growth.
{"title":"Assessment of growth among children with type 1 diabetes mellitus","authors":"Mallanagouda Kuberagouda Pavadigoudra, Sujata Sajjanar, Uday K., Ushakiran C. B.","doi":"10.18203/2349-3291.ijcp20242014","DOIUrl":"https://doi.org/10.18203/2349-3291.ijcp20242014","url":null,"abstract":"Background: As insulin is important regulator of growth hormone related factors, especially insulin like growth factors (IGF-1) and insulin like growth factors binding proteins (IGFBP-3), disorders of insulin production can result in poor growth. Studies suggest that growth abnormalities are common in subjects with poor metabolic control and longer disease duration. Growth parameters are important indicators of a child overall health and they are influenced by factors like blood glucose control in diabetic children.\u0000Methods: After obtaining institutional ethical committee clearance and informed consent from parents/subjects, a prospective observational study was conducted from January 2018 to June 2019. Anthropometry of each participant (height, weight, BMI) measured and 4 ml of venous blood was collected for HbA1C levels. Results were compared with age specific standards. Anthropometry and blood investigations performed once in 3 months for 1 year.\u0000Results: Out of 30 cases, 53.3% (n=16) were males and 46.7% (n=14) were females with M:F ratio of was 1:1.04. Among those with poor HbA1C control 73.69% (n=14) had short stature at the entry of the study and the results was statistically significant (p=0.043). Among those with poor HbA1C control, 72.73% (n=08) had short stature at the one year follow up and the results was statistically significant (p=0.017). Which suggests that linear growth in children with type 1 diabetes is highly related to glycemic control.\u0000Conclusions: Growth was compromised in diabetic children. Children diagnosed at younger age need monitoring of good glycemic control and drug compliance to optimize the growth.","PeriodicalId":13870,"journal":{"name":"International Journal of Contemporary Pediatrics","volume":"37 49","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141800131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-26DOI: 10.18203/2349-3291.ijcp20242016
Asmita Tripathy, Dhara K. Gosai, Gargi H. Pathak, Mehul M. Jadav
Background: Dengue fever is characterized by biphasic fever, myalgia or arthralgia and rash. WHO has estimated that there are 100 million cases and 30,000 deaths worldwide. It is caused by serotypes of dengue virus and transmitted by mosquitoes of Aedes Aegypti. The aim was to study the clinical-epidemiological profile of children with dengue fever.Methods: From January 2020 to December 2020, the baseline survey was conducted in pediatrics department, Civil Hospital, Asarwa, Ahmedabad, India in which the data was confirmed dengue fever with laboratory diagnosis of serology (NS1/IgM) positive in the age group of >6 months and <12 years.Results: In a total of 127 cases of dengue, majority (52%) were in age group of 6-12 years and presented with warning signs (72%). The most common complication and hemorrhagic manifestation were dengue hepatitis (10.5%) and petechiae/purpura (29.1%). Bleeding was common when platelet count was <20000 lakh/mm3. Diagnosis was confirmed with dengue NS1 Ag (71.7%) and serum IgM (100%). Most of the patients recovered with IV fluid therapy (81.9%).Conclusions: Major admissions were in the febrile phase of the disease. NS1Ag, liver function test and ultrasonography play an important role in early diagnosis, early detection of complication and as a prognostic marker for outcome in dengue fever. The mainstay of management is adequate hydration (IV fluids). It was concluded that, prevention is better than cure of the disease in the form of integrated vector management control.
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