Pub Date : 2025-01-05DOI: 10.1016/j.ijoes.2025.100934
Xia Cao , Yafeng He , Sipeng Wang
This study proposes a micromilling-assisted electrochemical machining method to obtain high-quality surfaces on a titanium alloy (Ti6Al4V). This method replaces the traditional mixed electrolyte composed of NaCl and NaNO3 with a highly replication-accurate NaNO3 electrolyte. The passive film on the titanium alloy surface was alternately removed by the cutting action of the micromilling cutters, ensuring smooth progress in electrochemical machining. A theoretical model of the cross-sectional profile of Ti6Al4V micromilling-assisted electrochemical machining was established, and dynamic numerical simulations and process experiments were conducted. The effects of machining voltage, feed speed, and spindle speed on the current density and machining depth were investigated. The results indicated that the machining depth increased with machining voltage and decreased with higher feed and spindle speeds. At a feed speed of 3 mm/min, processing voltage of 24 V, and spindle speed of 2000 r/min, the surface quality of the titanium alloy Ti6Al4V was high, achieving a surface roughness of 1.785 μm. The experimental cross-sectional profile of the composite processing depth aligned well with theoretical predictions.
{"title":"Numerical simulation and experimental study on micromilling-assisted electrochemical machining","authors":"Xia Cao , Yafeng He , Sipeng Wang","doi":"10.1016/j.ijoes.2025.100934","DOIUrl":"10.1016/j.ijoes.2025.100934","url":null,"abstract":"<div><div>This study proposes a micromilling-assisted electrochemical machining method to obtain high-quality surfaces on a titanium alloy (Ti6Al4V). This method replaces the traditional mixed electrolyte composed of NaCl and NaNO<sub>3</sub> with a highly replication-accurate NaNO<sub>3</sub> electrolyte. The passive film on the titanium alloy surface was alternately removed by the cutting action of the micromilling cutters, ensuring smooth progress in electrochemical machining. A theoretical model of the cross-sectional profile of Ti6Al4V micromilling-assisted electrochemical machining was established, and dynamic numerical simulations and process experiments were conducted. The effects of machining voltage, feed speed, and spindle speed on the current density and machining depth were investigated. The results indicated that the machining depth increased with machining voltage and decreased with higher feed and spindle speeds. At a feed speed of 3 mm/min, processing voltage of 24 V, and spindle speed of 2000 r/min, the surface quality of the titanium alloy Ti6Al4V was high, achieving a surface roughness of 1.785 μm. The experimental cross-sectional profile of the composite processing depth aligned well with theoretical predictions.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 3","pages":"Article 100934"},"PeriodicalIF":1.3,"publicationDate":"2025-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143149381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.ijoes.2024.100905
Ping Wang, Lijun Yue
Japanese encephalitis virus (JEV) causes acute inflammation of the brain affecting ∼68,000 annually in Asia. While conventional diagnostics like ELISA take days, this work developed an electrochemical immunosensor for rapid JEV detection at point-of-care. The sensor relied on carbon nanoparticles (CNPs) electrodeposited on screen-printed carbon electrodes (SPCE) and covalently linked with anti-JEV antibodies. Systematic optimization resulted in the optimal antibody concentration of 20 μg/mL with 30 min incubation enabling detection down to 42 fg/mL. The dynamic range spanned 100 fg/mL to 100 ng/mL within analysis time of 30 min. The SPCE-based disposable strip format provided < 8 % variability across electrodes. The CNP interface lowered detection limit by 10x versus earlier nanomaterial-assisted JEV sensors owing to high surface area and conductivity. Potential field deployment challenges include antibody stability for prolonged storage, validation across larger clinical cohorts, ease-of-use via integration with microfluidics/smartphones. Further robustification can enable rapid screening at point-of-care during outbreaks in resource-limited settings.
{"title":"Point-of-care detection of Japanese encephalitis virus based on advanced electrochemical immunosensor","authors":"Ping Wang, Lijun Yue","doi":"10.1016/j.ijoes.2024.100905","DOIUrl":"10.1016/j.ijoes.2024.100905","url":null,"abstract":"<div><div>Japanese encephalitis virus (JEV) causes acute inflammation of the brain affecting ∼68,000 annually in Asia. While conventional diagnostics like ELISA take days, this work developed an electrochemical immunosensor for rapid JEV detection at point-of-care. The sensor relied on carbon nanoparticles (CNPs) electrodeposited on screen-printed carbon electrodes (SPCE) and covalently linked with anti-JEV antibodies. Systematic optimization resulted in the optimal antibody concentration of 20 μg/mL with 30 min incubation enabling detection down to 42 fg/mL. The dynamic range spanned 100 fg/mL to 100 ng/mL within analysis time of 30 min. The SPCE-based disposable strip format provided < 8 % variability across electrodes. The CNP interface lowered detection limit by 10x versus earlier nanomaterial-assisted JEV sensors owing to high surface area and conductivity. Potential field deployment challenges include antibody stability for prolonged storage, validation across larger clinical cohorts, ease-of-use via integration with microfluidics/smartphones. Further robustification can enable rapid screening at point-of-care during outbreaks in resource-limited settings.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 1","pages":"Article 100905"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.ijoes.2024.100922
Li Zhiyong , Azman Jalar , Norinsan Kamil Othman
The content of additive Y has a significant impact on the microstructure and mechanical properties of sintered cemented carbides prepared via powder metallurgy. However, the effects of Y content on the properties of cemented carbides remain poorly understood. This study investigates the effect of the content of Y2O3, introduced via a spray phase transformation process, on the microstructure, mechanical properties, and corrosion resistance of the WC-Co cemented carbide, to advance knowledge in this field. An ultrafine Co-based composite powder containing Y2O3 was synthesised using WC, (CH3COO)2Co·4 H2O, and Y(C2H3O2)3·4 H2O. The powder was prepared via spray conversion, calcination, oxidation, and low-temperature reduction. The WC-8Co-Y2O3 cemented carbide was fabricated through high-energy ball milling and spark plasma sintering to ensure the uniform distribution of the Co bonding phase. The spray transformation process produced irregular amorphous precursor powders containing Co and Y. After calcination, the powders exhibited a reduction in particle size and underwent agglomeration. The ball milling of the WC-8Co-Y2O3 composite powder with added WC further reduced the particle size and intensified agglomeration. An increase in the Y2O3 content resulted in grain refinement and an increase in the number of WC/Co grain boundaries, thereby improving the corrosion resistance of the alloy. The mechanical properties of the alloys exhibited a trend in which the density, Vickers hardness, and fracture toughness initially increased and then decreased with increasing Y2O3 content. At 1.5 wt% Y2O3, these properties reached their maximum values, achieving a relative density of 98.94 %, a Vickers hardness of 2034 HV30, and a fracture toughness of 8.39 MPa·m1/2. The alloy also exhibited optimal corrosion resistance, with Ecorr and icorr values of −252 mV and 6.464 μA/cm2, respectively. The presence of Y2O3 promoted the formation of an ultrafine Co phase, which mitigated dislocation motion, thereby enhancing the mechanical performance of the cemented carbide. These findings contribute to a comprehensive understanding of the contribution of Y to the properties of cemented carbides.
{"title":"Effect of Y₂O₃ content on microstructure, mechanical properties, and corrosion resistance of WC-Co hard alloys prepared by powder metallurgy","authors":"Li Zhiyong , Azman Jalar , Norinsan Kamil Othman","doi":"10.1016/j.ijoes.2024.100922","DOIUrl":"10.1016/j.ijoes.2024.100922","url":null,"abstract":"<div><div>The content of additive Y has a significant impact on the microstructure and mechanical properties of sintered cemented carbides prepared via powder metallurgy. However, the effects of Y content on the properties of cemented carbides remain poorly understood. This study investigates the effect of the content of Y<sub>2</sub>O<sub>3</sub>, introduced via a spray phase transformation process, on the microstructure, mechanical properties, and corrosion resistance of the WC-Co cemented carbide, to advance knowledge in this field. An ultrafine Co-based composite powder containing Y<sub>2</sub>O<sub>3</sub> was synthesised using WC, (CH<sub>3</sub>COO)<sub>2</sub>Co·4 H<sub>2</sub>O, and Y(C<sub>2</sub>H<sub>3</sub>O<sub>2</sub>)<sub>3</sub>·4 H<sub>2</sub>O. The powder was prepared via spray conversion, calcination, oxidation, and low-temperature reduction. The WC-8Co-Y<sub>2</sub>O<sub>3</sub> cemented carbide was fabricated through high-energy ball milling and spark plasma sintering to ensure the uniform distribution of the Co bonding phase. The spray transformation process produced irregular amorphous precursor powders containing Co and Y. After calcination, the powders exhibited a reduction in particle size and underwent agglomeration. The ball milling of the WC-8Co-Y<sub>2</sub>O<sub>3</sub> composite powder with added WC further reduced the particle size and intensified agglomeration. An increase in the Y<sub>2</sub>O<sub>3</sub> content resulted in grain refinement and an increase in the number of WC/Co grain boundaries, thereby improving the corrosion resistance of the alloy. The mechanical properties of the alloys exhibited a trend in which the density, Vickers hardness, and fracture toughness initially increased and then decreased with increasing Y<sub>2</sub>O<sub>3</sub> content. At 1.5 wt% Y<sub>2</sub>O<sub>3</sub>, these properties reached their maximum values, achieving a relative density of 98.94 %, a Vickers hardness of 2034 HV30, and a fracture toughness of 8.39 MPa·m<sup>1/2</sup>. The alloy also exhibited optimal corrosion resistance, with E<sub>corr</sub> and i<sub>corr</sub> values of −252 mV and 6.464 μA/cm<sup>2</sup>, respectively. The presence of Y<sub>2</sub>O<sub>3</sub> promoted the formation of an ultrafine Co phase, which mitigated dislocation motion, thereby enhancing the mechanical performance of the cemented carbide. These findings contribute to a comprehensive understanding of the contribution of Y to the properties of cemented carbides.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 1","pages":"Article 100922"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.ijoes.2024.100874
Paulsamy Raja , Tse-Wei Chen , Shen-Ming Chen , Palraj Kalimuthu , Ganesan Anushya , Rasu Ramachandran , Abdullah G. Al-Sehemi , Vinitha Mariyappan , Saranvignesh Alargarsamy , Mohammed Mujahid Alam , Ajith Velraj , Selvam Selvapriya , Ramanujam Kannan
Human-induced global warming poses one of the most urgent and critical challenges to our planet's atmosphere, ecosystems, and overall well-being. To combat this, we must focus on reducing our reliance on fossil fuels, thereby leading to a consequent decrease in atmospheric CO2 levels. However, the endeavour to curb CO2 emissions is riddled with obstacles, including sluggish kinetic reactions of the CO2 conversion process and poor selectivity of the conventional methods. In addition, detecting CO2 products and intermediates on a small scale presents a notable challenge within this field. The minute quantity of the CO2 product has the potential to undergo further oxidation or evaporation, thereby complicating the detection process. Within the realm of CO2 reduction methods, the photoelectrochemical (PEC) CO2 conversion technique emerges as highly promising and feasible. This method facilitates precise control over the thermodynamics and kinetics of the CO2 reduction process, thereby enabling improved product selectivity and accelerated reaction kinetics. Its emulation of natural photosynthesis with minimal energy input elevates its potential for widespread adoption. Nevertheless, there are certain limitations currently hindering its widespread application. In contrast, in recent years, 2D electrode materials have demonstrated promising results for PEC CO2 conversion. The distinct mechanical, physical, and electrochemical properties of 2D materials hold significant promise as novel catalysts for CO2 reduction. Furthermore, modifying the 2D electrode surface through techniques such as spin-coating, sputter coating, electrophoretic deposition, and electrochemical means can substantially enhance CO2 reduction and facilitate the production of valuable by-products. These 2D-based composite materials present an innovative perspective, encapsulating their performance and the inherent challenges of this pioneering field.
{"title":"Two-dimensional electrode material for (photo)electrochemical reduction of CO2: An overview","authors":"Paulsamy Raja , Tse-Wei Chen , Shen-Ming Chen , Palraj Kalimuthu , Ganesan Anushya , Rasu Ramachandran , Abdullah G. Al-Sehemi , Vinitha Mariyappan , Saranvignesh Alargarsamy , Mohammed Mujahid Alam , Ajith Velraj , Selvam Selvapriya , Ramanujam Kannan","doi":"10.1016/j.ijoes.2024.100874","DOIUrl":"10.1016/j.ijoes.2024.100874","url":null,"abstract":"<div><div>Human-induced global warming poses one of the most urgent and critical challenges to our planet's atmosphere, ecosystems, and overall well-being. To combat this, we must focus on reducing our reliance on fossil fuels, thereby leading to a consequent decrease in atmospheric CO<sub>2</sub> levels. However, the endeavour to curb CO<sub>2</sub> emissions is riddled with obstacles, including sluggish kinetic reactions of the CO<sub>2</sub> conversion process and poor selectivity of the conventional methods. In addition, detecting CO<sub>2</sub> products and intermediates on a small scale presents a notable challenge within this field. The minute quantity of the CO<sub>2</sub> product has the potential to undergo further oxidation or evaporation, thereby complicating the detection process. Within the realm of CO<sub>2</sub> reduction methods, the photoelectrochemical (PEC) CO<sub>2</sub> conversion technique emerges as highly promising and feasible. This method facilitates precise control over the thermodynamics and kinetics of the CO<sub>2</sub> reduction process, thereby enabling improved product selectivity and accelerated reaction kinetics. Its emulation of natural photosynthesis with minimal energy input elevates its potential for widespread adoption. Nevertheless, there are certain limitations currently hindering its widespread application. In contrast, in recent years, 2D electrode materials have demonstrated promising results for PEC CO<sub>2</sub> conversion. The distinct mechanical, physical, and electrochemical properties of 2D materials hold significant promise as novel catalysts for CO<sub>2</sub> reduction. Furthermore, modifying the 2D electrode surface through techniques such as spin-coating, sputter coating, electrophoretic deposition, and electrochemical means can substantially enhance CO<sub>2</sub> reduction and facilitate the production of valuable by-products. These 2D-based composite materials present an innovative perspective, encapsulating their performance and the inherent challenges of this pioneering field.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 1","pages":"Article 100874"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.ijoes.2024.100906
Xiaoping Zhang , Yaya Qin
Cardiovascular diseases remain a critical global health challenge, necessitating advanced diagnostic tools for early detection and monitoring. This review comprehensively examines the emerging field of photoelectrochemical (PEC) sensing strategies for cardiovascular biomarker detection, highlighting recent technological innovations and applications. We analyze various PEC detection mechanisms, including direct label-free approaches and indirect amplification methods, emphasizing their roles in achieving enhanced sensitivity and specificity. The review explores crucial developments in semiconductor nanostructures, composite materials, and two-dimensional materials, detailing their integration into sensing platforms. Particular attention is given to recognition elements, including antibodies and aptamers, and their optimization for specific biomarker detection. Recent advances in signal amplification strategies, such as enzymatic labeling and nanoparticle-based enhancement, are discussed in the context of achieving clinically relevant detection limits. The review also addresses current technical challenges, including matrix effects in biological samples and long-term stability issues, while highlighting promising solutions through materials engineering and device design. Understanding these aspects is crucial for advancing PEC biosensor development toward practical clinical applications.
{"title":"Photoelectrochemical sensing strategies for cardiovascular biomarkers: A review","authors":"Xiaoping Zhang , Yaya Qin","doi":"10.1016/j.ijoes.2024.100906","DOIUrl":"10.1016/j.ijoes.2024.100906","url":null,"abstract":"<div><div>Cardiovascular diseases remain a critical global health challenge, necessitating advanced diagnostic tools for early detection and monitoring. This review comprehensively examines the emerging field of photoelectrochemical (PEC) sensing strategies for cardiovascular biomarker detection, highlighting recent technological innovations and applications. We analyze various PEC detection mechanisms, including direct label-free approaches and indirect amplification methods, emphasizing their roles in achieving enhanced sensitivity and specificity. The review explores crucial developments in semiconductor nanostructures, composite materials, and two-dimensional materials, detailing their integration into sensing platforms. Particular attention is given to recognition elements, including antibodies and aptamers, and their optimization for specific biomarker detection. Recent advances in signal amplification strategies, such as enzymatic labeling and nanoparticle-based enhancement, are discussed in the context of achieving clinically relevant detection limits. The review also addresses current technical challenges, including matrix effects in biological samples and long-term stability issues, while highlighting promising solutions through materials engineering and device design. Understanding these aspects is crucial for advancing PEC biosensor development toward practical clinical applications.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 1","pages":"Article 100906"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.ijoes.2024.100910
Ziqin Tang , Bingbing Wang , Xieeryazidan Aday
This study explores the effect of strain on the corrosion resistance of 304 stainless steel welded joints through electrochemical testing while also presenting a novel pitting model that accounts for the influence of stress and strain on pit growth behavior. Initially, bending experiments and open circuit potential tests were conducted on the welded joints, revealing that compressive stress increases the open circuit potential, while tensile stress decreases it. Subsequently, tensile tests and polarization curve assessments demonstrated that laser oscillating welding enhances both the tensile strength and corrosion resistance of the joints, outperforming traditional laser welding. The measured corrosion potentials were −0.25 V and −0.27 V, shifting to −0.34 V and −0.35 V after the tensile tests. Additionally, finite element simulations based on the Arbitrary Lagrangian-Eulerian method were used to model pitting corrosion propagation. The results indicated that pitting corrosion leads to uneven stress distribution and localized plastic deformation, with its development closely linked to the material's stress state. This results in increased stress as pits grow, consistent with the mechano-electrochemical (M-E) effect.
{"title":"Impact of strain on the corrosion resistance of 304 stainless steel welded joints using electrochemical methods and numerical modeling of stress corrosion","authors":"Ziqin Tang , Bingbing Wang , Xieeryazidan Aday","doi":"10.1016/j.ijoes.2024.100910","DOIUrl":"10.1016/j.ijoes.2024.100910","url":null,"abstract":"<div><div>This study explores the effect of strain on the corrosion resistance of 304 stainless steel welded joints through electrochemical testing while also presenting a novel pitting model that accounts for the influence of stress and strain on pit growth behavior. Initially, bending experiments and open circuit potential tests were conducted on the welded joints, revealing that compressive stress increases the open circuit potential, while tensile stress decreases it. Subsequently, tensile tests and polarization curve assessments demonstrated that laser oscillating welding enhances both the tensile strength and corrosion resistance of the joints, outperforming traditional laser welding. The measured corrosion potentials were −0.25 V and −0.27 V, shifting to −0.34 V and −0.35 V after the tensile tests. Additionally, finite element simulations based on the Arbitrary Lagrangian-Eulerian method were used to model pitting corrosion propagation. The results indicated that pitting corrosion leads to uneven stress distribution and localized plastic deformation, with its development closely linked to the material's stress state. This results in increased stress as pits grow, consistent with the mechano-electrochemical (M-E) effect.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 1","pages":"Article 100910"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.ijoes.2024.100895
Shiwen Zhao, Shu Du
This study presents the development of a molecularly imprinted polymer (MIP) based voltammetric sensor for the ultra-sensitive detection of osimertinib, a third-generation epidermal growth factor receptor tyrosine kinase inhibitor. The sensor was fabricated using a unique thia-bilane (S-BIL) functional monomer, which enhances the binding affinity and selectivity towards osimertinib. The pS-BIL MIP sensor exhibited a wide linear range (0.01–1000 nM), an extremely low detection limit (0.005 nM), and excellent selectivity, demonstrating its superiority over previously reported methods. The imprinting effect was confirmed through various characterization techniques, revealing the formation of specific recognition sites and improved electron transfer properties. The sensor displayed remarkable stability, retaining 95.2 % of its initial response after 30 days, and high reproducibility relative standard deviation (RSD) = 3.2 %, n = 5). Moreover, the pS-BIL MIP sensor was successfully applied to the determination of osimertinib in spiked human serum samples, with recoveries ranging from 96.5 % to 103.2 % and RSDs below 4.5 %. These findings highlight the immense potential of the developed sensor for the sensitive and reliable monitoring of osimertinib in clinical settings.
{"title":"Voltammetric analysis of osimertinib with ultrahigh sensitivity enabled by molecular imprinting technology","authors":"Shiwen Zhao, Shu Du","doi":"10.1016/j.ijoes.2024.100895","DOIUrl":"10.1016/j.ijoes.2024.100895","url":null,"abstract":"<div><div>This study presents the development of a molecularly imprinted polymer (MIP) based voltammetric sensor for the ultra-sensitive detection of osimertinib, a third-generation epidermal growth factor receptor tyrosine kinase inhibitor. The sensor was fabricated using a unique thia-bilane (S-BIL) functional monomer, which enhances the binding affinity and selectivity towards osimertinib. The pS-BIL MIP sensor exhibited a wide linear range (0.01–1000 nM), an extremely low detection limit (0.005 nM), and excellent selectivity, demonstrating its superiority over previously reported methods. The imprinting effect was confirmed through various characterization techniques, revealing the formation of specific recognition sites and improved electron transfer properties. The sensor displayed remarkable stability, retaining 95.2 % of its initial response after 30 days, and high reproducibility relative standard deviation (RSD) = 3.2 %, n = 5). Moreover, the pS-BIL MIP sensor was successfully applied to the determination of osimertinib in spiked human serum samples, with recoveries ranging from 96.5 % to 103.2 % and RSDs below 4.5 %. These findings highlight the immense potential of the developed sensor for the sensitive and reliable monitoring of osimertinib in clinical settings.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 1","pages":"Article 100895"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.ijoes.2024.100884
Xiaoling Yang, Weijuan Zhang, Lan Huang
This study investigates the effects of ultrasonic treatment on the oxygen evolution reaction (OER) performance of polycrystalline nickel electrodes in alkaline media. Both continuous and pulsed ultrasonic treatments were applied, with durations ranging from 15 to 60 minutes. Scanning electron microscopy revealed the formation of a porous surface structure, contributing to a 4.2-fold increase in electrochemically active surface area after 60 minutes of treatment. Linear sweep voltammetry showed a progressive enhancement in OER activity, with the exchange current density increasing from 3.2 × 10−7 A/cm² for the untreated electrode to 2.8 × 10−5A/cm² for the 60-minute treated electrode. Pulsed ultrasound treatment demonstrated superior performance compared to continuous treatment, yielding a lower Tafel slope of 55 mV/dec versus 60 mV/dec. X-ray photoelectron spectroscopy analysis indicated an increase in surface oxides and hydroxides from 18.3 % to 67.5 % after treatment. Rotating disk electrode experiments confirmed improved mass transport properties, with kinetic current densities at 500 mV overpotential increasing from 72.3 mA/cm² to 198.6 mA/cm². High-speed imaging revealed cavitation-induced phenomena during ultrasonic treatment, contributing to the formation of active sites and nanostructuring. These findings demonstrate the potential of ultrasonic treatment, particularly in pulsed mode, as an effective method for enhancing the OER performance of nickel-based electrocatalysts.
{"title":"Enhancing oxygen evolution reaction performance of ultrasonically treated nickel electrodes in alkaline media","authors":"Xiaoling Yang, Weijuan Zhang, Lan Huang","doi":"10.1016/j.ijoes.2024.100884","DOIUrl":"10.1016/j.ijoes.2024.100884","url":null,"abstract":"<div><div>This study investigates the effects of ultrasonic treatment on the oxygen evolution reaction (OER) performance of polycrystalline nickel electrodes in alkaline media. Both continuous and pulsed ultrasonic treatments were applied, with durations ranging from 15 to 60 minutes. Scanning electron microscopy revealed the formation of a porous surface structure, contributing to a 4.2-fold increase in electrochemically active surface area after 60 minutes of treatment. Linear sweep voltammetry showed a progressive enhancement in OER activity, with the exchange current density increasing from 3.2 × 10<sup>−7</sup> A/cm² for the untreated electrode to 2.8 × 10<sup>−5</sup>A/cm² for the 60-minute treated electrode. Pulsed ultrasound treatment demonstrated superior performance compared to continuous treatment, yielding a lower Tafel slope of 55 mV/dec versus 60 mV/dec. X-ray photoelectron spectroscopy analysis indicated an increase in surface oxides and hydroxides from 18.3 % to 67.5 % after treatment. Rotating disk electrode experiments confirmed improved mass transport properties, with kinetic current densities at 500 mV overpotential increasing from 72.3 mA/cm² to 198.6 mA/cm². High-speed imaging revealed cavitation-induced phenomena during ultrasonic treatment, contributing to the formation of active sites and nanostructuring. These findings demonstrate the potential of ultrasonic treatment, particularly in pulsed mode, as an effective method for enhancing the OER performance of nickel-based electrocatalysts.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 1","pages":"Article 100884"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.ijoes.2024.100911
Xu Tang, Peng Qiu, Zhengbing Xia
Ammonia is one of the most important raw materials in human industrial production and agricultural life. At present, the industrial ammonia production process needs to consume a large amount of fossil fuels to obtain a high-temperature and high-pressure reaction environment, which leads to serious environmental pollution caused by the synthetic ammonia industry. Electrocatalytic nitrogen reduction reaction (NRR) uses nitrogen and water resources as raw materials, and uses electricity generated by clean energy to provide power to achieve ammonia synthesis. It is one of the green and environmentally friendly ammonia production methods. However, the electrocatalytic synthesis of ammonia is still difficult to achieve large-scale industrial applications, mainly because the catalyst used in the reaction is difficult to meet the requirements of high activity and high selectivity. In this paper, a catalyst with four N-coordinated Fe atoms on graphene (Fe2N4@G) was designed to study the mechanism of electrocatalytic reduction. Firstly, the stability of Fe2N4@G catalyst at 300 K was studied by ab initio molecular dynamics. Secondly, the adsorption mode of N2 on Fe2N4@G and its hydrogenation reduction reaction were studied. The best reduction mechanism of N2 on Fe2N4@G was an enzymatic mechanism, which was consistent with the natural nitrogenase mechanism. And the free energy of the rate-determining step is only 0.50 eV, indicating that Fe2N4@G has excellent electrocatalytic activity. Finally, the side reaction energy of HER and lattice N atom with NRR is higher than that of NRR, indicating that Fe2N4@G catalyst has good selectivity and stability. This paper provides new insights into the design and preparation of diatomic catalysts for NRR.
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