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Aetiology of Convulsions in Relation to Clinical, Electrophysiological and Radiological Changes and Management 惊厥的病因与临床、电生理和放射学的变化及处理
Pub Date : 2019-11-01 DOI: 10.21276/ijcmr.2019.6.11.34
B. Ramulu
Introducion: An epileptic seizure may be conceptualized as a paroxysmal pathological process in the brain of a heterogeneous etiology with heteromorphic clinical and electrophysiological manifestation. Current research aimed to study the aetiology of convulsions in relation to clinical, electrophysiological and radiological changes and management. Material and methods: It was a prospective study carried out on 50 patients of convulsions admitted in the medical wards. Patients with convulsions of all age groups were included in this study. Results: The incidence of convulsions in those people below 18 years of age was 30% and in adults above 50 years of age was 30%. The incidence is not in confirmation with porter’s studies where it is highest above 80% in the children below 18 years age. Most common etiology in study was cerebrovascular accidents 13(26%) and followed by infraction in 10 cases(20%). Incidence of seizure was more in males than compared to females. Most of the patients with seizures were presented with generalised tonic clonic seizures(20 cases). Conclusion: Focal seizures were more commoner than other groups of seizures. 20% of patients in this study remained undiagnosed with obscure aetiology. Keyword: Aetiology of Convulsions, Relation to Clinical, Electrophysiological and Radiological
简介:癫痫发作可被定义为脑内具有异质病因、异型临床和电生理表现的阵发性病理过程。目前的研究旨在研究抽搐的病因与临床,电生理和放射学的变化和处理。材料与方法:对50例住院的惊厥患者进行前瞻性研究。所有年龄组的惊厥患者均纳入本研究。结果:18岁以下惊厥发生率为30%,50岁以上惊厥发生率为30%。波特的研究没有证实发病率在18岁以下儿童中最高,超过80%。研究中最常见的病因是脑血管意外13例(26%),其次是梗死10例(20%)。男性癫痫发作的发生率高于女性。20例患者以全身性强直性阵挛性发作为主。结论:局灶性癫痫发生率高于其他组。本研究中有20%的患者未确诊,病因不明。关键词:惊厥病因,与临床、电生理、放射学的关系
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引用次数: 0
Electronic Nicotine Delivery Systems (ENDS): Smoking Cessation Tools or Escalating Nicotine Addiction 电子尼古丁输送系统(ENDS):戒烟工具或升级尼古丁成瘾
Pub Date : 2019-11-01 DOI: 10.21276/ijcmr.2019.6.11.8
S. Vardhan, M. Bajpai, Rigvardhan Rigvardhan
Introduction: Electronic nicotine delivery systems (ENDS) are used to smoke or ‘vape’, a flavoured solution containing nicotine, an addictive chemical found in cigarettes and tobacco products. Contrary to popular belief that they are useful as smoking cessation tools, current data does not support this theory. In fact, they cause various deleterious effects in body including death. Their use has seen exponential rise amongst youth. We conducted a study in northern India to assess its prevalent use and awareness amongst youth. Material and methods: A questionnaire with various questions related to ENDS was circulated amongst higher secondary schools and university students to ascertain their use and awareness amongst students regarding its usage pattern and health effects. After receiving first 200 confirmed responses of use, the data was analysed. Results: First 200 confirmed users were obtained after 764 responses. 82% were exposed to ENDS at an age of 1520 years. 38% said vaping was ‘COOL’ and 32% started it because of nice flavours. 28% believed that ENDS are safe and 47% were either not sure or not aware. 41% were now more open to the idea of regular smoking. Conclusion: Nicotine is one of the most addictive drug and exposure of youth to ENDS predisposes them to nicotine at an early age. Understanding of the potential harmful effects of ENDS is not fully comprehended by them predisposing them to addiction. Therefore, the ban on ENDS by the government is justified.
电子尼古丁输送系统(ENDS)用于吸烟或“vape”,这是一种含有尼古丁的调味溶液,尼古丁是香烟和烟草制品中发现的一种令人上瘾的化学物质。与人们普遍认为它们是有用的戒烟工具相反,目前的数据并不支持这一理论。事实上,它们会对身体造成包括死亡在内的各种有害影响。他们的使用在年轻人中呈指数增长。我们在印度北部进行了一项研究,以评估其在年轻人中的普遍使用和意识。材料和方法:在高中和大学生中分发了一份带有各种问题的调查问卷,以确定其使用情况以及学生对其使用模式和健康影响的认识。在收到前200个确认的使用回复后,对数据进行分析。结果:在764次回复后,获得了前200名确认用户。82%的人在1520岁时接触过ENDS。38%的人说电子烟很“酷”,32%的人开始吸电子烟是因为它的味道很好。28%的人认为ENDS是安全的,47%的人不确定或不知道。41%的人现在更愿意接受经常吸烟的想法。结论:尼古丁是最容易上瘾的药物之一,青少年接触ENDS会使他们在幼年时就易染上尼古丁。对ENDS的潜在有害影响的理解并没有完全理解,它们使它们容易上瘾。因此,政府对ENDS的禁令是合理的。
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引用次数: 0
A Prospective Study of Clinical Profile, Predisposing Factors and Management of Deep Venous Thrombosis 深静脉血栓形成的临床特点、易感因素及治疗的前瞻性研究
Pub Date : 2019-11-01 DOI: 10.21276/ijcmr.2019.6.11.40
P. Naresh, Jangra Amit, Kumar Virender, K. Ritesh
Introduction: Deep venous thrombosis (DVT) of lower limbs is one of the most common cause for the majority of deaths caused by pulmonary embolism. Deep vein thrombosis is the formation of blood clots in the deep veins which commonly affects the leg veins such as the calf veins, femoral vein, or popliteal vein or veins of the pelvis. The aim of the study was to evaluate clinical profile of patients in form of age, sex, etiological factors of deep venous thrombosis in our institute. Also study risk the factors in patients of deep venous thrombosis. Material and Methods: Study was a prospective study which was conducted on 108 symptomatic patients of deep vein thrombosis which were proved by colour doppler ultrasonography. All patients who were more than 18 years of age and either sex were taken into study. Results: In our study 37.03% of the patients were males and 62,97% were females with majority belonging to 2130 years of age group (33.82%). In this study the youngest patient was 20 years old female and the oldest patient was 96 years old female. Male: Female ratio was 1:1.7. The least common age group affected is extreme of age i.e. ≥ 20 years and > 60 years of age in both sexes. The most common limb affected is left lower limb 62 patients (57.40) and right limb involvement is seen in 39.81% of patients. Bilateral lower limb DVT is present in two patients and one patient was upper limb DVT. Predisposing factors associated with thrombosis in deep veins maximally seen in 46 patients in 42.59% due to unknown cause. Pregnancy and post-partum was the second most common predisposing factor associated with DVT which is seen in 33 patients in 30.55%. Thrombosis due to orthopaedic trauma is seen eight patients only. Chronic illness and malignancy was present in 19.44% of patients. Conclusion: It is very important for accurate diagnosis of DVT to prevent potentially fatal complications like pulmonary embolism (PE) and pulmonary hypertension. Also it is very important to avoid anticoagulants therapy with associated risk of bleeding in patients of misdiagnosed and negative colour doppler findings. Because clinical features are nonspecific; hence new strategies were evolved for diagnosing this condition.
下肢深静脉血栓形成(DVT)是肺栓塞引起的大多数死亡的最常见原因之一。深静脉血栓是在深静脉中形成血块,通常影响小腿静脉,如小腿静脉、股静脉、腘静脉或骨盆静脉。本研究的目的是评估我院深静脉血栓形成患者的年龄、性别、病因等临床特征。同时研究深静脉血栓形成的危险因素。材料与方法:对108例经彩色多普勒超声证实的有症状的深静脉血栓患者进行前瞻性研究。所有18岁以上的患者,无论男女,都被纳入研究。结果:本组患者中男性占37.03%,女性占62.97%,以2130岁年龄组居多(33.82%)。本研究中年龄最小的患者为20岁的女性,年龄最大的患者为96岁的女性。男女比例为1:7 .7。受影响最不常见的年龄组是极端年龄,即≥20岁和> 60岁的男女。最常见的受累肢体为左下肢62例(57.40),右肢受累39.81%。2例患者双侧下肢深静脉血栓形成,1例患者上肢深静脉血栓形成。深静脉血栓形成的易感因素最多见于46例,占42.59%,原因不明。妊娠和产后是第二个最常见的诱发DVT的因素,在33例患者中出现,占30.55%。骨科创伤致血栓形成病例仅有8例。19.44%的患者存在慢性疾病和恶性肿瘤。结论:准确诊断深静脉血栓对预防肺栓塞、肺动脉高压等可能致死性并发症具有重要意义。此外,对于误诊和彩色多普勒阴性的患者,避免抗凝治疗伴有出血风险也是非常重要的。因为临床特征是非特异性的;因此出现了诊断这种疾病的新策略。
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引用次数: 0
Comparative Study of Dry Eye after Phacoemulsification and Manual SICS in Tertiary Centre of Jharkhand 贾坎德邦三级中心超声乳化术与手工超声乳化术后干眼的比较研究
Pub Date : 2019-11-01 DOI: 10.21276/ijcmr.2019.6.11.24
P. Kumari, M. D. Lakra
Introduction: Cataract is the major cause of blindness in the developing world. Study aimed at evaluation of tear film stability and tear secretion after phacoemulsification compared with MSICS. Material and methods: This prospective comparative randomized study was performed in a tertiary centre of Jharkhand between June 2018 to March 2019. 187 patients with senile cataract were included in this study. Group A had 110 patients undergoing MSICS and group B 77 patients undergoing phacoemulsification. Dry eye symptoms(DES) characterizedby redness, burning, stinging, foreign body sensation, photophobia. Corneal fluorescein staining was performed. Basal Schirmer test was performed for assessment of aqueous tear production. Patients were examined post operatively on 1st week, 4th week and 3rd month. Results: Out of 187 patients 103(55.08%) were male and 84(44.91%) were female. Grade of DES increased significantly 1 week after each procedure compared to pre-operative data and remained increased after 4 weeks of surgery. After 3 months the symptoms decreased and returned to baseline data. Conclusion: MSICS is as effective as phacoemulsification with no difference between both techniques regarding tear film stability and tear secretion.
白内障是发展中国家致盲的主要原因。研究目的是评价超声乳化术后泪液膜稳定性和泪液分泌情况。材料和方法:这项前瞻性比较随机研究于2018年6月至2019年3月在贾坎德邦的一个三级中心进行。本研究纳入了187例老年性白内障患者。A组110例行mscs, B组77例行超声乳化术。干眼症状(DES)以发红、灼烧、刺痛、异物感、畏光为特征。角膜荧光素染色。基底Schirmer试验用于评估含水泪液的产生。术后第1周、第4周、第3个月复查。结果:187例患者中,男性103例(55.08%),女性84例(44.91%)。与术前相比,每次手术后1周DES评分显著上升,4周后仍保持上升。3个月后症状减轻并恢复到基线数据。结论:超声乳化术与超声乳化术在泪膜稳定性和泪液分泌方面无明显差异。
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引用次数: 1
Study on Awareness and Assessment of Diabetic Retinopathy in Diabetic Patients Attending Ophthalmology Clinic at a Tertiary Care Hospital, Telangana State 泰伦加纳邦三级医院眼科门诊糖尿病患者对糖尿病视网膜病变的认知和评估研究
Pub Date : 2019-11-01 DOI: 10.21276/ijcmr.2019.6.11.39
Chintala Narsaiah, P. Manoj, A. Raju
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引用次数: 11
Endoscopic Transnasal Repair of Bilateral Choanal Atresia in Neonates: Our Experience 经鼻内镜治疗新生儿双侧后肛门闭锁的经验
Pub Date : 2019-11-01 DOI: 10.21276/ijcmr.2019.6.11.36
M. Navalakhe, S. Chhabria, N. Gaikwad, Vivek Dwivedi
Introduction: Congenital choanal atresia is the developmental failure of the nasal cavity to communicate with nasopharynx. The newborn baby presents with intermittent attacks of cyanosis and respiratory distress soon after birth. Inability to pass nasal catheters in both the nares reveals the diagnosis of bilateral Choanal Atresia. Study aimed to present our experience with a endoscopic approach for transnasal repair of choanal atresia. Material and Methods: Seven patients with mean age 7 days with bilateral choanal atresia,underwent endoscopic repair using a mucoperichondrial flap from the nasal septum. The bony stenosis was opened with a surgical curette or drill, and the raw surface was covered by the flap. Results: A total of 7 choanae were operated. With mean follow-up 27 months. Out of seven patients operated by us, five patient survived with a patent choana.We had two deaths, one patient expired during the procedure due to bleeding and one patient expired three hour after the procedure due to CCF. Conclusion: Endoscopic repair of choanal atresia is a safe and
简介:先天性后鼻孔闭锁是一种鼻腔发育障碍,无法与鼻咽沟通。新生儿出生后不久出现间歇性发绀和呼吸窘迫。双侧鼻腔不能通过鼻导管提示双侧后肛门闭锁。研究的目的是介绍我们的经验,内窥镜入路经鼻修复后肛门闭锁。材料与方法:7例平均年龄为7天的双侧后肛门闭锁患者,采用鼻中隔粘骨膜瓣进行内镜修复。用手术刮匙或钻打开骨狭窄,皮瓣覆盖原表面。结果:共手术7例。平均随访27个月。在接受手术的7名患者中,有5名患者存活下来,并留下了未愈合的咽喉。我们有两名患者死亡,一名患者在手术中因出血而死亡,另一名患者在手术后三小时因CCF而死亡。结论:内镜下修复后肛门闭锁是一种安全、有效的手术方法
{"title":"Endoscopic Transnasal Repair of Bilateral Choanal Atresia in Neonates: Our Experience","authors":"M. Navalakhe, S. Chhabria, N. Gaikwad, Vivek Dwivedi","doi":"10.21276/ijcmr.2019.6.11.36","DOIUrl":"https://doi.org/10.21276/ijcmr.2019.6.11.36","url":null,"abstract":"Introduction: Congenital choanal atresia is the developmental failure of the nasal cavity to communicate with nasopharynx. The newborn baby presents with intermittent attacks of cyanosis and respiratory distress soon after birth. Inability to pass nasal catheters in both the nares reveals the diagnosis of bilateral Choanal Atresia. Study aimed to present our experience with a endoscopic approach for transnasal repair of choanal atresia. Material and Methods: Seven patients with mean age 7 days with bilateral choanal atresia,underwent endoscopic repair using a mucoperichondrial flap from the nasal septum. The bony stenosis was opened with a surgical curette or drill, and the raw surface was covered by the flap. Results: A total of 7 choanae were operated. With mean follow-up 27 months. Out of seven patients operated by us, five patient survived with a patent choana.We had two deaths, one patient expired during the procedure due to bleeding and one patient expired three hour after the procedure due to CCF. Conclusion: Endoscopic repair of choanal atresia is a safe and","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81731643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Gingival Depigmentation along with Frenectomy and Diastema Closure - A Case Report 牙龈色素脱色伴系带切除及隔膜关闭1例报告
Pub Date : 2019-11-01 DOI: 10.21276/ijcmr.2019.6.11.33
S. Verma, J. Thakur, B. Kumar, N. Sharma
Introduction: Dental aesthetic plays an important role in overall facial representation of a person. A smile enhances expression of a person. A perfect harmony of size, form, and po sition of the teeth and their relation with alveolar bone and gingival tissue have important role in creating a pleasing smile. Excessive gingival melanin pigmentation can give brownish to blackish colour to gingival. Case report: This case report highlights a case of hyperpigmentation gingiva with midline diastema which was treated by gingival depigmentation using the scalpel technique with frenectomy and cosmetic filling. Conclusion: The appearance of ‘black gum’ especially in high smile line person gives unaesthetic smile. The demand for cosmetic therapy is commonly in people with pigmented
口腔美学在一个人的整体面部表现中起着重要的作用。微笑可以增强一个人的表现力。牙齿的大小、形状和位置的完美协调,以及它们与牙槽骨和牙龈组织的关系,对创造一个令人愉快的微笑起着重要的作用。过多的牙龈黑色素会使牙龈呈褐色或黑色。病例报告:本病例报告强调了一个病例的色素沉着牙龈与中线膈,这是治疗牙龈色素沉着使用手术刀技术与美容填充系带切除术。结论:“黑胶”的出现,尤其是在高笑线人群中,会造成不美观的微笑。对美容治疗的需求通常出现在色素沉着的人群中
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引用次数: 1
Prevalence of Eustachian Tube Dysfunction in Adenotonsillitis Patients 腺扁桃体炎患者咽鼓管功能障碍的患病率
Pub Date : 2019-11-01 DOI: 10.21276/ijcmr.2019.6.11.29
M. Coelho, K. Shoba
{"title":"Prevalence of Eustachian Tube Dysfunction in Adenotonsillitis Patients","authors":"M. Coelho, K. Shoba","doi":"10.21276/ijcmr.2019.6.11.29","DOIUrl":"https://doi.org/10.21276/ijcmr.2019.6.11.29","url":null,"abstract":"","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83590038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metronidazole Induced Cerebellar Ataxia: A Rare Case Report 甲硝唑致小脑性共济失调1例
Pub Date : 2019-11-01 DOI: 10.21276/ijcmr.2019.6.11.27
K DhanyaAlva, S. Rai
Introduction: Metronidazole is an antibiotic and an antiprotozoal drug very commonly used in our day to day practice. It is either used alone or in combination with other drugs to treat Pelvic inflammatory disease, Endocarditis and Bacterial Vaginosis. It is generally well tolerated and common side effects include nausea, vomiting, abdominal cramps, metallic taste. Case report: We are presenting a rare case of Metronidazole induced cerebellar ataxia in a patient who received the drug for a relatively shorter duration. Conclusion: The neurological features usually occur when the drug dose exceeds 2g/day for a prolonged period. Peripheral neuropathy, dizziness, encephalopathy, seizures, optic neuropathy can be seen. Cerebellar ataxia is a rare and serious side effect of this drug.
简介:甲硝唑是一种抗生素和抗原虫药物,在我们的日常实践中非常常用。它既可以单独使用,也可以与其他药物联合使用,用于治疗盆腔炎、心内膜炎和细菌性阴道病。通常耐受性良好,常见的副作用包括恶心,呕吐,腹部痉挛,金属味。病例报告:我们提出一个罕见的病例甲硝唑诱导小脑共济失调的病人谁接受了药物相对较短的时间。结论:长时间用药剂量超过2g/d,可出现神经学特征。周围神经病变,头晕,脑病,癫痫发作,视神经病变可见。小脑性共济失调是该药的一种罕见而严重的副作用。
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引用次数: 0
Myroides: An Emerging Pathogen Causing Urinary Tract Infections in Hospitalized Patients 幽门螺杆菌:一种引起住院患者尿路感染的新兴病原体
Pub Date : 2019-11-01 DOI: 10.21276/ijcmr.2019.6.11.28
M. Agrawal, V. Mamoria, Sonali Mittal, Ayushi Sharma
Introduction: The genus Myroides comprises of Gramnegative, non-motile, and nonfermenting bacteria. It is a rare opportunistic pathogen but many recent case reports, however, underscore the pathogenic potential that Myroides spp. possesses for humans. Immunocompromised patients are at higher risk for Myroides infection. Diabetes, catheterization and ICU stay may increase the chances of acquiring Myroides infection. Material and Methods: Urine specimens collected from inpatients were cultured as per standards. Myroides spp. were identified and sensitivity was performed on VITEK® 2 CompactTM. Results: A total of 16 Myroides spp. isolates were obtained in the study period. All the isolates were from catheterized patients residing in intensive care units. Eleven (69%) patients were suffering from diabetes mellitus. Extensive resistance was seen in antibiotic sensitivity results. Minocycline was 100% sensitive. Conclusion: Myroides spp. should be considered among pathogens in hospitalized, catheterized patients. They could be extremely drug resistant. Minocycline is a useful antibiotic while treating UTI caused by Myroides spp.
简介:Myroides属由革兰氏阴性,非运动和非发酵细菌组成。这是一种罕见的机会性病原体,但最近的许多病例报告强调了Myroides对人类具有致病潜力。免疫功能低下的患者有较高的Myroides感染风险。糖尿病、导尿和ICU住院可能会增加Myroides感染的机会。材料与方法:收集住院患者尿液标本,按标准进行培养。鉴定Myroides属,并在VITEK®2 CompactTM上进行灵敏度测定。结果:研究期间共分离得到16株荚膜菌。所有分离株均来自重症监护病房插管患者。11例(69%)患者患有糖尿病。抗生素敏感性结果显示广泛耐药。米诺环素100%敏感。结论:住院留置病人的病原菌中应考虑有乳杆菌属。它们可能具有极强的抗药性。米诺环素是一种有效的抗生素,可用于治疗由米诺环菌引起的尿路感染。
{"title":"Myroides: An Emerging Pathogen Causing Urinary Tract Infections in Hospitalized Patients","authors":"M. Agrawal, V. Mamoria, Sonali Mittal, Ayushi Sharma","doi":"10.21276/ijcmr.2019.6.11.28","DOIUrl":"https://doi.org/10.21276/ijcmr.2019.6.11.28","url":null,"abstract":"Introduction: The genus Myroides comprises of Gramnegative, non-motile, and nonfermenting bacteria. It is a rare opportunistic pathogen but many recent case reports, however, underscore the pathogenic potential that Myroides spp. possesses for humans. Immunocompromised patients are at higher risk for Myroides infection. Diabetes, catheterization and ICU stay may increase the chances of acquiring Myroides infection. Material and Methods: Urine specimens collected from inpatients were cultured as per standards. Myroides spp. were identified and sensitivity was performed on VITEK® 2 CompactTM. Results: A total of 16 Myroides spp. isolates were obtained in the study period. All the isolates were from catheterized patients residing in intensive care units. Eleven (69%) patients were suffering from diabetes mellitus. Extensive resistance was seen in antibiotic sensitivity results. Minocycline was 100% sensitive. Conclusion: Myroides spp. should be considered among pathogens in hospitalized, catheterized patients. They could be extremely drug resistant. Minocycline is a useful antibiotic while treating UTI caused by Myroides spp.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"39 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72587581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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International Journal of Contemporary Medical Research [IJCMR]
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