Pub Date : 2019-11-01DOI: 10.21276/ijcmr.2019.6.11.4
J. Kishore, Avanindra Kumar
{"title":"Prevalence of Dental Anomalies in School Children of Muzaffarpur District (Age 5 to 12 Years)","authors":"J. Kishore, Avanindra Kumar","doi":"10.21276/ijcmr.2019.6.11.4","DOIUrl":"https://doi.org/10.21276/ijcmr.2019.6.11.4","url":null,"abstract":"","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79253976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.21276/ijcmr.2019.6.11.9
P. Gupta, K. Manocha
Introduction: Because the prevalence of antibiotic resistance markedly increases with time worldwide, anti-H. pylori treatment is continuing to be a great challenge for physicians in clinical practice. Eradication of H. pylori infection markedly changes the natural history of peptic ulcer in patients with duodenal or gastric ulcer. Most peptic ulcers associated with H. pylori infection are curable. Aim of present study was to study the efficacies of 14 days ‘ Reverse Hybrid Therapy’ in H.pylori positive G.I.patients. Material and methods: 100 H.pylori positive patients with upper G.I. complaints who underwent upper GI endoscopy were included in the study. H.pylori infection was documented by at least 2 positive results of Rapid Urease Test. Subjects with any of the following criteria were excluded from the study. 1. Previous eradication therapy 2. Allergy to any antibiotic used in study. 3. Coexistence of any serious illness. 4. Pregnancy or lactating women 5. Previous gastrectomy 6. Use of antibiotics within last 4 week. Detailed medical history and demographic details of the patients were recorded. Routine haematogical tests and USG was done. Patients were given 14 days dual therapy ie quadruple regimen (proton pump inhibitor + amoxicillin + clarithromycin + metronidazole) for first 7 days followed by dual regimen of PPI+ amoxicillin for next 7 days. Patients were asked to report at 7, 14 days and at 6 weeks interval. Results: Out of 97 patients 93 patients became negative for H.pylori after 6 week of Reverse Hybrid eradication therapy. It was observed that majority of patients enrolled in the study were in the age group of 41–60 years (50%) followed by below 40 yrs (27%), above 60 yrs (23%). Out of them, 74% were male and 26% were female. Conclusion: Out of 97 patients 93 patients became negative for H.pylori after 6 week of Reverse Hybrid eradication therapy. Hence, Reverse Hybrid Therapy is equally potent therapy to Bismuth based therapy though the latter has a lot of side effects.
{"title":"Efficacies of Reverse Hybrid Therapy in Eradication of Helicobacter pylori Infection","authors":"P. Gupta, K. Manocha","doi":"10.21276/ijcmr.2019.6.11.9","DOIUrl":"https://doi.org/10.21276/ijcmr.2019.6.11.9","url":null,"abstract":"Introduction: Because the prevalence of antibiotic resistance markedly increases with time worldwide, anti-H. pylori treatment is continuing to be a great challenge for physicians in clinical practice. Eradication of H. pylori infection markedly changes the natural history of peptic ulcer in patients with duodenal or gastric ulcer. Most peptic ulcers associated with H. pylori infection are curable. Aim of present study was to study the efficacies of 14 days ‘ Reverse Hybrid Therapy’ in H.pylori positive G.I.patients. Material and methods: 100 H.pylori positive patients with upper G.I. complaints who underwent upper GI endoscopy were included in the study. H.pylori infection was documented by at least 2 positive results of Rapid Urease Test. Subjects with any of the following criteria were excluded from the study. 1. Previous eradication therapy 2. Allergy to any antibiotic used in study. 3. Coexistence of any serious illness. 4. Pregnancy or lactating women 5. Previous gastrectomy 6. Use of antibiotics within last 4 week. Detailed medical history and demographic details of the patients were recorded. Routine haematogical tests and USG was done. Patients were given 14 days dual therapy ie quadruple regimen (proton pump inhibitor + amoxicillin + clarithromycin + metronidazole) for first 7 days followed by dual regimen of PPI+ amoxicillin for next 7 days. Patients were asked to report at 7, 14 days and at 6 weeks interval. Results: Out of 97 patients 93 patients became negative for H.pylori after 6 week of Reverse Hybrid eradication therapy. It was observed that majority of patients enrolled in the study were in the age group of 41–60 years (50%) followed by below 40 yrs (27%), above 60 yrs (23%). Out of them, 74% were male and 26% were female. Conclusion: Out of 97 patients 93 patients became negative for H.pylori after 6 week of Reverse Hybrid eradication therapy. Hence, Reverse Hybrid Therapy is equally potent therapy to Bismuth based therapy though the latter has a lot of side effects.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81013878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.21276/ijcmr.2019.6.11.20
Virgin Joena, R. AnandaXavierPragasam
Introduction: Even after the discovery of vaccines for dengue fever, it remains a major public health problem in developing tropical and subtropical countries, especially in India. The dengue fever has a varied clinical spectrum ranging from a mild headache to severe organ impairment or bleeding, depending on the virulence and susceptibility of the individual. The current study investigated the clinical profile of laboratoryconfirmed dengue patients. A secondary objective was to find the role of haematological parameters in prognosis. Material and Methods: This was a retrospective study conducted in a tertiary care hospital at Madurai following a dengue fever outbreak between August 2017 to November 2017 among laboratory-confirmed dengue patients older than 16 years. All the relevant clinical and laboratory investigation details of the patients were obtained from the medical records of the hospital. Results: Fever was present in all the cases with an average duration of 4.86 ± 1.59 days followed by myalgia (57.39%), vomiting (46.96%), headache (30.43%) and abdominal pain (20%). Bleeding and hepatic complication was presented by 22.16% and 50.43%. The mean platelet recovery duration was 8.42 ± 1.74 days. A strong positive correlation between day of recovery (increasing trend of platelet) from the onset of fever and WBC recovery (rs value: 0.0.713, P value: <0.001) was observed. Conclusion: Dengue fever patients have varied clinical features varying from fever to severe hepatic complication. For assessing the prognosis of dengue fever, along with the continuous monitoring of clinical profile and platelet count, evaluation of WBC recovery is also recommended.
{"title":"Clinical Profile and Role of Haematological Parameters in the Prognosis of Dengue Fever Patients Admitted in a Tertiary Hospital","authors":"Virgin Joena, R. AnandaXavierPragasam","doi":"10.21276/ijcmr.2019.6.11.20","DOIUrl":"https://doi.org/10.21276/ijcmr.2019.6.11.20","url":null,"abstract":"Introduction: Even after the discovery of vaccines for dengue fever, it remains a major public health problem in developing tropical and subtropical countries, especially in India. The dengue fever has a varied clinical spectrum ranging from a mild headache to severe organ impairment or bleeding, depending on the virulence and susceptibility of the individual. The current study investigated the clinical profile of laboratoryconfirmed dengue patients. A secondary objective was to find the role of haematological parameters in prognosis. Material and Methods: This was a retrospective study conducted in a tertiary care hospital at Madurai following a dengue fever outbreak between August 2017 to November 2017 among laboratory-confirmed dengue patients older than 16 years. All the relevant clinical and laboratory investigation details of the patients were obtained from the medical records of the hospital. Results: Fever was present in all the cases with an average duration of 4.86 ± 1.59 days followed by myalgia (57.39%), vomiting (46.96%), headache (30.43%) and abdominal pain (20%). Bleeding and hepatic complication was presented by 22.16% and 50.43%. The mean platelet recovery duration was 8.42 ± 1.74 days. A strong positive correlation between day of recovery (increasing trend of platelet) from the onset of fever and WBC recovery (rs value: 0.0.713, P value: <0.001) was observed. Conclusion: Dengue fever patients have varied clinical features varying from fever to severe hepatic complication. For assessing the prognosis of dengue fever, along with the continuous monitoring of clinical profile and platelet count, evaluation of WBC recovery is also recommended.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83828729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.21276/ijcmr.2019.6.11.43
Nafila A.K
Introduction: Vaccines are one of most successful health interventions that bring about significant reduction in infectious diseases and adverse health consequences. In India, The Expanded Program on Immunization (EPI) was launched in 1978 and it was re-designated as the Universal Immunization program (UIP) in 1985, with a goal to cover at least 85% of infants. In India 7.4 million children are not immunized. Study aimed to determine the knowledge, attitude and practice of mothers with under five children about immunization. Material and methods: Research was conducted to determine the knowledge attitude and practice of mothers with underfive children about immunization. A cross sectional study was conducted among mothers having children aged more than two and half years in the field practice area of K.S. Hegde Medical Academy. Data was collected using a pre-tested semi structured questionnaire from 348 mothers during a period of two months. Among the study participants (92) 26% were from urban area and (256) 74% were from rural area. Mothers were the main decision makers regarding vaccination of the child in both urban and rural areas. Results: Majority 99% supported vaccination. Majority 97% of the mothers in both the urban and rural areas believed that vaccines were protective. In the study it was seen that 93% of the mothers had vaccinated their children as per vaccination card and the rest of the mothers were not up to date with vaccinating their children. Only 43%of the mothers were aware of the side effects and 32% knew about contraindications. In this study it was found that 32% of the mothers believed that vaccination could be done even if the child had fever. Only 22% of the mothers were aware of the SMS notification program by the government. Conclusion: In the study the reasons stated by the mothers for not fully vaccinating the child were because of the side effects 44%, difficulty in reaching the center 28% and long crowds 19%.According to our study, majority of the mothers were supportive of immunizing their children but unaware of their contraindications and side effects.
{"title":"Knowledge Attitude and Practice of Mothers with Under-Five Children about Immunization","authors":"Nafila A.K","doi":"10.21276/ijcmr.2019.6.11.43","DOIUrl":"https://doi.org/10.21276/ijcmr.2019.6.11.43","url":null,"abstract":"Introduction: Vaccines are one of most successful health interventions that bring about significant reduction in infectious diseases and adverse health consequences. In India, The Expanded Program on Immunization (EPI) was launched in 1978 and it was re-designated as the Universal Immunization program (UIP) in 1985, with a goal to cover at least 85% of infants. In India 7.4 million children are not immunized. Study aimed to determine the knowledge, attitude and practice of mothers with under five children about immunization. Material and methods: Research was conducted to determine the knowledge attitude and practice of mothers with underfive children about immunization. A cross sectional study was conducted among mothers having children aged more than two and half years in the field practice area of K.S. Hegde Medical Academy. Data was collected using a pre-tested semi structured questionnaire from 348 mothers during a period of two months. Among the study participants (92) 26% were from urban area and (256) 74% were from rural area. Mothers were the main decision makers regarding vaccination of the child in both urban and rural areas. Results: Majority 99% supported vaccination. Majority 97% of the mothers in both the urban and rural areas believed that vaccines were protective. In the study it was seen that 93% of the mothers had vaccinated their children as per vaccination card and the rest of the mothers were not up to date with vaccinating their children. Only 43%of the mothers were aware of the side effects and 32% knew about contraindications. In this study it was found that 32% of the mothers believed that vaccination could be done even if the child had fever. Only 22% of the mothers were aware of the SMS notification program by the government. Conclusion: In the study the reasons stated by the mothers for not fully vaccinating the child were because of the side effects 44%, difficulty in reaching the center 28% and long crowds 19%.According to our study, majority of the mothers were supportive of immunizing their children but unaware of their contraindications and side effects.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"308 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77057622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.21276/ijcmr.2019.6.11.2
S. Saloni, Navjot Kaur Bajwa Saloni
Introduction: In patients with cirrhosis, albumin synthesis is decreased because of the loss of hepatic cell mass. Adrenal insufficiency (AI) has been demonstrated in patients with severe liver disease. The percentage of AI in cirrhotic patients varies among different studies and depends on different methods and criteria used to evaluate adrenal function. As both serum albumin and cortisol levels are low in cirrhotic patients we want to determine relationship between serum albumin and cortisol levels. Current research aimed to study adrenal insufficiency in patients of cirrhosis and to determine the relationship between serum albumin and serum cortisol levels. Material and Methods: Prospective study was done on 50 patients of cirrhosis who were admitted in medicine/ gastroenterology ward of DMC & H, Ludhiana. Depending on the levels of cortisol, patients were categorized into 3 groups. Clinically diagnosed patients of cirrhosis were included in our study whereas HIV/Immunodeficiency, Severe chronic heart disease, Chronic obstructive lung disease, Chronic hemodialysis, Severe sepsis, septic shock and patients on steroid therapy were excluded. Results: The data was analyzed using Microsoft excel and SPSS version 20.0 (IBM SPSS, Chicago, Illinois). Mean and standard deviation were computed for the variables. The comparison between groups were done by Chi square and ANOVA. AI was present in 14 (28%) patients of Cirrhosis. The difference between cortisol levels with respect to Albumin was found to be statistically significant (0.05). Conclusion: AI forms important part of spectrum of Cirrhosis and these patients should be evaluated for adrenal dysfunction.
在肝硬化患者中，由于肝细胞团块的损失，白蛋白合成减少。肾上腺功能不全(AI)已在严重肝病患者中得到证实。肝硬化患者中AI的百分比在不同的研究中有所不同，这取决于用于评估肾上腺功能的不同方法和标准。由于肝硬化患者的血清白蛋白和皮质醇水平都很低，我们想确定血清白蛋白和皮质醇水平之间的关系。目前的研究旨在研究肝硬化患者的肾上腺功能不全，并确定血清白蛋白和血清皮质醇水平之间的关系。材料与方法:对卢迪亚纳DMC & H医院内科/消化内科病房收治的50例肝硬化患者进行前瞻性研究。根据皮质醇水平，患者被分为三组。临床诊断为肝硬化的患者被纳入我们的研究，而HIV/免疫缺陷、严重慢性心脏病、慢性阻塞性肺病、慢性血液透析、严重败血症、感染性休克和接受类固醇治疗的患者被排除在外。结果:采用Microsoft excel和SPSS version 20.0 (IBM SPSS, Chicago, Illinois)对数据进行分析。计算变量的均值和标准差。组间比较采用卡方分析和方差分析。14例(28%)肝硬化患者存在AI。皮质醇水平与白蛋白水平的差异有统计学意义(0.05)。结论:AI是肝硬化谱的重要组成部分，应对其肾上腺功能障碍进行评估。
{"title":"To Study Adrenal Insufficiency and to Determine Relationship between Serum Albumin and Serum Cortisol Levels in Cirrhotic Patients","authors":"S. Saloni, Navjot Kaur Bajwa Saloni","doi":"10.21276/ijcmr.2019.6.11.2","DOIUrl":"https://doi.org/10.21276/ijcmr.2019.6.11.2","url":null,"abstract":"Introduction: In patients with cirrhosis, albumin synthesis is decreased because of the loss of hepatic cell mass. Adrenal insufficiency (AI) has been demonstrated in patients with severe liver disease. The percentage of AI in cirrhotic patients varies among different studies and depends on different methods and criteria used to evaluate adrenal function. As both serum albumin and cortisol levels are low in cirrhotic patients we want to determine relationship between serum albumin and cortisol levels. Current research aimed to study adrenal insufficiency in patients of cirrhosis and to determine the relationship between serum albumin and serum cortisol levels. Material and Methods: Prospective study was done on 50 patients of cirrhosis who were admitted in medicine/ gastroenterology ward of DMC & H, Ludhiana. Depending on the levels of cortisol, patients were categorized into 3 groups. Clinically diagnosed patients of cirrhosis were included in our study whereas HIV/Immunodeficiency, Severe chronic heart disease, Chronic obstructive lung disease, Chronic hemodialysis, Severe sepsis, septic shock and patients on steroid therapy were excluded. Results: The data was analyzed using Microsoft excel and SPSS version 20.0 (IBM SPSS, Chicago, Illinois). Mean and standard deviation were computed for the variables. The comparison between groups were done by Chi square and ANOVA. AI was present in 14 (28%) patients of Cirrhosis. The difference between cortisol levels with respect to Albumin was found to be statistically significant (0.05). Conclusion: AI forms important part of spectrum of Cirrhosis and these patients should be evaluated for adrenal dysfunction.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75310888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-01DOI: 10.21276/ijcmr.2019.6.11.12
P. S. Chauhan, Samarjeet Singh, Manu Dogra, V. Sood, K. Kumari, Prajala Chetri
Introduction: Arteriovenous Fistula (AVF) is the preferred vascular access with the least rate of complications and morbidities. Across the globe except European countries AVF is created predominantly by surgeons. There are very few experiences shared by Nephrologists from Indian subcontinent in creating AV fistulas and their follow up. The aim of this study was to assess preoperative factors affecting the outcome of AVF creation and the follow up of successfully created fistulas. Material and Methods: A prospective observational study was carried at our hospital over a period of six months from 01 October 2018 to 31 March 2019. All patients undergoing AVF creation by nephrologist from 01 October 2018 to 15 Feb 2019 were included in the study and each patient was followed for six weeks. Besides baseline parameter, history of Diabetes, hypertension and coronary and peripheral vascular disease were noted. All the perioperative findings like vascular calcification and Blood pressure were noted. All successful AVF were followed for six weeks with serial USG and Doppler at postoperative day 1, 2 week and 6 weeks. Results: A total of 20 (77%) out of 26 AVF were successfully created, The average age was 54.6±15.4 years, Among baseline parameters gender had statistical significance (p=0.03). During surgery more arterial diameter and hypertension were associated with successful outcome. During follow-up, both arterial and venous diameter as well as blood flow in artery and AVF had significant correlation between postoperative 1st, 2nd and 6th week (p<0.01). More than 35% and 80% of patients at 2 and 6 weeks respectively achieved criteria for successful maturation as per NKFKDOQI criteria and it was > 90% and 100% as per UAB criteria. Conclusion: Our experience suggest good outcome of AVF creation by nephrologist, even with those with risk factors for failure and non maturation. Also we suggest early cannulation of AVF at four weeks or earlier.
{"title":"Arteriovenous Fistula Creation by Nephrologist: A Single Centre Experience","authors":"P. S. Chauhan, Samarjeet Singh, Manu Dogra, V. Sood, K. Kumari, Prajala Chetri","doi":"10.21276/ijcmr.2019.6.11.12","DOIUrl":"https://doi.org/10.21276/ijcmr.2019.6.11.12","url":null,"abstract":"Introduction: Arteriovenous Fistula (AVF) is the preferred vascular access with the least rate of complications and morbidities. Across the globe except European countries AVF is created predominantly by surgeons. There are very few experiences shared by Nephrologists from Indian subcontinent in creating AV fistulas and their follow up. The aim of this study was to assess preoperative factors affecting the outcome of AVF creation and the follow up of successfully created fistulas. Material and Methods: A prospective observational study was carried at our hospital over a period of six months from 01 October 2018 to 31 March 2019. All patients undergoing AVF creation by nephrologist from 01 October 2018 to 15 Feb 2019 were included in the study and each patient was followed for six weeks. Besides baseline parameter, history of Diabetes, hypertension and coronary and peripheral vascular disease were noted. All the perioperative findings like vascular calcification and Blood pressure were noted. All successful AVF were followed for six weeks with serial USG and Doppler at postoperative day 1, 2 week and 6 weeks. Results: A total of 20 (77%) out of 26 AVF were successfully created, The average age was 54.6±15.4 years, Among baseline parameters gender had statistical significance (p=0.03). During surgery more arterial diameter and hypertension were associated with successful outcome. During follow-up, both arterial and venous diameter as well as blood flow in artery and AVF had significant correlation between postoperative 1st, 2nd and 6th week (p<0.01). More than 35% and 80% of patients at 2 and 6 weeks respectively achieved criteria for successful maturation as per NKFKDOQI criteria and it was > 90% and 100% as per UAB criteria. Conclusion: Our experience suggest good outcome of AVF creation by nephrologist, even with those with risk factors for failure and non maturation. Also we suggest early cannulation of AVF at four weeks or earlier.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"201 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86416560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-01DOI: 10.21276/ijcmr.2019.6.10.40
Z. Wani, M. M. Mir, A. Raina, Shaheen Nazir Lone, Ursilla Taranum
Introduction: The prevalence and histopathological type of gastric polyp vary between populations. In the recent past aggressive treatment of Helicobacter pylori (H. pylori) and the excessive use of proton pump inhibitors (PPIs) have altered the prevalence of specific types of gastric polyp. This study was designed to evaluate the prevalence and histopathology background of gastric mucosa in cases with fundic gland polyps (FGP). Material and Methods: The medical record of patients who underwent esophagogastroduodenoscopy in 2 centers in Northern India from 2011-2018 were reviewed. Results: The prevalence of gastric polyps was 5%, of which 900 (50%) were fundic gland polyps (FGP). Mean age of presentation was 51.42 years, 70% were located in fundus/ corpus, 62% had dyspepsia, chronic inactive gastritis (CIG) was present in 60%, 95% were multiple and 27% were more than 1cm in size. Conclusions: As a result of anti H. pylori treatment and the excessive use of PPIs, FGP are most common in Northern India. CIG, H. pylori gastritis and Intestinal metaplasia were seen in gastric histology of the cases. These results are interesting and provide new perspective to look for pathogenesis of gastric polyps.
{"title":"Changing Prevalence of Gastric Fundic Gland Polyps: Current Scenario in North India.","authors":"Z. Wani, M. M. Mir, A. Raina, Shaheen Nazir Lone, Ursilla Taranum","doi":"10.21276/ijcmr.2019.6.10.40","DOIUrl":"https://doi.org/10.21276/ijcmr.2019.6.10.40","url":null,"abstract":"Introduction: The prevalence and histopathological type of gastric polyp vary between populations. In the recent past aggressive treatment of Helicobacter pylori (H. pylori) and the excessive use of proton pump inhibitors (PPIs) have altered the prevalence of specific types of gastric polyp. This study was designed to evaluate the prevalence and histopathology background of gastric mucosa in cases with fundic gland polyps (FGP). Material and Methods: The medical record of patients who underwent esophagogastroduodenoscopy in 2 centers in Northern India from 2011-2018 were reviewed. Results: The prevalence of gastric polyps was 5%, of which 900 (50%) were fundic gland polyps (FGP). Mean age of presentation was 51.42 years, 70% were located in fundus/ corpus, 62% had dyspepsia, chronic inactive gastritis (CIG) was present in 60%, 95% were multiple and 27% were more than 1cm in size. Conclusions: As a result of anti H. pylori treatment and the excessive use of PPIs, FGP are most common in Northern India. CIG, H. pylori gastritis and Intestinal metaplasia were seen in gastric histology of the cases. These results are interesting and provide new perspective to look for pathogenesis of gastric polyps.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74010324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-01DOI: 10.21276/ijcmr.2019.6.10.46
Lalnuntluangi Khiangte, P. Naveen
introduction: The uvea plays an important role in ocular immunological defense mechanism. Immunologically speaking, the eye has a deviant and privileged position because of the blood retina barriers, absence of lymphatic drainage and a special feature called anterior chamber associated deviation. This special defense mechanism contributed to the preservation of vision. If these mechanism fail, intraocular inflammation will arise, which may lead to blindness. The aim of this research is to find out the incidence of blindness in patients with uveitis. Material and methods: In this study, 50 cases of uveitis attending ophthalmic out patients and those who are admitted in department of ophthalmology, Regional Institute of Medical Sciences, Imphal were studied to find out clinical incidence of blindness. All the patients were subjected to detailed ocular examination including visual acuity, slit lamp biomicroscopy, direct/indirect ophthalmoscopy and intraocular pressure was recorded. results: Out of 50 patients examined, 20 cases (40%) developed blindness or visual impairment. Bilateral loss of vision developed in 5 cases (10%) and unilateral loss of vision occurred in 11 cases (22%). conclusion: Uveitis was found to be more common in the age group of 21 – 30 years with male preponderance. The main cause of visual loss were secondary glaucoma and cataract. Patients with panuveitis had the worst visual prognosis.
{"title":"Prevalence of Blindness in Patients with Uveitis.","authors":"Lalnuntluangi Khiangte, P. Naveen","doi":"10.21276/ijcmr.2019.6.10.46","DOIUrl":"https://doi.org/10.21276/ijcmr.2019.6.10.46","url":null,"abstract":"introduction: The uvea plays an important role in ocular immunological defense mechanism. Immunologically speaking, the eye has a deviant and privileged position because of the blood retina barriers, absence of lymphatic drainage and a special feature called anterior chamber associated deviation. This special defense mechanism contributed to the preservation of vision. If these mechanism fail, intraocular inflammation will arise, which may lead to blindness. The aim of this research is to find out the incidence of blindness in patients with uveitis. Material and methods: In this study, 50 cases of uveitis attending ophthalmic out patients and those who are admitted in department of ophthalmology, Regional Institute of Medical Sciences, Imphal were studied to find out clinical incidence of blindness. All the patients were subjected to detailed ocular examination including visual acuity, slit lamp biomicroscopy, direct/indirect ophthalmoscopy and intraocular pressure was recorded. results: Out of 50 patients examined, 20 cases (40%) developed blindness or visual impairment. Bilateral loss of vision developed in 5 cases (10%) and unilateral loss of vision occurred in 11 cases (22%). conclusion: Uveitis was found to be more common in the age group of 21 – 30 years with male preponderance. The main cause of visual loss were secondary glaucoma and cataract. Patients with panuveitis had the worst visual prognosis.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"08 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72549352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-01DOI: 10.21276/ijcmr.2019.6.10.17
V. Patel, Asha Vagadiya
Introduction: Stroke is the common cause of severe disability and death worldwide. Study aimed to evaluate etiological, demographic, clinical course and identification of risk factors in acute ischemic cerebrovascular stroke. Material and methods: A prospective study of 46 patients of Ischemic cerebrovascular stroke conducted at Medical College, Vadodara during January 2014 to November 2014. All Patients were subjected to Personal biodata and detailed clinical assessment with written consent. All were sent for routine blood investigations including Lipid profile, chest x ray PA view, Electrocardiography, 2D Echo and CT Scan. All Data were analysed by using Microsoft excel software. Results: In our study, most common age group was 55 to 64 yrs (mean age 55.5yrs) with males predominance was observed (52%). Among males, 26 (56.53%) patients were smokers while 18 (39.13%) males were alcoholic. Amongst 46 patients, 55% and 35% found to be hypertensive and Diabetic respectively. 24% Patients had positive family history of Hypertension. In our study, 54.3% had normal serum cholesterol level between 150 to 199 mg/dl while Hypertriglyceridemia and low HDL was found in 17.4% and 26% respectively. Most common documented risk factors for stroke were age, smoking, hypertension and Diabetes Mellitus. Most of Patients presented with limb/motor weakness (86.9%) followed by speech disturbance and loss of consciousness at 41.3% and 34.7% respectively. Hospital outcome was good. Conclusion: Ischemic stroke entails high socioeconomic burden due to increased morbidity and mortality. Age, Smoking, Hypertension and Diabetes are important atherosclerotic risk factors in our study. Early Identification, treatment and prevention of risk factors can decline the incidence, complications and related mortality. So Physician have a important role in stroke prevention by encouraging the reduction in risk factors.
{"title":"Clinical Profile of Acute Ischemic Cerebrovascular Stroke.","authors":"V. Patel, Asha Vagadiya","doi":"10.21276/ijcmr.2019.6.10.17","DOIUrl":"https://doi.org/10.21276/ijcmr.2019.6.10.17","url":null,"abstract":"Introduction: Stroke is the common cause of severe disability and death worldwide. Study aimed to evaluate etiological, demographic, clinical course and identification of risk factors in acute ischemic cerebrovascular stroke. Material and methods: A prospective study of 46 patients of Ischemic cerebrovascular stroke conducted at Medical College, Vadodara during January 2014 to November 2014. All Patients were subjected to Personal biodata and detailed clinical assessment with written consent. All were sent for routine blood investigations including Lipid profile, chest x ray PA view, Electrocardiography, 2D Echo and CT Scan. All Data were analysed by using Microsoft excel software. Results: In our study, most common age group was 55 to 64 yrs (mean age 55.5yrs) with males predominance was observed (52%). Among males, 26 (56.53%) patients were smokers while 18 (39.13%) males were alcoholic. Amongst 46 patients, 55% and 35% found to be hypertensive and Diabetic respectively. 24% Patients had positive family history of Hypertension. In our study, 54.3% had normal serum cholesterol level between 150 to 199 mg/dl while Hypertriglyceridemia and low HDL was found in 17.4% and 26% respectively. Most common documented risk factors for stroke were age, smoking, hypertension and Diabetes Mellitus. Most of Patients presented with limb/motor weakness (86.9%) followed by speech disturbance and loss of consciousness at 41.3% and 34.7% respectively. Hospital outcome was good. Conclusion: Ischemic stroke entails high socioeconomic burden due to increased morbidity and mortality. Age, Smoking, Hypertension and Diabetes are important atherosclerotic risk factors in our study. Early Identification, treatment and prevention of risk factors can decline the incidence, complications and related mortality. So Physician have a important role in stroke prevention by encouraging the reduction in risk factors.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78704636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-01DOI: 10.21276/ijcmr.2019.6.10.51
A. Agarwal, Jovanovic Boris, S. Misra, D. Chopra
Introduction: Rehabilitation of patients with flabby ridges poses a great amount of difficulty for a prosthodontist. As the flabby tissues easily gets distorted while impression making, the dentures fabricated on such foundations are often compromised in its retention and stability. Case report: Liquid supported denture fabricated using modified window impression technique in this case uses mucostatic impression technique where flabby tissue is located and the denture base is covered with a preshaped, closed fitting flexible PVC sheet which help in continued adaptation of the denture to the mucosa in the resting and functional states. Conclusion: Liquid supported denture fabricated using modified window impression technique can stand a better option in case of flabby ridges while considering conventional prosthodontics. This concept can further improve the patient’s comfort and acceptance because of uniform distribution of masticatory forces.
{"title":"Management of Flabby Ridge using Modified Window Technique and Liquid Supported Denture: A Case Report","authors":"A. Agarwal, Jovanovic Boris, S. Misra, D. Chopra","doi":"10.21276/ijcmr.2019.6.10.51","DOIUrl":"https://doi.org/10.21276/ijcmr.2019.6.10.51","url":null,"abstract":"Introduction: Rehabilitation of patients with flabby ridges poses a great amount of difficulty for a prosthodontist. As the flabby tissues easily gets distorted while impression making, the dentures fabricated on such foundations are often compromised in its retention and stability. Case report: Liquid supported denture fabricated using modified window impression technique in this case uses mucostatic impression technique where flabby tissue is located and the denture base is covered with a preshaped, closed fitting flexible PVC sheet which help in continued adaptation of the denture to the mucosa in the resting and functional states. Conclusion: Liquid supported denture fabricated using modified window impression technique can stand a better option in case of flabby ridges while considering conventional prosthodontics. This concept can further improve the patient’s comfort and acceptance because of uniform distribution of masticatory forces.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77374556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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