首页 > 最新文献

International Journal of Dentistry最新文献

英文 中文
Comparison of the Microhardness of Primary Dentin With Artificially Induced Caries Following the Application of Sodium Fluoride Varnish With the Intensive Technique Versus Fluoride Therapy With Silver Diamine Fluoride. 氟化钠强化清漆与氟化二胺银加氟治疗后牙本质显微硬度的比较
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.1155/ijod/7229454
Sima Rafiei, Ahmad Jafari Ghavam Abad, Mehrsa Paryab, Golnaz Tayebi, Shima Younespour

Background and objective: Black discoloration is a major challenge encountered when using silver diamine fluoride (SDF) to manage early childhood caries (ECC). This study aimed to assess the carious primary dentin microhardness following the application of sodium fluoride (NaF) varnish with the intensive technique versus fluoride therapy with SDF.

Materials and methods: In this in vitro study, 45 extracted relatively sound primary molars were randomly assigned to three groups: Group 1: Application of 30% SDF, Group 2: Application of Aria Dent varnish (5% NaF) three times within 10 days, and Group 3: Application of MI varnish (5% NaF + casein-phosphopeptide amorphous calcium phosphate [CPP-ACP]) three times within 10 days. After sectioning and dentin surface preparation, dentin microhardness was measured at four different time points: baseline, after demineralization, and 24 h and 45 days after the application of the respective fluoride product. The teeth were under pH-cycling throughout the entire study period. The microhardness values were compared among the groups, and at different time points using the generalized estimating equations (GEEs) model.

Results: The mean microhardness at 24 h after treatment was not significantly different from that after demineralization in any group (p > 0.05). The mean microhardness significantly decreased in the 30% SDF group and significantly increased in the two NaF varnish groups at 45 days compared to 24 h (p  < 0.05). The pattern of change in microhardness was significantly different among the three groups (p  < 0.0001). MI varnish increased the microhardness significantly more than the other products within the 45-day study period (p  < 0.05).

Conclusions: The intensive protocol of NaF varnish application three times within 10 days, especially MI varnish that contains CPP-ACP, may enhance the microhardness significantly more than SDF in the first month of use. This protocol may be able to serve as an efficient alternative to SDF.

背景与目的:使用氟化二胺银(SDF)治疗儿童早期龋齿(ECC)时,黑变是遇到的主要挑战。本研究旨在评估氟化钠(NaF)清漆强化技术与SDF氟化治疗后牙本质显微硬度的变化。材料与方法:将45颗离体比较健康的初生磨牙随机分为3组:第1组:30% SDF涂抹,第2组:5% NaF涂抹3次,10 d内,第3组:MI涂3次(5% NaF +酪蛋白-磷酸肽无定形磷酸钙[CPP-ACP])。在牙本质切片和牙本质表面制备后,在基线、脱矿后、应用氟产品后24小时和45天四个不同的时间点测量牙本质显微硬度。在整个研究期间,牙齿都处于ph循环状态。采用广义估计方程(GEEs)模型比较各组和不同时间点的显微硬度值。结果:各组治疗后24h的显微硬度与脱矿后比较差异无统计学意义(p < 0.05)。与24 h相比,30% SDF组的平均显微硬度在45 d时显著降低,而NaF清漆组和NaF清漆组的平均显微硬度在24 h时显著升高(p < 0.05)。三组患者显微硬度变化规律差异有统计学意义(p < 0.0001)。在45天的研究期内,MI清漆对显微硬度的提高显著高于其他产品(p < 0.05)。结论:10天内3次强化应用NaF清漆,特别是含有CPP-ACP的MI清漆,在使用的第一个月内对显微硬度的提高明显高于SDF。该协议可以作为SDF的有效替代方案。
{"title":"Comparison of the Microhardness of Primary Dentin With Artificially Induced Caries Following the Application of Sodium Fluoride Varnish With the Intensive Technique Versus Fluoride Therapy With Silver Diamine Fluoride.","authors":"Sima Rafiei, Ahmad Jafari Ghavam Abad, Mehrsa Paryab, Golnaz Tayebi, Shima Younespour","doi":"10.1155/ijod/7229454","DOIUrl":"https://doi.org/10.1155/ijod/7229454","url":null,"abstract":"<p><strong>Background and objective: </strong>Black discoloration is a major challenge encountered when using silver diamine fluoride (SDF) to manage early childhood caries (ECC). This study aimed to assess the carious primary dentin microhardness following the application of sodium fluoride (NaF) varnish with the intensive technique versus fluoride therapy with SDF.</p><p><strong>Materials and methods: </strong>In this in vitro study, 45 extracted relatively sound primary molars were randomly assigned to three groups: Group 1: Application of 30% SDF, Group 2: Application of Aria Dent varnish (5% NaF) three times within 10 days, and Group 3: Application of MI varnish (5% NaF + casein-phosphopeptide amorphous calcium phosphate [CPP-ACP]) three times within 10 days. After sectioning and dentin surface preparation, dentin microhardness was measured at four different time points: baseline, after demineralization, and 24 h and 45 days after the application of the respective fluoride product. The teeth were under pH-cycling throughout the entire study period. The microhardness values were compared among the groups, and at different time points using the generalized estimating equations (GEEs) model.</p><p><strong>Results: </strong>The mean microhardness at 24 h after treatment was not significantly different from that after demineralization in any group (<i>p</i> > 0.05). The mean microhardness significantly decreased in the 30% SDF group and significantly increased in the two NaF varnish groups at 45 days compared to 24 h (<i>p</i>  < 0.05). The pattern of change in microhardness was significantly different among the three groups (<i>p</i>  < 0.0001). MI varnish increased the microhardness significantly more than the other products within the 45-day study period (<i>p</i>  < 0.05).</p><p><strong>Conclusions: </strong>The intensive protocol of NaF varnish application three times within 10 days, especially MI varnish that contains CPP-ACP, may enhance the microhardness significantly more than SDF in the first month of use. This protocol may be able to serve as an efficient alternative to SDF.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"7229454"},"PeriodicalIF":2.2,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12881696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross-Sectional Study on the Relationship of Some Prognostic Factors of Endodontic Treatment With the Presence and Size of Periapical Lesions in Endodontically Treated Mandibular Anterior and Premolar Teeth Using Cone-Beam Computed Tomography. 锥形束计算机断层扫描对牙髓治疗后下颌前磨牙根尖周病变存在及大小与牙髓治疗预后影响因素的横断面研究
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-06 eCollection Date: 2026-01-01 DOI: 10.1155/ijod/9937176
Nazanin Zargar, Ali Akbar Ahmadi, Ayeh Etemadi, Yaser Safi, Seyedeh Sareh Hendi, Alireza Akbarzadeh Baghban

Objectives: This study evaluated the association between key prognostic factors in nonsurgical endodontic treatment and the presence and size of periapical lesions (PALs) in mandibular anterior and premolar teeth using cone-beam computed tomography (CBCT).

Materials and methods: A cross-sectional analysis was conducted on 63 CBCT scans covering 105 mandibular anterior and premolar teeth. Variables examined included missed canals, underfilled or overfilled canals, procedural errors (e.g., perforations and fractured instruments), intracanal posts (cast or prefabricated), and restoration type. The presence and volume of PALs were assessed, and associations were evaluated using a general linear model (GLM) and multiple logistic regression (α = 0.05).

Results: Among 63 patients (27 males and 36 females), PALs were observed in 43 teeth (41%) with an average lesion volume of 7.90 mm3. No significant association was found between PAL occurrence and age, gender, tooth type, restoration type, or intracanal posts (p  > 0.05). However, missed canals (p = 0.042), underfilled (p  < 0.001), overfilled canals (p  < 0.001), perforations (p = 0.020), and fractured instruments (p = 0.033) were significantly associated with PAL presence. Lesion size correlated significantly with gender (p = 0.047), overfilling (p = 0.013), fractured instruments (p  < 0.001), and apical perforations (p = 0.009).

Conclusions: The findings underscore the clinical relevance of missed canals, over- and underfilling, and procedural mishaps in the development and size of PALs. Patient gender also appeared to influence lesion size. These results highlight the need for precision in endodontic procedures to improve periapical healing.

目的:本研究利用锥形束计算机断层扫描(CBCT)评估非手术根管治疗中关键预后因素与下颌前磨牙根尖周病变(PALs)的存在和大小之间的关系。材料与方法:对105颗下颌骨前、前磨牙的63张CBCT扫描结果进行横断面分析。检查的变量包括遗漏的根管、未填充或过度填充的根管、操作错误(如穿孔和器械断裂)、管内桩(铸造或预制)和修复类型。采用一般线性模型(GLM)和多元逻辑回归(α = 0.05)评估PALs的存在和体积,并评估其相关性。结果:63例患者(男性27例,女性36例)中,有43颗牙(41%)出现PALs,平均病变体积为7.90 mm3。PAL的发生与年龄、性别、牙型、修复体类型、管内桩均无显著相关性(p < 0.05)。然而,遗漏的椎管(p = 0.042)、未填充的椎管(p < 0.001)、过填充的椎管(p < 0.001)、穿孔(p = 0.020)和器械断裂(p = 0.033)与PAL的存在显著相关。病变大小与性别(p = 0.047)、过度填充(p = 0.013)、器械断裂(p < 0.001)和根尖穿孔(p = 0.009)显著相关。结论:研究结果强调了肛管遗漏、过充填和欠充填以及肛管发展和大小的手术失误的临床意义。患者性别似乎也影响病变大小。这些结果强调需要精确的根管治疗,以提高根尖周愈合。
{"title":"Cross-Sectional Study on the Relationship of Some Prognostic Factors of Endodontic Treatment With the Presence and Size of Periapical Lesions in Endodontically Treated Mandibular Anterior and Premolar Teeth Using Cone-Beam Computed Tomography.","authors":"Nazanin Zargar, Ali Akbar Ahmadi, Ayeh Etemadi, Yaser Safi, Seyedeh Sareh Hendi, Alireza Akbarzadeh Baghban","doi":"10.1155/ijod/9937176","DOIUrl":"https://doi.org/10.1155/ijod/9937176","url":null,"abstract":"<p><strong>Objectives: </strong>This study evaluated the association between key prognostic factors in nonsurgical endodontic treatment and the presence and size of periapical lesions (PALs) in mandibular anterior and premolar teeth using cone-beam computed tomography (CBCT).</p><p><strong>Materials and methods: </strong>A cross-sectional analysis was conducted on 63 CBCT scans covering 105 mandibular anterior and premolar teeth. Variables examined included missed canals, underfilled or overfilled canals, procedural errors (e.g., perforations and fractured instruments), intracanal posts (cast or prefabricated), and restoration type. The presence and volume of PALs were assessed, and associations were evaluated using a general linear model (GLM) and multiple logistic regression (<i>α</i> = 0.05).</p><p><strong>Results: </strong>Among 63 patients (27 males and 36 females), PALs were observed in 43 teeth (41%) with an average lesion volume of 7.90 mm<sup>3</sup>. No significant association was found between PAL occurrence and age, gender, tooth type, restoration type, or intracanal posts (<i>p</i>  > 0.05). However, missed canals (<i>p</i> = 0.042), underfilled (<i>p</i>  < 0.001), overfilled canals (<i>p</i>  < 0.001), perforations (<i>p</i> = 0.020), and fractured instruments (<i>p</i> = 0.033) were significantly associated with PAL presence. Lesion size correlated significantly with gender (<i>p</i> = 0.047), overfilling (<i>p</i> = 0.013), fractured instruments (<i>p</i>  < 0.001), and apical perforations (<i>p</i> = 0.009).</p><p><strong>Conclusions: </strong>The findings underscore the clinical relevance of missed canals, over- and underfilling, and procedural mishaps in the development and size of PALs. Patient gender also appeared to influence lesion size. These results highlight the need for precision in endodontic procedures to improve periapical healing.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"9937176"},"PeriodicalIF":2.2,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12880948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Various Surface Treatments on Adhesion Between Co-Cr Alloy and Acrylic Teeth. 不同表面处理对钴铬合金与丙烯酸齿间附着力的影响。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-05 eCollection Date: 2026-01-01 DOI: 10.1155/ijod/2199689
Punnita Chotcomwongse, Pongsakorn Apinsathanon, Basel Mahardawi, Palawat Laoharungpisit, Pheeradej Na Nan, Napapa Aimjirakul

Objective: This study aimed to assess the shear bond strength (SBS) between cobalt-chromium (Co-Cr) alloy and acrylic resin teeth using various surface conditioning methods and to investigate the failure modes associated with these methods.

Materials and methods: A total of 53 Co-Cr specimens were fabricated and randomly assigned to five groups (n = 10 per group) based on the type of surface treatment: (1) polymethyl methacrylate (PMMA; control group), (2) Clearfil Ceramic Primer Plus + PMMA, (3) M&C Primer + PMMA, (4) Super-Bond Universal, and (5) M&C Primer + Super-Bond Universal. Each specimen was subsequently bonded to an acrylic resin tooth. Three specimens from both the control and primer-treated groups were reserved for scanning electron microscopy (SEM) analysis. All samples were stored in distilled water at 37 ± 1°C for 24 h before SBS evaluation with a universal testing machine.

Statistical analysis: Statistical analysis was performed using one-way analysis of variance (ANOVA) followed by Tukey's HSD post hoc test.

Results: A statistically significant difference in bond strength was observed among the experimental groups (p < 0.05), with the Super-Bond Universal group exhibiting the highest bond strength (8.01 ± 1.05 megapascals [MPa]), compared to the control group (3.07 ± 0.48 MPa). The control group and the PMMA + M&C Primer group exhibited predominantly adhesive failures, while the other groups showed a combination of adhesive and mixed failures.

Conclusion: Super-Bond Universal without primer achieved the highest bond strength, and the application of primers prior to PMMA or resin cement placement significantly improved bonding between Co-Cr alloys and acrylic resin teeth, suggesting that appropriate surface conditioning can enhance denture repair outcomes.

目的:研究不同表面处理方法对钴铬合金(Co-Cr)牙与丙烯酸树脂牙的剪切结合强度(SBS)的影响,并探讨这些处理方法的失效模式。材料和方法:共制备53个Co-Cr样品,根据表面处理类型随机分为5组(n = 10):(1)聚甲基丙烯酸甲酯(PMMA,对照组),(2)Clearfil Ceramic Primer Plus + PMMA, (3) M&C Primer + PMMA, (4) Super-Bond Universal, (5) M&C Primer + Super-Bond Universal。每个标本随后被粘在丙烯酸树脂牙齿上。从对照组和引物处理组各保留3个标本用于扫描电子显微镜(SEM)分析。所有样品在37±1°C的蒸馏水中保存24 h,然后用通用试验机进行SBS评估。统计分析:采用单因素方差分析(ANOVA)进行统计分析,并进行Tukey’s HSD事后检验。结果:各实验组间的结合强度差异有统计学意义(p < 0.05),其中Super-Bond Universal组的结合强度最高(8.01±1.05兆帕斯卡[MPa]),对照组为3.07±0.48兆帕斯卡(MPa)。对照组和PMMA + M&C Primer组主要表现为粘接失败,而其他组表现为粘接和混合失败的组合。结论:Super-Bond Universal在不使用底物的情况下粘接强度最高,在PMMA或树脂水泥植入前使用底物可显著改善Co-Cr合金与丙烯酸树脂牙的粘接,提示适当的表面处理可提高义齿修复效果。
{"title":"The Impact of Various Surface Treatments on Adhesion Between Co-Cr Alloy and Acrylic Teeth.","authors":"Punnita Chotcomwongse, Pongsakorn Apinsathanon, Basel Mahardawi, Palawat Laoharungpisit, Pheeradej Na Nan, Napapa Aimjirakul","doi":"10.1155/ijod/2199689","DOIUrl":"https://doi.org/10.1155/ijod/2199689","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to assess the shear bond strength (SBS) between cobalt-chromium (Co-Cr) alloy and acrylic resin teeth using various surface conditioning methods and to investigate the failure modes associated with these methods.</p><p><strong>Materials and methods: </strong>A total of 53 Co-Cr specimens were fabricated and randomly assigned to five groups (<i>n</i> = 10 per group) based on the type of surface treatment: (1) polymethyl methacrylate (PMMA; control group), (2) Clearfil Ceramic Primer Plus + PMMA, (3) M&C Primer + PMMA, (4) Super-Bond Universal, and (5) M&C Primer + Super-Bond Universal. Each specimen was subsequently bonded to an acrylic resin tooth. Three specimens from both the control and primer-treated groups were reserved for scanning electron microscopy (SEM) analysis. All samples were stored in distilled water at 37 ± 1°C for 24 h before SBS evaluation with a universal testing machine.</p><p><strong>Statistical analysis: </strong>Statistical analysis was performed using one-way analysis of variance (ANOVA) followed by Tukey's HSD post hoc test.</p><p><strong>Results: </strong>A statistically significant difference in bond strength was observed among the experimental groups (<i>p</i> < 0.05), with the Super-Bond Universal group exhibiting the highest bond strength (8.01 ± 1.05 megapascals [MPa]), compared to the control group (3.07 ± 0.48 MPa). The control group and the PMMA + M&C Primer group exhibited predominantly adhesive failures, while the other groups showed a combination of adhesive and mixed failures.</p><p><strong>Conclusion: </strong>Super-Bond Universal without primer achieved the highest bond strength, and the application of primers prior to PMMA or resin cement placement significantly improved bonding between Co-Cr alloys and acrylic resin teeth, suggesting that appropriate surface conditioning can enhance denture repair outcomes.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"2199689"},"PeriodicalIF":2.2,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12876040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tensile Strength of Nylon Sutures Versus Polyglycolic Acid Sutures Immersed in Camu camu (Myrciaria dubia) and Tumbo (Passiflora tripartita) Juices: A Linear Regression Model. 尼龙缝线与聚乙醇酸缝线浸在桃金娘(Myrciaria dubia)和Tumbo (Passiflora tripartita)果汁中的抗拉强度:一个线性回归模型。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-04 eCollection Date: 2026-01-01 DOI: 10.1155/ijod/4015454
Tania Mamani-Salinas, Daniel Alvitez-Temoche, Cesar Mauricio-Vilchez, Fran Espinoza-Carhuancho, Oscar Sotomayor, Julia Medina, Frank Mayta-Tovalino

Objective: To evaluate the predictors of tensile strength of nylon and polyglycolic acid when immersed in Peruvian camu camu and tumbo juices.

Methods: An in vitro experimental and comparative study was conducted following the CRIS guidelines for reporting laboratory studies. A total of 192 samples of sutures were tested under laboratory conditions, measuring their initial resistance at days 3, 7, and 14. The juices, prepared in an artisanal way to preserve their natural characteristics, were monitored for pH daily. Mechanical tests were performed using a digital tensile machine, and data were analyzed with Stata 17.0 statistical software using Student's t-tests and linear regression.

Results: Both materials displayed a timewise decrease in strength, with polyglycolic acid being stronger than nylon at all time points measured. At time 0 polyglycolic acid and nylon were noted as 12.23 ± 0.40 N and 8.94 ± 0.17 N, respectively. At day 14 polyglycolic acid and nylon were noted as 11.24 ± 0.38 N and 7.59 ± 0.38 N, respectively. The camu camu juice and the tumbo juice displayed similar effects (p > 0.05), and pH was the only feature to display a significant decrease per unit variation (p < 0.05).

Conclusion: Such a conclusion tends to confirm the greater acid resistance of polyglycolic acid over nylon and adds more weight to pH as a variable affecting suture degradation. We may learn to make more intelligent choices of absorbable sutures at the operating table.

目的:探讨尼龙和聚乙醇酸浸泡在秘鲁camu camu和tumbo果汁中抗拉强度的预测因素。方法:按照CRIS实验室研究报告指南进行体外实验和比较研究。在实验室条件下对192个缝合线样本进行测试,测量其在第3、7和14天的初始阻力。这些果汁以手工方式制备,以保持其自然特性,每天监测pH值。力学试验采用数字拉伸机进行,数据分析采用Stata 17.0统计软件,采用学生t检验和线性回归。结果:两种材料都显示出强度随时间的下降,聚乙醇酸在所有时间点都比尼龙强。时间0时,聚乙醇酸和尼龙分别为12.23±0.40 N和8.94±0.17 N。第14天,聚乙醇酸和尼龙分别为11.24±0.38 N和7.59±0.38 N。camu camu汁和tumbo汁表现出相似的效果(p < 0.05), pH值是唯一单位变异显著降低的特征(p < 0.05)。结论:这一结论倾向于证实聚乙醇酸比尼龙具有更强的耐酸性,并增加了pH值作为影响缝线降解的变量的权重。我们可以学会在手术台上更明智地选择可吸收缝合线。
{"title":"Tensile Strength of Nylon Sutures Versus Polyglycolic Acid Sutures Immersed in Camu camu (<i>Myrciaria dubia</i>) and Tumbo (<i>Passiflora tripartita</i>) Juices: A Linear Regression Model.","authors":"Tania Mamani-Salinas, Daniel Alvitez-Temoche, Cesar Mauricio-Vilchez, Fran Espinoza-Carhuancho, Oscar Sotomayor, Julia Medina, Frank Mayta-Tovalino","doi":"10.1155/ijod/4015454","DOIUrl":"https://doi.org/10.1155/ijod/4015454","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the predictors of tensile strength of nylon and polyglycolic acid when immersed in Peruvian camu camu and tumbo juices.</p><p><strong>Methods: </strong>An in vitro experimental and comparative study was conducted following the CRIS guidelines for reporting laboratory studies. A total of 192 samples of sutures were tested under laboratory conditions, measuring their initial resistance at days 3, 7, and 14. The juices, prepared in an artisanal way to preserve their natural characteristics, were monitored for pH daily. Mechanical tests were performed using a digital tensile machine, and data were analyzed with Stata 17.0 statistical software using Student's <i>t</i>-tests and linear regression.</p><p><strong>Results: </strong>Both materials displayed a timewise decrease in strength, with polyglycolic acid being stronger than nylon at all time points measured. At time 0 polyglycolic acid and nylon were noted as 12.23 ± 0.40 N and 8.94 ± 0.17 N, respectively. At day 14 polyglycolic acid and nylon were noted as 11.24 ± 0.38 N and 7.59 ± 0.38 N, respectively. The camu camu juice and the tumbo juice displayed similar effects (<i>p</i> > 0.05), and pH was the only feature to display a significant decrease per unit variation (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>Such a conclusion tends to confirm the greater acid resistance of polyglycolic acid over nylon and adds more weight to pH as a variable affecting suture degradation. We may learn to make more intelligent choices of absorbable sutures at the operating table.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"4015454"},"PeriodicalIF":2.2,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12872958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Smile Esthetics and Rotated Maxillary Lateral Incisors. 微笑美学与上颌侧门牙旋转。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-04 eCollection Date: 2026-01-01 DOI: 10.1155/ijod/4968959
Alexa Spokane, Daniel Rinchuse, Thomas Zullo, John Burnheimer

Introduction: Although tooth rotations are a common orthodontic problem, little research has addressed how lay observers perceive these rotations. Consequently, the aim of this study is to determine laypersons' esthetic perceptions of changes in the rotation of the maxillary lateral incisors.

Materials and methods: An intraoral digital scan of a female adult's dentition was manipulated with ClinCheck software to create four smile conditions: (A) no rotation either maxillary lateral incisor, (B) 20° mesial-out rotation of both, (C) 30° mesial-out rotation, and (D) 40° mesial-out rotation. Each condition was shown with frontal and three-quarter view images. A panel of laypeople (age 18-30, no dental training) rated the attractiveness of each smile using a 100 mm visual analog scale (VAS; 0 = least esthetic, 100 = most esthetic). The score for each condition was recorded. A mixed-model two-way ANOVA (gender × rotation) with repeated measures was used to analyze the data.

Results: No-rotation smiles were rated significantly more attractive than any smiles with rotated lateral incisors (p  < 0.05). Smiles with a 40° rotation received the lowest esthetic scores and were significantly less attractive than the others (p  < 0.001). Laypersons did not significantly distinguish between 20° and 30° rotations (p  > 0.05). There was no significant difference in ratings between male and female panelists (p = 0.104). No interaction effect between panelist gender and rotation level was observed.

Conclusion: Laypeople preferred the smile with no rotation of the lateral incisors. They could not perceive a notable esthetic difference between 20° and 30° rotations. However, a 40° rotation was perceived as substantially less esthetic. Panelist gender did not affect esthetic ratings.

简介:虽然牙齿旋转是一个常见的正畸问题,很少有研究解决外行人如何看待这些旋转。因此,本研究的目的是确定外行人对上颌侧切牙旋转变化的审美感知。材料和方法:使用ClinCheck软件对女性成人牙列进行口腔内数字扫描,创建四种微笑条件:(a)上颌侧切牙不旋转,(B)两侧均向外旋转20°,(C)向外旋转30°,(D)向外旋转40°。每种情况都显示正面和四分之三视图图像。一组外行人(18-30岁,未接受牙科培训)使用100毫米视觉模拟量表(VAS; 0 =最不美观,100 =最美观)对每个微笑的吸引力进行评分。记录每种情况的得分。采用重复测量的混合模型双向方差分析(性别×旋转)对数据进行分析。结果:不旋转的微笑比旋转侧切牙的微笑更有吸引力(p < 0.05)。旋转40°的微笑获得的审美分数最低,明显不如其他微笑有吸引力(p < 0.001)。外行人在20°和30°旋转之间无显著差异(p < 0.05)。男女小组成员的评分无显著差异(p = 0.104)。小组成员性别与轮换水平之间无交互作用。结论:外行人更喜欢侧门牙不旋转的微笑。他们无法感知20°和30°旋转之间的显著美学差异。然而,40°旋转被认为是非常不美观的。小组成员的性别不影响审美评分。
{"title":"Smile Esthetics and Rotated Maxillary Lateral Incisors.","authors":"Alexa Spokane, Daniel Rinchuse, Thomas Zullo, John Burnheimer","doi":"10.1155/ijod/4968959","DOIUrl":"10.1155/ijod/4968959","url":null,"abstract":"<p><strong>Introduction: </strong>Although tooth rotations are a common orthodontic problem, little research has addressed how lay observers perceive these rotations. Consequently, the aim of this study is to determine laypersons' esthetic perceptions of changes in the rotation of the maxillary lateral incisors.</p><p><strong>Materials and methods: </strong>An intraoral digital scan of a female adult's dentition was manipulated with ClinCheck software to create four smile conditions: (A) no rotation either maxillary lateral incisor, (B) 20° mesial-out rotation of both, (C) 30° mesial-out rotation, and (D) 40° mesial-out rotation. Each condition was shown with frontal and three-quarter view images. A panel of laypeople (age 18-30, no dental training) rated the attractiveness of each smile using a 100 mm visual analog scale (VAS; 0 = least esthetic, 100 = most esthetic). The score for each condition was recorded. A mixed-model two-way ANOVA (gender × rotation) with repeated measures was used to analyze the data.</p><p><strong>Results: </strong>No-rotation smiles were rated significantly more attractive than any smiles with rotated lateral incisors (<i>p</i>  < 0.05). Smiles with a 40° rotation received the lowest esthetic scores and were significantly less attractive than the others (<i>p</i>  < 0.001). Laypersons did not significantly distinguish between 20° and 30° rotations (<i>p</i>  > 0.05). There was no significant difference in ratings between male and female panelists (<i>p</i> = 0.104). No interaction effect between panelist gender and rotation level was observed.</p><p><strong>Conclusion: </strong>Laypeople preferred the smile with no rotation of the lateral incisors. They could not perceive a notable esthetic difference between 20° and 30° rotations. However, a 40° rotation was perceived as substantially less esthetic. Panelist gender did not affect esthetic ratings.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"4968959"},"PeriodicalIF":2.2,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12872039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Microleakage Beneath Orthodontic Molar Bands Cemented With Resin-Modified Glass Ionomer Using Two Enamel Deproteinization Agents. 两种牙釉质脱蛋白剂对树脂改性玻璃离子固化正畸磨牙带微渗漏的评价。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-04 eCollection Date: 2026-01-01 DOI: 10.1155/ijod/5723946
Shabnam Ajami, Maryam Salah, Amirmasoud Rekabpour, Farahnaz Sharafeddin

Objective: The aim of this study was to evaluate the microleakage beneath orthodontic bands cemented with resin-modified glass ionomer (RMGI), following enamel treatment with two different deproteinizing agents in comparison to a control group.

Materials and methods: Thirty-six human third molars were used for this cross-sectional study. The samples were randomly divided into three equal groups of 12. The method of band cementation in each group was as follows: Group I (6% bromelain enzyme as deproteinizer + GC Fuji plus Conditioner + GC Fuji Plus Glass ionomer), Group II (chlorhexidine [CHX] as deproteinizer + GC Fuji Plus Conditioner + Glass ionomer), and Group III (GC Fuji Plus conditioner + GC fuji plus Glass ionomer) as the control group. All samples were sealed and dyed with methylene blue and then exposed to thermocycling. The samples were sectioned and prepared for microleakage evaluation at both occlusal and gingival sides for the enamel-cement interface margins. A stereomicroscope was used to evaluate the amount of dye penetration as the microleakage. Comparison of the microleakage values among the groups was done using the Kruskal-Wallis and Mann-Whitney U test as the post hoc test.

Results: The 6% bromelain enzyme deproteinization showed the least amount of microleakage at both occlusal and CEJ sides of the bands (p  < 0.05). Group II also showed a better microleakage value at the gingival side in comparison to the control group (p  < 0.05).

Conclusion: This study revealed that the pretreatment of enamel with 6% bromelain enzyme significantly reduced the microleakage beneath orthodontic bands cemented with RMGI cement (RMGIC). Improved marginal sealing by 6% bromelain enzyme was significant compared with that of the CHX pretreatment and untreated enamel surfaces.

目的:本研究的目的是评估树脂改性玻璃离子(RMGI)粘接正畸带在两种不同脱蛋白剂治疗牙釉质后的微渗漏情况,并与对照组进行比较。材料与方法:采用36颗人第三磨牙进行横断面研究。这些样本被随机分成三组,每组12人。各组的带胶结方法如下:I组(6%菠萝蛋白酶酶作为脱蛋白剂+ GC富士加护发素+ GC富士加玻璃离子),II组(氯己定[CHX]作为脱蛋白剂+ GC富士加护发素+玻璃离子),III组(GC富士加护发素+ GC富士加玻璃离子)为对照组。所有的样品都被密封并用亚甲基蓝染色,然后暴露在热循环中。将样品切片并准备用于牙合侧和牙龈侧牙釉质-骨水泥界面边缘的微渗漏评估。用体视显微镜观察染料渗透量作为微渗漏量。采用Kruskal-Wallis和Mann-Whitney U检验作为事后检验,比较各组间微渗漏值。结果:6%菠萝蛋白酶酶脱蛋白组牙合侧和CEJ侧微渗漏量最小(p < 0.05)。治疗组龈侧微漏值明显高于对照组(p < 0.05)。结论:6%菠萝蛋白酶酶预处理牙釉质可显著减少RMGI骨水泥(RMGIC)正畸带下的微渗漏。与CHX预处理和未处理的牙釉质表面相比,添加6%菠萝蛋白酶酶可显著改善牙釉质表面的边缘密封性。
{"title":"Evaluation of Microleakage Beneath Orthodontic Molar Bands Cemented With Resin-Modified Glass Ionomer Using Two Enamel Deproteinization Agents.","authors":"Shabnam Ajami, Maryam Salah, Amirmasoud Rekabpour, Farahnaz Sharafeddin","doi":"10.1155/ijod/5723946","DOIUrl":"https://doi.org/10.1155/ijod/5723946","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to evaluate the microleakage beneath orthodontic bands cemented with resin-modified glass ionomer (RMGI), following enamel treatment with two different deproteinizing agents in comparison to a control group.</p><p><strong>Materials and methods: </strong>Thirty-six human third molars were used for this cross-sectional study. The samples were randomly divided into three equal groups of 12. The method of band cementation in each group was as follows: Group I (6% bromelain enzyme as deproteinizer + GC Fuji plus Conditioner + GC Fuji Plus Glass ionomer), Group II (chlorhexidine [CHX] as deproteinizer + GC Fuji Plus Conditioner + Glass ionomer), and Group III (GC Fuji Plus conditioner + GC fuji plus Glass ionomer) as the control group. All samples were sealed and dyed with methylene blue and then exposed to thermocycling. The samples were sectioned and prepared for microleakage evaluation at both occlusal and gingival sides for the enamel-cement interface margins. A stereomicroscope was used to evaluate the amount of dye penetration as the microleakage. Comparison of the microleakage values among the groups was done using the Kruskal-Wallis and Mann-Whitney <i>U</i> test as the post hoc test.</p><p><strong>Results: </strong>The 6% bromelain enzyme deproteinization showed the least amount of microleakage at both occlusal and CEJ sides of the bands (<i>p</i>  < 0.05). Group II also showed a better microleakage value at the gingival side in comparison to the control group (<i>p</i>  < 0.05).</p><p><strong>Conclusion: </strong>This study revealed that the pretreatment of enamel with 6% bromelain enzyme significantly reduced the microleakage beneath orthodontic bands cemented with RMGI cement (RMGIC). Improved marginal sealing by 6% bromelain enzyme was significant compared with that of the CHX pretreatment and untreated enamel surfaces.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"5723946"},"PeriodicalIF":2.2,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12872594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Vitro Evaluation of Apical Transportation Induced by Single- and Dual-Thermally Treated NiTi Instruments. 单、双热处理NiTi器械诱导根尖运输的体外研究。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-04 eCollection Date: 2026-01-01 DOI: 10.1155/ijod/6168069
Francesco Puleio, Rosario Pirri, Jose Aranguren, Vincenzo Tosco

Introduction: Martensitic endodontic instruments, thanks to their flexibility, produce less apical transportation compared to austenitic instruments. Recently, a sequence of instruments featuring a dual thermal treatment applied separately to the tip and the shank was introduced with the aim of achieving a tip with enhanced cutting capacity and a more flexible body. The increased stiffness at the tip could potentially lead to greater apical transportation. The aim of this study was to compare apical transportation produced by SlimShaper (single thermal treatment) and SlimShaper PRO (dual thermal treatment) nickel-titanium (NiTi) instruments (Zarc4Endo, Spain) in standardized simulated canals.

Methods: Forty-four standardized J-shaped resin blocks were used, divided into two groups (n = 22): Group A (shaped with SlimShaper up to size 25/0.04) and Group B (shaped with SlimShaper PRO up to size 25/0.04). Each block was photographed before and after shaping, and the images were superimposed to evaluate apical transportation. Data normality was verified with the Shapiro-Wilk test, and homogeneity of variances was assessed with Levene's test. Since assumptions were met, comparisons between the two groups were performed using the independent Student's t test, with the level of significance set at p  < 0.05.

Results: Mean apical transportation was 0.08423 mm (SD 0.01049) for SlimShaper and 0.08609 mm (SD 0.01102) for SlimShaper PRO, with no statistically significant difference between groups (p = 0.57).

Conclusions: Under the conditions of this study, the dual-thermally treated SlimShaper PRO instruments did not produce greater apical transportation than the single-thermally treated SlimShaper instruments.

马氏体根管器械由于其柔韧性,比奥氏体根管器械产生更少的根尖移动。最近,一系列具有双重热处理的工具分别应用于尖端和刀柄,目的是实现具有增强切割能力和更灵活的身体的尖端。尖端刚度的增加可能会导致更大的根尖运输。本研究的目的是比较SlimShaper(单一热处理)和SlimShaper PRO(双重热处理)镍钛(NiTi)器械(Zarc4Endo,西班牙)在标准化模拟管中产生的根尖运输。方法:采用标准j型树脂块44块,分为两组(n = 22): A组(SlimShaper塑形至25/0.04)和B组(SlimShaper PRO塑形至25/0.04)。在整形前后对每个块进行拍照,并进行图像叠加,评价根尖迁移。采用Shapiro-Wilk检验验证数据正态性,采用Levene检验评估方差的齐性。由于满足假设,两组之间的比较使用独立的学生t检验,显著性水平设置为p < 0.05。结果:SlimShaper的平均根尖移位量为0.08423 mm (SD 0.01049), SlimShaper PRO的平均根尖移位量为0.08609 mm (SD 0.01102),两组间差异无统计学意义(p = 0.57)。结论:在本研究条件下,双热处理的SlimShaper PRO器械并不比单热处理的SlimShaper器械产生更大的根尖移位。
{"title":"In Vitro Evaluation of Apical Transportation Induced by Single- and Dual-Thermally Treated NiTi Instruments.","authors":"Francesco Puleio, Rosario Pirri, Jose Aranguren, Vincenzo Tosco","doi":"10.1155/ijod/6168069","DOIUrl":"10.1155/ijod/6168069","url":null,"abstract":"<p><strong>Introduction: </strong>Martensitic endodontic instruments, thanks to their flexibility, produce less apical transportation compared to austenitic instruments. Recently, a sequence of instruments featuring a dual thermal treatment applied separately to the tip and the shank was introduced with the aim of achieving a tip with enhanced cutting capacity and a more flexible body. The increased stiffness at the tip could potentially lead to greater apical transportation. The aim of this study was to compare apical transportation produced by SlimShaper (single thermal treatment) and SlimShaper PRO (dual thermal treatment) nickel-titanium (NiTi) instruments (Zarc4Endo, Spain) in standardized simulated canals.</p><p><strong>Methods: </strong>Forty-four standardized J-shaped resin blocks were used, divided into two groups (<i>n</i> = 22): Group A (shaped with SlimShaper up to size 25/0.04) and Group B (shaped with SlimShaper PRO up to size 25/0.04). Each block was photographed before and after shaping, and the images were superimposed to evaluate apical transportation. Data normality was verified with the Shapiro-Wilk test, and homogeneity of variances was assessed with Levene's test. Since assumptions were met, comparisons between the two groups were performed using the independent Student's <i>t</i> test, with the level of significance set at <i>p</i>  < 0.05.</p><p><strong>Results: </strong>Mean apical transportation was 0.08423 mm (SD 0.01049) for SlimShaper and 0.08609 mm (SD 0.01102) for SlimShaper PRO, with no statistically significant difference between groups (<i>p</i> = 0.57).</p><p><strong>Conclusions: </strong>Under the conditions of this study, the dual-thermally treated SlimShaper PRO instruments did not produce greater apical transportation than the single-thermally treated SlimShaper instruments.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"6168069"},"PeriodicalIF":2.2,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12872111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Clinical Implications of HPV Infection in Oral Cavity and Oropharynx in HIV+ Men. HIV阳性男性口腔和口咽部HPV感染的患病率及临床意义
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-03 eCollection Date: 2026-01-01 DOI: 10.1155/ijod/7565387
José Adán Vizcaíno-Reséndiz, Jaime F Andrade-Villanueva, Luis Felipe Jave-Suárez, Tonatiuh Abimael Baltazar-Díaz, Felipe De Jesús Bustos-Rodríguez, Luis Eduardo Del Moral-Trinidad, Dana Alejandra Figueroa-González, Juan Carlos Vázquez-Limón, Ana Esther Mercado-González, Luz Alicia González-Hernández

Introduction: Human papillomavirus (HPV) is associated with several types of oral lesions (OLs), including oropharyngeal squamous cell carcinoma (SCC), especially in HIV-positive individuals.

Objectives: To identify the prevalence and clinical implications of the alpha (α) and beta (β) genera of HPV in the oral cavity and oropharynx of HIV-positive men who have sex with men (MSM).

Methods: A cross-sectional study from January 2022 to May 2023 was performed. Ninety-four participants were included; their sexual habits, risk factors, HIV-1 viral load, and CD4+ T-cell counts were obtained. Exfoliative cytology was performed, and deoxyribonucleic acid (DNA) was extracted from the samples to identify α and β HPV genera through endpoint polymerase chain reaction (PCR). OLs associated with HPV infection were described, and histopathological and immunohistochemical findings for p16 were reported.

Results: A total of 71.3% of the participants were positive for any HPV genus (22.4% α-HPV and 49.2% β-HPV). The 6.3% had OLs associated with HPV, principally leukoplakia, and although six of nine samples were p16 positive, none were malignant.

Conclusion: The prevalence of HPV infection in the oral cavity and oropharynx in HIV + MSM was high; however, the associated OLs were infrequent and not malignant. Future studies are necessary to evaluate the clinical relevance of HPV infection and p16-positive OLs.

人乳头瘤病毒(HPV)与几种类型的口腔病变(OLs)相关,包括口咽鳞状细胞癌(SCC),特别是在hiv阳性个体中。目的:了解hiv阳性男男性行为者(MSM)口腔和口咽中α (α)和β (β)属HPV的流行情况及其临床意义。方法:横断面研究于2022年1月至2023年5月进行。94名参与者被纳入;获得他们的性习惯、危险因素、HIV-1病毒载量和CD4+ t细胞计数。对标本进行剥脱细胞学检查,提取脱氧核糖核酸(DNA),通过终点聚合酶链反应(PCR)鉴定α和β HPV属。描述了与HPV感染相关的OLs,并报告了p16的组织病理学和免疫组织化学结果。结果:共有71.3%的参与者HPV属阳性(22.4% α-HPV和49.2% β-HPV)。6.3%的人有与HPV相关的ol,主要是白斑,虽然9个样本中有6个是p16阳性,但没有一个是恶性的。结论:HIV + MSM口腔及口咽部HPV感染率较高;然而,相关的OLs并不常见,也不是恶性的。未来的研究需要评估HPV感染与p16阳性ol的临床相关性。
{"title":"Prevalence and Clinical Implications of HPV Infection in Oral Cavity and Oropharynx in HIV+ Men.","authors":"José Adán Vizcaíno-Reséndiz, Jaime F Andrade-Villanueva, Luis Felipe Jave-Suárez, Tonatiuh Abimael Baltazar-Díaz, Felipe De Jesús Bustos-Rodríguez, Luis Eduardo Del Moral-Trinidad, Dana Alejandra Figueroa-González, Juan Carlos Vázquez-Limón, Ana Esther Mercado-González, Luz Alicia González-Hernández","doi":"10.1155/ijod/7565387","DOIUrl":"10.1155/ijod/7565387","url":null,"abstract":"<p><strong>Introduction: </strong>Human papillomavirus (HPV) is associated with several types of oral lesions (OLs), including oropharyngeal squamous cell carcinoma (SCC), especially in HIV-positive individuals.</p><p><strong>Objectives: </strong>To identify the prevalence and clinical implications of the alpha (α) and beta (β) genera of HPV in the oral cavity and oropharynx of HIV-positive men who have sex with men (MSM).</p><p><strong>Methods: </strong>A cross-sectional study from January 2022 to May 2023 was performed. Ninety-four participants were included; their sexual habits, risk factors, HIV-1 viral load, and CD4<sup>+</sup> T-cell counts were obtained. Exfoliative cytology was performed, and deoxyribonucleic acid (DNA) was extracted from the samples to identify α and β HPV genera through endpoint polymerase chain reaction (PCR). OLs associated with HPV infection were described, and histopathological and immunohistochemical findings for p16 were reported.</p><p><strong>Results: </strong>A total of 71.3% of the participants were positive for any HPV genus (22.4% α-HPV and 49.2% β-HPV). The 6.3% had OLs associated with HPV, principally leukoplakia, and although six of nine samples were p16 positive, none were malignant.</p><p><strong>Conclusion: </strong>The prevalence of HPV infection in the oral cavity and oropharynx in HIV + MSM was high; however, the associated OLs were infrequent and not malignant. Future studies are necessary to evaluate the clinical relevance of HPV infection and p16-positive OLs.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"7565387"},"PeriodicalIF":2.2,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12868909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effectiveness of Physical Adjunctive Interventions in the Acceleration of Orthodontic Tooth Movement: An Umbrella Review and Meta-Analysis. 物理辅助干预加速正畸牙齿运动的有效性:综述和荟萃分析。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-03 eCollection Date: 2026-01-01 DOI: 10.1155/ijod/9131541
Mohamad Radwan Sirri, Mohammad Osama Namera, Mohamad Yaman Salahi Alasbahi, Salar Karim Khalil

Orthodontic treatment often lasts around 20 months, and prolonged duration increases the risk of adverse events. Physical adjunctive interventions (PAIs) are proposed to accelerate tooth movement, but their efficacy remains uncertain. This umbrella review synthesized systematic reviews and meta-analyses of randomized clinical trials (RCTs) on PAIs published through March 2025 (PubMed, Web of Science, Scopus, Cochrane Library). Review quality was appraised with the A Measurement Tool to Assess Systematic Reviews-2 (AMSTAR-2) and the Risk of Bias in Systematic Reviews (ROBIS) tools. Study overlap was quantified using the corrected Graphical Representation of Overlap for Overviews (GROOVE) method. Risk of bias in the primary studies was reassessed, when required, using the Cochrane Risk of Bias 2 (RoB 2) tool. Certainty of evidence was rated with the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. Random-effects models were used when statistical heterogeneity was substantial (I 2 > 50%); otherwise, fixed-effects models were used. Effect estimates are reported as mean difference (MD) with 95% confidence intervals (CIs). Seventeen systematic reviews (12 meta-analyses, 5 narrative) covering 76 RCTs were included. Vibration devices showed minimal or no clinically significant acceleration: leveling/alignment MD = 0.05 mm (95% CI: -0.38 to 0.49), canine retraction + 0.27 mm/month (95% CI: 0.19-0.35), en-masse retraction + 0.19 mm/month (95% CI: -0.25 to 0.63) (GRADE: moderate-very low). Low-level laser therapy (LLLT) shortened alignment by -58.4 days (95% CI: -88.6 to -28.2) and, in maxillary extraction, by -28 days (95% CI: -39 to -17), with early canine retraction gains (95% CI: +0.31 to +0.27 mm/month) (GRADE: moderate-very low). Light-emitting diode (LED) therapy showed + 0.005 mm/day (95% CI: -0.001 to 0.012) with small, non-significant monthly estimates (GRADE: low-very low). Bioelectric stimulation (BES) added + 1.78 mm at 3 months (95% CI: 0.99-2.57) (GRADE: low). Overall, methodological quality varied widely, with most reviews rated low to critically low by AMSTAR-2 and at high risk of bias by ROBIS. Vibration should not be the primary accelerator. Photobiomodulation (PBM) is the most promising clinical option, but it requires standardized protocols (wavelength, dose, schedule). BES is promising yet underpowered. Registration: PROSPERO CRD420251043659.

正畸治疗通常持续20个月左右,持续时间过长会增加不良事件发生的风险。物理辅助干预(PAIs)被提出来加速牙齿运动,但其效果仍不确定。本综述综合了截至2025年3月发表的PAIs随机临床试验(rct)的系统综述和荟萃分析(PubMed, Web of Science, Scopus, Cochrane Library)。采用评估系统评价的测量工具-2 (AMSTAR-2)和系统评价偏倚风险(ROBIS)工具对评价质量进行评价。使用校正的总体重叠图形表示(GROOVE)方法对研究重叠进行量化。必要时,使用Cochrane风险偏倚2 (RoB 2)工具重新评估初步研究的偏倚风险。证据的确定性采用推荐评估、发展和评价分级(GRADE)方法进行评级。当统计异质性较大时,采用随机效应模型(2 ~ 50%);否则,使用固定效应模型。效应估计以95%置信区间(ci)的平均差(MD)报告。纳入了17篇系统综述(12篇荟萃分析,5篇叙述性综述),涵盖76项随机对照试验。振动装置显示最小或没有临床显著的加速:调平/对齐MD = 0.05 mm (95% CI: -0.38至0.49),犬只缩回+ 0.27 mm/月(95% CI: 0.19至0.35),整体缩回+ 0.19 mm/月(95% CI: -0.25至0.63)(等级:中等-极低)。低水平激光治疗(LLLT)缩短了-58.4天(95% CI: -88.6至-28.2),上颌拔牙缩短了-28天(95% CI: -39至-17),早期犬齿内收(95% CI: +0.31至+0.27 mm/月)(等级:中等-极低)。发光二极管(LED)治疗显示+ 0.005 mm/天(95% CI: -0.001至0.012),每月估计值较小,不显著(GRADE:低-非常低)。生物电刺激(BES)在3个月时增加了1.78 mm (95% CI: 0.99-2.57) (GRADE: low)。总体而言,方法学质量差异很大,大多数评价被AMSTAR-2评为低至极低,被ROBIS评为高偏倚风险。振动不应该是主要的加速器。光生物调节(PBM)是最有前途的临床选择,但它需要标准化的方案(波长,剂量,时间表)。BES很有前途,但动力不足。报名:普洛斯彼罗CRD420251043659。
{"title":"The Effectiveness of Physical Adjunctive Interventions in the Acceleration of Orthodontic Tooth Movement: An Umbrella Review and Meta-Analysis.","authors":"Mohamad Radwan Sirri, Mohammad Osama Namera, Mohamad Yaman Salahi Alasbahi, Salar Karim Khalil","doi":"10.1155/ijod/9131541","DOIUrl":"10.1155/ijod/9131541","url":null,"abstract":"<p><p>Orthodontic treatment often lasts around 20 months, and prolonged duration increases the risk of adverse events. Physical adjunctive interventions (PAIs) are proposed to accelerate tooth movement, but their efficacy remains uncertain. This umbrella review synthesized systematic reviews and meta-analyses of randomized clinical trials (RCTs) on PAIs published through March 2025 (PubMed, Web of Science, Scopus, Cochrane Library). Review quality was appraised with the A Measurement Tool to Assess Systematic Reviews-2 (AMSTAR-2) and the Risk of Bias in Systematic Reviews (ROBIS) tools. Study overlap was quantified using the corrected Graphical Representation of Overlap for Overviews (GROOVE) method. Risk of bias in the primary studies was reassessed, when required, using the Cochrane Risk of Bias 2 (RoB 2) tool. Certainty of evidence was rated with the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. Random-effects models were used when statistical heterogeneity was substantial (<i>I</i> <sup>2</sup> > 50%); otherwise, fixed-effects models were used. Effect estimates are reported as mean difference (MD) with 95% confidence intervals (CIs). Seventeen systematic reviews (12 meta-analyses, 5 narrative) covering 76 RCTs were included. Vibration devices showed minimal or no clinically significant acceleration: leveling/alignment MD = 0.05 mm (95% CI: -0.38 to 0.49), canine retraction + 0.27 mm/month (95% CI: 0.19-0.35), en-masse retraction + 0.19 mm/month (95% CI: -0.25 to 0.63) (GRADE: moderate-very low). Low-level laser therapy (LLLT) shortened alignment by -58.4 days (95% CI: -88.6 to -28.2) and, in maxillary extraction, by -28 days (95% CI: -39 to -17), with early canine retraction gains (95% CI: +0.31 to +0.27 mm/month) (GRADE: moderate-very low). Light-emitting diode (LED) therapy showed + 0.005 mm/day (95% CI: -0.001 to 0.012) with small, non-significant monthly estimates (GRADE: low-very low). Bioelectric stimulation (BES) added + 1.78 mm at 3 months (95% CI: 0.99-2.57) (GRADE: low). Overall, methodological quality varied widely, with most reviews rated low to critically low by AMSTAR-2 and at high risk of bias by ROBIS. Vibration should not be the primary accelerator. Photobiomodulation (PBM) is the most promising clinical option, but it requires standardized protocols (wavelength, dose, schedule). BES is promising yet underpowered. Registration: PROSPERO CRD420251043659.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"9131541"},"PeriodicalIF":2.2,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12868923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A New Classification System to Determine Posterior Mandible Morphology for Implant Therapy. 一种确定种植治疗后颌骨形态的新分类系统。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-01 eCollection Date: 2026-01-01 DOI: 10.1155/ijod/3244223
Faisal Alqaood, Jahanzeb Chaudhry, Amar Hassan Khamis, Keyvan Moharamzadeh, Moosa Abdulla Abuzayeda

Background: We studied the posterior mandibular morphology to develop a new alveolar ridge morphology classification system for implant therapy. Current classification systems do not adequately address essential parameters such as the influence of lingual undercut on implant placement. They do not fully consider clinically important factors such as the shape of the alveolar ridge, the depth and angle of the lingual concavity, and the position of the inferior alveolar canal (IAC). This study was based on an existing classification system and culminated in the development of a new CPD classification system, with a primary focus on lingual concavity.

Material and methods: One hundred and ninety-five patients aged above 19 to over 70 years were included in this cross-sectional study. Cone-beam computed tomography (CBCT) volumes of 90 males and 105 females were analyzed to determine the width of the alveolar bone at the crest (Wc), width of the alveolar bone at the base (Wb), alveolar ridge height (Vcb), alveolar bone height below the Point P (Vb), alveolar bone height above the Point P (Vc), and lingual concavity depth and angle. These parameters were selected to determine the ridge shape and the presence/absence of an undercut. These values were also analyzed in relation to age, gender, presence/absence of the first molar, and presence/absence of the lingual concavity.

Results: The U-type (undercut) ridge was the most common (54.4% left; 52.1% right), followed by the P-type (parallel; 27.2% left; 33.5% right) and the C-type (convergent; 18.5% left; 14.4% right). Alveolar ridge height was correlated with age, gender, ridge type, presence of the first molar, and presence of an undercut. The width of the alveolar bone at the crest correlated with the presence of the first molar and ridge type. The lingual concavity depth correlated with the presence of the first molar, undercut, and ridge type.

Conclusions: We have developed and validated a new and comprehensive CPDU classification system for assessing the posterior mandible to enhance preoperative assessment for implant therapy by categorizing the alveolar ridge morphology into C-type, P-type, and D-type with or without undercut (U) based on the ridge shape, lingual concavity depth and angle, and IAC position.

背景:我们对下颌后牙形态进行了研究,以建立一个新的牙槽嵴形态分类系统,用于种植治疗。目前的分类系统并没有充分解决一些重要的参数,如舌侧凹对种植体放置的影响。他们没有充分考虑临床重要因素,如牙槽嵴的形状、舌凹的深度和角度以及下牙槽管(IAC)的位置。这项研究是基于现有的分类系统,并最终发展了一个新的CPD分类系统,主要关注舌凹性。材料与方法:本横断面研究纳入195例年龄在19岁以上至70岁以上的患者。对90例男性和105例女性的锥形束ct (Cone-beam computed tomography, CBCT)体积进行分析,确定牙槽骨嵴宽度(Wc)、牙槽骨基部宽度(Wb)、牙槽嵴高度(Vcb)、P点以下牙槽骨高度(Vb)、P点以上牙槽骨高度(Vc)以及舌凹深度和角度。选择这些参数来确定脊形和有无凹边。我们还分析了这些数值与年龄、性别、第一磨牙是否存在以及舌凹是否存在的关系。结果:u型(下凹型)嵴最常见(左占54.4%,右占52.1%),其次是p型(平行,左占27.2%,右占33.5%)和c型(会聚,左占18.5%,右占14.4%)。牙槽嵴高度与年龄、性别、牙槽嵴类型、是否有第一磨牙以及是否有下切有关。牙槽骨嵴的宽度与第一磨牙的存在和脊型相关。舌凹深度与第一磨牙、下凹和脊型的存在相关。结论:我们开发并验证了一种新的、全面的CPDU分类系统,用于评估后下颌,通过根据牙槽嵴形状、舌凹深度和角度以及IAC位置将牙槽嵴形态分为c型、p型和d型,有无凹边(U),以加强种植治疗的术前评估。
{"title":"A New Classification System to Determine Posterior Mandible Morphology for Implant Therapy.","authors":"Faisal Alqaood, Jahanzeb Chaudhry, Amar Hassan Khamis, Keyvan Moharamzadeh, Moosa Abdulla Abuzayeda","doi":"10.1155/ijod/3244223","DOIUrl":"10.1155/ijod/3244223","url":null,"abstract":"<p><strong>Background: </strong>We studied the posterior mandibular morphology to develop a new alveolar ridge morphology classification system for implant therapy. Current classification systems do not adequately address essential parameters such as the influence of lingual undercut on implant placement. They do not fully consider clinically important factors such as the shape of the alveolar ridge, the depth and angle of the lingual concavity, and the position of the inferior alveolar canal (IAC). This study was based on an existing classification system and culminated in the development of a new CPD classification system, with a primary focus on lingual concavity.</p><p><strong>Material and methods: </strong>One hundred and ninety-five patients aged above 19 to over 70 years were included in this cross-sectional study. Cone-beam computed tomography (CBCT) volumes of 90 males and 105 females were analyzed to determine the width of the alveolar bone at the crest (Wc), width of the alveolar bone at the base (Wb), alveolar ridge height (Vcb), alveolar bone height below the Point P (Vb), alveolar bone height above the Point P (Vc), and lingual concavity depth and angle. These parameters were selected to determine the ridge shape and the presence/absence of an undercut. These values were also analyzed in relation to age, gender, presence/absence of the first molar, and presence/absence of the lingual concavity.</p><p><strong>Results: </strong>The U-type (undercut) ridge was the most common (54.4% left; 52.1% right), followed by the P-type (parallel; 27.2% left; 33.5% right) and the C-type (convergent; 18.5% left; 14.4% right). Alveolar ridge height was correlated with age, gender, ridge type, presence of the first molar, and presence of an undercut. The width of the alveolar bone at the crest correlated with the presence of the first molar and ridge type. The lingual concavity depth correlated with the presence of the first molar, undercut, and ridge type.</p><p><strong>Conclusions: </strong>We have developed and validated a new and comprehensive CPDU classification system for assessing the posterior mandible to enhance preoperative assessment for implant therapy by categorizing the alveolar ridge morphology into C-type, P-type, and D-type with or without undercut (U) based on the ridge shape, lingual concavity depth and angle, and IAC position.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"3244223"},"PeriodicalIF":2.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12862232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146113194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Journal of Dentistry
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1