International Journal of Dentistry最新文献

Purpose: The aim of this comparative observational study is to evaluate and compare the size and position of the condyle among male and female patients with different skeletal patterns in the anterior-posterior dimension using cone beam computed tomography (CBCT) images. Materials and Methods: CBCT images of 120 patients, all prepared for other treatment purposes under the same conditions, were included in the study. The patients were classified into three groups-class I, class II, and class III-based on ANB angles and Wits analysis. The size of the condyle was measured in terms of width, height, and length. The position of the condyle was assessed by measuring the superior joint space (SS), anterior joint space (AS), and posterior joint space (PS) on the right and left sides separately. The measurements and results were analyzed using analysis of covariance (ANCOVA) and Bonferroni analysis. A statistical significance level of p  < 0.05 was considered. Results: The study found no statistically significant differences in the size of the SS and AS (p = 0.481 and p = 0.392, respectively) across different skeletal patterns. However, the size of the PS was significantly greater in class I subjects compared to class III subjects (p = 0.015). There were no statistically significant differences in condyle height and width among the different skeletal patterns (p = 0.367 and p = 0.720, respectively). In contrast, condyle length was statistically significant in class II individuals (p = 0.002) and was the lowest among the other skeletal pattern groups. Conclusions: Based on the results obtained, class I individuals have lower PS values compared to class III individuals. Additionally, class II individuals have shorter condyle lengths compared to those in class III and class I.

Objective: The successful management of necrotic pulps and apical periodontitis poses a tough challenge in endodontic therapy, as it involves addressing compromised tooth vitality and microbial invasion of root canal systems. Failure to effectively treat these conditions can lead to persistent infection and severe patient discomfort. The efficacy of double antibiotic paste (DAP), a mixture of ciprofloxacin and metronidazole, was evaluated and compared to calcium hydroxide (CH) by assessing radiographic and clinical outcomes of nonsurgical endodontic treatment in cases with necrotic pulps and the presence of apical periodontitis. Methods: Thirty maxillary anterior teeth with necrotic pulps and apical periodontitis (periapical index [PAI] = 5) were divided randomly into two experimental groups. The first group received CH dressing, while the other group filled with DAP as intracanal medicament. After 3 weeks, medicaments were removed, and teeth were obturated in both groups. Teeth were assessed clinically and radiographically at 6-month and 12-month follow-ups. A chi-square test was performed to compare the outcome between the groups. Results: None of the teeth showed complete healing in a 6-month follow-up. At the 12-month follow-up, six samples in the DAP group showed complete healing of the periapical (PA) lesion, while none of the samples in the CH group were completely healed. The PA healing outcome was as follows: in the DAP group, 40% of cases were healed, 60% healing, and 0% diseased, while in the CH group, 0% healed, 93.3% healing, and 6.7% diseased. The results of the two experimental groups in 12 months differed significantly (p  < 0.05). Conclusion: DAP group has shown significantly better outcomes compared to CH as intracanal medicament in the treatment of teeth with PA lesions. This finding suggests that DAP may offer a more effective therapeutic approach in managing necrotic pulps and apical periodontitis, potentially improving patient outcomes and treatment success rates. Trial Registration: Clinical Trial Registry identifier: IRCT2015060822615N1.

Background: XP-endo files are composed of Max-Wire alloy, which was developed by FKG Dentaire (La Chaux-de-Fonds, Switzerland). This alloy, known as Martensite-Austenite Electropolish Flex, is the first NiTi alloy used in endodontics to combine the shape memory effect with superelasticity for use in clinical practice. Objective: This article aims to provide a comprehensive overview of the existing knowledge and evidence regarding different XP-endo files and systems, XP-endo Finisher (XPEF), XP-endo Shaper (XPES), XP-endo Retreatment (XPER), XP-endo Rise (XPE-Rise), and XPE-Rise Retreatment (XPE-Rise-R), to help clinicians understand their different properties and recommended clinical uses. Moreover, this review aims to identify future research opportunities in this field. Materials and Methods: A search was performed in the PubMed database using the keywords "XP endo" or "XP-endo". A total of 309 studies were identified during the initial search, and then initial abstract screening was conducted. The inclusion criteria included any study that aimed to evaluate XP endo files and systems on permanent teeth, either in vivo or in vitro. We excluded studies that were unrelated to the subject, literature reviews, case studies, and studies that employed deciduous teeth. Finally, we performed an extensive review of the selected 130 studies, which we assessed, summarized, and classified based on the specific XP-endo file used. Conclusion: Overall, XP-endo files offer significant improvements in endodontic treatment. XPEF excels in irrigation activation and medicament removal, and XPES succeeds in canal cleaning, shaping, and retreatment. The XPER system, which incorporates the XPEF-R file, shows promise in removing root-filling materials, but its performance is inconsistent compared to other retreatment systems. We have found limited information regarding the latest XPE-Rise and XPE-Rise-R systems, additional research is required to fully determine their comparative effectiveness and optimize their clinical application.

Objective: The correlation between anatomy features of impacted mandibular third molars (M3Ms) and prevalence of pericoronitis was only interpreted using univariate analysis. This study investigated this correlation using multivariable analysis to determine the relationship between pericoronitis prevalence and the M3Ms' anatomical features. Methods: This cross-sectional study recruited 245 patients with 338 impacted M3Ms. One researcher collected participants' demographic characteristics such as sexes, age, side, and pericoronitis condition. The radiographic characteristics of M3Ms, including eruption direction and impacted levels according to Pell-Gregory classification, were assessed based on their orthopantomograms. Initially, univariate analyses were used to determine potential demographic and radiographic factors that correlated to pericoronitis. These factors were, then, analyzes using Firth's logistic regression. Results: No significant difference was found between non- and pericoronitis groups about sexes, age, side (p  > 0.05). The univariate analyses showed that proportion of vertical impacted levels and eruption direction of M3Ms were significantly different between non- and pericoronitis groups. Firth's logistic regression analysis indicated that M3Ms with impacted level A were more likely to suffer from pericoronitis than ones at level B (odds ratio (OR) = 3.34), wheraes M3Ms impacted level II had higher risk of pericorinitis than ones at level I (OR = 1.63). Vertical M3Ms were more likely to develop pericoronitis than horizontal (OR = 5.78) ones. Conclusion: M3M angulation and impacted level are significant factors relating to pericoronitis prevalence. M3Ms with vertical eruption, vertically level A, and horizontally level B are more likely to have pericoronitis.

Objectives: This study aimed to assess the effect of temperature of 1.23% acidulated phosphate fluoride (APF) gel on enamel microhardness of permanent teeth. Materials and Methods: This in vitro experimental study was conducted on 36 surgically extracted impacted human third molars. The teeth were mounted in acrylic resin and mesiodistally sectioned into buccal and lingual halves by a high-speed cutting saw. The buccal halves of the teeth were polished with silicone carbide abrasive paper and subjected to pH cycling (8 h of immersion in demineralizing agent and 16 h of immersion in remineralizing agent) for 10 days. Their primary enamel microhardness was subsequently measured by a Vickers microhardness tester. The specimens were then randomly assigned to three groups (n = 12) for application of 1.23% APF gel at 4, 25, and 37°C for 4 min. The specimens were then rinsed and incubated for 24 h. Their secondary enamel microhardness was subsequently measured, and the change in microhardness of the specimens was calculated and analyzed by one-way analysis of variance (ANOVA; α = 0.05). Results: The mean percentage of change in microhardness was -0.73% ± 16.8%, -5.28% ± 27.32%, and -7.27% ± 32.28% following the application of APF gel at 4, 25, and 37°C, respectively. The difference among the three groups was not significant regarding the percentage of change in microhardness (p  > 0.05). Conclusion: Increasing the temperature of 1.23% APF gel from 4 to 25°C and 37°C did not cause a significant change in enamel microhardness of permanent teeth.

Objective: Bone regeneration plays a pivotal role in modern oral surgery, particularly in facilitating successful implant-prosthetic rehabilitation. This systematic review explores the regenerative potential of growth factors, such as platelet-rich fibrin (PRF) and concentrated growth factors (CGFs), when combined with various types of scaffolds in bone augmentation procedures, including guided bone regeneration, split crest, sinus lift (SL), and alveolar ridge preservation. Method: A comprehensive search strategy yielded 18 relevant studies, which were analyzed for bone formation and stabilization outcomes. Results: Results indicate that PRF enhances bone regeneration and stabilization in SL and ridge augmentation procedures, while CGFs facilitate surgical techniques and augment bone. However, some studies did not report significant differences. Growth factors also demonstrate benefits in wound healing, reducing bone resorption, and enhancing socket preservation. Conclusion: Despite valuable insights, further research is needed to comprehensively understand the characteristics of growth factors in various surgical interventions, ensuring informed decision-making in bone regeneration surgery.

Objective: Despite the plethora of published periodontal interventional and experimental studies, there are no reports evaluating the experience of the participants as a research subject or their willingness for repeat participation in a similar study. This study aimed to determine the participants' experience and willingness to participate again in periodontal experimental studies and to explore factors that affect the participants' research experience. Materials and Methods: Questionnaires from four completed experimental wound healing studies with 76 total participants were extracted and analyzed. The participants answered the same specific questions at their last study visit. The questions asked were "overall experience in the study" and "willingness to participate in the study again," with each question providing five levels/possible answers. Questionnaires also provided an opportunity for participants to offer open-ended comments about their participation. Frequency distribution and logistic regression analyses were performed to evaluate the association between the participant's responses and study characteristics. Results: All 76 participants answered the specific questions. Overall, 88.2% of participants had a positive experience from their research participation, and 65.8% of them would participate again in such a study. Of the 76 participants, 50 were in studies that included multiple (≥2) experimental wounds, while 26 received only a single experimental wound. Participation experience was negatively associated with the number of wounds received (p < 0.001), while willingness to participate again was positively associated with participation experience (p < 0.001). Conclusions: Within the present study limitations, volunteers participating in periodontal experimental studies have an overall positive experience and express willingness for repeat participation.

Objective: The impact of the deep margin elevation (DME) technique and its associated materials on the stress distribution in ceramic endocrowns remains to be fully understood. This finite element analysis (FEA) aimed to assess the effects of flowable composite and resin-modified glass ionomer (RMGI) as DME materials on the maximum Von Mises stress (VMS) values and overall stress distribution within ceramic endocrowns and the surrounding tooth structure. Materials and Methods: A mandibular molar featuring a class II mesio occlusal (MO) cavity with the gingival margin of the mesial cavity positioned 2 mm below the cementoenamel junction (CEJ) was prepared and scanned using a Medit i500 scanner. The digital file was then transferred to computer-aided design (CAD) software to create the models. The study generated four scenarios: an intact tooth model (model of intact tooth (MIT)), a prepared tooth model without a DME layer (model without DME (MWD)), a model with a 2 mm DME layer using composite material (model with DME of composite (MDC)), and a model employing RMGI (model with DME of RMGI (MDR)). Stress distribution under axial loads was evaluated based on the Von Mises criterion. Results: The MIT model demonstrated the highest stress concentration at the CEJ region yet exhibited lower stress levels than others. The MWD model showed the highest stress levels. No significant differences in stress distribution patterns were observed between the MDR and MDC models. All models displayed similar stress distributions in the bone. Conclusion: Regardless of the material used, incorporating a DME layer in cavities extending below the CEJ is advisable to achieve uniform stress distribution. Minimizing tooth preparation and preserving tooth structure are recommended. Clinical Significance: Employing a DME layer in cavities with margins below the CEJ is beneficial for reducing stress, irrespective of the material choice.

Thermophilic bacteria living in extreme areas with high temperatures are capable of producing secondary metabolites, such as antimicrobial peptides (AMPs). AMPs are stable at high temperatures and show good antibacterial activity. Therefore, this study aimed to identify thermophilic bacteria from the crater of Mount Tangkuban Perahu around West Java and assess antibacterial effectiveness of AMPs against Streptococcus mutans, which contribute to oral biofilm formation. The isolate obtained was identified using 16S ribosomal ribonucleic acid (rRNA) gene sequencing, and the supernatant of the isolate was tested against S. mutans American Type Culture Collection (ATCC) 25175 using the disc assay method. To determine AMPs-coding genes, its genome was uploaded to antibiotic and secondary metabolite analysis shell (antiSMASH) 5.0.0 platform and biofilm inhibition was tested using the microtiter plate technique (with a 96-well bottom). Subsequently, the results were assessed using a microplate reader operating at 595 nm wavelength. The isolate was identified as Geobacillus subterraneus, with antibacterial activity against S. mutans, and produced an inhibition zone of 8.40 mm at an optimum pH of 8. The output of AMPs-coding gene showed that AMPs of the isolate were a member of the lanthipeptide class I, or bacteriocin-I group. AMPs of G. subterraneus suppressed the growth of S. mutans biofilm at a supernatant concentration of 5%, with the lowest optical density (OD) value of 0.061 and the highest percentage of biofilm growth inhibition at 28.24%. Based on the results, G. subterraneus derived from the crater of Mount Tangkuban Perahu showed potent antibacterial properties against S. mutans, making it a promising novel S. mutans anti-biofilm candidate.

Background: The study of working conditions and the quality of life (QoL) of medical workers has not lost its relevance worldwide. This highlights the need to understand the many aspects of life that may characterize physician performance and satisfaction with working conditions. This is extremely important for providing quality and safe medical care. This research aims to study dentists' lifestyles and working conditions in the Republic of Kazakhstan and the impact of these indicators on their QoL. Methods: This article presents the results of a cross-sectional survey of a sociological questionnaire conducted with the participation of 254 dentists in Kazakhstan. Results: Only a third of dentists follow a healthy lifestyle. In total, 39% of dentists currently smoke, and 24% drink alcohol. Dentists with more than 20 years of experience have a worse QoL and have the lowest scores in all domains compared to dentists with less experience. The lowest score was scored for mental health (mean = 51.81). On all scales, dentists who worked more than 40 h a week reported decreased QoL; the lowest score was in the "mental health" domain (mean = 52.80). Conclusion: The QoL of dentists in Kazakhstan is negatively affected by their working hours and long working experience. Measures are necessary to improve their working conditions, work schedule planning, and mental health.