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OHIP-14 Scores in Patients with Sjögren's Syndrome Compared to Sicca Syndrome: A Systematic Review with Meta-Analysis. 斯约格伦综合征患者的 OHIP-14 评分与虹膜睫状体综合征患者的 OHIP-14 评分比较:系统回顾与元分析。
IF 2.1 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-09 eCollection Date: 2024-01-01 DOI: 10.1155/2024/9277636
Rossana Izzetti, Elisabetta Carli, Stefano Gennai, Filippo Graziani, Marco Nisi

Objectives: Primary Sjögren's syndrome (pSS) is a chronic autoimmune disorder characterized by dryness of mucous membranes, predominantly the eyes and mouth, following glandular tissue substitution. The onset of oral dryness constitutes a significant source of discomfort that negatively affects overall quality of life. This systematic review aimed at investigating the differences in Oral Health Impact Profile-14 (OHIP-14) questionnaire scores in patients diagnosed with Sjögren's syndrome compared to sicca syndrome, to assess the influence of the two conditions on oral health. Study Design. A systematic electronic and manual search was performed up to December 2023 for studies reporting OHIP-14 questionnaire scores in pSS patients versus sicca syndrome. Two authors independently reviewed, selected, and extracted the data. The outcome was the assessment of OHIP-14 scores in studies comparing pSS- and sicca syndrome-affected patients. Meta-analysis was conducted on available quantitative data.

Results: Literature search retrieved 30 articles, and 3 articles met the criteria for inclusion in the review. Meta-analysis revealed significantly higher scores in patients with sicca syndrome compared to pSS, although salivary flow was markedly reduced in pSS.

Conclusions: While offering supplementary information to standard tests and supporting the assessment of pSS and sicca syndrome patients, further validation is necessary to establish OHIP-14 validity in determining the impact of pSS and sicca syndrome on patients' quality of life.

目的:原发性斯约格伦综合征(pSS)是一种慢性自身免疫性疾病,其特点是腺组织替代后出现粘膜(主要是眼睛和口腔)干燥。口腔干燥症的出现会给患者带来严重的不适感,对整体生活质量产生负面影响。本系统性综述旨在调查被诊断为斯尤格林综合征的患者与疱疹综合征患者在口腔健康影响档案-14(OHIP-14)问卷中得分的差异,以评估这两种疾病对口腔健康的影响。研究设计。截至 2023 年 12 月,我们通过电子和人工检索的方式,系统地检索了报告 PSS 患者 OHIP-14 问卷得分与 Sjögren's 综合征患者 OHIP-14 问卷得分的研究。两位作者独立审查、筛选和提取数据。研究结果是在比较 pSS 患者和筛查综合征患者的研究中对 OHIP-14 评分进行评估。对现有的定量数据进行了元分析:文献检索共检索到 30 篇文章,其中 3 篇符合纳入综述的标准。Meta 分析显示,与 pSS 相比,sicca 综合征患者的评分明显更高,但 pSS 患者的唾液流量明显减少:尽管OHIP-14为标准测试提供了补充信息,并支持对pSS和sicca综合征患者进行评估,但仍有必要进行进一步验证,以确定OHIP-14在确定pSS和sicca综合征对患者生活质量的影响方面的有效性。
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引用次数: 0
The Morphology of Peri-Implantitis Bone Defects: A Retrospective Study on Periapical Radiographs. 牙周炎骨缺损的形态:根尖周X光片回顾性研究
IF 2.1 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.1155/2024/4324114
Alice Alberti, Benedetta Morandi, Caterina Frascolino, Nicolo Cavalli, Luca Francetti, Stefano Corbella

Objectives: The aims of this study were to assess the morphologic features of peri-implant defects, as measured on 2D intraoral radiographs, and to investigate the possible correlation between such morphology and other parameters related to the position and characteristics of the implant or the implant-supported prosthesis.

Materials and methods: Implants with peri-implantitis were included in this retrospective study. Data collected were related both to the patients and to the position/characteristics of the implants and the implant-supported prosthesis. Measurements of the morphologic defects were performed by two operators on digitalized intraoral periapical radiographs. Results and Conclusion. In total, 73 implants in 27 patients were included. The measurements of the periapical radiograph suggested that the most common defect conformation was crateriform, with both intraosseous and horizontal components. An inverse correlation was found between the extension of the peri-implant lesion and the time between the radiographic assessment and the implant placement. The total lesion area was strongly correlated to oral hygiene levels. No correlations between lesion extension and smoking, diabetes, history of periodontal were found. In conclusion, the results from this 2D radiographic study showed the prevalence of crateriform peri-implant defects, with a hygiene-correlated extension, perceptible on the mesial and distal aspects; 3D imaging could be used when available for further research and clinical investigation.

研究目的本研究的目的是根据口内二维X光片的测量结果,评估种植体周围缺损的形态特征,并研究这种形态与种植体或种植体支持修复体的位置和特征相关的其他参数之间可能存在的关联:这项回顾性研究纳入了患有种植体周围炎的种植体。收集的数据既与患者有关,也与种植体和种植体支持修复体的位置/特征有关。由两名操作员对数字化口内根尖周X光片进行形态缺陷测量。结果和结论。共纳入了 27 名患者的 73 个种植体。根尖周X光片的测量结果表明,最常见的缺损形态是火山口状,既有骨内缺损,也有水平缺损。研究发现,种植体周围病变的扩展程度与放射学评估和种植体植入之间的时间呈反比。病变总面积与口腔卫生水平密切相关。病变范围的扩大与吸烟、糖尿病、牙周病史之间没有相关性。总之,这项二维影像学研究结果表明,火山口状的种植体周围缺损非常普遍,其扩展与卫生状况有关,在中轴和远轴均可观察到;在有条件的情况下,可以使用三维成像技术进行进一步的研究和临床调查。
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引用次数: 0
Improvement of Quality of Life after Surgical Treatment of Patients with MRONJ: A Prospective Analysis Using the SF-12 and OHIP-14 Questionnaires. MRONJ 患者手术治疗后生活质量的改善:使用 SF-12 和 OHIP-14 问卷的前瞻性分析。
IF 2.1 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.1155/2024/4435791
Georg Hoene, Nikolaus von Hahn, Denise Sievers, Lukas Schuffelen, Susanne Wolfer, Kathi Goldstein, Boris Schminke, Phillipp Brockmeyer, Philipp Kauffmann

Background: Medication-related osteonecrosis of the jaw (MRONJ) is a rare, serious, and debilitating disease of unknown cause that can be associated with significant health-related quality of life (HRQOL) impairment. Hematological disease is characterized by a nonhealing exposed jawbone in patients with a history of antiresorptive or antiangiogenic agent use without radiation exposure to the head or neck. Patients and Materials and Methods. This prospective study over the period from May 2020 to December 2021 included a representative sample consisting of 27 patients with at least stage 2 MRONJ lesions who underwent surgical rehabilitation via oral and maxillofacial surgery at the University Medical Center Göttingen, Germany. Quality of life data were collected over a 6-month postoperative period using the Health-Related QOL (SF-12) and Oral Health-Related QOL (OHIP-14) questionnaires.

Results: A total of 27 patients considered in the study had a total of 42 MRONJ lesions, corresponding to a mean of 1.56 necroses per patient. MRONJ lesions were downstaged in 85% of the patients. HRQOL was evaluated with the SF-12 questionnaire. Significant improvements were found in six of the eight categories (General Health (p  < 0.001), Bodily Pain (p < 0.001), Mental Health (p < 0.001), Vitality (p  < 0.001), Role-Emotional (p=0.028), and Social Functioning (p=0.031)). The OHRQOL score also improved significantly after surgical intervention (p < 0.001).

Conclusion: With completed surgical therapy, improvements in HRQOL and OHRQOL are measurable.

背景:药物相关性颌骨坏死(MRONJ)是一种罕见的、严重的、使人衰弱的疾病,病因不明,可导致与健康相关的生活质量(HRQOL)严重受损。血液病的特点是患者的颌骨外露不愈合,患者有抗骨质吸收剂或抗血管生成剂的使用史,但头部或颈部未受到放射线照射。患者、材料和方法。这项前瞻性研究的时间跨度为 2020 年 5 月至 2021 年 12 月,研究对象包括在德国哥廷根大学医学中心口腔颌面外科接受手术康复治疗的 27 名至少患有二期 MRONJ 病变的患者。研究人员使用健康相关QOL(SF-12)和口腔健康相关QOL(OHIP-14)问卷收集了术后6个月的生活质量数据:本研究共考虑了 27 名患者,他们共有 42 处 MRONJ 病变,平均每位患者有 1.56 处坏死。85%的患者的MRONJ病变被降级。HRQOL 采用 SF-12 问卷进行评估。在八个类别中的六个类别(一般健康(p < 0.001)、身体疼痛(p < 0.001)、心理健康(p < 0.001)、活力(p < 0.001)、角色情感(p=0.028)和社会功能(p=0.031))都有显著改善。手术干预后,OHRQOL评分也有明显改善(p < 0.001):结论:完成手术治疗后,患者的 HRQOL 和 OHRQOL 均有明显改善。
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引用次数: 0
Fracture Resistance of Simulated Immature Teeth Filled with Three Types of Calcium Silicate Cement after Intracanal Medication with Ca(OH)2: An Ex Vivo Study. 用 Ca(OH)2 树液进行龈内注射后,用三种硅酸钙水泥填充的模拟未成熟牙齿的抗折断性:体外研究。
IF 2.1 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-26 eCollection Date: 2024-01-01 DOI: 10.1155/2024/8386533
Kuttalee Sriprasart, Suwit Wimonchit

Objectives: The aim of this study was to evaluate the 1-day fracture resistance of simulated immature teeth with an apical plug with ProRoot MTA, MTA Angelus, and RetroMTA after calcium hydroxide intracanal medication.

Materials and methods: Sixty extracted, single-rooted human mandibular premolars were randomly divided into six groups of 10 teeth each. Firstly, to standardize the 9 mm root length, the crowns were cut off at and 9 mm below the cementoenamel junction transversely. Simulations for immature apices were carried out by using No. 1-6 Peeso reamers to pass through the apex to obtain a diameter of 1.7 mm at the apical opening. One group served as a negative control without any treatment, while the other groups received 30 days of calcium hydroxide intracanal medication. Four groups were plugs with 4 mm of ProRoot MTA, MTA Angelus, RetroMTA, and gutta-percha, respectively. The last one was served as a positive control group without filling inside. After 1 day of incubation, specimens were vertically loaded in a universal testing machine at a crosshead speed of 1 mm/min until fracture occurred. The peak load to fracture (Newton) and fracture pattern were recorded. A one-way analysis of variance (ANOVA) followed by Tukey's HSD test was used for data analysis.

Results: The highest mean load to fracture was shown in the negative control group (543.33 ± 37.17 N), followed by ProRoot MTA (432.82 ± 68.06 N), MTA Angelus (396.92 ± 59.93 N), RetroMTA (389.08 ± 56.25 N), and gutta-percha (283.28 ± 43.40 N), and the lowest belonged to the positive control group (239.98 ± 27.19 N). The significant differences were found between both the control and experimental groups with an apical plug with calcium silicate cement (p  < 0.05). There were no significant differences among those three apical plugs (p  > 0.05).

Conclusion: Apical plugs with ProRoot MTA, MTA Angelus, and RetroMTA had an immediate strengthening effect on simulated immature teeth after calcium hydroxide intracanal medication had been used.

研究目的本研究的目的是评估使用 ProRoot MTA、MTA Angelus 和 RetroMTA 进行根尖封闭的模拟未成熟牙齿在氢氧化钙根管治疗后 1 天的抗折性:将拔出的 60 颗单根人类下颌前磨牙随机分为六组,每组 10 颗。首先,为了标准化 9 毫米的牙根长度,在牙本质釉质交界处和下 9 毫米处横向切断牙冠。使用 1-6 号 Peeso 铰刀穿过根尖,以获得根尖开口处 1.7 毫米的直径,从而对未成熟根尖进行模拟。一组作为阴性对照,不做任何处理,其他各组接受 30 天的氢氧化钙根管治疗。四组分别塞入 4 毫米的 ProRoot MTA、MTA Angelus、RetroMTA 和古塔胶。最后一组为阳性对照组,内部无填充物。培养 1 天后,在万能试验机中以 1 毫米/分钟的十字头速度垂直加载试样,直至发生断裂。记录断裂峰值载荷(牛顿)和断裂形态。数据分析采用单因素方差分析(ANOVA),然后进行Tukey's HSD检验:结果:阴性对照组的平均骨折载荷最高(543.33 ± 37.17 N),其次是 ProRoot MTA(432.82 ± 68.06 N)、MTA Angelus(396.92 ± 59.93 N)、RetroMTA(389.08 ± 56.25 N)和古塔波胶(283.28 ± 43.40 N),最低的是阳性对照组(239.98 ± 27.19 N)。使用硅酸钙水门汀根尖塞的对照组和实验组之间存在明显差异(P < 0.05)。结论:结论:ProRoot MTA、MTA Angelus 和 RetroMTA 根尖塞在使用氢氧化钙根管内药物后,对模拟未成熟牙具有即时强化效果。
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引用次数: 0
Studying and Characterization of Coating of Zein-CaSiO3 Composite on Polyetheretherketone Implant Material. 聚醚醚酮种植体材料上 Zein-CaSiO3 复合材料涂层的研究与表征
IF 2.1 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-16 eCollection Date: 2024-01-01 DOI: 10.1155/2024/1592439
Sama Abdulrazzaq, Thekra Ismael Hamad

Material-coated implants are placed in the bone and play an essential role in bone regeneration and rapid healing around implants. Polymeric matrix reinforced with ceramic materials is a promising composite material for coating implants. This study aims to determine the effect of mixing various concentrations of zein with CaSiO3 on polyetheretherketone (PEEK) as implant material. The coating was performed using the electrospray method. PEEK disks were used as a control group. The coated disks with different concentrations of zein-CaSiO3 (Group 1: 10% wt, 90% wt), (Group 2: 20% wt, 80% wt), and (Group 3%: 30% wt, 70% wt) were the experimental group. Each group was characterized by atomic force microscopy, field emission scanning electron microscope, Fourier-transform infrared spectroscopy, water contact angle, and adhesion strength. The lowest water contact angle was obtained for Group 1: 10% wt and 90% wt were (26.64° and 27.13°, respectively), and increasing amounts of zein in comparison to quantities of CaSiO3 resulted in increased adhesion strength of the composite material to the substrate. The current study suggested that the higher amount of zein compared to the amount of CaSiO3 mixture coating is achieved by electrospraying, a favorable candidate for coating implants compared to uncoated and coated disks with low concentrations of zein compared to concentrations of CaSiO3.

材料涂层植入物被植入骨内,对植入物周围的骨再生和快速愈合起着至关重要的作用。用陶瓷材料增强的聚合物基质是一种很有前景的涂层植入物复合材料。本研究旨在确定不同浓度的玉米蛋白与 CaSiO3 混合对作为植入材料的聚醚醚酮(PEEK)的影响。涂层采用电喷雾法进行。PEEK 盘作为对照组。不同浓度的玉米蛋白-CaSiO3涂层盘(第 1 组:10% wt、90% wt)、(第 2 组:20% wt、80% wt)和(第 3 组:30% wt、70% wt)为实验组。各组分别用原子力显微镜、场发射扫描电子显微镜、傅立叶变换红外光谱、水接触角和附着强度进行了表征。第 1 组:10% wt 和 90% wt 的水接触角最小(分别为 26.64° 和 27.13°),与 CaSiO3 的用量相比,玉米蛋白用量的增加会提高复合材料与基底的粘附强度。目前的研究表明,与 CaSiO3 混合物的用量相比,通过电喷雾实现的玉米蛋白用量更高,与未涂层和玉米蛋白浓度低于 CaSiO3 浓度的涂层盘相比,玉米蛋白是涂层植入物的有利候选材料。
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引用次数: 0
Exploring the Challenges in Covering Dental Services through Complementary Insurance in Iran: A Qualitative Study. 探索伊朗通过补充保险覆盖牙科服务所面临的挑战:定性研究。
IF 2.1 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-11 eCollection Date: 2024-01-01 DOI: 10.1155/2024/6982460
Zahra Pouraskari, Reza Yazdani, Hossein Hessari

Background: Financial protection is crucial for attaining universal health coverage. The inclusion of costly dental services in insurance plans poses a significant challenge for all parties involved in the insurance sector. This study aimed to investigate the challenges of covering dental services by complementary insurance in Iran during 2020-2021.

Materials and methods: This qualitative research was conducted in Iran during 2020-2021. A triangulation of methods and data sources were employed to achieve a comprehensive perspective. In-depth semistructured interviews were conducted on an individual basis, and all national documents, rules, regulations, and instructions pertaining to complementary dental insurance were thoroughly reviewed. Purposeful sampling was used to select participants from all stakeholder groups engaged in dental insurance coverage, including (1) health system policymakers, (2) insurers, (3) policyholders, (4) care providers (dentists), and (5) insured people. Six open-ended questions were formulated to explore various facets of dental insurance, including (1) development, (2) management, (3) population coverage, (4) premium calculation, (5) services coverage, and (6) payment and reimbursement mechanisms. With the consent of the participants, all interviews were recorded and transcribed verbatim. The gathered data were evaluated using a framework analysis approach in the MAXQDA20 software. Finally, the primary themes, each encompassing multiple subthemes, were identified and presented.

Results: A total of 26 interviews were conducted with five groups of interviewees, and nine national documents were evaluated. Six themes were extracted, which included 18 codes from the interviews and seven codes from the documents. The extracted themes were as follows: (1) Insurance commitments and service coverage, (2) reimbursement system, (3) information system, (4) economic issues, (5) population coverage, and (6) regulation and supervision. The high cost of dental services was the most frequent challenge, followed by the insurance commitments and service coverage.

Conclusions: The delivery of dental services through complementary insurance in Iran primarily faces economic and service coverage challenges. The resolution hinges on the collaboration between basic and complementary insurance sectors, the development of a unified information system for insured individuals, and the implementation of a risk-adjusted premium plan.

背景:财政保障对于实现全民医保至关重要。将昂贵的牙科服务纳入保险计划对保险行业的所有相关方都是一个重大挑战。本研究旨在调查 2020-2021 年期间伊朗补充保险覆盖牙科服务所面临的挑战:这项定性研究于 2020-2021 年期间在伊朗进行。为了获得全面的视角,研究采用了多种方法和数据来源。以个人为基础进行了深入的半结构式访谈,并全面审查了与补充牙科保险有关的所有国家文件、法规、规章和指示。我们采用了有目的的抽样方法,从参与牙科保险的所有利益相关群体中挑选参与者,包括:(1)医疗系统政策制定者;(2)保险公司;(3)保单持有人;(4)医疗服务提供者(牙医);(5)被保险人。为了探究牙科保险的各个方面,我们制定了六个开放式问题,包括(1)发展,(2)管理,(3)人口覆盖,(4)保费计算,(5)服务覆盖,以及(6)支付和报销机制。在征得参与者同意后,所有访谈都进行了录音和逐字记录。收集到的数据使用 MAXQDA20 软件的框架分析方法进行评估。最后,确定并提出了主要主题,每个主题都包含多个次主题:共对五组受访者进行了 26 次访谈,并对九份国家文件进行了评估。从访谈中提取了 18 个代码,从文件中提取了 7 个代码,共提炼出 6 个主题。提取的主题如下(1) 保险承诺和服务覆盖,(2) 补偿制度,(3) 信息系统,(4) 经济问题,(5) 人口覆盖,(6) 监管和监督。牙科服务的高成本是最常见的挑战,其次是保险承诺和服务覆盖面:结论:伊朗通过补充保险提供牙科服务主要面临经济和服务覆盖面的挑战。解决这一问题的关键在于基本保险和补充保险部门之间的合作、为投保人开发统一的信息系统以及实施风险调整保费计划。
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引用次数: 0
Analysis of Physical and Mechanical Properties of Universal Composites under Different Types of Polishing before and after Acid Challenge. 酸挑战前后不同抛光类型下通用复合材料的物理和机械性能分析
IF 1.9 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-02-29 eCollection Date: 2024-01-01 DOI: 10.1155/2024/6817593
José Roberto Vergínio de Matos, Letícia Barbero Antunes, Isabela Araguê Catanoze, Isabela Saturnino de Souza, Paulo Henrique Dos Santos, Aimée Maria Guiotti

This study aimed to evaluate in vitro the degree of surface smoothness provided by two different polishing techniques and the effect of acid challenge on the alteration of surface roughness (Ra), microhardness (Knoop), and color (ΔE00) of three nanoparticulate composites, simulating 1 year of exposure to hydrochloric acid (HCl). Eighty specimens for each composite were divided into four groups (n = 240), being control without polishing, control with wear, WPC (wear + polishing with Cosmedent Kit), and WPB (wear + BisCover LV liquid polish). Repeated measures ANOVA was applied for Ra and Knoop Microhardness. For the color (ΔE) three-way ANOVA was applied. In cases of statistically significant the Tukey posttest was applied (α = 0.05). Both types of polishing tested resulted in a surface smoothness below the critical value established by the studies (Ra ≥ 0.2 μm), even after immersion. The microhardness of all composite resins decreased after the challenges. The specimens immersed in HCl showed a lower microhardness (42.2 Kgf/mm2) when compared to the specimens immersed in artificial saliva (44.7 Kgf/mm2). Regarding the color change, the composites presented values compatible with clinical acceptability, with a statistically significant difference only between the control group and the other types of polishing for the Z350 XT resin (ΔE00 = 3.78). It was concluded that both mechanical and chemical polishing produced a satisfactory surface smoothness, even after immersions in artificial saliva and HCl. The microhardness of the composites was affected by the challenges and the composites tested were within clinical acceptability with regard to color change.

本研究旨在体外评估两种不同抛光技术提供的表面光滑度,以及酸挑战对三种纳米颗粒复合材料表面粗糙度(Ra)、显微硬度(Knoop)和颜色(ΔE00)变化的影响,模拟暴露在盐酸(HCl)中 1 年的情况。每种复合材料的 80 个试样被分为四组(n = 240),分别是未抛光对照组、有磨损对照组、WPC(磨损 + 使用 Cosmedent Kit 进行抛光)和 WPB(磨损 + BisCover LV 液体抛光剂)。对 Ra 和努氏显微硬度进行了重复测量方差分析。对颜色(ΔE)采用了三方方差分析。在统计意义显著的情况下,采用 Tukey 后验(α = 0.05)。所测试的两种抛光方式都导致表面光滑度低于研究确定的临界值(Ra ≥ 0.2 μm),即使在浸泡之后也是如此。所有复合树脂的显微硬度在测试后都有所下降。与浸泡在人工唾液中的试样(44.7 Kgf/mm2)相比,浸泡在盐酸中的试样显微硬度较低(42.2 Kgf/mm2)。在颜色变化方面,复合材料的颜色值符合临床接受程度,只有 Z350 XT 树脂在对照组和其他抛光类型之间存在显著差异(ΔE00 = 3.78)。结论是,即使在人工唾液和盐酸中浸泡后,机械抛光和化学抛光都能产生令人满意的表面光滑度。复合材料的显微硬度受到挑战的影响,测试的复合材料的颜色变化在临床可接受范围内。
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引用次数: 0
Analysis of a Combination Therapy Protocol for the Treatment of Oral Mucous Membrane Pemphigoid: A Retrospective Case Series Study. 治疗口腔粘膜丘疹病的联合疗法方案分析:回顾性病例系列研究。
IF 2.1 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-02-08 eCollection Date: 2024-01-01 DOI: 10.1155/2024/5524514
Simona Santonocito, Alessandro Polizzi, Marco Matarese, Rosario Caltabiano, Gaetano Isola

Mucous membrane pemphigoid (MMP) is an autoimmune-based bullous disease affecting the mucous membranes, mainly oral and ocular. One of the most common clinical manifestations is desquamative gingivitis (DG), characterized by intense symptoms and functional limitations. The dentist is among the first specialists to observe DG and, therefore, must be able to diagnose it. In this regard, the purpose of the present study was to evaluate the efficacy and safety of a clinical protocol for the topical management of patients with DG and MMP buccal lesions. Thirteen patients with clinical and histologic diagnoses of MMP-localized DG in the oral cavity were retrospectively enrolled. Each patient received topical treatment with clobetasol propionate oral gel 0.05%; nicotinamide; oral probiotic (contains Bifidobacterium lactis HN019, Kluyveromyces marxianus fragilis B0399, colostrum, and biotin); and doxycycline. Before and after 3 months of therapy, clinic records were collected for each patient. Seven patients (53.8%) had a complete response to treatment; four patients (30.8%) had a partial response to treatment; and, finally, two patients (15.4%) had no benefit from therapy. Dental management of patients presenting solely with oral manifestations of MMP may involve the use of topical corticosteroids, doxycycline, vitamin supplements, and probiotics and associating professional oral hygiene procedures.

粘膜丘疹性类风湿关节炎(MMP)是一种基于自身免疫的大疱性疾病,主要影响口腔和眼部粘膜。最常见的临床表现之一是脱屑性牙龈炎(DG),其特点是症状强烈和功能受限。牙医是最先观察到牙龈炎的专家之一,因此必须具备诊断牙龈炎的能力。因此,本研究旨在评估对 DG 和 MMP 口腔病变患者进行局部治疗的临床方案的有效性和安全性。本研究回顾性地纳入了 13 名临床和组织学诊断为口腔 MMP 定位 DG 的患者。每位患者都接受了氯倍他索丙酸酯口服凝胶 0.05%、烟酰胺、口服益生菌(含乳双歧杆菌 HN019、马克氏脆杆菌 Kluyveromyces marxianus fragilis B0399、牛初乳和生物素)和强力霉素的局部治疗。在治疗 3 个月前后,收集了每位患者的门诊记录。结果显示,7 名患者(53.8%)对治疗有完全反应;4 名患者(30.8%)对治疗有部分反应;最后,2 名患者(15.4%)没有从治疗中获益。对于仅有口腔表现的 MMP 患者,牙科治疗可包括使用局部皮质类固醇、多西环素、维生素补充剂和益生菌,以及相关的专业口腔卫生程序。
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引用次数: 0
Effectiveness of Calcium Hydroxide and Gingerols Mixture as a Novel Obturation Material for Infected Root in Primary Teeth: A Randomized Clinical Trial. 氢氧化钙和姜酚混合物作为新型牙根感染封闭材料的有效性:随机临床试验。
IF 2.1 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-02-08 eCollection Date: 2024-01-01 DOI: 10.1155/2024/5528260
Fathi A Qasem, Salwa M Awad, Rizk A Elagamy

Introduction: The tendency to use dental materials of plant origin is one of the prevailing trends in dentistry to reduce exposure to materials that could have some toxic impact in the long term.

Objective: To evaluate the efficacy of calcium hydroxide combined with gingerols (Ginge-Cal) as a novel obturation material for treating infected primary teeth and decreasing the recurrence of infection.

Materials and methods: The study was conducted on 30 lower primary molars with infected pulp for children aged 4-8 years. The sample was randomly divided into two groups depending on the tested obturation material: Ginge-Cal group and the Metapex group. The evaluation was done by different parameters clinically and radiographically at various intervals up to 12 months.

Results: Based on chi-squared and McNamara's test with a 5% significance level, the clinical results indicated that Ginge-Cal group was more effective than the Metapex group in reducing or eliminating pain (P=0.467) after 1 week, sensitivity to percussion (P=0.090) at 3 months of follow-up, purulent swelling (P=0.444) at 6 and 9 months of follow-up, fistula, and tooth mobility. The radiographic results, based on the periapical and furcation area radiolucency at 12 months of follow-up, favored Ginge-Cal group over the Metapex group (P=0.683), (P=0.456), respectively. There were no statistically significant differences in pathological root resorption and periodontal space. The differences within the Ginge-Cal group were directly influenced by the time intervals in a statistically significant manner, ranging from (P=0.004) to (P < 0.001). The success percentage was 87.5% for Ginge-Cal group and 64.3% for Metapex group.

Conclusions: Ginge-Cal can be considered a promising material for treating the infected root canal when used as an obturation material for the infected root canal. This trial is registered with NCT05181813.

导言:使用源自植物的牙科材料是牙科领域的主流趋势之一,其目的是减少接触可能长期产生毒性影响的材料:目的:评估氢氧化钙与姜酚(Ginge-Cal)作为新型封闭材料治疗感染性乳牙并减少感染复发的效果:研究对象是 30 颗牙髓感染的小学下磨牙,年龄在 4-8 岁之间。根据测试的封闭材料,样本被随机分为两组:Ginge-Cal组和Metapex组。每隔 12 个月通过临床和影像学的不同参数进行评估:根据卡方检验和麦克纳马拉检验(显著性水平为 5%),临床结果显示,Ginge-Cal 组在减轻或消除 1 周后的疼痛(P=0.467)、随访 3 个月时的叩诊敏感性(P=0.090)、随访 6 个月和 9 个月时的化脓性肿胀(P=0.444)、瘘管和牙齿活动度方面比 Metapex 组更有效。根据随访 12 个月时根尖周和毛囊区的放射线结果,Ginge-Cal 组优于 Metapex 组(P=0.683)和(P=0.456)。病理根吸收和牙周间隙的差异无统计学意义。Ginge-Cal组内的差异直接受时间间隔的影响,从(P=0.004)到(P < 0.001)均有统计学意义。Ginge-Cal组的成功率为87.5%,Metapex组为64.3%:结论:如果将 Ginge-Cal 用作感染根管的封固材料,可以认为它是治疗感染根管的一种很有前景的材料。该试验已在 NCT05181813 上注册。
{"title":"Effectiveness of Calcium Hydroxide and Gingerols Mixture as a Novel Obturation Material for Infected Root in Primary Teeth: A Randomized Clinical Trial.","authors":"Fathi A Qasem, Salwa M Awad, Rizk A Elagamy","doi":"10.1155/2024/5528260","DOIUrl":"10.1155/2024/5528260","url":null,"abstract":"<p><strong>Introduction: </strong>The tendency to use dental materials of plant origin is one of the prevailing trends in dentistry to reduce exposure to materials that could have some toxic impact in the long term.</p><p><strong>Objective: </strong>To evaluate the efficacy of calcium hydroxide combined with gingerols (Ginge-Cal) as a novel obturation material for treating infected primary teeth and decreasing the recurrence of infection.</p><p><strong>Materials and methods: </strong>The study was conducted on 30 lower primary molars with infected pulp for children aged 4-8 years. The sample was randomly divided into two groups depending on the tested obturation material: Ginge-Cal group and the Metapex group. The evaluation was done by different parameters clinically and radiographically at various intervals up to 12 months.</p><p><strong>Results: </strong>Based on chi-squared and McNamara's test with a 5% significance level, the clinical results indicated that Ginge-Cal group was more effective than the Metapex group in reducing or eliminating pain (<i>P</i>=0.467) after 1 week, sensitivity to percussion (<i>P</i>=0.090) at 3 months of follow-up, purulent swelling (<i>P</i>=0.444) at 6 and 9 months of follow-up, fistula, and tooth mobility. The radiographic results, based on the periapical and furcation area radiolucency at 12 months of follow-up, favored Ginge-Cal group over the Metapex group (<i>P</i>=0.683), (<i>P</i>=0.456), respectively. There were no statistically significant differences in pathological root resorption and periodontal space. The differences within the Ginge-Cal group were directly influenced by the time intervals in a statistically significant manner, ranging from (<i>P</i>=0.004) to (<i>P</i> < 0.001). The success percentage was 87.5% for Ginge-Cal group and 64.3% for Metapex group.</p><p><strong>Conclusions: </strong>Ginge-Cal can be considered a promising material for treating the infected root canal when used as an obturation material for the infected root canal. This trial is registered with NCT05181813.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2024 ","pages":"5528260"},"PeriodicalIF":2.1,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10869195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139740961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychometric Testing of HeLD-14 in a Colombian Geriatric Population. 在哥伦比亚老年群体中对 HeLD-14 进行心理测试。
IF 2.1 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-02-07 eCollection Date: 2024-01-01 DOI: 10.1155/2024/5570671
Ana Cristina Mafla, Mauricio Herrera-López, Carmen Gallardo-Pino, Falk Schwendicke

Introduction: The objective of this study was to test the validity and reliability of the Colombian version of the Health Literacy in Dentistry (HeLD-14) in older adults.

Materials and methods: A translation and validation study of HeLD-14 was conducted on 384 non-institutionalized older adults attending the Dental Clinic at Universidad Cooperativa from Pasto, Colombia. A cross-cultural adaptation of a multidimensional HeLD-14 was completed, and the psychometric properties of this scale were evaluated through a cross-validation method using an exploratory factor analysis (EFA) and a confirmatory factor analysis (CFA). Internal consistency was measured with Cronbach's alpha (α) and Omega's McDonald (ɷ). The statistical significance was set at P < 0.05.

Results: The EFA demonstrated that a single-factor structure with 11 items explained a cumulative 59.86% of the overall variance. The CFA confirmed that goodness of fit indices of this questionnaire had optimal adequateness (χ2S-B = 109.047; χ2S-B/(44) = 2.478, P=0.001; non-normed fit index = 0.901; comparative fit index = 0.908; root mean square error of approximation = 0.079 (90% CI (0.075, 0.083)); standardized root mean residual = 0.080). The coefficients indicated a high internal consistency for the total scale (α = 0.94; ɷ = 0.96).

Conclusion: The developed adaptation of HeLD-14 for the Colombian population, HeLD-Col, is a unidimensional, reliable, and valid instrument to assess oral health literacy in older adults in Colombia.

内容简介本研究的目的是测试哥伦比亚版牙科健康素养(HeLD-14)在老年人中的有效性和可靠性:对哥伦比亚帕斯托合作大学牙科诊所的 384 名非住院老年人进行了 HeLD-14 的翻译和验证研究。对多维 HeLD-14 进行了跨文化改编,并通过探索性因子分析 (EFA) 和确认性因子分析 (CFA) 的交叉验证方法对该量表的心理测量特性进行了评估。内部一致性采用 Cronbach's alpha (α) 和 Omega's McDonald (ɷ)进行测量。统计显著性设定为 P <0.05:EFA 表明,有 11 个项目的单因素结构累计解释了 59.86% 的总体方差。CFA证实该问卷的拟合优度指数达到最佳(χ2S-B = 109.047;χ2S-B/(44) = 2.478,P=0.001;非标准化拟合指数 = 0.901;比较拟合指数 = 0.908;均方根近似误差 = 0.079 (90% CI (0.075, 0.083));标准化均方根残差 = 0.080)。系数表明总量表具有较高的内部一致性(α = 0.94;ɷ = 0.96):结论:针对哥伦比亚人群开发的 HeLD-14 改编量表 HeLD-Col 是评估哥伦比亚老年人口腔健康素养的单维度、可靠且有效的工具。
{"title":"Psychometric Testing of HeLD-14 in a Colombian Geriatric Population.","authors":"Ana Cristina Mafla, Mauricio Herrera-López, Carmen Gallardo-Pino, Falk Schwendicke","doi":"10.1155/2024/5570671","DOIUrl":"10.1155/2024/5570671","url":null,"abstract":"<p><strong>Introduction: </strong>The objective of this study was to test the validity and reliability of the Colombian version of the Health Literacy in Dentistry (HeLD-14) in older adults.</p><p><strong>Materials and methods: </strong>A translation and validation study of HeLD-14 was conducted on 384 non-institutionalized older adults attending the Dental Clinic at Universidad Cooperativa from Pasto, Colombia. A cross-cultural adaptation of a multidimensional HeLD-14 was completed, and the psychometric properties of this scale were evaluated through a cross-validation method using an exploratory factor analysis (EFA) and a confirmatory factor analysis (CFA). Internal consistency was measured with Cronbach's alpha (<i>α</i>) and Omega's McDonald (<i>ɷ</i>). The statistical significance was set at <i>P</i> < 0.05.</p><p><strong>Results: </strong>The EFA demonstrated that a single-factor structure with 11 items explained a cumulative 59.86% of the overall variance. The CFA confirmed that goodness of fit indices of this questionnaire had optimal adequateness (<i>χ</i><sup>2</sup><sub>S-B</sub> = 109.047; <i>χ</i><sup>2</sup><sub>S-B</sub>/(44) = 2.478, <i>P</i>=0.001; non-normed fit index = 0.901; comparative fit index = 0.908; root mean square error of approximation = 0.079 (90% CI (0.075, 0.083)); standardized root mean residual = 0.080). The coefficients indicated a high internal consistency for the total scale (<i>α</i> = 0.94; <i>ɷ</i> = 0.96).</p><p><strong>Conclusion: </strong>The developed adaptation of HeLD-14 for the Colombian population, HeLD-Col, is a unidimensional, reliable, and valid instrument to assess oral health literacy in older adults in Colombia.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2024 ","pages":"5570671"},"PeriodicalIF":2.1,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10866630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139735170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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International Journal of Dentistry
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