International Journal of Dentistry最新文献

Surface modification and biomimetic approaches have been widely used to enhance bioinert substances. It is not very clear whether surface alterations and polymer coatings on titanium make it more biologically active and enhance cell adhesion. We tried to focus on the physical and biological characterization of surface-modified titanium disks. Four different surface modifications were done for the titanium disks, ranging from acid etching, sandblasting, polydopamine coating, and polydopamine-based chitosan coating, and were compared with disks without any surface modification. The disks were studied for physical characteristics like surface roughness and contact angle. Human gingival fibroblasts were used to investigate the biological effects of surface modification of titanium alloy surfaces. The wettability of chitosan-coated, acid-etched, and polydopamine-coated titanium was much better than that of the sandblasted surface, indicating that surface energy was higher for acid-etched and coated surfaces than others. The cell seeding with fibroblasts showed increased adhesion to the smoother surfaces as compared to the rougher surfaces. Polydopamine coatings on titanium disks showed the most favorable physical and biological properties compared to others and can be a good surface coating for in vivo implants.

Methods: Patients examined during postloading maintenance visits were included in this study. The presence of peri-implant mucositis, peri-implantitis and several patient- and implant-related independent variables was recorded. Statistical analysis was performed using the logistic regression analysis. The odds ratios (OR) of the potential association between each variable and the occurrence of peri-implant diseases were evaluated.

Results: Among the 114 participants with 403 implants, peri-implantitis was found in at least one implant of nine individuals (7.89%), and a total of 13 implants were affected by peri-implantitis (3.22%). The univariate regression analysis revealed a statistically significant association between arch (OR = 4.81; 95% CI = 1.27-31.36) and soft tissue thickness (OR = 4.07; 95% CI = 1.33-13.73) with the occurrence of peri-implantitis. The multivariate analysis confirmed the significant impact of soft tissue thickness (OR = 3.60; 95% CI = 1.16-12.24).

Conclusion: The occurrence of peri-implant diseases can be influenced by various factors. However, in order to accurately identify risk indicators, it is necessary to conduct long-term prospective studies.

Purpose: To analyze prosthetic complications of single screw-retained implant-supported metal-ceramic fixed prostheses (SSIMCFPs).

Materials and methods: A total of 457 medical records of patients treated with implants at the University Dental Clinic of the European University of Valencia from 2016 to 2022 were reviewed. Of the 335 SSIMCFPs evaluated, 222 were included. The following data were collected from medical records: age, sex, prosthesis location, implant diameter, type of antagonist, date of prosthesis placement, type of prosthetic complications, and the date of the occurrence of complications. Statistical analysis was estimated at the patient level with a simple binary logistic regression and at the prosthesis level, a simple logistic regression with generalized estimating equation models (p  < 0.05).

Results: A total of 222 SSIMCFPs were placed in 159 patients. The prevalence of complications was 23.3% at the patient level, equivalent to 21.6% of SSIMCFPs. A total of 48 complications were collected; screw loosening was the most frequent complication (16.2%), followed by ceramic fracture (3.1%), screw fracture (1.8%), and implant fracture (0.5%). There were no cases of abutment fracture. The mean time of the loosening of the screw was 10.5 months and ceramic fractures at 6.9 months. The factors that most influenced the occurrence of prosthetic complications were posterior position (p  < 0.001), implant diameter from 3.5 to 4.8 mm (p  < 0.01), and lower arch position (p  < 0.05).

Conclusions: The most frequent complication of SSIMCFP was loosening of the screw followed by ceramic fracture. The appearance of these complications usually occurred during the first year after SSIMCFP placement. Factors related to the occurrence of complications were mandibular posterior location and implant diameter from 3.5 to 4.8 mm.

Objectives: This study aimed to develop a gel with dentin-remineralizing properties, integrating nano-hydroxyapatite (nHA), sodium fluoride (NaF), and bioactive glass (BG).

Materials and methods: The enamel layer of 40 bovine incisors was removed. The samples were allocated into four groups of 10 each, based on varying concentrations of nHA, BG, and NaF in the gel compositions (wt%): (1) 2.5%-7.5%-0.05%, (2) 5%-5%-0.05%, (3) 7.5%-2.5%-0.05%, and (4) a control group with a base gel lacking remineralizing agents. After 8 hr of demineralization, the dentin surface microhardness was measured at depths of 30, 60, and 140 µm. After a 20-day pH cycling, the percentage of surface microhardness recovery (SMHR%) was measured and compared among the groups using the ANOVA and Tukey HSD post hoc tests (α = 0.05). Scanning electron microscopy analysis evaluated each specimen's superficial morphology.

Results: At all depths, the SMHR% of the Group 2 and Group 3 was significantly higher than the control group (p  < 0.05). The SMHR% Group 1 (67.39% ± 29.34%) was significantly higher than the control group (-21.24% ± 51.72%) only at the depth of 30 μm (p = 0.047). Group 3 had higher SMHR% than Group 2 at all depths; however, the difference was not statistically significant. Moreover, the SMHR% of Group 3 was significantly higher than that of Group 1 at depths of 30 μm (187. 94% ± 68.95% vs. 67.39% ± 29.34%; p = 0.005) and 60 μm (179.55% ± 75.96% vs. 64.34% ± 41.96%; p = 0.043). Surface deposition and tubule occlusion were observed in the Groups 2 and 3 samples, which was more prominent in the latter.

Conclusions: Combining 7.5% nHA, 2.5% BG, and 0.05% NaF could potentially remineralize primary carious lesions.

Aim: The current study introduces a novel, algorithm-based software developed to objectively evaluate dental cavity preparations. The software aims to provide an alternative or complement to traditional, subjective assessment methods used in operative dentistry education.

Materials and methods: The software was tested on cavity preparations carried out by 70 participants on artificial molar teeth. These cavities were also independently assessed by an experienced academic panel. The software, using 3D imaging, calculated cavity dimensions and assigned an error score based on deviation from ideal measurements. Statistical analyses included sensitivity, specificity, positive predictive value, negative predictive value, Cohen's kappa, the intraclass correlation coefficient (ICC3k), Spearman's rho, Kendall's tau correlation coefficients, and a confusion matrix.

Result: The software demonstrated a high degree of accuracy and agreement with the panel assessments. The average software and panel scores were 64.1 and 60.91, respectively. Sensitivity (0.98) was high, specificity (0.55) was moderate, and the ICC3k value (0.857) indicated a strong agreement between the software and the panel. Further, Spearman's rho (0.73) and Kendall's tau (0.56) suggested a strong correlation between the two grading methods.

Conclusion: The results support the algorithm-based software as a valid and reliable tool for dental cavity preparation assessments. The software's potential use in dental education is promising, though future research is necessary to validate and optimize this technology for wider application.

Introduction: The utilization of ceramics in the field of dentistry has seen a significant rise owing to their esthetic appeal and excellent functional properties. The use of ceramics in the field of dentistry has witnessed a notable surge, driven by their appealing esthetics and exceptional functional attributes. Zirconia, distinguished by its exceptional mechanical strength, plays a pivotal role in the fabrication of posterior crowns and bridges. Among zirconia variants, monolithic zirconia stands out, where the entire restoration is crafted from zirconia material. In parallel, feldspathic porcelain, chosen for its remarkable resemblance to natural tooth enamel, represents another significant ceramic type. This study aims to evaluate the shear bond strength (SBS) between two types of monolithic zirconia with two types of feldspathic porcelain.

Methods and materials: Forty-four monolithic zirconia veneered discs with feldspathic porcelain were subjected to SBS testing. The dimensions of the discs were 7 mm in diameter and 5 mm in height (3 mm of zirconia and 2 mm of porcelain). Subsequently, the specimens were subjected to a universal testing machine at a speed of 0.5 mm/min until failure occurred. The type of failure was examined using scanning electron microscopy. One-way analysis of variance (ANOVA), two-way ANOVA, Fisher's test, and multiple Tukey comparisons were used as statistical analyses.

Results: The highest SBS was achieved by the high-translucency monolithic zirconia with enamel porcelain group (18.81 ± 3.18 MPa) and the high-translucency monolithic zirconia with dentin porcelain group (17.89 ± 2.75 MPa), followed by the low-translucency monolithic zirconia with dentin porcelain group (15.04 ± 2.24 MPa) and the low-translucency monolithic zirconia with enamel porcelain group (14.33 ± 2.00 MPa), respectively. Additionally, the most common type of failure pattern observed was mixed, followed by adhesive failure.

Conclusion: The translucency of the porcelain did not significantly affect SBS, while the type of monolithic zirconia used had a significant impact. Furthermore, there was no discernible relationship between the four groups in terms of the distribution of failure patterns.

Background: Biomarkers can be measured in various biological samples. Urine is among the most useful biofluids for routine testing, and several experimental and clinical studies support its role as a tool for the diagnosis and prevention of various diseases. The present systematic review aimed to examine periodontitis-specific urine biomarkers that could have a diagnostic relevance and to provide a qualitative assessment of the current literature.

Materials and methods: Relevant studies identified from PubMed, Embase, Cochrane Library, and Scopus databases were examined to answer the following PECO question: "Could the concentration of specific metabolites in the urine be related to periodontal health and what is their diagnostic accuracy?". Quality of included studies was rated using ROBINS-I tool. Meta-analysis was conducted on available quantitative data.

Results: After the screening of 768 titles, five studies were included in qualitative synthesis. The studies included referred to the evaluation of 8-hydroxy-2'-deoxyguanosine (8-OHdG) and neopterin. Meta-analysis was conducted for neopterin concentration on data available in four studies involving 129 participants. Higher concentrations of neopterin were found in periodontitis-affected patients compared to controls and patients treated for periodontitis.

Conclusions: The literature appears controversial in attributing a role to neopterin and 8-OHdG as periodontal biomarkers, highlighting the need for further clinical studies on this topic. While some studies report variations in 8-OHdG and neopterin levels in periodontally affected patients versus either controls or periodontally treated patients, the level of evidence appears still limited to draw firm conclusions (PROSPERO CRD42020222681).

Objective: To examine the association between molar-incisor hypomineralization (MIH) and the prevalence of thinness among Mexican schoolchildren in communities with different fluoride levels in the drinking water.

Methods: A cross-sectional study on Mexican children (n = 488) selected from two communities presenting different concentrations of fluoride in the drinking water (1.0-1.40 ppm/F). The World Health Organization (WHO) growth standards were used to calculate BMI-for-age z-scores, with BMI z-score cutoff points of <-2.0, >+1.0, >+2.0 recommended for defining thinness, being overweight, and obesity. The presence and severity of MIH were evaluated using the European Academy of Paediatric Dentistry (EAPD) criteria. Multiple logistic regression analyses were used to assess the association, adjusting for confounders.

Results: The proportion of children presenting thinness, being overweight, and obesity was 8.2%, 23.6%, and 28.7%, respectively, while 21.5% of the schoolchildren had MIH, classified, by severity, as 9.6% mild, 6.4% moderate, and 5.5% severe. Of those schoolchildren presenting thinness, 16.2% had MIH, and only 6.0% did not (p  < 0.001). Finally, schoolchildren presenting thinness were more likely to present MIH (OR = 2.76 (CI 95% 1.33-5.73); p=0.006) than children with a normal BMI.

Conclusion: The present study found a relationship between thinness and the presence of MIH in schoolchildren, indicating the need for strategies and interventions aimed at preventing and controlling micronutrient deficiencies in the child population.

Objectives: Rotary single-file endodontic systems are commonly used for root canal treatment. However, very few studies have evaluated the apical extrusion of debris generated by these systems during canal preparation at normal body temperature in laboratory conditions. The aim of this study was to evaluate the amount of apically extruded debris caused by seven different single-file endodontic instrumentation systems at body temperature in mandibular molar teeth with curved root canals.

Methods: One hundred forty mandibular first permanent molars were randomly divided into seven groups (n = 20) to be prepared by one of the following systems at 35°C: Reciproc Blue (REC Blue), WaveOne Gold (WOG), One Reci (OR), Neoniti, HyFlex EDM (HEDM), One Curve (OC), or XP Shaper (XPS). Debris was collected into preweighted Eppendorf tubes. The weight of the extruded debris was recorded by subtracting the weight of the tooth-free apparatus from the post-procedure weight. Data were analyzed by one-way ANOVA and Tukey's tests (p  < 5%).

Results: REC Blue, WOG, and OR groups extruded significantly more debris from the apex than XPS, OC, and Neoniti groups (p  < 0.05). No significant difference was observed among the XPS, OC, Neoniti, and HEDM groups (p  > 0.05).

Conclusion: All the instruments were associated with debris extrusion. However, REC Blue, WOG, and OR extrude significantly more debris than other instruments. The amount of debris with different files was REC Blue > OR > WOG > HEDM > OC > Neoniti > XPS. XPS, Neoniti, and OC caused significantly less extrusion of debris than REC Blue, WOG, and OR.

Purpose: Community-based dental education (CBDE) diverges from traditional dental school training methods by integrating dental students into primary care community settings. This immersive approach enables students to refine their clinical and hands-on skills while serving the oral health needs of underserved populations. This study aimed to identify ways in which Australian dental schools are currently implementing CBDE and compared to current evidence.

Materials and methods: This study utilized a 24-item, self-completion survey, adapted from existing questionnaires, which was sent to the CBDE coordinators in the nine eligible dental programs in Australia between mid-January 2023 and mid-April 2023. The survey consisted of multiple-choice, binary, and open-ended questions, including information on the level of student involvement, types of external clinics used, length of rotations, student supervision and assessment, pre-rotation preparation, and post-rotation evaluation, as well as challenges faced in implementing programs.

Results: Six of the nine invited coordinators responded, resulting in a 66.7% response rate. All participants confirmed that their schools had a community-based teaching program. All six respondents reported that participation in external clinics is required for graduation. Implementation of CBDE appears to be influenced by (1) level of student involvement, (2) the types of clinics utilised, (3) allocation and length of rotation, (4) student supervision and assessment, (5) pre-rotation preparation, and (6) post-rotation evaluation. Six (n = 6) institutions reported requiring a post-rotation reflection from students and all respondents reported seeking feedback from clinical supervisors at external sites. Emerging themes from open-ended questions highlight challenges in coordinating external rosters, securing funding, supervising students at external sites, and ensuring diverse types of student exposure during external rotations.

Conclusion: This study provided insights into the implementation of CBDE in Australian dental schools. Results outlined in this research offer valuable insights for dental schools aiming to enhance their programs and improve student learning outcomes.