Seaweed-derived dietary fibre sodium alginate (SA) has been shown to present with health benefits in food-derived disease models. To determine whether SA improves the disease rather than merely suppressing its progression, we assessed its effects using farnesoid X receptor (FXR)-deficient mice to provide a model of advanced hyperlipidaemia. Fxr-null mice were fed with a 5% SA-supplemented diet for nine weeks and showed significant decreases in the levels of liver triglycerides (p < 0.05), total cholesterol (p < 0.05), serum low-density lipoprotein-cholesterol (p < 0.001). The expression levels of fatty acid-synthesizing genes (Fas and Scd1) and cholesterol-metabolizing genes (Hmgcr, Hmgcs, and Abca1), were significantly reduced. Furthermore, the SA supplementation has altered the gut microbiota and significantly increased the abundance of the genus Oscillospira (p < 0.001) and Parabacteroides (p < 0.01). These results suggest that SA improves lipid disruption and influences the composition of the gut microbiota in the Fxr-null mice.
{"title":"Sodium alginate improves lipid disruption and alters the composition of the gut microbiota in farnesoid X receptor-null mice.","authors":"Masaaki Miyata, Kouhei Maeno, Reina Takagi, Yoshimasa Sugiura","doi":"10.1080/09637486.2025.2471106","DOIUrl":"10.1080/09637486.2025.2471106","url":null,"abstract":"<p><p>Seaweed-derived dietary fibre sodium alginate (SA) has been shown to present with health benefits in food-derived disease models. To determine whether SA improves the disease rather than merely suppressing its progression, we assessed its effects using farnesoid X receptor (FXR)-deficient mice to provide a model of advanced hyperlipidaemia. Fxr-null mice were fed with a 5% SA-supplemented diet for nine weeks and showed significant decreases in the levels of liver triglycerides (<i>p</i> < 0.05), total cholesterol (<i>p</i> < 0.05), serum low-density lipoprotein-cholesterol (<i>p</i> < 0.001). The expression levels of fatty acid-synthesizing genes (<i>Fas</i> and <i>Scd1</i>) and cholesterol-metabolizing genes (<i>Hmgcr, Hmgcs</i>, and <i>Abca1</i>), were significantly reduced. Furthermore, the SA supplementation has altered the gut microbiota and significantly increased the abundance of the genus <i>Oscillospira</i> (<i>p</i> < 0.001) and <i>Parabacteroides</i> (<i>p</i> < 0.01). These results suggest that SA improves lipid disruption and influences the composition of the gut microbiota in the Fxr-null mice.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"304-314"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01Epub Date: 2025-02-26DOI: 10.1080/09637486.2025.2466111
Roghayeh Molani-Gol, Maryam Rafraf
This systematic review aimed to summarise the current knowledge regarding the effects of the Mediterranean diet (MD) on the secondary prevention of cardiovascular diseases (CVDs). A systematic search was done on Web of Sciences, PubMed, Scopus, and Google Scholar databases until January 2025. The majority of the included studies (15 of 16 RCTs) supported the role of MD following in the secondary prevention of CVDs. According to the RCT results, the patients in the MD group had lower cardiovascular deaths, non-fatal myocardial infarction, and other events. They also had healthier lipid profiles and blood fatty acids, higher flow-mediated dilation and endothelial progenitor cell levels, and lower endothelial progenitor cells compared to a low-fat diet. However, both MD and control (low-fat diet) groups promoted similar decreases in blood pressure and body mass index. The findings of this review suggested that adherence to the MD could be beneficial in the secondary prevention of CVD.
本系统综述旨在总结目前有关地中海饮食(Mediterranean diet,MD)对心血管疾病(CVDs)二级预防效果的知识。截至 2025 年 1 月,我们在 Web of Sciences、PubMed、Scopus 和 Google Scholar 数据库中进行了系统检索。纳入的大多数研究(16 项研究性试验中的 15 项)都支持采用地中海饮食对心血管疾病进行二级预防。根据临床试验结果,MD 组患者的心血管死亡、非致命性心肌梗死和其他事件发生率较低。与低脂饮食相比,他们的血脂状况和血液脂肪酸也更健康,血流介导的扩张和内皮祖细胞水平更高,而内皮祖细胞水平更低。不过,MD 组和对照组(低脂饮食)在降低血压和体重指数方面的效果相似。这项研究结果表明,坚持 MD 有助于心血管疾病的二级预防。
{"title":"Effects of the Mediterranean diet on the secondary prevention of cardiovascular diseases: a systematic review of randomised controlled trials.","authors":"Roghayeh Molani-Gol, Maryam Rafraf","doi":"10.1080/09637486.2025.2466111","DOIUrl":"10.1080/09637486.2025.2466111","url":null,"abstract":"<p><p>This systematic review aimed to summarise the current knowledge regarding the effects of the Mediterranean diet (MD) on the secondary prevention of cardiovascular diseases (CVDs). A systematic search was done on Web of Sciences, PubMed, Scopus, and Google Scholar databases until January 2025. The majority of the included studies (15 of 16 RCTs) supported the role of MD following in the secondary prevention of CVDs. According to the RCT results, the patients in the MD group had lower cardiovascular deaths, non-fatal myocardial infarction, and other events. They also had healthier lipid profiles and blood fatty acids, higher flow-mediated dilation and endothelial progenitor cell levels, and lower endothelial progenitor cells compared to a low-fat diet. However, both MD and control (low-fat diet) groups promoted similar decreases in blood pressure and body mass index. The findings of this review suggested that adherence to the MD could be beneficial in the secondary prevention of CVD.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"226-238"},"PeriodicalIF":3.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01Epub Date: 2025-02-13DOI: 10.1080/09637486.2025.2464665
Xinying Suo, Oscar Moreno-Araiza, Margherita Dall'Asta, Gianluca Giuberti, Alessio Marchesani, Elena Vittadini
Pulse pasta has, in recent years, gained the interest of consumers and food manufacturers and a deeper understanding of the the effects of flour types and pasta processing on its physical and nutritional characteristics has become a priority. This work investigates the effects of red lentil flour type (raw or pre-cooked), pasta extrusion pressure (i.e. 80 and 125 bars), and drying temperature (i.e.,50 and 80 °C) on pasta quality and in vitro nutritional digestibility. A significant reduction in cooking loss was found in pasta extruded at high pressure and dried at high temperature (80 °C), while all pasta had acceptable cooking quality in terms of length, thickness and weight gains. More slowly digestible starch was found in pasta dried at high temperatures, while less rapidly digestible and more resistant starch was present in pasta extruded at high pressure. In vitro starch digestibility can be effectively reduced by applying proper processing conditions (i.e. high extrusion pressure) which could be vital for designing a 100% legume pasta with modulated glycemic response.
{"title":"Red lentil pasta quality and <i>in vitro</i> digestibility modulation by means of processing conditions.","authors":"Xinying Suo, Oscar Moreno-Araiza, Margherita Dall'Asta, Gianluca Giuberti, Alessio Marchesani, Elena Vittadini","doi":"10.1080/09637486.2025.2464665","DOIUrl":"10.1080/09637486.2025.2464665","url":null,"abstract":"<p><p>Pulse pasta has, in recent years, gained the interest of consumers and food manufacturers and a deeper understanding of the the effects of flour types and pasta processing on its physical and nutritional characteristics has become a priority. This work investigates the effects of red lentil flour type (raw or pre-cooked), pasta extrusion pressure (i.e. 80 and 125 bars), and drying temperature (i.e.,50 and 80 °C) on pasta quality and <i>in vitro</i> nutritional digestibility. A significant reduction in cooking loss was found in pasta extruded at high pressure and dried at high temperature (80 °C), while all pasta had acceptable cooking quality in terms of length, thickness and weight gains. More slowly digestible starch was found in pasta dried at high temperatures, while less rapidly digestible and more resistant starch was present in pasta extruded at high pressure. <i>In vitro</i> starch digestibility can be effectively reduced by applying proper processing conditions (i.e. high extrusion pressure) which could be vital for designing a 100% legume pasta with modulated glycemic response.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"265-276"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-01Epub Date: 2025-02-19DOI: 10.1080/09637486.2025.2465763
Sofyan Maghaydah, Mohammad Alrosan, Muhammad H Alu'datt, Ammar A Razzak Mahmood, Sana Gammoh, Khalid Bani-Melhem, Farah R Al Qudsi, Thuan-Chew Tan, Ali Madi Almajwal, Ali Rashed Alshammari
Lentil proteins (LPs) may encounter challenges in their food industry applications due to certain limitations in their functional properties. This study focused on enhancing the quality of LPs through physical modifications and investigating the effects of a 24-hr fermentation process with Lactiplantibacillus plantarum. The protein structures of LPs were analysed using several techniques, including ultraviolet spectra, fluorescence spectra, and FT-IR spectra, respectively, resulting in the protein structure of LPs substantial modifications (p < 0.05) during the fermentation procedure. protein surface properties of fermented LPs, including surface charge and surface hydrophobicity, changed significantly (p < 0.05) from -23.03 to -32.70 mV and 860.30 to 600.6 a.u., respectively. Using Lactobacillus by fermentation processes can offer several benefits, particularly in enhancing the digestibility, protein structure, and nutritional values of LPs.
{"title":"Improving the structure of lentil proteins during fermentation and their association with nutritional values and solubility.","authors":"Sofyan Maghaydah, Mohammad Alrosan, Muhammad H Alu'datt, Ammar A Razzak Mahmood, Sana Gammoh, Khalid Bani-Melhem, Farah R Al Qudsi, Thuan-Chew Tan, Ali Madi Almajwal, Ali Rashed Alshammari","doi":"10.1080/09637486.2025.2465763","DOIUrl":"10.1080/09637486.2025.2465763","url":null,"abstract":"<p><p>Lentil proteins (LPs) may encounter challenges in their food industry applications due to certain limitations in their functional properties. This study focused on enhancing the quality of LPs through physical modifications and investigating the effects of a 24-hr fermentation process with <i>Lactiplantibacillus plantarum</i>. The protein structures of LPs were analysed using several techniques, including ultraviolet spectra, fluorescence spectra, and FT-IR spectra, respectively, resulting in the protein structure of LPs substantial modifications (<i>p <</i> 0.05) during the fermentation procedure. protein surface properties of fermented LPs, including surface charge and surface hydrophobicity, changed significantly (<i>p <</i> 0.05) from -23.03 to -32.70 mV and 860.30 to 600.6 a.u., respectively. Using <i>Lactobacillus</i> by fermentation processes can offer several benefits, particularly in enhancing the digestibility, protein structure, and nutritional values of LPs.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"277-289"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Our study examined the relationship between diet quality and the prevalence of metabolic syndrome (MetS) among 1779 U.S. cancer survivors using data from the National Health and Nutrition Examination Survey (NHANES, 2005-2016). Diet quality was assessed using the Healthy Eating Index 2015 (HEI-2015). Higher HEI-2015 scores were linked to significantly lower MetS prevalence (OR: 0.51, 95% CI: 0.32-0.80). Specifically, a higher intake of seafood and plant proteins, and fatty acids, coupled with a reduced intake of added sugars, was associated with decreased odds of MetS prevalence (OR: 0.93; 95% CI, 0.86-0.99) in cancer survivors. Additionally, a better diet quality was linked to lower prevalence of high waist circumference, elevated triglycerides, reduced high-density lipoprotein (HDL) cholesterol and high fasting glucose levels (OR, 0.44; 95% CI, 0.27-0.72). These results suggest that adopting healthy dietary habits may prevent MetS in cancer survivors.
{"title":"Association between Healthy Eating Index 2015 and metabolic syndrome among US cancer survivors: evidence from NHANES 2005-2016.","authors":"Jiazhen Yao, Xiaohong Chen, Yirong Xin, Fang Meng, Xiaoyan Zhong, Hanzhong Cao, Junlan Qiu, Xiaochen Shu","doi":"10.1080/09637486.2025.2461144","DOIUrl":"10.1080/09637486.2025.2461144","url":null,"abstract":"<p><p>Our study examined the relationship between diet quality and the prevalence of metabolic syndrome (MetS) among 1779 U.S. cancer survivors using data from the National Health and Nutrition Examination Survey (NHANES, 2005-2016). Diet quality was assessed using the Healthy Eating Index 2015 (HEI-2015). Higher HEI-2015 scores were linked to significantly lower MetS prevalence (OR: 0.51, 95% CI: 0.32-0.80). Specifically, a higher intake of seafood and plant proteins, and fatty acids, coupled with a reduced intake of added sugars, was associated with decreased odds of MetS prevalence (OR: 0.93; 95% CI, 0.86-0.99) in cancer survivors. Additionally, a better diet quality was linked to lower prevalence of high waist circumference, elevated triglycerides, reduced high-density lipoprotein (HDL) cholesterol and high fasting glucose levels (OR, 0.44; 95% CI, 0.27-0.72). These results suggest that adopting healthy dietary habits may prevent MetS in cancer survivors.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"315-325"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01Epub Date: 2024-12-09DOI: 10.1080/09637486.2024.2437468
Patrizia Calella, Mirella Di Dio, Concetta Paola Pelullo, Gabriella Di Giuseppe, Vincenza Sansone, Fabrizio Liguori, Valeria Di Onofrio, Giuliana Valerio, Giorgio Liguori, Francesca Gallè
This cross-sectional study was aimed to investigate knowledge, attitudes, and practices regarding dietary supplements (DS) and nutraceuticals among athletes, gym practitioners, and individuals who did not exercise regularly. A total of 372 participants, aged 18-65, completed a questionnaire covering demographics, supplement usage, and three validated tools: the Knowledge about Dietary Supplements (KaDS), Supplements Knowledge Score (SKS), and Knowledge, Attitude, and Practice towards Nutraceuticals (KAPN). Significant differences were found in the use of vitaminised water, protein powder, glucosamines, beetroot juice, creatine, omega-3, and pre-workout supplements among the groups, with gym practitioners reporting the highest usage. Athletes scored the highest in knowledge of DS effects on health, while both athletes and gym practitioners scored higher than non-exercisers in knowledge related to sports supplements. However, all groups showed inadequate knowledge of nutraceuticals, and moderately positive attitudes towards these products. Older participants performed better in knowledge questionnaires. These findings suggest that gym practitioners, inactive and young people could benefit most from educational interventions regarding dietary supplementation.
{"title":"Are knowledge, attitudes and practices about dietary supplements and nutraceuticals related with exercise practice and setting? A cross-sectional study among Italian adults.","authors":"Patrizia Calella, Mirella Di Dio, Concetta Paola Pelullo, Gabriella Di Giuseppe, Vincenza Sansone, Fabrizio Liguori, Valeria Di Onofrio, Giuliana Valerio, Giorgio Liguori, Francesca Gallè","doi":"10.1080/09637486.2024.2437468","DOIUrl":"10.1080/09637486.2024.2437468","url":null,"abstract":"<p><p>This cross-sectional study was aimed to investigate knowledge, attitudes, and practices regarding dietary supplements (DS) and nutraceuticals among athletes, gym practitioners, and individuals who did not exercise regularly. A total of 372 participants, aged 18-65, completed a questionnaire covering demographics, supplement usage, and three validated tools: the Knowledge about Dietary Supplements (KaDS), Supplements Knowledge Score (SKS), and Knowledge, Attitude, and Practice towards Nutraceuticals (KAPN). Significant differences were found in the use of vitaminised water, protein powder, glucosamines, beetroot juice, creatine, omega-3, and pre-workout supplements among the groups, with gym practitioners reporting the highest usage. Athletes scored the highest in knowledge of DS effects on health, while both athletes and gym practitioners scored higher than non-exercisers in knowledge related to sports supplements. However, all groups showed inadequate knowledge of nutraceuticals, and moderately positive attitudes towards these products. Older participants performed better in knowledge questionnaires. These findings suggest that gym practitioners, inactive and young people could benefit most from educational interventions regarding dietary supplementation.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"194-202"},"PeriodicalIF":3.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01Epub Date: 2024-12-19DOI: 10.1080/09637486.2024.2437472
Hazem Golshany, Shahinaz Ahmed Helmy, Nashwa Fathy Sayed Morsy, Aya Kamal, Qun Yu, Liuping Fan
This comprehensive review examines the impact of dietary patterns on gut microbiome composition and diversity from infancy to old age, linking these changes to age-related health outcomes. It investigates how the gut microbiome develops and changes across life stages, focusing on the influence of dietary factors. The review explores how early-life feeding practices, including breastfeeding and formula feeding, shape the infant gut microbiota and have lasting effects. In elderly individuals, alterations in the gut microbiome are associated with increased susceptibility to infections, chronic inflammation, metabolic disorders and cognitive decline. The critical role of diet in modulating the gut microbiome throughout life is emphasised, particularly the potential benefits of probiotics and fortified foods in promoting healthy ageing. By elucidating the mechanisms connecting food systems to gut health, this review provides insights into interventions that could enhance gut microbiome resilience and improve health outcomes across the lifespan.
{"title":"The gut microbiome across the lifespan: how diet modulates our microbial ecosystem from infancy to the elderly.","authors":"Hazem Golshany, Shahinaz Ahmed Helmy, Nashwa Fathy Sayed Morsy, Aya Kamal, Qun Yu, Liuping Fan","doi":"10.1080/09637486.2024.2437472","DOIUrl":"10.1080/09637486.2024.2437472","url":null,"abstract":"<p><p>This comprehensive review examines the impact of dietary patterns on gut microbiome composition and diversity from infancy to old age, linking these changes to age-related health outcomes. It investigates how the gut microbiome develops and changes across life stages, focusing on the influence of dietary factors. The review explores how early-life feeding practices, including breastfeeding and formula feeding, shape the infant gut microbiota and have lasting effects. In elderly individuals, alterations in the gut microbiome are associated with increased susceptibility to infections, chronic inflammation, metabolic disorders and cognitive decline. The critical role of diet in modulating the gut microbiome throughout life is emphasised, particularly the potential benefits of probiotics and fortified foods in promoting healthy ageing. By elucidating the mechanisms connecting food systems to gut health, this review provides insights into interventions that could enhance gut microbiome resilience and improve health outcomes across the lifespan.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"95-121"},"PeriodicalIF":3.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142864223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01Epub Date: 2025-01-12DOI: 10.1080/09637486.2024.2449037
Sepideh Soltani, Farzaneh Asoudeh, Maryam Motallaei, Roya Kolahdouz-Mohammadi, Scott C Forbes, Shima Abdollahi
This meta-analysis aims to compile all randomised controlled trials (RCTs) that examined the effects of grapes or grape products on adult anthropometric measures and serum adipokines. We searched PubMed, Scopus, Google scholar, Web of Science and CENTRAL databases published before January 2022. Random-effects model was used to combine mean differences between intervention and placebo groups. A minimal reduction was revealed for BMI following consumption of grapes/grape products [weighted mean difference (WMD): -0.14 kg]; however, no significant effects were observed on body weight, except for trials conducting in female (n = 3 studies; WMD: -0.68 kg), and those enrolled patients with metabolic syndrome (n = 3 studies; WMD: -0.62 kg). No significant effect was found for waist circumference, body fat, waist to hip ratio, serum level of leptin and adiponectin. Our findings showed that grapes or grape products have no significant anti-obesity effects on body weight, anthropometric measures, or adipokines. However, BMI showed a trivial decrease, which should not be considered given the low quality of the studies.
本荟萃分析旨在汇编所有研究葡萄或葡萄制品对成人人体测量指标和血清脂肪因子影响的随机对照试验(RCT)。我们检索了 2022 年 1 月之前发表的 PubMed、Scopus、Google scholar、Web of Science 和 CENTRAL 数据库。采用随机效应模型合并干预组和安慰剂组之间的平均差异。结果表明,食用葡萄/葡萄制品后,体重指数(BMI)的降低幅度很小[加权平均差(WMD):-0.14 千克];然而,除了针对女性(3 项研究;WMD:-0.68 千克)和代谢综合征患者(3 项研究;WMD:-0.62 千克)的试验外,未观察到对体重的显著影响。腰围、体脂、腰臀比、血清瘦素和脂肪连通素水平均无明显影响。我们的研究结果表明,葡萄或葡萄制品对体重、人体测量指标或脂肪因子没有明显的抗肥胖作用。不过,体重指数(BMI)的下降幅度微不足道,鉴于研究质量不高,不应将其视为影响因素。
{"title":"Whole grapes or grape products on body weight, anthropometrics, and adipokines: systematic review and meta-analysis of randomized controlled trials.","authors":"Sepideh Soltani, Farzaneh Asoudeh, Maryam Motallaei, Roya Kolahdouz-Mohammadi, Scott C Forbes, Shima Abdollahi","doi":"10.1080/09637486.2024.2449037","DOIUrl":"10.1080/09637486.2024.2449037","url":null,"abstract":"<p><p>This meta-analysis aims to compile all randomised controlled trials (RCTs) that examined the effects of grapes or grape products on adult anthropometric measures and serum adipokines. We searched PubMed, Scopus, Google scholar, Web of Science and CENTRAL databases published before January 2022. Random-effects model was used to combine mean differences between intervention and placebo groups. A minimal reduction was revealed for BMI following consumption of grapes/grape products [weighted mean difference (WMD): -0.14 kg]; however, no significant effects were observed on body weight, except for trials conducting in female (<i>n</i> = 3 studies; WMD: -0.68 kg), and those enrolled patients with metabolic syndrome (<i>n</i> = 3 studies; WMD: -0.62 kg). No significant effect was found for waist circumference, body fat, waist to hip ratio, serum level of leptin and adiponectin. Our findings showed that grapes or grape products have no significant anti-obesity effects on body weight, anthropometric measures, or adipokines. However, BMI showed a trivial decrease, which should not be considered given the low quality of the studies.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"122-133"},"PeriodicalIF":3.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01Epub Date: 2025-03-10DOI: 10.1080/09637486.2025.2475332
Giuseppe Grosso
{"title":"Anthocyanins for vascular health: plausible role of gut microbiota.","authors":"Giuseppe Grosso","doi":"10.1080/09637486.2025.2475332","DOIUrl":"10.1080/09637486.2025.2475332","url":null,"abstract":"","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"93-94"},"PeriodicalIF":3.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-01Epub Date: 2025-02-03DOI: 10.1080/09637486.2025.2461142
Thaís Costa de Almeida, Yasmin Neves Vieira Sabino, Poliana Guiomar de Almeida Brasiel, Beatriz Macedo de Oliveira Rocha, Gabriela de Cássia Ávila Alpino, Vinícius Novaes Rocha, Vanessa Cordeiro Dias, Cláudio Galuppo Diniz, Aline Dias Paiva, Vânia Lúcia da Silva, Julliane Dutra Medeiros, Sheila Cristina Potente Dutra Luquetti, Alessandra Barbosa Ferreira Machado
Environmental factors can play fundamental role in health in childhood and adulthood during critical developmental periods like lactation. The maternal intake of probiotics like kefir during lactation could benefit newborns' intestinal health. This study aimed to evaluate the effects of maternal kefir intake during lactation on bacterial breast milk composition and the gut microbiota of offspring Wistar male rats at weaning. Lactating Wistar rats and their pups were divided into four groups based on litter size and maternal kefir intake. Sequencing of the 16S rRNA gene in breast milk revealed the predominance of the Proteobacteria, Firmicutes, and Actinobacteriota phyla. Offspring gut microbiota exhibited clustering tendencies in kefir groups with varying genus abundance. Additionally, maternal kefir intake led to increased levels of butyrate acid in offspring faeces (> +30%, p > 0.05). These findings show that the lactation period could be a window of opportunity to program intestinal health through microbiota modulation.
{"title":"Maternal kefir intake during lactation impacts the breast milk and gut microbiota of the Wistar rat's offspring.","authors":"Thaís Costa de Almeida, Yasmin Neves Vieira Sabino, Poliana Guiomar de Almeida Brasiel, Beatriz Macedo de Oliveira Rocha, Gabriela de Cássia Ávila Alpino, Vinícius Novaes Rocha, Vanessa Cordeiro Dias, Cláudio Galuppo Diniz, Aline Dias Paiva, Vânia Lúcia da Silva, Julliane Dutra Medeiros, Sheila Cristina Potente Dutra Luquetti, Alessandra Barbosa Ferreira Machado","doi":"10.1080/09637486.2025.2461142","DOIUrl":"10.1080/09637486.2025.2461142","url":null,"abstract":"<p><p>Environmental factors can play fundamental role in health in childhood and adulthood during critical developmental periods like lactation. The maternal intake of probiotics like kefir during lactation could benefit newborns' intestinal health. This study aimed to evaluate the effects of maternal kefir intake during lactation on bacterial breast milk composition and the gut microbiota of offspring Wistar male rats at weaning. Lactating Wistar rats and their pups were divided into four groups based on litter size and maternal kefir intake. Sequencing of the 16S rRNA gene in breast milk revealed the predominance of the Proteobacteria, Firmicutes, and Actinobacteriota phyla. Offspring gut microbiota exhibited clustering tendencies in kefir groups with varying genus abundance. Additionally, maternal kefir intake led to increased levels of butyrate acid in offspring faeces (> +30%, <i>p</i> > 0.05). These findings show that the lactation period could be a window of opportunity to program intestinal health through microbiota modulation.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"179-193"},"PeriodicalIF":3.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}