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Sodium alginate improves lipid disruption and alters the composition of the gut microbiota in farnesoid X receptor-null mice. 海藻酸钠改善脂质破坏,并改变法氏体X受体缺失小鼠肠道微生物群的组成。
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-05-01 Epub Date: 2025-03-02 DOI: 10.1080/09637486.2025.2471106
Masaaki Miyata, Kouhei Maeno, Reina Takagi, Yoshimasa Sugiura

Seaweed-derived dietary fibre sodium alginate (SA) has been shown to present with health benefits in food-derived disease models. To determine whether SA improves the disease rather than merely suppressing its progression, we assessed its effects using farnesoid X receptor (FXR)-deficient mice to provide a model of advanced hyperlipidaemia. Fxr-null mice were fed with a 5% SA-supplemented diet for nine weeks and showed significant decreases in the levels of liver triglycerides (p < 0.05), total cholesterol (p < 0.05), serum low-density lipoprotein-cholesterol (p < 0.001). The expression levels of fatty acid-synthesizing genes (Fas and Scd1) and cholesterol-metabolizing genes (Hmgcr, Hmgcs, and Abca1), were significantly reduced. Furthermore, the SA supplementation has altered the gut microbiota and significantly increased the abundance of the genus Oscillospira (p < 0.001) and Parabacteroides (p < 0.01). These results suggest that SA improves lipid disruption and influences the composition of the gut microbiota in the Fxr-null mice.

海藻来源的膳食纤维海藻酸钠(SA)在食源性疾病模型中已被证明具有健康益处。为了确定SA是否能改善疾病,而不仅仅是抑制其进展,我们使用法脂类X受体(FXR)缺陷小鼠来评估其作用,以提供晚期高脂血症模型。fxr缺失小鼠在添加5% sa的饲料中喂养9周,肝脏甘油三酯(p pp Fas和Scd1)和胆固醇代谢基因(Hmgcr、Hmgcs和Abca1)水平显著降低。此外,SA的添加改变了肠道微生物群,显著增加了Oscillospira (p副杆菌属p)的丰度
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引用次数: 0
Effects of the Mediterranean diet on the secondary prevention of cardiovascular diseases: a systematic review of randomised controlled trials. 地中海饮食对心血管疾病二级预防的影响:随机对照试验的系统回顾
IF 3.3 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-05-01 Epub Date: 2025-02-26 DOI: 10.1080/09637486.2025.2466111
Roghayeh Molani-Gol, Maryam Rafraf

This systematic review aimed to summarise the current knowledge regarding the effects of the Mediterranean diet (MD) on the secondary prevention of cardiovascular diseases (CVDs). A systematic search was done on Web of Sciences, PubMed, Scopus, and Google Scholar databases until January 2025. The majority of the included studies (15 of 16 RCTs) supported the role of MD following in the secondary prevention of CVDs. According to the RCT results, the patients in the MD group had lower cardiovascular deaths, non-fatal myocardial infarction, and other events. They also had healthier lipid profiles and blood fatty acids, higher flow-mediated dilation and endothelial progenitor cell levels, and lower endothelial progenitor cells compared to a low-fat diet. However, both MD and control (low-fat diet) groups promoted similar decreases in blood pressure and body mass index. The findings of this review suggested that adherence to the MD could be beneficial in the secondary prevention of CVD.

本系统综述旨在总结目前有关地中海饮食(Mediterranean diet,MD)对心血管疾病(CVDs)二级预防效果的知识。截至 2025 年 1 月,我们在 Web of Sciences、PubMed、Scopus 和 Google Scholar 数据库中进行了系统检索。纳入的大多数研究(16 项研究性试验中的 15 项)都支持采用地中海饮食对心血管疾病进行二级预防。根据临床试验结果,MD 组患者的心血管死亡、非致命性心肌梗死和其他事件发生率较低。与低脂饮食相比,他们的血脂状况和血液脂肪酸也更健康,血流介导的扩张和内皮祖细胞水平更高,而内皮祖细胞水平更低。不过,MD 组和对照组(低脂饮食)在降低血压和体重指数方面的效果相似。这项研究结果表明,坚持 MD 有助于心血管疾病的二级预防。
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引用次数: 0
Red lentil pasta quality and in vitro digestibility modulation by means of processing conditions. 加工条件对红扁豆面食品质及体外消化率的影响。
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-05-01 Epub Date: 2025-02-13 DOI: 10.1080/09637486.2025.2464665
Xinying Suo, Oscar Moreno-Araiza, Margherita Dall'Asta, Gianluca Giuberti, Alessio Marchesani, Elena Vittadini

Pulse pasta has, in recent years, gained the interest of consumers and food manufacturers and a deeper understanding of the the effects of flour types and pasta processing on its physical and nutritional characteristics has become a priority. This work investigates the effects of red lentil flour type (raw or pre-cooked), pasta extrusion pressure (i.e. 80 and 125 bars), and drying temperature (i.e.,50 and 80 °C) on pasta quality and in vitro nutritional digestibility. A significant reduction in cooking loss was found in pasta extruded at high pressure and dried at high temperature (80 °C), while all pasta had acceptable cooking quality in terms of length, thickness and weight gains. More slowly digestible starch was found in pasta dried at high temperatures, while less rapidly digestible and more resistant starch was present in pasta extruded at high pressure. In vitro starch digestibility can be effectively reduced by applying proper processing conditions (i.e. high extrusion pressure) which could be vital for designing a 100% legume pasta with modulated glycemic response.

近年来,脉冲面食引起了消费者和食品制造商的兴趣,更深入地了解面粉种类和面食加工对其物理和营养特性的影响已成为当务之急。本研究研究了红扁豆面粉类型(生的或预熟的)、面食挤压压力(即80和125巴)和干燥温度(即50和80°C)对面食质量和体外营养消化率的影响。在高压下挤压和高温(80°C)下干燥的意大利面可以显著减少烹饪损失,而所有意大利面在长度、厚度和重量增加方面都具有可接受的烹饪质量。在高温下干燥的面食中发现了更慢消化的淀粉,而在高压下挤压的面食中发现了更不容易消化和更耐消化的淀粉。在体外,通过适当的加工条件(即高挤压压力)可以有效地降低淀粉消化率,这对于设计具有调节血糖反应的100%豆类面食至关重要。
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引用次数: 0
Improving the structure of lentil proteins during fermentation and their association with nutritional values and solubility. 改善发酵过程中扁豆蛋白的结构及其与营养价值和溶解度的关系。
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-05-01 Epub Date: 2025-02-19 DOI: 10.1080/09637486.2025.2465763
Sofyan Maghaydah, Mohammad Alrosan, Muhammad H Alu'datt, Ammar A Razzak Mahmood, Sana Gammoh, Khalid Bani-Melhem, Farah R Al Qudsi, Thuan-Chew Tan, Ali Madi Almajwal, Ali Rashed Alshammari

Lentil proteins (LPs) may encounter challenges in their food industry applications due to certain limitations in their functional properties. This study focused on enhancing the quality of LPs through physical modifications and investigating the effects of a 24-hr fermentation process with Lactiplantibacillus plantarum. The protein structures of LPs were analysed using several techniques, including ultraviolet spectra, fluorescence spectra, and FT-IR spectra, respectively, resulting in the protein structure of LPs substantial modifications (p < 0.05) during the fermentation procedure. protein surface properties of fermented LPs, including surface charge and surface hydrophobicity, changed significantly (p < 0.05) from -23.03 to -32.70 mV and 860.30 to 600.6 a.u., respectively. Using Lactobacillus by fermentation processes can offer several benefits, particularly in enhancing the digestibility, protein structure, and nutritional values of LPs.

小扁豆蛋白(LPs)由于其功能特性的某些限制,在食品工业应用中可能会遇到挑战。本研究的重点是通过物理修饰来提高脂多糖的质量,并研究了植物乳杆菌24小时发酵过程的效果。利用紫外光谱、荧光光谱和FT-IR光谱等技术对LPs蛋白结构进行分析,发现LPs蛋白结构在发酵过程中发生了显著变化(p 0.05)。在-23.03 ~ -32.70 mV和860.30 ~ 600.6 a.u范围内,发酵LPs蛋白的表面特性(包括表面电荷和表面疏水性)发生了显著变化(p 0.05)。在发酵过程中使用乳酸杆菌可以提供一些好处,特别是在提高脂多糖的消化率、蛋白质结构和营养价值方面。
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引用次数: 0
Association between Healthy Eating Index 2015 and metabolic syndrome among US cancer survivors: evidence from NHANES 2005-2016. 2015年健康饮食指数与美国癌症幸存者代谢综合征之间的关系:来自NHANES 2005-2016的证据
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-05-01 Epub Date: 2025-02-05 DOI: 10.1080/09637486.2025.2461144
Jiazhen Yao, Xiaohong Chen, Yirong Xin, Fang Meng, Xiaoyan Zhong, Hanzhong Cao, Junlan Qiu, Xiaochen Shu

Our study examined the relationship between diet quality and the prevalence of metabolic syndrome (MetS) among 1779 U.S. cancer survivors using data from the National Health and Nutrition Examination Survey (NHANES, 2005-2016). Diet quality was assessed using the Healthy Eating Index 2015 (HEI-2015). Higher HEI-2015 scores were linked to significantly lower MetS prevalence (OR: 0.51, 95% CI: 0.32-0.80). Specifically, a higher intake of seafood and plant proteins, and fatty acids, coupled with a reduced intake of added sugars, was associated with decreased odds of MetS prevalence (OR: 0.93; 95% CI, 0.86-0.99) in cancer survivors. Additionally, a better diet quality was linked to lower prevalence of high waist circumference, elevated triglycerides, reduced high-density lipoprotein (HDL) cholesterol and high fasting glucose levels (OR, 0.44; 95% CI, 0.27-0.72). These results suggest that adopting healthy dietary habits may prevent MetS in cancer survivors.

我们的研究使用国家健康与营养检查调查(NHANES, 2005-2016)的数据,调查了1779名美国癌症幸存者的饮食质量与代谢综合征(MetS)患病率之间的关系。采用健康饮食指数2015 (HEI-2015)评估饮食质量。较高的HEI-2015评分与显著较低的MetS患病率相关(OR: 0.51, 95% CI: 0.32-0.80)。具体而言,摄入更多的海鲜和植物蛋白以及脂肪酸,同时减少添加糖的摄入,与MetS患病率降低相关(OR: 0.93;95% CI, 0.86-0.99)。此外,良好的饮食质量与低腰围、高甘油三酯、低高密度脂蛋白(HDL)胆固醇和高空腹血糖水平(OR, 0.44;95% ci, 0.27-0.72)。这些结果表明,采用健康的饮食习惯可以预防癌症幸存者的MetS。
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引用次数: 0
Are knowledge, attitudes and practices about dietary supplements and nutraceuticals related with exercise practice and setting? A cross-sectional study among Italian adults. 关于膳食补充剂和营养保健品的知识、态度和实践是否与锻炼实践和环境有关?意大利成年人的横断面研究。
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-03-01 Epub Date: 2024-12-09 DOI: 10.1080/09637486.2024.2437468
Patrizia Calella, Mirella Di Dio, Concetta Paola Pelullo, Gabriella Di Giuseppe, Vincenza Sansone, Fabrizio Liguori, Valeria Di Onofrio, Giuliana Valerio, Giorgio Liguori, Francesca Gallè

This cross-sectional study was aimed to investigate knowledge, attitudes, and practices regarding dietary supplements (DS) and nutraceuticals among athletes, gym practitioners, and individuals who did not exercise regularly. A total of 372 participants, aged 18-65, completed a questionnaire covering demographics, supplement usage, and three validated tools: the Knowledge about Dietary Supplements (KaDS), Supplements Knowledge Score (SKS), and Knowledge, Attitude, and Practice towards Nutraceuticals (KAPN). Significant differences were found in the use of vitaminised water, protein powder, glucosamines, beetroot juice, creatine, omega-3, and pre-workout supplements among the groups, with gym practitioners reporting the highest usage. Athletes scored the highest in knowledge of DS effects on health, while both athletes and gym practitioners scored higher than non-exercisers in knowledge related to sports supplements. However, all groups showed inadequate knowledge of nutraceuticals, and moderately positive attitudes towards these products. Older participants performed better in knowledge questionnaires. These findings suggest that gym practitioners, inactive and young people could benefit most from educational interventions regarding dietary supplementation.

这项横断面研究旨在调查运动员、健身房从业人员和非经常锻炼者对膳食补充剂(DS)和营养保健品的认识、态度和做法。共有 372 名年龄在 18-65 岁之间的参与者填写了一份调查问卷,内容包括人口统计学、补充剂使用情况以及三种经过验证的工具:膳食补充剂知识(KaDS)、补充剂知识评分(SKS)和对营养保健品的知识、态度和做法(KAPN)。结果发现,各组在维生素水、蛋白粉、葡糖胺、甜菜根汁、肌酸、欧米茄-3 和运动前补充剂的使用上存在显著差异,其中健身房从业人员的使用率最高。运动员对 DS 对健康影响的了解程度最高,而运动员和健身房从业者对运动补充剂的了解程度均高于非运动员。不过,所有群体对营养保健品的了解都不够,对这些产品的态度也都比较积极。年龄较大的参与者在知识问卷调查中表现较好。这些研究结果表明,健身房从业人员、非运动者和年轻人可以从有关膳食补充剂的教育干预中获益最多。
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引用次数: 0
The gut microbiome across the lifespan: how diet modulates our microbial ecosystem from infancy to the elderly. 整个生命周期的肠道微生物群:饮食如何调节我们从婴儿期到老年的微生物生态系统。
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-03-01 Epub Date: 2024-12-19 DOI: 10.1080/09637486.2024.2437472
Hazem Golshany, Shahinaz Ahmed Helmy, Nashwa Fathy Sayed Morsy, Aya Kamal, Qun Yu, Liuping Fan

This comprehensive review examines the impact of dietary patterns on gut microbiome composition and diversity from infancy to old age, linking these changes to age-related health outcomes. It investigates how the gut microbiome develops and changes across life stages, focusing on the influence of dietary factors. The review explores how early-life feeding practices, including breastfeeding and formula feeding, shape the infant gut microbiota and have lasting effects. In elderly individuals, alterations in the gut microbiome are associated with increased susceptibility to infections, chronic inflammation, metabolic disorders and cognitive decline. The critical role of diet in modulating the gut microbiome throughout life is emphasised, particularly the potential benefits of probiotics and fortified foods in promoting healthy ageing. By elucidating the mechanisms connecting food systems to gut health, this review provides insights into interventions that could enhance gut microbiome resilience and improve health outcomes across the lifespan.

这项综合综述研究了饮食模式对婴儿期至老年期肠道微生物组组成和多样性的影响,并将这些变化与年龄相关的健康结果联系起来。它研究肠道微生物群如何在生命阶段发展和变化,重点关注饮食因素的影响。该综述探讨了包括母乳喂养和配方奶喂养在内的生命早期喂养做法如何塑造婴儿肠道微生物群并产生持久影响。在老年人中,肠道微生物群的改变与感染、慢性炎症、代谢紊乱和认知能力下降的易感性增加有关。强调了饮食在调节肠道微生物群中的关键作用,特别是益生菌和强化食品在促进健康老龄化方面的潜在益处。通过阐明将食物系统与肠道健康联系起来的机制,本综述提供了可以增强肠道微生物群弹性和改善整个生命周期健康结果的干预措施的见解。
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引用次数: 0
Whole grapes or grape products on body weight, anthropometrics, and adipokines: systematic review and meta-analysis of randomized controlled trials. 全葡萄或葡萄制品对体重、人体测量学和脂肪因子的影响:随机对照试验的系统评价和荟萃分析。
IF 3.3 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-03-01 Epub Date: 2025-01-12 DOI: 10.1080/09637486.2024.2449037
Sepideh Soltani, Farzaneh Asoudeh, Maryam Motallaei, Roya Kolahdouz-Mohammadi, Scott C Forbes, Shima Abdollahi

This meta-analysis aims to compile all randomised controlled trials (RCTs) that examined the effects of grapes or grape products on adult anthropometric measures and serum adipokines. We searched PubMed, Scopus, Google scholar, Web of Science and CENTRAL databases published before January 2022. Random-effects model was used to combine mean differences between intervention and placebo groups. A minimal reduction was revealed for BMI following consumption of grapes/grape products [weighted mean difference (WMD): -0.14 kg]; however, no significant effects were observed on body weight, except for trials conducting in female (n = 3 studies; WMD: -0.68 kg), and those enrolled patients with metabolic syndrome (n = 3 studies; WMD: -0.62 kg). No significant effect was found for waist circumference, body fat, waist to hip ratio, serum level of leptin and adiponectin. Our findings showed that grapes or grape products have no significant anti-obesity effects on body weight, anthropometric measures, or adipokines. However, BMI showed a trivial decrease, which should not be considered given the low quality of the studies.

本荟萃分析旨在汇编所有研究葡萄或葡萄制品对成人人体测量指标和血清脂肪因子影响的随机对照试验(RCT)。我们检索了 2022 年 1 月之前发表的 PubMed、Scopus、Google scholar、Web of Science 和 CENTRAL 数据库。采用随机效应模型合并干预组和安慰剂组之间的平均差异。结果表明,食用葡萄/葡萄制品后,体重指数(BMI)的降低幅度很小[加权平均差(WMD):-0.14 千克];然而,除了针对女性(3 项研究;WMD:-0.68 千克)和代谢综合征患者(3 项研究;WMD:-0.62 千克)的试验外,未观察到对体重的显著影响。腰围、体脂、腰臀比、血清瘦素和脂肪连通素水平均无明显影响。我们的研究结果表明,葡萄或葡萄制品对体重、人体测量指标或脂肪因子没有明显的抗肥胖作用。不过,体重指数(BMI)的下降幅度微不足道,鉴于研究质量不高,不应将其视为影响因素。
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引用次数: 0
Anthocyanins for vascular health: plausible role of gut microbiota. 花青素对血管健康:肠道微生物群的合理作用。
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-03-01 Epub Date: 2025-03-10 DOI: 10.1080/09637486.2025.2475332
Giuseppe Grosso
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引用次数: 0
Maternal kefir intake during lactation impacts the breast milk and gut microbiota of the Wistar rat's offspring. 哺乳期间母体克非尔的摄入对Wistar大鼠后代的母乳和肠道微生物群有影响。
IF 3.5 2区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-03-01 Epub Date: 2025-02-03 DOI: 10.1080/09637486.2025.2461142
Thaís Costa de Almeida, Yasmin Neves Vieira Sabino, Poliana Guiomar de Almeida Brasiel, Beatriz Macedo de Oliveira Rocha, Gabriela de Cássia Ávila Alpino, Vinícius Novaes Rocha, Vanessa Cordeiro Dias, Cláudio Galuppo Diniz, Aline Dias Paiva, Vânia Lúcia da Silva, Julliane Dutra Medeiros, Sheila Cristina Potente Dutra Luquetti, Alessandra Barbosa Ferreira Machado

Environmental factors can play fundamental role in health in childhood and adulthood during critical developmental periods like lactation. The maternal intake of probiotics like kefir during lactation could benefit newborns' intestinal health. This study aimed to evaluate the effects of maternal kefir intake during lactation on bacterial breast milk composition and the gut microbiota of offspring Wistar male rats at weaning. Lactating Wistar rats and their pups were divided into four groups based on litter size and maternal kefir intake. Sequencing of the 16S rRNA gene in breast milk revealed the predominance of the Proteobacteria, Firmicutes, and Actinobacteriota phyla. Offspring gut microbiota exhibited clustering tendencies in kefir groups with varying genus abundance. Additionally, maternal kefir intake led to increased levels of butyrate acid in offspring faeces (> +30%, p > 0.05). These findings show that the lactation period could be a window of opportunity to program intestinal health through microbiota modulation.

在哺乳期等关键发育时期,环境因素对儿童和成年期的健康起着重要作用。母亲在哺乳期摄入克非尔等益生菌有利于新生儿肠道健康。本研究旨在评估哺乳期间母体摄入克非尔对断奶Wistar雄性大鼠后代细菌母乳组成和肠道微生物群的影响。将哺乳期Wistar大鼠及其幼崽按产仔数和母鼠克菲尔摄入量分为4组。母乳中16S rRNA基因测序显示,变形菌门、厚壁菌门和放线菌门占主导地位。子代肠道菌群在不同属丰度的克非尔组中呈现聚类趋势。此外,母体摄入克非尔导致子代粪便中丁酸水平升高(> +30%,p >0.05)。这些发现表明,哺乳期可能是通过调节微生物群来规划肠道健康的机会之窗。
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引用次数: 0
期刊
International Journal of Food Sciences and Nutrition
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