Pub Date : 2024-05-01Epub Date: 2024-01-30DOI: 10.1080/09637486.2024.2306296
Elaine Cristina de Almeida Kotchetkoff, Fabiola Isabel Suano-Souza, Daniela Neri Gama de Almeida, Talita Lemos Neves Barreto, Raquel Bicudo Mendonça, Roseli Oselka Saccardo Sarni
This study aimed to describe the dietary intake of ultra-processed foods (UPF) by children and adolescents with food allergy (FA) and to verify a possible association between the UPF intake with clinical characteristics and nutritional status in this group. This cross-sectional study included 110 children and adolescents with single or multiple FA IgE and non-IgE mediated. We evaluated food intake using the NOVA classification through the three 24-h recalls. The average contribution of UPF to total energy intake (calories) ranges from 21% in the first quartile to 43% in the last quartile (mean UPF intake 33.9 ± 14.9%). After binary logistic regression, an association was verified between dietary intake of UPF (>4th quartile) as a percentage of total energy intake and having multiple food allergies (OR 4.102; 95% CI - 1.331 to 12.643; p = .014). We concluded that children and adolescents with FA consumed a higher amount of UPF.
本研究旨在描述患有食物过敏症(FA)的儿童和青少年从膳食中摄入超加工食品(UPF)的情况,并验证该群体的超加工食品摄入量与临床特征和营养状况之间可能存在的关联。这项横断面研究纳入了 110 名患有 IgE 和非 IgE 介导的单一或多种 FA 的儿童和青少年。我们采用诺瓦分类法对食物摄入量进行了评估,并进行了三次 24 小时回顾。UPF对总能量摄入量(卡路里)的平均贡献率从第一四分位数的21%到最后四分位数的43%不等(平均UPF摄入量为33.9 ± 14.9%)。经过二元逻辑回归,证实了膳食中 UPF 摄入量(>第 4 个四分位数)占总能量摄入量的百分比与多种食物过敏之间存在关联(OR 4.102;95% CI - 1.331 至 12.643;P = .014)。我们的结论是,患有 FA 的儿童和青少年摄入的 UPF 量较高。
{"title":"Ultra-processed food intake and food allergy in children and adolescents.","authors":"Elaine Cristina de Almeida Kotchetkoff, Fabiola Isabel Suano-Souza, Daniela Neri Gama de Almeida, Talita Lemos Neves Barreto, Raquel Bicudo Mendonça, Roseli Oselka Saccardo Sarni","doi":"10.1080/09637486.2024.2306296","DOIUrl":"10.1080/09637486.2024.2306296","url":null,"abstract":"<p><p>This study aimed to describe the dietary intake of ultra-processed foods (UPF) by children and adolescents with food allergy (FA) and to verify a possible association between the UPF intake with clinical characteristics and nutritional status in this group. This cross-sectional study included 110 children and adolescents with single or multiple FA IgE and non-IgE mediated. We evaluated food intake using the NOVA classification through the three 24-h recalls. The average contribution of UPF to total energy intake (calories) ranges from 21% in the first quartile to 43% in the last quartile (mean UPF intake 33.9 ± 14.9%). After binary logistic regression, an association was verified between dietary intake of UPF (>4th quartile) as a percentage of total energy intake and having multiple food allergies (OR 4.102; 95% CI - 1.331 to 12.643; <i>p</i> = .014). We concluded that children and adolescents with FA consumed a higher amount of UPF.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"317-324"},"PeriodicalIF":3.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139642095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01Epub Date: 2024-02-12DOI: 10.1080/09637486.2024.2313979
Sofia Lotti, Antonia Napoletano, Marta Tristan Asensi, Giuditta Pagliai, Ilaria Giangrandi, Barbara Colombini, Monica Dinu, Francesco Sofi
Despite the many well-documented benefits of the Mediterranean diet (MD), many Mediterranean countries seem to be moving away from it. The aim of this study was to investigate the MD adherence in 10,916 adults who completed the validated Medi-Lite questionnaire from January 2019 to December 2022 in Italy, and to assess the consumption of its food groups by comparing them with current national dietary guidelines. The sample showed a good level of MD adherence (12 ± 2.5). However, from 2019 to 2022, a significant (p < 0.001) decline in the adherence level emerged. An overconsumption of fresh red meat, cheese and poultry compared to dietary guidelines was observed. In contrast, an under-consumption of vegetables, bread, legumes, fish and milk and dairy products emerged. In recent years, a decline in MD adherence was observed in Italy, probably determined by an excessive consumption of animal products.
{"title":"Assessment of Mediterranean diet adherence and comparison with Italian dietary guidelines: a study of over 10,000 adults from 2019 to 2022.","authors":"Sofia Lotti, Antonia Napoletano, Marta Tristan Asensi, Giuditta Pagliai, Ilaria Giangrandi, Barbara Colombini, Monica Dinu, Francesco Sofi","doi":"10.1080/09637486.2024.2313979","DOIUrl":"10.1080/09637486.2024.2313979","url":null,"abstract":"<p><p>Despite the many well-documented benefits of the Mediterranean diet (MD), many Mediterranean countries seem to be moving away from it. The aim of this study was to investigate the MD adherence in 10,916 adults who completed the validated Medi-Lite questionnaire from January 2019 to December 2022 in Italy, and to assess the consumption of its food groups by comparing them with current national dietary guidelines. The sample showed a good level of MD adherence (12 ± 2.5). However, from 2019 to 2022, a significant (<i>p</i> < 0.001) decline in the adherence level emerged. An overconsumption of fresh red meat, cheese and poultry compared to dietary guidelines was observed. In contrast, an under-consumption of vegetables, bread, legumes, fish and milk and dairy products emerged. In recent years, a decline in MD adherence was observed in Italy, probably determined by an excessive consumption of animal products.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"336-343"},"PeriodicalIF":3.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139722480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01Epub Date: 2024-01-17DOI: 10.1080/09637486.2024.2303043
Maria Elena Navarra, Floriana Bertaina, Alessandro Piedimonte, Alessandro Mauro, Federica Scarpina
Impulsivity is known to influence food choices. We explored possible differences in its expression between individuals with or without an eco-sustainable diet and its relationship with cognitions and behaviours about eco-sustainable foods. Participants were categorised as having or not having an eco-sustainable diet. Impulsivity traits and cognitions and behaviours about sustainable food products were measured. Among the 332 participants, 92.78% showed an eco-sustainable diet, whereas only 7.22% had an eco-sustainable diet. No difference between groups emerged about impulsive traits, whereas significant differences emerged in cognitions and behaviours about sustainable foods, with the only exceptions of subjective norms and past behaviour. Impulsive traits were linked to cognitions and behaviours differently within groups. Impulsivity traits may be related to actions towards eco-sustainable foods, with the perception of their availability playing a crucial role. Increasing contextual opportunities may be fundamental for having eco-sustainable consumers.
{"title":"Are eco-sustainable dietary patterns associated with impulsiveness? An insight from Italy.","authors":"Maria Elena Navarra, Floriana Bertaina, Alessandro Piedimonte, Alessandro Mauro, Federica Scarpina","doi":"10.1080/09637486.2024.2303043","DOIUrl":"10.1080/09637486.2024.2303043","url":null,"abstract":"<p><p>Impulsivity is known to influence food choices. We explored possible differences in its expression between individuals with or without an eco-sustainable diet and its relationship with cognitions and behaviours about eco-sustainable foods. Participants were categorised as having or not having an eco-sustainable diet. Impulsivity traits and cognitions and behaviours about sustainable food products were measured. Among the 332 participants, 92.78% showed an eco-sustainable diet, whereas only 7.22% had an eco-sustainable diet. No difference between groups emerged about impulsive traits, whereas significant differences emerged in cognitions and behaviours about sustainable foods, with the only exceptions of subjective norms and past behaviour. Impulsive traits were linked to cognitions and behaviours differently within groups. Impulsivity traits may be related to actions towards eco-sustainable foods, with the perception of their availability playing a crucial role. Increasing contextual opportunities may be fundamental for having eco-sustainable consumers.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"277-292"},"PeriodicalIF":3.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139478294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01Epub Date: 2024-04-30DOI: 10.1080/09637486.2024.2345691
Giuseppe Grosso
{"title":"The underrated role of psychosocial determinants of dietary choices.","authors":"Giuseppe Grosso","doi":"10.1080/09637486.2024.2345691","DOIUrl":"10.1080/09637486.2024.2345691","url":null,"abstract":"","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"239-240"},"PeriodicalIF":3.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140851282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-01Epub Date: 2024-02-25DOI: 10.1080/09637486.2024.2314676
Markos Makiso Urugo, Tilahun A Teka, Tefera Belachew Lema, Janerose Nasimiyu Lusweti, Jasmina Djedjibegovíc, Carl Lachat, Kokeb Tesfamariam, Addisalem Mesfin, Tess Astatkie, Mosaad A Abdel-Wahhab
Childhood stunting is a global phenomenon affecting more than 149 million children under the age of 5 worldwide. Exposure to aflatoxins (AFs) in utero, during breastfeeding, and consumption of contaminated food affect the gut microbiome, resulting in intestinal dysfunction and potentially contributing to stunting. This review explores the potential relationship between AF exposure, environmental enteropathy and childhood stunting. AFs bind to DNA, disrupt protein synthesis and elicit environmental enteropathy (EE). An EE alters the structure of intestinal epithelial cells, impairs nutrient uptake and leads to malabsorption. This article proposes possible intervention strategies for researchers and policymakers to reduce AF exposure, EE and childhood stunting, such as exposure reduction, the implementation of good agricultural practices, dietary diversification and improving environmental water sanitation and hygiene.
{"title":"Dietary aflatoxins exposure, environmental enteropathy, and their relation with childhood stunting.","authors":"Markos Makiso Urugo, Tilahun A Teka, Tefera Belachew Lema, Janerose Nasimiyu Lusweti, Jasmina Djedjibegovíc, Carl Lachat, Kokeb Tesfamariam, Addisalem Mesfin, Tess Astatkie, Mosaad A Abdel-Wahhab","doi":"10.1080/09637486.2024.2314676","DOIUrl":"10.1080/09637486.2024.2314676","url":null,"abstract":"<p><p>Childhood stunting is a global phenomenon affecting more than 149 million children under the age of 5 worldwide. Exposure to aflatoxins (AFs) <i>in utero</i>, during breastfeeding, and consumption of contaminated food affect the gut microbiome, resulting in intestinal dysfunction and potentially contributing to stunting. This review explores the potential relationship between AF exposure, environmental enteropathy and childhood stunting. AFs bind to DNA, disrupt protein synthesis and elicit environmental enteropathy (EE). An EE alters the structure of intestinal epithelial cells, impairs nutrient uptake and leads to malabsorption. This article proposes possible intervention strategies for researchers and policymakers to reduce AF exposure, EE and childhood stunting, such as exposure reduction, the implementation of good agricultural practices, dietary diversification and improving environmental water sanitation and hygiene.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"241-254"},"PeriodicalIF":3.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139971798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-19DOI: 10.1080/09637486.2024.2335523
Laila Eleraky, Wolfgang Stuetz, Constance Rybak, Jan Frank, Hans Konrad Biesalski, Hadijah Mbwana, Joyce Kinabo, Christine Lambert
The aim of this study was to evaluate the accuracy of nutrient intake assessment with the food group-based algorithm “Calculator of Inadequate Micronutrient Intake” (CIMI) in comparison to the esta...
{"title":"Potentials and limitations of a food group-based algorithm to assess dietary nutrient intake of women in rural areas in Tanzania","authors":"Laila Eleraky, Wolfgang Stuetz, Constance Rybak, Jan Frank, Hans Konrad Biesalski, Hadijah Mbwana, Joyce Kinabo, Christine Lambert","doi":"10.1080/09637486.2024.2335523","DOIUrl":"https://doi.org/10.1080/09637486.2024.2335523","url":null,"abstract":"The aim of this study was to evaluate the accuracy of nutrient intake assessment with the food group-based algorithm “Calculator of Inadequate Micronutrient Intake” (CIMI) in comparison to the esta...","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":"1 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2024-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140630951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-04DOI: 10.1080/09637486.2024.2335524
Vincenza Gianfredi, Lorenzo Stacchini, Sofia Lotti, Iris Sarno, Francesco Sofi, Monica Dinu
Sustainability is crucial for transforming the food system, addressing environmental and nutrition issues and depends on consumer perceptions and values. This cross-sectional study investigates the...
{"title":"Knowledge, attitude and behaviours towards food sustainability in a group of Italian consumers. A cross-sectional study","authors":"Vincenza Gianfredi, Lorenzo Stacchini, Sofia Lotti, Iris Sarno, Francesco Sofi, Monica Dinu","doi":"10.1080/09637486.2024.2335524","DOIUrl":"https://doi.org/10.1080/09637486.2024.2335524","url":null,"abstract":"Sustainability is crucial for transforming the food system, addressing environmental and nutrition issues and depends on consumer perceptions and values. This cross-sectional study investigates the...","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":"109 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140577597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The production and diversity of the supply of food products has grown exponentially in recent decades, along with the increase in cardiovascular diseases associated with poor diet. Among the factors, one of the most important is the lack of information for the consumer when purchasing. The present work evaluates the impact of implementing the traffic light labelling of foods in reducing deaths due to Noncommunicable Diseases (NCD). Econometric techniques of two-way effects panel data from 21 Ecuadorian provinces taken from official sources for the analysis period 2010-2019. For Ecuador, a favourable impact was found in the reduction of the NCD mortality rate, especially in the last three years; in 2017, it was reduced by 0.129%, in 2018 by 0.305%, and in 2019 by 0.289%. An implication of economic policy is the advertising regulation of products that may affect health, strengthening surveillance and sanctioning companies that fail to comply with the regulation.
{"title":"Incidence of traffic light labelling on noncommunicable diseases: a roadmap for achieving sustainable development.","authors":"Michelle López-Sánchez, Yenny Moreno-Salazar, Josselyn Cuenca, Jackeline Ortega, Rubén Román-Aguirre","doi":"10.1080/09637486.2023.2280503","DOIUrl":"10.1080/09637486.2023.2280503","url":null,"abstract":"<p><p>The production and diversity of the supply of food products has grown exponentially in recent decades, along with the increase in cardiovascular diseases associated with poor diet. Among the factors, one of the most important is the lack of information for the consumer when purchasing. The present work evaluates the impact of implementing the traffic light labelling of foods in reducing deaths due to Noncommunicable Diseases (NCD). Econometric techniques of two-way effects panel data from 21 Ecuadorian provinces taken from official sources for the analysis period 2010-2019. For Ecuador, a favourable impact was found in the reduction of the NCD mortality rate, especially in the last three years; in 2017, it was reduced by 0.129%, in 2018 by 0.305%, and in 2019 by 0.289%. An implication of economic policy is the advertising regulation of products that may affect health, strengthening surveillance and sanctioning companies that fail to comply with the regulation.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"185-196"},"PeriodicalIF":3.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138046789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01Epub Date: 2023-11-29DOI: 10.1080/09637486.2023.2283688
Bianca Papotti, Mattia Dessena, Maria Pia Adorni, Davide Paleari, Laura Rinaldi, Franco Bernini
Immune system (IS) functionality is warranted by inter-dependent processes that balance body defences without exceeding in inflammation. An ideal nutraceutical approach should sustain the protective IS activity while controlling inflammation. The potential immunomodulatory activity of the food supplement (FS) AminoDefence was studied in resting macrophages RAW264.7 and following stimulation of bacterial- and viral-associated inflammation trough LPS and PolyI:C treatments, respectively. In unstimulated macrophages, the formulation exerted a dose-dependent immunostimulant activity by up-regulating NO, IL-6, TNF-α and MCP-1 release, while it dampened the aberrant release of these factors induced by pro-inflammatory stimuli. Exploring the contribution of single components Echinacea purpurea (E. purpurea) extract and quercetin, used at proportional concentrations than in whole formulation, a more pronounced immunostimulant effect was observed for E. purpurea, and an anti-inflammatory activity for quercetin. Hence, AminoDefence exerts an immunomodulatory activity in macrophages by effectively stimulating a protective inflammatory response and limiting it in cases of excessive inflammation.
{"title":"<i>In vitro</i> evaluation of the immunomodulatory activity of the nutraceutical formulation AminoDefence.","authors":"Bianca Papotti, Mattia Dessena, Maria Pia Adorni, Davide Paleari, Laura Rinaldi, Franco Bernini","doi":"10.1080/09637486.2023.2283688","DOIUrl":"10.1080/09637486.2023.2283688","url":null,"abstract":"<p><p>Immune system (IS) functionality is warranted by inter-dependent processes that balance body defences without exceeding in inflammation. An ideal nutraceutical approach should sustain the protective IS activity while controlling inflammation. The potential immunomodulatory activity of the food supplement (FS) AminoDefence was studied in resting macrophages RAW264.7 and following stimulation of bacterial- and viral-associated inflammation trough LPS and PolyI:C treatments, respectively. In unstimulated macrophages, the formulation exerted a dose-dependent immunostimulant activity by up-regulating NO, IL-6, TNF-α and MCP-1 release, while it dampened the aberrant release of these factors induced by pro-inflammatory stimuli. Exploring the contribution of single components <i>Echinacea purpurea</i> (<i>E. purpurea</i>) extract and quercetin, used at proportional concentrations than in whole formulation, a more pronounced immunostimulant effect was observed for <i>E. purpurea,</i> and an anti-inflammatory activity for quercetin. Hence, AminoDefence exerts an immunomodulatory activity in macrophages by effectively stimulating a protective inflammatory response and limiting it in cases of excessive inflammation.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"173-184"},"PeriodicalIF":3.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138459853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-01Epub Date: 2023-12-19DOI: 10.1080/09637486.2023.2294682
Yi-Seul Jo, Jeong-Hwa Choi
Bitterness-receptor gene TAS2R38 is associated with taste sensitivity and dietary behaviour, and is known to play a critical role in adiposity. However, evidence regarding body composition from a large cohort is lacking. This study aimed to ascertain whether TAS2R38 rs10246939 C > T bitterness genetic variation is associated with body composition in Korean individuals. The TAS2R38 rs10246939 genotypes, anthropometric measurements, and body composition of 1,843 males and 1,801 females from the Korean Genome and Epidemiology Study were analysed. Findings suggested that there was a significant difference in body fat components by TAS2R38 genotype. Furthermore, the bitterness genotype exhibited a positive association with adiposity markers in females. The TT genotype showed greater body mass index, body fat percentage, and degree of obesity than those with the C allele. However, such an association was not observed in males. In conclusion, this study suggests that TAS2R38 rs10246939 is associated with fat tissue markers in Korean females.
苦味受体基因 TAS2R38 与味觉敏感性和饮食行为有关,并且已知在肥胖中起着关键作用。然而,目前还缺乏来自大型队列的有关身体组成的证据。本研究旨在确定 TAS2R38 rs10246939 C > T 苦味基因变异是否与韩国人的身体成分有关。研究分析了韩国基因组与流行病学研究中 1,843 名男性和 1,801 名女性的 TAS2R38 rs10246939 基因型、人体测量数据和身体成分。研究结果表明,TAS2R38 基因型在体脂成分方面存在显著差异。此外,苦味基因型与女性的脂肪指标呈正相关。TT 基因型比 C 等位基因型显示出更高的体重指数、体脂百分比和肥胖程度。然而,在男性中却没有观察到这种关联。总之,这项研究表明,TAS2R38 rs10246939 与韩国女性的脂肪组织指标有关。
{"title":"Genetic variation in <i>TAS2R38</i> bitterness receptor is associated with body composition in Korean females.","authors":"Yi-Seul Jo, Jeong-Hwa Choi","doi":"10.1080/09637486.2023.2294682","DOIUrl":"10.1080/09637486.2023.2294682","url":null,"abstract":"<p><p>Bitterness-receptor gene <i>TAS2R38</i> is associated with taste sensitivity and dietary behaviour, and is known to play a critical role in adiposity. However, evidence regarding body composition from a large cohort is lacking. This study aimed to ascertain whether <i>TAS2R38</i> rs10246939 C > T bitterness genetic variation is associated with body composition in Korean individuals. The <i>TAS2R38</i> rs10246939 genotypes, anthropometric measurements, and body composition of 1,843 males and 1,801 females from the Korean Genome and Epidemiology Study were analysed. Findings suggested that there was a significant difference in body fat components by <i>TAS2R38</i> genotype. Furthermore, the bitterness genotype exhibited a positive association with adiposity markers in females. The TT genotype showed greater body mass index, body fat percentage, and degree of obesity than those with the C allele. However, such an association was not observed in males. In conclusion, this study suggests that <i>TAS2R38</i> rs10246939 is associated with fat tissue markers in Korean females.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"197-206"},"PeriodicalIF":3.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138800139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}