Pub Date : 2024-06-03DOI: 10.11648/j.ijmsa.20241303.12
Mahshid Sadeghi
Breast cancer is the most commonly diagnosed form of cancer globally, with women having a higher risk of developing the disease. Current treatment approaches, such as surgery, chemotherapy, and radiotherapy, encounter significant difficulties due to the heterogeneous and intricate regulation of tumors. Nanotechnology, especially the utilization of graphene oxide (GO), presents a promising approach to overcoming the limitations of traditional treatments. GO's unique properties, including its two-dimensional structure, functional groups, and high surface area, make it an ideal material for developing multifunctional nanocarriers. Graphene oxide-based nanocarriers have demonstrated immense potential in breast cancer therapeutics by overcoming the limitations and adverse reactions associated with chemotherapy. The functionalization of GO's surface using biocompatible substances like chitosan and polyethylene glycol improves the cytotoxicity of GO. Enhancing the cytotoxicity also improves the ability to treat tumors that have developed resistance to traditional treatments. These findings demonstrate the promising efficacy of GO-based nanocarriers in treating breast cancer and pave the way for the development of more precise and efficient treatment strategies in the future, potentially improving therapeutic outcomes.
乳腺癌是全球最常见的癌症，女性患病风险较高。目前的治疗方法，如手术、化疗和放疗，由于肿瘤的异质性和错综复杂的调节，都遇到了很大的困难。纳米技术，尤其是氧化石墨烯（GO）的利用，为克服传统治疗方法的局限性提供了一种前景广阔的方法。氧化石墨烯的独特性质，包括二维结构、功能基团和高表面积，使其成为开发多功能纳米载体的理想材料。基于氧化石墨烯的纳米载体克服了化疗的局限性和不良反应，在乳腺癌治疗中展现出巨大的潜力。使用壳聚糖和聚乙二醇等生物相容性物质对 GO 表面进行功能化，可提高 GO 的细胞毒性。增强细胞毒性还能提高治疗对传统疗法产生抗药性的肿瘤的能力。这些研究结果表明，基于GO的纳米载体在治疗乳腺癌方面具有良好的疗效，并为今后开发更精确、更高效的治疗策略铺平了道路，从而有可能改善治疗效果。
{"title":"Graphene Oxide Nanocarriers for Effective Drug Delivery in Breast Cancer Treatment","authors":"Mahshid Sadeghi","doi":"10.11648/j.ijmsa.20241303.12","DOIUrl":"https://doi.org/10.11648/j.ijmsa.20241303.12","url":null,"abstract":"Breast cancer is the most commonly diagnosed form of cancer globally, with women having a higher risk of developing the disease. Current treatment approaches, such as surgery, chemotherapy, and radiotherapy, encounter significant difficulties due to the heterogeneous and intricate regulation of tumors. Nanotechnology, especially the utilization of graphene oxide (GO), presents a promising approach to overcoming the limitations of traditional treatments. GO's unique properties, including its two-dimensional structure, functional groups, and high surface area, make it an ideal material for developing multifunctional nanocarriers. Graphene oxide-based nanocarriers have demonstrated immense potential in breast cancer therapeutics by overcoming the limitations and adverse reactions associated with chemotherapy. The functionalization of GO's surface using biocompatible substances like chitosan and polyethylene glycol improves the cytotoxicity of GO. Enhancing the cytotoxicity also improves the ability to treat tumors that have developed resistance to traditional treatments. These findings demonstrate the promising efficacy of GO-based nanocarriers in treating breast cancer and pave the way for the development of more precise and efficient treatment strategies in the future, potentially improving therapeutic outcomes.\u0000","PeriodicalId":14116,"journal":{"name":"International Journal of Materials Science and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141388763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-10DOI: 10.11648/j.ijmsa.20241303.11
Daniel Mededji, Elie Sogbochi, Ayihaou Djossou, L. Fagbemi, Dominique Sohounhloue
The use of eco-materials for thermal insulation is becoming more and more recommended compared with synthetic materials. They have the advantage of being biodegradable and sometimes less expensive. To this end, the use of packaging with the function of hot preservatives but made from local and biodegradable materials is a very interesting alternative to synthetic enclosures. This work involved formulating eco-materials made from cow dung coatings and a mixture of cow dung coatings with a framework of fibres extracted from the stalks of oil palm leaves. In addition, to monitor the temperature rise in the various eco-materials manufactured and characterise them using the hot ribbon method to determine their effusivity and thermal conductivity. The pair of materials exposed to heating showed a gradual rise in temperature within the materials when the resistor was energised. A slightly faster rise was observed in the first fifty minutes. The results obtained indicate that the cow dung has a higher effusivity (E = 517.32 J.m-2. °C-1. s-1/2) than its composite (E = 501.20 J.m-2. °C-1. s-1/2). The thermal conductivity values obtained indicate that the cow dung has a higher thermal conductivity (λ'=0.19 W.m^(-1).K^(-1)) than that of the composite structure (λ=0.15 W.m^(-1).K^(-1)). From the above, the presence of the fibre frame has the effect of reducing thermal conductivity because it absorbs more energy. The materials produced therefore have proven insulating properties, which are improved when the framework is made from fibres extracted from the stalks of oil palm leaves. Using oil palm fibres in combination with cow dung as eco-materials for thermal insulation is an excellent alternative to synthetic insulation.
{"title":"Thermal Insulation of “akassa” Hot Preservation Baskets Using Cow Dung Coatings","authors":"Daniel Mededji, Elie Sogbochi, Ayihaou Djossou, L. Fagbemi, Dominique Sohounhloue","doi":"10.11648/j.ijmsa.20241303.11","DOIUrl":"https://doi.org/10.11648/j.ijmsa.20241303.11","url":null,"abstract":"The use of eco-materials for thermal insulation is becoming more and more recommended compared with synthetic materials. They have the advantage of being biodegradable and sometimes less expensive. To this end, the use of packaging with the function of hot preservatives but made from local and biodegradable materials is a very interesting alternative to synthetic enclosures. This work involved formulating eco-materials made from cow dung coatings and a mixture of cow dung coatings with a framework of fibres extracted from the stalks of oil palm leaves. In addition, to monitor the temperature rise in the various eco-materials manufactured and characterise them using the hot ribbon method to determine their effusivity and thermal conductivity. The pair of materials exposed to heating showed a gradual rise in temperature within the materials when the resistor was energised. A slightly faster rise was observed in the first fifty minutes. The results obtained indicate that the cow dung has a higher effusivity (E = 517.32 J.m<sup>-2</sup>. °C<sup>-1</sup>. s<sup>-1/2</sup>) than its composite (E = 501.20 J.m<sup>-2</sup>. °C<sup>-1</sup>. s<sup>-1/2</sup>). The thermal conductivity values obtained indicate that the cow dung has a higher thermal conductivity (λ'=0.19 W.m^(-1).K^(-1)) than that of the composite structure (λ=0.15 W.m^(-1).K^(-1)). From the above, the presence of the fibre frame has the effect of reducing thermal conductivity because it absorbs more energy. The materials produced therefore have proven insulating properties, which are improved when the framework is made from fibres extracted from the stalks of oil palm leaves. Using oil palm fibres in combination with cow dung as eco-materials for thermal insulation is an excellent alternative to synthetic insulation.\u0000","PeriodicalId":14116,"journal":{"name":"International Journal of Materials Science and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140992439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-17DOI: 10.11648/j.ijmsa.20241302.12
Abebayehu Abdela, Mieraf Asfaw, B. Buffel, Belete Sirahbizu, F. Desplentere
Lignocellulose fibers (Cellulosic fibers) are among the major agricultural resources from plant whose potentials are not exploited in some cases and/or underexploited in many cases. If their potentials for industrial application could be exploited, selling the fibers for manufacturing uses would be a win-win situation for both the industries and the farmers, and provide the latter with a much needed source of additional income since composite material reinforced with lignocellulose fibers can be used for diverse application including the production of parts in automotive industry. For this to be successful, it is mandatory to make fiber level characterization. In this process, there are various determinants that affects the characteristics of lignocellulose fiber including agro-ecological zone, plant age from which the fiber is extracted, lignocellulose structure, fiber extraction method and subsequent treatment to enhance properties. This review, therefore, presents the basics of lignocellulose fiber potential and insight into selected deliberation related to fiber level characterization in light of micromechanical analysis for new biocomposite under development. Included in this review, there are considerations to be potted during characterization at fiber level. For fiber diameter measurement and estimation, the following considerations are reported in this paper: measurement method validation, proper cross-section and fiber geometry assumption, lignocellulose structure and internal holes; enough sample consideration, incorporation of analytical method for cross checking. Likewise consideration during estimating fiber density, single fiber tensile strength and stiffness are review and discussed in this review.
{"title":"Review on Fundamental Considerations During Lignocellulosic Fiber Characterization in Light Micromechanical Analysis of Their Composites","authors":"Abebayehu Abdela, Mieraf Asfaw, B. Buffel, Belete Sirahbizu, F. Desplentere","doi":"10.11648/j.ijmsa.20241302.12","DOIUrl":"https://doi.org/10.11648/j.ijmsa.20241302.12","url":null,"abstract":"Lignocellulose fibers (Cellulosic fibers) are among the major agricultural resources from plant whose potentials are not exploited in some cases and/or underexploited in many cases. If their potentials for industrial application could be exploited, selling the fibers for manufacturing uses would be a win-win situation for both the industries and the farmers, and provide the latter with a much needed source of additional income since composite material reinforced with lignocellulose fibers can be used for diverse application including the production of parts in automotive industry. For this to be successful, it is mandatory to make fiber level characterization. In this process, there are various determinants that affects the characteristics of lignocellulose fiber including agro-ecological zone, plant age from which the fiber is extracted, lignocellulose structure, fiber extraction method and subsequent treatment to enhance properties. This review, therefore, presents the basics of lignocellulose fiber potential and insight into selected deliberation related to fiber level characterization in light of micromechanical analysis for new biocomposite under development. Included in this review, there are considerations to be potted during characterization at fiber level. For fiber diameter measurement and estimation, the following considerations are reported in this paper: measurement method validation, proper cross-section and fiber geometry assumption, lignocellulose structure and internal holes; enough sample consideration, incorporation of analytical method for cross checking. Likewise consideration during estimating fiber density, single fiber tensile strength and stiffness are review and discussed in this review.","PeriodicalId":14116,"journal":{"name":"International Journal of Materials Science and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140693402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this research, Polycaprolactone-graphene oxide Nanocomposite coating was synthesized and characterized by Electrospinning on Ti6AL4V alloy. In order to create a uniform coating with optimal thickness, the effective parameters of Electrospinning coating, including solvent, polymer concentration, and bioceramic percentage, were investigated. Also, the cytotoxicity and corrosion tests were evaluated by the electrochemical polarization test method of the created coating in comparisons and different percentages. In order to characterize the coating, a test such as a scanning electron microscope was used. The results showed that as much as the amount of Graphene oxide is increased, the diameter of Nanofibers decreases. The diameter of Polycaprolactone Nanofibers was 1.3 micrometers, which increases to 56.0 micrometers by adding Graphene oxide. The results of the corrosion test showed that the use of Nano composite coating increased the corrosion resistance to the size of the coating. The nanocomposite coating consists of polycaprolactone nanofibers and graphene oxide, which mimics the behavior of the extracellular matrix and improves the biological and antibacterial behavior of the titanium surface. So far, there has been no report on the creation of this fibrous nanocomposite coating on titanium. The results of the cytotoxicity test showed that the use of Nanocomposite coating has effectively reduced the cytotoxicity on the scaffolds. By creating a polycaprolactone-graphene oxide nanofiber composite coating, the biological and antibacterial properties of titanium alloy will be improved and its corrosion resistance will probably change. In this project, the main question is extracting effective parameters in creating a composite coating on titanium surface by electrospinning method and characterizing and biological evaluation of the created coating.
{"title":"Surface Modification of Ti-6Al-4V Alloy by Polycaprolactone-Graphene Oxide Composite Coating","authors":"Paria Fazlali, Mahrokh Tahernejad, Leila Biglari, Mahla Eslami","doi":"10.11648/j.ijmsa.20241302.11","DOIUrl":"https://doi.org/10.11648/j.ijmsa.20241302.11","url":null,"abstract":"In this research, Polycaprolactone-graphene oxide Nanocomposite coating was synthesized and characterized by Electrospinning on Ti6AL4V alloy. In order to create a uniform coating with optimal thickness, the effective parameters of Electrospinning coating, including solvent, polymer concentration, and bioceramic percentage, were investigated. Also, the cytotoxicity and corrosion tests were evaluated by the electrochemical polarization test method of the created coating in comparisons and different percentages. In order to characterize the coating, a test such as a scanning electron microscope was used. The results showed that as much as the amount of Graphene oxide is increased, the diameter of Nanofibers decreases. The diameter of Polycaprolactone Nanofibers was 1.3 micrometers, which increases to 56.0 micrometers by adding Graphene oxide. The results of the corrosion test showed that the use of Nano composite coating increased the corrosion resistance to the size of the coating. The nanocomposite coating consists of polycaprolactone nanofibers and graphene oxide, which mimics the behavior of the extracellular matrix and improves the biological and antibacterial behavior of the titanium surface. So far, there has been no report on the creation of this fibrous nanocomposite coating on titanium. The results of the cytotoxicity test showed that the use of Nanocomposite coating has effectively reduced the cytotoxicity on the scaffolds. By creating a polycaprolactone-graphene oxide nanofiber composite coating, the biological and antibacterial properties of titanium alloy will be improved and its corrosion resistance will probably change. In this project, the main question is extracting effective parameters in creating a composite coating on titanium surface by electrospinning method and characterizing and biological evaluation of the created coating.","PeriodicalId":14116,"journal":{"name":"International Journal of Materials Science and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140752833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.11648/ijmsa.20241301.12
Elsammani Ali Shokralla
{"title":"Dielectric Relaxation, Electric Conductivity and Thermodynamic Studies on Epoxy Polyurethane Blend and Their Composites","authors":"Elsammani Ali Shokralla","doi":"10.11648/ijmsa.20241301.12","DOIUrl":"https://doi.org/10.11648/ijmsa.20241301.12","url":null,"abstract":"","PeriodicalId":14116,"journal":{"name":"International Journal of Materials Science and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139881150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.11648/ijmsa.20241301.12
Elsammani Ali Shokralla
{"title":"Dielectric Relaxation, Electric Conductivity and Thermodynamic Studies on Epoxy Polyurethane Blend and Their Composites","authors":"Elsammani Ali Shokralla","doi":"10.11648/ijmsa.20241301.12","DOIUrl":"https://doi.org/10.11648/ijmsa.20241301.12","url":null,"abstract":"","PeriodicalId":14116,"journal":{"name":"International Journal of Materials Science and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139821398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-18DOI: 10.11648/j.ijmsa.20241301.11
Mahamat Adoum Abdraman, Idriss Mahamat Yaya, Mahamat Nour Abdallah, Mahamat Hassane Daoud, Mahamat Kher Nediguina, A. M. Tahir, Ruben Mouangue
{"title":"Geotechnical Study and Mechanical Characterization of Two Djarmaya Soils in Chad","authors":"Mahamat Adoum Abdraman, Idriss Mahamat Yaya, Mahamat Nour Abdallah, Mahamat Hassane Daoud, Mahamat Kher Nediguina, A. M. Tahir, Ruben Mouangue","doi":"10.11648/j.ijmsa.20241301.11","DOIUrl":"https://doi.org/10.11648/j.ijmsa.20241301.11","url":null,"abstract":"","PeriodicalId":14116,"journal":{"name":"International Journal of Materials Science and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139615211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-14DOI: 10.11648/j.ijmsa.20231206.11
Muhammad Haseeb-U-Rehman, Naseeb Ahmad, Muhammad Abbas, Abbas Ayoub
{"title":"Study the Physical Properties of Zinc-Copper-Iron Alloy Coating the Mild Steel Substrate at Various Iron Content for Automobile Applications","authors":"Muhammad Haseeb-U-Rehman, Naseeb Ahmad, Muhammad Abbas, Abbas Ayoub","doi":"10.11648/j.ijmsa.20231206.11","DOIUrl":"https://doi.org/10.11648/j.ijmsa.20231206.11","url":null,"abstract":"","PeriodicalId":14116,"journal":{"name":"International Journal of Materials Science and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138971230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research & Application of the Cracking Resistance Test Method of Base-Coat & Render","authors":"Yinxiang Zhang, Zhaojia Wang, Xiangjuan Chen, Tianyong Huang","doi":"10.11648/j.ijmsa.20231205.13","DOIUrl":"https://doi.org/10.11648/j.ijmsa.20231205.13","url":null,"abstract":"","PeriodicalId":14116,"journal":{"name":"International Journal of Materials Science and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139312118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study of the Effect of Gallium Replacement by Thallium in CuGa&lt;sub&gt;(1-x)&lt;/sub&gt;Tl&lt;sub&gt;x&lt;/sub&gt;S&lt;sub&gt;2&lt;/sub&gt; Structure by First-Principles Calculations on CASTEP","authors":"Sangare Kassoum, Diomande Sékou, Bede Affoué Lucie","doi":"10.11648/j.ijmsa.20231205.12","DOIUrl":"https://doi.org/10.11648/j.ijmsa.20231205.12","url":null,"abstract":"","PeriodicalId":14116,"journal":{"name":"International Journal of Materials Science and Applications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135805940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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