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Overview: Versatility of curcumin in management of diabetic retinopathy 概述:姜黄素在糖尿病视网膜病变治疗中的多功能性
Pub Date : 2023-09-15 DOI: 10.18231/j.ijpca.2023.026
Amit Kakad, Layba Sayyad, Hemant Raut, Savita Jagtap, Amruta Sonawane, M.R.N Shaikh, Atul Bendale
On a worldwide scale, the diabetic retinopathy (DR) is listing the primary causes of the loss of sight in the individuals. The main reason behind the occurrence of DR is diabetes mellitus (DM) and diabetic macular edema (DME). Diabetic retinopathy have some types of it i.e Non- proliferative diabetic retinopathy (NPDR) and Proliferative diabetic retinopathy (PDR). Where NPDR is an initial stage and PDR is the severe stage where the person loss the eye sight due to various factors which causes changes in the retinal micro vascularisation. Use of Curcumin in Diabetic Retinopathy may help as a treatment and preventive action for all the stages of DR with its active constituent in various ways. We are focusing on some highlights of curcumin as an active drug to prevent and management of the DR. As the given review presenting the versatility of natural source of medicine like a curcumin can be the best choice of drug for diabetic retinopathy due to its various effects like protect the loss of retinal ganglionic cells, neuroprotective effect by inhibiting oxidative damage to microglia, also act as anti- inflammatory agent, anti VEGF agent, a recognized PPAR-gamma agonist. Hence, In future Curcumin can be preferably useful for management of all the stages involved in Diabetic Retinopathy.
在世界范围内,糖尿病视网膜病变(DR)是个体失明的主要原因。DR发生的主要原因是糖尿病(DM)和糖尿病性黄斑水肿(DME)。糖尿病视网膜病变分为非增生性糖尿病视网膜病变(NPDR)和增生性糖尿病视网膜病变(PDR)。NPDR是初始阶段PDR是严重阶段患者因各种因素导致视网膜微血管改变而丧失视力。在糖尿病视网膜病变中使用姜黄素可以帮助治疗和预防DR的所有阶段,其活性成分以各种方式。我们将重点介绍姜黄素作为预防和治疗糖尿病视网膜病变的活性药物的一些亮点,正如所给的综述所展示的天然药物的多功能性,姜黄素可以成为糖尿病视网膜病变的最佳药物选择,因为它具有多种作用,如保护视网膜神经节细胞的损失,通过抑制小胶质细胞的氧化损伤起到神经保护作用,也可作为抗炎剂,抗VEGF剂,公认的ppar - γ激动剂。因此,在未来,姜黄素可以更好地用于糖尿病视网膜病变的所有阶段的管理。
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引用次数: 0
Intellectual property rights (IPR): An overview 知识产权(IPR):概述
Pub Date : 2023-09-15 DOI: 10.18231/j.ijpca.2023.028
Firoj A Tamboli, Manasi S. Zade, Apurva A. Salunkhe, Monali D. Kore, Amruta D. More, Yash R. Ghadge
Ideas, advancements, and inventiveness that are based on the public's desire to provide the status of the property are all regarded to be subject to intellectual property rights (IPR). This includes works of creativity, literature, and innovations, and it also includes trade names, symbols, and various other characteristics. Intellectual property rights, like other kinds of property rights, exist. They allow owners of patents, trademarks, and works protected by copyright to profit from their own labor or investment in a creation. Intellectual property rights safeguard mental works such as innovations, literary or artistic creations, images, symbols, and furthermore. Intellectual property laws ensure that you profit from what you have created regardless of whether you develop a product, write a book, or discover an innovative medication. Intellectual property protection may take several forms, including trademark rights, copyright, and patent.Intellectual property is required for better identification, planning, marketing, and safeguarding of inventions or creative works. Every industry should have its own IPR rules, manner of leadership, plans, and so on, according to its field of specialization. These rights are outlined in Article 27 of the Universal Declaration of Human Rights, which declares that everyone has the right to profit from the preservation of their moral and financial interests as an outcome of the development of scientific, literary, or artistic work. The phrase "intellectual property" first appeared in the nineteenth century, but it was not broadly acknowledged in the majority of the world's legal systems until the late twentieth century. It is a certification and standard authority for product accreditation and identification in a large market.
基于公众提供财产状态的愿望的想法、进步和创造性都被认为是知识产权(IPR)的对象。这包括创意作品、文学作品和创新作品,还包括商品名称、符号和各种其他特征。知识产权和其他类型的产权一样,是存在的。它们允许专利、商标和受版权保护的作品的所有者从他们自己的劳动或投资中获利。知识产权保护创新成果、文学艺术创作、形象、符号等智力作品。知识产权法确保你从你的创造中获利,无论你是开发了一种产品,写了一本书,还是发现了一种创新药物。知识产权保护可以采取多种形式,包括商标权、版权和专利权。为了更好地识别、规划、营销和保护发明或创造性作品,需要知识产权。每个行业都应该根据其专业领域有自己的知识产权规则、领导方式、计划等。《世界人权宣言》第27条概述了这些权利,该宣言宣布,作为科学、文学或艺术作品发展的结果,人人有权从维护其道德和经济利益中获利。“知识产权”一词最早出现在19世纪,但直到20世纪末才得到世界上大多数法律体系的广泛承认。是一个大市场上产品认可和鉴定的认证和标准权威机构。
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引用次数: 0
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International Journal of Pharmaceutical Chemistry and Analysis
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