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Mercury and lead toxicity induced alterations in the lipid metabolism of heterometrousfulvipes: a study through direct exposure 汞和铅中毒诱导异烟柳脂质代谢的改变:一项通过直接接触的研究
Pub Date : 2017-05-28 DOI: 10.24327/ijrsr.2017.0805.0317
M. Rao, Y. Acharya, S. JitenderKumarNaik, S. Bala, Samir Fatteh, Simi Paramban, Amin Fateh
Heavy metal exposure in animals can lead to profound effect on growth, development and biochemical constituents. It is necessary that the heavy metal toxicity be well documented and adequate precaution should be taken in mother and fetus to decrease its detrimental effects. An experimental study was performed with viviparous animal Heterometrousfulvipes to access the cumulative effect of chronic heavy metals exposure on lipid metabolism.Chronic heavy metal exposure resulted in decrease in biochemical constituents of lipids, with decrease in hepatopancreatic weight, hepato -somatic index and embryonic length and weight.
重金属对动物生长发育和生物化学成分的影响是深远的。有必要对重金属毒性进行充分的记录,并对母亲和胎儿采取适当的预防措施,以减少其有害影响。本研究以胎生动物异长尾猴为研究对象,探讨慢性重金属暴露对动物脂质代谢的累积效应。慢性重金属暴露导致肝脏脂质生化成分降低,肝胰重、肝体指数、胚胎长度和重量下降。
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引用次数: 0
DESIGN AND EVALUATION OF HYDRALAZINE HYDROCHLORIDE MOUTH DISSOLVING TABLET FOR THE MANAGEMENT OF HYPERTENSION 盐酸肼嗪口腔溶片治疗高血压的设计与评价
Pub Date : 2017-05-28 DOI: 10.24327/ijrsr.2017.0805.0310
S. Muthukumar, R. Sundaraganapathy
Eclampsia and preeclampsia is an acute and life threatening complication during pregnancy.Hydralazine hydrochloride is one of the drugs of choice in treating this condition The purpose of the present research work was to formulate the orodispersible tablets by using different methods and provide a suitable patient convenience dosage form to enhance the bioavailability and provide quick onset of action. Formulation of orodispersible tablets of Hydralazine hydrochloride were prepared by using various superdisintegrants like crosspovidone, cross caramellose sodium and sodium starch glycolate by direct compression method and camphor as an excipient by sublimation technique. The formulas were evaluated for compatibility and Precompressional studies. The formulations were evaluated for weight variation, thickness, hardness, friability, content uniformity, disintegration time, wetting time, water absorption ratio and release profile. Among all the formulations F9 and SF9 showed effective percentage of drug release at 12 minutes indicating faster and maximum absorption at the site of administration.
子痫和先兆子痫是一种急性和危及生命的并发症在怀孕期间。盐酸海达拉嗪是治疗此病的首选药物之一,本研究的目的是通过不同的方法制备口服分散片,并提供适合患者的方便剂型,以提高生物利用度和快速起效。以交叉聚维酮、交叉焦糖钠、乙醇酸淀粉钠等多种超崩解剂为原料,采用直接压缩法,以樟脑为辅料,升华法制备盐酸羟丙嗪口腔分散片。评估了配方的相容性和预压缩研究。对配方的重量变化、厚度、硬度、脆性、含量均匀性、崩解时间、润湿时间、吸水率和释放度进行了评价。其中F9和SF9在12分钟的有效释药率表明给药部位吸收更快,吸收最大。
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引用次数: 1
Temporal characteristics of aerosol physical properties at visakhapatnam on the east coast of india 印度东海岸维沙卡帕特南气溶胶物理特性的时间特征
Pub Date : 2017-05-28 DOI: 10.24327/ijrsr.2017.0805.0235
S. Rao
An extensive, multi institutional, multi instrumental and multi-platform field experiment ‘Integrated Campaign Aerosols, gases and Radiation Budget (ICARB) was carried out. The objective this Campaign ever conducted in the Indian region was to characterize the physico-chemical properties and radiative effects of the aerosols and trace gases over the Indian landmass and the adjoining oceanic regions of the Arabian Sea, Northern Indian Ocean, and Bay of Bengal. The temporal variations of aerosol optical depth, near surface aerosol mass size distributions and BC mass concentrations show significantly higher aerosol optical depth and near surface mass concentrations during the first and last weeks of April 2007. The mean BC mass fraction in the fine mode aerosol was around of 11 %. A comparison of the temporal variation of the Aerosol properties at Visakhapatnam with the MODIS derived aerosol optical depth along the cruise locations indicate a significant coincidence suggesting that the aerosol transport from the eastern coastal regions of the peninsular India plays an important role on the observed spatial variation in the aerosol optical depths over the near coastal oceanic regions of Bay of Bengal.
开展了一项广泛的、多机构、多仪器和多平台的现场试验“综合战役气溶胶、气体和辐射预算”(ICARB)。在印度地区开展的这一运动的目的是描述气溶胶和微量气体在印度大陆及其毗邻的阿拉伯海、北印度洋和孟加拉湾海洋地区的物理化学性质和辐射效应。气溶胶光学深度、近地表气溶胶质量大小分布和BC质量浓度的时间变化表明,在2007年4月的前一周和最后一周,气溶胶光学深度和近地表质量浓度显著升高。细态气溶胶中BC的平均质量分数约为11%。维萨卡帕特南气溶胶特性的时间变化与MODIS反演的沿巡航地点气溶胶光学深度的时间变化的比较表明,两者具有显著的一致性,表明来自印度半岛东部沿海地区的气溶胶输送对孟加拉湾近沿海海洋地区观测到的气溶胶光学深度的空间变化起重要作用。
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引用次数: 0
Prevalence of anatomical variations of osteomeatal complex and its correlation with incidental maxillary sinus pathologies using cone-beam computed tomography: an observational study 使用锥形束计算机断层扫描发现骨突复合体解剖变异的普遍性及其与偶然上颌窦病变的相关性:一项观察性研究
Pub Date : 2017-05-28 DOI: 10.24327/ijrsr.2017.0805.0315
Daya K. Jangam, Namrata P Lohakpure, Dipika D Gavit, A. Patil
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引用次数: 1
Immediate fever after clean operations (class i of altemeier) in the northeast of the democratic republic of thecongo (drc): etiologic and therapeutic aspects 刚果民主共和国东北部洁净手术后立即发热(阿尔特迈尔病第一类):病因和治疗方面
Pub Date : 2017-05-28 DOI: 10.24327/ijrsr.2017.0805.0224
Maoneo Azabali, TalonaLehumadja, Awikoko Mutupeni, Mukulutaghe Pierre, A. Longombe
Background: A high temperature compared to normal in postoperative first forty-eight hours or immediate postoperative fever is commonly observed and raises anxiety both in the patient than in the caregiver himself. This last is still in trouble whether the fever is related or no to infection especially when the operation is clean. This study aims to determine association between the immediate postoperative fever and infection after clean operations (Class I of Althemeir) in order to limit the misuse of antibiotics and antimalarials. Patients and Methods: This is a prospective study led at the Referral General Hospital of Kabondo, in the city of Kisangani to north-eastern of Democratic Republic of Congo, with 209 operated. Data were recorded on Excel spreadsheet and analyzed with SPSS 20 software. Results: In the immediate postoperative period, 29 (13.87%) operated presented fever. 51.72% of these fevers were moderate around 38°C to 39°C. Caesareans predominated (48.27%). The systemic inflammatory syndrome was found in 55.17% of the cases followed of the malaria in 41.38% of which 37.93% with the positive thick drop. All operated were under a post-operative systematic antibiotherapy (100%) and 55.17% of operated received association antibiotics, antipyretics and antimalarials. Conclusion: Most of immediate post-operative fever after a clean operation is not infectious although malaria remains as significant cause in countries with malaria endemicity.
背景:术后48小时内体温高于正常值或术后立即发热是常见的,这引起了患者和护理者自身的焦虑。无论发烧是否与感染有关,尤其是在手术清洁的情况下,最后一点仍然是麻烦的。本研究旨在确定清洁手术(Althemeir第一类)后立即术后发热与感染之间的关系,以限制抗生素和抗疟药的滥用。患者和方法:这是在刚果民主共和国东北部基桑加尼市Kabondo转诊总医院领导的一项前瞻性研究,对209例患者进行了手术。数据用Excel表格记录,用SPSS 20软件分析。结果:术后即刻发热29例(13.87%)。51.72%为中度发热,在38°C至39°C之间。剖腹产占多数(48.27%)。55.17%的病例出现全身性炎症综合征,41.38%的病例出现全身性炎症综合征,其中37.93%的病例出现厚滴阳性。所有患者术后均接受系统抗生素治疗(100%),55.17%的患者接受联合抗生素、解热药和抗疟药治疗。结论:尽管疟疾在疟疾流行国家仍是主要原因,但清洁手术后立即发热多数不具有传染性。
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引用次数: 0
Qualitative phytochemical analysis of some leafy vegetables used to cure anemia in west singhbhum, jharkhand, india 印度贾坎德邦西辛格邦一些治疗贫血的叶类蔬菜的定性植物化学分析
Pub Date : 2017-05-28 DOI: 10.24327/ijrsr.2017.0805.0290
Dolly Tudu, Vishnu Shankar Sinha
Present study reports the preliminary qualitative phytochemical analysis of six medicinal plants viz. Amaranthus tricolor L. (Amaranthaceae), Centella asiatica L.(Apiaceae), Chenopodium album L.(Amaranthaceae), Cicer arietinum L.(Fabaceae), Colocasia esculentum L.(Araceae) and Ipomia aquatic L. (Convolvulaceae). The qualitative phytochemical analysis was carried out after extracting sample using soxhlet extraction by using double distilled water, ethanol and methanol as extractants. Various tests were carried out for the detection of phytochemicals such as Alkaloids, Flavonoids, Saponins, Phenols, Carbohydrates, Tannins, Protein and Glycosides in the plant extracts and iron spot was tested by 5% potassium thyocinate solution (KSCN). Our result confirmed the presence of major classes of photochemical and iron in the plant leaves extracts. This preliminary study draws attention to the need for further studies to know the exact active secondary metabolites which is responsible for the treatment of Anemia and other diseases.
本文报道了苋菜科、雪草科、藜草科、茜草科、天南星科、秋葵科、水草科等6种药用植物的植物化学初步定性分析。采用索氏提取法,以双蒸馏水、乙醇和甲醇为萃取剂提取样品,对样品进行定性植物化学分析。对植物提取物中的生物碱、黄酮类、皂苷、酚类、碳水化合物、单宁、蛋白质和苷类等植物化学物质进行了多种检测,并采用5%胸腺酸钾溶液(KSCN)进行了铁斑检测。我们的结果证实了植物叶片提取物中存在主要类别的光化学和铁。这一初步研究引起了人们的注意,需要进一步研究以了解治疗贫血和其他疾病的确切活性次级代谢物。
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引用次数: 0
Antifungal activity of eucalyptus oil against clinical isolates of candida species 桉树油对念珠菌临床分离株的抑菌活性研究
Pub Date : 2017-05-28 DOI: 10.24327/ijrsr.2017.0805.0297
A. Deepak, P. Gopinath
The majority of mycotic infections are due to Candida species, out of which Candida albicans is being the most frequently isolated species. Eucalyptus is one of the very important and most widely planted genera across the world. It is a tall, evergreen tree, native to Australia and Tasmania, successfully introduced worldwide, now extensively planted in many other countries. Thus, the aim of the present study was to determine the antifungal activity of eucalyptus oil against clinical isolates of Candida spp. We have observed that, clinical isolates of Candida species were not inhibited in any of these dilutions of this oil. The eucalyptus oil does not have antifungal activity against Candida species. However, it is important to include more number of isolates and different dilutions to validate the results.
大多数真菌感染是由念珠菌引起的,其中白色念珠菌是最常见的分离种。桉树是世界上最重要和最广泛种植的属之一。它是一种高大的常青树,原产于澳大利亚和塔斯马尼亚,成功地引进世界各地,现在在许多其他国家广泛种植。因此,本研究的目的是确定桉树油对假丝酵母菌临床分离株的抗真菌活性。我们已经观察到,临床分离株假丝酵母菌在任何稀释度的桉树油中都没有被抑制。桉树油对念珠菌没有抗真菌活性。然而,重要的是要包括更多的分离株和不同的稀释度来验证结果。
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引用次数: 2
Preliminary characterization and invitro cytotoxicic studies of the polysaccharide from araucaria heterophylla 龙柏多糖的初步鉴定及体外细胞毒性研究
Pub Date : 2017-05-28 DOI: 10.24327/ijrsr.2017.0805.0303
R. Gayathri, R. Sundaraganapathy
{"title":"Preliminary characterization and invitro cytotoxicic studies of the polysaccharide from araucaria heterophylla","authors":"R. Gayathri, R. Sundaraganapathy","doi":"10.24327/ijrsr.2017.0805.0303","DOIUrl":"https://doi.org/10.24327/ijrsr.2017.0805.0303","url":null,"abstract":"","PeriodicalId":14198,"journal":{"name":"International journal of recent scientific research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91264080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Analysis of technology in disaster management in india 印度灾害管理技术分析
Pub Date : 2017-05-28 DOI: 10.24327/ijrsr.2017.0805.0260
N. Sharma
Every passing year is marked with one or more catastrophic disaster in world. Natural disasters results in adverse consequences as loss of life, property and economic disruptions. India is vulnerable, in varying degrees, to a large number of disasters. To manage such crisis situation during disasters, there is requirement of dissemination of timely information and knowledge. New emerging technologies are important tool to deal with such situations. This paper analyze role of Geological Information System (GIS) in disaster management. Increased usage of such technology can be effective in disaster management.
世界上每年都会发生一场或多场灾难性的灾难。自然灾害造成生命、财产损失和经济中断等不利后果。印度在不同程度上容易受到大量灾害的影响。为了在灾害中管理这种危机情况,需要及时传播信息和知识。新兴技术是应对这种情况的重要工具。本文分析了地质信息系统(GIS)在灾害管理中的作用。增加使用这种技术可以有效地进行灾害管理。
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引用次数: 0
A comparative evaluation of fracture resistance of endodontically treated teeth restored with three different post and core systems and two different luting agents – an invitro study 三种不同的桩核系统和两种不同的修复剂对根管治疗后的牙齿的抗折性的比较研究
Pub Date : 2017-05-28 DOI: 10.24327/IJRSR.2017.0805.0279
Neena Chandran, Noushad M C, Bijith Balan
Purpose: To compare fracture resistance and primary mode of failure of endodontically treated teeth with three different posts systems and two variant luting agents. Materials and Methods: Root canal treatment was performed on 40 maxillary incisors and samples were divided into 4 groups. For three experimental groups post space preparation was done and teeth were restored with cast post-core (Group B), prefabricated glass fibre post (everStick post) with composite core (Group C) and prefabricated zirconia posts with composite core (Group D). Control group (A) samples were selected with intact coronal structure. Post space was prepared in all samples. Two type of luting cements dual cure resin cement (Luxacore Z) and glass ionomer cement (Fuji I, GC) were used for post cementation. The core was standardized to 4mm × 5mm. Prepared samples were subjected to compressive load of 0.5mm/min at 135o angulation. The load at which fracture occurred and fracture mode were analysed statistically by one way ANOVA, post-hoc tukey test and chi-square test. Results: The findings showed statistically significant difference between failure loads. The mean load required to fracture glass fibre was highest (711MPa) and least for control group (231MPa). The glass fibre posts and zirconia posts showed favorable fracture. Conclusion: The results concluded that endodontically treated teeth without post core system showed least fracture resistance signifying need to reinforce tooth. Use of glass fibre post (everStick post) showed highest mean fracture resistance regardless of luting agent.
目的:比较三种不同桩位系统和两种不同植牙剂对根管治疗牙的抗折性和主要失效模式。材料与方法:对40个上颌切牙进行根管治疗,分为4组。三个实验组分别采用铸造桩核(B组)、预制玻璃纤维桩(everStick桩)复合桩核(C组)和预制氧化锆桩复合桩核(D组)进行桩位准备和牙体修复。对照组(A组)冠状结构完整。在所有样品中都准备了Post space。采用双固化树脂水泥(Luxacore Z)和玻璃离子水泥(Fuji I, GC)两种类型的水泥进行后固井。芯被标准化为4mm × 5mm。制备的样品在1350角方向承受0.5mm/min的压缩载荷。采用单因素方差分析、事后检验和卡方检验对断裂发生载荷和断裂方式进行统计学分析。结果:失效载荷之间的差异有统计学意义。断裂玻璃纤维所需的平均载荷最大(711MPa),对照组最小(231MPa)。玻璃纤维桩和氧化锆桩均表现出良好的断裂。结论:无桩核系统根管治疗后的牙体抗折断能力最小,提示需要进行牙体加固。使用玻璃纤维桩(everStick桩),无论使用何种粘结剂,其平均抗断裂能力最高。
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引用次数: 0
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International journal of recent scientific research
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