Pub Date : 2023-09-08DOI: 10.18203/issn.2455-4529.intjresdermatol20232835
Pradeep Kumari, Deepa K. Bhatt, K. Manoharan, Praveen Agarwal, B. Leelavathy, Anurag Arya, Rathish Nair, Krishnaprasad Korukonda
Background: Face cleansers are recommended as adjuncts to acne therapy to counteract the acne related manifestation like acne spots and post inflammatory hyperpigmentation (PIH). This complementary study was designed to assess the clinical impact and tolerability of glycolic acid, aloe vera and vitamin-E based face cleanser for daily use in acne patients prescribed with clindamycin, tretinoin, adapalene and benzoyl peroxide for management of acne in real-world scenario. Methods: We conducted a retrospective review at 193 centres, focusing on individuals having acne with oily and mix skin types who used face cleanser twice a day. Total 619 cases (D age: 28.94±7.92 years) of acne were further analysed over a 4-week study period to study improvement in post-inflammatory hyperpigmentation, acne spot reduction and enhance skin radiance and glow using subjective assessment questionnaires. Results: The face cleanser, when used regularly with standard of care, significantly reduced acne (43.58%), acne spots (44.85%), and PIH (46.06%) with statistical significance (p<0.01). Patients with oily and mix skin type, 337 (54.44%) and 264 (42.65%) rated improvement on acne spots, PIH, radiance, and glow to be good to excellent, respectively. No patients experienced serious adverse events (AEs) or cleanser-related adverse event. Conclusions: The facial cleanser demonstrated effectiveness and tolerance in treating acne patients who were prescribed with anti-bacterial and anti-inflammatory agents. In 4-week long treatment period, the facial cleanser enhanced skin radiance and also demonstrated its worth as a beneficial inclusion in everyday skincare regimens.
{"title":"Exploring clinical effects and usage patterns of a daily face cleanser enriched with glycolic acid, aloe vera, and vitamin-E for acne management: a post-hoc analysis","authors":"Pradeep Kumari, Deepa K. Bhatt, K. Manoharan, Praveen Agarwal, B. Leelavathy, Anurag Arya, Rathish Nair, Krishnaprasad Korukonda","doi":"10.18203/issn.2455-4529.intjresdermatol20232835","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20232835","url":null,"abstract":"Background: Face cleansers are recommended as adjuncts to acne therapy to counteract the acne related manifestation like acne spots and post inflammatory hyperpigmentation (PIH). This complementary study was designed to assess the clinical impact and tolerability of glycolic acid, aloe vera and vitamin-E based face cleanser for daily use in acne patients prescribed with clindamycin, tretinoin, adapalene and benzoyl peroxide for management of acne in real-world scenario. Methods: We conducted a retrospective review at 193 centres, focusing on individuals having acne with oily and mix skin types who used face cleanser twice a day. Total 619 cases (D age: 28.94±7.92 years) of acne were further analysed over a 4-week study period to study improvement in post-inflammatory hyperpigmentation, acne spot reduction and enhance skin radiance and glow using subjective assessment questionnaires. Results: The face cleanser, when used regularly with standard of care, significantly reduced acne (43.58%), acne spots (44.85%), and PIH (46.06%) with statistical significance (p<0.01). Patients with oily and mix skin type, 337 (54.44%) and 264 (42.65%) rated improvement on acne spots, PIH, radiance, and glow to be good to excellent, respectively. No patients experienced serious adverse events (AEs) or cleanser-related adverse event. Conclusions: The facial cleanser demonstrated effectiveness and tolerance in treating acne patients who were prescribed with anti-bacterial and anti-inflammatory agents. In 4-week long treatment period, the facial cleanser enhanced skin radiance and also demonstrated its worth as a beneficial inclusion in everyday skincare regimens.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136298774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-24DOI: 10.18203/issn.2455-4529.intjresdermatol20232551
Dhruv Gupta, P. Agarwal, Raju G. Chaudhary, Kalgi D. Baxi
Panniculitis refers to the inflammation of the subcutaneous fat. Subacute nodular migratory panniculitis (Aka Vilanova disease) is a rare type of panniculitis seen predominantly in women. Clinically, it closely resembles erythema nodosum but is often unilateral as opposed to the bilateral involvement in erythema nodosum. Triggering factors include infections, drugs, thyroid disorders, pregnancy, or malignancies. We report a rare case of a 52-year-old female who was a known case of hypothyroidism and presented with sudden onset of red colored painful lesions with raised temperature over both lower limbs. Hematological evaluation was unremarkable except for raised erythrocyte sedimentation rate. Histopathological examination of the lesion showed septal panniculitis with giant cells, suggestive of subacute nodular migratory panniculitis. The patient responded very well to treatment with capsule indomethacin.
{"title":"Subacute nodular migratory panniculitis, a rare presentation of a rare disease: a case report","authors":"Dhruv Gupta, P. Agarwal, Raju G. Chaudhary, Kalgi D. Baxi","doi":"10.18203/issn.2455-4529.intjresdermatol20232551","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20232551","url":null,"abstract":"Panniculitis refers to the inflammation of the subcutaneous fat. Subacute nodular migratory panniculitis (Aka Vilanova disease) is a rare type of panniculitis seen predominantly in women. Clinically, it closely resembles erythema nodosum but is often unilateral as opposed to the bilateral involvement in erythema nodosum. Triggering factors include infections, drugs, thyroid disorders, pregnancy, or malignancies. We report a rare case of a 52-year-old female who was a known case of hypothyroidism and presented with sudden onset of red colored painful lesions with raised temperature over both lower limbs. Hematological evaluation was unremarkable except for raised erythrocyte sedimentation rate. Histopathological examination of the lesion showed septal panniculitis with giant cells, suggestive of subacute nodular migratory panniculitis. The patient responded very well to treatment with capsule indomethacin.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80305709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-24DOI: 10.18203/issn.2455-4529.intjresdermatol20232550
Amarthya S. Racha, P. Ashwani, Polevoina Swarnalatha
Cutaneous adverse drug reactions vary in severity, from mild erythematous skin lesions to life-threatening toxic epidermal necrolysis. Antiepileptics, antipsychotics, antimicrobials, and diuretics are associated with these adverse reactions. We report a case of cefditoren pivoxil-induced toxic epidermal necrolysis in a 46-year-old Indian woman who presented initially with a maculopapular rash that eventually progressed to steroid-refractory toxic epidermal necrolysis. The patient succumbed to her illness on day 33 of the index rash following septic shock.
{"title":"Cefditoren pivoxil induced toxic epidermal necrolysis: a case report","authors":"Amarthya S. Racha, P. Ashwani, Polevoina Swarnalatha","doi":"10.18203/issn.2455-4529.intjresdermatol20232550","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20232550","url":null,"abstract":"Cutaneous adverse drug reactions vary in severity, from mild erythematous skin lesions to life-threatening toxic epidermal necrolysis. Antiepileptics, antipsychotics, antimicrobials, and diuretics are associated with these adverse reactions. We report a case of cefditoren pivoxil-induced toxic epidermal necrolysis in a 46-year-old Indian woman who presented initially with a maculopapular rash that eventually progressed to steroid-refractory toxic epidermal necrolysis. The patient succumbed to her illness on day 33 of the index rash following septic shock.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76458694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-24DOI: 10.18203/issn.2455-4529.intjresdermatol20232547
Diana M. Ibarra Tostado, Alejandra Romero Parra, Marisol Padilla Ramirez, Sharira M. Lopez Lopez, Diana L. Macias Cedeño, Cinthya P. Reyes Enriquez, Maria J. Zorrilla Marina, J. M. Zepeda Torres
Bullous systemic lupus erythematosus (BSLE) is a rare blistering eruption that can occur in patients with systemic lupus erythematosus. Although 59 to 85% of patients will have skin manifestations, less than 5% will develop the bullous disease, which is even rarer (1%) in the pediatric population. We present the case of a 16-year-old female patient in whom a diagnosis of BSLE was made through clinical presentation, histological study by biopsy, and direct immunofluorescence. Due to the low incidence of cases reported in pediatric patients, it is possible that the diagnosis may not be made immediately, which is why we emphasize the importance of obtaining an accurate diagnosis and providing timely treatment.
{"title":"Clinical presentation of bullous systemic lupus erythematosus in a pediatric patient: a case report","authors":"Diana M. Ibarra Tostado, Alejandra Romero Parra, Marisol Padilla Ramirez, Sharira M. Lopez Lopez, Diana L. Macias Cedeño, Cinthya P. Reyes Enriquez, Maria J. Zorrilla Marina, J. M. Zepeda Torres","doi":"10.18203/issn.2455-4529.intjresdermatol20232547","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20232547","url":null,"abstract":"Bullous systemic lupus erythematosus (BSLE) is a rare blistering eruption that can occur in patients with systemic lupus erythematosus. Although 59 to 85% of patients will have skin manifestations, less than 5% will develop the bullous disease, which is even rarer (1%) in the pediatric population. We present the case of a 16-year-old female patient in whom a diagnosis of BSLE was made through clinical presentation, histological study by biopsy, and direct immunofluorescence. Due to the low incidence of cases reported in pediatric patients, it is possible that the diagnosis may not be made immediately, which is why we emphasize the importance of obtaining an accurate diagnosis and providing timely treatment.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82912097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-24DOI: 10.18203/issn.2455-4529.intjresdermatol20232546
Edith Dariela Riojas-Hernández, S. Chávez-Álvarez
Eosinophilic fasciitis is a rare condition characterized by edema, induration, thickening of the skin and soft tissues, hypergammaglobulinemia and peripheral eosinophilia. We present two patients with eosinophilic fasciitis and no elevation of eosinophils at the time of diagnosis.
{"title":"Eosinophilic fasciitis with elevated inflammatory markers: another clue","authors":"Edith Dariela Riojas-Hernández, S. Chávez-Álvarez","doi":"10.18203/issn.2455-4529.intjresdermatol20232546","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20232546","url":null,"abstract":"Eosinophilic fasciitis is a rare condition characterized by edema, induration, thickening of the skin and soft tissues, hypergammaglobulinemia and peripheral eosinophilia. We present two patients with eosinophilic fasciitis and no elevation of eosinophils at the time of diagnosis.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89583976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-24DOI: 10.18203/issn.2455-4529.intjresdermatol20232536
D. Shankar, Rajat Kandhari, Sanskriti Varma, V. Mallela, R. Dixit, Rickson R Pereira
Background: Hyperpigmentation is the third most common dermatological disorder and has major psychosocial impairment. It comes in a variety of forms. The most well-known are age spots, freckles, melasma and post-inflammatory hyperpigmentation. Hyperpigmentation in friction-prone areas (armpits, inner thighs, elbows, knees, groin, etc.) has a significant impact on affected individuals. Unfortunately, there are currently no well-tolerated options available that are intended particularly for these sensitive areas. Methods: Dermatologists across India were provided a questionnaire consisting of questions related to number of the patients seen with hyperpigmentation in intimate & high friction areas every week and their clinical experience regarding the use of Pigmentbio Sensitive areas containing active ingredients (Andrographolide+Glabridin+Lysine azelate+Laminaria ochroleuca extract). The results were analyzed using a visual analogue scale. Results: The study included a total of 1402 patients, and 75 dermatologists provided complete responses. The majority (96%) of the dermatologists recommended Pigmentbio Sensitive areas for intimate & high friction areas. These dermatologists also rated tolerability and safety of Pigmentbio Sensitive areas as "excellent" to "good" based on various criteria. These included tolerability after waxing and shaving the bikini line, soothing effect after mechanical erythema from taking off tight clothing, hydrating power when compared to other products, cosmetic acceptability for frictional and intimate areas, and safety on intimate areas. Conclusions: This study findings indicated that Pigmentbio Sensitive areas is a preferred formulation by dermatologists across India for the management of hyperpigmentation in intimate & high friction areas with proven tolerability and safety.
{"title":"A multicentric, prospective, observational study evaluating the practice pattern and use of fixed dose topical regimen for hyperpigmentation in intimate and high friction areas","authors":"D. Shankar, Rajat Kandhari, Sanskriti Varma, V. Mallela, R. Dixit, Rickson R Pereira","doi":"10.18203/issn.2455-4529.intjresdermatol20232536","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20232536","url":null,"abstract":"Background: Hyperpigmentation is the third most common dermatological disorder and has major psychosocial impairment. It comes in a variety of forms. The most well-known are age spots, freckles, melasma and post-inflammatory hyperpigmentation. Hyperpigmentation in friction-prone areas (armpits, inner thighs, elbows, knees, groin, etc.) has a significant impact on affected individuals. Unfortunately, there are currently no well-tolerated options available that are intended particularly for these sensitive areas.\u0000Methods: Dermatologists across India were provided a questionnaire consisting of questions related to number of the patients seen with hyperpigmentation in intimate & high friction areas every week and their clinical experience regarding the use of Pigmentbio Sensitive areas containing active ingredients (Andrographolide+Glabridin+Lysine azelate+Laminaria ochroleuca extract). The results were analyzed using a visual analogue scale.\u0000Results: The study included a total of 1402 patients, and 75 dermatologists provided complete responses. The majority (96%) of the dermatologists recommended Pigmentbio Sensitive areas for intimate & high friction areas. These dermatologists also rated tolerability and safety of Pigmentbio Sensitive areas as \"excellent\" to \"good\" based on various criteria. These included tolerability after waxing and shaving the bikini line, soothing effect after mechanical erythema from taking off tight clothing, hydrating power when compared to other products, cosmetic acceptability for frictional and intimate areas, and safety on intimate areas.\u0000Conclusions: This study findings indicated that Pigmentbio Sensitive areas is a preferred formulation by dermatologists across India for the management of hyperpigmentation in intimate & high friction areas with proven tolerability and safety.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87827853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-24DOI: 10.18203/issn.2455-4529.intjresdermatol20232542
Ayesha Sharmeen, S. Amin, M. Adil, Iti Varshney
Background: Dermatophytosis is a common dermatological problem. Recent studies have reported an increase in the prevalence of the disease. Management of dermatophytosis thus has become challenging for both dermatologists and patients due to their resistance to treatment and their refractory nature. Currently the management of dermatophytic infection includes both oral and topical antifungals. The study compared the clinical efficacy and adverse effect profile of systemic with topical drugs. Methods: Patients were randomly divided into two groups of 90 each. They were given oral Itraconazole 100 mg twice daily with Sertaconazole 2 % cream twice daily (Group A) and oral Terbinafine 250 mg once daily with Sertaconazole 2 % cream twice daily (Group B) till complete resolution of lesions or a maximum of six weeks. The response was assessed by the improvement in signs and symptoms of each of the clinical parameter, pruritus, erythema, scaling. Results: At week 6, mycological cure was seen in 92.9% in Group A as compared to 86.9% of patients in Group B. There was a significant improvement in percentage change in pruritus, erythema, and scaling in both the groups from 0 to 6 weeks (p-value: <0.0001). Mild adverse effects such as gastrointestinal upset, headache, and raised transaminases were observed which were comparable in both the groups. Conclusions: On comparison of the groups, we observed that both were effective but Itraconazole with Sertaconazole 2% cream was more efficacious in terms of both clinical (pruritus, scaling, and erythema) and mycological cure.
{"title":"Study of effect of oral itraconazole with 2% sertaconazole cream versus oral terbinafine with 2% sertaconazole cream in dermatophytosis","authors":"Ayesha Sharmeen, S. Amin, M. Adil, Iti Varshney","doi":"10.18203/issn.2455-4529.intjresdermatol20232542","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20232542","url":null,"abstract":"Background: Dermatophytosis is a common dermatological problem. Recent studies have reported an increase in the prevalence of the disease. Management of dermatophytosis thus has become challenging for both dermatologists and patients due to their resistance to treatment and their refractory nature. Currently the management of dermatophytic infection includes both oral and topical antifungals. The study compared the clinical efficacy and adverse effect profile of systemic with topical drugs.\u0000Methods: Patients were randomly divided into two groups of 90 each. They were given oral Itraconazole 100 mg twice daily with Sertaconazole 2 % cream twice daily (Group A) and oral Terbinafine 250 mg once daily with Sertaconazole 2 % cream twice daily (Group B) till complete resolution of lesions or a maximum of six weeks. The response was assessed by the improvement in signs and symptoms of each of the clinical parameter, pruritus, erythema, scaling. \u0000Results: At week 6, mycological cure was seen in 92.9% in Group A as compared to 86.9% of patients in Group B. There was a significant improvement in percentage change in pruritus, erythema, and scaling in both the groups from 0 to 6 weeks (p-value: <0.0001). Mild adverse effects such as gastrointestinal upset, headache, and raised transaminases were observed which were comparable in both the groups. \u0000Conclusions: On comparison of the groups, we observed that both were effective but Itraconazole with Sertaconazole 2% cream was more efficacious in terms of both clinical (pruritus, scaling, and erythema) and mycological cure.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"285 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86402785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-24DOI: 10.18203/issn.2455-4529.intjresdermatol20232534
Sunayana Kushwah, C. Namdeo, K. Bhatia
Background: Topical steroid dependent or damaged face is an alarming upcoming entity rampant in India due to over-the-counter availability of topical corticosteroids containing products. The present study aimed to study the clinical and dermoscopic changes in patients with topical steroid damaged face and to correlate them with potency and duration of application of the TCS. Methods: 80 patients visiting the dermatology OPD & IPD at SAIMS Hospital & PG Institute, Indore, with the chief complains of redness, itching, red raised lesions, burning, swelling, photosensitivity, pigmentation; with a history of application of topical corticosteroids of any potency on face for continuous 7 days or intermittent for 15 or more days were enrolled for the study. Results: Mean age of the patients was 31.5±8.13 years. Male to female ratio was 1:9. Twelve (15.2%) patients abused TCS for more than one year. Presenting complains of the patients were redness (82.5%), itching (66.3%), hypertrichosis (47.5%), pigmentation (66.3%), burning (38.8%) and acne (28.8%). The most common dermoscopy findings i.e., unpatterned brown pigmentation (86.3%), polygonal vessels (73.8%), fine scales (52.5%), hypertrichosis (53.8%), follicular plugs (32.5%), micropustules (15%) and ivory patches (11.3%) were observed in a statistically higher proportion of cases dermoscopically Conclusions: Dermoscopy in TSDF can help dermatologists in a multitude of ways from confirming the diagnosis to differentiating from other causes of red face and predicting the approximate duration of TCS abuse.
{"title":"Study of clinicodermoscopic features of topical steroid damaged face patients","authors":"Sunayana Kushwah, C. Namdeo, K. Bhatia","doi":"10.18203/issn.2455-4529.intjresdermatol20232534","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20232534","url":null,"abstract":"\u0000Background: Topical steroid dependent or damaged face is an alarming upcoming entity rampant in India due to over-the-counter availability of topical corticosteroids containing products. The present study aimed to study the clinical and dermoscopic changes in patients with topical steroid damaged face and to correlate them with potency and duration of application of the TCS.\u0000Methods: 80 patients visiting the dermatology OPD & IPD at SAIMS Hospital & PG Institute, Indore, with the chief complains of redness, itching, red raised lesions, burning, swelling, photosensitivity, pigmentation; with a history of application of topical corticosteroids of any potency on face for continuous 7 days or intermittent for 15 or more days were enrolled for the study.\u0000Results: Mean age of the patients was 31.5±8.13 years. Male to female ratio was 1:9. Twelve (15.2%) patients abused TCS for more than one year. Presenting complains of the patients were redness (82.5%), itching (66.3%), hypertrichosis (47.5%), pigmentation (66.3%), burning (38.8%) and acne (28.8%). The most common dermoscopy findings i.e., unpatterned brown pigmentation (86.3%), polygonal vessels (73.8%), fine scales (52.5%), hypertrichosis (53.8%), follicular plugs (32.5%), micropustules (15%) and ivory patches (11.3%) were observed in a statistically higher proportion of cases dermoscopically\u0000Conclusions: Dermoscopy in TSDF can help dermatologists in a multitude of ways from confirming the diagnosis to differentiating from other causes of red face and predicting the approximate duration of TCS abuse.\u0000","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91040818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-24DOI: 10.18203/issn.2455-4529.intjresdermatol20232545
M. N. Amaewhule, E. Amadi, C. Ogbu
Bullous pemphigoid (BP) is a chronic autoimmune bullous eruption that is characterized by pruritic, tense sub-epidermal bullae. It commonly affects those aged 60 years and above. It has no gender predilection. It can be generalized or localized. This is a case report of 2 female patients with localized BP presenting as recurrent skin rash of more than 1 year duration which were later referred to the dermatology clinic. The patients were both females less than 40 years of age who have been having recurrent skin rash that have been associated with intense itching localized to a unilateral lower limb. The first patient had obvious bullae and ulcers while the second didn’t have any obvious bullae. Initial clinical diagnoses did not consider BP. Punch skin biopsy was done in both cases that revealed histologic features confirming BP. Clinicians should have high index of suspicion of BP even in cases of localized chronic wound or recurrent ulcers irrespective of the age of patient.
{"title":"Case report on localized bullous pemphigoid in two young females","authors":"M. N. Amaewhule, E. Amadi, C. Ogbu","doi":"10.18203/issn.2455-4529.intjresdermatol20232545","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20232545","url":null,"abstract":"Bullous pemphigoid (BP) is a chronic autoimmune bullous eruption that is characterized by pruritic, tense sub-epidermal bullae. It commonly affects those aged 60 years and above. It has no gender predilection. It can be generalized or localized. This is a case report of 2 female patients with localized BP presenting as recurrent skin rash of more than 1 year duration which were later referred to the dermatology clinic. The patients were both females less than 40 years of age who have been having recurrent skin rash that have been associated with intense itching localized to a unilateral lower limb. The first patient had obvious bullae and ulcers while the second didn’t have any obvious bullae. Initial clinical diagnoses did not consider BP. Punch skin biopsy was done in both cases that revealed histologic features confirming BP. Clinicians should have high index of suspicion of BP even in cases of localized chronic wound or recurrent ulcers irrespective of the age of patient.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87511744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-24DOI: 10.18203/issn.2455-4529.intjresdermatol20232543
Anmol Bhargava, V. Kharkar, S. Saini
Lichen nitidus (LN) is a chronic inflammatory lichenoid dermatosis, commonly seen in childhood or early adulthood. In this case series, we studied the various dermoscopic features of LN and correlate them with clinical variants, duration of disease and histopathology. A total of 20 patients of LN were studied. The mean age was 25.7 years with 45% and 55% male and female, respectively. The median duration of disease was 6 months. The dermoscopic findings seen on non-polarizing mode were-shiny elevated surface with absence of skin markings (100%), scaling (70%), radial ridges (50%) and central depression (35%). Findings seen on polarizing mode were-hypopigmentation (100%), brown shadow (70%), linear vessels (65%), accentuation of surrounding reticulate pigment network (65%), diffuse erythema (45%). Newer findings seen were central grey-brown structureless areas (30%), speckled brown pigment (40%), curvilinear vessels (50%), branching/serpentine vessels (20%), radial vessels (10%), white dots and streaks (30%) and ring-in-ring appearance (5%). LN presents fairly distinctive dermoscopic features and dermoscopy can be a non-invasive, painless aid in differentiating it from close clinical differentials and avoid the need for a biopsy, especially in children.
{"title":"Dermoscopy of lichen nitidus: a study of 20 cases","authors":"Anmol Bhargava, V. Kharkar, S. Saini","doi":"10.18203/issn.2455-4529.intjresdermatol20232543","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20232543","url":null,"abstract":"Lichen nitidus (LN) is a chronic inflammatory lichenoid dermatosis, commonly seen in childhood or early adulthood. In this case series, we studied the various dermoscopic features of LN and correlate them with clinical variants, duration of disease and histopathology. A total of 20 patients of LN were studied. The mean age was 25.7 years with 45% and 55% male and female, respectively. The median duration of disease was 6 months. The dermoscopic findings seen on non-polarizing mode were-shiny elevated surface with absence of skin markings (100%), scaling (70%), radial ridges (50%) and central depression (35%). Findings seen on polarizing mode were-hypopigmentation (100%), brown shadow (70%), linear vessels (65%), accentuation of surrounding reticulate pigment network (65%), diffuse erythema (45%). Newer findings seen were central grey-brown structureless areas (30%), speckled brown pigment (40%), curvilinear vessels (50%), branching/serpentine vessels (20%), radial vessels (10%), white dots and streaks (30%) and ring-in-ring appearance (5%). LN presents fairly distinctive dermoscopic features and dermoscopy can be a non-invasive, painless aid in differentiating it from close clinical differentials and avoid the need for a biopsy, especially in children.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77960844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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