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Innovation of hyaluronic acid-protamine microparticles and their kinetics in vivo 透明质酸-鱼精蛋白微粒的创新及其体内动力学
Pub Date : 2016-01-01 DOI: 10.1142/S0129083516500054
S. Harada, S. Ehara, T. Segawa, K. Ishii, Takahiro Sato, T. Kamiya, K. Sera, S. Goto
The nanoparticles, which releases anticancer drug with response to radiation, were developed. Also, two categories were tested: (i) their ability to release anticancer drug in vitro; and (ii) their...
研究人员开发了这种纳米颗粒,它可以释放抗癌药物,对辐射有反应。此外,还测试了两类:(i)它们在体外释放抗癌药物的能力;(二)他们的……
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引用次数: 1
Heavy metal accumulation and the practical application of lichens as bioindicators for heavy metal pollution in surface soil 地衣作为表层土壤重金属污染生物指标的实际应用及重金属积累
Pub Date : 2016-01-01 DOI: 10.1142/S0129083517500024
Yuri Sueoka, M. Sakakibara, S. Sano, K. Sera
Levels of trace element pollution in surface soil have been estimated using soil analyses and leaching tests. These methods may reveal different results due to the effect of soil properties on the ...
利用土壤分析和浸出试验估计了表层土壤中的微量元素污染水平。这些方法可能会显示不同的结果,由于土壤性质的影响。
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引用次数: 0
Using the PIXE method to evaluate the characteristics of aerosols in Kumamoto City, Southwestern Japan, from March 2004 to March 2007 2004年3月- 2007年3月,用PIXE方法评价日本熊本市气溶胶特征
Pub Date : 2016-01-01 DOI: 10.1142/S0129083517500048
M. Sakai, K. Sera, S. Goto
Recently, atmospheric particles, including Asian dust, have attracted considerable attention because of their potential effects on the environment and human health. From March to May, a huge volume...
最近,包括亚洲沙尘在内的大气颗粒因其对环境和人类健康的潜在影响而引起了相当大的关注。从3月到5月,大量…
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引用次数: 0
Use of a silicon drift detector (SDD) in the quantitative analysis of in-air PIXE 硅漂移检测器(SDD)在空气中PIXE定量分析中的应用
Pub Date : 2016-01-01 DOI: 10.1142/S012908351750005X
K. Sera, S. Goto, T. Hosokawa, Y. Saitoh
In the present study, we used a silicon drift detector (SDD) for the quantitative analysis of in-air PIXE. First, we examined the basic performances of the detector. We found that the shift of the ...
在本研究中,我们使用硅漂移检测器(SDD)对空气中的pxie进行定量分析。首先,我们检查了探测器的基本性能。我们发现……
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引用次数: 1
Elemental concentration in the hair taken from healthy people for the past 20 years — 2. Sex-specific differences and changes with age 过去20年健康人头发中的元素浓度- 2。性别差异和年龄变化
Pub Date : 2016-01-01 DOI: 10.1142/S0129083516500042
K. Sera, S. Goto, T. Hosokawa, C. Takahashi, J. Itoh, Y. Saitoh, S. Futatsugawa
A standard-free method for untreated hairs has been applied to quantitative analysis of the hairs taken from 1256 healthy people living in the Iwate prefecture, Japan. It was found that there are c...
对居住在日本岩手县的1256名健康人的头发采用了一种未经处理的无标准方法进行定量分析。我们发现有……
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引用次数: 2
Detection of a gas region in a human body across a therapeutic carbon beam by measuring low-energy photons 通过测量低能光子的治疗性碳束来检测人体的气体区域
Pub Date : 2016-01-01 DOI: 10.1142/S0129083516500078
M. Yamaguchi, Y. Nagao, N. Kawachi, T. Satoh, S. Fujimaki, T. Kamiya, K. Torikai, H. Shimada, H. Sugai, M. Sakai, K. Arakawa, T. Nakano
We studied feasibility of detection of a gap which is located across a beam track by measuring low-energy (63–68 keV) photons generated by beam irradiation. An experiment was performed with the Heavy Ion Medical Accelerator in Chiba (HIMAC). A 12C beam having 290 MeV/u was injected on a target consisting of two acrylic blocks. These two blocks were placed with a 10 mm gap along the beam axis. A detection system consisting of a semiconductor detector, a lead collimator having a slit, and borated polyethylene blocks was placed on a movable stage to detect low-energy photons emitted perpendicularly to the beam axis. The position of the detection system was moved at 2 mm intervals along the beam axis. It was found that the yield of 63–68 keV photons was clearly correlated with the position of the detection system. The position at which the yield curve had the lowest value agreed with the gap position. We also confirmed that the experimental result was well reproduced by a Monte Carlo simulation that includes generation of secondary electron bremsstrahlung.
我们研究了通过测量束流辐照产生的低能光子(63-68 keV)来探测束流轨迹间隙的可行性。在千叶重离子医用加速器(HIMAC)上进行了实验。具有290 MeV/u的12C光束被注入到由两个丙烯酸块组成的目标上。这两个块沿着梁轴放置10毫米的间隙。一个由半导体探测器、带狭缝的引线准直器和硼化聚乙烯块组成的探测系统被放置在一个可移动的平台上,以探测垂直于光束轴发射的低能光子。检测系统的位置沿光束轴每隔2mm移动一次。发现63 ~ 68 keV光子的产率与探测系统的位置有明显的相关关系。收益率曲线最低值的位置与缺口位置一致。通过蒙特卡罗模拟,我们也证实了实验结果可以很好地再现,其中包括二次电子轫致效应的产生。
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引用次数: 7
Elemental concentration in the hair taken from healthy people for the past 20 years — 1. Long-term changes over 20 years 过去20年健康人头发中的元素浓度- 1。20多年的长期变化
Pub Date : 2016-01-01 DOI: 10.1142/S0129083516500030
K. Sera, S. Goto, T. Hosokawa, C. Takahashi, J. Itoh, Y. Saitoh, S. Futatsugawa
We developed a standard-free method for untreated hairs and the method has been applied to quantitative analysis of more than 30,000 hairs taken from the people concerned in order to evaluate exposure to some toxic elements and intakes of essential elements. Besides these analyses, we have measured nearly 2000 hairs collected from healthy people in Japan over the past 20 years. It was found that concentrations of some elements, such as vanadium, chromium, manganese, copper and mercury, keep increasing up to the present. Such tendencies were particularly notable for female, while not clearly observed for male. Concentrations of some essential elements, such as calcium, magnesium and zinc, show no obvious long-term variations. On the other hand, iron and selenium show slightly decreasing tendencies. With regard to toxic elements, it was found that arsenic, chromium and mercury are tending to increase year by year.
我们为未经处理的头发开发了一种无标准的方法,并将该方法应用于从有关人员身上提取的3万多根头发的定量分析,以评估接触某些有毒元素和摄入必需元素的情况。除了这些分析,我们还测量了过去20年来从日本健康人群中收集的近2000根头发。研究发现,一些元素的浓度,如钒、铬、锰、铜和汞,一直持续增加到现在。这种趋势在女性中尤为明显,而在男性中则没有明显的观察到。一些必需元素的浓度,如钙、镁和锌,没有明显的长期变化。另一方面,铁和硒有轻微下降的趋势。有毒元素方面,砷、铬、汞有逐年增加的趋势。
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引用次数: 3
Micro-PIXE analysis on adsorbent of extraction chromatography for MA(III) recovery 萃取色谱法回收MA(III)吸附剂的微pixe分析
Pub Date : 2016-01-01 DOI: 10.1142/S0129083517500012
Y. Takahatake, Sou Watanabe, H. Kofuji, M. Takeuchi, K. Nomura, T. Satoh
Japan Atomic Energy Agency (JAEA) has been conducting research and development of MA(III) recovery from high level liquid waste (HLLW) by extraction chromatography technology for reduction in amount and environmental impact of radioactive waste. The behavior of adsorbed cations inside the adsorbent packed in a column is necessary to be evaluated for improvement of the adsorbent or flow-sheet to achieve targeted MA(III) recovery performance. In this paper, micro-PIXE analysis was carried out on the particles sampled from various positions of the column to reveal the behavior of cations inside the packed column with CMPO/SiO2-P adsorbent using RE(III) as simulated elements of MA(III). Simple experiment and data analysis were shown to be effective to reveal inside of the column, and formation and transportation of the adsorption bands were observed for some cations which are extractable by the CMPO extractant. Some part of Zr(IV) and Mo(VI) were found to remain inside the column without distinct transportation even after the elution operation. Those results will contribute to design more practical MA(III) recovery flow-sheet.
日本原子能机构(JAEA)一直在研究和开发利用萃取色谱技术从高放废液(HLLW)中回收MA(III),以减少放射性废物的数量和对环境的影响。为了改进吸附剂或流程,以实现目标MA(III)的回收性能,有必要对柱内吸附剂内吸附阳离子的行为进行评估。本文采用RE(III)作为MA(III)的模拟元素,对柱上不同位置采样的颗粒进行了微pixe分析,揭示了CMPO/SiO2-P吸附剂填充柱内阳离子的行为。简单的实验和数据分析表明,CMPO萃取剂对部分阳离子的吸附带的形成和迁移是有效的。洗脱后仍有部分Zr(IV)和Mo(VI)残留在柱内,没有明显的迁移。这些结果将有助于设计更实用的MA(III)回收流程。
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引用次数: 1
Statistical aspects of variations in hair mineral measurements 头发矿物质测量变化的统计方面
Pub Date : 2016-01-01 DOI: 10.1142/S0129083517500036
K. Kataoka, Tomomi Yamada, Todd Saunders, T. Takatsuji, K. Sera, Tsuyoshi Nakamura, Y. Nose
The objective of this study is to examine the variations in hair mineral concentrations measured by particle induced X-ray emission (PIXE). As the concentrations reflect the historical profile of m...
本研究的目的是通过粒子诱导x射线发射(PIXE)检测头发矿物质浓度的变化。浓度反映了m的历史剖面。
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引用次数: 1
Observation of ferrokinetics in a plant using the micron RI imaging system 用微米磁共振成像系统观察植物的铁动力学
Pub Date : 2016-01-01 DOI: 10.1142/S0129083516500029
T. Maruyama, K. Ishii, M. Fujiwara, S. Matsuyama, A. Terakawa, H. Arai, Y. Saneshige
We succeeded in observation of ferrokinetics in a plant (20 days radish) using the micron RI imaging which was previously developed in our laboratory, by improving two criteria: (i) adjustment of t...
我们利用先前在我们实验室开发的微米RI成像技术成功地观察了植物(20天萝卜)的铁动力学,通过改进两个标准:(i)调整t…
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引用次数: 0
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International Journal of PIXE
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