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Visual outcome of cataract surgery in paediatric uveitis 小儿葡萄膜炎白内障手术的视觉效果
Pub Date : 2024-05-15 DOI: 10.18231/j.ijooo.2024.007
Natasha Radhakrishnan, Anil Radhakrishnan, Suma Balan, Pooja Kandula
1. To analyse the visual outcome in patients of paediatric uveitis who underwent cataract surgery; 2. To analyse the post-operative complications of cataract surgery in paediatric uveitis.Retrospective observational study was done on patients of uveitis who underwent cataract surgery. Patients who were under 18 years and co-operative for examination were included.They underwent Phacoaspiration with posterior chamber IOL implantation by a single surgeon after 3 months of activity free interval, BCVA(in Log MAR) in every follow up, anterior segment examination using slit lamp and posterior segment examination using IDO, post-operative complications and Intra ocular pressure was recorded using Noncontact tonometer.Uveitis was classified using the SUN classification of uveitis. Use of corticosteroids, biologics and immunosuppressive drug were collected at each visit. Total of 18 subjects diagnosed with cataract as a complication of uveitis & undergone cataract surgery were studied (6 were females, 12 were males) 9 had anterior uveitis, 1had intermediate uveitis and 5 had pan uveitis. JRA (66.7%) was the most common cause identified. Improvement in vision from baseline was observed post-surgery at the end of first, third and 6th month which was statistically significant (P- Value <0.05). Average duration of disease before they underwent surgery was 18 months. Most common post op complication was posterior capsular opacification (50 %), others include secondary glaucoma (38.9), exudative retinal detachment (5.6%) and Vitritis (22.2%)Unlike adult uveitic patients, the surgical management of paediatric uveitic cataract is both challenging and controversial, and the surgery itself has been associated with poor visual outcomes. However, our study had shown that with implantation of IOL, good immunosuppressants and control of the disease can give these children a good visual outcome.
1.分析接受白内障手术的儿童葡萄膜炎患者的视觉效果;2.分析儿童葡萄膜炎白内障手术的术后并发症。该研究对接受白内障手术的葡萄膜炎患者进行了回顾性观察研究,纳入的患者年龄均在 18 岁以下,并对检查持合作态度。在间隔 3 个月无活动后,由一名外科医生为患者进行了超声乳化手术,并植入了后房型人工晶体,每次随访均进行了 BCVA(对数 MAR)检查,使用裂隙灯进行了前段检查,使用 IDO 进行了后段检查,使用非接触式眼压计记录了术后并发症和眼压。每次就诊时都会收集使用皮质类固醇、生物制剂和免疫抑制剂的情况。共有 18 名被诊断为葡萄膜炎并发白内障并接受了白内障手术的受试者接受了研究(女性 6 人,男性 12 人),其中 9 人患有前葡萄膜炎,1 人患有中间葡萄膜炎,5 人患有泛葡萄膜炎。JRA(66.7%)是最常见的病因。手术后第一、第三和第六个月末,患者的视力较基线有明显改善,且具有统计学意义(P 值小于 0.05)。手术前的平均病程为 18 个月。最常见的术后并发症是后囊不透明(50%),其他并发症包括继发性青光眼(38.9%)、渗出性视网膜脱离(5.6%)和葡萄膜炎(22.2%)。然而,我们的研究表明,通过植入人工晶体、使用良好的免疫抑制剂和控制病情,可以为这些儿童带来良好的视觉效果。
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引用次数: 0
Imaging signatures in diffuse choroidal hemangioma in a case of sturge weber syndrome 斯特杰-韦伯综合征病例中弥漫性脉络膜血管瘤的成像特征
Pub Date : 2024-02-15 DOI: 10.18231/j.ijooo.2023.047
Rinal Pandit, Dhaivat Shah, Deepanshu Agrawal, Sukanya Gorhe, Neha Sharma
Sturge–Weber syndrome (SWS) is a rare congenital neurocutaneous disorder characterized by facial port-wine stain, leptomeningeal hemangiomas, and ocular manifestations such as glaucoma and diffuse choroidal hemangioma (DCH). DCH is a benign vascular lesion characteristically seen in up to 50% of patients affected with SWS. Diffuse choroidal hemangioma can cause refractive error, foveal distortion, and exudative retinal detachment and contribute to vision loss. We report a case of a young male with SWS and a unilateral DCH with characteristic imaging features.
斯特吉-韦伯综合征(Sturge-Weber Syndrome,SWS)是一种罕见的先天性神经皮肤疾病,以面部葡萄酒色斑、脑外血管瘤以及青光眼和弥漫性脉络膜血管瘤(DCH)等眼部表现为特征。弥漫性脉络膜血管瘤是一种良性血管病变,通常见于高达 50%的 SWS 患者。弥漫性脉络膜血管瘤可引起屈光不正、眼窝变形和渗出性视网膜脱离,导致视力下降。我们报告了一例患有 SWS 和单侧 DCH 的年轻男性患者的病例,该病例具有特征性的影像学特征。
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引用次数: 0
Clinical outcome in patients with 4- point scleral fixated intraocular lens: Our experience 4 点巩膜固定眼内透镜患者的临床疗效:我们的经验
Pub Date : 2024-02-15 DOI: 10.18231/j.ijooo.2023.040
Kaiyoor Surya Divyalakshmi, Chaithanya Blevender Singh, Rashmi Shambu
Visual rehabilitation following cataract surgery with compromised capsular bag includes various options like anterior chamber (ACIOL), fixation to the iris (Iris claw IOL), or fixation to the sclera (SFIOL), as a primary or secondary procedure. We studied the clinical outcome in patients who underwent 4- point fixation of SFIOLs. Retrospective data analysis of fourteen patients who underwent sclera fixated intraocular lens implantation from 2016 to 2018 at our institute under standard operative conditions was done. The postoperative vision by three months ranged from LogMAR 1.0 – 0.2, out of fourteen patients, BCVA in 60 % of the patients ranged from LogMAR 0.3-0.2 which was maintained at six months follow up with minimal complications. 4- point fixation of scleral fixated IOL is a good option with favourable outcome, in aphakics who are not ideal candidates for iris claw lens.
囊袋受损的白内障手术后的视觉康复包括多种选择,如前房固定(ACIOL)、虹膜固定(虹膜爪 IOL)或巩膜固定(SFIOL),作为主要或辅助手术。我们研究了接受 4 点固定 SFIOL 的患者的临床疗效。我们对2016年至2018年在我院接受巩膜固定眼内人工晶体植入术的14名患者进行了标准手术条件下的回顾性数据分析。14名患者中,60%的患者术后三个月的视力在LogMAR 1.0 - 0.2之间,BCVA在LogMAR 0.3-0.2之间,随访六个月后视力保持不变,并发症极少。对于不适合使用虹膜爪晶状体的无晶体眼患者来说,巩膜固定人工晶体的四点固定是一个不错的选择,而且效果良好。
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引用次数: 0
Pediatric ocular tumors: An overview 小儿眼部肿瘤:概述
Pub Date : 2024-02-15 DOI: 10.18231/j.ijooo.2023.036
Anuradha Raj, Pratibha Sahu
The majority of ocular tumors in children are benign, but specific malignant neoplasms pose a risk to both life and vision. It's indeed crucial for pediatricians to be aware of ocular tumors in children, as early detection and proper management can significantly impact the child's health and vision. As a result, swift recognition and timely referral of patients to an ocular oncologist are imperative for effective clinical management. This article provides an overview of general concepts surrounding ocular tumors in the pediatric age group, offering brief insights into the clinical features and management of significant tumors affecting the eyelids, conjunctiva, intraocular structures, and orbit.
大多数儿童眼部肿瘤是良性的,但特定的恶性肿瘤会对生命和视力构成威胁。儿科医生对儿童眼部肿瘤的认识确实至关重要,因为早期发现和适当治疗会对儿童的健康和视力产生重大影响。因此,迅速识别并及时将患者转诊至眼部肿瘤专科医生是有效临床管理的当务之急。本文概述了有关儿童眼部肿瘤的一般概念,简要介绍了影响眼睑、结膜、眼内结构和眼眶的重要肿瘤的临床特征和治疗方法。
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引用次数: 0
Reading performance in school going children with visual function anomalies 视功能异常学童的阅读能力
Pub Date : 2024-02-15 DOI: 10.18231/j.ijooo.2023.038
S. Kadir, Sunanda Sarkhel, Sayantan Chakraborty, R. P. Maurya, Nilufa Akter, Masihuzzaman, Gaurav Kumar Bhardwaj, Mastura Khatun
To compare reading performance in children with and without visual function anomalies. This cross-sectional study was carried out from May 2021 to April 2022 in a tertiary eye hospital of Bangladesh. This study included patients with 6-15 years of age who visited at Vision Therapy clinic. CISS-score was used to identify the asthenopia complaints and reading difficulties while having a normal vision and normal retinal function only selected for recruitment. Reading error, accuracy and reading speed were assessed with an N-notation chart with an N6 target size and the time taken to complete the task was recorded with a stopwatch. Both univariate and bivariate tables are used for analysis. Statistics analysis was performed accordingly, and the level of significance used was at 0.05. Out of 200 subjects, 46.5% boys and 53.5% girls. Of the total, 15.5% had NVF. The mean age of the participants was 12.04 (±2.44) years. Children with AVF had a higher number of reading errors and non-significant negative correlation (AVF=7.64 (±5.19); NVF 6.55 (±3.67); (r = -1.00, p=0.157). Lower Reading accuracy was noted in AVF as correlated to NVF and non-significant negative correlation (AVF=86.11 (±14.84); NVF=86.43 (±13.12); (r= -0.008, p=0.912). Similarly, lower reading speed was noted in AVF as correlated to NVF and non-significant negative correlation (AVF=79.47 (±39.20) wpm; NVF=84.51±36.84 wpm; (r= -0.047, p=0.507). A statistically significant difference was seen between AVF and NVF (p=0.001 at a 95% Confidence Interval of the differences). Children in the 1 to 5 grades presented a higher risk of reading impairment than the 6 to 10grades. Higher reading speed (112±20.69wpm) was noted in 10 grade. In this study, it was observed that poor reading performance is linked to abnormal visual function in school-aged children, but visual function and reading performance are not positively related.
比较视功能异常儿童与非视功能异常儿童的阅读能力。这项横断面研究于 2021 年 5 月至 2022 年 4 月在孟加拉国一家三级眼科医院进行。研究对象包括在视力治疗诊所就诊的 6-15 岁儿童。研究人员使用 CISS 评分来确定散光主诉和阅读困难,而视力正常和视网膜功能正常的患者仅被选中作为研究对象。阅读误差、准确性和阅读速度是通过 N6 目标大小的 N 标记图进行评估的,并用秒表记录完成任务所需的时间。单变量和双变量表格均用于分析。据此进行统计分析,显著性水平为 0.05。在 200 名受试者中,男生占 46.5%,女生占 53.5%。其中,15.5%的受试者患有NVF。受试者的平均年龄为 12.04 (±2.44) 岁。患有 AVF 的儿童阅读错误较多,且两者之间存在不显著的负相关(AVF=7.64 (±5.19); NVF 6.55 (±3.67); (r = -1.00, p=0.157)。与 NVF 相比,AVF 的阅读准确率较低,且呈非显著负相关(AVF=86.11 (±14.84); NVF=86.43 (±13.12); (r= -0.008, p=0.912)。同样,AVF 的阅读速度也低于 NVF,两者呈非显著负相关(AVF=79.47 (±39.20) wpm; NVF=84.51±36.84 wpm; (r= -0.047, p=0.507))。在统计学上,AVF 和 NVF 之间存在明显差异(在差异的 95% 置信区间内,p=0.001)。1 至 5 年级儿童出现阅读障碍的风险高于 6 至 10 年级儿童。10年级儿童的阅读速度较快(112±20.69wpm)。本研究发现,学龄儿童阅读能力差与视觉功能异常有关,但视觉功能与阅读能力并不呈正相关。
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引用次数: 0
A comparative study of central corneal thickness in patients with diabetes and without diabetes mellitus 糖尿病患者和非糖尿病患者中央角膜厚度的比较研究
Pub Date : 2024-02-15 DOI: 10.18231/j.ijooo.2023.042
Lessitha N K, Haleema A, Mohammed Haneef, Shalet Paul
 Diabetes mellitus (DM) is becoming increasingly and seriously prevalent lifestyle health problem worldwide. Up to 70% of diabetic patients can develop corneal changes and are also difficult to manage. Several studies were done to find out the morphological changes in cornea in type 2 DM, but the results are highly variable. Central corneal thickness (CCT) is widely considered as a constant parameter, so are measured only once during follow up in our daily clinical practice. Here we study the effect of diabetes over CCT, for a better understanding of the impact of diabetes over CCT.A comparative observational study of one and half years done among 106 diabetes and 106 non diabetic patients between 35 to 75 years old, attending ophthalmology OPD. CCT of both eyes was measured and mean CCT and was compared between diabetic and non-diabetic groups, among different subgroups of diabetic subjects and other parameters.CCT was thicker among diabetic groups (553.4434um) than non-diabetic groups (549.8491) but was not statistically significant according to our study. But there was statistically significant (p value 0.000165) thickening with increasing grades of diabetic retinopathy (DR) (mild DR (535.4524), moderate DR (543) and PDR (591.5)). Our study concludes that DM is associated with thicker cornea; hence CCT values can vary with time in DM. So repeated CCT measurements for corrected IOP values is advised and warranted in DM patients for proper management of IOP.
糖尿病(DM)正成为全球日益严重的生活方式健康问题。多达 70% 的糖尿病患者会出现角膜病变,而且难以控制。为了解 2 型糖尿病患者角膜的形态变化,已进行了多项研究,但结果差异很大。角膜中央厚度(CCT)被广泛认为是一个恒定参数,因此在日常临床实践中只需随访测量一次。在此,我们研究了糖尿病对 CCT 的影响,以便更好地了解糖尿病对 CCT 的影响。该研究对 106 名 35 岁至 75 岁到眼科门诊就诊的糖尿病患者和非糖尿病患者进行了为期一年半的观察比较,测量了他们双眼的 CCT 值,并比较了糖尿病组和非糖尿病组、糖尿病受试者不同亚组的平均 CCT 值及其他参数。但随着糖尿病视网膜病变(DR)等级(轻度DR(535.4524)、中度DR(543)和重度DR(591.5))的增加,视网膜增厚有统计学意义(P 值为 0.000165)。我们的研究得出结论,DM 与角膜变厚有关;因此,DM 患者的 CCT 值会随着时间的推移而变化。因此,建议并有必要对 DM 患者重复测量 CCT 值,以校正眼压值,从而对眼压进行适当管理。
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引用次数: 0
Biomarkers of oxidative stress and inflammation in dry eye disease 干眼症中氧化应激和炎症的生物标志物
Pub Date : 2024-02-15 DOI: 10.18231/j.ijooo.2023.035
R. P. Maurya, Sneha Gupta, Shalini Ranjan
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引用次数: 0
A comparative study of central corneal thickness in patients with diabetes and without diabetes mellitus 糖尿病患者和非糖尿病患者中央角膜厚度的比较研究
Pub Date : 2024-02-15 DOI: 10.18231/j.ijooo.2023.042
Lessitha N K, Haleema A, Mohammed Haneef, Shalet Paul
 Diabetes mellitus (DM) is becoming increasingly and seriously prevalent lifestyle health problem worldwide. Up to 70% of diabetic patients can develop corneal changes and are also difficult to manage. Several studies were done to find out the morphological changes in cornea in type 2 DM, but the results are highly variable. Central corneal thickness (CCT) is widely considered as a constant parameter, so are measured only once during follow up in our daily clinical practice. Here we study the effect of diabetes over CCT, for a better understanding of the impact of diabetes over CCT.A comparative observational study of one and half years done among 106 diabetes and 106 non diabetic patients between 35 to 75 years old, attending ophthalmology OPD. CCT of both eyes was measured and mean CCT and was compared between diabetic and non-diabetic groups, among different subgroups of diabetic subjects and other parameters.CCT was thicker among diabetic groups (553.4434um) than non-diabetic groups (549.8491) but was not statistically significant according to our study. But there was statistically significant (p value 0.000165) thickening with increasing grades of diabetic retinopathy (DR) (mild DR (535.4524), moderate DR (543) and PDR (591.5)). Our study concludes that DM is associated with thicker cornea; hence CCT values can vary with time in DM. So repeated CCT measurements for corrected IOP values is advised and warranted in DM patients for proper management of IOP.
糖尿病(DM)正成为全球日益严重的生活方式健康问题。多达 70% 的糖尿病患者会出现角膜病变,而且难以控制。为了解 2 型糖尿病患者角膜的形态变化,已进行了多项研究,但结果差异很大。角膜中央厚度(CCT)被广泛认为是一个恒定参数,因此在日常临床实践中只需随访测量一次。在此,我们研究了糖尿病对 CCT 的影响,以便更好地了解糖尿病对 CCT 的影响。该研究对 106 名 35 岁至 75 岁到眼科门诊就诊的糖尿病患者和非糖尿病患者进行了为期一年半的观察比较,测量了他们双眼的 CCT 值,并比较了糖尿病组和非糖尿病组、糖尿病受试者不同亚组的平均 CCT 值及其他参数。但随着糖尿病视网膜病变(DR)等级(轻度DR(535.4524)、中度DR(543)和重度DR(591.5))的增加,视网膜增厚有统计学意义(P 值为 0.000165)。我们的研究得出结论,DM 与角膜变厚有关;因此,DM 患者的 CCT 值会随着时间的推移而变化。因此,建议并有必要对 DM 患者重复测量 CCT 值,以校正眼压值,从而对眼压进行适当管理。
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引用次数: 0
Ophthalmoplegia syndrome or tolosa hunt syndrome – A review 眼球震颤综合征或托罗萨-亨特综合征--综述
Pub Date : 2024-02-15 DOI: 10.18231/j.ijooo.2023.037
Sunil Kumar
Ophthalmoplegia syndrome or Tolosa Hunt syndrome (THS) is a rare severe unilateral periorbital headache associated with painful and restricted eye movements (ophthalmoplegia) with no visual deterioration. It is associated with choric inflammation with granulomatous deposition in cavernous sinus and at superior orbital fissure. This article provides a detail outlook of this syndrome that along with pathophysiology, the present diagnostic considerations and management insights on Tolosa-Hunt syndrome through review of published article.
眼球震颤综合征或托罗萨-亨特综合征(THS)是一种罕见的严重单侧眶周头痛,伴有疼痛和眼球运动受限(眼球震颤),但无视力衰退。它与海绵窦和眶上裂肉芽肿沉积的蝶窦炎症有关。本文通过回顾已发表的文章,详细介绍了托洛萨-亨特综合征的病理生理学、目前的诊断注意事项和治疗方法。
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引用次数: 0
Conjunctival chemosis unfolding to adrenocortical carcinoma: A case report 结膜化脓性肾上腺皮质癌:病例报告
Pub Date : 2024-02-15 DOI: 10.18231/j.ijooo.2023.045
Sreeja Sreenivasan, Anjali Shaji, S. Thulaseedharan
Conjunctival chemosis is a common ocular sign in clinical practice and is a non-specific clinical entity. We report a case of a 53-year-old male who presented with bilateral conjunctival edema due to adrenocortical carcinoma. Adrenocortical carcinoma is a very rare adrenal gland tumor with an annual global incidence of about 1- 2 per million population. The definitive diagnosis was made by detailed ophthalmic and systemic evaluation, imaging techniques, histopathological examination (HPE) and immunohistochemistry (IHC). This case report emphasizes the significance of complete evaluation of a patient, even in a specialty clinic.
结膜化脓是临床上常见的眼部症状,也是一种非特异性的临床表现。我们报告了一例 53 岁男性因肾上腺皮质癌导致双侧结膜水肿的病例。肾上腺皮质癌是一种非常罕见的肾上腺肿瘤,全球年发病率约为 1-2 百万人。通过详细的眼科和全身评估、成像技术、组织病理学检查(HPE)和免疫组化(IHC),最终确诊了该患者。本病例报告强调了对患者进行全面评估的重要性,即使在专科诊所也是如此。
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引用次数: 0
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IP International Journal of Ocular Oncology and Oculoplasty
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