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Case report – Chronic intra-orbital foreign body 病例报告-慢性眶内异物
Pub Date : 2023-05-15 DOI: 10.18231/j.ijooo.2023.011
Bindu Malini Mudduveerappa, Prabhakar S K, Sakshi Ramnani
Intraocular or orbital foreign bodies when small or due to trivial trauma often go unnoticed or missed during examination especially a wooden foreign body. They can present as non-healing wounds and discharging fistulas with signs of chronic inflammation, cellulitis, foreign body granuloma or ocular complications such as corneal scars, traumatic cataract, hyphema, glaucoma, retinal tear and detachment. This case report highlights the importance of detailed history taking and proper diagnosis which plays an important role in the management of such cases.
眼内或眶内异物如体积小或因外伤引起,在检查时常被忽视或遗漏,尤其是木质异物。它们可以表现为无法愈合的伤口和排出的瘘管,并伴有慢性炎症、蜂窝组织炎、异物肉芽肿或眼部并发症,如角膜疤痕、外伤性白内障、前房积血、青光眼、视网膜撕裂和脱离。本病例报告强调详细病史和正确诊断的重要性,这在此类病例的管理中起着重要作用。
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引用次数: 0
Treatment of ocular surface squamous neoplasia with topical 1% 5-fluorouracil 外用1% 5-氟尿嘧啶治疗眼表鳞状瘤变
Pub Date : 2023-05-15 DOI: 10.18231/j.ijooo.2023.010
Bindu Malini Mudduveerappa, F. George, Darshan S M, V. K. Anklesaria, Pooja H. Chabbi
Ocular surface squamous neoplasia (OSSN) is the most common type of ocular tumour. An eighty-year-old man with an elevated lesion in the right eye was diagnosed to have OSSN. 1% topical 5-FU was started as an intermittent treatment. Examination during each visit showed consistent reduction in size of lesion. The patient showed complete regression with no recurrence following treatment with 1% 5-FU at 3 months from presentation. Tropical treatment with 1% 5-FU provides excellent prognosis in cases of OSSN.
眼表鳞状肿瘤(OSSN)是最常见的眼部肿瘤类型。一位八十岁的男性右眼病变升高被诊断为OSSN。1%局部5-FU作为间歇性治疗开始。每次就诊时的检查均显示病变大小一致减小。患者在发病后3个月接受1% 5-FU治疗后完全消退,无复发。1% 5-FU的热带治疗为OSSN患者提供了良好的预后。
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引用次数: 0
Occular manifestation of a case of lamellar ichthyosis 板层状鱼鳞病的眼部表现
Pub Date : 2023-05-15 DOI: 10.18231/j.ijooo.2023.008
Dhruvil V Nayak, H. Trivedi, Prapti Rathod
A baby full term born of LSCS to a otherwise healthy mother was referred for ophthalmology department. On ophthalmological torch light examination, the patient had equal upper and lower lid bilateral ectropion. There was missing eye lashes noted. The anterior segment evaluation was found to be within normal limit without evidence of corneal opacities. Lamellar ichthyosis otherwise termed as Collodion baby is a infrequent disease; and there is no well-known management protocol. The Patient was managed conservatively by the use of Hydroxy propyl methyl cellulose (2% w/v) eye ointment and lubricant (Carboxy methyl cellulose 0.5%) eye drops. Thus, surgical intervention was avoided and patient was managed medically on ointments and drops
一个足月出生的婴儿LSCS,其他健康的母亲被转介到眼科。眼科火炬光检查,患者上、下眼睑双侧相等外翻。有缺失的眼睫毛。前段评估在正常范围内,无角膜混浊迹象。板层状鱼鳞病也被称为Collodion婴儿,是一种罕见的疾病;也没有众所周知的管理协议。患者使用羟基丙基甲基纤维素(2% w/v)眼膏和润滑剂(0.5%羧甲基纤维素)滴眼液保守治疗。因此,避免了手术干预,并对患者进行了药膏和滴剂的医学管理
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引用次数: 0
Anophthalmic socket syndrome: Management and cosmetic outcome 无眼窝综合征:管理和美容结果
Pub Date : 2023-05-15 DOI: 10.18231/j.ijooo.2023.001
Farzana Afzal, S. Sultana, Riffat Rashid, S. Kadir
To describe the management strategy and evaluate the outcome of Anophthalmic socket syndrome. This retrospective case study includes 40 patients with anophthalmic socket syndrome who attended the orbit and ocular oncology department of Ispahani Islamia Eye Hospital from January 1, 2018, to June 31, 2021 were included in this study. All the information regarding age, gender, initial pathology, type of initial surgery, implant, degree of contraction, the procedure of socket reconstruction, the management outcome and complication were recorded and analyzed correctly. 17 males (42.5%) and 23 females (57.5%) with a mean age of 24.47 years were included in the study. Trauma (30%) and Tumour (25%) were the main reasons for initial eye removal. Enucleation performed in 24 (60%) cases was the most common initial surgery. The primary implant was not done in 20 (50%) cases. Mild socket contraction (grade 1) was recorded in 10 (25%) cases. Moderate contraction (grade 2 and 3) in 25(62.5%) cases and severe contraction (grade 4) in 5(12.5%) cases were recorded. Only fornix forming suture was done in 10 (25%) cases, mucous membrane graft (MMG) was done in 27 (67.5%) cases and dermis fat graft was done in 3 (7.5%) cases. All the patients were followed up routinely for six months. The outcome was good in 16 (40%) cases, acceptable in 20 (50%), and poor in 4 (10%) cases. A common complication was infection (5%) and fat atrophy (5%).: Anophthalmic socket syndrome remains a challenging entity for the oculoplastic surgeon. Multiple factors help to determine the overall prognosis of socket reconstruction. The goal of management is to provide a socket that can maintain a cosmetically acceptable prosthesis. Timely detection, proper correction of the underlying pathology and a high level of care directly correlate with expected surgical outcomes.
目的:探讨无眼窝综合征的治疗策略及治疗效果。本回顾性病例研究纳入了2018年1月1日至2021年6月31日在Ispahani Islamia眼科医院眼眶和眼肿瘤科就诊的40例无眼窝综合征患者。对患者的年龄、性别、初始病理、初始手术类型、种植体、收缩程度、窝口重建方式、处理结果及并发症等进行记录和分析。男性17例(42.5%),女性23例(57.5%),平均年龄24.47岁。创伤(30%)和肿瘤(25%)是最初摘除眼球的主要原因。24例(60%)患者的初始手术为眼球摘除术。20例(50%)患者未进行一期种植。10例(25%)患者出现轻度眼眶收缩(1级)。中度收缩(2级和3级)25例(62.5%),重度收缩(4级)5例(12.5%)。仅穹窿形成缝合10例(25%),黏膜移植27例(67.5%),真皮脂肪移植3例(7.5%)。对所有患者进行了为期6个月的常规随访。结果良好16例(40%),可接受20例(50%),差4例(10%)。常见的并发症是感染(5%)和脂肪萎缩(5%)。对于眼整形外科医生来说,无眼窝综合征仍然是一个具有挑战性的问题。多种因素有助于确定眶内重建的整体预后。治疗的目标是提供一个可以维持一个美容上可接受的假体的插槽。及时发现、正确纠正潜在病理和高水平的护理与预期的手术结果直接相关。
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引用次数: 0
Clinical presentations, epidemiology and management of COVID-19 associated Mucor mycosis in a tertiary care hospital in South India 南印度一家三级医院COVID-19相关毛霉菌病的临床表现、流行病学和管理
Pub Date : 2023-05-15 DOI: 10.18231/j.ijooo.2023.002
N. Balakrishna, Madhusudhan C N, R. R, D. Prakash, K. Satish
To study the statistics of the epidemiology, co-morbidities, clinical presentations, management and prognosis of the study group. This is a retrospective study conducted in a tertiary care hospital in South India, among 100 subjects, between May 2021 and August 2021 when the Mucor mycosis cases were frequently being diagnosed and treated amongst COVID-19 infected patients. The results showed that 34.0% were between 51-60 years with 100% patients confirmed COVID positive through RTPCR tests. 86.0% had confirmed mucor on CT scan. 50.0% had both eyes vision of 6/60 on presentation. 67.% had periorbital swelling with 51% having prior co-morbidities.63.0% patients received tablet Posaconazole 30mg as medical treatment and 60.0% required no surgical management.10.0% required orbital exenteration and 21.0% required partial maxillectomy.2% experienced orbital apex syndrome as associated complications.97.0% were discharged post treatment with 3% mortality. There was a positive correlation of medical management with respect to anterior segment and posterior segment findings P<0.001 and P=0.79. There was a positive correlation between surgical treatment and anterior and posterior segment findings P<0.001 and P=0.43. There was a positive correlation between co-morbidities and death P<0.001, with 32.0% uncontrolled diabetics. This study shows that immune suppression is directly related to infectivity by mucor mycosis. In order to contain symptomatology and grave prognosis amongst patients, early diagnosis, affordable treatment and follow-up including patient education about the etiology and pathogenesis of the disease must be available.
目的:对研究组的流行病学、合并症、临床表现、治疗及预后进行统计。这是一项回顾性研究,在2021年5月至2021年8月期间,在印度南部的一家三级保健医院对100名受试者进行了研究,当时在COVID-19感染患者中经常诊断和治疗毛霉菌病病例。结果显示,年龄在51-60岁之间的患者占34.0%,100%的患者通过RTPCR检测呈阳性。86.0% CT证实有毛癣。50.0%就诊时双眼视力为6/60。67.63.0%的患者接受泊沙康唑片剂30mg内科治疗,60.0%的患者无需手术治疗,10.0%的患者需要眼眶清除术,21.0%的患者需要部分上颌切除术。术后97.0%患者出院,病死率3%。医疗管理与前段和后段检查结果呈正相关P<0.001和P=0.79。手术治疗与前后段表现呈正相关,P<0.001, P=0.43。合并症与死亡呈正相关,P<0.001,其中32.0%为未控制糖尿病。本研究表明免疫抑制与毛霉菌感染有直接关系。为了控制患者的症状和严重预后,必须提供早期诊断、负担得起的治疗和随访,包括对患者进行有关该病病因和发病机制的教育。
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引用次数: 0
Double jeopardy - Graft infection by Scedosporium apiospermum 双重危险-移植物感染的尖精子隐孢子虫
Pub Date : 2023-05-15 DOI: 10.18231/j.ijooo.2023.007
S. Kausar, M. R
Presenting a case report of corneal graft infection by an opportunistic fungus, , which is reported to be resistant to many antifungals. Antibiotic sensitivity of the organism and management of such infections has been discussed.
提出一例角膜移植物感染的机会性真菌,,据报道,这是耐多种抗真菌。抗生素敏感性的有机体和管理的这种感染已被讨论。
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引用次数: 0
A comparative study on slow down progression of myopia using atropine 0.01% in children 0.01%阿托品延缓儿童近视进展的比较研究
Pub Date : 2023-05-15 DOI: 10.18231/j.ijooo.2023.005
Syeda Sadia Ikram, D. S., S. Puri
The aim of the study was to determine the efficacy of lower concentration of Atropine 0.01% in promoting unaided visual acuity and slowing down the progression of myopia in children over 6 months. It was a hospital-based comparative study in the outpatient department of Ophthalmology, AL, LT, ACD, PPD, SPD, PGP were taken by Lenstar and Lensometer.The Comparative study was performed on 60 children from 9 to 15 years age group with initial myopic spherical equivalence from 0.5 to 6.00 D. The children were screened for visual acuity for distance and near using Snellen’s chart. Cycloplegic Refraction was done to know the presence of Refractive Errors. This study was approved by IRB Ethical Committee. (SCAHS/IRB/2022/JULY/420).The inclusion criteria include Ammetropic children with no binocular vision anomalies and no history of ocular disease. The primary outcome was the rate of myopic progression after 6 months. The participants were instructed to use Atropine 0.01% eye drops during night times for 6 months and the rate of myopic progression and the spherical equivalence, axial length, lens thickness, anterior chamber depth, photopic and scotopic pupil diameter were re-assessed to compare the progression of myopia in the children. Sixty children enrolled for six months study in which the mean progression of myopia was found to be within 0.27D and axial elongation shows 0.23 mm changes respectively, whereas there were no significant changes in the anterior chamber depth, lens thickness, photopic and scotopic pupil diameter before and after assessment in children. Spherical power, Axial Length, Anterior Chamber Depth, Lens Thickness, Photopic Pupil Diameter and Scotopic Pupil Diameter all showed significant progression from pre to post stages, with the average post reading deviating by 0.25 from the normal limits.
本研究的目的是确定0.01%低浓度阿托品在6个月以上儿童中促进独立视力和减缓近视进展的疗效。本研究是一项以医院为基础的眼科门诊比较研究,Lenstar和Lensometer分别测量AL、LT、ACD、PPD、SPD、PGP。采用Snellen’s视力表对60例初诊近视0.5 ~ 6.00 d的9 ~ 15岁儿童进行了比较研究。通过睫状体麻痹性屈光检查来了解屈光不正的存在。本研究已获IRB伦理委员会批准。(SCAHS / IRB / 2022 / / 420年7月)。纳入标准包括无双眼视力异常和无眼部疾病史的无屈光性儿童。主要观察指标为6个月后近视进展率。要求受试者在夜间使用0.01%阿托品滴眼液,连续6个月,并重新评估近视进展率和球面等效性、眼轴长度、晶状体厚度、前房深度、光瞳和暗瞳直径,比较儿童近视进展。60名儿童参加了为期6个月的研究,其中平均近视进展在0.27D以内,轴向伸长变化0.23 mm,而评估前后儿童前房深度、晶状体厚度、光瞳和暗瞳直径均无显著变化。球体度数、眼轴长度、前房深度、晶状体厚度、光瞳直径和暗瞳直径均表现出明显的变化,平均后读数与正常值相差0.25。
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引用次数: 0
Profile of cerebral visual impairment in children less than 7 years – A prospective observational study 7岁以下儿童脑视力障碍概况-一项前瞻性观察研究
Pub Date : 2023-05-15 DOI: 10.18231/j.ijooo.2023.004
N. S. Kumar, Malarvizhi Raman, Anuradha Sunder, Geethu Niruba
To study the incidence of cerebral visual impairment among children with history of perinatal neurological insult and congenital brain anomalies and to analyze the outcome following visual intervention programme. A prospective interventional study, examining 100 children less than 7 years over a period of 1 year. All children with history of perinatal hypoxia, neonatal hypoglycemia, neonatal seizures, infantile spasm, epilepsy, congenital hydrocephalus, congenital brain anomalies, CNS infections, traumatic brain injury and post cardiac surgery, excluding children with ocular visual impairment.  Of the 100 children studied, the incidence of CVI was 87%. The associated ocular problems were found to be low visual acuity seen in 85%, strabismus in 25%, refractive error in 39%, Nystagmus in 21% and oculomotor apraxia in 6%. The most common etiology was hypoxic ischemic encephalopathy, contributing to 30% of the cases and most common MRI findings were periventricular leukomalacia, seen in 42%. CVI Range was used for functional visual assessment. Visual intervention rather than visual stimulation was taught to the primary care giver and children were followed up every 3 months. 26% of children had improved in their functional vision after 6 months of Individualized intervention.  Early identification and individualized visual intervention, integrating them into many activities of the child across the whole day, form a crucial part of the visual outcome. Improvement in vision creates access to a world of cognitive and motor development. 
目的探讨围生期神经损伤及先天性脑异常患儿的脑视力损害发生率,并分析视力干预方案的效果。一项前瞻性干预性研究,对100名7岁以下儿童进行为期1年的调查。所有有围产期缺氧、新生儿低血糖、新生儿癫痫发作、婴儿痉挛、癫痫、先天性脑积水、先天性脑异常、中枢神经系统感染、外伤性脑损伤和心脏手术后病史的儿童,但有视力障碍的儿童除外。在研究的100名儿童中,CVI的发生率为87%。相关的眼部问题为:低视力占85%,斜视占25%,屈光不正占39%,眼球震颤占21%,动眼性失用症占6%。最常见的病因是缺氧缺血性脑病,占30%的病例,最常见的MRI表现是脑室周围白质软化,占42%。CVI范围用于功能视觉评价。对初级护理人员进行视觉干预而不是视觉刺激,每3个月对儿童进行随访。在个体化干预6个月后,26%的儿童的功能性视力得到改善。早期识别和个性化的视觉干预,将它们融入儿童一整天的许多活动中,形成了视觉结果的关键部分。视力的改善创造了进入认知和运动发展世界的机会。
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引用次数: 0
Periocular and orbital amyloidosis: A case series study 眼周和眼眶淀粉样变:一个病例系列研究
Pub Date : 2023-05-15 DOI: 10.18231/j.ijooo.2023.006
S. Kadir, G. Haider, Mukti Rani Mitra, R. P. Maurya, Nishat Parveen, Tanjila Hossain, Riffat Rashid, Md. Ismail Hossain, Narayon Chandra Bhowmik, S. Sultana
To present the demographic and clinical profile and management strategies of patients with periocular and orbital amyloidosis. This study retrospectively reviewed the clinical records of twelve patients with periocular and orbital amyloidosis between January 2011 and February 2019 in Bangladesh. Clinical evaluation and Imaging studies were helpful to diagnosis the patients, but surgical biopsy followed by histopathological study was done to confirm the diagnosis. All cases were investigated to rule out systemic amyloidosis with limited facility and no systemic involvement was found. Informed written consent for surgical procedure and Clinical photographs were taken for all patients for documentation and clinical research. The study included thirteen patients including nine male (69.2%) and four female (30.8%) patients. Among the patients, seven (53.8%) were unilateral and six (46.2%) were bilateral. Clinical signs and symptoms were visible or palpable periocular mass or tissue infiltration in all 13 (100%) cases, mechanical ptosis was observed in 6 (46.2%) cases, and proptosis or globe displacement was found in 4 (30.8%). Age ranges from 25 years to 65 years. The Mean age ± SD was 48.23 ± 10.64 years. Treatment modalities were mainly open surgical biopsy either excision (53.8%) or debulking (46.2%). Periocular and orbital amyloidosis may present with a wide spectrum of clinical findings depending on the location of the disease. The goal of treatment is to preserve function and to prevent sight-threatening complications.
目的:介绍眼周和眼窝淀粉样变患者的人口学特征、临床特点和治疗策略。本研究回顾性回顾了2011年1月至2019年2月期间孟加拉国12例眼周和眼窝淀粉样变患者的临床记录。临床评价和影像学检查有助于诊断,但手术活检和组织病理学检查证实了诊断。我们对所有病例进行了调查,以排除设施有限的全身性淀粉样变性,未发现全身性病变。所有患者均拍摄手术知情同意书和临床照片,用于文献记录和临床研究。本研究纳入13例患者,其中男性9例(69.2%),女性4例(30.8%)。单侧7例(53.8%),双侧6例(46.2%)。13例(100%)患者均可见或可触及眼周肿块或组织浸润,机械性上睑下垂6例(46.2%),眼球突出或眼球移位4例(30.8%)。年龄从25岁到65岁不等。平均年龄±SD为48.23±10.64岁。治疗方式主要为开放性手术活检,切除(53.8%)或减体积(46.2%)。眼周和眼窝淀粉样变可能表现出广泛的临床表现,这取决于疾病的位置。治疗的目标是保持功能和防止威胁视力的并发症。
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引用次数: 0
Viridocoria –Green reflex in immunocompromised cytomegalovirus retinitis patient 免疫功能低下巨细胞病毒性视网膜炎患者的绿反射
Pub Date : 2023-05-15 DOI: 10.18231/j.ijooo.2023.009
A. Sultana
We report a case of middle aged immunocompromised female with cytomegalovirus retinitis presenting with green reflex in pupillary y area of Right eye, her chief complaints were diminished vision in both eyes since one month, she was on HART for 3 years, discontinued for one and half year and again started after the advice of physician, apart from history, systemic and ocular examination done in detailed. BCVA, slit lamp examination, indirect ophthalmoscopy, FFA, B Scan and documentation done, Right eye was observed to note the further changes in fundus where as Left eye was treated with intra vitreal injection Ganciclovir to preserve the vison. Patient treated with intra vitreal Ganciclovir 500 micro grams, twice weekly with interval of 3days for three weeks, once the activity is decreased, injections were given weekly once, same dose continued for three more weeks and advised to follow every month to observe the fundus changes in left eye. Every visit patient was examined in detail, BCVA, anterior segment, fundus and also OCT in left eye to see the central macular thickness. Documentation done in every visit, macular changes after intra vitreal injection was documented by taking both horizontal and vertical OCT.
我们报告一例中年女性巨细胞病毒性视网膜炎,以右眼瞳孔区绿色反射为主要表现,主诉为双眼视力下降1个月,在接受HART治疗3年,停药1年半后,经医师建议重新开始治疗,并详细做了病史、全身及眼部检查。行BCVA、裂隙灯检查、间接眼科检查、FFA、B扫描及文献检查,观察右眼眼底进一步变化,左眼玻璃体内注射更昔洛韦以保持视力。患者玻璃体内注射更昔洛韦500微克,每周2次,间隔3天,连续3周,一旦活性下降,每周注射1次,相同剂量再持续3周,建议每月随访观察左眼眼底变化。每次就诊均对患者进行详细检查,包括BCVA、前段、眼底及左眼OCT检查中央黄斑厚度。在每次就诊时,通过水平和垂直OCT记录玻璃体内注射后黄斑的变化。
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引用次数: 0
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IP International Journal of Ocular Oncology and Oculoplasty
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