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Study of Cognitive and Psychiatric Dysfunction in Children with Epilepsy 癫痫患儿认知和精神功能障碍的研究
Pub Date : 2017-08-01 DOI: 10.9790/0853-1606141420
S. Gopu, Usha Rani.H, MuraliRao.G
Back ground: Epilepsy is one of the most physically and psychosocially debilitating chronic illnesses in children. A considerable proportion of children with epilepsy have various other disorders such as ADHD, learning problems, psychosocial difficulties, mental retardation, cerebral palsy or other disabilities. Objective: To assess the prevalence of cognitive and psychosocial dysfunction in children with epilepsy aged 6 14 yrs. Methodology: This is a cross sectional hospital based the study, included 100 children with age group ranging from 6 12 yrs., attending the neurology outpatient services for epilepsy. Cognitive assessment of the children was done by adopting the MISIC (Malins Intelligence Scale for Indian Children) scale. Psychosocial assessment was done by adopting the Developmental Psychopathology Checklist for children (DPCL) Results:Psychosocial dysfunction is observed in 36% of children with epilepsy. The prevalence of various disorders found in epilepsy patients are Learning disorders 30%, Emotional disorders 21%, Conduct disorders 5%, ADHD was 12% and Psychoses was 1%. Conclusion: Cognitive and psychosocial dysfunction are the major comorbid disorders in children with epilepsy.
背景:癫痫是儿童身体和心理社会最衰弱的慢性疾病之一。相当大比例的癫痫患儿患有各种其他疾病,如多动症、学习问题、社会心理困难、智力迟钝、脑瘫或其他残疾。目的:了解6 ~ 14岁癫痫患儿认知和心理社会功能障碍的患病率。方法:这是一项以医院为基础的横断面研究,包括100名儿童,年龄从6岁到12岁不等。参加癫痫的神经病学门诊服务。采用MISIC (Malins Intelligence Scale for Indian children)量表对儿童进行认知能力评估。采用儿童发展精神病理检查表(DPCL)进行心理社会评估。结果:36%的癫痫患儿存在心理社会功能障碍。癫痫患者中各种障碍的患病率为学习障碍30%,情绪障碍21%,行为障碍5%,多动症12%,精神病1%。结论:认知和社会心理功能障碍是癫痫患儿的主要合并症。
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引用次数: 0
Assessment of Lactic Dehydrogenase in Cerebrospinal Fluid to Differentiate Between Structural And Non-Structural Central Nervous System Lesions in Patients with Diminished Level of Consciousness. 评价脑脊液乳酸脱氢酶对意识水平下降患者中枢神经系统结构性和非结构性病变的鉴别价值。
Pub Date : 2017-08-01 DOI: 10.9790/0853-1606142830
Dr.Yogesh Kumar, Dr.Jyoti Prakash Yogi, Dr.Sumanta Banerjee
Although both metabolic and structural abnormalities have devastating effect on the CNS, their treatment approaches and prognoses vary considerably. This study was conducted among 53 patients with diminished level of consciousness and CSF was analyzed for quantitative LDH(IU/L) value. In our study mean CSF-LDH was 25.19 ± 12.92 in patients with non-structural lesion and 86.53 ± 32.09 in patients with structural lesion of brain and difference was statistically highly significant (p<0.001). So CSF-LDH values can be used to differentiate between patients with structural pathology and those with metabolic disturbances.
虽然代谢和结构异常对中枢神经系统都有毁灭性的影响,但它们的治疗方法和预后差异很大。本研究对53例意识水平下降的患者进行脑脊液LDH(IU/L)定量分析。本组脑非结构性病变患者CSF-LDH平均值为25.19±12.92,结构性病变患者CSF-LDH平均值为86.53±32.09,差异有统计学意义(p<0.001)。因此CSF-LDH值可用于区分结构性病理患者和代谢紊乱患者。
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引用次数: 0
Prevalence and Risk Factors of HCV Infection among Haemodialysis Patients at Dialysis Centers in Khartoum State - Sudan 喀土穆州透析中心血液透析患者丙型肝炎病毒感染的流行及危险因素
Pub Date : 2017-07-30 DOI: 10.9790/0853-1603088388
E. Abdalla, K. Shaaban, I. Elkhidir
Hepatitis C virus infection continues to be a major public health problem warranting high priority efforts for control and treatment. Hepatitis C virus infection is a major health problem among dialysis patients in developing countries. This study was conducted to measure the prevalence of HCV and to identify the possible risk factors associated with HCV infection among haemodialysis patients at dialysis centers in Khartoum State, Sudan. Methods: A crosssectional facility based study was conducted at ten dialysis centers. A total of 287 subjects were selected. A structured questionnaire was used to collect data on socio-demographic characteristics and risk factors. ELISA was used to test sera for anti-HC. For the analysis, Z-test and Chi-Square test were used. Results: Field workers interviewed ten dialysis centers with a total of 287 study subjects. Sixty out of 287 (20.9%) was found to be anti-HC reactive. The multivariate analysis indicated as risk factors associated to antiHCV positivity the number of blood transfusion received, duration of dialysis treatment, number of units of treatment, history of surgeries, multiple injections and using share razors. P values = (0.0001, 0.0031, 0.0001, 0.0018, 0.0005 and 0.0002) respectively. The study demonstrated the that, duration of dialysis, changing of units of treatment, blood transfusions received, history of surgeries, multiple injections and share razors were considered important risk factors for anti-HC positivity.
丙型肝炎病毒感染仍然是一个主要的公共卫生问题,需要高度优先努力进行控制和治疗。丙型肝炎病毒感染是发展中国家透析患者中的一个主要健康问题。本研究旨在测量苏丹喀土穆州透析中心血液透析患者中丙型肝炎病毒的患病率,并确定与丙型肝炎病毒感染相关的可能危险因素。方法:在10个透析中心进行横断面设施研究。共选取287名受试者。采用结构化问卷收集有关社会人口特征和危险因素的数据。ELISA法检测血清抗- hc。分析采用z检验和卡方检验。结果:现场工作人员采访了10个透析中心,共287名研究对象。287例中有60例(20.9%)具有抗hc反应。多因素分析显示,输血次数、透析治疗持续时间、治疗单位数、手术史、多次注射和使用共用剃须刀是与抗hcv阳性相关的危险因素。P值分别为(0.0001,0.0031,0.0001,0.0018,0.0005,0.0002)。研究表明,透析时间、更换治疗单位、输血次数、手术史、多次注射和共用剃须刀是抗- hc阳性的重要危险因素。
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引用次数: 2
Prevalence of Periodontal Diseases in Orlu Local Government Area of Imo State, Nigeria 尼日利亚伊莫州奥鲁地方政府地区牙周病患病率
Pub Date : 2017-07-01 DOI: 10.9790/0853-160603102107
C. OhamaemeMoses, N. EgwurugwuJude, C. EbuenyiMartha, R. OhamaemeChinyere, C. AzudialuBede, U. EgwurugwuFrances
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引用次数: 1
A Case Of Hodgkin Lymphoma Presenting As Soft Tissue Mass 霍奇金淋巴瘤表现为软组织肿块1例
Pub Date : 2017-07-01 DOI: 10.9790/0853-1607028184
Daniel Ravikumar, C. RajeevThilak, A. Isath, Nikitha Rafeek
The most common early sign of hodgkin lymphoma is a painless swelling (enlargement) of one or more lymph nodes. Lymphoma presenting as a soft tissue mass is relatively uncommon and can easily be confused with a wide variety of inflammatory conditions (neoplasia as well as infectious diseases). Chest wall involvement is uncommon and occurs in about 0.64% of cases . It may represent either an initial manifestation of the disease or a site of recurrence. Here we present a case of Hodgkin lymphoma presenting as soft tissue mass in right side of chest wall without nodal involvement.
霍奇金淋巴瘤最常见的早期征象是一个或多个淋巴结的无痛肿胀(增大)。淋巴瘤表现为软组织肿块是相对罕见的,很容易与各种炎症(肿瘤和感染性疾病)混淆。累及胸壁并不常见,约占0.64%。它可以代表疾病的最初表现,也可以代表复发部位。我们在此报告一例霍奇金淋巴瘤,表现为胸壁右侧软组织肿块,无淋巴结累及。
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引用次数: 0
Evaluation of Albuminand Uric Acid Levels, Catalaseactivity andtotal Antioxidant Statusin Pulmonary Tuberculosis Patientsin Osogbo, Nigeria 尼日利亚Osogbo肺结核患者白蛋白和尿酸水平、过氧化氢酶活性和总抗氧化状态的评估
Pub Date : 2017-07-01 DOI: 10.9790/0853-160701105109
M. Olisekodiaka, C. Igbeneghu, A. Onuegbu, O. Oj, Amah Uk, Okwara Je
Previous reports showed that tuberculosis is associated with increase free radical load and oxidative stress thereby worsening the disease state. An understanding of the antioxidant defense system may be helpful in management and care of the disease. Albumin, Uric acid, catalase activity and total antioxidant status (TAS) were determined in blood samples ofthirty five (35) pulmonary tuberculosis (TB) patients (28 TB and 7 TB+HIV) on drug treatment and thirty (30) apparently healthy controls (Ziehl Neelsen test negative) by standard spectrophotometric methods. Results showed that the means of albumin (30.66mmol/L), catalase activity (50.60 IU/ml) and TAS (2.49 mmol/L) of TB patients were significantly lower than those of the control group (42.50mmol/L, 69.80 IU/ml and 4.86 mmol/L respectively). Mean uric acid (0.76mmol/L) of TB patients was significantly higher than that of (0.58mmol/L) of corresponding control. In addition, means of albumin (31.29mmol/L),uric acid (0.77 mmol/L), catalase activity (50.50 IU/ml) and TAS (2.40mmol/l) of TBgroup did not differ from the respective means ofTB+HIV patients (albumin =28.40mmol/L, uric acid =0.71mmol/L, catalase activity=51.00 IU/ml and TAS =2.81 mmol/L).Means of TAS,albumin and catalase activity of TB+HIV patients were significantly lower than respective means of control but the uric acid of TB+HIV patients (0.71 mmol/L) was higher than that of control (0.58 mmol/L).Significantly low level of plasma albumin, catalase activity and total antioxidant status observed in this study might be due to increased utilization of antioxidants to combat oxidative stress seen in TB and the increase plasma uric acid due to excessive breakdown of cells in pulmonary tuberculosis. Increased antioxidant intake may be essential in the management of TB patients.
以前的报告显示,结核病与自由基负荷增加和氧化应激有关,从而使疾病状态恶化。了解抗氧化防御系统可能有助于疾病的管理和护理。用标准分光光度法测定35例(35例)服药的肺结核患者(28例结核和7例结核+艾滋病)和30例(30例)表面健康对照(Ziehl - Neelsen试验阴性)血液样本中的白蛋白、尿酸、过氧化氢酶活性和总抗氧化状态(TAS)。结果结核患者血清白蛋白平均值(30.66mmol/L)、过氧化氢酶活性平均值(50.60 IU/ml)和TAS平均值(2.49 mmol/L)均显著低于对照组(42.50mmol/L、69.80 IU/ml和4.86 mmol/L)。结核患者的平均尿酸(0.76mmol/L)显著高于相应对照的(0.58mmol/L)。tb组患者白蛋白(31.29mmol/L)、尿酸(0.77 mmol/L)、过氧化氢酶活性(50.50 IU/ml)、TAS (2.40mmol/ L)均值与tb +HIV患者(白蛋白=28.40mmol/L、尿酸=0.71mmol/L、过氧化氢酶活性=51.00 IU/ml、TAS =2.81 mmol/L)均值无显著差异。TB+HIV患者TAS、白蛋白和过氧化氢酶活性均值均显著低于对照组,但TB+HIV患者尿酸均值(0.71 mmol/L)高于对照组(0.58 mmol/L)。本研究中观察到的血浆白蛋白、过氧化氢酶活性和总抗氧化状态的显著低水平可能是由于抗氧化剂的利用增加,以对抗结核病中的氧化应激,以及由于肺结核细胞过度分解而导致的血浆尿酸增加。增加抗氧化剂的摄入可能对结核病患者的治疗至关重要。
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引用次数: 0
A Comparative Evaluation of Different Irrigating System for Removal of Modified Triple Antibiotic Pastefrom Root Canal- An In Vitro Study. 不同灌洗系统去除根管改良三联抗生素糊剂的比较评价-体外研究。
Pub Date : 2017-07-01 DOI: 10.9790/0853-1607021216
Dr. Vishal Changlani, Dr.Vaishali Parekh, Dr Parth Desai, Dr NirajKinariwala, Dr AanchalRana, Dr Pratik Upadhyay
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引用次数: 0
A Study of Prevalence of Urinary Tract Infection among Children with Febrile Seizures in a Tertiary Care Hospital 某三级医院热性惊厥患儿尿路感染患病率调查
Pub Date : 2017-07-01 DOI: 10.9790/0853-1607014648
Dr. P. Srinivas, Dr.Snehalatha Gopu, D. Krishna, Dr.M.Arun Kumar
Background: Febrile seizures and Urinary tract infection (UTI) are the two common morbidities in children which are extensively studied, with prevalence ranging from 2-5% and 1-3% respectively. However, there is paucity of studies combining both morbidities especially in India. Objective: Primary objective of this study is to know the prevalence of Urinary tract infections in children with febrile seizures. Methods: Study includes 100 children with febrile seizures in the age group of 6months to 5 years after excluding neurological and congenital abnormalities. Complete urine examination, urine culture sensitivity and ultrasound abdomen were done in children with suspected UTI. Results: Mean age of presentation of febrile seizures is 34 months.89% children had generalised seizures. 9% cases had UTI with febrile seizures, 21.4% were infants. Conclusion: Urinary tract infection is one of the major etiological cause for febrile seizure in children, more
背景:热性惊厥和尿路感染(UTI)是儿童常见的两种疾病,被广泛研究,患病率分别为2-5%和1-3%。然而,结合这两种发病率的研究很少,特别是在印度。目的:本研究的主要目的是了解热性惊厥患儿尿路感染的患病率。方法:研究对象为100例6个月~ 5岁的发热性惊厥患儿,排除神经和先天性异常。对疑似UTI患儿行全尿检查、尿培养敏感性及腹部超声检查。结果:热性惊厥出现的平均年龄为34个月。89%的儿童有全身性癫痫发作。9%的尿路感染伴发热性惊厥,21.4%为婴儿。结论:尿路感染是儿童热性惊厥的主要病因之一
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引用次数: 1
A Radiological Study of Prevelance of Sinusitis in Children 儿童鼻窦炎发病率的影像学研究
Pub Date : 2017-07-01 DOI: 10.9790/0853-1606123133
Usman Nema, A. Mohd
Introduction: Respiratory tract infections are very common in children in India . However, in the setting of prolonged symptoms suggesting a bacterial infection, radiographic images can lend credence to the diagnosis. Very few reports of the prevalence of sinusitis in children with recurrent respiratory tract symptoms (RRTS) have been reported in India, and, hence, this study was carried out. Methodology : This descriptive study was done at JNMC AMU, a tertiary-care hospital Aligarh,U.P. over a period of 1 year. All children in the age group of 3–15 years who showed RRTS (>3 episodes in 6 months or 6 episodes in 1 year) were included in the study. A total number of 60 children were included in the study. Radiological diagnosis of sinusitis by X-ray PNS and CTscan was done to appreciate the presence of complete opacification, mucosal thickening (at least 4 mm), and air fluid levels . Results and conclusion : Out of 60 children with RRTS 36 cases (60%) were diagnosed as cases of sinusitis radiologically , 24 cases were not diagnosed radiologically.
简介:呼吸道感染在印度儿童中很常见。然而,在长时间的症状提示细菌感染的情况下,x线摄影图像可以增加诊断的可信度。在印度,很少有报道称患有复发性呼吸道症状(RRTS)的儿童中鼻窦炎的流行,因此,进行了这项研究。方法:本描述性研究在JNMC AMU(一家三级保健医院,Aligarh, upp)完成在一年的时间里。所有出现RRTS(6个月>3次发作或1年> 6次发作)的3 - 15岁年龄组儿童均被纳入研究。总共有60名儿童被纳入研究。通过x线PNS和ct扫描对鼻窦炎进行放射学诊断,以确定是否存在完全混浊,粘膜增厚(至少4mm)和空气液水平。结果与结论:60例RRTS患儿放射学诊断为鼻窦炎36例(60%),未诊断24例。
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引用次数: 0
A Study of Impact of Nutrition on Targeted Height among Adolescent Girls 青春期少女营养状况对目标身高影响的研究
Pub Date : 2017-07-01 DOI: 10.9790/0853-1607012732
P. Srinivas, Dr. Shashikala, D. Aparna, Dr.T. pavan
Background: Adolescence is a time of rapid physical growth and second only to the first year after birth during whichchildren gainupto 50%of adult weight and more than 20% of adult height.Somatic growth can be altered by providing optimal nutrition, modifying eating patternsand behaviour. Further it can be a second opportunity to catch up growth with requirements of nutrients being high. The overall nutrition status is very poor among adolescent girls of poor rural groups.So short stature is common. Maternal stunting is a factor of increased risk and it can be attributed to chronic malnutrition. Nutritional intervention during this period can help the adolescent girl to achieve the targeted height to some extent. Objective: To study the impact of nutrition on the height of adolescent girls aged 10-18 years who are short statured due to nutritional deprivation. Method: A total of 128 adolescent girls between ages 10-18 years who were below 2SD height for age and nutritionally deprived were selected and divided into two groups’ controls and cases with 64 in each group. Nutritional intervention in the form of balanced diet with iron supplementation and deworming was given to control group and case group was provided with above diet, iron and in addition micronutrients like zinc,calcium, vitamin D, vitamin A and B-complex vitamins and milk. Both groups were followed for one year with monthly checkups and data analyzed. Results: Nutritional intervention in this study showed a significant increase in height of both groups. Themean height attained in the control group was 6.83cms/year and 7.97cms/year in the test group. When compared with the control group, test group had an additional increase in height of 1.14cms which is statistically significant (p<0.001). Conclusion: Adequate nutrition and micronutrient supplementation of the diet of adolescent girls who are short statured and nutrionally deprived can cause a significant catch up growth in height and improve their general condition.
背景:青春期是一个身体快速生长的时期,仅次于出生后的第一年,儿童体重达到成人的50%,身高超过成人的20%。体细胞生长可以通过提供最佳营养、改变饮食模式和行为来改变。此外,这可能是第二次机会,赶上营养需求很高的生长。农村贫困群体少女的总体营养状况非常差。所以身材矮小是很常见的。产妇发育迟缓是风险增加的一个因素,可归因于慢性营养不良。这一时期的营养干预可以在一定程度上帮助青春期女孩达到目标身高。目的:探讨营养对10 ~ 18岁因营养剥夺而导致的矮小少女身高的影响。方法:选取年龄在10 ~ 18岁、身高低于2SD、营养不良的青春期少女128例,分为对照组和病例两组,每组64例。对照组给予均衡膳食补铁、驱虫等营养干预,病例组给予上述膳食、补铁及补充锌、钙、维生素D、维生素A、b族复合维生素等微量元素和牛奶。两组都进行了为期一年的月度检查和数据分析。结果:通过营养干预,两组儿童的身高均有显著提高。对照组平均身高6.83cm /年,试验组平均身高7.97cm /年。与对照组比较,试验组患者身高增加1.14cm,差异有统计学意义(p<0.001)。结论:营养不良、身材矮小的青春期少女在饮食中补充充足的营养和微量营养素,可显著提高她们的身高,改善她们的全身状况。
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引用次数: 1
期刊
IOSR Journal of Dental and Medical Sciences
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