R. Vaswani, V. Agrawal, K. Khilnani, Manisha Kalher
Purpose:. To compare efficacy of intravitreal Ranibizumab (ivR) and standard laser in patients with visual impairment due to diabetic macular edema (DME) in terms of best corrected visual acuity(BCVA) and central macular thickness(CMT) Design:Single blind hospital based comparative type of randomized follow-up study.: Methods: A total of 80 eyes of 80 patients with centre-involving CSME (both diffuse and focal) were included.Subjects were subjected to treatment with either ivR(3 consecutive monthsand PRN dosing thereafter or modified macular laser therapy (MLT).Treatment outcomes in terms of BCVA and reduction in CMT were measured. Results: There was a statistically significant change in the BCVA compared to baseline in both the groups.The average gain in visual acuity was higher in the ivRgroup.(8.825 ETDRS letters compared with 3.09ETDRS letters in the laser only group at 12 months of follow up.The decrease from the average baseline CMT was higher in the intravitreal antiVEGF group (74.22microns compared with 28.54 microns in the laser only group at Conclusion: Both treatment modalities are effective in treatment of DME. Intravitreal Ranibizumab showed greater efficacy both in terms of final BCVA and reduction in CMT. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any products discussed in this article.
{"title":"Comparison Study of Efficacyinvolving Intravitreal Ranibizumab Versus Standard Laser Mono Therapy in Patients with Visual Impairment Due To Diabetic Macula Edema","authors":"R. Vaswani, V. Agrawal, K. Khilnani, Manisha Kalher","doi":"10.9790/0853-1606125257","DOIUrl":"https://doi.org/10.9790/0853-1606125257","url":null,"abstract":"Purpose:. To compare efficacy of intravitreal Ranibizumab (ivR) and standard laser in patients with visual impairment due to diabetic macular edema (DME) in terms of best corrected visual acuity(BCVA) and central macular thickness(CMT) Design:Single blind hospital based comparative type of randomized follow-up study.: Methods: A total of 80 eyes of 80 patients with centre-involving CSME (both diffuse and focal) were included.Subjects were subjected to treatment with either ivR(3 consecutive monthsand PRN dosing thereafter or modified macular laser therapy (MLT).Treatment outcomes in terms of BCVA and reduction in CMT were measured. Results: There was a statistically significant change in the BCVA compared to baseline in both the groups.The average gain in visual acuity was higher in the ivRgroup.(8.825 ETDRS letters compared with 3.09ETDRS letters in the laser only group at 12 months of follow up.The decrease from the average baseline CMT was higher in the intravitreal antiVEGF group (74.22microns compared with 28.54 microns in the laser only group at Conclusion: Both treatment modalities are effective in treatment of DME. Intravitreal Ranibizumab showed greater efficacy both in terms of final BCVA and reduction in CMT. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any products discussed in this article.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"21 1","pages":"52-57"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74143271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To know the efficacy and adverse events of oralchelation drug deferasirox in multitransfused patients with iron overload i.e beta thalassemia & dyserythropoietic anemia’s who are attending Rajiv Gandhi institute of medical sciences Srikakulam for trans fusions and management Material &methods; Prospective study conducted in dept. of pediatrics at RIMS Srikakulam from august 2014 to December 2016. 25 children are iron overload with multiple transfusions i.e. either betathalassemia major or dyserythropoietic anemia’s were taken for this study. All these were started oral iron chelation therapy i.e., Deferasirox . Results: In this study out of 25 children of iron overload 20 cases are thalassemia In these children 18 are on followup . out of them 1 male & 6 females children are below the age of 9 years. Remaining other are above 10 yrs. 5children presented with dyserythropoietic anemia. The adverse clinical effects are not that much for stoppage of the drug and resolved spontaneously with symptomatic support. Conclusion: The single daily dose oral chelation therapy Deferasirox is effective in beta-thalassemia and dyserythropoietic anemia with minimal adverse effects. Deferasirox appears as an effective oral iron chelator for longterm use.
{"title":"Effects of Oral Chelation Drug Deferasirox in Iron Overload Conditions In Children","authors":"Goriparthy Ratnakumari","doi":"10.9790/0853-1606122930","DOIUrl":"https://doi.org/10.9790/0853-1606122930","url":null,"abstract":"Objective: To know the efficacy and adverse events of oralchelation drug deferasirox in multitransfused patients with iron overload i.e beta thalassemia & dyserythropoietic anemia’s who are attending Rajiv Gandhi institute of medical sciences Srikakulam for trans fusions and management Material &methods; Prospective study conducted in dept. of pediatrics at RIMS Srikakulam from august 2014 to December 2016. 25 children are iron overload with multiple transfusions i.e. either betathalassemia major or dyserythropoietic anemia’s were taken for this study. All these were started oral iron chelation therapy i.e., Deferasirox . Results: In this study out of 25 children of iron overload 20 cases are thalassemia In these children 18 are on followup . out of them 1 male & 6 females children are below the age of 9 years. Remaining other are above 10 yrs. 5children presented with dyserythropoietic anemia. The adverse clinical effects are not that much for stoppage of the drug and resolved spontaneously with symptomatic support. Conclusion: The single daily dose oral chelation therapy Deferasirox is effective in beta-thalassemia and dyserythropoietic anemia with minimal adverse effects. Deferasirox appears as an effective oral iron chelator for longterm use.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"45 1","pages":"29-30"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88165643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Trauma is the leading cause of death among productive age men and continue to be the cause of years of valuable life lost compared with cancer, heart disease, and stroke in combination. Thoracoabdominal trauma has great contribution to mortality of patient due to its anatomical position, contain vital body organs, the most body impact, and oftenly without any skin injury. Early prognosis evaluation of multitrauma patient is difficult. Clinical parameters which reflect patient’s actual condition is required. Procalcitonin (PCT) has a very low level among healty individuals. PCT is known to be reliable biomarker in septic and infection cases dan has accuracy and clinical value to determine diagnosis of sepsis among critically ill patients. PCT as biomarker of SIRS in thoracoabdominal trauma and morbidity caused by SIRS has never been observed. Materials and Methods: The prospective research was done in 4 months. Blood sampels were taken twice. First was taken within 24 hours after trauma. The latter was taken 72 hours after trauma. Inclusion and exclusion criterias were included. Confounding factors were also considered. Results: 53 subjects were collected, 46 male and 7 female. 3 patients were dropped out because they died before the third day. Among 50 subjects, 25 subjects suffered from SIRS with 5 deaths, and 25 subjects were free from SIRS. Patients suffered from SIRS were included in statistical analysis. The results were mean value of PCT level in the first day was 11.178± SD 11.568, which was significantly increased in the third day 13.998 ± SD 14.496 with t value of -4.012, with level of significancy 0.001. The mean PCT level of deceased patients from the first day was 25.98 ± SD 13.47 which was significantly increased in the third day 25.98 ± SD 16.74, with t value of -4.119, with level of significancy 0.05. Pearson correlation test towards increasing levef of PCT and SIRS revealed rcounting was 0.708 with level of significancy 0.000, which means that, the more increasing level of PCT, the chance of SIRS event will also increasing. Conclusion: PCT levels obtained during research reflect high level of inflammation over patients. The higher level of PCT level was associated with the amount of pro inflammatory cytokines relased by the body. This amount of cytokines revealed the extensive tissue damage resulted from trauma. The increasing level of PCT on the third day showed the extension of tissue damage resulted from trauma, which effected in the increasing release of pro inflammatory cytokines. It was concluded that blunt thoracoabdominal trauma patients suffered from SIRS, had increasing level of PCT.
{"title":"Increasing Procalcitonin Level of Blunt Thoracoabdominal Trauma Patients with ISS ≥ 16 in Saiful Anwar General Hospital Malang","authors":"Sinung Wikanadi, T. Huwae","doi":"10.9790/0853-1607016771","DOIUrl":"https://doi.org/10.9790/0853-1607016771","url":null,"abstract":"Background: Trauma is the leading cause of death among productive age men and continue to be the cause of years of valuable life lost compared with cancer, heart disease, and stroke in combination. Thoracoabdominal trauma has great contribution to mortality of patient due to its anatomical position, contain vital body organs, the most body impact, and oftenly without any skin injury. Early prognosis evaluation of multitrauma patient is difficult. Clinical parameters which reflect patient’s actual condition is required. Procalcitonin (PCT) has a very low level among healty individuals. PCT is known to be reliable biomarker in septic and infection cases dan has accuracy and clinical value to determine diagnosis of sepsis among critically ill patients. PCT as biomarker of SIRS in thoracoabdominal trauma and morbidity caused by SIRS has never been observed. Materials and Methods: The prospective research was done in 4 months. Blood sampels were taken twice. First was taken within 24 hours after trauma. The latter was taken 72 hours after trauma. Inclusion and exclusion criterias were included. Confounding factors were also considered. Results: 53 subjects were collected, 46 male and 7 female. 3 patients were dropped out because they died before the third day. Among 50 subjects, 25 subjects suffered from SIRS with 5 deaths, and 25 subjects were free from SIRS. Patients suffered from SIRS were included in statistical analysis. The results were mean value of PCT level in the first day was 11.178± SD 11.568, which was significantly increased in the third day 13.998 ± SD 14.496 with t value of -4.012, with level of significancy 0.001. The mean PCT level of deceased patients from the first day was 25.98 ± SD 13.47 which was significantly increased in the third day 25.98 ± SD 16.74, with t value of -4.119, with level of significancy 0.05. Pearson correlation test towards increasing levef of PCT and SIRS revealed rcounting was 0.708 with level of significancy 0.000, which means that, the more increasing level of PCT, the chance of SIRS event will also increasing. Conclusion: PCT levels obtained during research reflect high level of inflammation over patients. The higher level of PCT level was associated with the amount of pro inflammatory cytokines relased by the body. This amount of cytokines revealed the extensive tissue damage resulted from trauma. The increasing level of PCT on the third day showed the extension of tissue damage resulted from trauma, which effected in the increasing release of pro inflammatory cytokines. It was concluded that blunt thoracoabdominal trauma patients suffered from SIRS, had increasing level of PCT.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"21 1","pages":"67-71"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84818869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dental impressions often carry microorganisms that may cause cross infection from patients to dental staff. The control of cross infection is an imperative issue when dealing with dental impression materials in Dentistry and the lack of procedures for its control is currently a real problem. The aim of this study was to evaluate the antimicrobial effectiveness of 0,5% sodium hypochlorite and 2% glutaraldehyde immersion of alginate.Thirty edentulous patients were selected for the present study. Maxillary ridge impressions were taken out in 30 patients with alginate and was randomly divided into two groups containing 15 impressions each group, each impression was swabbed and incubated on nutrient agar culture media. This constituted the control group. Group A impressions were immersed in 0.5% sodium hypochlorite and group B impressions were immersed in 2%glutaraldehyde. All impressions received the similar disinfectant treatment. After 10 minutes the impressions were reswabbed and incubated for 24 hours and microbial colony count was carried out. It was observed that 2% glutaraldehydeis more efficient in reducing the number of bacterial colony count compared to 0.5% sodium hypochlorite.2% glutaraldehyde eliminated 46.74% of bacteria colony count while 0.5% sodium hypochlorite eliminated 43.33% of bacteria colony count. Dental impression materials can act as vectors transmitting a significant amount of microorganisms. It was concluded that 0.5% sodium hypochlorite and 2% glutaraldehyde was stistically equally effective in reducing the number of bacterial colony count. 2% glutaraldehyde was found to be marginally more effective than 0.5% sodium hypochlorite on alginate impressions.
{"title":"Antimicrobial Efficacy of Immersion 0.5% Sodium Hypochlorite And 2% Glutaraldehyde Disinfectants on Alginate Impressions","authors":"Eddy Dahar, J. Kaur","doi":"10.9790/0853-1606131114","DOIUrl":"https://doi.org/10.9790/0853-1606131114","url":null,"abstract":"Dental impressions often carry microorganisms that may cause cross infection from patients to dental staff. The control of cross infection is an imperative issue when dealing with dental impression materials in Dentistry and the lack of procedures for its control is currently a real problem. The aim of this study was to evaluate the antimicrobial effectiveness of 0,5% sodium hypochlorite and 2% glutaraldehyde immersion of alginate.Thirty edentulous patients were selected for the present study. Maxillary ridge impressions were taken out in 30 patients with alginate and was randomly divided into two groups containing 15 impressions each group, each impression was swabbed and incubated on nutrient agar culture media. This constituted the control group. Group A impressions were immersed in 0.5% sodium hypochlorite and group B impressions were immersed in 2%glutaraldehyde. All impressions received the similar disinfectant treatment. After 10 minutes the impressions were reswabbed and incubated for 24 hours and microbial colony count was carried out. It was observed that 2% glutaraldehydeis more efficient in reducing the number of bacterial colony count compared to 0.5% sodium hypochlorite.2% glutaraldehyde eliminated 46.74% of bacteria colony count while 0.5% sodium hypochlorite eliminated 43.33% of bacteria colony count. Dental impression materials can act as vectors transmitting a significant amount of microorganisms. It was concluded that 0.5% sodium hypochlorite and 2% glutaraldehyde was stistically equally effective in reducing the number of bacterial colony count. 2% glutaraldehyde was found to be marginally more effective than 0.5% sodium hypochlorite on alginate impressions.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"67 1","pages":"11-14"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90731762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dr.B. Narahari, Dr.C. Chandramohan, Dr.M. Ranjeet, K. Sreenivas
Background: Poisoning is a very common emergency in the pediatric department which causes a lot of worry and anxiety to parents as well as doctors. The incidence type and nature of poisoning is influenced by various factors hence a study was proposed on poisoning to form treatment protocols. Aims and Objectives: To conduct a study on Accidental poisoning in children and to find out commonest poisoning, its route, type of poison with clinical features, mortality, and outcome of cases of accidental poisoning. Study design: Prospective observational study of all cases of poisoning. Material And Methods: Hundred children who were below 12 years of age who had accidental poisoning admitted in pediatric emergency department at Niloufer Hospital were taken for study from 2016 November to 2017 June. Results: out of 100 cases studied oral route (89%) parenteral route (11%), age distribution below 5 years were (67.6%), urban cases (71%) ,rural cases (29%) , time since poisoning within 6hours(81% ), after 6 hours of exposure(19%), commonest clinical features involved is vomiting (40%), kerosene was commonest type of poisoning with (44%), mortality was (2%). Conclusions: The oral route of poisoning was more common than parenteral route, commonest age group was toddlers, most of the patients were from urban population, most common poison being kerosene. The time taken to transfer patient from rural area was twice that of urban area, duration of stay for most patients was between 1 to 2 days, mortality in the study was (2%).
{"title":"Accidental Poisoning in Children – At Tertiary Care Unit","authors":"Dr.B. Narahari, Dr.C. Chandramohan, Dr.M. Ranjeet, K. Sreenivas","doi":"10.9790/0853-1606126165","DOIUrl":"https://doi.org/10.9790/0853-1606126165","url":null,"abstract":"Background: Poisoning is a very common emergency in the pediatric department which causes a lot of worry and anxiety to parents as well as doctors. The incidence type and nature of poisoning is influenced by various factors hence a study was proposed on poisoning to form treatment protocols. Aims and Objectives: To conduct a study on Accidental poisoning in children and to find out commonest poisoning, its route, type of poison with clinical features, mortality, and outcome of cases of accidental poisoning. Study design: Prospective observational study of all cases of poisoning. Material And Methods: Hundred children who were below 12 years of age who had accidental poisoning admitted in pediatric emergency department at Niloufer Hospital were taken for study from 2016 November to 2017 June. Results: out of 100 cases studied oral route (89%) parenteral route (11%), age distribution below 5 years were (67.6%), urban cases (71%) ,rural cases (29%) , time since poisoning within 6hours(81% ), after 6 hours of exposure(19%), commonest clinical features involved is vomiting (40%), kerosene was commonest type of poisoning with (44%), mortality was (2%). Conclusions: The oral route of poisoning was more common than parenteral route, commonest age group was toddlers, most of the patients were from urban population, most common poison being kerosene. The time taken to transfer patient from rural area was twice that of urban area, duration of stay for most patients was between 1 to 2 days, mortality in the study was (2%).","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"5 8 1","pages":"61-65"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90348426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.9790/0853-160701120127
Dr. M. Shahidul Islam
Copy number changes, also called chromosome gains or losses in the DNA content, have drawn recent attention in advancement of cancer research. Array CGH (Comparative Genomic Hybridization) is a molecular-cytogenetic method for genomewide screening for such loss and gain regions referring to genetic alterations. In this article, we present a simple but very effective method to uncover the locations of copy number changes through the use of modified maximal overlap discrete wavelet transform (MODWT) devised with some threshold approach. Implementations to simulated data having autocorrelation structure as well as to real CGH array confirm the excellent performance of this procedure.
{"title":"Change Detection and Application to CGH Arrays","authors":"Dr. M. Shahidul Islam","doi":"10.9790/0853-160701120127","DOIUrl":"https://doi.org/10.9790/0853-160701120127","url":null,"abstract":"Copy number changes, also called chromosome gains or losses in the DNA content, have drawn recent attention in advancement of cancer research. Array CGH (Comparative Genomic Hybridization) is a molecular-cytogenetic method for genomewide screening for such loss and gain regions referring to genetic alterations. In this article, we present a simple but very effective method to uncover the locations of copy number changes through the use of modified maximal overlap discrete wavelet transform (MODWT) devised with some threshold approach. Implementations to simulated data having autocorrelation structure as well as to real CGH array confirm the excellent performance of this procedure.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"2672 1","pages":"120-127"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75834547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The study “postprandial hypertriglyceridemia as a risk factor for macro vascular complications in type 2 diabetes mellitus” was a case control study conducted on patients visiting the out patient department of Government Rajaji Hospital, Madurai. Sixty eight patients with type 2 diabetes mellitus and 22 healthy controls were included in the study. Selected patients and controls underwent clinical and biochemical evaluation including blood sugar, lipid profile and cardiac function to detect the presence of macro vascular complications of diabetes. Selected patients and subjects were subjected to a high fat meal and plasma triglycerides were measured two and four hours after fat challenge. It was observed that post load hypertriglyceridemia correlated better than fasting triglycerides in patients with macro vascular complications. It was also observed that persistent postprandial hypertriglyceridemia was observed in diabetic patients with complications.
{"title":"Post Prandial Hypertriglyceridemia as a Risk Factor for Macro Vascular Complications in Type 2 Diabetes Mellitus","authors":"D. Ranganathan, Dr.Subbiah Eagappan","doi":"10.9790/0853-1607025762","DOIUrl":"https://doi.org/10.9790/0853-1607025762","url":null,"abstract":"The study “postprandial hypertriglyceridemia as a risk factor for \u0000macro vascular complications in type 2 diabetes mellitus” was a case \u0000control study conducted on patients visiting the out patient department of \u0000Government Rajaji Hospital, Madurai. Sixty eight patients with type 2 \u0000diabetes mellitus and 22 healthy controls were included in the study. \u0000Selected patients and controls underwent clinical and biochemical \u0000evaluation including blood sugar, lipid profile and cardiac function to \u0000detect the presence of macro vascular complications of diabetes. Selected \u0000patients and subjects were subjected to a high fat meal and plasma \u0000triglycerides were measured two and four hours after fat challenge. It was \u0000observed that post load hypertriglyceridemia correlated better than fasting \u0000triglycerides in patients with macro vascular complications. It was also \u0000observed that persistent postprandial hypertriglyceridemia was observed \u0000in diabetic patients with complications.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"16 1","pages":"57-62"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83442136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tapati Mondal, Nilay Mandal, P. Mukherjee, Purushottam Kumar, C. Chattopadhyay
{"title":"A Clinico-Epidemiological Study on Opportunistic Fungal Infection In HIV Patients And Its Corroboration With CD4 Cell Count","authors":"Tapati Mondal, Nilay Mandal, P. Mukherjee, Purushottam Kumar, C. Chattopadhyay","doi":"10.9790/0853-1606135659","DOIUrl":"https://doi.org/10.9790/0853-1606135659","url":null,"abstract":"","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"65 1","pages":"56-59"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79581968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.9790/0853-160603160165
Malaz Mohammed Ali Omer Ahmed
Patients with sickle cell disease (SCD) may have frequent episodes of abdominal pain and/or fever of uncertain cause. While many of these episodes represent the possibility of complications; Computed tomography (CT) was used to evaluate 67 Saudi Arabian patients with SCD .In 67 of the patients; the liver was affected in 59 patients, lungs in 56 patients, kidneys in 55 and gall bladder in 22 patients and pancreas in 5 cases. Spleen abnormalities were found to be Splenomegaly, cyst, abscess, infarction, Splenomegaly with cyst and Splenomegaly with abscess where the patient’s age and SC type were considered. Hepatic abnormalities including focal necrosis, Hepatomegaly, abscess, cyst; infarction as well; Cholelithiasis, gall stones and dilated common bile duct and acute pancreatitis were also considered as an important manifestation of SCD. Renal abnormalities were found to be papillary necrosis, renal abscess, Stones with hydronephrosis, renal vein thrombosis, renal failure and renal infarction. Lungs CT manifestations were found to be pleural effusion, pneumonia, atelectasis, ground glass nodules, consolidation, fibrosis, Lung abscess. The episodes were increased by increasing of the children age at different SCD. Computed tomography (CT) has been shown to be an excellent modality for efficient and multisystemic evaluation of the abdomen and chest in these patients.
{"title":"Sickle cell disease: chest and abdominal manifestation-A CT based study","authors":"Malaz Mohammed Ali Omer Ahmed","doi":"10.9790/0853-160603160165","DOIUrl":"https://doi.org/10.9790/0853-160603160165","url":null,"abstract":"Patients with sickle cell disease (SCD) may have frequent episodes of abdominal pain and/or fever of uncertain cause. While many of these episodes represent the possibility of complications; Computed tomography (CT) was used to evaluate 67 Saudi Arabian patients with SCD .In 67 of the patients; the liver was affected in 59 patients, lungs in 56 patients, kidneys in 55 and gall bladder in 22 patients and pancreas in 5 cases. Spleen abnormalities were found to be Splenomegaly, cyst, abscess, infarction, Splenomegaly with cyst and Splenomegaly with abscess where the patient’s age and SC type were considered. Hepatic abnormalities including focal necrosis, Hepatomegaly, abscess, cyst; infarction as well; Cholelithiasis, gall stones and dilated common bile duct and acute pancreatitis were also considered as an important manifestation of SCD. Renal abnormalities were found to be papillary necrosis, renal abscess, Stones with hydronephrosis, renal vein thrombosis, renal failure and renal infarction. Lungs CT manifestations were found to be pleural effusion, pneumonia, atelectasis, ground glass nodules, consolidation, fibrosis, Lung abscess. The episodes were increased by increasing of the children age at different SCD. Computed tomography (CT) has been shown to be an excellent modality for efficient and multisystemic evaluation of the abdomen and chest in these patients.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"20 1","pages":"160-165"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74446277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The pathogenesis of neuropathy in type 2 diabetes mellitus is multifactorial. This study is aimed to assess any association of dyslipidemias with peripheral neuropathy in type 2 diabetes mellitus. It also reveals any difference in lipid profile between asymptomatic (without symptoms of peripheral neuropathy) and symptomatic (with symptoms of peripheral neuropathy) subjects of diabetes mellitus.
{"title":"Comparison of Serum Lipid Profile in Diabetics With and Without Symptoms of Peripheral Neuropathy","authors":"G. Suneetha., A. SatyanarayanaPrasad.","doi":"10.9790/0853-1607021721","DOIUrl":"https://doi.org/10.9790/0853-1607021721","url":null,"abstract":"The pathogenesis of neuropathy in type 2 diabetes mellitus is multifactorial. This study is aimed to assess any association of dyslipidemias with peripheral neuropathy in type 2 diabetes mellitus. It also reveals any difference in lipid profile between asymptomatic (without symptoms of peripheral neuropathy) and symptomatic (with symptoms of peripheral neuropathy) subjects of diabetes mellitus.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"44 1","pages":"17-21"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74724704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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