Kharche Jyoti, P. Vikrant, Yadav Pawan, Quazi Kashifuddin, K. Amit
Bardet-Biedl syndrome (BBS) is a rare, genetic disorder (autosomal recessive ciliopathy) with involvement of multiple systems and wide spectrum of clinical features. Characteristic features of this disorder are cone-rod dystrophy, postaxial polydactyly, truncal obesity, kidney abnormalities and learning difficulties. It may also be associated with diminished size and decreased function of the testes in males (hypogonadism) and complex genitourinary abnormalities in females. Bardet-Biedl syndrome is inherited mostly as an autosomal recessive trait. It affects males and females equally. This syndrome is usually diagnosed in childhood based upon thorough clinical evaluation and detection of characteristic findings (e.g., visual problems due to retinal dystrophy, obesity, polydactyly). Genetic testing may assist in diagnosing the disorder in selected cases (e.g., individuals with certain BBS1 and BBS10 gene mutations). The treatment of Bardet-Biedl syndrome is directed toward the specific symptoms that are apparent in each individual. Treatment may require the co-ordinated efforts of a team of specialists.We present a case of 28yrs female patient with Bardet-Biedl syndrome who presented in out-patient department with episodes of loose motions, vague abdominal pain,swelling all over body and decreased urine outut. She had history of obesity, diminished vision and polydactyly. On investigations she had anemia of chronic disease, deranged renal fuction tests and retinitis pigmentosa.
{"title":"Bardet-Biedl Syndrome- A Rare Case Presenatation In Marathwada Region Of India","authors":"Kharche Jyoti, P. Vikrant, Yadav Pawan, Quazi Kashifuddin, K. Amit","doi":"10.9790/0853-1607014952","DOIUrl":"https://doi.org/10.9790/0853-1607014952","url":null,"abstract":"Bardet-Biedl syndrome (BBS) is a rare, genetic disorder (autosomal recessive ciliopathy) with involvement of multiple systems and wide spectrum of clinical features. Characteristic features of this disorder are cone-rod dystrophy, postaxial polydactyly, truncal obesity, kidney abnormalities and learning difficulties. It may also be associated with diminished size and decreased function of the testes in males (hypogonadism) and complex genitourinary abnormalities in females. Bardet-Biedl syndrome is inherited mostly as an autosomal recessive trait. It affects males and females equally. This syndrome is usually diagnosed in childhood based upon thorough clinical evaluation and detection of characteristic findings (e.g., visual problems due to retinal dystrophy, obesity, polydactyly). Genetic testing may assist in diagnosing the disorder in selected cases (e.g., individuals with certain BBS1 and BBS10 gene mutations). The treatment of Bardet-Biedl syndrome is directed toward the specific symptoms that are apparent in each individual. Treatment may require the co-ordinated efforts of a team of specialists.We present a case of 28yrs female patient with Bardet-Biedl syndrome who presented in out-patient department with episodes of loose motions, vague abdominal pain,swelling all over body and decreased urine outut. She had history of obesity, diminished vision and polydactyly. On investigations she had anemia of chronic disease, deranged renal fuction tests and retinitis pigmentosa.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"23 1","pages":"49-52"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76089313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. S. Gugwad, Savita Chakote, DrSharanbasappa CNagaral, DrGoslaShrinivas Reddy
{"title":"Titanium asa Biomaterial For Dental ImplantsandIts Corrosion Rate- An Animal Stud","authors":"R. S. Gugwad, Savita Chakote, DrSharanbasappa CNagaral, DrGoslaShrinivas Reddy","doi":"10.9790/0853-1607024045","DOIUrl":"https://doi.org/10.9790/0853-1607024045","url":null,"abstract":"","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"51 1","pages":"40-45"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86803205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aims and objectives: 1. To assess the beliefs and perceptions about cancer and its treatment among cancer patients. 2. To find out the care-seeking behaviour of cancer patients. 3. To determine socio-demographic correlation. Materials and methods: This is a cross sectional observational study over one year (April 2016 – April 2017) in the Department of Radiotherapy, Bankura Sammilani Medical College, a tertiary care, teaching hospital in Bankura. Total 100 patients over 18 years of age were included in the study. Date were analysed in Excel sheet and tests of significance were applied wherever applicable by SPSS 20 ® . Results: Present study revealed Male: Female ratio (1: 1) with majority of the patients from 46-60 years of age group (44%) and below poverty line (71%). About 64% patients were unaware of their disease. Seventy three percent patients believed that cancer is curable, 21% patients believed that it is preventable. Among them 98% patients had no family history of cancer. No statistical significance were found in association of education status and belief on preventability, contagiousness, knowledge of consumption of tobacco with cancer. However belief on early death in cancer with education status and false belief on positive outcome in cancer (Male: 62% and Female: 38%) in male and female patients were found to be statistically significant. Conclusion: The study revealed some of the beliefs and perceptions prevalent among the cancer patients. Most of them were unaware about the diagnosis of their illness as cancer. Some of them still believe irreligious activity, supernatural powers as risk factors of cancers and rituals, worshipping, exorcism, repenting for sins as curative. Education was found to be an important issue in these beliefs and perceptions as these were more found in persons with lower educational qualification. Influence was not affected by economic condition.
{"title":"Beliefs and Perceptions about Cancers among Patients Attending Radiotherapy Out Patient Department of a Tertiary Care Hospital","authors":"P. Jana","doi":"10.9790/0853-1606134655","DOIUrl":"https://doi.org/10.9790/0853-1606134655","url":null,"abstract":"Aims and objectives: 1. To assess the beliefs and perceptions about cancer and its treatment among cancer patients. 2. To find out the care-seeking behaviour of cancer patients. 3. To determine socio-demographic correlation. Materials and methods: This is a cross sectional observational study over one year (April 2016 – April 2017) in the Department of Radiotherapy, Bankura Sammilani Medical College, a tertiary care, teaching hospital in Bankura. Total 100 patients over 18 years of age were included in the study. Date were analysed in Excel sheet and tests of significance were applied wherever applicable by SPSS 20 ® . Results: Present study revealed Male: Female ratio (1: 1) with majority of the patients from 46-60 years of age group (44%) and below poverty line (71%). About 64% patients were unaware of their disease. Seventy three percent patients believed that cancer is curable, 21% patients believed that it is preventable. Among them 98% patients had no family history of cancer. No statistical significance were found in association of education status and belief on preventability, contagiousness, knowledge of consumption of tobacco with cancer. However belief on early death in cancer with education status and false belief on positive outcome in cancer (Male: 62% and Female: 38%) in male and female patients were found to be statistically significant. Conclusion: The study revealed some of the beliefs and perceptions prevalent among the cancer patients. Most of them were unaware about the diagnosis of their illness as cancer. Some of them still believe irreligious activity, supernatural powers as risk factors of cancers and rituals, worshipping, exorcism, repenting for sins as curative. Education was found to be an important issue in these beliefs and perceptions as these were more found in persons with lower educational qualification. Influence was not affected by economic condition.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"33 1","pages":"46-55"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89550052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The possibility of postsurgical hypothyroidism after hemithyroidectomy is an underappreciated complication . We intended to evaluate the incidence of development of hypothyroidism after hemithyroidectomy and to analyze the relationship of posthemithyroidectomy hypothyroidism with preoperative biochemical parameters(preoperative TSH,Thyroid antibody levels) and postoperative histopathological findings. From November 2010 to May 2011, 60 cases of hemithyroidectomized patients were analyzed. Postoperative hypothyroidism developed in 19 patients(31.66%). Preoperative TSH value was significantly higher in the hypothyroid group (2.68 μIU/ml) compared to the euthyroid group (1.39 μIU/ml). Elevated thyroid antibody(TAA) levels were observed in 53% of patients developing postoperative hypothyroidism as compared to 12% of patients who remain euthyroid (p = 0.00077) . Moreover, patients with a higher grade of lymphocytic infiltration were found to have a higher probability of developing hypothyroidism. In addition, our findings support the recommendation for regular serum TSH follow-up at least for 6 months after hemithyroidectomy.
{"title":"Prediction of Hypothyroidism after Hemithyroidectomy: A Biochemical and Pathological Analysis.","authors":"Abhinav Rathi, D. Sharma, B. Prasad","doi":"10.9790/0853-1606116163","DOIUrl":"https://doi.org/10.9790/0853-1606116163","url":null,"abstract":"The possibility of postsurgical hypothyroidism after hemithyroidectomy is an underappreciated complication . We intended to evaluate the incidence of development of hypothyroidism after hemithyroidectomy and to analyze the relationship of posthemithyroidectomy hypothyroidism with preoperative biochemical parameters(preoperative TSH,Thyroid antibody levels) and postoperative histopathological findings. From November 2010 to May 2011, 60 cases of hemithyroidectomized patients were analyzed. Postoperative hypothyroidism developed in 19 patients(31.66%). Preoperative TSH value was significantly higher in the hypothyroid group (2.68 μIU/ml) compared to the euthyroid group (1.39 μIU/ml). Elevated thyroid antibody(TAA) levels were observed in 53% of patients developing postoperative hypothyroidism as compared to 12% of patients who remain euthyroid (p = 0.00077) . Moreover, patients with a higher grade of lymphocytic infiltration were found to have a higher probability of developing hypothyroidism. In addition, our findings support the recommendation for regular serum TSH follow-up at least for 6 months after hemithyroidectomy.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"1 1","pages":"61-63"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76559528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.9790/0853-160701110115
Balasubramanian V MCh, Sridevi, S. Vathulru, Asish Jakhetiya
Background: Arm lymphatics draining through the axilla are frequently disrupted during surgery for carcinoma breast leading to lymphedema. Techniques for differential identification of arm lymphatics might enable their preservation, and probable reduction in lymphedema. Aims: To evaluate the efficacy and oncological safety of reverse axillary mapping (RAM) in patients with early stage breast carcinoma and to correlate with post operative pathological nodal status. Methods and Material: It is a prospective pilot study, conducted at a tertiary care cancer speciality hospital, among patients with early stage breast cancer ( cT1/T2 cN1M0) planned for straight surgery, consenting to be part of the study. Patients were subjected to injection of blue dye (total 1 ml) at the time of surgery. During axillary dissection, lymphnodes taking up blue dye, were identified, dissected out and sent separately for pathological assessment . Results: RAM technique with blue dye identified arm lymphatic in ipsilateral axilla in 72.22%. Blue lymph nodes were identified in 61.11%. Postoperatively 13 out of 18 patients were staged as pN0, two as pN1, and three as pN3. RAM identified arm lymph nodes were free of diseases in all the patients with pN0,pN1 patients, only one of the three pN3 patients showed metastatic involvement . ( all pN3 patients could be identified as suspicious of having high nodal disease intraoperatively) Conclusions: Reverse axillary mapping can be used to identify the arm lymphatics in the ipsilateral axilla and these nodes are found to be free of metastatic disease in early stage breast cancer. I. Background Lymphatic drainage of the breast and ipsilateral upper limb is through the axilla. Majority of the cases, the two lymphatic pathways are different[1] Technique, that can differentially identify the upper limb lymphatic in the axilla can help preventing disruption of arm lymphatics at the time of axillary dissection for breast cancer. This may help reduce lymphedema, the most significant morbidity associated with surgical management of breast cancer. Reverse axillary mapping (RAM) technique, is a recent development, aimed at identifying the arm lymphatics in axilla at the time of axillary surgery for carcinoma breast. Various techniques have been described for the same using blue dye ,radioisotope or fluorescence imaging[2–5]. Although arm and breast lymphatics have been postulated to have differential drainage crossover has been documented in 2-18% [1,5–7] with pathologically proven involvement of nodes draining the arm by metastatic carcinoma from breast in 043%[5,7–11]. Most common complication associated with this procedure has been local tattoing lasting from few weeks to as long as 6 months. We aim to evaluate the efficacy of identification of arm lymphatic using low volume methylene blue injection (1-1.5 ml) and the degree of involvement of RAM identified nodes by metastatic disease among women with early stage breast cancer. II. Methods
{"title":"“Reverse axillary mapping in early stage breast cancer Is it oncologically safe? A feasibity study","authors":"Balasubramanian V MCh, Sridevi, S. Vathulru, Asish Jakhetiya","doi":"10.9790/0853-160701110115","DOIUrl":"https://doi.org/10.9790/0853-160701110115","url":null,"abstract":"Background: Arm lymphatics draining through the axilla are frequently disrupted during surgery for carcinoma breast leading to lymphedema. Techniques for differential identification of arm lymphatics might enable their preservation, and probable reduction in lymphedema. Aims: To evaluate the efficacy and oncological safety of reverse axillary mapping (RAM) in patients with early stage breast carcinoma and to correlate with post operative pathological nodal status. Methods and Material: It is a prospective pilot study, conducted at a tertiary care cancer speciality hospital, among patients with early stage breast cancer ( cT1/T2 cN1M0) planned for straight surgery, consenting to be part of the study. Patients were subjected to injection of blue dye (total 1 ml) at the time of surgery. During axillary dissection, lymphnodes taking up blue dye, were identified, dissected out and sent separately for pathological assessment . Results: RAM technique with blue dye identified arm lymphatic in ipsilateral axilla in 72.22%. Blue lymph nodes were identified in 61.11%. Postoperatively 13 out of 18 patients were staged as pN0, two as pN1, and three as pN3. RAM identified arm lymph nodes were free of diseases in all the patients with pN0,pN1 patients, only one of the three pN3 patients showed metastatic involvement . ( all pN3 patients could be identified as suspicious of having high nodal disease intraoperatively) Conclusions: Reverse axillary mapping can be used to identify the arm lymphatics in the ipsilateral axilla and these nodes are found to be free of metastatic disease in early stage breast cancer. I. Background Lymphatic drainage of the breast and ipsilateral upper limb is through the axilla. Majority of the cases, the two lymphatic pathways are different[1] Technique, that can differentially identify the upper limb lymphatic in the axilla can help preventing disruption of arm lymphatics at the time of axillary dissection for breast cancer. This may help reduce lymphedema, the most significant morbidity associated with surgical management of breast cancer. Reverse axillary mapping (RAM) technique, is a recent development, aimed at identifying the arm lymphatics in axilla at the time of axillary surgery for carcinoma breast. Various techniques have been described for the same using blue dye ,radioisotope or fluorescence imaging[2–5]. Although arm and breast lymphatics have been postulated to have differential drainage crossover has been documented in 2-18% [1,5–7] with pathologically proven involvement of nodes draining the arm by metastatic carcinoma from breast in 043%[5,7–11]. Most common complication associated with this procedure has been local tattoing lasting from few weeks to as long as 6 months. We aim to evaluate the efficacy of identification of arm lymphatic using low volume methylene blue injection (1-1.5 ml) and the degree of involvement of RAM identified nodes by metastatic disease among women with early stage breast cancer. II. Methods","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"65 1","pages":"110-115"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72801113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim and objectives: Mandibular foramen is leading to mandibular canal through which inferior alveolar nerve and vessels transmit and supply the teeth of lower jaw. Inferior alveolar nerve block is a common local anaesthetic technique, prior to dental surgeries of lower jaw. Hence a precise anatomical knowledge is highly essential to locate the mandibular foramen for this nerve block. Materials and method: 65 adult edentulous dry human mandibles of Southern Odisha of unknown age and sex were taken for descriptive study. Distance of mandibular foramen from mandibular notch, anterior border, posterior border and angle of mandible were measured by slide calliper, data were tabulated and analysed statistically. Results: The mean distance of mandublar foramen to anterior border was 17.21mm in right side and 17.0 mm in left side, to posterior border 16.1mm in right side and 16.0mm in left side, to the floor of the mandibular notch 20.8mm in right side and 21.3 mm in left side. and to gonium 21.31mm in right side and 20.34mm in left side were obtained. Conclusion: Localisation of mandibular foramen is an important pre-requisite prior to inferior alveolar nerve block during any mandibular surgery. Keyword: Anterior border, mandibular angle, mandibular foramen, ramus of mandible, slide calliper
{"title":"Location of the Mandibular Foramen in Dry Mandibles: A Study in Southern Odisha","authors":"R. Sahu, Suchitra Panigrahi, B. Rath, S. Rath","doi":"10.9790/0853-1606133235","DOIUrl":"https://doi.org/10.9790/0853-1606133235","url":null,"abstract":"Aim and objectives: Mandibular foramen is leading to mandibular canal through which inferior alveolar nerve and vessels transmit and supply the teeth of lower jaw. Inferior alveolar nerve block is a common local anaesthetic technique, prior to dental surgeries of lower jaw. Hence a precise anatomical knowledge is highly essential to locate the mandibular foramen for this nerve block. Materials and method: 65 adult edentulous dry human mandibles of Southern Odisha of unknown age and sex were taken for descriptive study. Distance of mandibular foramen from mandibular notch, anterior border, posterior border and angle of mandible were measured by slide calliper, data were tabulated and analysed statistically. Results: The mean distance of mandublar foramen to anterior border was 17.21mm in right side and 17.0 mm in left side, to posterior border 16.1mm in right side and 16.0mm in left side, to the floor of the mandibular notch 20.8mm in right side and 21.3 mm in left side. and to gonium 21.31mm in right side and 20.34mm in left side were obtained. Conclusion: Localisation of mandibular foramen is an important pre-requisite prior to inferior alveolar nerve block during any mandibular surgery. Keyword: Anterior border, mandibular angle, mandibular foramen, ramus of mandible, slide calliper","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"19 1","pages":"32-35"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85321956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Hepatic encephalopathy is a reversible neuro-psychiatric syndrome occurring in majority of patients with decompensated chronic liver disease(CLD). Prognosis of Hepatic encephalopathy (HE) depends upon past h/o hematemesis/ melena and HE but not related to the aetiology of CLD. Rifaximin and lactulose have similar efficacy for treatment of acute HE . Purpose of this study is to compare the effectiveness of 3 modes of treatment for 7 days in terms of clinical improvement / deterioration who have or have not past h/o hematemesis/ melenaand or HE. Material and methods: After ethical clearance and consent from patient parties, 90 patients of HE of any cause and grade with or without past h/o hematemesis/melena and or HE, were categorise into different grades according to West Haven criteria and randomised to treat for 7 days with divided doses by either rifaximin 30 patients, lactulose 30 patients , rifaximin plus lactulose 30 patients. At the end, clinical improvement and deterioration were noticed. Results: Alcoholic CLD (63.33%) was the commonest. Clinical deterioration were commoner in chronic HCV (66.67%) than chronic HBV, alcoholic CLD. Patients with past h/o hematemesis /melena, clinical deterioration and improvement were 26.92% and 73.08% but without such , clinical deterioration and improvement were 2.63% and 97.37% . Patients with past h/o HE , clinical deterioration and improvement were 31.25% and 68.75% but without such past illness, clinical deteriorations and improvements were 0 and 100% . Conclusion: So clinical outcome is better in patients of HE without past h/o HE and hematemesis/melena. Keyword: Hepatic encephalopathy , chronic liver disease ,Rifaximin,Lactulose
{"title":"A Comparative Study to Determine the Outcome of Hepatic Encephalopathy who Have A Past History of Hepatic Encephalopathy And or Upper Gastrointestinal Bleeding Versus Who Have Not Such Using 7 Days Therapy of RifaximinAnd or Lactulose","authors":"Dr.ShyamalKanti Pal, Dr.Subhrajyoti Naskar, Dr.Gauranga Biswas, Dr.Jadab Kumar Jana, Dr.SK. Jeauddin, Dr.Soumitra Kumar Ghosh","doi":"10.9790/0853-1607025054","DOIUrl":"https://doi.org/10.9790/0853-1607025054","url":null,"abstract":"Introduction: Hepatic encephalopathy is a reversible neuro-psychiatric syndrome occurring in majority of patients with decompensated chronic liver disease(CLD). Prognosis of Hepatic encephalopathy (HE) depends upon past h/o hematemesis/ melena and HE but not related to the aetiology of CLD. Rifaximin and lactulose have similar efficacy for treatment of acute HE . Purpose of this study is to compare the effectiveness of 3 modes of treatment for 7 days in terms of clinical improvement / deterioration who have or have not past h/o hematemesis/ melenaand or HE. Material and methods: After ethical clearance and consent from patient parties, 90 patients of HE of any cause and grade with or without past h/o hematemesis/melena and or HE, were categorise into different grades according to West Haven criteria and randomised to treat for 7 days with divided doses by either rifaximin 30 patients, lactulose 30 patients , rifaximin plus lactulose 30 patients. At the end, clinical improvement and deterioration were noticed. Results: Alcoholic CLD (63.33%) was the commonest. Clinical deterioration were commoner in chronic HCV (66.67%) than chronic HBV, alcoholic CLD. Patients with past h/o hematemesis /melena, clinical deterioration and improvement were 26.92% and 73.08% but without such , clinical deterioration and improvement were 2.63% and 97.37% . Patients with past h/o HE , clinical deterioration and improvement were 31.25% and 68.75% but without such past illness, clinical deteriorations and improvements were 0 and 100% . Conclusion: So clinical outcome is better in patients of HE without past h/o HE and hematemesis/melena. Keyword: Hepatic encephalopathy , chronic liver disease ,Rifaximin,Lactulose","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"18 1","pages":"50-54"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89834437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Delayed Presentation of Uterine Perforation Following Unsafe Abortion As Septic Peritonitis","authors":"M. Dr.LogeswariB, VidhyaR, K. Dr.Saraswathi","doi":"10.9790/0853-1606120102","DOIUrl":"https://doi.org/10.9790/0853-1606120102","url":null,"abstract":"","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"28 1","pages":"01-02"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88024607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chronic suppurative otitis media (CSOM) is one of the leading causes of hearing impairment in developing countries. Objectives: are to highlight the high resolution computerized tomography (HRCT) temporal bone findings in chronic middle ear infections with reference to it ’ s extent and complications, as well, the presented common signs, symptoms and the duration impact on the anatomical structures and pathological changes in each part and for both sides. Materials and Methods: Preliminary clinical assessment was obtained for 114 patients diagnosed with CSOM, and then they were referred for a HRCT of temporal bone which was done using multi-detector CT scanner. Results: Of the 114 patients; 63(55.3%) were males and 51(44.7%) were females: Otorrhoea is the most common symptom, and was found in 113 patients constituting (99.1%) followed by Otolegia 69(60.5%) and headache affected 53(46.5%) of the cases. CSOM is more common in low socio-economic status .In ears affected with CSOM, the maximum CT number (Hounsfield) was found to be changed and was significantly affected with increasing patients’ age. Sclerotic changes and soft tissue density increased as the duration of CSOM increased in right and left middle ears significantly (F=5.802, Sig at 0.000), and (F=23.182, Sig at .015) respectively. Partial and complete erosion were detected in both right and left ossicle in the advanced phase of disease, where the ossicle still intact in the early stage , and the correlation is found to be significant with increasing of CSOM duration (F=16.959, Sig 0.000) and (F= 3.673, Sig =0.036)for right and left ossicles respectively. Changes including total and partial opacification, sclerotic changes, soft tissue density, mucosal thickening were the findings detected in both right and left mastoid in HRCT for temporal bone scanning. Conclusions: HRCT of temporal bone is useful in identifying various findings related to the location and extent of disease.
慢性化脓性中耳炎(CSOM)是发展中国家听力损害的主要原因之一。目的:探讨慢性中耳感染的颞骨高分辨率计算机断层扫描(HRCT)表现，包括其程度、并发症、常见体征、症状及持续时间对各部位及双侧解剖结构和病理改变的影响。材料与方法:对114例确诊为CSOM的患者进行初步临床评估，并转介行颞骨HRCT，采用多探头CT扫描。结果:114例患者中;男性63例(55.3%)，女性51例(44.7%)，其中以耳漏最为常见，113例(99.1%)，其次为耳鸣69例(60.5%)，头痛53例(46.5%)。CSOM多见于社会经济地位较低的人群。在患CSOM的耳朵中，最大CT数(Hounsfield)随着患者年龄的增加而改变，并受到显著影响。随着CSOM持续时间的延长，右中耳和左中耳的硬化变化和软组织密度显著增加(F=5.802, Sig = 0.000)， F=23.182, Sig = 0.015)。疾病晚期左右听骨均可见部分和完全糜蚀，早期听骨完好，且与CSOM持续时间的增加相关(F=16.959, Sig 0.000)，与左右听骨的相关性显著(F= 3.673, Sig =0.036)。颞骨HRCT扫描右、左乳突均可见完全或部分浑浊、硬化改变、软组织密度、粘膜增厚等变化。结论:颞骨HRCT在识别与疾病位置和程度相关的各种表现方面是有用的。
{"title":"Findings in CSOM: Our Experience in Sudanese Population-A CT based Study","authors":"Zuhal Y. Hamd, C. Ayad, M. E. Supervisor","doi":"10.9790/0853-1606131523","DOIUrl":"https://doi.org/10.9790/0853-1606131523","url":null,"abstract":"Chronic suppurative otitis media (CSOM) is one of the leading causes of hearing impairment in developing countries. Objectives: are to highlight the high resolution computerized tomography (HRCT) temporal bone findings in chronic middle ear infections with reference to it ’ s extent and complications, as well, the presented common signs, symptoms and the duration impact on the anatomical structures and pathological changes in each part and for both sides. Materials and Methods: Preliminary clinical assessment was obtained for 114 patients diagnosed with CSOM, and then they were referred for a HRCT of temporal bone which was done using multi-detector CT scanner. Results: Of the 114 patients; 63(55.3%) were males and 51(44.7%) were females: Otorrhoea is the most common symptom, and was found in 113 patients constituting (99.1%) followed by Otolegia 69(60.5%) and headache affected 53(46.5%) of the cases. CSOM is more common in low socio-economic status .In ears affected with CSOM, the maximum CT number (Hounsfield) was found to be changed and was significantly affected with increasing patients’ age. Sclerotic changes and soft tissue density increased as the duration of CSOM increased in right and left middle ears significantly (F=5.802, Sig at 0.000), and (F=23.182, Sig at .015) respectively. Partial and complete erosion were detected in both right and left ossicle in the advanced phase of disease, where the ossicle still intact in the early stage , and the correlation is found to be significant with increasing of CSOM duration (F=16.959, Sig 0.000) and (F= 3.673, Sig =0.036)for right and left ossicles respectively. Changes including total and partial opacification, sclerotic changes, soft tissue density, mucosal thickening were the findings detected in both right and left mastoid in HRCT for temporal bone scanning. Conclusions: HRCT of temporal bone is useful in identifying various findings related to the location and extent of disease.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":"1 1","pages":"15-23"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78672161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.9790/0853-160603113117
C. OhamaemeMoses, N. EgwurugwuJude, C. EzealaGalina, R. OhamaemeChinyere, C. EbuenyiMartha
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