{"title":"Effects of the Posterior Margin of the Denture on the Functional Properties of Swallowing. 2. Decrease in Bolus Volume for One Swallowing and Prolongation of the Interval between Swallows in Forced, Repetitive Swallowing.","authors":"K. Hiraba, Nobuhiro Hasegawa, Yoshinori Desaki, Norie Nozaki, T. Ishida, Yoshinobu Tanaka","doi":"10.2330/JORALBIOSCI1965.43.392","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.43.392","url":null,"abstract":"義歯床の後縁の長さが嚥下運動に及ぼす影響を検索する目的で, Ah-lineより後方1.5, 1.0, 0.5, 0cmの4段階の口蓋床を装着させ, その影響を最大嚥下量, 1回嚥下量, 嚥下間隔に着目し, 含水嚥下と連続嚥下の異なる2種類の嚥下運動にて検討した。その結果, 口蓋床の影響は1.5cmの長さのときに最も強い影響が認められ, 後縁の短縮に伴いその影響は順次減少したが, その様相は含水嚥下と連続嚥下とで明らかに異なった。含水嚥下での嚥下間隔は口蓋床の影響をほとんど受けなかったのに対して, 連続嚥下では1.5cmの長さの口蓋床においてコントロール比127.8%もの有意な延長をきたした。また連続嚥下での1回嚥下量は0cmでもコントロールのレベルにまで回復しなかった。一方, 口蓋粘膜の浸潤麻酔は, 連続嚥下での1回嚥下量, 嚥下間隔に対してまったく影響を及ぼさなかったことより, 口蓋床の影響は口蓋粘膜からの感覚情報を遮断した結果ではなく, 舌ならびに軟口蓋などの関係部位の運動を物理的に妨げた結果であると結論した。","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"65 1","pages":"392-401"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84451247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Expression of Noggin Gene during Development of Maxillofacial Region in Mice","authors":"T. Inage, T. Nakada, D. Kamogawa, Yutaka Sakaguchi, Michitomo Sato, M. Ono, H. Kamogawa, T. Sekiwa, M. Terakado, F. Kuwata, Yoshinori Sato, S. Oida","doi":"10.2330/JORALBIOSCI1965.42.563","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.42.563","url":null,"abstract":"硬組織形成におけるnogginの機能を検索するために, 胎生11日から生後5日のマウスを用いてin situ hybridizationを行い, noggin mRNAの発現を観察した。体節形成期では, noggin mRNAのsignalは脳膜, 体節周囲の筋板に強く発現した。Meckel軟骨周囲の形成が開始されると, noggin mRNAはrestingおよびhypertrophic stageの軟骨細胞, 骨形成部位の骨芽細胞やその外側の結合組織細胞に著しく強く発現した。歯胚においては発現がきわめて弱いが, 歯小嚢外側の細胞には弱い発現がみられた。根間分岐部が形成期では, nogginは歯槽骨内側の骨芽細胞に強く発現した。根間分岐部の歯根膜および骨芽細胞には最も強い発現がみられた。体幹骨では骨膜のosteogenetic layerおよびfibrous layerにいたる細胞層に遺伝子が発現していた。","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"12 1","pages":"563-572"},"PeriodicalIF":0.0,"publicationDate":"2000-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83664507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-20DOI: 10.2330/JORALBIOSCI1965.42.527
T. Goto
{"title":"Neuropeptide, Substance P Modulates Bone Metabolism","authors":"T. Goto","doi":"10.2330/JORALBIOSCI1965.42.527","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.42.527","url":null,"abstract":"","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"33 1","pages":"527-535"},"PeriodicalIF":0.0,"publicationDate":"2000-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73072592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-20DOI: 10.2330/JORALBIOSCI1965.42.555
T. Hashimura, Michiko Sato, F. Nakazawa, E. Hoshino
: Eubacterium exiguum is a bacterial species of asaccharolytic anaerobic Gram-Positive rods (AAGPR) that are frequently isolated from human oral lesions. To clarify the phylogenetic relationship among oral AAGPR, we determined 16S rDNA gene sequence of E . exiguum (the type strain ATCC 700122 and 3 clinical strains) and compared with those of related oral AAGPR , including Cryptobacterium curtum, E. brachy, E. minutum, E. nodatum , E. saphenum, Mogibacterium timidum (former E. timidum) . The 16S rDNA sequence of E. exgiuum was high similarity between the type strain ATCC 700122 and 3 clinical strains (>99%) but clearly distinct from those of other oral AAGPR species and some typical oral Gram-Positive bacteria. Certain regions in the 16S rDNA were found to be common among 4 strains of E. exiguum but distinct from other bacterial species, thus the regions were species-specific. In fact, 5 pairs of primers (exg 129F and exg 576R, exg 129F and exg 605R , exg 129F and exg 1263R, exg 557F and exg 1263R, exg 586F and exg 1263R),
{"title":"Phylogenetic Analysis of 16S rDNA of Eubacterium exiguum and the Species-specific Regions for Primer Designation","authors":"T. Hashimura, Michiko Sato, F. Nakazawa, E. Hoshino","doi":"10.2330/JORALBIOSCI1965.42.555","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.42.555","url":null,"abstract":": Eubacterium exiguum is a bacterial species of asaccharolytic anaerobic Gram-Positive rods (AAGPR) that are frequently isolated from human oral lesions. To clarify the phylogenetic relationship among oral AAGPR, we determined 16S rDNA gene sequence of E . exiguum (the type strain ATCC 700122 and 3 clinical strains) and compared with those of related oral AAGPR , including Cryptobacterium curtum, E. brachy, E. minutum, E. nodatum , E. saphenum, Mogibacterium timidum (former E. timidum) . The 16S rDNA sequence of E. exgiuum was high similarity between the type strain ATCC 700122 and 3 clinical strains (>99%) but clearly distinct from those of other oral AAGPR species and some typical oral Gram-Positive bacteria. Certain regions in the 16S rDNA were found to be common among 4 strains of E. exiguum but distinct from other bacterial species, thus the regions were species-specific. In fact, 5 pairs of primers (exg 129F and exg 576R, exg 129F and exg 605R , exg 129F and exg 1263R, exg 557F and exg 1263R, exg 586F and exg 1263R),","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"18 1","pages":"555-562"},"PeriodicalIF":0.0,"publicationDate":"2000-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72684163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-20DOI: 10.2330/JORALBIOSCI1965.42.590
Y. Saeki, Mitsuru Takahashi, Shingo Kamikawa, Takumi Tokumoto, Y. Miake, S. Yamada, K. Okuda, T. Yanagisawa
: The objective of the present study was to investigate the beneficial effects of xylitol chewing gum containing Gloiopeltis furcata extract and calcium hydrogenphosphate on remineralization of initial caries like enamel lesions. Initial caries-like enamel lesions were artificially prepared by demineralizing human enamel blocks with a O.01M acetate buffer (pH 4.0) at 50℃ . We investigated sucrose gum (control), xylitol gum, and xylitol gum containing G. furcata extract and calcium hydrogenphosphate . In the in vitro intvestiga- tion,the enamel blocks having initial caries-like enamel lesions were immersed in a remineralizing solution containing the extract of each chewing gum at 37℃ for 2 weeks , and then evaluated for degrees of remineralization by contact microradiography . The remineralizing potential of each chewing gum in vivo was also evaluated by an oral device fixed with artificially demineralized human enamel block. Each subject was fixed on this device on the lingual surface of the mandibular molar for one week , and was given chewing gum samples 7 times a day. This in vivo study was carried out by the double-blind method .
{"title":"Remineralization Effect of Xylitol Chewing Gum Containing Gloiopeltis furcata Extract and Calcium Hydrogenphosphate on Initial Caries-like Enamel Lesions","authors":"Y. Saeki, Mitsuru Takahashi, Shingo Kamikawa, Takumi Tokumoto, Y. Miake, S. Yamada, K. Okuda, T. Yanagisawa","doi":"10.2330/JORALBIOSCI1965.42.590","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.42.590","url":null,"abstract":": The objective of the present study was to investigate the beneficial effects of xylitol chewing gum containing Gloiopeltis furcata extract and calcium hydrogenphosphate on remineralization of initial caries like enamel lesions. Initial caries-like enamel lesions were artificially prepared by demineralizing human enamel blocks with a O.01M acetate buffer (pH 4.0) at 50℃ . We investigated sucrose gum (control), xylitol gum, and xylitol gum containing G. furcata extract and calcium hydrogenphosphate . In the in vitro intvestiga- tion,the enamel blocks having initial caries-like enamel lesions were immersed in a remineralizing solution containing the extract of each chewing gum at 37℃ for 2 weeks , and then evaluated for degrees of remineralization by contact microradiography . The remineralizing potential of each chewing gum in vivo was also evaluated by an oral device fixed with artificially demineralized human enamel block. Each subject was fixed on this device on the lingual surface of the mandibular molar for one week , and was given chewing gum samples 7 times a day. This in vivo study was carried out by the double-blind method .","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"2 1","pages":"590-600"},"PeriodicalIF":0.0,"publicationDate":"2000-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79699011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-20DOI: 10.2330/JORALBIOSCI1965.42.573
M. Matsuo, C. Su, M. Saito, Y. Kishi, Kazuto Takahashi
This study evaluated a case which was unsuccessful after guided bone regeneration (GBR) operation with non-resorbable barrier membranes in the extraction socket of a beagle dog. To clarify the relationship between bone and vascular regeneration, a vascular resin cast model was observed under a scanning electron microscope (SEM).At 30 days post-operation, vessels from the periosteum were seen migrating to the socket through the gap between the membrane and the bone wall. The regenerated bone height was no higher than that of the pre-existing alveolar crest.At 60 days post-operation, the height of the regenerated bone was in accordance with that of the Pre-existing bone. A vascular network of granulation tissue was seen between the membrane and the upper margin of the alveolar bone. This vascular network consisted of a densely arranged vascular loop. The tracing of the circulatory pathway revealed that this network was composed of arteries from the alveolar bone marrow and veins of large diameter, which drained to the oral mucosa. The surface of a granulation tissue vessel showed a rough configuration. Resin was found to be leaking from the vascular loops.The study of this unsuccessful case clearly showed that the membrane was neither in close contact to the surrounding bone wall nor sufficiently supported by it. This resulted in an ingrowth of vessels from the periosteum to the socket. Consequently, there was no increase in bone height growth and new bone apposition did not occur. To succeed with GBR, it is essential that vascularization of the periosteum occur and that the membrane gradually cover and seal the extraction socket.
{"title":"Vascularization of an Unsuccessful Case Following Guided Bone Regeneration","authors":"M. Matsuo, C. Su, M. Saito, Y. Kishi, Kazuto Takahashi","doi":"10.2330/JORALBIOSCI1965.42.573","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.42.573","url":null,"abstract":"This study evaluated a case which was unsuccessful after guided bone regeneration (GBR) operation with non-resorbable barrier membranes in the extraction socket of a beagle dog. To clarify the relationship between bone and vascular regeneration, a vascular resin cast model was observed under a scanning electron microscope (SEM).At 30 days post-operation, vessels from the periosteum were seen migrating to the socket through the gap between the membrane and the bone wall. The regenerated bone height was no higher than that of the pre-existing alveolar crest.At 60 days post-operation, the height of the regenerated bone was in accordance with that of the Pre-existing bone. A vascular network of granulation tissue was seen between the membrane and the upper margin of the alveolar bone. This vascular network consisted of a densely arranged vascular loop. The tracing of the circulatory pathway revealed that this network was composed of arteries from the alveolar bone marrow and veins of large diameter, which drained to the oral mucosa. The surface of a granulation tissue vessel showed a rough configuration. Resin was found to be leaking from the vascular loops.The study of this unsuccessful case clearly showed that the membrane was neither in close contact to the surrounding bone wall nor sufficiently supported by it. This resulted in an ingrowth of vessels from the periosteum to the socket. Consequently, there was no increase in bone height growth and new bone apposition did not occur. To succeed with GBR, it is essential that vascularization of the periosteum occur and that the membrane gradually cover and seal the extraction socket.","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"2017 1","pages":"573-579"},"PeriodicalIF":0.0,"publicationDate":"2000-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86760384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2000-12-20DOI: 10.2330/JORALBIOSCI1965.42.580
Y. Miake, T. Yanagisawa
: This is a morphological investigation of the influence of xylitol on remineralization in experimen tally demineralized dental enamel . Materials were human third molars , the dental surfaces of which had been demineralized. The samples were immersed at 37℃ for 2, 4, and 8 weeks in either a remineralizing solution (Ca: 1mM, P: 2mM, F: 0.2PPm) containing 10% xylitol or a remineralizing solution without xylitol . Specimens were then prepared as ground sections (100μm) and contact-microradiograms were obtained . Degrees of mineralization were measured by Multipurpose Image Processor . Results showed that, in the no-xylitol group, remineralization had occurred in the surface layer but not in the intermediate and deep layers.
{"title":"Effects of Xylitol on Remineralization of Artificial Demineralized Enamel","authors":"Y. Miake, T. Yanagisawa","doi":"10.2330/JORALBIOSCI1965.42.580","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.42.580","url":null,"abstract":": This is a morphological investigation of the influence of xylitol on remineralization in experimen tally demineralized dental enamel . Materials were human third molars , the dental surfaces of which had been demineralized. The samples were immersed at 37℃ for 2, 4, and 8 weeks in either a remineralizing solution (Ca: 1mM, P: 2mM, F: 0.2PPm) containing 10% xylitol or a remineralizing solution without xylitol . Specimens were then prepared as ground sections (100μm) and contact-microradiograms were obtained . Degrees of mineralization were measured by Multipurpose Image Processor . Results showed that, in the no-xylitol group, remineralization had occurred in the surface layer but not in the intermediate and deep layers.","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"40 1","pages":"580-589"},"PeriodicalIF":0.0,"publicationDate":"2000-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81670238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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