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Diversity and Distribution of Bacterial and Parasitic Tick-Borne Pathogens in Armenia, Transcaucasia. 外高加索亚美尼亚蜱传细菌和寄生虫病原体的多样性和分布。
IF 1.4 4区 医学 Q3 Medicine Pub Date : 2024-11-01 DOI: 10.18502/ijph.v53i11.16960
Sargis A Aghayan, Gohar Grigoryan, Hasmik Gevorgyan, Tehmine Harutyunyan, Martin Rukhkyan, Vahagn Muradyan, Gregory Karadjian, Maud Marsot, Sara Moutailler, Thomas Pollet

Background: Variations in the distribution and prevalence of pathogens in ticks can have significant consequences for human health. Information on these variables in Transcaucasia is scarce, so the aim of our study was to conduct a large-scale study to detect selected tick-borne infectious agents in Armenia.

Methods: Overall, 209 adult ticks were collected from different hosts including 4 samples from human clothes. We tested ticks using high-throughput microfluidic single-cell real-time PCR to detect 42 genospecies of pathogens. We used GIS to determine biotic and abiotic factors governing the prevalence of pathogens and applied statistical analyses to test the association between prevalence of pathogens depending on hosts, locality and environment.

Results: From 209 samples, 134 were positive to targeted pathogens. Anaplasma phagocytophilum Foggie, 1949 was the most prevalent case (44%). The highest overall prevalence was observed in ticks from sheep (74%), followed by cows (67%) and calves (60%). The highest multiple infection rates were also detected in sheep (40%) and calves (40%) followed by cows (28%). One statistically significant association was found among co-infections (P<0.05). The prevalence of pathogens varied according to locality. The abundance of Anaplasma spp. is significantly correlated with "slope" and "vegetation" factors. Similar patterns were detected for other pathogens.

Conclusion: This was the first large-scale survey of multiple tick-borne pathogens in Armenia and Transcaucasia. The results of this study shed light on spatial variations in pathogen infection rate among adult ticks found on hosts and underline a number of environmental determinants of pathogen distribution among ticks.

背景:蜱中病原体分布和流行的变化可能对人类健康产生重大影响。外高加索地区关于这些变量的信息很少,因此我们研究的目的是进行一项大规模研究,以检测亚美尼亚选定的蜱传感染原。方法:从不同寄主采集成蜱209只,其中人衣采集成蜱4只。采用高通量微流控单细胞实时荧光定量PCR对蜱进行检测,检测出42种病原菌。我们使用GIS来确定控制病原体流行的生物和非生物因素,并应用统计分析来测试病原体流行与宿主、地点和环境之间的关系。结果:209份标本中靶菌阳性134份。1949年的嗜吞噬细胞无原体是最常见的病例(44%)。总体流行率最高的是羊蜱(74%),其次是牛蜱(67%)和小牛蜱(60%)。多重感染率最高的是绵羊(40%)和小牛(40%),其次是奶牛(28%)。在共感染中发现有统计学意义的关联(PAnaplasma spp.与“坡度”和“植被”因素显著相关)。在其他病原体中也发现了类似的模式。结论:这是亚美尼亚和外高加索地区首次大规模调查蜱传多种病原体。本研究结果揭示了寄主成年蜱中病原体感染率的空间变化,并强调了蜱中病原体分布的一些环境决定因素。
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引用次数: 0
Insights into Health Program Implementation and Evaluation in Iran: A Brief Review of National Healthcare Programs in Iran. 对伊朗卫生计划实施和评估的见解:伊朗国家卫生保健计划的简要回顾。
IF 1.4 4区 医学 Q3 Medicine Pub Date : 2024-11-01 DOI: 10.18502/ijph.v53i11.16961
Reyhaneh Ehsani, Maedeh Sharafoddin, Alireza Olyaeemanesh, Alireza Delavari, Abbas Vosoogh-Moghaddam, Yousef Alimohamadi, Sheida Ghorbani

Background: Healthcare program monitoring can play a key role in evaluating their implementation and identifying their strengths and weaknesses.

Methods: This study was performed with the exploratory sequential mixed methods design in 2023 at Tehran, Iran. The information was categorized into indicators, refining, analysis, interpretation, reporting, and proposed challenges and recommendations.

Results: Medical Sciences Department of Public Health (TUMSDoPH) evaluation of its public health programs revealed a comprehensive approach covering a wide spectrum from disease management to health promotion, emphasizing electronic health records, targeted disease interventions, and strategies for non-communicable diseases, alongside efforts to enhance community health.

Conclusion: There is a need for initiating "the monitoring committee" under the supervision of the deputy chancellor for public health to monitor key performance indicators and policies to discover the problems of each part of the health system and provide recommendations.

背景:医疗保健计划监控可以在评估其实施和确定其优缺点方面发挥关键作用。方法:本研究采用探索性顺序混合方法设计,于2023年在伊朗德黑兰进行。这些信息被分为指标、提炼、分析、解释、报告以及提出的挑战和建议。结果:公共卫生医学科学系(TUMSDoPH)对其公共卫生计划的评估揭示了一种全面的方法,涵盖了从疾病管理到健康促进的广泛范围,强调电子健康记录、有针对性的疾病干预和非传染性疾病战略,以及加强社区健康的努力。结论:有必要在公共卫生部副部长的监督下成立“监测委员会”,对关键绩效指标和政策进行监测,发现卫生系统各部分存在的问题并提出建议。
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引用次数: 0
Oncoming Revolution in the Next Generation of Cohort Studies. 下一代队列研究即将到来的革命。
IF 1.4 4区 医学 Q3 Medicine Pub Date : 2024-11-01 DOI: 10.18502/ijph.v53i11.16963
Hossein Moameri, Mojtaba Norouzi, Ali Akbar Haghdoost, Mostafa Hosseini Golkar

The world is changing rapidly, mainly due to the impact of megatrends that have an impact on the entire human life, particularly in medical sciences. Medical research methodologies such as cohort studies provide very critical information, but it is not clear what would be its destination in the future. In this short article, we have tried to offer a somewhat different perspective on the future of cohort studies by analyzing the texts and their conclusions from the author's viewpoint. According to our assessment, cohorts will play a key role in medical research, but their methodology will significantly change in terms of designing, implementing, analysing, and applying the findings. The new generation of cohort study extracts most of their information from electronic health records, and it is not just restricted to a particular geographic area. With the changes in the levels of occupational exposure, risk factors, and the introduction of Omics, likely, occupational and birth cohorts as well as human diseases will likely undergo fundamental changes in the future. Big data will provide researchers with new opportunities, but information extraction and analysis require a team of specialists from several scientific fields. Furthermore, participants are likely to play a more active role in setting priorities and implementing research findings.

世界正在迅速变化,这主要是由于对整个人类生活,特别是医学科学产生影响的大趋势的影响。诸如队列研究之类的医学研究方法提供了非常关键的信息,但尚不清楚其未来的目标是什么。在这篇短文中,我们试图通过从作者的角度分析文本及其结论,为队列研究的未来提供一个不同的视角。根据我们的评估,队列将在医学研究中发挥关键作用,但其方法将在设计、实施、分析和应用研究结果方面发生重大变化。新一代的队列研究从电子健康记录中提取了他们的大部分信息,而且它不仅仅局限于特定的地理区域。随着职业暴露水平、风险因素的变化以及组学的引入,职业和出生队列以及人类疾病在未来可能会发生根本性的变化。大数据将为研究人员提供新的机会,但信息提取和分析需要来自多个科学领域的专家团队。此外,参与者可能在确定优先事项和实施研究成果方面发挥更积极的作用。
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引用次数: 0
Understanding the Relationship between Sleep Quality and Physical Activity: Implications for Healthy Aging. 了解睡眠质量和身体活动之间的关系:对健康老龄化的影响。
IF 1.4 4区 医学 Q3 Medicine Pub Date : 2024-11-01 DOI: 10.18502/ijph.v53i11.16952
Hyun Byun, Suyoung Hwang, Eunsurk Yi, Ladan Rokni

Background: Understanding the general health and well-being of the aged population requires an understanding of several factors, among which the interplay between physical activity and sleep quality are the most efficient determinants. There is still much to learn about the precise ways that different components of sleep quality affect different kinds of physical activity in older persons, accordingly, the study aims to provide a comprehensive understanding of the interaction between these variables.

Methods: An online questionnaire-based investigation was conducted between August and September 2023. This cross-sectional study analyzed data from 1,437 participants aged 50 to 89 years. The questionnaire evaluated levels of physical activity, sleep satisfaction, and demographic data. We used cluster analysis, regression analysis, and factor analysis to investigate the connections between these variables.

Results: Factor analysis revealed a single factor that accounted for 51.95% of the variance in all variables linked to sleep, and this factor represented overall quality of sleep. Regression analysis revealed that gender significantly predicted sleep quality, with females reporting lower sleep satisfaction. While strenuous exercise did not significantly affect sleep quality, moderate exercise was a positive predictor of sleep quality that neared statistical significance. Furthermore, cluster analysis revealed that those who engaged in more physical activity had higher-quality sleep.

Conclusion: These results highlight the significance of encouraging physical activity to improve older adults' sleep quality. Specific programs that promote moderate exercise may enhance this population's general health and sleep quality. Future research should focus on longitudinal studies to create causality and modify intervention strategies aimed at promoting healthy aging.

背景:了解老年人口的总体健康和福祉需要了解几个因素,其中身体活动和睡眠质量之间的相互作用是最有效的决定因素。关于睡眠质量的不同组成部分影响老年人不同类型身体活动的确切方式,还有很多需要了解的,因此,这项研究旨在全面了解这些变量之间的相互作用。方法:于2023年8 - 9月进行在线问卷调查。这项横断面研究分析了1437名年龄在50至89岁之间的参与者的数据。调查问卷评估了身体活动水平、睡眠满意度和人口统计数据。我们使用聚类分析、回归分析和因子分析来研究这些变量之间的联系。结果:因子分析显示,在与睡眠相关的所有变量中,单一因素占51.95%的方差,该因素代表了整体睡眠质量。回归分析显示,性别对睡眠质量有显著影响,女性的睡眠满意度较低。虽然剧烈运动对睡眠质量没有显著影响,但适度运动是睡眠质量的积极预测因子,接近统计学意义。此外,聚类分析显示,那些参加更多体育活动的人睡眠质量更高。结论:这些结果强调了鼓励体育锻炼对改善老年人睡眠质量的重要性。促进适度运动的具体计划可能会改善这一人群的总体健康状况和睡眠质量。未来的研究应侧重于纵向研究,以建立因果关系,并修改旨在促进健康老龄化的干预策略。
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引用次数: 0
Factors Influencing Children's Hospital Nurses' Safety Accident Management Activities for Hospitalized Children. 影响儿童医院护士住院儿童安全事故管理活动的因素。
IF 1.4 4区 医学 Q3 Medicine Pub Date : 2024-11-01 DOI: 10.18502/ijph.v53i11.16954
Se Hwa Park, Jin Hee Lee

Background: We aimed to identify the factors influencing safety accident management activities for hospitalized children in children's hospitals.

Methods: In August 2022, data were collected from 170 nurses across seven children's hospitals in Gwangju Metropolitan City, Korea. The collected data were analyzed using independent t-tests, analysis of variance, Pearson's correlation analysis, and multiple regression analysis.

Results: Safety accident management activities for hospitalized children differ significantly based on nurses' experience in children's hospitals (P=0.048) . Safety accident management activities were positively correlated with patient safety culture (r=0.47, P<0.001) , critical thinking (r=0.35, P<0.001) , and nursing work environment (r=0.51, P<0.001) . Furthermore, the most influential determinant of safety accident management activities for hospitalized children was the nursing work environment (β=0.42, P<0.001) , followed by nurses' experience in children's hospitals (β=0.20, P=0.004) , and patient safety culture (β=0.17, P=0.041) . These variables had an explanatory power of 34.0 % (adjusted R2=0.34, P<0.001) .

Conclusion: A positive nursing work environment and strong patient safety culture are essential for increasing safety accident management activities among children's hospital nurses. Additionally, children's hospitals should provide support to the nursing staff and implement policies that encourage long-term retention of experienced nurses.

背景:本研究旨在了解儿童医院住院儿童安全事故管理活动的影响因素。方法:于2022年8月对韩国光州市7家儿童医院的170名护士进行数据采集。对收集的资料进行独立t检验、方差分析、Pearson相关分析和多元回归分析。结果:住院儿童安全事故管理活动与儿童医院护士经验差异显著(P=0.048)。安全事故管理活动与患者安全培养(r=0.47, PPPPP=0.004)、患者安全培养(β=0.17, P=0.041)呈正相关。这些变量的解释能力为34.0%(调整后R2=0.34)。结论:积极的护理工作环境和牢固的患者安全文化是提高儿童医院护士安全事故管理活动的必要条件。此外,儿童医院应为护理人员提供支持,并实施鼓励长期保留有经验的护士的政策。
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引用次数: 0
Features of Changes in Heart Rate Variability among Medical Students during the Education Process. 医学生在教育过程中心率变异性的变化特点
IF 1.4 4区 医学 Q3 Medicine Pub Date : 2024-11-01 DOI: 10.18502/ijph.v53i11.16959
Ainura Manasovna Satarkulova, Asel Abdumomunovna Usenova, Shirin Syrgakovna Bakirova, Shadiya Yusupdjanovna Aisaeva, Kanykei Sadyrbekovna Keneshova, Meerim Turdubekovna Turdubekova

Background: We investigated the changes of Heart Rate Variability (HRV) parameters, which reflect the state of the regulatory mechanisms of cardiovascular system, among medical students during routine academic period and examination session.

Methods: The study was conducted in Jan-Feb 2024, at the IHSM in Bishkek, Kyrgyz Republic, among the healthy 70 students (mean age 19.71 ± 1.54 years) from India and Pakistan. For each student, two ECG recordings were performed: one 3 weeks before the exam and one 10-15 minutes after exam.

Results: The results of study demonstrated that after the exam, students presented significantly higher HR, AMo, SI, VLF, LF and lower SDNN, TP, HF compared before the exam (P<0.05). Distribution of students showed that on a routine academic period 53% of students belonged to sympathotonic, 14% to vagotonic and 33% to normotonic. During the examination period the number of sympathotonic increased to 74%, but the number of vagotonic and normotonic decreased to 4% and 22% respectively.

Conclusion: Each type revealed an individual reaction to exam stress: in the group of vagotonic there was a slight activation of the SNS; in sympathotonic students there was a tension of regulatory mechanisms, leading to depletion of adaptive mechanisms; in the group of normotonic there was a shift in the vegetative balance towards the sympathetic link of ANS.

背景:研究医学生在常规学习期间和考试期间反映心血管系统调节机制状态的心率变异性(HRV)参数变化。方法:研究于2024年1 - 2月在吉尔吉斯共和国比什凯克IHSM进行,研究对象为来自印度和巴基斯坦的70名健康学生(平均年龄19.71±1.54岁)。对每个学生进行两次心电图记录:一次是在考试前3周,一次是在考试后10-15分钟。结果:研究结果表明,考试后,学生的HR、AMo、SI、VLF、LF明显高于考试前,SDNN、TP、HF明显低于考试前(p)。结论:每种类型对考试压力的反应都有个体差异:迷走紧张性组有轻微的SNS激活;在交感神经性学生中,调节机制存在张力,导致适应机制的耗竭;在常压组中,植物平衡向ANS的交感神经链转移。
{"title":"Features of Changes in Heart Rate Variability among Medical Students during the Education Process.","authors":"Ainura Manasovna Satarkulova, Asel Abdumomunovna Usenova, Shirin Syrgakovna Bakirova, Shadiya Yusupdjanovna Aisaeva, Kanykei Sadyrbekovna Keneshova, Meerim Turdubekovna Turdubekova","doi":"10.18502/ijph.v53i11.16959","DOIUrl":"https://doi.org/10.18502/ijph.v53i11.16959","url":null,"abstract":"<p><strong>Background: </strong>We investigated the changes of Heart Rate Variability (HRV) parameters, which reflect the state of the regulatory mechanisms of cardiovascular system, among medical students during routine academic period and examination session.</p><p><strong>Methods: </strong>The study was conducted in Jan-Feb 2024, at the IHSM in Bishkek, Kyrgyz Republic, among the healthy 70 students (mean age 19.71 ± 1.54 years) from India and Pakistan. For each student, two ECG recordings were performed: one 3 weeks before the exam and one 10-15 minutes after exam.</p><p><strong>Results: </strong>The results of study demonstrated that after the exam, students presented significantly higher HR, AMo, SI, VLF, LF and lower SDNN, TP, HF compared before the exam (<i>P</i><0.05). Distribution of students showed that on a routine academic period 53% of students belonged to sympathotonic, 14% to vagotonic and 33% to normotonic. During the examination period the number of sympathotonic increased to 74%, but the number of vagotonic and normotonic decreased to 4% and 22% respectively.</p><p><strong>Conclusion: </strong>Each type revealed an individual reaction to exam stress: in the group of vagotonic there was a slight activation of the SNS; in sympathotonic students there was a tension of regulatory mechanisms, leading to depletion of adaptive mechanisms; in the group of normotonic there was a shift in the vegetative balance towards the sympathetic link of ANS.</p>","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"53 11","pages":"2551-2562"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of Hepatitis C Virus Infection in Tuberculosis Patients: A Systematic Review and Meta-Analysis. 结核病患者丙型肝炎病毒感染的风险:一项系统综述和荟萃分析
IF 1.4 4区 医学 Q3 Medicine Pub Date : 2024-11-01 DOI: 10.18502/ijph.v53i11.16947
Neda Amoori, Bahman Cheraghian, Payam Amini, Seyed Mohammad Alavi

Background: Tuberculosis (TB) and infection of Hepatitis C virus (HCV) have appeared as major public health problems. The present systematic review and meta-analysis aimed at determining the relationship between TB and the risk of HCV infection.

Methods: Google Scholar, Embase, Medline, Pubmed, web of sciences (ISI), and Scopus were searched until March 2022. The pooled ORs of HCV in patients with TB were calculated utilizing the random-effect model with a 95% confidence interval (CI). I2 test was utilized for evaluating the heterogeneity. To check publication bias Egger and Beggs' tests were used.

Results: From among 1500 articles from 2006 to 2020, 13 studies were examined and analyzed based on the inclusion/exclusion criteria. The overall risk of HCV infection in patients with TB was (OR: 1.34, 95% CI: 1.10-1.63, P=0.001). According to the type of the countries subgroup analysis, the risk of HCV infection in patients with TB in developing countries was (OR: 1.95, 95% CI: 1.00-3.80), which was higher than the risk in developed countries (OR: 1.47, 95% CI: 1.42-1.52). In addition, the risk of hepatitis C infection in men compared to women (OR: 1.84, 95% CI: 1.75-1.94, P=0.001) and in age groups over 65 yr compared to other age groups (OR: 1.46, 95% CI: 0.98-2.16) was significantly higher.

Conclusion: The results of this study emphasized the importance of screening HCV in patients with TB. Being aware of the presence or absence of HCV in these patients can contribute to their effective treatment.

背景:结核病(TB)和丙型肝炎病毒(HCV)感染已成为主要的公共卫生问题。本系统综述和荟萃分析旨在确定结核病与丙型肝炎病毒感染风险之间的关系。方法:截至2022年3月,检索谷歌Scholar、Embase、Medline、Pubmed、web of sciences (ISI)和Scopus。利用随机效应模型计算结核患者HCV的合并or值,置信区间为95%。采用I2检验评价异质性。为了检查发表偏倚,我们使用了Egger和Beggs的检验。结果:在2006 - 2020年的1500篇文献中,根据纳入/排除标准对13项研究进行了检查和分析。结核病患者感染丙型肝炎病毒的总风险为(OR: 1.34, 95% CI: 1.10-1.63, P=0.001)。根据国家亚组分析的类型,发展中国家结核病患者HCV感染的风险为(OR: 1.95, 95% CI: 1.00-3.80),高于发达国家的风险(OR: 1.47, 95% CI: 1.42-1.52)。此外,男性丙型肝炎感染的风险与女性相比(OR: 1.84, 95% CI: 1.75-1.94, P=0.001), 65岁以上年龄组与其他年龄组相比(OR: 1.46, 95% CI: 0.98-2.16)显著更高。结论:本研究结果强调了在结核病患者中筛查丙型肝炎病毒的重要性。了解这些患者是否存在丙型肝炎病毒有助于对其进行有效治疗。
{"title":"Risk of Hepatitis C Virus Infection in Tuberculosis Patients: A Systematic Review and Meta-Analysis.","authors":"Neda Amoori, Bahman Cheraghian, Payam Amini, Seyed Mohammad Alavi","doi":"10.18502/ijph.v53i11.16947","DOIUrl":"https://doi.org/10.18502/ijph.v53i11.16947","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) and infection of Hepatitis C virus (HCV) have appeared as major public health problems. The present systematic review and meta-analysis aimed at determining the relationship between TB and the risk of HCV infection.</p><p><strong>Methods: </strong>Google Scholar, Embase, Medline, Pubmed, web of sciences (ISI), and Scopus were searched until March 2022. The pooled ORs of HCV in patients with TB were calculated utilizing the random-effect model with a 95% confidence interval (CI). <b>I<sup>2</sup></b> test was utilized for evaluating the heterogeneity. To check publication bias Egger and Beggs' tests were used.</p><p><strong>Results: </strong>From among 1500 articles from 2006 to 2020, 13 studies were examined and analyzed based on the inclusion/exclusion criteria. The overall risk of HCV infection in patients with TB was (OR: 1.34, 95% CI: 1.10-1.63, <i>P</i>=0.001). According to the type of the countries subgroup analysis, the risk of HCV infection in patients with TB in developing countries was (OR: 1.95, 95% CI: 1.00-3.80), which was higher than the risk in developed countries (OR: 1.47, 95% CI: 1.42-1.52). In addition, the risk of hepatitis C infection in men compared to women (OR: 1.84, 95% CI: 1.75-1.94, <i>P</i>=0.001) and in age groups over 65 yr compared to other age groups (OR: 1.46, 95% CI: 0.98-2.16) was significantly higher.</p><p><strong>Conclusion: </strong>The results of this study emphasized the importance of screening HCV in patients with TB. Being aware of the presence or absence of HCV in these patients can contribute to their effective treatment.</p>","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"53 11","pages":"2451-2461"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends and Projections of Mortality Attributed to Occupational Neoplasms and Occupational Tracheal, Bronchus, and Lung Cancer in the World, G7 Countries and Turkey. 世界、G7国家和土耳其职业肿瘤和职业性气管、支气管和肺癌死亡率的趋势和预测。
IF 1.4 4区 医学 Q3 Medicine Pub Date : 2024-11-01 DOI: 10.18502/ijph.v53i11.16950
Elif Nur Yıldırım-Ozturk, Mustafa Ozturk

Background: The most important and remarkable aspect of occupational neoplasms is that they are preventable. We aimed to examine the trends and projections of mortality rates attributed to occupational neoplasms (MAON) and occupational tracheal, bronchus, and lung cancer (MAOLCa) in the world, G7 countries, and Turkey from 1990 to 2040.

Methods: The study was ecological one. Data for the study were obtained from the Global Burden of Disease (GBD) Foresight Visualization. For the study, time points were set every five years. For each time point, the age-standardized MAON, MAOLCa, and their 95% confidence intervals (CIs) were recorded. Rates were analyzed by joinpoint regression analysis.

Results: Globally, MAON was projected to decrease from 3.81% in 1990 to 2.83% in 2040. According to the joinpoint regression analysis, the joint year for the world was 2020. In Germany, the US, the UK, Italy, Canada and Turkey, the trend for MAON showed a decrease, similar to the global trend. However, MAON was stable in France and increased in Japan. Globally, MAOLCa was expected to decline gradually from 19.44% to 16.82% from 1990 to 2040. In the US, France and Turkey, the trend for MAOLca decreased, similar to the global trend. However, it was stable in the UK, Italy, and Canada and increased in Germany and Japan.

Conclusion: MAON tended to decrease worldwide and in the six countries, except France and Japan. MAOLCa tends to decrease worldwide, in the US, France, and Turkey, increase in Germany and Japan, and remain stable in the UK, Italy, and Canada.

背景:职业性肿瘤最重要和最显著的特点是可预防。我们的目的是研究1990年至2040年世界、G7国家和土耳其职业性肿瘤(MAON)和职业性气管、支气管和肺癌(MAOLCa)死亡率的趋势和预测。方法:生态学研究。该研究的数据来自全球疾病负担(GBD)预见可视化。在这项研究中,时间点每五年设定一次。记录每个时间点的年龄标准化MAON、MAOLCa及其95%置信区间(ci)。采用关节点回归分析对发病率进行分析。结果:全球MAON预计将从1990年的3.81%下降到2040年的2.83%。根据联结点回归分析,全球的联结点年是2020年。在德国、美国、英国、意大利、加拿大和土耳其,MAON的趋势与全球趋势相似,呈下降趋势。然而,MAON在法国保持稳定,在日本有所上升。在全球范围内,预计MAOLCa从1990年的19.44%逐渐下降到2040年的16.82%。在美国、法国和土耳其,MAOLca的趋势与全球趋势相似,呈下降趋势。然而,在英国、意大利和加拿大,这一数字保持稳定,在德国和日本则有所上升。结论:MAON在世界范围内呈下降趋势,除法国和日本外,其余6个国家均呈下降趋势。MAOLCa在世界范围内呈下降趋势,在美国、法国和土耳其,MAOLCa在德国和日本呈上升趋势,在英国、意大利和加拿大保持稳定。
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引用次数: 0
Effectiveness of Acupuncture for Diabetic Nephropathy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. 针灸治疗糖尿病肾病的有效性:随机对照试验的系统评价和荟萃分析。
IF 1.4 4区 医学 Q3 Medicine Pub Date : 2024-11-01 DOI: 10.18502/ijph.v53i11.16942
Cui Wu, Yuandong Li, Chunli Piao, Jiuru Wu

Background: This systematic review and meta-analysis aimed to explore the effectiveness of acupuncture for patients with diabetic nephropathy (DN).

Methods: Nine online databases were searched: China National Knowledge Infrastructure, China Science and Technology Journal Database, Wanfang Data Knowledge Service Platform, Chinese BioMedical Literature Database, China Clinical Trial Centre, Embase, PubMed, the Cochrane Library, and Web of Science. The search period was from the establishment of the database to 1 September 2023. The quality of the literature was evaluated using the Cochrane Risk of Bias Assessment Tool, and the data were analyzed using STATA/MP17 and Review Manager 5.3 software.

Results: A total of 221 articles were identified, and 13 studies were included. The total sample size was 899, including 452 and 447 cases in the experimental and control groups, respectively. The meta-analysis showed that acupuncture combined with modern medical treatment was effective in improving urinary albumin excretion rate, 24 h urinary microalbumin, serum creatinine, blood urea nitrogen, fasting plasma glucose, 2 h post-prandial plasma glucose, total cholesterol, high-density lipoprotein cholesterol, hypersensitive C-reactive protein, and interleukin-6 in patients with DN. Adverse events were reported in only one trial; therefore, this review cannot yet conclude on the safety of acupuncture intervention in DN.

Conclusion: The clinical efficacy of acupuncture combined with modern medicine in DN is superior to that of modern medicine alone. To better evaluate the efficacy and safety of acupuncture intervention for DN, more rigorously designed large-sample, multicentre, randomized controlled trials are needed to provide evidence support in the future.

背景:本系统综述和荟萃分析旨在探讨针灸治疗糖尿病肾病(DN)的有效性。方法:检索中国国家知识基础设施、中国科技期刊库、万方数据知识服务平台、中国生物医学文献库、中国临床试验中心、Embase、PubMed、Cochrane图书馆、Web of Science等9个在线数据库。检索期为数据库建立至2023年9月1日。采用Cochrane偏倚风险评估工具对文献质量进行评价,采用STATA/MP17和Review Manager 5.3软件对数据进行分析。结果:共纳入221篇文献,纳入13项研究。总样本量为899例,其中实验组452例,对照组447例。荟萃分析显示,针刺结合现代医学治疗可有效改善DN患者尿白蛋白排泄率、24 h尿微量白蛋白、血清肌酐、血尿素氮、空腹血糖、餐后2 h血糖、总胆固醇、高密度脂蛋白胆固醇、超敏c反应蛋白、白细胞介素-6。只有一项试验报告了不良事件;因此,本综述尚未得出针刺干预DN的安全性结论。结论:针刺结合现代医学治疗DN的临床疗效优于单用现代医学。为了更好地评价针刺干预DN的疗效和安全性,未来需要更严格设计的大样本、多中心、随机对照试验来提供证据支持。
{"title":"Effectiveness of Acupuncture for Diabetic Nephropathy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Cui Wu, Yuandong Li, Chunli Piao, Jiuru Wu","doi":"10.18502/ijph.v53i11.16942","DOIUrl":"https://doi.org/10.18502/ijph.v53i11.16942","url":null,"abstract":"<p><strong>Background: </strong>This systematic review and meta-analysis aimed to explore the effectiveness of acupuncture for patients with diabetic nephropathy (DN).</p><p><strong>Methods: </strong>Nine online databases were searched: China National Knowledge Infrastructure, China Science and Technology Journal Database, Wanfang Data Knowledge Service Platform, Chinese BioMedical Literature Database, China Clinical Trial Centre, Embase, PubMed, the Cochrane Library, and Web of Science. The search period was from the establishment of the database to 1 September 2023. The quality of the literature was evaluated using the Cochrane Risk of Bias Assessment Tool, and the data were analyzed using STATA/MP17 and Review Manager 5.3 software.</p><p><strong>Results: </strong>A total of 221 articles were identified, and 13 studies were included. The total sample size was 899, including 452 and 447 cases in the experimental and control groups, respectively. The meta-analysis showed that acupuncture combined with modern medical treatment was effective in improving urinary albumin excretion rate, 24 h urinary microalbumin, serum creatinine, blood urea nitrogen, fasting plasma glucose, 2 h post-prandial plasma glucose, total cholesterol, high-density lipoprotein cholesterol, hypersensitive C-reactive protein, and interleukin-6 in patients with DN. Adverse events were reported in only one trial; therefore, this review cannot yet conclude on the safety of acupuncture intervention in DN.</p><p><strong>Conclusion: </strong>The clinical efficacy of acupuncture combined with modern medicine in DN is superior to that of modern medicine alone. To better evaluate the efficacy and safety of acupuncture intervention for DN, more rigorously designed large-sample, multicentre, randomized controlled trials are needed to provide evidence support in the future.</p>","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"53 11","pages":"2404-2418"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Osteocalcin in Patients with Osteoporosis: A Systematic Review. 骨钙素在骨质疏松患者中的作用:一项系统综述。
IF 1.4 4区 医学 Q3 Medicine Pub Date : 2024-11-01 DOI: 10.18502/ijph.v53i11.16945
Seyed Mohammad Mohammadi, Nadia Saniee, Sajedeh Mousaviasl, Esmat Radmanesh, Amir Hossein Doustimotlagh

Background: Osteoporosis is the most common systemic skeletal disease worldwide. We aimed to review the latest studies related to osteocalcin and osteoporosis to clarify this relationship more precisely.

Methods: A systematic literature search was performed to review studies on the effects of osteocalcin on osteoporosis, on studied published between January 2013 and January 2023. We systematically reviewed Web of Science, PubMed, ProQuest, Scopus, and Google Scholar.

Results: The search yielded 4903 records, including 1063 from PubMed, 2307 from Scopus, 1084 from Web of Science, 408 from ProQuest, and 41 from Google Scholar, and twelve articles were included for data extraction and quality assessment. A significant increase in the serum level of osteocalcin was observed in postmenopausal women with osteoporosis (P<0.05), and there was a negative correlation between bone mineral density and the serum level of osteocalcin.

Conclusion: Osteocalcin could be a promising marker for the diagnosis and screening of patients with osteoporosis.

背景:骨质疏松症是世界范围内最常见的系统性骨骼疾病。我们旨在回顾有关骨钙素和骨质疏松症的最新研究,以更准确地阐明这种关系。方法:系统检索2013年1月至2023年1月间发表的关于骨钙素治疗骨质疏松的文献。我们系统地回顾了Web of Science、PubMed、ProQuest、Scopus和谷歌Scholar。结果:共检索到4903条记录,其中PubMed检索1063条,Scopus检索2307条,Web of Science检索1084条,ProQuest检索408条,b谷歌Scholar检索41条,共纳入12篇文章进行数据提取和质量评估。绝经后骨质疏松症患者血清骨钙素水平明显升高(结论:骨钙素可作为骨质疏松症的诊断和筛查指标。
{"title":"The Role of Osteocalcin in Patients with Osteoporosis: A Systematic Review.","authors":"Seyed Mohammad Mohammadi, Nadia Saniee, Sajedeh Mousaviasl, Esmat Radmanesh, Amir Hossein Doustimotlagh","doi":"10.18502/ijph.v53i11.16945","DOIUrl":"https://doi.org/10.18502/ijph.v53i11.16945","url":null,"abstract":"<p><strong>Background: </strong>Osteoporosis is the most common systemic skeletal disease worldwide. We aimed to review the latest studies related to osteocalcin and osteoporosis to clarify this relationship more precisely.</p><p><strong>Methods: </strong>A systematic literature search was performed to review studies on the effects of osteocalcin on osteoporosis, on studied published between January 2013 and January 2023. We systematically reviewed Web of Science, PubMed, ProQuest, Scopus, and Google Scholar.</p><p><strong>Results: </strong>The search yielded 4903 records, including 1063 from PubMed, 2307 from Scopus, 1084 from Web of Science, 408 from ProQuest, and 41 from Google Scholar, and twelve articles were included for data extraction and quality assessment. A significant increase in the serum level of osteocalcin was observed in postmenopausal women with osteoporosis (<i>P</i><0.05), and there was a negative correlation between bone mineral density and the serum level of osteocalcin.</p><p><strong>Conclusion: </strong>Osteocalcin could be a promising marker for the diagnosis and screening of patients with osteoporosis.</p>","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"53 11","pages":"2432-2439"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Iranian Journal of Public Health
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