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JACC. Cardiovascular interventions最新文献

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IF 11.4 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-12 DOI: 10.1016/S1936-8798(25)03221-2
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引用次数: 0
PRODIGY Reclassification May Alter the Meta-Analytical Results on Aspirin vs P2Y12 Inhibitor Monotherapy After Short DAPT PRODIGY重新分类可能会改变短期DAPT后阿司匹林与P2Y12抑制剂单药治疗的meta分析结果
IF 11.4 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-12 DOI: 10.1016/j.jcin.2025.09.051
Grzegorz Procyk MD , Kamil Tkacz
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引用次数: 0
Long-Term Outcomes After Melody Transcatheter Pulmonary Valve Implant in Patients Weighing ≤30 kg 体重≤30kg患者经导管肺动脉瓣置入术后的远期疗效
IF 11.4 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-12 DOI: 10.1016/j.jcin.2025.10.049
Elisa K. McCarthy MD , Stanimir Georgiev MD , Yulin Zhang PhD , Matthew E. Boucek MD , Kirby C. Johnson , Ayush Jaggi MPH , Daniel S. Levi MD , Lynn F. Peng MD , Mary Hunt Martin MD , Brian H. Morray MD , Athar M. Qureshi MD , Alejandro J. Torres MD , Allison K. Cabalka MD , Holly Bauser-Heaton MD, PhD , Felix Berger MD , Peter Ewert MD , Doff B. McElhinney MD

Background

Small multicenter studies have shown that transcatheter pulmonary valve replacement (TPVR) can be performed with good procedural and early hemodynamic results in patients weighing <30 kg; little is known about longer term outcomes.

Objectives

The aim of this study was to characterize long-term outcomes after Melody valve placement in patients weighing ≤30 kg.

Methods

Selected centers participating in prior registry studies provided updated outcome data.

Results

Between April 2009 and April 2019, 199 patients weighing ≤30kg underwent successful Melody valve placement across 10 centers. During a median follow-up period of nearly 8 years, 78 patients underwent initial reintervention with balloon dilation (n = 20), transcatheter valve-in-valve (n = 30), or explantation (n = 28). Among patients who had not undergone reintervention, 81% of those with available echocardiograms had good valve function. Thirty-two patients developed endocarditis, 20 with predisposing factors; 9 were managed medically. Estimated freedom from pulmonary valve reintervention at 10 years was 46% (95% CI: 36%-55%). On age- and weight-adjusted multivariable Cox regression, right ventricular systolic pressure immediately after implantation (HR: 1.03; 95% CI: 1.00-1.05; P = 0.026) was associated with freedom from reintervention. Freedom from Melody valve explantation at 10 years was 78% (95% CI: 69%-85%), and freedom from endocarditis was 79% (95% CI: 71%-86%). These outcomes did not vary significantly according to weight, delivery system, or era of implantation.

Conclusions

In this large multicenter study, longer term survival and freedom from reintervention or explantation after TPVR were similar to previously reported data for small patients with a surgical pulmonary conduit or bioprosthetic valve. These findings support the utility of TPVR with a Melody valve for delaying surgical valve replacement in small patients.
背景:小型多中心研究表明,在体重30 kg的患者中,经导管肺瓣膜置换术(TPVR)可以获得良好的程序和早期血流动力学结果。人们对长期结果知之甚少。目的本研究的目的是描述体重≤30kg的患者置放Melody瓣膜后的长期预后。方法选择参与先前注册研究的中心提供最新的结果数据。结果2009年4月至2019年4月,199名体重≤30kg的患者在10个中心成功进行了Melody瓣膜置换术。在近8年的中位随访期间,78例患者接受了球囊扩张(n = 20)、经导管瓣内置换术(n = 30)或外植术(n = 28)的初始再干预。在未接受再干预的患者中,超声心动图显示81%的患者瓣膜功能良好。32例发生心内膜炎,20例有易感因素;9人接受医疗处理。估计10年后肺动脉瓣再介入的自由度为46% (95% CI: 36%-55%)。经年龄和体重调整的多变量Cox回归分析,植入后立即右心室收缩压(HR: 1.03; 95% CI: 1.00-1.05; P = 0.026)与再次干预自由相关。10年后梅洛迪瓣膜外植的自由率为78% (95% CI: 69%-85%),心内膜炎的自由率为79% (95% CI: 71%-86%)。这些结果没有因体重、输送系统或植入时间的不同而有显著差异。结论:在这项大型多中心研究中,TPVR术后的长期生存率和再次干预或移植的自由度与先前报道的小患者手术肺导管或生物假瓣膜的数据相似。这些发现支持TPVR与Melody瓣膜在小患者延迟手术瓣膜置换术中的应用。
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引用次数: 0
Conflict of Interest Among Journal Authors 期刊作者的利益冲突
IF 11.4 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-12 DOI: 10.1016/j.jcin.2025.10.048
Christopher J. White MD (Associate Editor, JACC: Cardiovascular Interventions)
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引用次数: 0
Impact of Repeated Drug-Coated Balloon for Restenosis Following Femoropopliteal Drug-Coated Balloon Treatment 反复药物包被球囊治疗股腘动脉再狭窄的影响
IF 11.4 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-12 DOI: 10.1016/j.jcin.2025.10.043
Yoshimitsu Soga MD, PhD , Mitsuyoshi Takahara MD, PhD , Osamu Iida MD, PhD , Yusuke Tomoi MD , Daizo Kawasaki MD, PhD , Akiko Tanaka MD , Yasutaka Yamauchi MD, PhD , Kazuki Tobita MD , Amane Kozuki MD, PhD , Masahiko Fujihara MD , OYSTER Investigators
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引用次数: 0
Mind the Gap! 小心缝隙!
IF 11.4 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-12 DOI: 10.1016/j.jcin.2025.10.061
Mara Pilati MD , Fabiola Boccuto MD , Claudia Montanaro MD , Paolo Ciancarella MD , Gianfranco Butera MD
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引用次数: 0
Percutaneous Papillary Muscle Banding to Reshape Failing Left Ventricle 经皮乳头肌束带重塑衰竭左心室
IF 11.4 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-12 DOI: 10.1016/j.jcin.2025.10.047
Piotr Musialek MD, DPhil , Lukasz Tekieli MD, PhD , Adam Mazurek MD, PhD , Lukasz Czyz MD , Jakub Chmiel MD , Krzysztof Bartus MD, PhD , R. Pawel Banys MSc (Eng) , Joanna Szachowicz-Jaworska MD , Jacek Piatek MD, PhD , Andrzej Gackowski MD, PhD
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引用次数: 0
Stress Hyperglycemia Should Not Be Confused With Diabetes Mellitus 应激性高血糖不应与糖尿病混淆
IF 11.4 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-12 DOI: 10.1016/j.jcin.2025.04.052
Hao Yang MM, Jieyi Wang MD, Aisong Zhu MD
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引用次数: 0
OCT-Guided Clues OCT-Guided线索
IF 11.4 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-12 DOI: 10.1016/j.jcin.2025.05.048
Ioannis Skalidis MD, PhD, Thierry Unterseeh MD, Pietro Laforgia MD, Stephane Chapagne MD, Nicolas Amabile MD, PhD
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引用次数: 0
Pursuit of State-of-the-Art PCI With Imaging and Physiology 追求最先进的PCI成像和生理学
IF 11.4 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2026-01-12 DOI: 10.1016/j.jcin.2025.11.006
Edward T. Ha MD , Tatsunori Takahashi MD , Yuhei Kobayashi MD
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引用次数: 0
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JACC. Cardiovascular interventions
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