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A Mathematical Modeling of the Vaccination Effect on the SARS-CoV-2 Transmission: Analysis and Simulation 疫苗接种对 SARS-CoV-2 传播影响的数学建模:分析与模拟
Q4 Earth and Planetary Sciences Pub Date : 2024-03-29 DOI: 10.24996/ijs.2024.65.3.31
Rami Raad Saadi, H. Al-Husseiny
     Several illustrative studies on the mathematical modeling and analysis of the Coronavirus have been carried out in a short period of time. There is not enough work that accounts for the vaccination campaign's two stages. In this work, a mathematical model is created to show the impact of the recent two-stage vaccination treatment on the Coronavirus. In the proposed model, five compartments are constructed, namely the susceptible individuals , the first dose of vaccination  , the second dose of vaccination , infected  and recovered population . The uniqueness, boundedness and existence of the solutions of this model have been discussed. All potential model equilibrium points are determined. The local as well as global stability of the system in terms of the basic reproduction number is investigated. Numerical simulation is also carried out to investigate the influence of parameters affecting the dynamics of the model and to support the gathered analytical findings of the model.
在很短的时间内,就冠状病毒的数学建模和分析开展了多项说明性研究。但对疫苗接种活动的两个阶段进行说明的工作还不够多。在这项工作中,建立了一个数学模型,以显示最近的两阶段疫苗接种处理对冠状病毒的影响。在提议的模型中,构建了五个分区,即易感个体、第一剂疫苗接种、第二剂疫苗接种、感染人群和康复人群。讨论了该模型解的唯一性、有界性和存在性。确定了所有潜在的模型平衡点。研究了系统在基本繁殖数方面的局部和全局稳定性。此外,还进行了数值模拟,以研究影响模型动态的参数的影响,并为收集到的模型分析结果提供支持。
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引用次数: 0
Involvement of Total Antioxidant Activity and eNOS Gene rs1799983/ rs2070744 Polymorphisms in Breast Carcinogenesis 总抗氧化活性和 eNOS 基因 rs1799983/ rs2070744 多态性与乳腺癌发病的关系
Q4 Earth and Planetary Sciences Pub Date : 2024-03-29 DOI: 10.24996/ijs.2024.65.3.11
Istikrar Hade, Ahmed S. K. Al-Khafaji, F. Lafta
     Globally, breast cancer is the common malignancy affecting women and understanding its associated molecular events could help in disease prevention and management strategies. The present study was set to investigate an association between total antioxidant capacity (TAC) and endothelial nitric oxide synthase (eNOS) polymorphisms with breast cancer. For this purpose, 100 subjects were participated in this work, including 50 female patients diagnosed with breast cancer recruited from Oncology hospital, Baghdad - Iraq and 50 healthy women as a control group. The concentration of antioxidants was measured in the serums collected from blood samples of breast cancer patients and healthy controls. While eNOS SNPs (rs1799983, G894T and rs2070744, T 786C) were assessed using TaqMan SNP genotyping and utilising genomic DNA extracted from the participants. The results showed that the antioxidants levels were significantly (P˂0.0001) reduced in blood samples of breast cancer patients in comparison to that of that healthy controls (0.144± 0.097 and 0.587±0.239 respectively). Additionally, the homozygous GG genotype G894T (rs1799983) could retain beneficial impact for the protection from breast cancer potential. While SNP genotyping results showed that both of the homozygous CC and heterozygous TC genotypes (rs2070744 T >C SNP) seem to contribute to the susceptibility of breast cancer development in the investigated set of patients. Overall, the present study findings suggest an association between reduced antioxidant capacity and eNOS gene polymorphisms in breast carcinogenesis.
在全球范围内,乳腺癌是影响女性的常见恶性肿瘤,了解其相关的分子事件有助于制定疾病预防和管理策略。本研究旨在探讨总抗氧化能力(TAC)和内皮一氧化氮合酶(eNOS)多态性与乳腺癌的关系。为此,100 名受试者参与了这项研究,其中包括从伊拉克巴格达肿瘤医院招募的 50 名确诊为乳腺癌的女性患者,以及 50 名健康女性作为对照组。从乳腺癌患者和健康对照组血液样本中采集的血清中测量了抗氧化剂的浓度。而 eNOS SNPs(rs1799983,G894T 和 rs2070744,T 786C)则是利用 TaqMan SNP 基因分型技术和从参与者身上提取的基因组 DNA 进行评估的。结果显示,与健康对照组相比,乳腺癌患者血液样本中的抗氧化剂水平明显降低(P˂0.0001)(分别为 0.144±0.097 和 0.587±0.239)。此外,同源 GG 基因型 G894T(rs1799983)对乳腺癌的潜在保护仍有益处。SNP基因分型结果显示,同源CC基因型和杂合TC基因型(rs2070744 T >C SNP)似乎都会导致所调查的患者易患乳腺癌。总之,本研究结果表明,抗氧化能力降低与 eNOS 基因多态性在乳腺癌发生中存在关联。
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引用次数: 0
Evaluating the Performance and Behavior of CNN, LSTM, and GRU for Classification and Prediction Tasks 评估 CNN、LSTM 和 GRU 在分类和预测任务中的性能和行为
Q4 Earth and Planetary Sciences Pub Date : 2024-03-29 DOI: 10.24996/ijs.2024.65.3.43
Hasanen S. Abdullah, Nada Hussain Ali, Nada A. Z. Abdullah
     Deep learning (DL) plays a significant role in several tasks, especially classification and prediction. Classification tasks can be efficiently achieved via convolutional neural networks (CNN) with a huge dataset, while recurrent neural networks (RNN) can perform prediction tasks due to their ability to remember time series data. In this paper, three models have been proposed to certify the evaluation track for classification and prediction tasks associated with four datasets (two for each task). These models are CNN and RNN, which include two models (Long Short Term Memory (LSTM)) and GRU (Gated Recurrent Unit). Each model is employed to work consequently over the two mentioned tasks to draw a road map of deep learning models for a variety of tasks under the control of a unified architecture for each proposed model.
深度学习(DL)在多项任务中发挥着重要作用,尤其是分类和预测。分类任务可以通过卷积神经网络(CNN)与庞大的数据集有效地实现,而循环神经网络(RNN)由于具有记忆时间序列数据的能力,可以执行预测任务。本文提出了三种模型,以认证与四个数据集(每个任务两个数据集)相关的分类和预测任务的评估轨迹。这些模型是 CNN 和 RNN,其中包括两个模型(长短期记忆(LSTM))和 GRU(门控循环单元)。每个模型都被用于上述两个任务的相应工作,以便在每个拟议模型的统一架构控制下,为各种任务绘制深度学习模型路线图。
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引用次数: 0
Characterization of P-Semi Homogeneous System of Difference Equations of Three dimension 三维 P 半均质差分方程组的特征
Q4 Earth and Planetary Sciences Pub Date : 2024-03-29 DOI: 10.24996/ijs.2024.65.3.23
Abdul Samad Ibrahim Hussein, B. Al-Asadi
     The aim of this paper is to define new concepts, namely a homogenous system of difference equations x(n+1)=Bx(n)  where  B is a matrix of real numbers, which is called P-semi homogenous of order m if there exists a non-zero matrix A and integer number m such that the following equation holds: F (A(c)x(n))= 〖P(A(c))〗^m F(x(n)), Where F is a function,  m and  P are integer numbers and c is a real number. This definition is a generalization to the (3×3)-semi-homogeneous system of difference equations of order m. Special cases are studied of this definition and illustrative examples are given and some characterizations of this definition are also given. The necessary and sufficient conditions for a homogenous system of difference Equations to be P-semi homogenous of order one or greater than one as well as some examples and theorems about there are given.
本文旨在定义新概念,即同质差分方程组 x(n+1)=Bx(n) (其中 B 是实数矩阵),如果存在非零矩阵 A 和整数 m,且下式成立,则该同质差分方程组称为阶数为 m 的 P 半同质差分方程组:F (A(c)x(n))=〖P(A(c))〗^m F(x(n)),其中 F 是函数,m 和 P 是整数,c 是实数。该定义是对 m 阶差分方程的 (3×3)-semi-homogeneous 系统的概括,研究了该定义的特例,并给出了示例,还给出了该定义的一些特征。给出了阶数为 1 或大于 1 的同质差分方程组是 P 半同质的必要条件和充分条件,以及有关的一些例子和定理。
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引用次数: 0
Water Quality Assessment of Tigris River Using Multivariate Statistical Techniques 利用多元统计技术评估底格里斯河水质
Q4 Earth and Planetary Sciences Pub Date : 2024-03-29 DOI: 10.24996/ijs.2024.65.3.8
Noor A.H. Alharbawee, Ahmed Jasim Mohammed
     Factor and cluster analysis, two multivariate statistical approaches, have been used to analyze temporal and spatial variations and pollutants sources effecting the water quality of Tigris River from the north to the south of Baghdad city. From October 2021 to September 2022, 15 water quality parameters (electrical conductivity (EC), pH, water temperature (WT), turbidity (Tur), total hardness (TH), biochemical Ooxygen Ddemand (BOD), dissolved oxygen (DO), Mg+, Ca+, SO4, dissolved solids (TDS), total suspended solids (TSS), total chlorine (TC), Cr, and Al) were tested at five monitoring sites (Balad, Al-Ghrai’at, Al-Shuhada'a Bridge, Al-Za’franiya, and Jisr Diyala), along the study area of the river. Results revealed that the major factor that affects the water quality in the study area is the anthropogenic factor. Spatial cluster analysis of the monitoring sites revealed three different groups that were compared to one another where each site suggested a different degree of contamination in the Tigris river water quality.
采用因子分析和聚类分析这两种多元统计方法,分析了影响巴格达市南至北底格里斯河水质的时空变化和污染物来源。从 2021 年 10 月到 2022 年 9 月,15 个水质参数(电导率 (EC)、pH 值、水温 (WT)、浊度 (Tur)、总硬度 (TH)、生化需氧量 (BOD)、溶解氧 (DO)、Mg+、Ca+、SO4、在沿河研究区域的五个监测点(巴拉德、Al-Ghrai'at、Al-Shuhada'a Bridge、Al-Za'franiya 和 Jisr Diyala)检测了溶解固体 (TDS)、总悬浮固体 (TSS)、总氯 (TC)、铬和铝。结果显示,影响研究区域水质的主要因素是人为因素。对监测点进行空间聚类分析后发现,有三个不同的组别,通过相互比较,每个组别都表明底格里斯河水质受到不同程度的污染。
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引用次数: 0
An Analytic Model for COVID-19 Cases in Iran and Its Neighbors Using Deep Learning and Time Series Methods 利用深度学习和时间序列方法建立伊朗及其邻国 COVID-19 病例分析模型
Q4 Earth and Planetary Sciences Pub Date : 2024-03-29 DOI: 10.24996/ijs.2024.65.3.36
Razieyeh Abedi, Kheirolah Rahsepar Frad
     Since the pandemic of the coronavirus (COVID-19) in 2019, it has rapidly become a major global health concern. Various mutations and rapid spread of the virus, a lack of specific treatment, and limited hospital facilities highlight the importance of anticipation, risk analysis, and timely treatment. The use of mathematical models, artificial intelligence, and simulation methods are effective tools in predicting the spread and providing effective solutions to prevent virus transmission. Analysis and forecasting require an integrated model to cover different aspects of the problem and use different methods to obtain appropriate results.   In this research, a proposed model for analysis and prediction of COVID-19 cases in Iran and neighboring countries is presented. The performance of mathematical and deep learning models in the proposed model has been evaluated using data from Johns Hopkins University from January 29, 2020, to April 30, 2021. Evaluation of the predictive outcomes of daily cases was performed using RMSE criteria. Then, the effect of the trend of cases in neighboring countries of Iran on the rate of new cases in this country has been studied. These models can help governments predict the number of infections to provide the necessary solutions and prevent a new wave of the virus.
自 2019 年冠状病毒(COVID-19)大流行以来,它已迅速成为全球关注的主要健康问题。病毒的各种变异和快速传播、缺乏特效治疗方法、医院设施有限等问题凸显了预测、风险分析和及时治疗的重要性。使用数学模型、人工智能和模拟方法是预测病毒传播并提供有效解决方案以防止病毒传播的有效工具。分析和预测需要一个综合模型来涵盖问题的不同方面,并使用不同的方法来获得适当的结果。 本研究提出了一个用于分析和预测伊朗及其邻国 COVID-19 病例的模型。利用约翰-霍普金斯大学 2020 年 1 月 29 日至 2021 年 4 月 30 日的数据,对拟议模型中数学模型和深度学习模型的性能进行了评估。使用 RMSE 标准对每日病例的预测结果进行了评估。然后,研究了伊朗邻国的病例趋势对该国新病例发生率的影响。这些模型可以帮助政府预测感染人数,从而提供必要的解决方案,防止新一轮的病毒传播。
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引用次数: 0
Isolation and Identification of Shigella SonneiProducing Shiga Toxin from Children with Bloody Diarrhea and Evaluation of the Inhibition Effectiveness of Zinc oxide Nanoparticles 从血性腹泻儿童中分离和鉴定产生志贺毒素的宋内志贺菌并评估氧化锌纳米颗粒的抑制效果
Q4 Earth and Planetary Sciences Pub Date : 2024-03-29 DOI: 10.24996/ijs.2024.65.3.12
Hayfaa Rajab Alwan, S. Dahham, Ahmed Hussein Dhayea, Mohammad Nadhir Maaroof
     Shigella infection strains producing shiga toxin results in bloody diarrheais a dangerous symptom in children under five years of age that can even lead to death. Therefore, this study was conducted to isolate Shigella strains producing shiga toxin from 150 samples which were taken from bloody stool of children under the five years of age. They were suffering from the diarrhea during the period from March 2021 to March 2022 in Tikrit city, Iraq. The results showed the possibility to isolate six isolates of Shigella sonnei at ratio 4% of the total samples. The isolates producing shiga toxin were identified by using stx1 gene. The results showed two isolates of Shigella possessing stx1 gene, at ratio 33.33 of total S. sonnei strains. The two isolates producing shiga toxin have been submitted to NCBI, then accepted as Iraqi strains in NCBI under the registration numbers OK127759.1 and OK127760.1. The Iraqi strains registered in NCBI showed agreement with a global strain of 99-100%  that were recorded by registration numbers in Malaysia (CP060117.1), China (CP000038.1), United Kingdom (CP066810.1), Hungary (CP019689.1), Somalia (CP023645.1), Spain (CP022672.1), Italy (CP035008.1), India (CP041322.1), Australia (CP045932.1), Nigeria (CP046286.1), Switzerland (CP049183.1), USA (CP053751.1) and South Korea (CP055292.1). As for the sensitivity test, the results showed that the strain OK127759.1 was resistant to antibiotics azithromycin, ceftazidime, cefotaxime, ceftriaxone, augmentin and tetracycline. And it was sensitive to gentamicin and intermediately sensitive to ampicillin, chloramphenicol and nalidixic acid. As for the strain OK127760.1, the results showed his strain was intermediately sensitive to gentamicin and resistant to the other antibiotics which were used in the test. ZnO-NPs with a concentration of 200 μg/ml showed the highest inhibitory effectiveness against S. sonnei strains OK127759.1 and OK127760.1 with inhibition diameter of 22 mm and 21 mm respectively.
志贺氏菌感染产生志贺毒素的菌株会导致五岁以下儿童出现血性腹泻,这是一种危险的症状,甚至会导致死亡。因此,本研究从 150 份从五岁以下儿童血便中提取的样本中分离出产生志贺毒素的志贺氏杆菌菌株。这些儿童于 2021 年 3 月至 2022 年 3 月期间在伊拉克提克里特市腹泻。结果表明,可以分离出 6 个子内志贺氏菌分离株,占样本总数的 4%。利用 stx1 基因鉴定了产生志贺毒素的分离物。结果表明,有两株志贺氏菌分离物具有 stx1 基因,占 Sonnei 志贺氏菌菌株总数的 33.33%。这两个产生志贺毒素的分离株已提交给美国国家生物信息局,随后被美国国家生物信息局接纳为伊拉克菌株,登记号分别为 OK127759.1 和 OK127760.1。在 NCBI 登记的伊拉克菌株与全球菌株的吻合率为 99-100%,这些全球菌株的登记号分别记录在马来西亚(CP060117.1)、中国(CP000038.1)、英国(CP066810.1)、匈牙利(CP019689.1)、索马里(CP023645.1)、西班牙(CP022672.1)、意大利(CP035008.1)、印度(CP041322.1)、澳大利亚(CP045932.1)、尼日利亚(CP046286.1)、瑞士(CP049183.1)、美国(CP053751.1)和韩国(CP055292.1)。药敏试验结果表明,OK127759.1菌株对阿奇霉素、头孢他啶、头孢噻肟、头孢曲松、阿糖胞苷和四环素等抗生素耐药。它对庆大霉素敏感,对氨苄西林、氯霉素和萘啶酸中间敏感。至于 OK127760.1 菌株,结果显示该菌株对庆大霉素中度敏感,对试验中使用的其他抗生素具有抗药性。浓度为 200 μg/ml 的 ZnO-NPs 对 S. sonnei 菌株 OK127759.1 和 OK127760.1 的抑制效果最好,抑制直径分别为 22 毫米和 21 毫米。
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引用次数: 0
Verifying the Best Iraqi Area to Install a LOFAR Radio Telescope Using SWOT Model 利用 SWOT 模型验证安装 LOFAR 射电望远镜的最佳伊拉克地区
Q4 Earth and Planetary Sciences Pub Date : 2024-03-29 DOI: 10.24996/ijs.2024.65.3.44
Zina Fadel Kahdim, Kamal M. Abood
     Many of the radio telescope's wireless sensor networks operate outdoors, where changing weather might impact their system performance. Therefore, it is necessary to explore the climatic and topographic factors that affect the quality of the radio link to mitigate its impact and adapt to different conditions. In this study, the effects of the region's topography and climate on the strength of the radio signal were studied. Besides studying the effects of the soil of the area and land flatness on determining the optimal location for erecting a radio telescope in Iraq within four governorates (Nineveh, AL-Anbar, Al-Najaf, and Al-Muthanna). Data from relevant ministries and a digital map dataset for the area's topography with dimensions of 4 km x 6 km were used. The obtained results, via applying the SWOT model, showed that the best Iraqi area for erecting a radio telescope (LOFAR) among the selected regions according to the atmospheric parameters, such as air temperature, relative humidity, and wind speed, and other conditions such as transportation, the security component, number of buildings, population, and communication towers was Al- Muthanna governorate. It is considered the best radio zone for observing radio signals.
射电望远镜的许多无线传感器网络都在户外运行,不断变化的天气可能会影响其系统性能。因此,有必要探索影响无线电链路质量的气候和地形因素,以减轻其影响并适应不同的条件。在这项研究中,研究了该地区的地形和气候对无线电信号强度的影响。除了研究该地区的土壤和土地平整度对确定在伊拉克四个省(尼尼微省、安巴尔省、纳杰夫省和穆萨纳省)内架设射电望远镜的最佳位置的影响之外,还研究了该地区的地形和气候对射电信号强度的影响。使用了相关部委提供的数据和该地区地形数字地图数据集(尺寸为 4 千米 x 6 千米)。应用 SWOT 模型得出的结果表明,根据大气参数(如气温、相对湿度和风速)以及其他条件(如交通、安全因素、建筑物数量、人口和通信塔),在所选地区中最适合安装射电望远镜(LOFAR)的伊拉克地区是穆萨纳省。该地区被认为是观测无线电信号的最佳无线电区域。
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引用次数: 0
Isopach Map of Mishrif Formation in Nasiriya Oil Field by Using 3D Seismic Data 利用三维地震数据绘制 Nasiriya 油田 Mishrif 地层等深线图
Q4 Earth and Planetary Sciences Pub Date : 2024-03-29 DOI: 10.24996/ijs.2024.65.3.21
Yousif T. Habeeb, Kamal K. Ali
     The current study included interpretations of the three-dimensional seismic Data for the Nasiriya oil field implemented by the Oil exploration company in 2010 with a planned surface coverage area of 1273 km². The Nasiriyah field is located in southern Iraq within the Dhi Qar Governorate, about (10) km northwest of the governorate center (Nasiriyah), and the Muthanna governorate is located in the northwestern part of the field, which is approximately (15) km west of the governorate center (Samawah). The information from the wells (well velocity survey, formation depths, logs) was relied upon and entered into the seismic cube data to capture the top of the Mishrif Formation. In addition is to pick the top of the Rumaila Formation, which represents the bottom of the Mishrif Formation. The top and bottom Mishrif reflectors were picked, interpreted, and tracked within the region. The reflector's two-way time (TWT), velocity, and depth maps showed structural closure features in the center of the area, and the general direction of the closure is thenorthwest–southeast. The structural maps showed a general tendency towards the northeast. The isopach map showed that the thickness values of the Mishrif Formation increased to the west and northwest while the thickness decreased toward the east and southeast.
本次研究包括对石油勘探公司 2010 年实施的纳西里耶油田三维地震数据的解释,计划覆盖地表面积为 1273 平方公里。纳西里耶油田位于伊拉克南部泽卡尔省,距省中心(纳西里耶)西北约(10)公里,穆萨纳省位于油田西北部,距省中心(萨马瓦)以西约(15)公里。根据油井的信息(井速测量、地层深度、测井记录)并将其输入地震立方体数据,以捕捉 Mishrif 地层的顶部。此外,还选取了代表 Mishrif 地层底部的 Rumaila 地层顶部。在该区域内挑选、解释和跟踪了顶部和底部的 Mishrif 反射体。反射体的双向时间(TWT)、速度和深度图显示了该区域中心的构造闭合特征,闭合的大致方向为西北-东南。构造图显示总体倾向于东北方向。等深线图显示,Mishrif 地层的厚度值向西部和西北部增加,而向东部和东南部减少。
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引用次数: 0
Preserving Genotype Privacy Using AES and Partially Homomorphic Encryption 使用 AES 和部分同态加密技术保护基因型隐私
Q4 Earth and Planetary Sciences Pub Date : 2024-03-29 DOI: 10.24996/ijs.2024.65.3.38
Hiba M. Yousif, Sarab M. Hameed
     Increasingly, the availability of personal genomic data in cloud servers hosted by hospitals and research centers has incentivized researchers to turn to research that deals with analyzing genomic data. This is due to its importance in detecting diseases caused by genetic mutations, detecting genes that carry genetic diseases, and attempting to treat them in future generations.  Secure query execution on encrypted data is considered an active research area in which encryption is used to ensure the confidentiality of genomic data while restricting the ability to process such data without first decrypting it. To provide a secure framework and future insight into the potential contributions of homomorphic encryption to the field of genomic data, this paper proposes a framework for guaranteeing genomic data privacy using various partial homomorphic encryption techniques. By examining the characteristics of the three partial homomorphic encryptions based on different parameters. The framework has been online tested and compared based on different parameters. Three homomorphic encryption algorithms were adopted to ensure genomic data privacy by employing homomorphic operations in the query matching process. Experiments on real datasets, specifically MERS and SARSr-COV, showed that the proposed framework is efficient and improves query execution time by an average of 96% compared to existing work.
越来越多的个人基因组数据可以从医院和研究中心托管的云服务器中获取,这促使研究人员转向分析基因组数据的研究。这是因为基因组数据在检测基因突变引起的疾病、检测携带遗传疾病的基因以及试图为后代治疗这些疾病方面非常重要。 在加密数据上安全执行查询被认为是一个活跃的研究领域,在这个领域中,加密被用来确保基因组数据的机密性,同时限制在未解密的情况下处理这些数据的能力。为了提供一个安全的框架并深入了解同态加密对基因组数据领域的潜在贡献,本文提出了一个使用各种部分同态加密技术保证基因组数据隐私的框架。通过研究基于不同参数的三种部分同态加密技术的特点。根据不同参数对该框架进行了在线测试和比较。采用三种同态加密算法,通过在查询匹配过程中使用同态操作来确保基因组数据隐私。在真实数据集(特别是 MERS 和 SARSr-COV)上进行的实验表明,所提出的框架非常高效,与现有工作相比,查询执行时间平均缩短了 96%。
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引用次数: 0
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Iraqi Journal of Science
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