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Improvement and Maintenance of Clinical Outcomes in a Digital Mental Health Platform: Findings From a Longitudinal Observational Real-World Study. 数字心理健康平台中临床结果的改善与维持:一项纵向观察性真实世界研究的结果。
IF 5.4 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-06-24 DOI: 10.2196/48298
Lydia G Roos, Sara J Sagui-Henson, Cynthia Castro Sweet, Camille E Welcome Chamberlain, Brooke J Smith
<p><strong>Background: </strong>Digital mental health services are increasingly being provided by employers as health benefit programs that can improve access to and remove barriers to mental health care. Stratified care models, in particular, offer personalized care recommendations that can offer clinically effective interventions while conserving resources. Nonetheless, clinical evaluation is needed to understand their benefits for mental health and their use in a real-world setting.</p><p><strong>Objective: </strong>This study aimed to examine the changes in clinical outcomes (ie, depressive and anxiety symptoms and well-being) and to evaluate the use of stratified blended care among members of an employer-sponsored digital mental health benefit.</p><p><strong>Methods: </strong>In a large prospective observational study, we examined the changes in depressive symptoms (9-item Patient Health Questionnaire), anxiety symptoms (7-item Generalized Anxiety Disorder scale), and well-being (5-item World Health Organization Well-Being Index) for 3 months in 509 participants (mean age 33.9, SD 8.7 years; women: n=312, 61.3%; men: n=175, 34.4%; nonbinary: n=22, 4.3%) who were newly enrolled and engaged in care with an employer-sponsored digital mental health platform (Modern Health Inc). We also investigated the extent to which participants followed the recommendations provided to them through a stratified blended care model.</p><p><strong>Results: </strong>Participants with elevated baseline symptoms of depression and anxiety exhibited significant symptom improvements, with a 37% score improvement in depression and a 29% score improvement in anxiety (P values <.001). Participants with baseline scores indicative of poorer well-being also improved over the study period (90% score improvement; P=.002). Furthermore, over half exhibited clinical improvement or recovery for depressive symptoms (n=122, 65.2%), anxiety symptoms (n=127, 59.1%), and low well-being (n=82, 64.6%). Among participants with mild or no baseline symptoms, we found high rates of maintenance for low depressive (n=297, 92.2%) and anxiety (n=255, 86.7%) symptoms and high well-being (n=344, 90.1%). In total, two-thirds of the participants (n=343, 67.4%) used their recommended care, 16.9% (n=86) intensified their care beyond their initial recommendation, and 15.7% (n=80) of participants underused care by not engaging with the highest level of care recommended to them.</p><p><strong>Conclusions: </strong>Participants with elevated baseline depressive or anxiety symptoms improved their mental health significantly from baseline to follow-up, and most participants without symptoms or with mild symptoms at baseline maintained their mental health over time. In addition, engagement patterns indicate that the stratified blended care model was efficient in matching individuals with the most effective and least costly care while also allowing them to self-determine their care and use combinations of ser
背景介绍数字心理健康服务作为一项健康福利计划,越来越多地由雇主提供,它可以改善心理健康护理的可及性并消除障碍。分层护理模式尤其能提供个性化的护理建议,在节约资源的同时提供临床有效的干预措施。然而,要了解这些模式对心理健康的益处以及在实际环境中的应用,还需要进行临床评估:本研究旨在检查临床结果(即抑郁和焦虑症状及幸福感)的变化,并评估分层混合护理在雇主赞助的数字心理健康福利成员中的使用情况:在一项大型前瞻性观察研究中,我们对 509 名参与者(平均年龄 33.9, SD 8.7 years; women: n=312, 61.3%; men: n=175, 34.4%; nonbinary: n=22, 4.3%),他们新注册并参与了雇主赞助的数字心理健康平台(Modern Health Inc)的护理。我们还调查了参与者在多大程度上遵循了通过分层混合护理模式向他们提供的建议:结果:基线抑郁和焦虑症状升高的参与者症状明显改善,抑郁得分提高了 37%,焦虑得分提高了 29%(P 值 结论:基线抑郁和焦虑症状升高的参与者症状明显改善,抑郁得分提高了 37%,焦虑得分提高了 29%:基线抑郁或焦虑症状升高的参与者从基线到随访期间的心理健康状况都有明显改善,大多数没有症状或基线症状轻微的参与者随着时间的推移保持了心理健康。此外,参与模式表明,分层混合护理模式能够有效地为个人匹配最有效、成本最低的护理服务,同时也允许他们自主决定护理服务,并使用最适合其需求的服务组合。总之,本研究的结果证明了该平台在改善和保护心理健康方面的临床有效性,并支持分层混合护理模式在改善数字心理健康服务的获取和使用方面的实用性和有效性。
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引用次数: 0
Medical Information Protection in Internet Hospital Apps in China: Scale Development and Content Analysis. 中国互联网医院应用程序中的医疗信息保护:量表开发与内容分析
IF 5.4 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-06-21 DOI: 10.2196/55061
Jiayi Jiang, Zexing Zheng

Background: Hospital apps are increasingly being adopted in many countries, especially since the start of the COVID-19 pandemic. Web-based hospitals can provide valuable medical services and enhanced accessibility. However, increasing concerns about personal information (PI) and strict legal compliance requirements necessitate privacy assessments for these platforms. Guided by the theory of contextual integrity, this study investigates the regulatory compliance of privacy policies for internet hospital apps in the mainland of China.

Objective: In this paper, we aim to evaluate the regulatory compliance of privacy policies of internet hospital apps in the mainland of China and offer recommendations for improvement.

Methods: We obtained 59 internet hospital apps on November 7, 2023, and reviewed 52 privacy policies available between November 8 and 23, 2023. We developed a 3-level indicator scale based on the information processing activities, as stipulated in relevant regulations. The scale comprised 7 level-1 indicators, 26 level-2 indicators, and 70 level-3 indicators.

Results: The mean compliance score of the 52 assessed apps was 73/100 (SD 22.4%), revealing a varied spectrum of compliance. Sensitive PI protection compliance (mean 73.9%, SD 24.2%) lagged behind general PI protection (mean 90.4%, SD 14.7%), with only 12 apps requiring separate consent for processing sensitive PI (mean 73.9%, SD 24.2%). Although most apps (n=41, 79%) committed to supervising subcontractors, only a quarter (n=13, 25%) required users' explicit consent for subcontracting activities. Concerning PI storage security (mean 71.2%, SD 29.3%) and incident management (mean 71.8%, SD 36.6%), half of the assessed apps (n=27, 52%) committed to bear corresponding legal responsibility, whereas fewer than half (n=24, 46%) specified the security level obtained. Most privacy policies stated the PI retention period (n=40, 77%) and instances of PI deletion or anonymization (n=41, 79%), but fewer (n=20, 38.5%) committed to prompt third-party PI deletion. Most apps delineated various individual rights, but only a fraction addressed the rights to obtain copies (n=22, 42%) or to refuse advertisement based on automated decision-making (n=13, 25%). Significant deficiencies remained in regular compliance audits (mean 11.5%, SD 37.8%), impact assessments (mean 13.5%, SD 15.2%), and PI officer disclosure (mean 48.1%, SD 49.3%).

Conclusions: Our analysis revealed both strengths and significant shortcomings in the compliance of internet hospital apps' privacy policies with relevant regulations. As China continues to implement internet hospital apps, it should ensure the informed consent of users for PI processing activities, enhance compliance levels of relevant privacy policies, and fortify PI protection enforcement across the information processing stages.

背景:许多国家越来越多地采用医院应用程序,尤其是在 COVID-19 大流行开始之后。基于网络的医院可以提供有价值的医疗服务并提高可及性。然而,对个人信息(PI)的日益关注和严格的法律合规性要求使得有必要对这些平台进行隐私评估。本研究以情境完整性理论为指导,调查了中国大陆互联网医院应用程序隐私政策的合规性:本文旨在评估中国大陆互联网医院应用程序隐私政策的合规性,并提出改进建议:方法:我们于2023年11月7日获取了59款互联网医院APP,并对其中52款APP在2023年11月8日至23日期间的隐私政策进行了审查。根据相关法规的规定,我们根据信息处理活动制定了一个三级指标量表。该量表包括 7 个一级指标、26 个二级指标和 70 个三级指标:结果:52 个接受评估的应用程序的平均合规分数为 73/100(标准差 22.4%),合规程度参差不齐。敏感个人信息保护合规性(平均 73.9%,标准差 24.2%)落后于一般个人信息保护(平均 90.4%,标准差 14.7%),只有 12 款应用程序在处理敏感个人信息时需要单独征得同意(平均 73.9%,标准差 24.2%)。虽然大多数应用程序(n=41,79%)承诺监督分包商,但只有四分之一(n=13,25%)的分包活动需要用户明确同意。关于个人信息存储安全(平均 71.2%,标定值 29.3%)和事件管理(平均 71.8%,标定值 36.6%),半数受评应用程序(n=27,52%)承诺承担相应的法律责任,但只有不到半数(n=24,46%)明确说明了所获得的安全级别。大多数隐私政策说明了个人信息的保留期限(n=40,77%)和个人信息删除或匿名化的情况(n=41,79%),但承诺及时删除第三方个人信息的应用程序较少(n=20,38.5%)。大多数应用程序规定了各种个人权利,但只有一小部分涉及获取副本的权利(n=22,42%)或拒绝基于自动决策的广告的权利(n=13,25%)。在定期合规性审核(平均 11.5%,标准差 37.8%)、影响评估(平均 13.5%,标准差 15.2%)和 PI 官员披露(平均 48.1%,标准差 49.3%)方面仍存在重大缺陷:我们的分析显示,互联网医院应用程序的隐私政策在遵守相关法规方面既有优势,也存在明显不足。随着中国互联网医院应用程序的不断发展,应确保用户对隐私保护处理活动的知情同意,提高相关隐私政策的合规水平,并在信息处理的各个阶段加强隐私保护的执行力度。
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引用次数: 0
Effectiveness of a Multifaceted Mobile Health Intervention (Multi-Aid-Package) in Medication Adherence and Treatment Outcomes Among Patients With Hypertension in a Low- to Middle-Income Country: Randomized Controlled Trial. 中低收入国家高血压患者的用药依从性和治疗效果的多方面移动医疗干预措施(多辅助包)的效果:随机对照试验》。
IF 5.4 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-06-19 DOI: 10.2196/50248
Muhammad Arshed, Aidalina Mahmud, Halimatus Sakdiah Minhat, Poh Ying Lim, Rubeena Zakar
<p><strong>Background: </strong>The high prevalence of uncontrolled hypertension in Pakistan is predominantly attributed to poor medication adherence. As more than 137 million people in Pakistan use cell phones, a suitable mobile health (mHealth) intervention can be an effective tool to overcome poor medication adherence.</p><p><strong>Objective: </strong>We sought to determine whether a novel mHealth intervention is useful in enhancing antihypertensive therapy adherence and treatment outcomes among patients with hypertension in a low- to middle-income country.</p><p><strong>Methods: </strong>A 6-month parallel, single-blinded, superiority randomized controlled trial recruited 439 patients with hypertension with poor adherence to antihypertensive therapy and access to smartphones. An innovative, multifaceted mHealth intervention (Multi-Aid-Package), based on the Health Belief Model and containing reminders (written, audio, visual), infographics, video clips, educational content, and 24/7 individual support, was developed for the intervention group; the control group received standard care. The primary outcome was self-reported medication adherence measured using the Self-Efficacy for Appropriate Medication Adherence Scale (SEAMS) and pill counting; the secondary outcome was systolic blood pressure (SBP) change. Both outcomes were evaluated at baseline and 6 months. Technology acceptance feedback was also assessed at the end of the study. A generalized estimating equation was used to control the covariates associated with the probability of affecting adherence to antihypertensive medication.</p><p><strong>Results: </strong>Of 439 participants, 423 (96.4%) completed the study. At 6 months post intervention, the median SEAMS score was statistically significantly higher in the intervention group compared to the controls (median 32, IQR 11 vs median 21, IQR 6; U=10,490, P<.001). Within the intervention group, there was an increase in the median SEAMS score by 12.5 points between baseline and 6 months (median 19.5, IQR 5 vs median 32, IQR 11; P<.001). Results of the pill-counting method showed an increase in adherent patients in the intervention group compared to the controls (83/220, 37.2% vs 2/219, 0.9%; P<.001), as well as within the intervention group (difference of n=83, 37.2% of patients, baseline vs 6 months; P<.001). There was a statistically significant difference in the SBP of 7 mmHg between the intervention and control groups (P<.001) at 6 months, a 4 mmHg reduction (P<.001) within the intervention group, and a 3 mmHg increase (P=.314) within the controls. Overall, the number of patients with uncontrolled hypertension decreased by 46 in the intervention group (baseline vs 6 months), but the control group remained unchanged. The variables groups (adjusted odds ratio [AOR] 1.714, 95% CI 2.387-3.825), time (AOR 1.837, 95% CI 1.625-2.754), and age (AOR 1.618, 95% CI 0.225-1.699) significantly contributed (P<.001) to medication adherence. Multi-A
背景:巴基斯坦未得到控制的高血压发病率高,主要原因是服药依从性差。由于巴基斯坦有超过 1.37 亿人使用手机,因此合适的移动医疗(mHealth)干预措施可以成为克服用药依从性差的有效工具:我们试图确定一种新型移动医疗干预措施是否有助于提高中低收入国家高血压患者的降压治疗依从性和治疗效果:一项为期6个月的平行、单盲、优势随机对照试验招募了439名高血压患者,这些患者的降压治疗依从性较差,且无法使用智能手机。为干预组开发了基于健康信念模型的创新型、多方面移动医疗干预措施(多辅助包),其中包括提醒(书面、音频、视频)、信息图表、视频剪辑、教育内容和全天候个人支持;对照组接受标准护理。主要结果是自我报告的服药依从性,采用适当服药依从性自我效能量表(SEAMS)和药片计数进行测量;次要结果是收缩压(SBP)变化。这两项结果均在基线和 6 个月时进行评估。研究结束时还对技术接受反馈进行了评估。研究采用了广义估计方程来控制与影响降压药物依从性的概率相关的协变量:在 439 名参与者中,423 人(96.4%)完成了研究。干预后 6 个月,干预组的 SEAMS 中位数得分在统计学上显著高于对照组(中位数 32,IQR 11 vs 中位数 21,IQR 6;U=10,490,PC 结论:在中低收入国家,新型 "多重援助包 "是一项有效的移动医疗干预措施,可提高高血压患者的用药依从性和治疗效果:试验注册:ClinicalTrials.gov NCT04577157; https://clinicaltrials.gov/study/NCT04577157。
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引用次数: 0
Digital Phenotyping of Geriatric Depression Using a Community-Based Digital Mental Health Monitoring Platform for Socially Vulnerable Older Adults and Their Community Caregivers: 6-Week Living Lab Single-Arm Pilot Study. 利用社区数字心理健康监测平台为社会弱势老年人及其社区护理人员进行老年抑郁症的数字表型分析:为期 6 周的生活实验室单臂试点研究。
IF 5.4 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-06-17 DOI: 10.2196/55842
Sunmi Song, YoungBin Seo, SeoYeon Hwang, Hae-Young Kim, Junesun Kim
<p><strong>Background: </strong>Despite the increasing need for digital services to support geriatric mental health, the development and implementation of digital mental health care systems for older adults have been hindered by a lack of studies involving socially vulnerable older adult users and their caregivers in natural living environments.</p><p><strong>Objective: </strong>This study aims to determine whether digital sensing data on heart rate variability, sleep quality, and physical activity can predict same-day or next-day depressive symptoms among socially vulnerable older adults in their everyday living environments. In addition, this study tested the feasibility of a digital mental health monitoring platform designed to inform older adult users and their community caregivers about day-to-day changes in the health status of older adults.</p><p><strong>Methods: </strong>A single-arm, nonrandomized living lab pilot study was conducted with socially vulnerable older adults (n=25), their community caregivers (n=16), and a managerial social worker over a 6-week period during and after the COVID-19 pandemic. Depressive symptoms were assessed daily using the 9-item Patient Health Questionnaire via scripted verbal conversations with a mobile chatbot. Digital biomarkers for depression, including heart rate variability, sleep, and physical activity, were measured using a wearable sensor (Fitbit Sense) that was worn continuously, except during charging times. Daily individualized feedback, using traffic signal signs, on the health status of older adult users regarding stress, sleep, physical activity, and health emergency status was displayed on a mobile app for the users and on a web application for their community caregivers. Multilevel modeling was used to examine whether the digital biomarkers predicted same-day or next-day depressive symptoms. Study staff conducted pre- and postsurveys in person at the homes of older adult users to monitor changes in depressive symptoms, sleep quality, and system usability.</p><p><strong>Results: </strong>Among the 31 older adult participants, 25 provided data for the living lab and 24 provided data for the pre-post test analysis. The multilevel modeling results showed that increases in daily sleep fragmentation (P=.003) and sleep efficiency (P=.001) compared with one's average were associated with an increased risk of daily depressive symptoms in older adults. The pre-post test results indicated improvements in depressive symptoms (P=.048) and sleep quality (P=.02), but not in the system usability (P=.18).</p><p><strong>Conclusions: </strong>The findings suggest that wearable sensors assessing sleep quality may be utilized to predict daily fluctuations in depressive symptoms among socially vulnerable older adults. The results also imply that receiving individualized health feedback and sharing it with community caregivers may help improve the mental health of older adults. However, additional in-person train
背景:尽管对支持老年心理健康的数字服务的需求日益增长,但由于缺乏涉及社会弱势老年人用户及其护理人员在自然生活环境中的研究,阻碍了老年人数字心理健康护理系统的开发和实施:本研究旨在确定有关心率变异性、睡眠质量和体育活动的数字传感数据能否预测社会弱势老年人在日常生活环境中的当天或次日抑郁症状。此外,本研究还测试了数字心理健康监测平台的可行性,该平台旨在向老年人用户及其社区护理人员通报老年人健康状况的日常变化:在 COVID-19 大流行期间和之后的 6 周内,对社会弱势老年人(25 人)、他们的社区照顾者(16 人)和一名管理社工进行了单臂、非随机生活实验室试点研究。每天通过与移动聊天机器人的脚本口头对话,使用 9 项患者健康问卷对抑郁症状进行评估。抑郁症的数字生物标志物,包括心率变异性、睡眠和体力活动,是通过除充电时间外持续佩戴的可穿戴传感器(Fitbit Sense)进行测量的。通过交通信号灯,在移动应用程序上为用户显示老年人在压力、睡眠、体力活动和健康紧急状况方面的健康状况,并在网络应用程序上为其社区护理人员显示每日个性化反馈。研究人员使用多层次模型来检验数字生物标志物是否能预测当天或第二天的抑郁症状。研究人员亲自到老年用户家中进行了事前和事后调查,以监测抑郁症状、睡眠质量和系统可用性的变化:在 31 名老年参与者中,25 人提供了生活实验室数据,24 人提供了前后测试分析数据。多层次建模结果表明,与平均水平相比,每日睡眠碎片(P=.003)和睡眠效率(P=.001)的增加与老年人每日抑郁症状风险的增加有关。前后测试结果表明,抑郁症状(P=.048)和睡眠质量(P=.02)有所改善,但系统可用性(P=.18)没有改善:研究结果表明,评估睡眠质量的可穿戴传感器可用于预测社会弱势老年人抑郁症状的日常波动。研究结果还表明,接收个性化的健康反馈并与社区护理人员分享可能有助于改善老年人的心理健康。不过,要提高可用性,可能还需要额外的面对面培训:ClinicalTrials.gov NCT06270121; https://clinicaltrials.gov/study/NCT06270121.
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引用次数: 0
Remote Inclusion of Vulnerable Users in mHealth Intervention Design: Retrospective Case Analysis. 将弱势用户远程纳入移动医疗干预设计:回顾性案例分析。
IF 5.4 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-06-14 DOI: 10.2196/55548
Ingjerd J Straand, Kimberley A Baxter, Asbjørn Følstad

Background: Mobile health (mHealth) interventions that promote healthy behaviors or mindsets are a promising avenue to reach vulnerable or at-risk groups. In designing such mHealth interventions, authentic representation of intended participants is essential. The COVID-19 pandemic served as a catalyst for innovation in remote user-centered research methods. The capability of such research methods to effectively engage with vulnerable participants requires inquiry into practice to determine the suitability and appropriateness of these methods.

Objective: In this study, we aimed to explore opportunities and considerations that emerged from involving vulnerable user groups remotely when designing mHealth interventions. Implications and recommendations are presented for researchers and practitioners conducting remote user-centered research with vulnerable populations.

Methods: Remote user-centered research practices from 2 projects involving vulnerable populations in Norway and Australia were examined retrospectively using visual mapping and a reflection-on-action approach. The projects engaged low-income and unemployed groups during the COVID-19 pandemic in user-based evaluation and testing of interactive, web-based mHealth interventions.

Results: Opportunities and considerations were identified as (1) reduced barriers to research inclusion; (2) digital literacy transition; (3) contextualized insights: a window into people's lives; (4) seamless enactment of roles; and (5) increased flexibility for researchers and participants.

Conclusions: Our findings support the capability and suitability of remote user methods to engage with users from vulnerable groups. Remote methods facilitate recruitment, ease the burden of research participation, level out power imbalances, and provide a rich and relevant environment for user-centered evaluation of mHealth interventions. There is a potential for a much more agile research practice. Future research should consider the privacy impacts of increased access to participants' environment via webcams and screen share and how technology mediates participants' action in terms of privacy. The development of support procedures and tools for remote testing of mHealth apps with user participants will be crucial to capitalize on efficiency gains and better protect participants' privacy.

背景:促进健康行为或心态的移动保健(mHealth)干预措施是帮助弱势群体或高危人群的一条大有可为的途径。在设计此类移动保健干预措施时,真实反映预期参与者的情况至关重要。COVID-19 大流行推动了以用户为中心的远程研究方法的创新。这些研究方法能否有效地与易受伤害的参与者接触,需要对实践进行探究,以确定这些方法的适用性和适当性:在这项研究中,我们旨在探讨在设计移动医疗干预措施时,让弱势用户群体远程参与的机会和注意事项。为研究人员和从业人员针对弱势人群开展以用户为中心的远程研究提供启示和建议:采用可视化绘图和行动反思法,对挪威和澳大利亚两个涉及弱势群体的项目中以用户为中心的远程研究实践进行了回顾性研究。在 COVID-19 大流行期间,这些项目让低收入和失业群体参与了基于用户的互动式网络移动医疗干预措施的评估和测试:结果:确定的机遇和考虑因素包括:(1) 减少纳入研究的障碍;(2) 数字扫盲过渡;(3) 情境洞察:了解人们生活的窗口;(4) 角色的无缝实施;以及 (5) 增加研究人员和参与者的灵活性:我们的研究结果支持远程用户方法与弱势群体用户互动的能力和适用性。远程方法有利于招募,减轻了参与研究的负担,消除了权力不平衡,并为以用户为中心的移动保健干预评估提供了丰富而相关的环境。研究实践有可能更加灵活。未来的研究应考虑通过网络摄像头和屏幕共享增加对参与者环境的访问对隐私的影响,以及技术如何在隐私方面对参与者的行动进行调解。开发支持程序和工具,以便与用户参与者一起远程测试移动医疗应用程序,这对提高效率和更好地保护参与者的隐私至关重要。
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引用次数: 0
Mobile Health App and Web Platform (eDOL) for Medical Follow-Up of Patients With Chronic Pain: Cohort Study Involving the French eDOL National Cohort After 1 Year. 用于慢性疼痛患者医疗随访的移动健康应用和网络平台 (eDOL):法国 eDOL 国家队列 1 年后的队列研究。
IF 5.4 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-06-12 DOI: 10.2196/54579
Noémie Delage, Nathalie Cantagrel, Sandrine Soriot-Thomas, Marie Frost, Rodrigue Deleens, Patrick Ginies, Alain Eschalier, Alice Corteval, Alicia Laveyssière, Jules Phalip, Célian Bertin, Bruno Pereira, Chouki Chenaf, Bastien Doreau, Nicolas Authier, Nicolas Kerckhove
<p><strong>Background: </strong>Chronic pain affects approximately 30% of the general population, severely degrades quality of life and professional life, and leads to additional health care costs. Moreover, the medical follow-up of patients with chronic pain remains complex and provides only fragmentary data on painful daily experiences. This situation makes the management of patients with chronic pain less than optimal and may partly explain the lack of effectiveness of current therapies. Real-life monitoring of subjective and objective markers of chronic pain using mobile health (mHealth) programs could better characterize patients, chronic pain, pain medications, and daily impact to help medical management.</p><p><strong>Objective: </strong>This cohort study aimed to assess the ability of our mHealth tool (eDOL) to collect extensive real-life medical data from chronic pain patients after 1 year of use. The data collected in this way would provide new epidemiological and pathophysiological data on chronic pain.</p><p><strong>Methods: </strong>A French national cohort of patients with chronic pain treated at 18 pain clinics has been established and followed up using mHealth tools. This cohort makes it possible to collect the determinants and repercussions of chronic pain and their evolutions in a real-life context, taking into account all environmental events likely to influence chronic pain. The patients were asked to complete several questionnaires, body schemes, and weekly meters, and were able to interact with a chatbot and use educational modules on chronic pain. Physicians could monitor their patients' progress in real time via an online platform.</p><p><strong>Results: </strong>The cohort study included 1427 patients and analyzed 1178 patients. The eDOL tool was able to collect various sociodemographic data; specific data for characterizing pain disorders, including body scheme; data on comorbidities related to chronic pain and its psychological and overall impact on patients' quality of life; data on drug and nondrug therapeutics and their benefit-to-risk ratio; and medical or treatment history. Among the patients completing weekly meters, 49.4% (497/1007) continued to complete them after 3 months of follow-up, and the proportion stabilized at 39.3% (108/275) after 12 months of follow-up. Overall, despite a fairly high attrition rate over the follow-up period, the eDOL tool collected extensive data. This amount of data will increase over time and provide a significant volume of health data of interest for future research involving the epidemiology, care pathways, trajectories, medical management, sociodemographic characteristics, and other aspects of patients with chronic pain.</p><p><strong>Conclusions: </strong>This work demonstrates that the mHealth tool eDOL is able to generate a considerable volume of data concerning the determinants and repercussions of chronic pain and their evolutions in a real-life context. The eDOL tool can in
背景:慢性疼痛影响着约 30% 的普通人群,严重降低生活质量和职业生活,并导致额外的医疗费用。此外,对慢性疼痛患者的医学随访仍然很复杂,只能提供有关日常疼痛经历的零碎数据。这种情况使得对慢性疼痛患者的管理不尽如人意,这也是当前疗法缺乏有效性的部分原因。利用移动医疗(mHealth)程序对慢性疼痛的主观和客观指标进行实时监测,可以更好地描述患者、慢性疼痛、止痛药物和日常影响,从而帮助医疗管理:这项队列研究旨在评估我们的移动医疗工具(eDOL)在使用一年后收集慢性疼痛患者大量真实医疗数据的能力。通过这种方式收集的数据将为慢性疼痛提供新的流行病学和病理生理学数据:方法:建立了一个法国全国慢性疼痛患者队列,这些患者在 18 家疼痛诊所接受治疗,并使用移动医疗工具进行随访。通过该队列,可以收集慢性疼痛的决定因素和反作用力及其在现实生活中的演变,同时考虑到可能影响慢性疼痛的所有环境事件。患者被要求填写几份问卷、身体计划和每周测量表,并能与聊天机器人互动,使用有关慢性疼痛的教育模块。医生可通过在线平台实时监控患者的病情进展:这项队列研究包括 1427 名患者,分析了 1178 名患者。eDOL 工具能够收集各种社会人口学数据;描述疼痛疾病特点的具体数据,包括身体方案;与慢性疼痛相关的合并症数据及其对患者生活质量的心理和整体影响;药物和非药物疗法及其效益风险比数据;以及医疗或治疗史。在完成每周测量的患者中,49.4%(497/1007)在随访 3 个月后继续完成测量,这一比例在随访 12 个月后稳定在 39.3%(108/275)。总体而言,尽管随访期间的流失率相当高,但 eDOL 工具收集了大量数据。随着时间的推移,这些数据量将会增加,并为未来涉及慢性疼痛患者的流行病学、护理路径、轨迹、医疗管理、社会人口特征和其他方面的研究提供大量有价值的健康数据:这项工作表明,移动医疗工具 eDOL 能够生成大量数据,这些数据涉及慢性疼痛的决定因素和影响,以及它们在现实生活中的演变。eDOL 工具可纳入大量参数,确保为未来研究和疼痛管理详细描述慢性疼痛患者的特征:试验注册:ClinicalTrials.gov NCT04880096;https://clinicaltrials.gov/ct2/show/NCT04880096。
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引用次数: 0
Effectiveness of Mobile-Based Progressive and Fixed Physical Activity on Depression, Stress, Anxiety, and Quality of Life Outcomes Among Adults in South Korea: Randomized Controlled Trial. 基于移动设备的渐进式体育活动和固定式体育活动对韩国成年人抑郁、压力、焦虑和生活质量结果的影响:随机对照试验
IF 5.4 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-06-12 DOI: 10.2196/55578
Ye Hoon Lee, Hyungsook Kim, Juhee Hwang, Sihyeon Noh

Background: Depression acts as a significant obstacle to the overall well-being of individuals. Given the significant consequences, timely recognition and proactive steps to manage symptoms of depression become essential. Such actions not only reduce personal distress but also play a crucial role in reducing its far-reaching impact on society as a whole.

Objective: In response to this concern, the objective of this study was to explore the use of mobile-based interventions as a possible remedy. More specifically, this study aimed to investigate the effectiveness of 2 types of physical activity (PA), progressive and fixed, within a mobile-based app on depression, perceived stress, anxiety, physical health, and psychological health, aiming to contribute to the optimization of mental health benefits.

Methods: Participants (N=60; mean age 25.29, SD 6.10 years) were recruited using a combination of web-based and offline methods, and the study lasted for 8 weeks. The baseline and posttest questionnaires were administered to all participants. The participants were randomly assigned to 1 of the 3 groups: progressive group (n=20; performing mobile-based progressive PA), fixed group (n=20; performing mobile-based fixed intensity PA), and control group C (n=20). Data analysis involved comparing scores between the experimental and control groups using a one-way ANOVA, paired sample t tests (2-tailed), and repeated measures ANOVA with a 3 (group)×2 (time) design.

Results: The findings revealed significant improvements in mental health indicators among participants engaged in both fixed and progressive PA groups compared with the control group. However, the fixed PA group demonstrated more significant reductions in symptoms. Specifically, the progressive PA group showed significant reductions in depression (F1,36=6.941; P=.01; ηp2=0.16) and perceived stress (F1,36=5.47; P=.03; ηp2=0.13), while the fixed PA group exhibited significant reductions in depression (F1,37=5.36; P=.03; ηp2=0.12), perceived stress (F1,37=7.81; P=.008; ηp2=0.17), and general anxiety disorder (F1,37=5.45; P=.03; ηp2=0.13) compared with the control group.

Conclusions: This study underscores the potential of mobile-based PA in improving mental health outcomes. The findings offer significant insights for mental health professionals and researchers aiming to optimize mental well-being through innovative mobile therapies.

Trial registration: Clinical Research Information Service KCT0009100; https://tinyurl.com/mr33fmur.

背景:抑郁症是个人整体健康的重大障碍。鉴于其严重后果,及时发现并采取积极措施来控制抑郁症状就变得至关重要。这些措施不仅能减轻个人的痛苦,还能在减少抑郁症对整个社会的深远影响方面发挥至关重要的作用:针对这一问题,本研究旨在探索使用基于移动技术的干预措施作为一种可能的补救措施。更具体地说,本研究旨在调查基于移动应用程序的渐进式和固定式两种体育活动(PA)对抑郁症、感知压力、焦虑、身体健康和心理健康的影响,从而为优化心理健康效益做出贡献:通过网络和线下相结合的方式招募参与者(60 人;平均年龄 25.29 岁,平均年龄(SD)6.10 岁),研究持续 8 周。对所有参与者进行了基线和后测问卷调查。参与者被随机分配到 3 组中的一组:渐进组(20 人;进行基于移动设备的渐进式运动负荷训练)、固定组(20 人;进行基于移动设备的固定强度运动负荷训练)和对照组 C(20 人)。数据分析包括使用单因素方差分析、配对样本 t 检验(双尾)和 3(组)×2(时间)设计的重复测量方差分析比较实验组和对照组的得分:结果:研究结果表明,与对照组相比,参加固定和渐进式活动量组的参与者的心理健康指标均有明显改善。然而,固定 PA 组的症状减少更为明显。具体来说,渐进式 PA 组的抑郁(F1,36=6.941;P=.01;ηp2=0.16)和感知压力(F1,36=5.47;P=.03;ηp2=0.13)明显减少,而固定式 PA 组的抑郁(F1,37=5.36;P=.03;ηp2=0.12)、感知压力(F1,37=7.81;P=.008;ηp2=0.17)和一般焦虑症(F1,37=5.45;P=.03;ηp2=0.13)与对照组相比均有明显降低:本研究强调了基于移动设备的 PA 在改善心理健康结果方面的潜力。研究结果为旨在通过创新移动疗法优化心理健康的心理健康专业人员和研究人员提供了重要启示:临床研究信息服务 KCT0009100; https://tinyurl.com/mr33fmur。
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引用次数: 0
Engagement in mHealth-Prompted Self-Measured Blood Pressure Monitoring Among Participants Recruited From a Safety-Net Emergency Department: Secondary Analysis of the Reach Out Trial. 从安全网急诊科招募的参与者参与移动医疗提示的自我测量血压监测:Reach Out试验的二次分析。
IF 5.4 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-06-12 DOI: 10.2196/54946
Lesli E Skolarus, Chun Chieh Lin, Sonali Mishra, William Meurer, Mackenzie Dinh, Candace Whitfield, Ran Bi, Devin Brown, Rockefeller Oteng, Lorraine R Buis, Kelley Kidwell
<p><strong>Background: </strong>Hypertension, a key modifiable risk factor for cardiovascular disease, is more prevalent among Black and low-income individuals. To address this health disparity, leveraging safety-net emergency departments for scalable mobile health (mHealth) interventions, specifically using text messaging for self-measured blood pressure (SMBP) monitoring, presents a promising strategy. This study investigates patterns of engagement, associated factors, and the impact of engagement on lowering blood pressure (BP) in an underserved population.</p><p><strong>Objective: </strong>We aimed to identify patterns of engagement with prompted SMBP monitoring with feedback, factors associated with engagement, and the association of engagement with lowered BP.</p><p><strong>Methods: </strong>This is a secondary analysis of data from Reach Out, an mHealth, factorial trial among 488 hypertensive patients recruited from a safety-net emergency department in Flint, Michigan. Reach Out participants were randomized to weekly or daily text message prompts to measure their BP and text in their responses. Engagement was defined as a BP response to the prompt. The k-means clustering algorithm and visualization were used to determine the pattern of SMBP engagement by SMBP prompt frequency-weekly or daily. BP was remotely measured at 12 months. For each prompt frequency group, logistic regression models were used to assess the univariate association of demographics, access to care, and comorbidities with high engagement. We then used linear mixed-effects models to explore the association between engagement and systolic BP at 12 months, estimated using average marginal effects.</p><p><strong>Results: </strong>For both SMBP prompt groups, the optimal number of engagement clusters was 2, which we defined as high and low engagement. Of the 241 weekly participants, 189 (78.4%) were low (response rate: mean 20%, SD 23.4) engagers, and 52 (21.6%) were high (response rate: mean 86%, SD 14.7) engagers. Of the 247 daily participants, 221 (89.5%) were low engagers (response rate: mean 9%, SD 12.2), and 26 (10.5%) were high (response rate: mean 67%, SD 8.7) engagers. Among weekly participants, those who were older (>65 years of age), attended some college (vs no college), married or lived with someone, had Medicare (vs Medicaid), were under the care of a primary care doctor, and took antihypertensive medication in the last 6 months had higher odds of high engagement. Participants who lacked transportation to appointments had lower odds of high engagement. In both prompt frequency groups, participants who were high engagers had a greater decline in BP compared to low engagers.</p><p><strong>Conclusions: </strong>Participants randomized to weekly SMBP monitoring prompts responded more frequently overall and were more likely to be classed as high engagers compared to participants who received daily prompts. High engagement was associated with a larger decrease in BP.
背景:高血压是心血管疾病的主要可改变风险因素,在黑人和低收入人群中更为普遍。为解决这一健康差异问题,利用安全网急诊科进行可扩展的移动医疗(mHealth)干预,特别是使用短信进行自我血压(SMBP)监测,是一项很有前景的策略。本研究调查了服务不足人群的参与模式、相关因素以及参与对降低血压(BP)的影响:我们旨在确定参与有反馈提示的 SMBP 监测的模式、与参与相关的因素以及参与与血压降低的关系:这是对从密歇根州弗林特市安全网急诊科招募的 488 名高血压患者进行的移动医疗因子试验 Reach Out 数据的二次分析。Reach Out 的参与者被随机分配到每周或每天的短信提示中,测量他们的血压并发送短信回复。参与度定义为对提示的血压回复。采用 k-means 聚类算法和可视化方法,根据 SMBP 提示频率(每周或每天)确定 SMBP 参与模式。在 12 个月时对血压进行远程测量。对于每个提示频率组,我们使用逻辑回归模型来评估人口统计学、获得护理的机会和合并症与高参与度的单变量关联。然后,我们使用线性混合效应模型探讨参与度与 12 个月时收缩压之间的关系,并使用平均边际效应进行估算:对于两个 SMBP 提示组,最佳参与度群组数为 2,我们将其定义为高参与度和低参与度。在 241 名每周参与者中,189 人(78.4%)为低参与度者(响应率:平均为 20%,标准差为 23.4),52 人(21.6%)为高参与度者(响应率:平均为 86%,标准差为 14.7)。在 247 名每日参与者中,221 人(89.5%)为低参与度(回复率:平均 9%,中位数 12.2),26 人(10.5%)为高参与度(回复率:平均 67%,中位数 8.7)。在每周的参与者中,年龄较大(大于 65 岁)、上过一些大学(与未上过大学相比)、已婚或与他人同住、有医疗保险(与医疗补助相比)、接受初级保健医生的治疗以及在过去 6 个月中服用过抗高血压药物的人参与度高的几率更高。没有交通工具赴约的参与者参与度较低。在两个提示频率组中,参与度高的参与者与参与度低的参与者相比,血压下降幅度更大:结论:与接受每日提示的参与者相比,随机接受每周 SMBP 监测提示的参与者总体上更频繁地做出反应,更有可能被归类为高参与度者。参与度高与血压下降幅度大有关。需要为获得医疗服务机会较少的参与者制定新的鼓励参与策略。
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引用次数: 0
Doctors' Personal Preference and Adoption of Mobile Apps to Communicate with Patients in China: Qualitative Study. 中国医生个人偏好及采用移动应用程序与患者沟通的情况:定性研究。
IF 5.4 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-06-10 DOI: 10.2196/49040
Dongjin Chen, Wenchao Han, Yili Yang, Jay Pan

Background: Different kinds of mobile apps are used to promote communications between patients and doctors. Studies have investigated patients' mobile app adoption behavior; however, they offer limited insights into doctors' personal preferences among a variety of choices of mobile apps.

Objective: This study aimed to investigate the nuanced adoption behaviors among doctors in China, which has a robust adoption of mobile apps in health care, and to explore the constraints influencing their selection of specific mobile apps. This paper addressed 3 research questions: (1) Which doctors opt to adopt mobile apps to communicate with patients? (2) What types of mobile apps do they choose? (3) To what degree do they exercise personal choice in adopting specific mobile apps?

Methods: We used thematic content analysis of qualitative data gathered from semistructured interviews with 11 doctors in Hangzhou, which has been recognized for its advanced adoption of mobile technology in social services, including health care services. The selection of participants was purposive, encompassing diverse departments and hospitals.

Results: In total, 5 themes emerged from the data analysis. First, the interviewees had a variety of options for communicating with patients via mobile apps, with the predominant ones being social networking apps (eg, WeChat) and medical platforms (eg, Haodf). Second, all interviewees used WeChat to facilitate communication with patients, although their willingness to share personal accounts varied (they are more likely to share with trusty intermediaries). Third, fewer than half of the doctors adopted medical platforms, and they were all from tertiary hospitals. Fourth, the preferences for in-person, WeChat, or medical platform communication reflected the interviewees' perceptions of different patient cohorts. Lastly, the selection of a particular kind of mobile app was significantly influenced by the doctors' affiliation with hospitals, driven by their professional obligations to fulfill multiple tasks assigned by the hospitals or the necessity of maintaining social connections with their colleagues.

Conclusions: Our findings contribute to a nuanced understanding of doctors' adoption behavior regarding specific types of mobile apps for patient communication, instead of addressing such adoption behavior of a wide range of mobile apps as equal. Their choices of a particular kind of app were positioned within a social context where health care policies (eg, limited funding for public hospitals, dominance of public health care institutions, and absence of robust referral systems) and traditional culture (eg, trust based on social connections) largely shape their behavioral patterns.

背景:不同类型的移动应用程序被用于促进患者与医生之间的沟通。已有研究调查了患者采用移动应用程序的行为;然而,这些研究对医生在各种移动应用程序选择中的个人偏好提供的洞察有限:本研究旨在调查中国医生在医疗保健领域采用移动应用程序的细微差别,并探讨影响他们选择特定移动应用程序的制约因素。本文探讨了三个研究问题:(1) 哪些医生选择采用移动应用程序与患者沟通?(2) 他们选择哪些类型的移动应用程序?(3) 在采用特定移动应用程序时,他们在多大程度上行使了个人选择权?杭州因其在社会服务(包括医疗服务)中采用移动技术的先进水平而备受赞誉,我们采用专题内容分析法对杭州的 11 名医生进行了半结构式访谈。参与者的选择具有目的性,包括不同的科室和医院:数据分析共产生了 5 个主题。首先,受访者有多种选择通过移动应用程序与患者沟通,其中最主要的是社交网络应用程序(如微信)和医疗平台(如 Haodf)。其次,所有受访者都使用微信来促进与患者的沟通,尽管他们分享个人账户的意愿各不相同(他们更愿意与信任的中间人分享)。第三,采用医疗平台的医生不到一半,而且他们都来自三级医院。第四,受访者对面对面交流、微信交流或医疗平台交流的偏好反映了他们对不同患者群体的看法。最后,医生选择特定类型的移动应用程序在很大程度上受到他们与医院隶属关系的影响,这是因为他们有职业义务完成医院分配的多项任务,或有必要与同事保持社交联系:我们的研究结果有助于深入了解医生采用特定类型移动应用程序与患者交流的行为,而不是把他们采用各种移动应用程序的行为等同看待。他们对特定类型应用程序的选择是在医疗政策(如公立医院资金有限、公立医疗机构占主导地位、缺乏健全的转诊系统)和传统文化(如基于社会关系的信任)在很大程度上影响其行为模式的社会背景下做出的。
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引用次数: 0
Use of Mobile Technologies to Streamline Pretriage Patient Flow in the Emergency Department: Observational Usability Study. 使用移动技术简化急诊科预诊患者流程:可用性观察研究。
IF 5.4 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-06-07 DOI: 10.2196/54642
Panzhang Wang, Lei Yu, Tao Li, Liang Zhou, Xin Ma
<p><strong>Background: </strong>In emergency departments (EDs), triage nurses are under tremendous daily pressure to rapidly assess the acuity level of patients and log the collected information into computers. With self-service technologies, patients could complete data entry on their own, allowing nurses to focus on higher-order tasks. Kiosks are a popular working example of such self-service technologies; however, placing a sufficient number of unwieldy and fixed machines demands a spatial change in the greeting area and affects pretriage flow. Mobile technologies could offer a solution to these issues.</p><p><strong>Objective: </strong>The aim of this study was to investigate the use of mobile technologies to improve pretriage flow in EDs.</p><p><strong>Methods: </strong>The proposed stack of mobile technologies includes patient-carried smartphones and QR technology. The web address of the self-registration app is encoded into a QR code, which was posted directly outside the walk-in entrance to be seen by every ambulatory arrival. Registration is initiated immediately after patients or their proxies scan the code using their smartphones. Patients could complete data entry at any site on the way to the triage area. Upon completion, the result is saved locally on smartphones. At the triage area, the result is automatically decoded by a portable code reader and then loaded into the triage computer. This system was implemented in three busy metropolitan EDs in Shanghai, China. Both kiosks and smartphones were evaluated randomly while being used to direct pretriage patient flow. Data were collected during a 20-day period in each center. Timeliness and usability of medical students simulating ED arrivals were assessed with the After-Scenario Questionnaire. Usability was assessed by triage nurses with the Net Promoter Score (NPS). Observations made during system implementation were subject to qualitative thematic analysis.</p><p><strong>Results: </strong>Overall, 5928 of 8575 patients performed self-registration on kiosks, and 7330 of 8532 patients checked in on their smartphones. Referring effort was significantly reduced (43.7% vs 8.8%; P<.001) and mean pretriage waiting times were significantly reduced (4.4, SD 1.7 vs 2.9, SD 1.0 minutes; P<.001) with the use of smartphones compared to kiosks. There was a significant difference in mean usability scores for "ease of task completion" (4.4, SD 1.5 vs 6.7, SD 0.7; P<.001), "satisfaction with completion time" (4.5, SD 1.4 vs 6.8, SD 0.6; P<.001), and "satisfaction with support" (4.9, SD 1.9 vs 6.6, SD 1.2; P<.001). Triage nurses provided a higher NPS after implementation of mobile self-registration compared to the use of kiosks (13.3% vs 93.3%; P<.001). A modified queueing model was identified and qualitative findings were grouped by sequential steps.</p><p><strong>Conclusions: </strong>This study suggests patient-carried smartphones as a useful tool for ED self-registration. With increased usability
背景:在急诊科(ED),分诊护士每天都面临着巨大的压力,需要快速评估病人的严重程度,并将收集到的信息录入电脑。有了自助服务技术,病人可以自行完成数据录入,这样护士就可以专注于更高阶的任务。自助服务终端是此类自助服务技术的常用工作范例;然而,放置足够数量的笨重而固定的机器需要改变问候区的空间,并影响分诊流程。移动技术可以解决这些问题:本研究旨在探讨如何利用移动技术改善急诊室的预分诊流程:方法:所建议的移动技术堆栈包括患者携带的智能手机和 QR 技术。自助登记应用程序的网址被编码成一个二维码,直接张贴在门诊入口处,让每一位前来就诊的患者都能看到。患者或其代理人使用智能手机扫描二维码后,注册立即启动。患者可以在前往分诊区的途中在任何地点完成数据输入。完成后,结果会保存在智能手机本地。在分诊区,结果由便携式读码器自动解码,然后载入分诊电脑。该系统在中国上海三家繁忙的大都市急诊室实施。在使用信息亭和智能手机引导预分诊病人流时,对两者进行了随机评估。数据在每个中心收集了 20 天。医学生模拟急诊室到达的及时性和可用性通过事后情景问卷进行了评估。分诊护士使用净推荐值 (NPS) 对可用性进行评估。对系统实施过程中的观察结果进行了定性专题分析:总体而言,8575 名患者中有 5928 人在自助服务机上进行了自助登记,8532 名患者中有 7330 人在智能手机上办理了登记手续。转诊工作量明显减少(43.7% 对 8.8%;个人电脑):这项研究表明,患者携带的智能手机是急诊室自助登记的有用工具。随着可用性的提高和排队模式的改进,该系统有望最大限度地减少急诊室患者的排队等候时间。
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引用次数: 0
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