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Identifying Time-Variant Predictors of Interest in Completing Brief Digital Mental Health Interventions Among Adult Survivors of Cancer: Ecological Momentary Assessment Study. 确定成年癌症幸存者完成简短数字心理健康干预的时变预测因素:生态瞬时评估研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-18 DOI: 10.2196/69244
Katharine E Daniel, James W Kinchen, Angela Chang, Patrick H Finan, Philip I Chow
<p><strong>Background: </strong>Digital microinterventions have strong potential to improve the lives of adults diagnosed with cancer. However, little is known about which types of digital microinterventions are most desired and how contextual factors may influence those preferences. This potentially limits guidance for personalized and timely digital microintervention delivery.</p><p><strong>Objective: </strong>This study aims to identify time-varying and person-level predictors of relative digital microintervention interest among adult survivors of cancer.</p><p><strong>Methods: </strong>We enrolled US adults within 5 years of a cancer diagnosis in a 5-week observational study using ecological momentary assessment. Participants (N=407) were asked 3 times a day for 5 weeks which of 9 brief, mobile-delivered interventions, if any, they would have been interested in completing within the past hour. Intervention options were (1) reducing worry, (2) reducing negative thoughts, (3) problem solving, (4) increasing positive emotions, (5) connecting with values, (6) guided relaxation, (7) getting support from others, (8) setting goals, and (9) something else. Multinomial models were used to identify demographic (ie, age), cancer-related (ie, treatment status), and psychological (ie, depression symptom severity, anxiety symptom severity, history of major depressive diagnosis, history of anxiety disorder diagnosis, and psychotherapy status) predictors of individual differences in modal intervention preference. Multilevel logistic and multilevel multinomial models were used to identify momentary negative affect, positive affect, and pain predictors of relative intervention interest.</p><p><strong>Results: </strong>Participants indicated interest in completing a digital microintervention in 87% (20,429/23,472) of completed surveys. The most frequently selected intervention option was guided relaxation (8611/20,429, 42%). Neither cancer treatment status (χ<sup>2</sup><sub>9</sub>=6.5; P=.69) nor psychotherapy status (χ<sup>2</sup><sub>9</sub>=14.0; P=.12) differentiated between modal intervention preferences. Participants with greater anxiety (χ<sup>2</sup><sub>9</sub>=35.1; P<.001) and depression symptom severity (χ<sup>2</sup><sub>9</sub>=23.0; P=.006) were less likely to modally endorse guided relaxation compared to other intervention options like increasing positive emotions, reducing negative thoughts, and getting support from others. Higher momentary negative affect and pain and lower momentary positive affect each predicted a greater likelihood to endorse interest in completing an intervention (vs not completing an intervention; P<.05) and to endorse interest in completing multiple interventions (vs only one; P<.001). Finally, higher momentary negative affect generally predicted greater interest in completing an intervention other than guided relaxation, whereas higher momentary pain generally predicted greater relative interest in guided relaxation.<
背景:数字微干预在改善成年癌症患者的生活方面具有强大的潜力。然而,对于哪种类型的数字微干预是最需要的,以及环境因素如何影响这些偏好,人们知之甚少。这可能会限制对个性化和及时的数字微干预提供的指导。目的:本研究旨在确定成年癌症幸存者相对数字微干预兴趣的时变和个人水平预测因素。方法:我们在一项为期5周的观察性研究中招募了被诊断为癌症的5年内的美国成年人,使用生态瞬时评估。参与者(N=407)在5周内每天被询问3次,如果有的话,他们有兴趣在过去一小时内完成9个简短的、移动交付的干预措施中的哪一个。干预选项有:(1)减少忧虑,(2)减少消极想法,(3)解决问题,(4)增加积极情绪,(5)与价值观联系,(6)引导放松,(7)获得他人支持,(8)设定目标,以及(9)其他事情。使用多项模型来确定人口统计学(即年龄)、癌症相关(即治疗状况)和心理(即抑郁症状严重程度、焦虑症状严重程度、重度抑郁诊断史、焦虑障碍诊断史和心理治疗状况)预测因素在模态干预偏好方面的个体差异。采用多水平逻辑模型和多水平多项模型来识别瞬时负面影响、积极影响和相对干预兴趣的疼痛预测因子。结果:87%(20,429/23,472)的参与者表示有兴趣完成数字微干预。最常选择的干预方案是引导放松(8611/ 20429,42%)。癌症治疗状态(χ29=6.5; P= 0.69)和心理治疗状态(χ29=14.0; P= 0.12)在模式干预偏好之间均无差异。焦虑程度较高的参与者(χ29=35.1; P29=23.0; P= 0.006)与其他干预方案(如增加积极情绪、减少消极想法和获得他人支持)相比,在模式上支持引导放松的可能性较小。较高的瞬时负面影响和疼痛以及较低的瞬时积极影响均预示着更大的可能性支持完成干预的兴趣(与不完成干预相比)。结论:成年癌症幸存者在人与人之间和人与人之间的数字微干预偏好不同。当癌症幸存者处于更大的情绪困扰时,单独的引导式放松不太有吸引力,但在应对疼痛增加的情况时可能更有吸引力。
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引用次数: 0
Digital Physiotherapeutic Ankle-Specific Training System for Patients With Chronic Ankle Instability Following Modified Brostrom Surgery: Noninferiority Randomized Controlled Trial at a Tertiary Grade A Trauma Center in China. 改良Brostrom手术后慢性踝关节不稳定患者的数字物理治疗踝关节特异性训练系统:中国三级创伤中心的非低质量随机对照试验。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-18 DOI: 10.2196/78307
Xiang Geng, Yilin Jin, Xu Wang, Xin Zhang, Yiming Lyu, Shengdi Lu, Xin Ma
<p><strong>Background: </strong>Functional rehabilitation is commonly used for patients with chronic ankle instability (CAI). Digital training (DT) systems have become increasingly popular in postoperative rehabilitation; however, their effectiveness for CAI patients after modified Brostrom surgery (MBS) is uncertain. Furthermore, specialized physiotherapy resources for CAI are limited in some regions, highlighting the need for effective digital home-based rehabilitation alternatives.</p><p><strong>Objective: </strong>This trial aimed to evaluate whether individually tailored physiotherapeutic ankle-specific training (PAST) delivered via a DT system is noninferior to conventional face-to-face physiotherapy in clinical outcomes and to compare their cost-effectiveness in CAI patients following MBS in China.</p><p><strong>Methods: </strong>We conducted a 2-arm, single-blinded (assessor), noninferiority randomized controlled trial at a tertiary hospital in Shanghai, China, from January 2022 to January 2024. A total of 84 postsurgery CAI patients were randomly assigned to a DT group (n=42), which received a 12-week individualized PAST program via a digital system, or a physiotherapy group (n=42), which received standard face-to-face physiotherapy for 12 weeks. Assessments were performed at baseline, 12 weeks, and 24 weeks postoperatively. The primary outcomes were 2 subscales of the Foot and Ankle Ability Measure, with a noninferiority margin of 8 points for Foot and Ankle Ability Measure-Activities of Daily Living (FAAM-ADL) and 9 points for Foot and Ankle Ability Measure-Sports (FAAM-S). Secondary outcomes included balance tests (time-in-balance, foot-lift, and star excursion balance), functional tests (ankle dorsiflexion range of motion, side-hop, and figure-8 hop), and quality of life (FAAM questionnaire). We also collected intervention costs to evaluate cost-effectiveness. Statistical analyses included between-group comparisons of outcomes and nonparametric bootstrapping to calculate incremental cost-effectiveness ratios.</p><p><strong>Results: </strong>Baseline characteristics were similar between groups (except for a difference in foot-lift test performance). By the 24-week follow-up, improvements in the primary outcomes were comparable between the DT and physiotherapy groups, with adjusted between-group differences of 0.36 (95% CI -1.01 to 1.72) for FAAM-ADL and 1.67 (95% CI -0.61 to 3.96) for FAAM-S. These differences fell within the predefined noninferiority margins, demonstrating noninferiority of the digital program. No significant between-group differences were observed in secondary outcomes (all P>.05). The average cost per patient was lower in the DT group (CNY 53,551; an exchange rate of US $1=CNY 7 was applied) than in the physiotherapy group (CNY 59,372), yielding an incremental cost of CNY -14,451 in favor of the digital intervention. The bootstrapped incremental cost-effectiveness ratios were CNY -16,396 for FAAM-ADL and CNY -114,1
背景:功能康复是治疗慢性踝关节不稳定(CAI)的常用方法。数字训练(DT)系统在术后康复中越来越受欢迎;然而,它们对改良Brostrom手术(MBS)后CAI患者的有效性尚不确定。此外,在一些地区,专门用于CAI的物理治疗资源有限,这突出了对有效的数字家庭康复替代方案的需求。目的:本试验旨在评估通过DT系统提供的个性化物理治疗踝关节特异性训练(PAST)在临床结果上是否优于传统面对面物理治疗,并比较它们在中国MBS后CAI患者中的成本效益。方法:我们于2022年1月至2024年1月在中国上海的一家三级医院进行了一项双组、单盲(评估者)、非劣效性随机对照试验。84例术后CAI患者被随机分为DT组(n=42)和物理治疗组(n=42), DT组通过数字系统接受为期12周的个性化PAST计划,物理治疗组(n=42)接受为期12周的标准面对面物理治疗。在基线、术后12周和术后24周进行评估。主要结果为足踝能力测量的2个分量表,足踝能力测量-日常生活活动(FAAM-ADL)非效度为8分,足踝能力测量-运动(FAAM-S)非效度为9分。次要结果包括平衡测试(平衡时间、抬脚和星移平衡)、功能测试(踝关节背屈运动范围、侧跳和8字形跳)和生活质量(FAAM问卷)。我们还收集了干预成本来评估成本效益。统计分析包括组间结果比较和非参数引导来计算增量成本-效果比。结果:两组之间的基线特征相似(除了脚举测试表现的差异)。在24周的随访中,DT组和物理治疗组的主要预后改善具有可比性,FAAM-ADL组调整后的组间差异为0.36 (95% CI -1.01至1.72),FAAM-S组调整后的组间差异为1.67 (95% CI -0.61至3.96)。这些差异落在预定义的非劣效性范围内,表明数字程序的非劣效性。次要结局组间无显著差异(均P < 0.05)。DT组每位患者的平均成本(53,551元人民币;汇率为1美元= 7元人民币)低于物理治疗组(59,372元人民币),因此数字干预的增量成本为-14,451元人民币。FAAM-ADL的自启动增量成本-效果比为-16,396元,FAAM-S的自启动增量成本-效果比为-114,131元,说明DT更具成本效益。结论:通过DT系统提供的个性化定制PAST在临床上优于传统的面对面物理治疗,并且更具成本效益,支持其作为MBS后CAI患者可行的康复选择。
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引用次数: 0
Improvement in Quality of Life After Early Interactive Human Coaching via a Mobile App in Postgastrectomy Patients With Gastric Cancer: Prospective Randomized Controlled Trial. 胃切除术后胃癌患者通过移动应用程序进行早期互动人类指导后生活质量的改善:前瞻性随机对照试验
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-18 DOI: 10.2196/75445
Bang Wool Eom, Mira Han, Hong Man Yoon, Young-Woo Kim, So Young Kim, Jin Myoung Oh, Gyung Ah Wie, Keun Won Ryu
<p><strong>Background: </strong>Patients undergoing gastrectomy usually experience postgastrectomy syndrome and face difficulties adapting to a regular diet. Human health coaching via a mobile app has recently been applied to patients with chronic metabolic diseases, with significant improvements being observed in clinical outcomes.</p><p><strong>Objective: </strong>This study aimed to compare the quality of life and nutritional outcomes of human health coaching via a mobile app with those of conventional face-to-face counseling in postgastrectomy patients with gastric cancer.</p><p><strong>Methods: </strong>This was a prospective randomized controlled trial, and patients were enrolled between May 2020 and August 2022. The mobile coaching group received health coaching that provides personalized advice based on self-recorded health data via a mobile app from assigned coaches for 3 months after discharge, and the conventional counseling group underwent dietary consultations with a clinical dietitian 1 and 3 months postoperatively. The primary end point for sample size calculation was the eating restriction score on the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire gastric cancer module 1 month postoperatively. Secondary end points included changes in other subscales of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 and gastric cancer module, as well as nutritional outcomes assessed preoperatively and 1, 3, 6, and 12 months postoperatively.</p><p><strong>Results: </strong>Data from 88.9% (160/180) of enrolled patients were analyzed after excluding dropouts. In the mobile coaching group (n=76), 66% (n=50) of patients who used the mobile app for ≥8 weeks were classified as active users. No significant difference in eating restriction 1 month postoperatively was found between the mobile coaching and conventional counseling groups. However, the mobile coaching group reported less dyspnea during the entire period (P=.01), less eating restriction at 6 months (P=.045), and less negative body image 3 months postoperatively (P=.04) than the conventional counseling group (n=84). Exploratory subgroup analyses based on age, sex, and operation type indicated that younger patients (<60 years), female patients, and those who underwent distal gastrectomy had better quality of life from mobile coaching. In the mobile coaching group, exploratory subgroup analyses based on mobile activity showed that active users had a better global health status than inactive users (P=.005). However, no significant differences in body composition or nutritional parameters were observed between the mobile coaching and conventional counseling groups or between active and inactive users in the mobile coaching group.</p><p><strong>Conclusions: </strong>Although this trial did not show a significant difference in eating restriction 1 month postoperatively, human coaching via a mobile app was
背景:接受胃切除术的患者通常会经历胃切除术后综合征,并且难以适应正常的饮食。通过移动应用程序的人类健康指导最近被应用于慢性代谢性疾病患者,在临床结果中观察到显着改善。目的:本研究旨在比较通过移动应用程序进行人类健康指导与传统面对面咨询对胃切除术后胃癌患者的生活质量和营养结局的影响。方法:这是一项前瞻性随机对照试验,患者于2020年5月至2022年8月入组。移动辅导组在出院后3个月接受由指定教练通过移动应用程序根据自己记录的健康数据提供个性化建议的健康辅导,常规辅导组在术后1个月和3个月接受临床营养师的饮食咨询。计算样本量的主要终点是术后1个月欧洲癌症研究和治疗组织生活质量问卷胃癌模块的饮食限制评分。次要终点包括欧洲癌症研究和治疗组织生活质量问卷核心30和胃癌模块的其他亚量表的变化,以及术前和术后1、3、6和12个月评估的营养结果。结果:88.9%(160/180)的入组患者在排除退出后进行了数据分析。在移动教练组(n=76)中,66% (n=50)使用移动app≥8周的患者被归类为活跃用户。术后1个月,移动辅导组与常规辅导组在饮食限制方面无显著差异。然而,与传统咨询组(n=84)相比,移动训练组在整个期间报告的呼吸困难较少(P= 0.01), 6个月时的饮食限制较少(P= 0.045),术后3个月的负面身体形象较少(P= 0.04)。基于年龄、性别和手术类型的探索性亚组分析表明,更年轻的患者(结论:尽管该试验在术后1个月的饮食限制方面没有显示出显著差异,但在某些尺度上,与传统咨询相比,通过移动应用程序进行的人工指导与胃切除术后胃癌患者的症状更少有关。这种干预可能会帮助病人控制他们的症状并适应他们的饮食。试验注册:ClinicalTrials.gov NCT04394585;https://clinicaltrials.gov/study/NCT04394585。
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引用次数: 0
Effectiveness of mHealth Interventions to Improve Follow-Up and Management Among Solid Organ Transplant Recipients: Systematic Review and Meta-Analysis. 移动健康干预改善实体器官移植受者随访和管理的有效性:系统回顾和荟萃分析。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-17 DOI: 10.2196/69795
Xiaohong Lin, Haiya Sun, Jiaxin Fang, Zhufeng Han, Zhenshan Ding, Jianding Guo, Lei Dong, Xiangru Li, Hongxia Liu
<p><strong>Background: </strong>Effective follow-up and management after organ transplantation are crucial for transplant recipients. Mobile health (mHealth) interventions have emerged as a significant approach for facilitating follow-up and management. However, there is a lack of systematic reviews and meta-analyses of their effectiveness.</p><p><strong>Objective: </strong>This study aimed to systematically review and synthesize evidence regarding the effectiveness of mHealth interventions in enhancing follow-up and management for transplant recipients.</p><p><strong>Methods: </strong>This study included both randomized controlled trials (RCTs) and nonrandomized studies of interventions (NRSIs) that compared the effects of mHealth interventions with usual care in transplant recipients by searching PubMed, Web of Science, Scopus, Embase, CINAHL, and CENTRAL from database inception to June 2025. The primary outcomes included self-care ability, medical regimen adherence, self-monitoring, communication and counseling, medication adherence, physical activity, nutrition, all-cause mortality, complications, rehospitalization, and emergency and outpatient department visits. The risk of bias for each study was assessed using version 2 of the Cochrane risk-of-bias tool for RCTs and the Risk of Bias in Nonrandomized Studies of Interventions tool for NRSIs. Data extraction and quality assessment were conducted by 2 reviewers independently. Data synthesis was conducted using Review Manager. Both a meta-analysis and a narrative synthesis were carried out.</p><p><strong>Results: </strong>A total of 23 studies (n=15, 65% RCTs and n=8, 35% NRSIs) with 2022 transplant recipients were included. Compared to the control group, mHealth interventions significantly improved self-care ability (mean difference 14.49, 95% CI 9.61-19.36; P<.001) and reduced rehospitalization (odds ratio [OR] 0.49, 95% CI 0.34-0.71; P<.001). The meta-analysis demonstrated no statistically significant difference in mortality rates (OR 0.73, 95% CI 0.39-1.35; P=.31), rejection (OR 0.55, 95% CI 0.25-1.19; P=.13), or infection (OR 0.33, 95% CI 0.06-1.82; P=.20) between the mHealth intervention and control groups. The narrative synthesis indicated that mHealth interventions could effectively promote adherence to medical regimens and medications, facilitate self-monitoring, and improve communication and consultation.</p><p><strong>Conclusions: </strong>mHealth interventions significantly improved self-care ability and reduced rehospitalization rates among organ transplant recipients. However, these interventions did not demonstrate a significant effect on all-cause mortality or complications. mHealth interventions showed potential benefits for various self-management behaviors in organ transplant recipients, but these findings need to be further verified. Future research should prioritize high-quality studies that investigate the impact of mHealth on physical activity, nutrition, and other patien
背景:器官移植后有效的随访和管理对移植受者至关重要。移动保健(mHealth)干预措施已成为促进后续行动和管理的重要方法。然而,缺乏对其有效性的系统评价和荟萃分析。目的:本研究旨在系统回顾和综合有关移动健康干预措施在加强移植受者随访和管理方面有效性的证据。方法:本研究包括随机对照试验(rct)和非随机干预研究(NRSIs),通过检索PubMed、Web of Science、Scopus、Embase、CINAHL和CENTRAL数据库,从数据库建立到2025年6月,比较移动健康干预与移植受者常规护理的效果。主要结局包括自我护理能力、医疗方案依从性、自我监测、沟通和咨询、药物依从性、身体活动、营养、全因死亡率、并发症、再住院、急诊和门诊就诊。每项研究的偏倚风险均采用Cochrane rct风险偏倚工具和非随机干预研究工具进行评估。数据提取和质量评价由2名审稿人独立完成。使用Review Manager进行数据综合。进行了meta分析和叙事综合。结果:共纳入23项研究(n=15, 65% rct和n=8, 35% NRSIs),共2022例移植受者。与对照组相比,移动健康干预显著提高了自我保健能力(平均差值14.49,95% CI 9.61-19.36);结论:移动健康干预显著提高了器官移植受者的自我保健能力,降低了再住院率。然而,这些干预措施并未显示出对全因死亡率或并发症的显著影响。移动健康干预显示了器官移植受者各种自我管理行为的潜在益处,但这些发现需要进一步验证。未来的研究应优先考虑高质量的研究,调查移动健康对身体活动、营养和其他以患者为中心的结果的影响。试验注册:国际注册系统评价和荟萃分析协议平台INPLASY202480101;https://inplasy.com/inplasy-2024-8-0101/.International注册报告标识符(irrid): RR2-10.37766/inplasy2024.8.0101。
{"title":"Effectiveness of mHealth Interventions to Improve Follow-Up and Management Among Solid Organ Transplant Recipients: Systematic Review and Meta-Analysis.","authors":"Xiaohong Lin, Haiya Sun, Jiaxin Fang, Zhufeng Han, Zhenshan Ding, Jianding Guo, Lei Dong, Xiangru Li, Hongxia Liu","doi":"10.2196/69795","DOIUrl":"10.2196/69795","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Effective follow-up and management after organ transplantation are crucial for transplant recipients. Mobile health (mHealth) interventions have emerged as a significant approach for facilitating follow-up and management. However, there is a lack of systematic reviews and meta-analyses of their effectiveness.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to systematically review and synthesize evidence regarding the effectiveness of mHealth interventions in enhancing follow-up and management for transplant recipients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This study included both randomized controlled trials (RCTs) and nonrandomized studies of interventions (NRSIs) that compared the effects of mHealth interventions with usual care in transplant recipients by searching PubMed, Web of Science, Scopus, Embase, CINAHL, and CENTRAL from database inception to June 2025. The primary outcomes included self-care ability, medical regimen adherence, self-monitoring, communication and counseling, medication adherence, physical activity, nutrition, all-cause mortality, complications, rehospitalization, and emergency and outpatient department visits. The risk of bias for each study was assessed using version 2 of the Cochrane risk-of-bias tool for RCTs and the Risk of Bias in Nonrandomized Studies of Interventions tool for NRSIs. Data extraction and quality assessment were conducted by 2 reviewers independently. Data synthesis was conducted using Review Manager. Both a meta-analysis and a narrative synthesis were carried out.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 23 studies (n=15, 65% RCTs and n=8, 35% NRSIs) with 2022 transplant recipients were included. Compared to the control group, mHealth interventions significantly improved self-care ability (mean difference 14.49, 95% CI 9.61-19.36; P&lt;.001) and reduced rehospitalization (odds ratio [OR] 0.49, 95% CI 0.34-0.71; P&lt;.001). The meta-analysis demonstrated no statistically significant difference in mortality rates (OR 0.73, 95% CI 0.39-1.35; P=.31), rejection (OR 0.55, 95% CI 0.25-1.19; P=.13), or infection (OR 0.33, 95% CI 0.06-1.82; P=.20) between the mHealth intervention and control groups. The narrative synthesis indicated that mHealth interventions could effectively promote adherence to medical regimens and medications, facilitate self-monitoring, and improve communication and consultation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;mHealth interventions significantly improved self-care ability and reduced rehospitalization rates among organ transplant recipients. However, these interventions did not demonstrate a significant effect on all-cause mortality or complications. mHealth interventions showed potential benefits for various self-management behaviors in organ transplant recipients, but these findings need to be further verified. Future research should prioritize high-quality studies that investigate the impact of mHealth on physical activity, nutrition, and other patien","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"13 ","pages":"e69795"},"PeriodicalIF":6.2,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12756658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Fit Between the Outputs of Freely Available Medication Adherence Apps and Users' Needs: Mixed Methods Study. 探索免费药物依从性应用程序输出与用户需求之间的契合度:混合方法研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-16 DOI: 10.2196/68919
Kirstin Messner, Vanessa Sutter, Samuel Allemann, Isabelle Arnet
<p><strong>Background: </strong>Medication nonadherence is a significant barrier to therapy success. Smartphone apps represent reasonable tools for simple adherence-enhancing interventions. Many adherence apps are available in app stores with diverse content, quality, and outputs. We define "output of an adherence app" as the processing and visualization of data recorded by the user and related to adherence. In 2016, Santo et al defined 5 desirable features in the output of adherence apps: tracking history, charts, statistics, rewards, and an exportable file. With this, a reference point to evaluate outputs of adherence apps was delivered. Identifying and fulfilling users' needs are essential when developing an adherence app for patients' self-management and professional adherence services, such as therapy support provided by health care professionals (HCPs).</p><p><strong>Objective: </strong>We aimed to investigate the smartphone app market regarding desirable features in the outputs, explore the users' needs, and evaluate the concordance.</p><p><strong>Methods: </strong>We searched for smartphone adherence apps in the 2 largest commercial app repositories by using keywords. Search results were screened for eligibility by applying inclusion and exclusion criteria. Eligible, freely available apps were tested regarding desirable features in their output. We conducted 2 focus groups and a cross-sectional online survey to explore users' needs. Survey participants rated their desire for features on a 7-point Likert scale. Focus groups were analyzed using the previously reported framework method. Descriptive statistics were calculated by median and IQR or mean and SD. We compared survey subgroups with a 2-tailed t test. A P value <.05 was considered statistically significant.</p><p><strong>Results: </strong>We screened 80 apps for eligibility and included 9 in our analyses. All desirable features were present, with tracking history being the most frequent feature (in 8/9 apps). Other desirable features were observed in 3 or fewer of the apps. Eight individuals participated in the 2 focus groups. During the focus groups, a total of 13 categories of desired features emerged. All 5 desirable features were rated as important in adherence apps. Three additional features were mentioned: (1) professional feedback regarding therapy or intake course, (2) additional recommendations based on intake course, and (3) option to discuss the data with an HCP. A total of 42 individuals participated in the online survey. Tracking history was the most desired (mean rating of 5.29) and rewards the least desired feature (mean rating of 2.81) in the output. There was ambivalence regarding professional feedback, statistics, and charts. Participants with or without regular medication use showed no significant differences.</p><p><strong>Conclusions: </strong>The outputs delivered by freely available smartphone adherence apps only partly match users' needs. Users showed a speci
背景:药物依从性是治疗成功的一个重要障碍。智能手机应用程序是简单的增强依从性干预的合理工具。应用商店中有许多具有不同内容、质量和输出的坚持应用程序。我们将“依从应用的输出”定义为对用户记录的与依从相关的数据进行处理和可视化。2016年,Santo等人定义了坚持应用输出中的5个理想功能:跟踪历史、图表、统计、奖励和可导出文件。由此,提供了一个评估依从性应用程序输出的参考点。在为患者自我管理和专业依从性服务(如卫生保健专业人员提供的治疗支持)开发依从性应用程序时,确定和满足用户需求至关重要。目的:我们旨在调查智能手机应用市场中输出的理想功能,探索用户需求,并评估一致性。方法:我们使用关键词在2个最大的商业应用程序库中搜索智能手机粘附应用程序。通过应用纳入和排除标准筛选搜索结果的合格性。对合格的、免费的应用程序进行了测试,以确定其输出中的理想功能。我们进行了两个焦点小组和一个横断面在线调查,以探索用户的需求。调查参与者以7分的李克特量表为自己对特征的渴望打分。使用先前报道的框架方法对焦点小组进行分析。描述性统计采用中位数和IQR或平均值和SD计算。我们用双尾t检验比较调查亚组。结果:我们筛选了80个应用程序,并将其中9个纳入我们的分析。所有理想的功能都出现了,跟踪历史记录是最常见的功能(在8/9的应用程序中)。其他令人满意的功能在3个或更少的应用程序中被观察到。8个人参加了两个焦点小组。在焦点小组讨论期间,总共出现了13类期望的功能。在坚持应用程序中,所有5个理想功能都被评为重要的。另外三个特征被提到:(1)关于治疗或摄入过程的专业反馈,(2)基于摄入过程的额外建议,(3)与HCP讨论数据的选项。共有42人参与了在线调查。跟踪历史是最理想的(平均评分5.29),奖励输出中最不理想的特征(平均评分2.81)。对于专业的反馈、统计数据和图表,存在矛盾心理。服用或不服用常规药物的参与者没有显著差异。结论:免费提供的智能手机依从性应用程序提供的输出仅部分满足用户需求。用户对使用HCP解释他们的数据表现出特别的兴趣。因此,依从性应用程序不能替代HCP,但可以用于增强当前患者的护理。
{"title":"Exploring the Fit Between the Outputs of Freely Available Medication Adherence Apps and Users' Needs: Mixed Methods Study.","authors":"Kirstin Messner, Vanessa Sutter, Samuel Allemann, Isabelle Arnet","doi":"10.2196/68919","DOIUrl":"10.2196/68919","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Medication nonadherence is a significant barrier to therapy success. Smartphone apps represent reasonable tools for simple adherence-enhancing interventions. Many adherence apps are available in app stores with diverse content, quality, and outputs. We define \"output of an adherence app\" as the processing and visualization of data recorded by the user and related to adherence. In 2016, Santo et al defined 5 desirable features in the output of adherence apps: tracking history, charts, statistics, rewards, and an exportable file. With this, a reference point to evaluate outputs of adherence apps was delivered. Identifying and fulfilling users' needs are essential when developing an adherence app for patients' self-management and professional adherence services, such as therapy support provided by health care professionals (HCPs).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;We aimed to investigate the smartphone app market regarding desirable features in the outputs, explore the users' needs, and evaluate the concordance.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We searched for smartphone adherence apps in the 2 largest commercial app repositories by using keywords. Search results were screened for eligibility by applying inclusion and exclusion criteria. Eligible, freely available apps were tested regarding desirable features in their output. We conducted 2 focus groups and a cross-sectional online survey to explore users' needs. Survey participants rated their desire for features on a 7-point Likert scale. Focus groups were analyzed using the previously reported framework method. Descriptive statistics were calculated by median and IQR or mean and SD. We compared survey subgroups with a 2-tailed t test. A P value &lt;.05 was considered statistically significant.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;We screened 80 apps for eligibility and included 9 in our analyses. All desirable features were present, with tracking history being the most frequent feature (in 8/9 apps). Other desirable features were observed in 3 or fewer of the apps. Eight individuals participated in the 2 focus groups. During the focus groups, a total of 13 categories of desired features emerged. All 5 desirable features were rated as important in adherence apps. Three additional features were mentioned: (1) professional feedback regarding therapy or intake course, (2) additional recommendations based on intake course, and (3) option to discuss the data with an HCP. A total of 42 individuals participated in the online survey. Tracking history was the most desired (mean rating of 5.29) and rewards the least desired feature (mean rating of 2.81) in the output. There was ambivalence regarding professional feedback, statistics, and charts. Participants with or without regular medication use showed no significant differences.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The outputs delivered by freely available smartphone adherence apps only partly match users' needs. Users showed a speci","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"13 ","pages":"e68919"},"PeriodicalIF":6.2,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12754584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145767945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility and Preliminary Effectiveness of a Mobile App-Based Personalized Exercise Program in Older Patients With Chronic Knee Osteoarthritis: Pilot Randomized Controlled Trial. 基于移动应用程序的个性化运动方案在老年慢性膝骨关节炎患者中的可行性和初步效果:随机对照试验。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-16 DOI: 10.2196/71073
Yu Jin Im, Jihong Choi, Sol-A Choi, Jeong-Yi Kwon, Jong Geol Do

Background: Knee osteoarthritis is a prevalent cause of disability among older adults, emphasizing the need for effective and accessible self-management strategies. Mobile app-based personalized exercise programs predominantly overcome the barriers associated with traditional approaches.

Objective: This study aimed to evaluate the feasibility and preliminary efficacy of a 6-week mobile app-based self-exercise program that incorporates a multimonitoring system, weekly progress tracking, and dynamic exercise adjustments used by physiotherapists, and compares them with those of a conventional paper-based self-exercise program in older patients with chronic knee osteoarthritis.

Methods: A total of 29 participants aged ≥60 years with chronic knee pain and radiographic evidence of osteoarthritis were randomized at a 2:1 ratio to either the intervention (19/29, 66%; mobile app-based program) or control (10/29, 34%; paper-based program) group. The mobile app delivered a personalized exercise program, which was tailored by physiotherapists based on remote monitoring of patient-reported symptoms. Feasibility outcomes included retention, adherence, and satisfaction rates, as well as safety. Preliminary clinical outcomes included changes from baseline to 6 weeks in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total score, Numeric Rating Scale (NRS) pain, and other functional measures.

Results: A total of 26 participants (n=16, 62% intervention and n=10, 38% control) completed the 6-week assessment, with retention rates of 84% and 100%, respectively. No adverse events were reported. Adherence was high in the intervention group, with 69% exercising ≥5 days per week and 88% reporting high satisfaction. The intervention group exhibited significant reductions in the WOMAC total score (median change -11.00, 95% CI -23.00 to -2.50; P=.01) and NRS pain score (mean change -2.12, 95% CI -3.13 to -1.11; P<.001).

Conclusions: The mobile app-based personalized exercise program was feasible, safe, and well-accepted among older patients with knee osteoarthritis. High adherence and satisfaction support the practicality of this approach, and preliminary improvements in pain and function suggest potential clinical benefit. A larger, adequately powered trial is warranted to confirm the effectiveness of digital self-exercise interventions for knee osteoarthritis management.

背景:膝关节骨性关节炎是老年人致残的普遍原因,强调需要有效和可及的自我管理策略。基于移动应用的个性化锻炼计划主要克服了与传统方法相关的障碍。目的:本研究旨在评估一项为期6周的基于移动应用程序的自我锻炼计划的可行性和初步效果,该计划包括多监测系统、每周进度跟踪和物理治疗师使用的动态运动调整,并将其与传统的基于纸张的自我锻炼计划进行比较。方法:共有29名年龄≥60岁的慢性膝关节疼痛和骨关节炎影像学证据的参与者按2:1的比例随机分为干预组(19/29,66%;基于移动应用程序的方案)或对照组(10/29,34%;基于纸张的方案)。移动应用程序提供了一个个性化的锻炼计划,由物理治疗师根据患者报告的症状远程监测量身定制。可行性结果包括保留、依从性、满意度以及安全性。初步临床结果包括西安大略省和麦克马斯特大学骨关节炎指数(WOMAC)总分、数字评定量表(NRS)疼痛和其他功能测量从基线到6周的变化。结果:共有26名参与者完成了为期6周的评估,其中干预组为16名,占62%,对照组为10名,占38%,保留率分别为84%和100%。无不良事件报告。干预组的依从性很高,69%的人每周锻炼≥5天,88%的人报告高满意度。干预组WOMAC总分(中位数变化-11.00,95% CI -23.00至-2.50;P= 0.01)和NRS疼痛评分(中位数变化-2.12,95% CI -3.13至-1.11;P)显著降低。结论:基于移动应用程序的个性化运动方案在老年膝关节骨性关节炎患者中是可行、安全且被广泛接受的。高依从性和满意度支持了这种方法的实用性,并且疼痛和功能的初步改善表明了潜在的临床益处。有必要进行更大规模、更有力的试验,以证实数字化自我锻炼干预对膝关节骨关节炎管理的有效性。
{"title":"Feasibility and Preliminary Effectiveness of a Mobile App-Based Personalized Exercise Program in Older Patients With Chronic Knee Osteoarthritis: Pilot Randomized Controlled Trial.","authors":"Yu Jin Im, Jihong Choi, Sol-A Choi, Jeong-Yi Kwon, Jong Geol Do","doi":"10.2196/71073","DOIUrl":"10.2196/71073","url":null,"abstract":"<p><strong>Background: </strong>Knee osteoarthritis is a prevalent cause of disability among older adults, emphasizing the need for effective and accessible self-management strategies. Mobile app-based personalized exercise programs predominantly overcome the barriers associated with traditional approaches.</p><p><strong>Objective: </strong>This study aimed to evaluate the feasibility and preliminary efficacy of a 6-week mobile app-based self-exercise program that incorporates a multimonitoring system, weekly progress tracking, and dynamic exercise adjustments used by physiotherapists, and compares them with those of a conventional paper-based self-exercise program in older patients with chronic knee osteoarthritis.</p><p><strong>Methods: </strong>A total of 29 participants aged ≥60 years with chronic knee pain and radiographic evidence of osteoarthritis were randomized at a 2:1 ratio to either the intervention (19/29, 66%; mobile app-based program) or control (10/29, 34%; paper-based program) group. The mobile app delivered a personalized exercise program, which was tailored by physiotherapists based on remote monitoring of patient-reported symptoms. Feasibility outcomes included retention, adherence, and satisfaction rates, as well as safety. Preliminary clinical outcomes included changes from baseline to 6 weeks in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total score, Numeric Rating Scale (NRS) pain, and other functional measures.</p><p><strong>Results: </strong>A total of 26 participants (n=16, 62% intervention and n=10, 38% control) completed the 6-week assessment, with retention rates of 84% and 100%, respectively. No adverse events were reported. Adherence was high in the intervention group, with 69% exercising ≥5 days per week and 88% reporting high satisfaction. The intervention group exhibited significant reductions in the WOMAC total score (median change -11.00, 95% CI -23.00 to -2.50; P=.01) and NRS pain score (mean change -2.12, 95% CI -3.13 to -1.11; P<.001).</p><p><strong>Conclusions: </strong>The mobile app-based personalized exercise program was feasible, safe, and well-accepted among older patients with knee osteoarthritis. High adherence and satisfaction support the practicality of this approach, and preliminary improvements in pain and function suggest potential clinical benefit. A larger, adequately powered trial is warranted to confirm the effectiveness of digital self-exercise interventions for knee osteoarthritis management.</p>","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"13 ","pages":"e71073"},"PeriodicalIF":6.2,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145767948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tailoring mHealth for Healthy Aging: Focus Group Study With Retirement-Age Adults. 为健康老龄化量身定制移动医疗:针对退休年龄成年人的焦点小组研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-15 DOI: 10.2196/70051
Paula Collazo-Castiñeira, Rocío Rodríguez-Rey, Alfonso J Cruz-Jentoft, Somaya Ben Allouch, Doris Eglseer, Josje Schoufour, Eva Topinková, Peter J M Weijs, Yves Boirie, Macarena Sánchez-Izquierdo

Background: The adoption of mobile health (mHealth) technologies among older adults remains significantly lower than in younger populations, despite their potential to promote healthier lifestyles and mitigate age-related health risks.

Objective: This study aims to explore the perspectives of retirement-age adults on mHealth interventions, identifying factors that influence their adoption, such as persuasive elements in the app design and psychological techniques.

Methods: A qualitative focus group study was conducted with 19 Spanish participants recruited from urban community settings in Madrid, Spain (mean age 61.5 years; 15/19, 79% women). Participants discussed their attitudes, barriers, and preferences for mHealth tools. Focus groups were recorded, transcribed, and coded using an iterative process to ensure rigorous data analysis. An abductive approach was followed, using the persuasive design principles framework and the behavior change techniques' taxonomy, and representing any theme outside those frameworks.

Results: Participants expressed generally positive attitudes toward mHealth tools, favoring intuitive, user-friendly designs that are minimally time-demanding. However, significant barriers also emerged, such as low digital literacy and concerns about technology dependence. Key design preferences (persuasive design principles) and psychological techniques (behavior change techniques) were deemed beneficial, with preferred features such as tailored and meaningful goal-setting, self-monitoring, positive feedback (eg, congratulating messages after achieving a goal; social rewards), and a moderated use of notifications and prompts. Participants also stressed the importance of age-appropriate recommendations (eg, suggested diets for their age and characteristics) and design (eg, accessible, easy-to-use interfaces and human-like communication). Additionally, some preferences appeared to be culturally grounded (eg, rejection of anglicisms and the desire for locally relevant content, such as suggested activities specific to Madrid). Social support mechanisms, such as group activities and peer interactions through mHealth, were seen as critical for fostering motivation and engagement.

Conclusions: mHealth interventions for this population should offer accessible and easy-to-use interfaces along with initial tutorials, facilitating an easy onboarding to overcome low digital literacy, thereby enhancing both usability and initial adoption. Furthermore, by providing meaningful, tailored content (eg, personalized diets and goals) and social features that foster peer connection (eg, user chats or organized activities), these tools may better support sustained engagement over time.

背景:尽管移动医疗(mHealth)技术有可能促进更健康的生活方式并减轻与年龄相关的健康风险,但老年人对移动医疗(mHealth)技术的采用仍明显低于年轻人。目的:本研究旨在探讨退休年龄成年人对移动医疗干预的看法,确定影响其采用的因素,如应用程序设计中的说服因素和心理技巧。方法:从西班牙马德里的城市社区招募19名西班牙参与者进行定性焦点小组研究(平均年龄61.5岁;15/19,79%为女性)。与会者讨论了他们对移动医疗工具的态度、障碍和偏好。使用迭代过程对焦点小组进行记录、转录和编码,以确保严格的数据分析。采用诱导性方法,使用劝导式设计原则框架和行为改变技术的分类法,并表示这些框架之外的任何主题。结果:参与者普遍对移动医疗工具持积极态度,倾向于直观、用户友好的设计,且时间要求最低。然而,也出现了重大障碍,例如低数字素养和对技术依赖的担忧。关键的设计偏好(有说服力的设计原则)和心理技巧(行为改变技巧)被认为是有益的,首选的功能包括量身定制和有意义的目标设定、自我监控、积极反馈(例如,实现目标后的祝贺信息、社会奖励),以及适度使用通知和提示。与会者还强调了与年龄相适应的建议(例如,针对他们的年龄和特征提出的饮食建议)和设计(例如,可访问的、易于使用的界面和人性化的沟通)的重要性。此外,一些偏好似乎是有文化基础的(例如,拒绝使用英语和希望提供与当地相关的内容,例如建议的马德里特定活动)。社会支持机制,如小组活动和通过移动医疗进行的同伴互动,被视为促进动机和参与的关键。结论:针对这一人群的移动医疗干预措施应提供可访问和易于使用的界面以及初始教程,促进易于上手,以克服数字素养低的问题,从而提高可用性和初始采用率。此外,通过提供有意义的、量身定制的内容(例如,个性化的饮食和目标)和促进同伴联系的社交功能(例如,用户聊天或有组织的活动),这些工具可能会更好地支持长期的持续参与。
{"title":"Tailoring mHealth for Healthy Aging: Focus Group Study With Retirement-Age Adults.","authors":"Paula Collazo-Castiñeira, Rocío Rodríguez-Rey, Alfonso J Cruz-Jentoft, Somaya Ben Allouch, Doris Eglseer, Josje Schoufour, Eva Topinková, Peter J M Weijs, Yves Boirie, Macarena Sánchez-Izquierdo","doi":"10.2196/70051","DOIUrl":"10.2196/70051","url":null,"abstract":"<p><strong>Background: </strong>The adoption of mobile health (mHealth) technologies among older adults remains significantly lower than in younger populations, despite their potential to promote healthier lifestyles and mitigate age-related health risks.</p><p><strong>Objective: </strong>This study aims to explore the perspectives of retirement-age adults on mHealth interventions, identifying factors that influence their adoption, such as persuasive elements in the app design and psychological techniques.</p><p><strong>Methods: </strong>A qualitative focus group study was conducted with 19 Spanish participants recruited from urban community settings in Madrid, Spain (mean age 61.5 years; 15/19, 79% women). Participants discussed their attitudes, barriers, and preferences for mHealth tools. Focus groups were recorded, transcribed, and coded using an iterative process to ensure rigorous data analysis. An abductive approach was followed, using the persuasive design principles framework and the behavior change techniques' taxonomy, and representing any theme outside those frameworks.</p><p><strong>Results: </strong>Participants expressed generally positive attitudes toward mHealth tools, favoring intuitive, user-friendly designs that are minimally time-demanding. However, significant barriers also emerged, such as low digital literacy and concerns about technology dependence. Key design preferences (persuasive design principles) and psychological techniques (behavior change techniques) were deemed beneficial, with preferred features such as tailored and meaningful goal-setting, self-monitoring, positive feedback (eg, congratulating messages after achieving a goal; social rewards), and a moderated use of notifications and prompts. Participants also stressed the importance of age-appropriate recommendations (eg, suggested diets for their age and characteristics) and design (eg, accessible, easy-to-use interfaces and human-like communication). Additionally, some preferences appeared to be culturally grounded (eg, rejection of anglicisms and the desire for locally relevant content, such as suggested activities specific to Madrid). Social support mechanisms, such as group activities and peer interactions through mHealth, were seen as critical for fostering motivation and engagement.</p><p><strong>Conclusions: </strong>mHealth interventions for this population should offer accessible and easy-to-use interfaces along with initial tutorials, facilitating an easy onboarding to overcome low digital literacy, thereby enhancing both usability and initial adoption. Furthermore, by providing meaningful, tailored content (eg, personalized diets and goals) and social features that foster peer connection (eg, user chats or organized activities), these tools may better support sustained engagement over time.</p>","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"13 ","pages":"e70051"},"PeriodicalIF":6.2,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12750076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145762921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Refined Mobile Health Intervention (SMARTFAMILY2.0) to Promote Physical Activity and Healthy Eating in a Family Setting: Randomized Controlled Trial. 在家庭环境中促进身体活动和健康饮食的精细移动健康干预(SMARTFAMILY2.0):随机对照试验
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-15 DOI: 10.2196/65558
Janis Fiedler, Kathrin Wunsch, Sebastian Hubenschmid, Harald Reiterer, Britta Renner, Alexander Woll
<p><strong>Background: </strong>Many mobile health (mHealth) apps focus on promoting physical activity (PA) and healthy eating (HE). However, there is limited empirical evidence regarding their effectiveness in initiating and sustaining behavior change, particularly among children and adolescents. Considering that behavior is influenced by social contexts, it is essential to take core settings like family dynamics into account when designing mHealth apps.</p><p><strong>Objective: </strong>The purpose of this study was to further develop and refine the SMARTFAMILY (SF) app targeting PA and HE in a collective family-based setting by enhancing design and usability, as well as by adding gamification aspects, health literacy, and just-in-time adaptive interventions to the first version of the app.</p><p><strong>Methods: </strong>The SF2.0 app, based on behavior change theories and techniques, was developed, implemented, and evaluated. The app was used in a collective family setting, with family members using it individually and cooperatively. In a cluster-randomized controlled trial, the intervention group (IG) used the app for 3 consecutive weeks, while the control group (CG) received no treatment. Primary outcomes included PA measured through self-reports and accelerometry, as well as self-reported fruit and vegetable intake (FVI) for HE. Secondary outcomes included intrinsic motivation, behavior-specific self-efficacy, and the Family Health Climate. A follow-up assessment (T<sub>2</sub>) was conducted 4 weeks after the postmeasurement (T<sub>1</sub>) to assess intervention effects. Multilevel analyses were performed in R (R Foundation for Statistical Computing), considering the hierarchical structure of individuals (level 1) within families (level 2).</p><p><strong>Results: </strong>Overall, 55 families (28 CG, 105/209; 27 IG, 104/209 participants) were recruited for the study. In total, 3 families (3 CG, n=12) chose to drop out of the study due to personal reasons before T<sub>0</sub>. Overall, no evidence for meaningful and statistically significant increases in PA was observed in favor of the IG of our physically active sample. However, the app elucidated positive effects in favor of the IG for FVI diary (T<sub>0</sub>-T<sub>1</sub>; P=.03), joint PA (T<sub>0</sub>-T<sub>1</sub>; P=.02 and T<sub>0</sub>-T<sub>2</sub>; P<.001), and joint family meals (T<sub>0</sub>-T<sub>1</sub>; P=.004).</p><p><strong>Conclusions: </strong>The SF2.0 trial evaluated an mHealth intervention designed to promote PA and HE within families. Despite incorporating a theoretical foundation, several behavior change techniques based on family life, and gamification and just-in-time adaptive intervention features, the intervention did not significantly increase PA levels among physically active participants. FVI, joint PA, and joint meals were improved within the IG. Previous studies on digital health interventions have produced mixed results, and family-based mHealth inter
背景:许多移动健康(mHealth)应用程序专注于促进身体活动(PA)和健康饮食(HE)。然而,关于它们在启动和维持行为改变方面的有效性,特别是在儿童和青少年中,经验证据有限。考虑到行为受到社会环境的影响,在设计移动健康应用程序时,必须考虑到家庭动态等核心环境。目的:本研究的目的是进一步开发和完善SMARTFAMILY (SF)应用程序,通过增强设计和可用性,以及在第一版应用程序中添加游戏化方面,健康素养和及时适应性干预措施,以集体家庭为基础的环境中针对PA和HE。方法:基于行为改变理论和技术的SF2.0应用程序开发,实施和评估。该应用程序是在一个集体家庭环境中使用的,家庭成员单独或合作地使用它。在一项集群随机对照试验中,干预组(IG)连续3周使用该应用程序,而对照组(CG)不接受任何治疗。主要结果包括通过自我报告和加速度计测量的PA,以及自我报告的HE水果和蔬菜摄入量(FVI)。次要结果包括内在动机、特定行为的自我效能感和家庭健康氛围。在测量后4周(T1)进行随访评估(T2)以评估干预效果。在R (R Foundation for Statistical Computing)中进行了多水平分析,考虑了家庭(水平2)中个体(水平1)的层次结构。结果:总共有55个家庭(28个CG, 105/209; 27个IG, 104/209)被纳入研究。在T0之前,共有3个家庭(3个CG, n=12)因个人原因选择退出研究。总的来说,没有观察到有意义的和统计学上显著的PA增加的证据,有利于我们的体力活动样本的IG。然而,该应用程序阐明了IG对FVI日记(T0-T1; P= 0.03),关节PA (T0-T1; P= 0.02和T0-T2; P0-T1; P= 0.004)的积极作用。结论:SF2.0试验评估了旨在促进家庭PA和HE的移动健康干预。尽管结合了理论基础,基于家庭生活的几种行为改变技术,以及游戏化和及时适应性干预的特征,干预并没有显著增加体力活动参与者的PA水平。IG内FVI、关节PA、关节膳食均有改善。以前关于数字健康干预的研究产生了不同的结果,基于家庭的移动健康干预仍然很少,对整个家庭行为和随机对照试验的关注有限。为了提高干预效果,未来的应用开发可以考虑加入更高级的功能,并应该关注不活跃的参与者。需要进一步的研究来更好地了解干预参与和为初级预防工作量身定制移动健康方法。试验注册:德国临床试验注册中心DRKS00010415;https://www.drks.de/search/en/trial/DRKS00010415.International注册报告标识符(irrid): RR2-10.2196/20534。
{"title":"A Refined Mobile Health Intervention (SMARTFAMILY2.0) to Promote Physical Activity and Healthy Eating in a Family Setting: Randomized Controlled Trial.","authors":"Janis Fiedler, Kathrin Wunsch, Sebastian Hubenschmid, Harald Reiterer, Britta Renner, Alexander Woll","doi":"10.2196/65558","DOIUrl":"10.2196/65558","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Many mobile health (mHealth) apps focus on promoting physical activity (PA) and healthy eating (HE). However, there is limited empirical evidence regarding their effectiveness in initiating and sustaining behavior change, particularly among children and adolescents. Considering that behavior is influenced by social contexts, it is essential to take core settings like family dynamics into account when designing mHealth apps.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;The purpose of this study was to further develop and refine the SMARTFAMILY (SF) app targeting PA and HE in a collective family-based setting by enhancing design and usability, as well as by adding gamification aspects, health literacy, and just-in-time adaptive interventions to the first version of the app.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The SF2.0 app, based on behavior change theories and techniques, was developed, implemented, and evaluated. The app was used in a collective family setting, with family members using it individually and cooperatively. In a cluster-randomized controlled trial, the intervention group (IG) used the app for 3 consecutive weeks, while the control group (CG) received no treatment. Primary outcomes included PA measured through self-reports and accelerometry, as well as self-reported fruit and vegetable intake (FVI) for HE. Secondary outcomes included intrinsic motivation, behavior-specific self-efficacy, and the Family Health Climate. A follow-up assessment (T&lt;sub&gt;2&lt;/sub&gt;) was conducted 4 weeks after the postmeasurement (T&lt;sub&gt;1&lt;/sub&gt;) to assess intervention effects. Multilevel analyses were performed in R (R Foundation for Statistical Computing), considering the hierarchical structure of individuals (level 1) within families (level 2).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Overall, 55 families (28 CG, 105/209; 27 IG, 104/209 participants) were recruited for the study. In total, 3 families (3 CG, n=12) chose to drop out of the study due to personal reasons before T&lt;sub&gt;0&lt;/sub&gt;. Overall, no evidence for meaningful and statistically significant increases in PA was observed in favor of the IG of our physically active sample. However, the app elucidated positive effects in favor of the IG for FVI diary (T&lt;sub&gt;0&lt;/sub&gt;-T&lt;sub&gt;1&lt;/sub&gt;; P=.03), joint PA (T&lt;sub&gt;0&lt;/sub&gt;-T&lt;sub&gt;1&lt;/sub&gt;; P=.02 and T&lt;sub&gt;0&lt;/sub&gt;-T&lt;sub&gt;2&lt;/sub&gt;; P&lt;.001), and joint family meals (T&lt;sub&gt;0&lt;/sub&gt;-T&lt;sub&gt;1&lt;/sub&gt;; P=.004).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The SF2.0 trial evaluated an mHealth intervention designed to promote PA and HE within families. Despite incorporating a theoretical foundation, several behavior change techniques based on family life, and gamification and just-in-time adaptive intervention features, the intervention did not significantly increase PA levels among physically active participants. FVI, joint PA, and joint meals were improved within the IG. Previous studies on digital health interventions have produced mixed results, and family-based mHealth inter","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"13 ","pages":"e65558"},"PeriodicalIF":6.2,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12750077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145762893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the Quality and Features of Visual Acuity Apps Using the Mobile App Rating Scale: Systematic Review. 使用移动应用程序评分量表评估视觉敏锐度应用程序的质量和特征:系统回顾。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-12 DOI: 10.2196/65997
P Connor Lentz, Emily Dorairaj, Pranav Vasu, Isabella Wagner, Jaxson Jeffery, Farha Deceus, Nithya Boopathiraj, Yazan Abubaker, Darby D Miller, Antonio Jorge Forte, Syril Dorairaj

Background: Mobile visual acuity (VA) apps have emerged as valuable tools in both clinical and home settings, particularly in the context of expanding teleophthalmology. Despite the growing number of apps available to measure visual acuity, studies evaluating their overall quality, functionality, and clinical relevance are limited.

Objective: This study aimed to systematically evaluate the quality and features of mobile VA apps available on iOS and Android platforms using the clinically validated Mobile App Rating Scale (MARS).

Methods: A comprehensive search of the Google Play Store and Apple App Store was conducted between January 2024 and March 2024 using standardized search terms. Eligible apps included free, English-language VA testing tools not requiring external devices. App characteristics and features were extracted. Each app was independently evaluated by 2 trained reviewers using MARS, which rates engagement, functionality, aesthetics, information quality, and subjective quality on a 5-point scale.

Results: Of the 725 apps initially identified, 44 met the inclusion criteria, with 23 from the Google Play Store and 21 from the Apple App Store. The most common VA test optotypes used were Tumbling E (n=21; 48%), Snellen Chart (18/44; 41%), and Landolt C (n=14; 32%). Common supplemental features included color vision testing (n=20; 46%), astigmatism tests (n=13; 30%), Amsler grid (n=13; 30%), and contrast testing (n=12; 28%). The average MARS scores were comparable across platforms: 3.04 (SD 0.80) for Android and 3.02 (SD 0.84) for iOS. Functionality received the highest ratings (mean 3.65, SD 0.75 for Android; mean 3.71, SD 0.82 for iOS), while subjective quality received the lowest (mean 2.09, SD 1.01 for Android; mean 2.21, SD 1.01 for iOS). Few apps had undergone clinical validation. Only Apple App Store apps demonstrated significant correlations between MARS scores and app store star ratings.

Conclusions: VA apps exhibited considerable heterogeneity in quality, functionality, and clinical use. Total mean MARS scores were similar between the Google Play Store and the Apple App Store, suggesting that neither platform consistently offers superior app quality. While many apps are technically sound, low subjective-quality scores and a lack of clinical validation limit their current use in professional practice. These findings underscore the need for more rigorous app development and validation standards to improve their relevance and reliability in teleophthalmology.

背景:移动视力(VA)应用程序已经成为临床和家庭环境中有价值的工具,特别是在远程眼科不断扩大的背景下。尽管越来越多的应用程序可用于测量视力,但评估其整体质量,功能和临床相关性的研究是有限的。目的:本研究旨在使用临床验证的移动应用评定量表(MARS)系统评估iOS和Android平台上可用的移动VA应用的质量和功能。方法:在2024年1月至2024年3月期间,使用标准化搜索词对谷歌Play Store和Apple App Store进行综合搜索。合格的应用程序包括免费的英语VA测试工具,不需要外部设备。提取App特征和特征。每个应用程序都由2名训练有素的评论者使用MARS进行独立评估,MARS将用户粘性、功能、美学、信息质量和主观质量分为5个等级。结果:在最初确定的725款应用中,有44款符合纳入标准,其中23款来自bb0 Play Store, 21款来自Apple App Store。最常用的VA测试视型是翻滚E (n=21; 48%)、Snellen Chart(18/44; 41%)和Landolt C (n=14; 32%)。常见的补充功能包括色视觉测试(n=20; 46%)、散光测试(n=13; 30%)、Amsler网格测试(n=13; 30%)和对比度测试(n=12; 28%)。不同平台的平均MARS分数具有可比性:Android为3.04 (SD 0.80), iOS为3.02 (SD 0.84)。功能评分最高(Android平均3.65,SD 0.75; iOS平均3.71,SD 0.82),主观质量评分最低(Android平均2.09,SD 1.01; iOS平均2.21,SD 1.01)。很少有应用程序经过临床验证。只有苹果App Store应用显示出MARS分数与应用商店星级评级之间的显著相关性。结论:VA应用程序在质量、功能和临床使用方面表现出相当大的异质性。bb0 Play Store和苹果App Store的总平均MARS分数相似,这表明这两个平台的应用质量都不高。虽然许多应用程序在技术上是合理的,但主观质量得分低,缺乏临床验证,限制了它们目前在专业实践中的使用。这些发现强调需要更严格的应用程序开发和验证标准,以提高其在远程眼科中的相关性和可靠性。
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引用次数: 0
Effectiveness of Internet-Based Cognitive Behavioral Therapy for Depressive Symptoms During Pregnancy by Using Real-World Data: Retrospective Cohort Study. 基于网络的认知行为治疗妊娠期抑郁症状的有效性:回顾性队列研究
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-12-11 DOI: 10.2196/73512
Asuka Takae, Natsu Sasaki, Kotaro Imamura, Daisuke Nishi

Background: Approximately 1 out of 5 pregnant women develops depression. Internet-based cognitive behavioral therapy (iCBT) is an effective way to treat not only depression but also mild depressive symptoms or subthreshold depression. While numerous iCBT programs have been developed and tested through randomized controlled trials for various mental health conditions and specific populations, research on their effectiveness and application in the real world remains limited.

Objective: This study aimed to examine the effectiveness of a previously developed iCBT program implemented in an existing app for improving depressive symptoms among pregnant women in a real-world setting.

Methods: The previously developed iCBT program for preventing perinatal depression was already implemented in an existing app called Luna Luna Baby by MTI Ltd. The app aims to provide information to pregnant women about pregnancy and babies, and potential users can download it from the Japanese version of the Apple App Store or Google Play Store without any fee. The program does not require any additional fees. The log data stored on the app identified iCBT program users and nonusers, allowing us to conduct this retrospective cohort study. Data from September 2022 to September 2024 were extracted from the app after anonymous processing. The primary outcome was the score on the self-reported Edinburgh Postnatal Depression Scale (EPDS), which participants answer by themselves on the app. The exposure group was defined as completers of all 6 modules of the iCBT program. The nonexposure group was defined as users who did not use any module of the program and matched the baseline characteristics of the exposure group. The change in EPDS score before and after using the program was compared using effect sizes, and repeated 2-way ANOVA was conducted to test the difference between the exposure and nonexposure groups.

Results: Data from 119 women who completed the iCBT program and 448 pair-matched controls were selected. The average EPDS scores at baseline were 7.24 (SD 5.30) in the exposure group and 7.25 (SD 5.18) in the nonexposure group. After using the iCBT program, the group mean EPDS scores changed by -0.69 (SD 4.92) and +0.99 (SD 5.56) over time in the exposure and nonexposure groups, respectively (Cohen d=0.31, 95% CI 0.11-0.51). The repeated 2-way ANOVA showed statistical significance in the interaction terms between the groups and the measurement time points (P=.04).

Conclusions: The previously developed iCBT program showed a significant effect with a modest effect size on decreasing depressive symptoms among pregnant women in a real-world setting. Future research should attempt to minimize dropouts and increase participation in the program.

背景:大约五分之一的孕妇患有抑郁症。基于网络的认知行为疗法(iCBT)不仅是治疗抑郁症的有效方法,而且也是治疗轻度抑郁症状或阈下抑郁症的有效方法。尽管针对各种心理健康状况和特定人群的随机对照试验已经开发和测试了许多iCBT项目,但对其有效性和在现实世界中的应用的研究仍然有限。目的:本研究旨在检验先前开发的iCBT程序在现有应用程序中实施的有效性,以改善现实世界中孕妇的抑郁症状。方法:之前开发的iCBT预防围产期抑郁症的程序已经在MTI有限公司现有的Luna Luna Baby应用程序中实施。该应用旨在为孕妇提供有关怀孕和婴儿的信息,潜在用户可以从日本版的苹果应用商店或谷歌Play商店免费下载。该计划不需要任何额外费用。存储在应用程序上的日志数据识别了iCBT程序的用户和非用户,使我们能够进行这项回顾性队列研究。从2022年9月到2024年9月的数据经过匿名处理后从应用程序中提取。主要结果是参与者在应用程序上自行报告的爱丁堡产后抑郁量表(EPDS)的分数。暴露组被定义为完成iCBT计划的所有6个模块。非暴露组定义为不使用任何程序模块且符合暴露组基线特征的用户。应用效应量比较应用程序前后EPDS评分的变化,并采用重复双因素方差分析(repeated two -way ANOVA)检验暴露组与非暴露组的差异。结果:数据来自119名完成iCBT项目的妇女和448名配对对照者。暴露组EPDS基线平均评分为7.24 (SD 5.30),非暴露组为7.25 (SD 5.18)。使用iCBT程序后,暴露组和非暴露组EPDS平均评分随时间的变化分别为-0.69 (SD 4.92)和+0.99 (SD 5.56) (Cohen d=0.31, 95% CI 0.11-0.51)。重复双因素方差分析显示,组间相互作用项和测量时间点间差异有统计学意义(P= 0.04)。结论:先前开发的iCBT项目在现实世界中显示出显著的效果,但效果大小适中,可以减轻孕妇的抑郁症状。未来的研究应尽量减少辍学率,并增加对该计划的参与。
{"title":"Effectiveness of Internet-Based Cognitive Behavioral Therapy for Depressive Symptoms During Pregnancy by Using Real-World Data: Retrospective Cohort Study.","authors":"Asuka Takae, Natsu Sasaki, Kotaro Imamura, Daisuke Nishi","doi":"10.2196/73512","DOIUrl":"10.2196/73512","url":null,"abstract":"<p><strong>Background: </strong>Approximately 1 out of 5 pregnant women develops depression. Internet-based cognitive behavioral therapy (iCBT) is an effective way to treat not only depression but also mild depressive symptoms or subthreshold depression. While numerous iCBT programs have been developed and tested through randomized controlled trials for various mental health conditions and specific populations, research on their effectiveness and application in the real world remains limited.</p><p><strong>Objective: </strong>This study aimed to examine the effectiveness of a previously developed iCBT program implemented in an existing app for improving depressive symptoms among pregnant women in a real-world setting.</p><p><strong>Methods: </strong>The previously developed iCBT program for preventing perinatal depression was already implemented in an existing app called Luna Luna Baby by MTI Ltd. The app aims to provide information to pregnant women about pregnancy and babies, and potential users can download it from the Japanese version of the Apple App Store or Google Play Store without any fee. The program does not require any additional fees. The log data stored on the app identified iCBT program users and nonusers, allowing us to conduct this retrospective cohort study. Data from September 2022 to September 2024 were extracted from the app after anonymous processing. The primary outcome was the score on the self-reported Edinburgh Postnatal Depression Scale (EPDS), which participants answer by themselves on the app. The exposure group was defined as completers of all 6 modules of the iCBT program. The nonexposure group was defined as users who did not use any module of the program and matched the baseline characteristics of the exposure group. The change in EPDS score before and after using the program was compared using effect sizes, and repeated 2-way ANOVA was conducted to test the difference between the exposure and nonexposure groups.</p><p><strong>Results: </strong>Data from 119 women who completed the iCBT program and 448 pair-matched controls were selected. The average EPDS scores at baseline were 7.24 (SD 5.30) in the exposure group and 7.25 (SD 5.18) in the nonexposure group. After using the iCBT program, the group mean EPDS scores changed by -0.69 (SD 4.92) and +0.99 (SD 5.56) over time in the exposure and nonexposure groups, respectively (Cohen d=0.31, 95% CI 0.11-0.51). The repeated 2-way ANOVA showed statistical significance in the interaction terms between the groups and the measurement time points (P=.04).</p><p><strong>Conclusions: </strong>The previously developed iCBT program showed a significant effect with a modest effect size on decreasing depressive symptoms among pregnant women in a real-world setting. Future research should attempt to minimize dropouts and increase participation in the program.</p>","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"13 ","pages":"e73512"},"PeriodicalIF":6.2,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12741654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145742733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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JMIR mHealth and uHealth
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