Pub Date : 2025-02-01DOI: 10.1016/j.jfo.2024.104373
Y. Rivoal , A. Miguel , H. Bailleul , M. Canino , S. Bacon , G. Saint-Lorant , É. Deloison , J.-C. Quintyn
<div><div>Dry eye syndrome is a multifactorial disease with a complex pathophysiology. The associated morbidity is a worldwide public health problem. The development of autologous serum-based eye drops is an interesting treatment but presents some constraints. This is a retrospective, observational, single-center study of 43 patients (73 eyes) treated with autologous serum-based eye drops for dry eye syndrome at the University Hospital of Caen between 2014 and 2023. The patients’ subjective symptoms, as well as the various modalities of evaluation of their daily quality of life were collected using questionnaires inspired by the OSDI questionnaire. The other elements used in this study were reported from the patients’ medical files. We observed a mean improvement in quality of life of 44% in the treated subjects. Quality of life correlates with the improvement in the subject's quality of life score and overall health (<em>P</em> <!--><<!--> <!-->0.01) but, nevertheless, depends on the severity of the initial clinical damage and the presence or absence of a corneal ulcer (<em>P</em> <!-->=<!--> <!-->0.013). We also found a reduction in the number of daily drops (65.4%) and an improvement in daily activities (85.1%). This study's results are consistent with previous work reporting the efficacy of autologous serum on the quality of life of treated patients. Consideration of the patient as a whole, integrating quality of life assessment with clinical examination, is essential when dealing with dry eye and its innovative therapeutics.</div></div><div><div>Le syndrome de l’œil sec est une maladie multifactorielle avec une pathophysiologie complexe. La morbidité associée est un problème de santé publique mondial. Le développement de gouttes oculaires à base de sérum autologue est un traitement intéressant, mais présente certaines contraintes. Il s’agit d’une étude rétrospective et d’observation, menée dans un seul centre, portant sur 43 patients (73 yeux) traités avec des gouttes oculaires à base de sérum autologue pour le syndrome de l’œil sec à l’hôpital universitaire de Caen entre 2014 et 2023. Les symptômes subjectifs des patients, ainsi que les différentes modalités d’évaluation de leur qualité de vie quotidienne, ont été recueillis à l’aide de questionnaires inspirés du questionnaire OSDI. Les autres éléments utilisés dans cette étude ont été rapportés à partir des dossiers médicaux des patients. Nous avons observé une amélioration moyenne de la qualité de vie de 44 % chez les sujets traités. La qualité de vie est corrélée avec l’amélioration du score de qualité de vie des sujets et de leur santé globale (<em>p</em> <!--><<!--> <!-->0,01), mais dépend néanmoins de la gravité des lésions cliniques initiales et de la présence ou de l’absence d’un ulcère cornéen (<em>p</em> <!-->=<!--> <!-->0,013). Nous avons également constaté une réduction du nombre de gouttes administrées quotidiennement (65,4 %) et une amélioration des activités quotidienne
{"title":"Study of quality of life in patients treated with autologous serum eye drops","authors":"Y. Rivoal , A. Miguel , H. Bailleul , M. Canino , S. Bacon , G. Saint-Lorant , É. Deloison , J.-C. Quintyn","doi":"10.1016/j.jfo.2024.104373","DOIUrl":"10.1016/j.jfo.2024.104373","url":null,"abstract":"<div><div>Dry eye syndrome is a multifactorial disease with a complex pathophysiology. The associated morbidity is a worldwide public health problem. The development of autologous serum-based eye drops is an interesting treatment but presents some constraints. This is a retrospective, observational, single-center study of 43 patients (73 eyes) treated with autologous serum-based eye drops for dry eye syndrome at the University Hospital of Caen between 2014 and 2023. The patients’ subjective symptoms, as well as the various modalities of evaluation of their daily quality of life were collected using questionnaires inspired by the OSDI questionnaire. The other elements used in this study were reported from the patients’ medical files. We observed a mean improvement in quality of life of 44% in the treated subjects. Quality of life correlates with the improvement in the subject's quality of life score and overall health (<em>P</em> <!--><<!--> <!-->0.01) but, nevertheless, depends on the severity of the initial clinical damage and the presence or absence of a corneal ulcer (<em>P</em> <!-->=<!--> <!-->0.013). We also found a reduction in the number of daily drops (65.4%) and an improvement in daily activities (85.1%). This study's results are consistent with previous work reporting the efficacy of autologous serum on the quality of life of treated patients. Consideration of the patient as a whole, integrating quality of life assessment with clinical examination, is essential when dealing with dry eye and its innovative therapeutics.</div></div><div><div>Le syndrome de l’œil sec est une maladie multifactorielle avec une pathophysiologie complexe. La morbidité associée est un problème de santé publique mondial. Le développement de gouttes oculaires à base de sérum autologue est un traitement intéressant, mais présente certaines contraintes. Il s’agit d’une étude rétrospective et d’observation, menée dans un seul centre, portant sur 43 patients (73 yeux) traités avec des gouttes oculaires à base de sérum autologue pour le syndrome de l’œil sec à l’hôpital universitaire de Caen entre 2014 et 2023. Les symptômes subjectifs des patients, ainsi que les différentes modalités d’évaluation de leur qualité de vie quotidienne, ont été recueillis à l’aide de questionnaires inspirés du questionnaire OSDI. Les autres éléments utilisés dans cette étude ont été rapportés à partir des dossiers médicaux des patients. Nous avons observé une amélioration moyenne de la qualité de vie de 44 % chez les sujets traités. La qualité de vie est corrélée avec l’amélioration du score de qualité de vie des sujets et de leur santé globale (<em>p</em> <!--><<!--> <!-->0,01), mais dépend néanmoins de la gravité des lésions cliniques initiales et de la présence ou de l’absence d’un ulcère cornéen (<em>p</em> <!-->=<!--> <!-->0,013). Nous avons également constaté une réduction du nombre de gouttes administrées quotidiennement (65,4 %) et une amélioration des activités quotidienne","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 2","pages":"Article 104373"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-29DOI: 10.1016/j.jfo.2024.104414
B Terefenko, A-M Bron, C Conese, I Ben Ghezala, L Arnould, C Creuzot-Garcher, P-H Gabrielle
{"title":"[Ophthalmic artery occlusion after facial autologous fat injection].","authors":"B Terefenko, A-M Bron, C Conese, I Ben Ghezala, L Arnould, C Creuzot-Garcher, P-H Gabrielle","doi":"10.1016/j.jfo.2024.104414","DOIUrl":"https://doi.org/10.1016/j.jfo.2024.104414","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":"104414"},"PeriodicalIF":1.2,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-24DOI: 10.1016/j.jfo.2025.104427
Ar Coisne
{"title":"[Video of the treatment of late postoperative capsular bag distension syndrome with Nd:YAG laser capsulotomy].","authors":"Ar Coisne","doi":"10.1016/j.jfo.2025.104427","DOIUrl":"https://doi.org/10.1016/j.jfo.2025.104427","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143038966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-24DOI: 10.1016/j.jfo.2024.104405
P Larco, C Mercado, G Amescua
{"title":"Simple limbal epithelial transplantation (SLET) from a monozygotic twin for a severe bilateral chemical burn.","authors":"P Larco, C Mercado, G Amescua","doi":"10.1016/j.jfo.2024.104405","DOIUrl":"https://doi.org/10.1016/j.jfo.2024.104405","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":"104405"},"PeriodicalIF":1.2,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143038968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-22DOI: 10.1016/j.jfo.2024.104416
A Escale, G Bula, P Labalette, M de Massary
{"title":"Postoperative central ulceration of a dermis-fat graft in an anophthalmic socket.","authors":"A Escale, G Bula, P Labalette, M de Massary","doi":"10.1016/j.jfo.2024.104416","DOIUrl":"https://doi.org/10.1016/j.jfo.2024.104416","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":"104416"},"PeriodicalIF":1.2,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-21DOI: 10.1016/j.jfo.2024.104413
J Jacquemart, M Carémé, A Mekerke, P Labalette
{"title":"[Type II arteriovenous communication in a child with KBG syndrome].","authors":"J Jacquemart, M Carémé, A Mekerke, P Labalette","doi":"10.1016/j.jfo.2024.104413","DOIUrl":"https://doi.org/10.1016/j.jfo.2024.104413","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10DOI: 10.1016/j.jfo.2024.104412
T Boutaj, H Lazaar, S Ragala, R Benkirane, L Sbai, O El Korno, O Boukhlouf, S Moutamani, S El Moussaoui, R El Hachimi, A Amazouzi, M Boulaadas, S Tachfouti, O Cherkaoui
{"title":"[Kearns-Sayre Syndrome: A case report in Rabat University Hospital Center and literature review].","authors":"T Boutaj, H Lazaar, S Ragala, R Benkirane, L Sbai, O El Korno, O Boukhlouf, S Moutamani, S El Moussaoui, R El Hachimi, A Amazouzi, M Boulaadas, S Tachfouti, O Cherkaoui","doi":"10.1016/j.jfo.2024.104412","DOIUrl":"https://doi.org/10.1016/j.jfo.2024.104412","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":"104412"},"PeriodicalIF":1.2,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10DOI: 10.1016/j.jfo.2024.104403
N. Yesilirmak , S. Yuzbasioglu , O. Saritas , A. Aktas , J.-L. Bourges
<div><h3>Objective</h3><div>To compare the corneal topographic parameters and ocular surface parameters of ocular rosacea (OR) patients across skin subtypes of the disease and healthy controls.</div></div><div><h3>Methods</h3><div>This prospective study included 180 eyes of 90 OR patients and 60 eyes of 30 healthy controls. Among the OR patients, 30 had phymatous (60 eyes), 30 had erythematotelangiectatic (60 eyes) and 30 had papulopustular skin types (60 eyes). We measured the mean keratometry (Kmean), maximum keratometry (Kmax), thinnest corneal thickness (TCT), central corneal thickness (CCT) and corneal volume (CV) with a topography device (Sirius, Italy). Additionally, we measured tear-film breakup time (TBUT), Meiboscore and Schirmer's test from all participants. We compared parameters across OR skin groups as well as with controls.</div></div><div><h3>Results</h3><div>Kmean and Kmax were significantly steeper in the OR group compared to controls (<em>p</em> <!--><<!--> <!-->0.05). We found significant correlations between “Kmean-Kmax”, “CV-TCT”, “CV-CCT”, and “TCT-CCT” in both groups, while significant correlations between “age-Kmean”, “age-Kmax”, and “Meiboscore-Kmax” were present only in OR patients. When patients were divided into subgroups according to their skin subtypes, the papulopustular and phymatous subgroups had steeper Kmean and Kmax compared to the erythematotelangiectatic and control groups (<em>P</em> <!--><<!--> <!-->0.05). The papulopustular subgroup had lower CCT, lower TBUT and higher Meiboscore compared to the phymatous, erythematotelangiectatic and control groups but lower TCT compared to controls (<em>P</em> <!--><<!--> <!-->0.05). In addition, there were significant correlations between “Kmax-CV”, “Kmax-TCT”, and “Kmax-meiboscore” only in the papulopustular subgroup (<em>P</em> <!--><<!--> <!-->0.05).</div></div><div><h3>Conclusion</h3><div>It appears that the corneas of OR patients are steeper than those of healthy controls; corneal thinning and abnormalities of ocular surface parameters are more pronounced in papulopustular skin types.</div></div><div><h3>Objectif</h3><div>Comparer les paramètres topographiques cornéens et les paramètres de la surface oculaire des patients atteints de rosacée oculaire (RO) selon les sous-types cutanés de la maladie et des témoins sains.</div></div><div><h3>Méthodes</h3><div>Cette étude prospective a inclus 180 yeux de 90 patients RO et 60 yeux de 30 témoins sains. Parmi les patients RO, 30 avaient une peau phymateuse (60 yeux), 30 une peau érythémato-télangiectasique (60 yeux) et 30 une peau papulo-pustuleuse (60 yeux). Nous avons mesuré la kératométrie moyenne (Kmean), la kératométrie maximale (Kmax), l’épaisseur cornéenne la plus fine (TCT), l’épaisseur cornéenne centrale (CCT) et le volume cornéen (CV) avec un appareil topographique (Sirius, Italie). De plus, nous avons mesuré le temps de rupture des larmes (TBUT), le meiboscore et faire le test de Schirmer de tous l
{"title":"Investigation of corneal topographic and ocular surface parameters in ocular rosacea based on skin subtypes","authors":"N. Yesilirmak , S. Yuzbasioglu , O. Saritas , A. Aktas , J.-L. Bourges","doi":"10.1016/j.jfo.2024.104403","DOIUrl":"10.1016/j.jfo.2024.104403","url":null,"abstract":"<div><h3>Objective</h3><div>To compare the corneal topographic parameters and ocular surface parameters of ocular rosacea (OR) patients across skin subtypes of the disease and healthy controls.</div></div><div><h3>Methods</h3><div>This prospective study included 180 eyes of 90 OR patients and 60 eyes of 30 healthy controls. Among the OR patients, 30 had phymatous (60 eyes), 30 had erythematotelangiectatic (60 eyes) and 30 had papulopustular skin types (60 eyes). We measured the mean keratometry (Kmean), maximum keratometry (Kmax), thinnest corneal thickness (TCT), central corneal thickness (CCT) and corneal volume (CV) with a topography device (Sirius, Italy). Additionally, we measured tear-film breakup time (TBUT), Meiboscore and Schirmer's test from all participants. We compared parameters across OR skin groups as well as with controls.</div></div><div><h3>Results</h3><div>Kmean and Kmax were significantly steeper in the OR group compared to controls (<em>p</em> <!--><<!--> <!-->0.05). We found significant correlations between “Kmean-Kmax”, “CV-TCT”, “CV-CCT”, and “TCT-CCT” in both groups, while significant correlations between “age-Kmean”, “age-Kmax”, and “Meiboscore-Kmax” were present only in OR patients. When patients were divided into subgroups according to their skin subtypes, the papulopustular and phymatous subgroups had steeper Kmean and Kmax compared to the erythematotelangiectatic and control groups (<em>P</em> <!--><<!--> <!-->0.05). The papulopustular subgroup had lower CCT, lower TBUT and higher Meiboscore compared to the phymatous, erythematotelangiectatic and control groups but lower TCT compared to controls (<em>P</em> <!--><<!--> <!-->0.05). In addition, there were significant correlations between “Kmax-CV”, “Kmax-TCT”, and “Kmax-meiboscore” only in the papulopustular subgroup (<em>P</em> <!--><<!--> <!-->0.05).</div></div><div><h3>Conclusion</h3><div>It appears that the corneas of OR patients are steeper than those of healthy controls; corneal thinning and abnormalities of ocular surface parameters are more pronounced in papulopustular skin types.</div></div><div><h3>Objectif</h3><div>Comparer les paramètres topographiques cornéens et les paramètres de la surface oculaire des patients atteints de rosacée oculaire (RO) selon les sous-types cutanés de la maladie et des témoins sains.</div></div><div><h3>Méthodes</h3><div>Cette étude prospective a inclus 180 yeux de 90 patients RO et 60 yeux de 30 témoins sains. Parmi les patients RO, 30 avaient une peau phymateuse (60 yeux), 30 une peau érythémato-télangiectasique (60 yeux) et 30 une peau papulo-pustuleuse (60 yeux). Nous avons mesuré la kératométrie moyenne (Kmean), la kératométrie maximale (Kmax), l’épaisseur cornéenne la plus fine (TCT), l’épaisseur cornéenne centrale (CCT) et le volume cornéen (CV) avec un appareil topographique (Sirius, Italie). De plus, nous avons mesuré le temps de rupture des larmes (TBUT), le meiboscore et faire le test de Schirmer de tous l","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 3","pages":"Article 104403"},"PeriodicalIF":1.2,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10DOI: 10.1016/j.jfo.2024.104372
D. Fraenkel , H. Kaymak , M. Hartmann , W. Aljundi , C. Munteanu , B. Seitz , A.D. Abdin
<div><h3>Purpose</h3><div>To investigate the morphologic and functional outcomes of nanosecond subthreshold (ST) laser treatment for patients with chronic central serous chorioretinopathy (CSC).</div></div><div><h3>Methods</h3><div>In this prospective study, 44 patients were treated with the ST nanosecond laser with a follow-up period of 12 months. All target variables were measured at 1, 3, 6 and 12 months after the first laser treatment.</div></div><div><h3>Results</h3><div>This study showed a significant improvement in macular sensitivity (MS), a significant reduction in central macular thickness (CMT) as well as a significant reduction in subretinal fluid height (SRF) after 3 months of treatment. The subfoveal choroidal thickness (SFCT) was significantly reduced after 12 months of treatment. However, the best-corrected visual acuity (BCVA) (logMAR) did not change significantly at any time during the study. A high proportion of patients (85%) showed complete resolution of SRF after 12 months, indicating a positive response to treatment in the majority of our patients.</div></div><div><h3>Conclusion</h3><div>This study showed statistically significant functional improvement in MS as well as significant anatomical reduction in CMT, SFCT and SRF height in CSC patients treated with ST nanosecond laser therapy. Patients with higher SRF at baseline required repeated laser treatments to achieve complete resolution of the SRF.</div></div><div><h3>Objectif</h3><div>Étudier les résultats morphologiques et fonctionnels du traitement au <em>subthreshold</em> (ST) <em>nanolaser</em> pour les patients atteints de choriorétinopathie centrale séreuse chronique (CCS).</div></div><div><h3>Méthodes</h3><div>Dans cette étude prospective, 44 patients ont été traités au ST <em>nanolaser</em> avec une période de suivi de 12 mois. Toutes les variables ont été mesurées à 1, 3, 6 et 12 mois après le premier traitement au laser.</div></div><div><h3>Résultats</h3><div>Cette étude a démontré une amélioration significative de la sensibilité maculaire (SM) et une réduction significative de l’épaisseur maculaire centrale (EMC), ainsi que de la hauteur du liquide sous-rétinien (LSR) après 3 mois de traitement. L’épaisseur choroïdienne sous-fovéale (ECSF) n’a été significativement réduite qu’après 12 mois de traitement. Cependant, la meilleure acuité visuelle corrigée (MAVC) (logMAR) n’a pas changé de manière significative durant l’étude. La majorité des patients (85 %) a montré une résolution complète du LSR après 12 mois, ce qui indique une réponse positive au traitement.</div></div><div><h3>Conclusion</h3><div>Cette étude a démontré une amélioration statistiquement significative de la SM ainsi qu’une réduction significative de l’EMT, de l’ECSF et de la hauteur du LSR chez les patients atteints de CCS traités au ST <em>nanolaser</em>. Les patients présentant un LSR plus élevé au départ ont dû subir plusieurs traitements pour obtenir une résolution complète du LSR.</div></div
{"title":"Subthreshold nanosecond laser therapy for chronic central serous chorioretinopathy: A prospective study","authors":"D. Fraenkel , H. Kaymak , M. Hartmann , W. Aljundi , C. Munteanu , B. Seitz , A.D. Abdin","doi":"10.1016/j.jfo.2024.104372","DOIUrl":"10.1016/j.jfo.2024.104372","url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate the morphologic and functional outcomes of nanosecond subthreshold (ST) laser treatment for patients with chronic central serous chorioretinopathy (CSC).</div></div><div><h3>Methods</h3><div>In this prospective study, 44 patients were treated with the ST nanosecond laser with a follow-up period of 12 months. All target variables were measured at 1, 3, 6 and 12 months after the first laser treatment.</div></div><div><h3>Results</h3><div>This study showed a significant improvement in macular sensitivity (MS), a significant reduction in central macular thickness (CMT) as well as a significant reduction in subretinal fluid height (SRF) after 3 months of treatment. The subfoveal choroidal thickness (SFCT) was significantly reduced after 12 months of treatment. However, the best-corrected visual acuity (BCVA) (logMAR) did not change significantly at any time during the study. A high proportion of patients (85%) showed complete resolution of SRF after 12 months, indicating a positive response to treatment in the majority of our patients.</div></div><div><h3>Conclusion</h3><div>This study showed statistically significant functional improvement in MS as well as significant anatomical reduction in CMT, SFCT and SRF height in CSC patients treated with ST nanosecond laser therapy. Patients with higher SRF at baseline required repeated laser treatments to achieve complete resolution of the SRF.</div></div><div><h3>Objectif</h3><div>Étudier les résultats morphologiques et fonctionnels du traitement au <em>subthreshold</em> (ST) <em>nanolaser</em> pour les patients atteints de choriorétinopathie centrale séreuse chronique (CCS).</div></div><div><h3>Méthodes</h3><div>Dans cette étude prospective, 44 patients ont été traités au ST <em>nanolaser</em> avec une période de suivi de 12 mois. Toutes les variables ont été mesurées à 1, 3, 6 et 12 mois après le premier traitement au laser.</div></div><div><h3>Résultats</h3><div>Cette étude a démontré une amélioration significative de la sensibilité maculaire (SM) et une réduction significative de l’épaisseur maculaire centrale (EMC), ainsi que de la hauteur du liquide sous-rétinien (LSR) après 3 mois de traitement. L’épaisseur choroïdienne sous-fovéale (ECSF) n’a été significativement réduite qu’après 12 mois de traitement. Cependant, la meilleure acuité visuelle corrigée (MAVC) (logMAR) n’a pas changé de manière significative durant l’étude. La majorité des patients (85 %) a montré une résolution complète du LSR après 12 mois, ce qui indique une réponse positive au traitement.</div></div><div><h3>Conclusion</h3><div>Cette étude a démontré une amélioration statistiquement significative de la SM ainsi qu’une réduction significative de l’EMT, de l’ECSF et de la hauteur du LSR chez les patients atteints de CCS traités au ST <em>nanolaser</em>. Les patients présentant un LSR plus élevé au départ ont dû subir plusieurs traitements pour obtenir une résolution complète du LSR.</div></div","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 3","pages":"Article 104372"},"PeriodicalIF":1.2,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10DOI: 10.1016/j.jfo.2024.104411
K Bonińska, S Cisiecki
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