Journal Francais D Ophtalmologie最新文献

{"title":"Physiopathologie et prise en charge des kératites herpétiques liées aux virus herpes simplex résistants à l’aciclovir","authors":"R. Boucher ,&nbsp;D. Boutolleau ,&nbsp;S. Burrel ,&nbsp;O. Haigh ,&nbsp;E. Barreau ,&nbsp;M. Benali ,&nbsp;S. Meziou ,&nbsp;M. Labetoulle ,&nbsp;A. Rousseau","doi":"10.1016/j.jfo.2025.104433","DOIUrl":"10.1016/j.jfo.2025.104433","url":null,"abstract":"<div><div>Les kératites herpétiques (KH) causées par le virus herpes simplex 1 (HSV-1) représentent la cause principale de cécité d’origine infectieuse dans les pays développés. Le traitement actuel repose sur l’usage curatif et préventif d’analogues nucléosidiques acycliques (ANA) anti-herpétiques, en particulier, l’aciclovir (ACV) ou d’autres molécules de même mode d’action. Les KH causées par un virus résistant à l’ACV sont de plus en plus rencontrées en pratique clinique. Leur prise en charge repose sur l’obtention du diagnostic virologique de résistance sur prélèvement oculaire acheminé en laboratoire spécialisé. La caractérisation génotypique par séquençage ADN des enzymes virales cibles des antiviraux permet l’adaptation thérapeutique en fonction de la mutation identifiée. Les mutations de la thymidine kinase (TK) virale sont les plus fréquentes et ne laissent que peu d’alternatives viables pour un traitement prophylactique au long cours parmi les molécules actuellement disponibles sur le marché. L’aménamévir (AMNV), nouvelle molécule ciblant le complexe d’enzymes virales hélicase-primase (HP) et ayant fait ses preuves dans le traitement d’autres localisations herpétiques, a récemment montré son intérêt dans la prise en charge des KH résistantes à l’ACV. Son mécanisme d’action indépendant de la TK lui permet de conserver une activité en cas de résistance avérée à l’ACV.</div></div><div><div>Herpetic keratitis (HK) caused by herpes simplex virus 1 (HSV-1) is the major cause of infection-related blindness in developed countries. Current treatment is based on curative and preventive use of antiherpetic acyclic nucleoside analogues (ANAs), namely acyclovir (ACV) or other molecules with the same mechanism of action. The frequency of HK caused by acyclovir-resistant viruses is steadily increasing. Virological proof of resistance is obtained from an ocular sample sent to a specialized laboratory. Genotypic characterization by DNA sequencing of the viral enzymes targeted by antivirals allows adaptation of treatment according to the mutation identified. Mutations of the viral thymidine kinase (TK) are the most frequent and leave few viable alternatives for long-term prophylactic treatment among currently available drugs. Amenamevir (AMNV), a new drug targeting the viral helicase-primase (HP) enzyme complex, with proven efficacy for treatment of herpetic infections of other sites, has recently shown value in the management of ACV-resistant HK. Its TK-independent mechanism allows it to retain its antiviral activity even in cases of patient resistance to ACV.</div></div>","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 4","pages":"Article 104433"},"PeriodicalIF":1.2,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143419967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal refractive alterations in a case of vaccinia virus-induced nummular keratitis.","authors":"H Choudhry, P Tailor, A Patel, M H Dastjerdi","doi":"10.1016/j.jfo.2025.104437","DOIUrl":"https://doi.org/10.1016/j.jfo.2025.104437","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The watchmaker's eye: Exposure keratopathy with secondary limbal stem cell deficiency due to the use of a loupe","authors":"E. Blavakis ,&nbsp;S. Magnin ,&nbsp;H. Massa ,&nbsp;G. Thumann ,&nbsp;M. Kecik","doi":"10.1016/j.jfo.2025.104444","DOIUrl":"10.1016/j.jfo.2025.104444","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 4","pages":"Article 104444"},"PeriodicalIF":1.2,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143387609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilisation des implants premium chez les patients glaucomateux : conseils de la Société française du glaucome (SFG) et de la Société de l’association française des implants intra-oculaires et de chirurgie réfractive (SAFIR)","authors":"E. Blumen ,&nbsp;A. Denoyer ,&nbsp;A. Grise-Dulac ,&nbsp;A. Rousseau ,&nbsp;C. Schweitzer ,&nbsp;P. Rozot ,&nbsp;F. Aptel","doi":"10.1016/j.jfo.2025.104431","DOIUrl":"10.1016/j.jfo.2025.104431","url":null,"abstract":"<div><div>Les progrès récents des techniques chirurgicales et des implants ont transformé la chirurgie de la cataracte en véritable chirurgie réfractive, permettant à de nombreux patients de se passer de correction optique. Les implants « premium » offrent de multiples options pour corriger les amétropies – y compris l’astigmatisme – et les effets de la presbytie. Bien que la chirurgie de la cataracte soit souvent bénéfique chez les patients glaucomateux, la neuropathie optique glaucomateuse peut altérer la qualité de la vision et affecter les résultats des implants premium, en particulier des implants multifocaux. Cette revue concise propose des recommandations pratiques sur l’utilisation des implants premium en fonction du type, du stade et de l’évolutivité du glaucome, en se basant sur les données scientifiques actuelles. Les implants toriques monofocaux sont envisageables pour corriger l’astigmatisme chez les patients glaucomateux, mais nécessitent une évaluation clinique minutieuse. Les implants « monofocaux plus » et certains implants à profondeur de champ étendue (EDOF) peuvent également être envisagés, avec des précautions spécifiques. Les implants multifocaux diffractifs et réfractifs ne sont pas conseillés en cas de glaucome ou en cas d’hypertonie oculaire avec des facteurs de risque d’évolution vers un glaucome. En conclusion, les indications des implants premium chez les patients glaucomateux doivent faire l’objet d’une sélection rigoureuse et individualisée, et d’explications exhaustives.</div></div><div><div>Recent advances in surgical techniques and intraocular lens implants have transformed cataract surgery into a true refractive procedure, enabling many patients to forgo optical correction. “Premium” IOL's offer multiple options for correcting refractive errors, including astigmatism, and addressing the effects of presbyopia. While cataract surgery is often beneficial for glaucoma patients, glaucomatous optic neuropathy can impair visual quality and impact the outcomes of premium IOL's, particularly multifocal IOL's. This concise review provides practical recommendations for the use of premium IOL's based on the type, stage and progression profile of glaucoma, supported by current scientific data. Monofocal toric IOL's may be considered to correct astigmatism in glaucoma patients but require careful clinical evaluation. “Monofocal plus” IOL's and certain extended depth of focus (EDOF) IOL's may also be viable options, provided that specific precautions are taken. However, diffractive and refractive multifocal IOL's are not recommended for patients with glaucoma or ocular hypertension with risk factors for development of glaucoma. In conclusion, the indications for premium IOL's in glaucoma patients should include rigorous, individualized selection, along with comprehensive patient counseling.</div></div>","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 3","pages":"Article 104431"},"PeriodicalIF":1.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Menkes disease with unilateral lacrimal fistula.","authors":"S Labay-Tejado, H González-Valdivia, E Casas-Gimeno, S Lotz-Esquivel, J Prat-Bartomeu","doi":"10.1016/j.jfo.2025.104441","DOIUrl":"https://doi.org/10.1016/j.jfo.2025.104441","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cataract surgery without preanesthetic consultation: A 2-year retrospective study","authors":"V. Cayzac ,&nbsp;J. Bordes ,&nbsp;B. Valero ,&nbsp;H. Voisin ,&nbsp;M. Sagnard ,&nbsp;J. Bertin ,&nbsp;T. David ,&nbsp;H. El Chehab","doi":"10.1016/j.jfo.2025.104428","DOIUrl":"10.1016/j.jfo.2025.104428","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;div&gt;Cataract surgery is the most commonly performed procedure in the world. However, certain perioperative modalities remain controversial, and the necessity of systematic performance of a preanesthetic consultation is gradually being questioned. The goal of this study was to investigate the anesthetic and surgical safety of performing cataract surgeries under topical or sub-Tenon's anesthesia without prior preanesthetic consultation.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Thus, we conducted a retrospective study at Sainte-Anne Military Teaching Hospital (Toulon, France) over the period from January 1, 2021, to December 31, 2022, including all patients admitted to the operating room for a phacoemulsification procedure performed under topical or sub-Tenon's anesthesia without prior preanesthetic consultation. Patients were referred to this simplified care pathway in the absence of: predictable surgical difficulties, significant anxiety, risk of agitation or claustrophobia, communication difficulties, lack of cooperation, difficulties in maintaining a motionless supine position, coughing or severe dyspnea or severe allergic history. The eligible patients for this care pathway were selected by the surgeon based on a list of indications. The occurrence of systemic or surgical complications, drug interventions, calls to the anesthesiologist, or unplanned hospitalization in the immediate postoperative period was recorded.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;One thousand procedures were performed on 654 patients. No major systemic complications were recorded. Surgical complications occurred in 27 procedures (2.7%). Medication was administered to the patient intraoperatively during 413 (41.3%) procedures, mostly antihypertensive drugs (33.1%) and sedatives (11.5%). Aside from drug prescription, 9 calls (0.9%) were made to the anesthesiologist. There were no unplanned hospitalizations in the immediate postoperative period.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;In our series, performing phacoemulsification procedures under topical or sub-Tenon's anesthesia without prior preanesthetic consultation has shown anesthetic and surgical complication rates comparable to those reported in the literature. Prospective comparative studies are needed to confirm the non-inferiority of this care pathway and to generalize its practice.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objectif&lt;/h3&gt;&lt;div&gt;La chirurgie de la cataracte est l’intervention la plus fréquemment réalisée dans le monde. Cependant, certaines modalités périopératoires restent controversées, et la réalisation systématique d’une consultation préanesthésique est progressivement remise en question. L’objectif de cette étude a été d’évaluer la sécurité anesthésique et chirurgicale de la pratique de phacoémulsifications sous anesthésie topique ou sous-ténonienne sans consultation préanesthésique préalable.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Méthodes&lt;/h3&gt;&lt;div&gt;Il s’agit d’une étude rétrospective, menée à l’hôpital d’instruction de","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 3","pages":"Article 104428"},"PeriodicalIF":1.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumeur vasoproliférative rétinienne (tumeur rétinienne astrocytaire réactionnelle)","authors":"Y.-G. Muller,&nbsp;D. Gaucher","doi":"10.1016/j.jfo.2025.104430","DOIUrl":"10.1016/j.jfo.2025.104430","url":null,"abstract":"&lt;div&gt;&lt;div&gt;La tumeur vasoproliférative rétinienne, autrement appelée tumeur rétinienne astrocytaire réactionnelle, est une entité rare se présentant comme une masse de la périphérie rétinienne inférieure, associée à des anomalies vasculaires, et généralement accompagnée de manifestations exsudatives qui conditionnent le pronostic visuel. L’étiologie précise n’est pas connue, néanmoins, la nature principalement astrocytique et réactionnelle de ces lésions semble désormais établie. Elle est classée en primaire ou secondaire, et de nombreuses affections oculaires associées ont ainsi été rapportées, parmi lesquelles la rétinopathie pigmentaire, la pars planite et la maladie de Coats. Le principal diagnostic différentiel est l’hémangioblastome capillaire rétinien de la maladie de von Hippel-Lindau. Le traitement idéal n’est actuellement pas consensuel, et de nombreuses modalités thérapeutiques ont été décrites sur des séries de cas limitées, avec des taux de succès variables. Un traitement s’impose néanmoins en cas de risque visuel, et repose, en fonction des caractéristiques individuelles de la tumeur, sur une approche combinée et raisonnée des différentes modalités thérapeutiques disponibles. Les traitements conservateurs comme la photocoagulation laser, la cryothérapie et/ou la photothérapie dynamique sont ainsi généralement privilégiés pour les tumeurs de petites tailles, tandis que des traitements plus invasifs comme la curiethérapie seront proposés pour des lésions volumineuses ou dont l’activité exsudative ne parvient pas à être contrôlée. La chirurgie vitréorétinienne est fréquemment nécessaire en cas de complications, telles que les décollements de rétine, les membranes épirétiniennes ou les hémorragies du vitré. Les injections intra-vitréennes d’anti-VEGF sont une thérapeutique adjuvante de l’œdème maculaire fréquemment associé.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;div&gt;Retinal vasoproliferative tumor, otherwise known as retinal reactive astrocytic tumor, is a rare entity presenting as a mass in the inferior peripheral retina, associated with vascular abnormalities, and usually accompanied by exudative manifestations that affect the visual prognosis. The precise etiology is unknown, but the predominantly astrocytic and reactive nature of these lesions now appears to be established. It is classified as primary or secondary, and numerous associated ocular conditions have been reported, including pigmentary retinopathy, pars planitis and Coats’ disease. The main differential diagnosis is the retinal capillary hemangioblastoma in von Hippel-Lindau disease. There is currently no consensus on the ideal treatment, and numerous therapeutic modalities have been described in limited case series, with variable success rates. Nevertheless, treatment is essential when there is a visual risk and is based on a combined, thoughtful approach to the various therapeutic modalities available, depending on the individual characteristics of the tumor. Conservative treatments such as l","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 3","pages":"Article 104430"},"PeriodicalIF":1.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving pressurization of the eye during Descemet's membrane endothelial keratoplasty in patients with glaucoma drainage devices.","authors":"E Fernández López, A Lanzagorta Aresti, C Martínez Gil, J V Piá Ludeña, C Peris Martínez","doi":"10.1016/j.jfo.2025.104443","DOIUrl":"https://doi.org/10.1016/j.jfo.2025.104443","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":"104443"},"PeriodicalIF":1.2,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior ischemic optic neuropathy (PION) after complicated cataract surgery as the first clinical manifestation of carotid artery stenosis.","authors":"P Toumasis, A Tsiogka, K Koulotsiou, G Vlachos, M-E Sotirianakou, I T Tsinopoulos, K Droutsas, E Karmiris","doi":"10.1016/j.jfo.2025.104438","DOIUrl":"https://doi.org/10.1016/j.jfo.2025.104438","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Deferoxamine maculopathy].","authors":"L Barioulet, F Varenne, S Hamid, F-P Roubelat, V Soler","doi":"10.1016/j.jfo.2025.104439","DOIUrl":"https://doi.org/10.1016/j.jfo.2025.104439","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":"104439"},"PeriodicalIF":1.2,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}