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Standardization and Normalization of the Changes in the Sexual Functioning Questionnaire in Male Addicts and a Comparing Male Addict's Sexual Functioning with Normal People 男性成瘾者性功能问卷变化的规范化与规范化及男性成瘾者性功能与正常人的比较
Pub Date : 2017-07-12 DOI: 10.4172/2155-6105.1000334
R. Mirzaei, S. Moradi, H. Haghgoo
The present study aimed to validate the Changes in the Sexual Functioning Questionnaire Short-Form (CSFQ-14) and compare male addict’s sexual functioning to that of normal people. In this study, a causalcomparative design was used. A total of 101 men addicted to one or more substances, from addiction treatment centers in Semnan, and a total of 101 normal men from the staff of Semnan’s Universities were selected using a convenience sampling method. The instrument used in this study was the CSFQ which is a 14-item questionnaire. All the study data were analyzed using SPSS software. An exploratory factor analysis revealed 3 factors: 1) sexual pleasure factor (single-item), 2) mental factor (sexual desire) with a Cronbach’s alpha of 0.90, and 3) physical factor (orgasm and arousal) with a Cronbach’s alpha of 0.92. In addition, the results of a MANOVA analysis comparing the sexual functioning of sex addicts to that of non-addicts indicated significant differences between the two groups in all the three factors. Therefore, the validated instrument can be useful in assessing the changes in sexual functioning. The study results also rejected the claim that drugs can solve sexual problems or lead to a feeling of greater sexual pleasure.
本研究旨在验证《性功能问卷简表》(CSFQ-14)的变化,并比较男性成瘾者与正常人的性功能。本研究采用因果比较设计。采用方便抽样法,从塞姆南戒毒所抽取一种或多种物质成瘾者101名,从塞姆南大学工作人员中抽取正常男性101名。本研究使用的工具是CSFQ,这是一份14题的问卷。所有研究数据均采用SPSS软件进行分析。探索性因子分析显示:性愉悦因子(单项)、心理因子(性欲)(Cronbach’s alpha为0.90)、生理因子(性高潮和性唤起)(Cronbach’s alpha为0.92)。此外,比较性成瘾者和非性成瘾者性功能的方差分析结果表明,两组在所有三个因素上都存在显著差异。因此,经过验证的仪器可用于评估性功能的变化。研究结果也否定了药物可以解决性问题或带来更大性快感的说法。
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引用次数: 0
Prevalence of Cigarette Smoking and Its Associated Risk Factors among Students of Hawassa University, College of Medicine and Health Sciences, 2016 美国哈瓦萨大学医学与健康科学学院学生吸烟情况及相关危险因素调查,2016
Pub Date : 2017-07-11 DOI: 10.4172/2155-6105.1000331
Birhanu Jikamo Bago
Background: Cigarette smoking is a global health risk, causing increased health-care costs and loss of productivity among a number of age groups. Tobacco use in Africa, including Ethiopia, has attracted little attention, including among students. The aim of this study was to determine the prevalence of cigarette smoking and its associated risk factors among students of Hawassa University College of Medicine and Health Science. Methods: An institutional based cross sectional study was conducted to determine the prevalence of cigarette smoking and its associated risk factors among students of Hawassa University College of Medicine and Health Science. The team used systematic random sampling by determining the k value jumping some of the students from source population based on k intervals. The data was cleaned, coded and analyzed using SPSS version 20 and STATA version 12. Multiple logistic regressions were used to identify factors associated with cigarette smoking. Presence of confounders and interaction effects was investigated by computing relative changes on s coefficients at a cut-off point of 15%. Results and conclusion: The prevalence of cigarette smoking among students was 20.6% (95%CI: 0.61, 0.25). Cigarette smoking was significantly associated with students year of education (AOR=6.02; 95% CI: 2.09, 7.35), ever chewing Khat (AOR=20.99; 95% CI: 1.84, 4.3), age at start of smoking (AOR=2.21; 95% CI: 1.23, 6.12), ever drink alcohol (AOR=4.99; 95% CI: 1.02, 2.43) and receiving information about harmful effects of smoking cigarettes (AOR=4.99; 95% CI: 1.02, 2.43). Year of education, health education information, ever chewing Khat, ever drinking alcohol and age at start of smoking were significant factors for cigarette smoking. We recommend that students >20 years old be targeted with health education campaign focused on harmful effects of smoking tobacco.
背景:吸烟是一种全球健康风险,在一些年龄组中造成保健费用增加和生产力损失。在包括埃塞俄比亚在内的非洲,烟草使用几乎没有引起人们的注意,包括在学生中。本研究的目的是确定哈瓦萨大学医学与健康科学学院学生吸烟的流行程度及其相关的危险因素。方法:采用一项基于机构的横断面研究,以确定哈瓦萨大学医学与健康科学学院学生的吸烟患病率及其相关危险因素。该团队采用了系统随机抽样的方法,根据k间隔确定了一些学生从源人群中跳跃的k值。使用SPSS version 20和STATA version 12对数据进行清洗、编码和分析。使用多元逻辑回归来确定与吸烟有关的因素。在15%的临界值处,通过计算s系数的相对变化来研究混杂因素和相互作用效应的存在。结果与结论:学生吸烟率为20.6% (95%CI: 0.61, 0.25)。吸烟与学生受教育年限显著相关(AOR=6.02;95% CI: 2.09, 7.35),曾经咀嚼过阿拉伯茶(AOR=20.99;95% CI: 1.84, 4.3)、开始吸烟年龄(AOR=2.21;95% CI: 1.23, 6.12),从未饮酒(AOR=4.99;95% CI: 1.02, 2.43)和接受吸烟有害影响的信息(AOR=4.99;95% ci: 1.02, 2.43)。受教育年限、健康教育信息、是否咀嚼阿拉伯茶、是否饮酒和开始吸烟年龄是吸烟的显著因素。我们建议针对10至20岁的学生开展健康教育运动,重点关注吸烟的有害影响。
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引用次数: 3
Marijuana: Clinical, Research, Policy 大麻:临床,研究,政策
Pub Date : 2017-07-01 DOI: 10.4172/2155-6105.S11-E137
N. S. Miller
Drug addiction is the newest threat to the youth health and quality of life in global spectrum. World Health Organization (WHO) has been postulated the term ‘Substance abuse’ for such drug addiction related psychotic anomalies, which is taking lives of in an increasing rate. Only in USA, it has been seen in a study by National Center for Health Statistics that, from 2002 to 2015 there was a 2.2-fold increase in the total number of drug overdose deaths, which is a warning concern [1]. Another report has showed that, approximately 200,000 people worldwide die from drug abuse. Hence, control in such abusive use of psychotic drug is the most urgent need of time. Moreover, research and studies are the only way out to cope up the adverse effect of addictive drugs. Keeping that in aim, the present journal of Addictive Research and Therapy is presenting relevant information and providing positive contribution in the knowledge data base for addictive research.
吸毒成瘾是全球范围内对青少年健康和生活质量的最新威胁。世界卫生组织(WHO)将这种与药物成瘾有关的精神异常称为“药物滥用”,这种疾病正在以越来越多的速度夺走生命。仅在美国,美国国家卫生统计中心(National Center for Health Statistics)的一项研究发现,从2002年到2015年,药物过量死亡总人数增加了2.2倍,这是一个值得警惕的问题[1]。另一份报告显示,全世界大约有20万人死于滥用药物。因此,控制这种滥用精神药物是最迫切需要的时间。此外,研究和研究是应对成瘾药物不良影响的唯一途径。本着这一宗旨,本期《成瘾研究与治疗》杂志为成瘾研究提供了相关信息,并为成瘾研究的知识数据库提供了积极的贡献。
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引用次数: 1
Amphetamines: Potent Recreational Drug of Abuse 安非他明:强效娱乐性药物滥用
Pub Date : 2017-06-21 DOI: 10.4172/2155-6105.1000330
M. Uddin, M. Sufian, M. Kabir, Md. Farhad Hossain, M. Nasrullah, Israt Islam, Abdullah Al Mamun, M. Islam, Sayema Khanum
Amphetamines are central nervous system (CNS) stimulants and belong to psychoactive drugs that affect chemicals in the brain, nerves and exert a constant contribution to hyperactivity and impulse control. The communal group of amphetamines comprises amphetamine, dextroamphetamine and methamphetamine. Amphetamines show its action on the mesolimbic dopaminergic reward system by inducing release of dopamine and to some extent norepinephrine, in the synaptic clefts of the nucleus accumbens and other terminal areas. They offer not only a sense of euphoric state, but also addiction. Amphetamines are frequently prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) in children, adolescents and adults, narcolepsy and obesity. At therapeutic doses, amphetamine causes emotional and cognitive effects such as euphoria, change in desire for sex, increased wakefulness, improved cognitive control, etc. The balance of benefit/risk is the main challenge for its clinical use. When overused these medications can be highly addictive, are often diverted from the user to be used as recreational drugs. Adverse effects include anxiety, aggression, headache, insomnia, hyperactivity, palpitations, increased breathing rate, increased blood pressure, tachycardia, arrhythmia, dilated pupils, paranoia, etc. However, at large doses, these drugs may impair cognitive function and induce rapid muscle breakdown. Even higher doses may give rise to hallucinations, paranoia, psychosis and potentially lifethreatening conditions such as convulsions, stroke, kidney failure, etc. The furthermost serious health implications of amphetamine resulting from chronic use are dependence, considered by compulsive drug-seeking and drug use and a phenomenon notorious as amphetamine psychosis. Therefore the objective of this study was to explore the functions of the amphetamines as recreation drug of abuse.
安非他明是中枢神经系统(CNS)兴奋剂,属于精神活性药物,影响大脑和神经中的化学物质,并对多动症和冲动控制发挥持续的作用。常见的安非他明包括安非他明、右安非他明和甲基苯丙胺。安非他明通过诱导伏隔核和其他末端区域的突触间隙释放多巴胺和一定程度上的去甲肾上腺素,对中边缘多巴胺能奖励系统起作用。它们不仅给人一种欣快的感觉,还会让人上瘾。安非他明经常用于治疗儿童、青少年和成人的注意力缺陷多动障碍(ADHD)、嗜睡症和肥胖症。在治疗剂量下,安非他明会引起情绪和认知方面的影响,如欣快感、性欲望的改变、清醒程度的提高、认知控制能力的改善等。其临床应用面临的主要挑战是利益/风险的平衡。当过度使用这些药物时,这些药物会很容易上瘾,经常被转移到使用者身上,用作娱乐性药物。副作用包括焦虑、攻击性、头痛、失眠、多动、心悸、呼吸频率增加、血压升高、心动过速、心律失常、瞳孔扩大、偏执等。然而,在大剂量下,这些药物可能会损害认知功能并导致快速肌肉分解。甚至更高的剂量也可能引起幻觉、偏执、精神病和潜在的危及生命的情况,如抽搐、中风、肾衰竭等。长期使用安非他明造成的最严重的健康影响是依赖,即强迫性寻求药物和使用药物,以及臭名昭著的安非他明精神病现象。因此,本研究的目的是探讨安非他明作为滥用的娱乐药物的功能。
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引用次数: 7
Prospective, Longitudinal Study to Evaluate the Clinical Utility of a Predictive Algorithm to Detect Opioid Use Disorder in Chronic Pain Patients 评估预测算法在慢性疼痛患者中检测阿片类药物使用障碍的临床应用的前瞻性纵向研究
Pub Date : 2017-06-09 DOI: 10.4172/2155-6105.1000329
Katrina Lewis, Chee Lee, J. Blanchard, S. Kantorovich, B. Meshkin, Ashley Brenton
A prospective, longitudinal study was conducted to determine the clinical utility of an algorithm-based precision medicine profile designed to assess risk associated with opioid use disorder in 5,315 patients in a clinical setting. Specifically, we sought to assess how physicians were using the profile and how its use affected patient outcomes. Ninety percent of all clinicians surveyed reported some benefit to their patient care, with the most utilization for changing the prescribed opioid and the most significant benefits from discontinuing opioids. Patients who received profile-guided care reported on average a 42% reduction in pain, and almost 40% of patients had >50% reduction in pain.
进行了一项前瞻性纵向研究,以确定基于算法的精准医学概况的临床效用,该概况旨在评估临床环境中5,315例阿片类药物使用障碍相关风险。具体来说,我们试图评估医生是如何使用档案的,以及它的使用如何影响患者的预后。接受调查的所有临床医生中,有90%的人报告说,他们对病人的护理有一些好处,其中改变处方阿片类药物的利用率最高,停止使用阿片类药物的好处最大。接受概况指导护理的患者报告疼痛平均减轻42%,近40%的患者疼痛减轻>50%。
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引用次数: 0
Shared Medical Appointments Role in the Opioid Epidemic Era: A Tool forIntegration of Care 共享医疗预约在阿片类药物流行时代的作用:整合护理的工具
Pub Date : 2017-06-02 DOI: 10.4172/2155-6105.1000328
A. M. Daum, Héctor Colón-Rivera, S. Nykiel
Medical visits encompass multiple medical issues, leaving little time to address substance use disorder issues, such as medication-assisted treatment (MAT) for opioid use disorders (OUD). This becomes a barrier to expanding Office-Based Opioid Treatment (OBOT), as many physicians express concern about treating high-risk patients under the current time constrained treatment model. Evidence shows that shared medical appointments (SMAs) are effective treatment models that increase health outcomes and are well received by patients. Research studies that come from primary care where large patient panels and limited access have necessitated the creation of innovative and efficient care delivery. Substance use disorders (SUDs) are chronic diseases comparable to diabetes and hypertension with similar treatment outcomes. Group therapy is well established as an effective, evidence-based treatment for SUDs. Using the SMA model with elements of group therapy to provide OBOT allows physicians to spend more time with their patients, albeit in a group setting. SMA for OBOT will allow these physicians more time with high-risk patients. When done with elements of group therapy, SMAs can provide quality and cost-effective treatment. This manuscript will provide an overview of the scope of the current opioid problem, current treatment practices and barriers to treatment as well as guidelines on how to implement SMA model in an integrated care setting.
医疗访问包括多种医疗问题,几乎没有时间解决物质使用障碍问题,例如阿片类药物使用障碍的药物辅助治疗。这成为扩大基于办公室的阿片类药物治疗(OBOT)的障碍,因为许多医生对目前时间有限的治疗模式下治疗高风险患者表示担忧。有证据表明,共享医疗预约(SMAs)是一种有效的治疗模式,可以提高健康结果,并受到患者的欢迎。来自初级保健的研究表明,在初级保健中,大量的患者小组和有限的访问需要创造创新和有效的护理服务。物质使用障碍(sud)是与糖尿病和高血压相似的慢性疾病,治疗结果相似。团体治疗是一种有效的、以证据为基础的治疗sud的方法。使用SMA模型和团体治疗的元素来提供OBOT可以让医生花更多的时间和病人在一起,尽管是在团体环境中。针对OBOT的SMA将使这些医生有更多的时间与高危患者在一起。如果结合团体治疗的要素,sma可以提供高质量和具有成本效益的治疗。本文将概述当前阿片类药物问题的范围,当前的治疗实践和治疗障碍,以及如何在综合护理环境中实施SMA模型的指南。
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引用次数: 1
Synthesising Qualitative Research Methods (Observation and Participation) to Provide Deeper Understandings of Substance Use: A Commentary 综合定性研究方法(观察和参与)提供对物质使用的更深入理解:评论
Pub Date : 2017-05-18 DOI: 10.4172/2155-6105.1000327
Stephen Parkin
A central tenet of qualitative research is to gain an understanding of the social worlds of others and to unpack the concomitant livedexperiences of a particular phenomenon in order to develop an appreciation of the way in which people negotiate relational aspects of daily life [1]. Accordingly, for this reason, qualitative research has been frequently used as a way of informing and developing social policy and/or issues relating to health improvement [2]. The field of substance use and drug dependency typically intersects these fields of policy and health improvement. As such, there now exists a wealth of policyfocused, substance-use related literature that may be traced back to the Chicago School of urban sociology [3].
定性研究的一个核心原则是了解他人的社会世界,并解开特定现象的伴随生活经历,以便对人们在日常生活中协商关系方面的方式进行欣赏[1]。因此,由于这个原因,定性研究经常被用作告知和制定与健康改善有关的社会政策和/或问题的一种方式[2]。物质使用和药物依赖领域通常与这些政策和改善健康领域交叉。因此,现在存在大量以政策为中心的、与物质使用相关的文献,这些文献可以追溯到芝加哥城市社会学学派[3]。
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引用次数: 1
Coping with Young Self-Absorbed Group Members 应付以自我为中心的青少年小组成员
Pub Date : 2017-05-18 DOI: 10.4172/2155-6105.1000325
N. Brown
The previous study by Kearns and Brown used 200 volunteer participants attending a community AA program to determine what variables could distinguish between newcomers to the program, chronic relapsers and endurers. The discriminant analysis produced a factor that accounted for 80% of the variance with the group deviancy score on the GSQ loading at 0.69 and age as -0.84. This factor was termed “young and self-absorbed”. Presented here as a follow-up and guide for group leaders are the behavioral indicators and suggestions for coping with these behaviors to lessen their negative impact on the group, the members, the leader, and to prevent that member from being harmed in the group.
卡恩斯和布朗之前的研究使用了200名参加社区AA项目的志愿者,以确定哪些变量可以区分新加入项目的人、慢性复发者和持久者。判别分析产生了一个因子,该因子占方差的80%,GSQ负荷的组偏差评分为0.69,年龄为-0.84。这个因素被称为“年轻和自私”。这里提出的行为指标和应对这些行为的建议,作为小组领导的后续和指导,以减少他们对小组、成员、领导的负面影响,并防止该成员在小组中受到伤害。
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引用次数: 0
Structured Preparation before Alcohol Detoxification; A Shift from the Current Treatment Paradigm 酒精解毒前的结构准备;从当前治疗范式的转变
Pub Date : 2017-05-17 DOI: 10.4172/2155-6105.1000326
C. Kouimtsidis
The current treatment paradigm for alcohol dependence of planned medically assisted detoxification and aftercare has two main limitations; (i) only a percentage of people are engaged and exposed to aftercare, which is considered to be the effective treatment component; and (ii) does not take into account the accumulating evidence of the adverse effect of repeated medically assisted detoxifications. The proposed new treatment paradigm of Structured Preparation before Alcohol Detoxification (SPADe) is based on the most recent cognitive theories of addiction and aims to reverse the automatized decision making process, support lifestyle changes and conscious decision making, while amount of alcohol and pattern of drinking are kept stable, before proceeding to medically assisted detoxification. The current paper comments on the Abstinence Preparation Group, which is one of those interventions developed and evaluated following the SPADe paradigm.
目前的治疗模式酒精依赖计划的医疗辅助戒毒和护理有两个主要的局限性;(i)只有一定比例的人参与并接触到被认为是有效治疗组成部分的善后护理;而且(ii)没有考虑到不断积累的证据,证明反复进行医疗辅助戒毒会产生不利影响。提出的新治疗范式是基于最新的成瘾认知理论,旨在逆转自动化决策过程,支持生活方式的改变和有意识的决策,同时保持酒精量和饮酒模式稳定,然后进行医学辅助解毒。目前的论文评论禁欲准备组,这是一个干预开发和评估遵循SPADe范式。
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引用次数: 0
Delayed Posthypoxic Leucoencephalopaty: Is a Rare Condition in Patients after Episodes with Hypoxia Due to Drug Overdose with Opioids, Benzodiazepines and Barbiturates, Among Other Causes 迟发性后氧缺乏性白质脑病:在阿片类药物、苯二氮卓类药物和巴比妥类药物过量以及其他原因引起的缺氧发作后,是一种罕见的疾病
Pub Date : 2017-05-10 DOI: 10.4172/2155-6105.1000323
Moshgan Amiri, L. L. Larsen
Patients suffering from acute hypoxic episodes with respiratory failure and initial recovery, may in rare occasions present with neurological and neuropsychological symptoms occurring 2 to 4 weeks after recovery from the hypoxic episode. This rare entity is named Delayed Posthypoxic Leucoencephalopaty (DPHL). The patients present with typical MRI-findings of bilateral subcortical white matter lesions. The primary hypoxic episodes might, among other causes, be due to drug overdose with opioids, benzodiazepines and barbiturates. There is no evidence-based treatment for the condition and the majority of patients with DPHL recover spontaneously.
急性缺氧发作合并呼吸衰竭的患者在最初恢复时,在罕见情况下可能在缺氧发作恢复后2至4周出现神经和神经心理症状。这种罕见的疾病被命名为迟发性后氧性白质脑病(DPHL)。患者表现为典型的双侧皮质下白质病变。除其他原因外,原发性缺氧发作可能是由于过量使用阿片类药物、苯二氮卓类药物和巴比妥类药物。目前还没有针对这种疾病的循证治疗方法,大多数DPHL患者会自行康复。
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引用次数: 0
期刊
Journal of Addiction Research and Therapy
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