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Exploring Strategies for a Digital Tool to Support Medication Adherence Among Adolescents and Young Adults Undergoing Hematopoietic Stem Cell Transplant and Their Care Partners: Qualitative Formative Study. 探索在接受造血干细胞移植的青少年和年轻人及其护理伙伴中支持药物依从性的数字工具策略:定性形成研究。
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-17 DOI: 10.2196/82356
Gavin Raab, Zoe Bowen, Skyla Shea, Guy Shani, Michelle Rozwadowski, Susan Allbritton Murphy, Inbal Billie Nahum-Shani, Ziping Xu, Alexandra Psihogios, Sung Won Choi
<p><strong>Background: </strong>Allogeneic hematopoietic stem cell transplant (HCT) is a complex but essential treatment for malignant and nonmalignant conditions, requiring strict posttransplant adherence to immunosuppressant medications to prevent complications such as graft-versus-host disease. Adolescents and young adults undergoing HCT face unique challenges, including balancing growing independence with ongoing reliance on care partners, often parents. Medication adherence in this group is often suboptimal, and few interventions address adolescent and young adult-care partner dyads. To address this gap, we aim to develop a mobile health (mHealth) app that engages both the patients and care partner to improve adherence.</p><p><strong>Objective: </strong>As formative research for early-stage intervention development, this study aimed to (1) explore current HCT medication adherence strategies and challenges; (2) understand attitudes toward digital technology, including dyadic perspectives on app use to support adherence; and (3) assess adolescent and young adult-care partner relationships, including views on care partner involvement. This process was intended to inform the design of a relevant, user-centered mHealth app.</p><p><strong>Methods: </strong>Eligible participants included adolescents and young adult patients aged 12-39 years and primary care partners, such as parents, involved in medication management. Participants were recruited from a large academic medical center through direct outreach and electronic health records. Data collection involved 2 focus groups (6 dyads and 2 additional adolescents and young adults), 4 individual interviews (2 patients and 2 care partners), and 6 dyadic interviews. Semistructured sessions (in person or virtual) gathered feedback on medication adherence practices and app design preferences. All sessions were audio recorded with consent and professionally transcribed. Qualitative data were analyzed systematically: transcripts were deidentified, coded using both inductive and deductive strategies, and themes were refined through team consensus. Patterns were organized into major themes, and representative quotations were selected to illustrate findings. Data management was facilitated by NVivo (version 13; Lumivero) software.</p><p><strong>Results: </strong>We included 28 participants (15 adolescents and young adults and 13 care partners). The median age of adolescents and young adults was 18 (range 13-39) years and 53% (8/15) were female. Adolescents and young adults were 47% (7/15) White, 40% (6/15) Black, and 13% (2/15) mixed race. Care partners' median age was 48 (range 36-72) years, with 92% (12/13) female and 77% (10/13) White. Three principal themes emerged: (1) existing reminders and organizational tools are often insufficient for consistent adherence; (2) adherence barriers are multifaceted, often involving autonomy vs care partner support; and (3) both adolescents and young adults and care part
背景:同种异体造血干细胞移植(HCT)是一种复杂但必要的恶性和非恶性疾病治疗方法,需要在移植后严格遵守免疫抑制药物,以防止诸如移植物抗宿主病等并发症。接受HCT治疗的青少年和年轻人面临着独特的挑战,包括在日益增长的独立性与对护理伙伴(通常是父母)的持续依赖之间取得平衡。这一群体的药物依从性通常不是最佳的,很少有干预措施针对青少年和年轻成人的伴侣。为了解决这一差距,我们的目标是开发一个移动健康(mHealth)应用程序,让患者和护理伙伴都参与进来,以提高依从性。目的:作为早期干预发展的形成性研究,本研究旨在(1)探讨当前HCT药物依从性策略和挑战;(2)了解对数字技术的态度,包括对应用程序使用的二元观点,以支持依从性;(3)评估青少年和青年照顾伙伴关系,包括对照顾伙伴参与的看法。该过程旨在为相关的、以用户为中心的移动健康应用程序的设计提供信息。方法:符合条件的参与者包括12-39岁的青少年和年轻成人患者,以及参与药物管理的初级保健合作伙伴,如父母。参与者通过直接外联和电子健康记录从一家大型学术医疗中心招募。数据收集包括2个焦点小组(6对夫妇和另外2名青少年和年轻人),4个个人访谈(2名患者和2名护理伙伴)和6个二元访谈。半结构化的会议(面对面或虚拟)收集了关于药物依从性实践和应用程序设计偏好的反馈。所有会议均经同意录音,并由专业人员誊写。定性数据被系统地分析:转录本被去识别,使用归纳和演绎策略编码,并通过团队共识提炼主题。将模式组织成主要主题,并选择有代表性的引文来说明研究结果。数据管理由NVivo(版本13;Lumivero)软件实现。结果:我们纳入了28名参与者(15名青少年和年轻人以及13名护理伙伴)。青少年和青壮年的中位年龄为18岁(13-39岁),53%(8/15)为女性。青少年和年轻人中白人占47%(7/15),黑人占40%(6/15),混血儿占13%(2/15)。护理伙伴的年龄中位数为48岁(36-72岁),其中92%(12/13)为女性,77%(10/13)为白人。出现了三个主要主题:(1)现有的提醒和组织工具往往不足以保持一致的坚持;(2)依从性障碍是多方面的,通常涉及自主性与护理伙伴支持;(3)青少年和年轻人以及护理伙伴对二元数字健康干预表现出浓厚的兴趣,以促进协作和支持共同的依从性目标。结论:这项形成性研究强调了青少年和年轻成人护理伴侣双体中药物依从性的复杂动态,并支持双体移动健康应用程序的需求,以增强依从性、协作和关系质量。
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引用次数: 0
Accuracy of Optical Heart Rate Measurements for 10 Commercial Wearables in Different Climate Conditions and Activities: Instrument Validation Study. 10种商业可穿戴设备在不同气候条件和活动下光学心率测量的准确性:仪器验证研究。
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-17 DOI: 10.2196/85186
Jasper Gielen, Catharina Nina Van Oost, Glen Debard, Romy Sels, Nele A J De Witte, Toon Colman, Bert Bonroy, Jean-Marie Aerts

Background: Commercial wearable devices allow for continuous heart rate (HR) monitoring in daily life. Their accuracy under ecologically valid conditions, however, remains insufficiently independently tested, especially during irregular activity, cognitive stress, and variable climates.

Objective: This study evaluated the HR accuracy of 10 commercially available wearables under controlled variations in physical activity, cognitive stress, and temperature. We hypothesized that physical activity irregularity, cognitive stress, and thermal climate conditions would affect measurement accuracy.

Methods: Forty-five healthy adults (21-68, mean 34, SD 12 y) completed a standardized protocol in climate-controlled chambers simulating neutral (23 °C), hot (36 °C), and cold (10 °C) conditions. Tasks included rest, cognitive stress (Montreal Imaging Stress Task), steady walking, and intermittent walking. Each of the 10 devices (Fitbit Charge 6, Fitbit Inspire 3, Garmin Vivosmart 5, Garmin Vivoactive 5, Apple Watch SE, Google Pixel Watch 2, Polar Ignite 3, Polar Pacer, Xiaomi Watch 2, and Oura Ring Gen 3) was compared against electrocardiogram-derived HR from a Zephyr BioHarness chest strap. Accuracy was assessed using mean absolute error (MAE), mean absolute percentage error (MAPE), repeated-measures concordance correlation coefficient (CCC), and Bland-Altman analysis.

Results: Significant variability across the devices was observed. Fitbit Charge 6 (MAE 4.5 bpm, MAPE 5.5%, CCC 0.93) and Google Pixel Watch 2 (MAE 4.9 bpm, MAPE 6.7%, CCC 0.87) showed strong agreement with the gold standard. In contrast, Fitbit Inspire 3, Polar Ignite 3, Polar Pacer, and Oura Ring displayed larger errors (MAE 9-14 bpm, MAPE 11%-16%) and lower CCC values (0.45-0.66). The climate conditions did not significantly affect the measurement accuracy of the test devices. The activity type, however, did have a significant effect: intermittent walking increased errors for multiple devices.

Conclusions: Wearable HR measurement accuracy is device-specific and context-dependent. Moderate climates did not impair performance, but irregular movement reduced accuracy. Fitbit Charge 6 and Google Pixel Watch 2 demonstrated the highest reliability, supporting their use in health and sports monitoring. Careful device selection and context-aware interpretation remain critical for applied and clinical applications.

背景:商业可穿戴设备允许在日常生活中持续监测心率(HR)。然而,它们在生态有效条件下的准确性仍然没有得到充分的独立测试,特别是在不规律的活动、认知压力和多变的气候下。目的:本研究评估了10种市售可穿戴设备在控制体力活动、认知压力和温度变化下的HR准确性。我们假设身体活动不规律、认知压力和热气候条件会影响测量精度。方法:45名健康成人(21-68岁,平均34岁,标准差12岁)在模拟中性(23°C)、热(36°C)和冷(10°C)条件的气候控制室中完成标准化方案。任务包括休息、认知压力(蒙特利尔成像压力任务)、稳定行走和间歇性行走。10款设备(Fitbit Charge 6、Fitbit Inspire 3、Garmin Vivosmart 5、Garmin Vivoactive 5、Apple Watch SE、谷歌Pixel Watch 2、Polar Ignite 3、Polar Pacer、小米Watch 2和Oura Ring Gen 3)中的每一款都与Zephyr BioHarness胸带的心电图HR进行了比较。采用平均绝对误差(MAE)、平均绝对百分比误差(MAPE)、重复测量一致性相关系数(CCC)和Bland-Altman分析评估准确性。结果:观察到不同设备的显著差异。Fitbit Charge 6 (MAE 4.5 bpm, MAPE 5.5%, CCC 0.93)和谷歌Pixel Watch 2 (MAE 4.9 bpm, MAPE 6.7%, CCC 0.87)与黄金标准表现出强烈的一致性。相比之下,Fitbit Inspire 3、Polar Ignite 3、Polar Pacer和Oura Ring的误差较大(MAE 9- 14bpm, MAPE 11%-16%), CCC值较低(0.45-0.66)。气候条件对试验装置的测量精度影响不显著。然而,活动类型确实有显著的影响:间歇性行走增加了多种设备的错误。结论:可穿戴式人力资源测量精度与设备相关,与环境相关。温和的气候不会影响性能,但不规则的运动降低了准确性。Fitbit Charge 6和谷歌Pixel Watch 2表现出最高的可靠性,支持它们在健康和运动监测方面的应用。谨慎的设备选择和上下文感知解释仍然是应用和临床应用的关键。
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引用次数: 0
Exploring Proof of Concept for a Novel Web-Based Self-Management Support Intervention for Polycystic Ovary Syndrome: Multimethod Study. 探索一种新的基于网络的多囊卵巢综合征自我管理支持干预的概念证明:多方法研究。
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-17 DOI: 10.2196/69206
Carol Percy, Andy Turner, Bethan Alper, Petra A Wark
<p><strong>Background: </strong>Polycystic ovary syndrome (PCOS) is a common chronic hormonal condition affecting 8%-13% of women and individuals assigned female at birth. Symptoms may include subfertility, menstrual, skin, and metabolic problems, with long-term health risks including diabetes and cardiovascular disease. PCOS has a significant negative impact on mental health, quality of life, and well-being. We explored proof of concept for a web-based self-management support intervention, "Hope PCOS," designed to reduce anxiety and depression and increase positive well-being for women living with PCOS.</p><p><strong>Objective: </strong>We aim to pilot the intervention to test feasibility for web-based recruitment and delivery, acceptability, and potential to reduce anxiety and depression and increase positive well-being.</p><p><strong>Methods: </strong>Women with PCOS were recruited via social media with support from a patient advocacy charity and offered places on a 6-session cohort of the intervention. In a pre-post design, participants reported depression (Patient Health Questionnaire 9-Items), anxiety (Generalized Anxiety Disorder 7-Items), well-being (Warwick-Edinburgh Mental Wellbeing Scale), hope (SHS [State Hope Scale]), and gratitude (GQ-6 [Gratitude Questionnaire]) at baseline and 6 weeks. All participants who accessed 3 or more sessions were invited to a follow-up qualitative interview to explore user experience. Data from 8 interviews were thematically analyzed, and pre-post data were explored with descriptive statistics.</p><p><strong>Results: </strong>A total of 63 eligible women responded and were given access to the intervention. Three withdrew, leaving a baseline sample of 60, aged 20-58 (median 30, IQR 25-36) years. Further, 48 of the 60 started, of whom 46% (22/48) completed at least 3 sessions, and 29% (14/48) completed all 6. Additionally, 8 women (aged 25-38, median 29, IQR 26-35) years who completed between 3 and 6 sessions reported acceptability and experiences in exit interviews, including prioritizing self-care, developing a self-management mindset, setting motivating goals, improved mental health, self-compassion, reduced shame, openness about PCOS, preparedness for future health concerns, and continuing practice to consolidate behavior change. Furthermore, 11 women aged 25-43 (median 31, IQR 27-37) years, who completed 1-6 sessions (median 6, IQR 6-6), completed pre- and postintervention outcomes. Descriptive quantitative analysis indicated decreases in anxiety and depression and increases in hope agency, hope pathways, and gratitude. There was a meaningful (≥3 points) increase in well-being. Among patients with baseline and follow-up data, 73% (8/11) met clinical caseness for depression at baseline and 36% (4/11) post intervention.</p><p><strong>Conclusions: </strong>We explored proof of concept. Web-based recruitment and delivery online were feasible. We detected early signs of acceptability and potential benefits
背景:多囊卵巢综合征(PCOS)是一种常见的慢性激素疾病,影响8-13%的女性和出生时被指定为女性的个体。症状可能包括生育能力低下、月经、皮肤和代谢问题,具有长期健康风险,包括糖尿病和心血管疾病。多囊卵巢综合征对心理健康、生活质量和福祉有显著的负面影响。我们探索了基于网络的自我管理支持干预“希望多囊卵巢综合征”的概念证明,该干预旨在减少多囊卵巢综合征女性的焦虑和抑郁,并增加她们的积极幸福感。目的:试点干预措施,以测试网络招聘和交付的可行性,可接受性和潜力,以减少焦虑和抑郁,增加积极的幸福感。方法:在患者倡导慈善机构的支持下,通过社交媒体招募多囊卵巢综合征女性,并为其提供了六期干预队列的名额。在前-后设计中,参与者在基线和六周报告抑郁(PHQ-9)、焦虑(GAD-7)、幸福感(沃里克-爱丁堡心理健康量表(WEMWBS))、希望(状态希望量表(SHS))和感恩(感恩问卷(GQ-6))。所有参加了3次或以上会议的参与者都被邀请参加后续的定性访谈,以探讨用户体验。对8个访谈的数据进行主题分析,并对前后数据进行描述性统计。结果:63名符合条件的妇女回应并获得干预。3人退出,留下基线样本N=60,年龄20-58岁(中位数30岁)。60人中有48人开始,其中44%(22/48)完成了至少3个疗程,27%(14/48)完成了全部6个疗程。完成所有疗程的8名女性(年龄25-38岁,中位数29岁)报告了在离职面谈中的可接受性和经验,包括优先考虑自我保健、培养自我管理心态、设定激励目标、改善心理健康、自我同情、减少羞耻感、对多囊卵巢综合征持开放态度、为未来的健康问题做好准备,以及继续实践以巩固行为改变。11名年龄在25-43岁(中位31岁)的女性完成了1-6次治疗(中位6次),完成了干预前和干预后的结果。描述性定量分析表明,焦虑和抑郁有所减少,希望代理、希望途径和感激有所增加。他们的幸福感有显著提高(≥3分)。在基线和随访数据中,73%(8/11)的患者在基线时符合临床抑郁症病例,36%(4/11)的患者在干预后符合临床抑郁症病例。结论:我们探索了概念的证明。在线招聘和交付是可行的。我们发现了焦虑、抑郁和积极幸福感的早期可接受性和潜在益处,值得在对照试验中进行测试。未来的研究应评估随机对照试验的可行性,以评估有效性、可接受性和成本效益。临床试验:不适用,因为这是一个探索性的概念证明研究。
{"title":"Exploring Proof of Concept for a Novel Web-Based Self-Management Support Intervention for Polycystic Ovary Syndrome: Multimethod Study.","authors":"Carol Percy, Andy Turner, Bethan Alper, Petra A Wark","doi":"10.2196/69206","DOIUrl":"10.2196/69206","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Polycystic ovary syndrome (PCOS) is a common chronic hormonal condition affecting 8%-13% of women and individuals assigned female at birth. Symptoms may include subfertility, menstrual, skin, and metabolic problems, with long-term health risks including diabetes and cardiovascular disease. PCOS has a significant negative impact on mental health, quality of life, and well-being. We explored proof of concept for a web-based self-management support intervention, \"Hope PCOS,\" designed to reduce anxiety and depression and increase positive well-being for women living with PCOS.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;We aim to pilot the intervention to test feasibility for web-based recruitment and delivery, acceptability, and potential to reduce anxiety and depression and increase positive well-being.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Women with PCOS were recruited via social media with support from a patient advocacy charity and offered places on a 6-session cohort of the intervention. In a pre-post design, participants reported depression (Patient Health Questionnaire 9-Items), anxiety (Generalized Anxiety Disorder 7-Items), well-being (Warwick-Edinburgh Mental Wellbeing Scale), hope (SHS [State Hope Scale]), and gratitude (GQ-6 [Gratitude Questionnaire]) at baseline and 6 weeks. All participants who accessed 3 or more sessions were invited to a follow-up qualitative interview to explore user experience. Data from 8 interviews were thematically analyzed, and pre-post data were explored with descriptive statistics.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 63 eligible women responded and were given access to the intervention. Three withdrew, leaving a baseline sample of 60, aged 20-58 (median 30, IQR 25-36) years. Further, 48 of the 60 started, of whom 46% (22/48) completed at least 3 sessions, and 29% (14/48) completed all 6. Additionally, 8 women (aged 25-38, median 29, IQR 26-35) years who completed between 3 and 6 sessions reported acceptability and experiences in exit interviews, including prioritizing self-care, developing a self-management mindset, setting motivating goals, improved mental health, self-compassion, reduced shame, openness about PCOS, preparedness for future health concerns, and continuing practice to consolidate behavior change. Furthermore, 11 women aged 25-43 (median 31, IQR 27-37) years, who completed 1-6 sessions (median 6, IQR 6-6), completed pre- and postintervention outcomes. Descriptive quantitative analysis indicated decreases in anxiety and depression and increases in hope agency, hope pathways, and gratitude. There was a meaningful (≥3 points) increase in well-being. Among patients with baseline and follow-up data, 73% (8/11) met clinical caseness for depression at baseline and 36% (4/11) post intervention.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;We explored proof of concept. Web-based recruitment and delivery online were feasible. We detected early signs of acceptability and potential benefits ","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":" ","pages":"e69206"},"PeriodicalIF":2.0,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145300774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-World Use of a Mental Health AI Companion: Multiple Methods Study. 心理健康AI伴侣的真实世界使用:多种方法研究。
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-13 DOI: 10.2196/86904
Christine Callahan, Leah Tanner, Chelsea Coe, Michelle Davis, Jenna Glover, Ellis Bernstein, Katherine Scranton, Kenli Urruty, Matthew Chester, Sarah Kunkle
<p><strong>Background: </strong>The rapid acceleration of large language models (LLMs) creates opportunities to expand the accessibility of mental health support; however, general artificial intelligence (AI) tools lack safety guardrails, evidence-based practices, and medical regulation compliance, which may result in misinformation and failing to escalate care in crises. In contrast, Ebb, Headspace's conversational AI tool (CAI tool), was purpose-built by clinical psychologists and research experts using motivational interviewing techniques for subclinical guidance, incorporating clinically backed safety mechanisms.</p><p><strong>Objective: </strong>This study aimed to (1) understand Headspace members' sentiment toward AI and expectations for a mental health CAI tool, (2) evaluate real-world use of Headspace's CAI tool, and (3) understand how members perceive a CAI tool fitting into their mental health journey.</p><p><strong>Methods: </strong>This was a multiple method study using three data sources including Headspace members: (1) cross-sectional survey (n=482) assessing demographics, AI use, and the Artificial Intelligence Attitude Scale-4 (AIAS-4); (2) real-world engagement descriptive analysis (n=393,969) assessing session and message counts, retention, and conversation themes; and (3) diary study (n=15) exploring the CAI tool's role within members' mental health journey. App engagement was compared between CAI tool 1.0 and CAI tool 2.0, where CAI tool 2.0 featured enhanced LLM conversational prompts, comprehensive memory, woven content recommendations, and more robust safety detection.</p><p><strong>Results: </strong>While the majority of survey respondents used and would continue to use general AI tools, overall attitudes toward AI remained neutral (AIAS-4 mean 5.7, SD 2.2, range 1-10). Survey results suggest that members viewed the CAI tool as a guide to navigate to mental health resources and Headspace content and provide in-the-moment support. Members emphasized the need for data safety and ethics transparency, clinical guidelines structure, and for the CAI tool to be a resource in addition to human-delivered mental health care, not a replacement. Real-world CAI tool use showed strong engagement across 393,969 Headspace members. The product evolution to CAI tool 2.0 led to increased retention (77,894/153,249, 50.8% completed 2 sessions within 7 days vs 68,701/240,720, 28.5% for CAI tool 1.0) and higher positive conversation ratings (37,819/40,449, 93.5% vs 94,308/104,323, 90.4%). Retained CAI tool 2.0 users showed greater retention (6.1 sessions per user) compared to all CAI tool 2.0 users (2.9 sessions per user) and CAI tool 1.0 (2.4 sessions per user). Diary study results suggest that members imagined using the CAI tool when feeling stress or anxiety and during morning routines, commutes, or while winding down at night.</p><p><strong>Conclusions: </strong>Results emphasize the necessity of research-backed, purpose-built mental health
背景:大语言模型(LLMs)的快速加速为扩大心理健康支持的可及性创造了机会;然而,一般人工智能(AI)工具缺乏安全防护、循证实践和医疗法规合规性,这可能导致错误信息,无法在危机中升级护理。相比之下,Headspace的会话人工智能工具Ebb是由临床心理学家和研究专家专门开发的,使用动机性访谈技术进行亚临床指导,并结合临床支持的安全机制。目的:本研究旨在(1)了解Headspace会员对人工智能的看法和对心理健康CAI工具的期望,(2)评估Headspace CAI工具在现实生活中的使用情况,以及(3)了解会员如何看待CAI工具适合他们的心理健康旅程。方法:这是一项多方法研究,使用包括Headspace成员在内的三个数据源:(1)横断面调查(n=482)评估人口统计、人工智能使用和人工智能态度量表-4 (AIAS-4);(2)真实世界参与度描述性分析(n=393,969),评估会话和信息数量、留存率和对话主题;(3)日记研究(n=15)探索CAI工具在成员心理健康旅程中的作用。应用程序参与度比较了CAI工具1.0和CAI工具2.0,其中CAI工具2.0具有增强的LLM会话提示,全面记忆,编织内容推荐和更强大的安全检测。结果:虽然大多数受访者使用并将继续使用通用人工智能工具,但对人工智能的总体态度保持中立(AIAS-4平均5.7,SD 2.2,范围1-10)。调查结果表明,成员将CAI工具视为导航到心理健康资源和Headspace内容并提供即时支持的指南。成员们强调需要数据安全和伦理透明度、临床指南结构以及CAI工具作为人力提供的精神卫生保健之外的一种资源,而不是替代品。现实世界的CAI工具使用显示了393,969名Headspace成员的强烈参与。向CAI工具2.0的产品进化提高了留存率(77,894/153,249,50.8%在7天内完成了2次会话,而CAI工具1.0为68,701/240,720,28.5%)和更高的积极对话评分(37,819/40,449,93.5%,94,308/104,323,90.4%)。与所有CAI工具2.0用户(每个用户2.9次会话)和CAI工具1.0用户(每个用户2.4次会话)相比,保留CAI工具2.0用户显示出更高的保留率(每个用户6.1次会话)。日记研究结果表明,成员们在感到压力或焦虑、早晨例行工作、通勤或晚上放松时想象使用CAI工具。结论:结果强调了研究支持的、专门设计的心理健康人工智能产品的必要性,这些产品具有最低可行的保障措施,包括:(1)对预期用途、益处和局限性进行透明标注;(2)安全的设计原则,以监测过度使用,发现风险,并标志需要升级;(三)儿童青少年保障。
{"title":"Real-World Use of a Mental Health AI Companion: Multiple Methods Study.","authors":"Christine Callahan, Leah Tanner, Chelsea Coe, Michelle Davis, Jenna Glover, Ellis Bernstein, Katherine Scranton, Kenli Urruty, Matthew Chester, Sarah Kunkle","doi":"10.2196/86904","DOIUrl":"https://doi.org/10.2196/86904","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;The rapid acceleration of large language models (LLMs) creates opportunities to expand the accessibility of mental health support; however, general artificial intelligence (AI) tools lack safety guardrails, evidence-based practices, and medical regulation compliance, which may result in misinformation and failing to escalate care in crises. In contrast, Ebb, Headspace's conversational AI tool (CAI tool), was purpose-built by clinical psychologists and research experts using motivational interviewing techniques for subclinical guidance, incorporating clinically backed safety mechanisms.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to (1) understand Headspace members' sentiment toward AI and expectations for a mental health CAI tool, (2) evaluate real-world use of Headspace's CAI tool, and (3) understand how members perceive a CAI tool fitting into their mental health journey.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This was a multiple method study using three data sources including Headspace members: (1) cross-sectional survey (n=482) assessing demographics, AI use, and the Artificial Intelligence Attitude Scale-4 (AIAS-4); (2) real-world engagement descriptive analysis (n=393,969) assessing session and message counts, retention, and conversation themes; and (3) diary study (n=15) exploring the CAI tool's role within members' mental health journey. App engagement was compared between CAI tool 1.0 and CAI tool 2.0, where CAI tool 2.0 featured enhanced LLM conversational prompts, comprehensive memory, woven content recommendations, and more robust safety detection.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;While the majority of survey respondents used and would continue to use general AI tools, overall attitudes toward AI remained neutral (AIAS-4 mean 5.7, SD 2.2, range 1-10). Survey results suggest that members viewed the CAI tool as a guide to navigate to mental health resources and Headspace content and provide in-the-moment support. Members emphasized the need for data safety and ethics transparency, clinical guidelines structure, and for the CAI tool to be a resource in addition to human-delivered mental health care, not a replacement. Real-world CAI tool use showed strong engagement across 393,969 Headspace members. The product evolution to CAI tool 2.0 led to increased retention (77,894/153,249, 50.8% completed 2 sessions within 7 days vs 68,701/240,720, 28.5% for CAI tool 1.0) and higher positive conversation ratings (37,819/40,449, 93.5% vs 94,308/104,323, 90.4%). Retained CAI tool 2.0 users showed greater retention (6.1 sessions per user) compared to all CAI tool 2.0 users (2.9 sessions per user) and CAI tool 1.0 (2.4 sessions per user). Diary study results suggest that members imagined using the CAI tool when feeling stress or anxiety and during morning routines, commutes, or while winding down at night.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Results emphasize the necessity of research-backed, purpose-built mental health ","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":"10 ","pages":"e86904"},"PeriodicalIF":2.0,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146194699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Computerized Adaptive Test for the Knowledge of Effective Parenting Test-Internalizing Module: Instrument Validation Study. 有效育儿知识的计算机化自适应测验——内化模块:工具验证研究。
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-13 DOI: 10.2196/81646
Oliver Lindhiem, Hannah D Gallagher, Claire S Tomlinson, Rachel Vaughn-Coaxum, David J Kolko, Paul A Pilkonis, Lan Yu

Background: The development of efficient, scalable, and precise tools to assess knowledge of evidence-based parenting strategies is critical, particularly as increased parenting knowledge is a core target of many intervention programs.

Objective: This study aimed to develop and evaluate a computerized adaptive testing version of the Knowledge of Effective Parenting Test-Internalizing module (KEPT-I CAT).

Methods: Using computerized adaptive testing simulations from a large (n=1000) national dataset, we compared the performance of the KEPT-I CAT to both the full-length Knowledge of Effective Parenting Test-Internalizing module and a 10-item static short form (KEPT-I Brief).

Results: Results indicated that the KEPT-I CAT achieved comparable efficiency to the KEPT-I Brief (10 items), while demonstrating superior psychometric properties and modestly reducing the potential for practice effects.

Conclusions: Given these advantages, the KEPT-I CAT is well-suited for post-intervention assessment and may facilitate research examining how increases in parenting knowledge relate to changes in behavior and reductions in child internalizing symptoms.

背景:开发高效、可扩展和精确的工具来评估基于证据的育儿策略的知识是至关重要的,特别是因为增加育儿知识是许多干预计划的核心目标。目的:本研究旨在开发和评估有效育儿知识测试内化模块(keep - i CAT)的计算机自适应测试版本。方法:使用大型(n=1000)国家数据集的计算机自适应测试模拟,我们将keep -i CAT的表现与有效育儿知识测试的全长内部化模块和10项静态简短表格(keep -i Brief)进行比较。结果:结果表明,keep - i CAT与keep - i Brief(10项)的效率相当,同时表现出优越的心理测量特性,并适度降低了练习效果的潜力。结论:鉴于这些优势,keep -i CAT非常适合于干预后评估,并可能促进研究父母知识的增加与行为变化和儿童内化症状的减少之间的关系。
{"title":"A Computerized Adaptive Test for the Knowledge of Effective Parenting Test-Internalizing Module: Instrument Validation Study.","authors":"Oliver Lindhiem, Hannah D Gallagher, Claire S Tomlinson, Rachel Vaughn-Coaxum, David J Kolko, Paul A Pilkonis, Lan Yu","doi":"10.2196/81646","DOIUrl":"10.2196/81646","url":null,"abstract":"<p><strong>Background: </strong>The development of efficient, scalable, and precise tools to assess knowledge of evidence-based parenting strategies is critical, particularly as increased parenting knowledge is a core target of many intervention programs.</p><p><strong>Objective: </strong>This study aimed to develop and evaluate a computerized adaptive testing version of the Knowledge of Effective Parenting Test-Internalizing module (KEPT-I CAT).</p><p><strong>Methods: </strong>Using computerized adaptive testing simulations from a large (n=1000) national dataset, we compared the performance of the KEPT-I CAT to both the full-length Knowledge of Effective Parenting Test-Internalizing module and a 10-item static short form (KEPT-I Brief).</p><p><strong>Results: </strong>Results indicated that the KEPT-I CAT achieved comparable efficiency to the KEPT-I Brief (10 items), while demonstrating superior psychometric properties and modestly reducing the potential for practice effects.</p><p><strong>Conclusions: </strong>Given these advantages, the KEPT-I CAT is well-suited for post-intervention assessment and may facilitate research examining how increases in parenting knowledge relate to changes in behavior and reductions in child internalizing symptoms.</p>","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":"10 ","pages":"e81646"},"PeriodicalIF":2.0,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12904350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146194719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using Large Language Models to Summarize Evidence in Biomedical Articles: Exploratory Comparison Between AI- and Human-Annotated Bibliographies. 使用大型语言模型来总结生物医学文章中的证据:人工智能和人类注释书目的探索性比较。
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-12 DOI: 10.2196/69707
Michelle Colder Carras, Riaz Qureshi, Kevin Naaman, Faisal Aldayel, Mayank Date, Dahlia AlJuboori, Johannes Thrul
<p><strong>Background: </strong>Annotated bibliographies summarize literature, but training, experience, and time are needed to create concise yet accurate annotations. Summaries generated by artificial intelligence (AI) can save human resources, but AI-generated content can also contain serious errors.</p><p><strong>Objective: </strong>To determine the feasibility of using AI as an alternative to human annotators, we explored whether ChatGPT can generate annotations with characteristics that are comparable to those written by humans.</p><p><strong>Methods: </strong>We had 2 humans and 3 versions of ChatGPT (3.5, 4, and 5) independently write annotations on the same set of 15 publications. We collected data on word count and Flesch Reading Ease (FRE). In this study, 2 assessors who were masked to the source of the annotations independently evaluated (1) capture of main points, (2) presence of errors, and (3) whether the annotation included a discussion of both the quality and context of the article within the broader literature. We evaluated agreement and disagreement between the assessors and used descriptive statistics and assessor-stratified binary and cumulative mixed-effects logit models to compare annotations written by ChatGPT and humans.</p><p><strong>Results: </strong>On average, humans wrote shorter annotations (mean 90.20, SD 36.8 words) than ChatGPT (mean 113, SD 16 words) which were easier to interpret (human FRE score, mean 15.3, SD 12.4; ChatGPT FRE score, mean 5.76, SD 7.32). Our assessments of agreement and disagreement revealed that one assessor was consistently stricter than the other. However, assessor-stratified models of main points, errors, and quality/context showed similar qualitative conclusions. There was no statistically significant difference in the odds of presenting a better summary of main points between ChatGPT- and human-generated annotations for either assessor (Assessor 1: OR 0.96, 95% CI 0.12-7.71; Assessor 2: OR 1.64, 95% CI 0.67-4.06). However, both assessors observed that human annotations had lower odds of having one or more types of errors compared to ChatGPT (Assessor 1: OR 0.31, 95% CI 0.09-1.02; Assessor 2: OR 0.10, 95% CI 0.03-0.33). On the other hand, human annotations also had lower odds of summarizing the paper's quality and context when compared to ChatGPT (Assessor 1: OR 0.11, 95% CI 0.03-0.33; Assessor 2: OR 0.03, 95% CI 0.01-0.10). That said, ChatGPT's summaries of quality and context were sometimes inaccurate.</p><p><strong>Conclusions: </strong>Rapidly learning a body of scientific literature is a vital yet daunting task that may be made more efficient by AI tools. In our study, ChatGPT quickly generated concise summaries of academic literature and also provided quality and context more consistently than humans. However, ChatGPT's discussion of the quality and context was not always accurate, and ChatGPT annotations included more errors. Annotated bibliographies that are AI-generated and care
背景:注释书目总结了文献,但需要培训,经验和时间来创建简洁而准确的注释。人工智能(AI)生成的摘要可以节省人力资源,但AI生成的内容也可能包含严重的错误。目的:为了确定使用人工智能作为人类注释器的替代方案的可行性,我们探索了ChatGPT是否可以生成具有与人类编写的注释相当的特征的注释。方法:我们让2个人和3个版本的ChatGPT(3.5、4和5)在同一组15篇出版物上独立编写注释。我们收集了字数统计和Flesch Reading Ease (FRE)的数据。在这项研究中,两名被隐藏在注释来源的评估者独立评估了(1)对要点的捕捉,(2)错误的存在,以及(3)注释是否在更广泛的文献中包含了对文章质量和上下文的讨论。我们评估了评估者之间的一致和不一致,并使用描述性统计和评估者分层二元和累积混合效应logit模型来比较ChatGPT和人类编写的注释。结果:人类的注释平均较ChatGPT的注释短(平均90.20,SD 36.8单词)(平均113,SD 16单词),且更易于翻译(人类的FRE评分,平均15.3,SD 12.4; ChatGPT的FRE评分,平均5.76,SD 7.32)。我们对同意和不同意的评估表明,一个评估者始终比另一个更严格。然而,主要观点、误差和质量/背景的评估分层模型显示了类似的定性结论。对于任何一个评估者来说,ChatGPT和人工生成的注释更好地总结要点的几率没有统计学上的显著差异(评估者1:OR 0.96, 95% CI 0.12-7.71;评估者2:OR 1.64, 95% CI 0.67-4.06)。然而,两位评估者都观察到,与ChatGPT相比,人工注释具有一种或多种错误类型的几率更低(评估者1:or 0.31, 95% CI 0.09-1.02;评估者2:or 0.10, 95% CI 0.03-0.33)。另一方面,与ChatGPT相比,人工注释总结论文质量和上下文的几率也较低(评估者1:OR 0.11, 95% CI 0.03-0.33;评估者2:OR 0.03, 95% CI 0.01-0.10)。也就是说,ChatGPT对质量和上下文的总结有时是不准确的。结论:快速学习大量科学文献是一项重要而艰巨的任务,人工智能工具可能会提高效率。在我们的研究中,ChatGPT快速生成学术文献的简明摘要,并且比人类更一致地提供质量和上下文。然而,ChatGPT对质量和上下文的讨论并不总是准确的,而且ChatGPT注释包含了更多的错误。因此,人工智能生成并经过人类仔细验证的注释书目可能是提供文献快速概述的有效方法。需要更多的研究来确定提示工程在多大程度上可以减少错误并提高聊天机器人的性能。
{"title":"Using Large Language Models to Summarize Evidence in Biomedical Articles: Exploratory Comparison Between AI- and Human-Annotated Bibliographies.","authors":"Michelle Colder Carras, Riaz Qureshi, Kevin Naaman, Faisal Aldayel, Mayank Date, Dahlia AlJuboori, Johannes Thrul","doi":"10.2196/69707","DOIUrl":"10.2196/69707","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Annotated bibliographies summarize literature, but training, experience, and time are needed to create concise yet accurate annotations. Summaries generated by artificial intelligence (AI) can save human resources, but AI-generated content can also contain serious errors.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To determine the feasibility of using AI as an alternative to human annotators, we explored whether ChatGPT can generate annotations with characteristics that are comparable to those written by humans.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We had 2 humans and 3 versions of ChatGPT (3.5, 4, and 5) independently write annotations on the same set of 15 publications. We collected data on word count and Flesch Reading Ease (FRE). In this study, 2 assessors who were masked to the source of the annotations independently evaluated (1) capture of main points, (2) presence of errors, and (3) whether the annotation included a discussion of both the quality and context of the article within the broader literature. We evaluated agreement and disagreement between the assessors and used descriptive statistics and assessor-stratified binary and cumulative mixed-effects logit models to compare annotations written by ChatGPT and humans.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;On average, humans wrote shorter annotations (mean 90.20, SD 36.8 words) than ChatGPT (mean 113, SD 16 words) which were easier to interpret (human FRE score, mean 15.3, SD 12.4; ChatGPT FRE score, mean 5.76, SD 7.32). Our assessments of agreement and disagreement revealed that one assessor was consistently stricter than the other. However, assessor-stratified models of main points, errors, and quality/context showed similar qualitative conclusions. There was no statistically significant difference in the odds of presenting a better summary of main points between ChatGPT- and human-generated annotations for either assessor (Assessor 1: OR 0.96, 95% CI 0.12-7.71; Assessor 2: OR 1.64, 95% CI 0.67-4.06). However, both assessors observed that human annotations had lower odds of having one or more types of errors compared to ChatGPT (Assessor 1: OR 0.31, 95% CI 0.09-1.02; Assessor 2: OR 0.10, 95% CI 0.03-0.33). On the other hand, human annotations also had lower odds of summarizing the paper's quality and context when compared to ChatGPT (Assessor 1: OR 0.11, 95% CI 0.03-0.33; Assessor 2: OR 0.03, 95% CI 0.01-0.10). That said, ChatGPT's summaries of quality and context were sometimes inaccurate.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Rapidly learning a body of scientific literature is a vital yet daunting task that may be made more efficient by AI tools. In our study, ChatGPT quickly generated concise summaries of academic literature and also provided quality and context more consistently than humans. However, ChatGPT's discussion of the quality and context was not always accurate, and ChatGPT annotations included more errors. Annotated bibliographies that are AI-generated and care","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":"10 ","pages":"e69707"},"PeriodicalIF":2.0,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12900274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146179832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strengthening Nonspecialist Health Care Providers' Capacity to Address Mental Health in the Context of Domestic Violence in Nepal: Pre-Post Mixed Methods Training Evaluation. 加强非专业卫生保健提供者在尼泊尔家庭暴力背景下解决精神健康问题的能力:前后混合方法培训评估。
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-12 DOI: 10.2196/72793
Reena Koju, Rachana Shrestha, Jayanti Dhungana, Achyut Lamichhane, Diksha Sapkota, Anna Mia Ekström, Keshab Deuba

Background: Health care providers (HCPs) in public health facilities in low- and middle-income countries, including Nepal, often lack adequate training to manage mental health problems effectively.

Objective: This study evaluated the impact of structured mental health training on the knowledge, attitudes, confidence, and psychosocial support skills of nonspecialist HCPs in Madhesh Province, Nepal.

Methods: This study is a nested substudy within a larger domestic violence (DV) intervention trial and used a mixed method, pre-post intervention design with a comparison group. A total of 46 nonspecialist HCPs were randomized into 2 groups: group 1 (n=24) received a 10-day comprehensive mental health and violence prevention training; group 2 (n=22) received a 3-day training focused on ethical considerations, the link between intimate partner violence (IPV) or DV and mental health, and available referral services. The training was based on the World Health Organization's Problem Management Plus model, with augmented modules on safety planning and psychosocial support. Changes in knowledge and attitude scores were assessed at baseline, immediately post-training, and at 3-month follow-up. In-depth interviews with participants from group 1 were thematically analyzed.

Results: At baseline, nearly 90% of nonspecialist HCPs had not received any prior formal mental health training. Both groups demonstrated significant improvements in mental health knowledge, with a greater increase observed in group 1 (mean score 41.33-48.41) compared to group 2 (41.18-44.27). Attitudes toward individuals with mental health problems also improved in both groups, reflected in reductions in social distance and perceived dangerousness scores. Thematic analysis of interviews indicated enhanced confidence and psychosocial support skills, particularly in managing mental health concerns among women experiencing IPV or DV.

Conclusions: Structured mental health training significantly improved both knowledge and attitudes among nonspecialist HCPs in public health facilities in Madhesh Province. Participants also reported increased confidence in addressing common mental health concerns. This training model has potential for scale-up in other resource-limited settings to build frontline capacity in managing mental health problems and supporting women experiencing IPV or DV.

背景:包括尼泊尔在内的低收入和中等收入国家公共卫生设施中的卫生保健提供者往往缺乏有效管理精神卫生问题的适当培训。目的:本研究评估了结构化心理健康培训对尼泊尔马德什省非专业医护人员的知识、态度、信心和社会心理支持技能的影响。方法:本研究是一项大型家庭暴力(DV)干预试验的嵌套子研究,采用混合方法,干预前后设计与对照组。共有46名非专业医务人员被随机分为两组:第一组(n=24)接受为期10天的综合心理健康和暴力预防培训;第2组(n=22)接受了为期3天的培训,重点是道德考虑、亲密伴侣暴力(IPV)或家庭暴力与精神健康之间的联系,以及现有的转诊服务。培训以世界卫生组织的“问题管理+”模式为基础,增加了安全规划和社会心理支持模块。在基线、训练后立即和3个月随访时评估知识和态度得分的变化。对第一组参与者的深度访谈进行主题分析。结果:基线时,近90%的非专业HCPs没有接受过任何正式的心理健康培训。两组在心理健康知识方面均有显著改善,其中组1(平均得分41.33-48.41)比组2(平均得分41.18-44.27)有更大的提高。两组对有心理健康问题的人的态度也有所改善,这反映在社交距离和感知危险得分的减少上。对访谈进行的专题分析表明,信心和心理社会支持技能有所提高,特别是在处理遭受IPV或家庭暴力的妇女的心理健康问题方面。结论:有组织的心理健康培训显著改善了马德什省公共卫生机构非专业卫生专业人员的知识和态度。与会者还报告说,他们对解决常见心理健康问题的信心有所增强。这种培训模式有可能在其他资源有限的环境中扩大规模,以建立管理精神健康问题和支持遭受IPV或家庭暴力的妇女的一线能力。
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引用次数: 0
Community Participatory Co-Design and Development of a Digital Diabetes Prevention Education Program for Hispanic Families With Obesity: Mixed Methods Study. 西班牙裔肥胖家庭数字糖尿病预防教育项目的社区参与式共同设计和开发:混合方法研究。
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-11 DOI: 10.2196/67800
Sandra Mihail, Marbelly Partida, Lizette Villanueva, Debbe Thompson, Teresia M O'Connor, Salma M Musaad, Maria J Redondo, Erica G Soltero
<p><strong>Background: </strong>Digital health interventions (DHIs) can extend the reach of disease prevention interventions; however, few are evidence-based, theoretically grounded, or developed for high-risk youth and families. Co-design approaches engage end users in the design and development of the DHI, which can lead to increased accessibility and engagement.</p><p><strong>Objective: </strong>This study aimed to describe the adaptation of an evidence-based diabetes prevention program for remote, digital delivery.</p><p><strong>Methods: </strong>The adaptation of the in-person intervention was guided by a modified Inclusive Digital Health Intervention Design to Promote Health Equity framework and conducted in collaboration with Hispanic adolescents (n=23) with obesity (BMI ≥95th percentile) and their parents (n=15). Focus groups identified digital, health education, and support needs. An expert and community panel assisted in developing solutions based on these findings. A sample content session with a food tasting experience was created and reviewed by participants. The research team subsequently built a digital platform to host the content. Participants assessed the usability of the platform, including the ease of use, design components, and technical issues. A second meeting of the expert panel provided recommendations for further refinement and feedback.</p><p><strong>Results: </strong>Findings from focus groups indicated that most participants (31/36, 86.1%) reported stable internet access and multiple digital devices. With regard to format, a few parents (2/9, 22.2%) preferred synchronous content sessions, while most youth and parents favored asynchronous sessions (7/9, 77.8%) lasting 40 to 60 minutes. Health education needs included interactive content, healthy recipes, and the ability to ask questions. Experts suggested offering asynchronous sessions with monthly synchronous meetings to meet both parent and youth needs. After viewing a sample session, families found the content easy to understand and mostly engaging, with (17/21) 81% participating in the food tasting activity and all participants reporting that the activity was feasible. Experts recommended using a more conversational, interactive teaching style to improve the content and using a food box with nonperishable items to increase the ease of food tasting activities. While the digital platform was functional and easy to use, families highlighted the need for larger font and icon sizes, easier navigation, and better color contrasts. On the basis of this feedback, experts advised creating tutorial videos and an orientation session for platform training. The content and platform will continue to be refined before further evaluation in a 12-week feasibility pilot study.</p><p><strong>Conclusions: </strong>The use of a co-design approach provided opportunities to make content more interactive and engaging and to increase the ease of use of the digital platform. Describing the a
背景:数字卫生干预(DHIs)可以扩大疾病预防干预的范围;然而,很少有以证据为基础,理论为基础,或为高危青年和家庭开发的。协同设计方法让终端用户参与到DHI的设计和开发中,从而提高可访问性和参与度。目的:本研究旨在描述基于证据的糖尿病预防项目对远程数字化交付的适应性。方法:采用改进的包容性数字健康干预设计促进健康公平框架指导,并与肥胖(BMI≥95百分位)的西班牙裔青少年(n=23)及其父母(n=15)合作进行现场干预。焦点小组确定了数字、健康教育和支持需求。一个专家和社区小组协助根据这些调查结果制定解决办法。参与者创建了一个具有食物品尝体验的示例内容会话并对其进行了评论。研究小组随后建立了一个数字平台来托管这些内容。参与者评估了平台的可用性,包括易用性、设计组件和技术问题。专家小组第二次会议提出了进一步改进和反馈的建议。结果:焦点小组调查结果显示,大多数参与者(31/ 36,86.1%)报告了稳定的互联网接入和多个数字设备。在形式方面,少数家长(2/9,22.2%)更喜欢同步内容,而大多数青少年和家长更喜欢40 - 60分钟的异步内容(7/9,77.8%)。健康教育需求包括互动内容、健康食谱和提问能力。专家建议提供每月同步会议的非同步会议,以满足家长和青少年的需求。在观看了一个样本课程后,家庭发现内容简单易懂,大部分都很吸引人,(17/21)81%的家庭参加了品尝活动,所有参与者都表示活动是可行的。专家们建议采用更对话、互动的教学方式来改善内容,并使用装有不易腐烂物品的食品盒来增加食品品尝活动的便利性。虽然数字平台功能齐全且易于使用,但家庭强调需要更大的字体和图标尺寸,更容易的导航和更好的颜色对比。在此反馈的基础上,专家建议创建教程视频和平台培训的介绍会。内容和平台将继续完善,然后在为期12周的可行性试点研究中进行进一步评估。结论:协同设计方法的使用提供了使内容更具互动性和吸引力的机会,并增加了数字平台的易用性。与重点人群合作使用指导框架描述适应过程,将为旨在使循证干预措施适应数字平台的未来研究提供信息。
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引用次数: 0
Predictive Modeling of Preoperative Sleep Disorder Risk in Older Adults by Using Data From Wearable Monitoring Devices: Prospective Cohort Study. 利用可穿戴监测设备数据对老年人术前睡眠障碍风险进行预测建模:前瞻性队列研究
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-11 DOI: 10.2196/79008
Jingjing Li, Binxu Yang, Puzhong Gao, Dan Feng, Xinxin Shao, Xusihong Cai, Shuwen Huang, Yu Huang, Qingde Wa, Jing Zhou
<p><strong>Background: </strong>Sleep disorders are common among older adults undergoing surgery and contribute significantly to postoperative complications, delayed recovery, and higher health care costs. The combined effects of age-related physiological changes and surgical stress further disrupt sleep in this vulnerable group. However, current tools for predicting surgical risk rarely account for the specific physiological, clinical, and psychological factors that affect older patients. While wearable devices are used to monitor sleep, most prediction models focus on general sleep quality in nonsurgical populations, leaving a gap in forecasting preoperative sleep disorders in older surgical candidates. Therefore, we developed and validated a tailored risk prediction model that integrates objective sleep data from wearable devices with comprehensive clinical and psychosocial evaluations for older adults preparing for surgery.</p><p><strong>Objective: </strong>We aimed to develop and validate a risk prediction model for preoperative sleep disorders in older adult surgical patients by using data from smart wearable devices and clinical assessments, thereby facilitating early identification of the influencing factors and providing a scientific basis for personalized care planning.</p><p><strong>Methods: </strong>We conducted a prospective study at the Second Affiliated Hospital of Zunyi Medical University. A cohort of 242 older surgical patients was monitored using smart rings on the night before surgery. We simultaneously collected data on sociodemographic factors, cognition, and psychological status. As per preoperative sleep assessments, patients were classified into sleep disorder and non-sleep disorder groups. Independent predictors of sleep disorders were identified using univariable and multivariable logistic regression. These predictors were used to build a risk prediction model, which was internally validated with 1000 bootstrap samples. The model's performance was evaluated by its ability to discriminate between groups (using receiver operating characteristic curves), its calibration, and its clinical usefulness (via decision curve analysis).</p><p><strong>Results: </strong>Multifactorial logistic regression analysis showed that Hospital Anxiety and Depression Scale score (odds ratio [OR] 3.21, 95% CI 1.54-6.69; P=.002), number of awakenings (OR 3.33, 95% CI 1.82-6.12; P<.001), duration of rapid eye movement sleep (OR 0.96, 95% CI 0.93-0.99; P=.04), and duration of light sleep (OR 0.98, 95% CI 0.96-0.99; P=.01) were independent risk factors for preoperative sleep disturbances in older adults (P<.05). The receiver operating characteristic curve showed an area under the curve of 0.92, and the calibration curve indicated good model calibration. Decision curve analysis showed that the model improved the maximum net benefit across risk thresholds ranging from 0.2 to 0.8, indicating high clinical utility.</p><p><strong>Conclusions: </strong>Th
背景:睡眠障碍在接受手术的老年人中很常见,并且是术后并发症、延迟恢复和更高医疗费用的重要因素。年龄相关的生理变化和手术压力的综合影响进一步扰乱了这一弱势群体的睡眠。然而,目前预测手术风险的工具很少考虑到影响老年患者的特定生理、临床和心理因素。虽然可穿戴设备用于监测睡眠,但大多数预测模型关注的是非手术人群的一般睡眠质量,这在预测老年手术患者的术前睡眠障碍方面留下了空白。因此,我们开发并验证了一个定制的风险预测模型,该模型将来自可穿戴设备的客观睡眠数据与准备手术的老年人的综合临床和心理社会评估相结合。目的:利用智能可穿戴设备数据和临床评估数据,建立并验证老年外科患者术前睡眠障碍风险预测模型,以便及早发现影响因素,为个性化护理规划提供科学依据。方法:在遵义医科大学第二附属医院进行前瞻性研究。242名老年手术患者在手术前使用智能环进行监测。我们同时收集了社会人口因素、认知和心理状态的数据。根据术前睡眠评估,将患者分为睡眠障碍组和非睡眠障碍组。使用单变量和多变量逻辑回归确定睡眠障碍的独立预测因子。使用这些预测因子构建风险预测模型,并使用1000个bootstrap样本进行内部验证。该模型的性能通过其组间区分能力(使用受试者工作特征曲线)、校准能力和临床实用性(通过决策曲线分析)来评估。结果:多因素logistic回归分析显示,医院焦虑与抑郁量表评分(比值比[OR] 3.21, 95% CI 1.54-6.69; P= 0.002)、醒来次数(OR 3.33, 95% CI 1.82-6.12; P)、睡眠障碍风险预测模型有效识别高龄手术患者术前睡眠障碍风险升高,有助于及时、个体化干预。这一进展为提供个性化围手术期护理提供了坚实的科学基础,具有改善术后预后和减轻弱势人群医疗负担的潜力。
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引用次数: 0
Physician Perspectives on Web-Based Real-World Statistics for Better-Informed Drug Selection in Epilepsy: Mixed Methods Study. 医生对基于网络的真实世界统计数据的观点,以更好地了解癫痫药物选择:混合方法研究。
IF 2 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2026-02-11 DOI: 10.2196/82958
David Larsson, André Idegård, Samuel Håkansson, Johan Zelano

Background: Lately, big data studies have shown promise in using patient characteristics to rank the likelihood of retention of antiseizure medications (ASMs), a measure indicating tolerability as well as effect. How such results can be integrated into clinical practice has yet to be studied. We developed EPstat, a noncommercial tool that provides physicians with real-world treatment retention data from 33,998 patients with epilepsy.

Objective: This study investigated the user experience of EPstat after its pilot launch.

Methods: EPstat was developed in an iterative process with first a prototype and then a final version accessible on the health care region intranet. EPstat was launched in 2022 through emails and information meetings at neurology departments. After 1 year, an online questionnaire was distributed to physicians in our health service region's neurology clinics (5 hospitals). Descriptive statistics and thematic analysis were used to summarize responses. To supplement the survey, 3 semistructured workshops or group interviews with neurologists and residents were used to gather further feedback.

Results: Of the 27 survey respondents, 19 (70%) were aware of EPstat and 10 (37%) had used it. Users rated EPstat highly for ease of use (median 5, IQR 4-5) and applicability in clinical practice (median 4, IQR 4-4). Two of the 10 respondents who had used it indicated that the platform had influenced their choice of ASM. Workshop participants advocated for expanding the platform to include retention data on newer ASMs and general information relevant to epilepsy management.

Conclusions: The notion of using big data to improve ASM selection was well received. However, there were barriers to the initial use, and users requested a more comprehensive resource that also incorporated other information related to epilepsy. EPstat is now being updated with more recent ASM statistics, including information on newer ASMs. Mobile access, more information for physicians, and mentioning the tool in regional guidelines are some possible measures to increase use. Linking multinational statistics could also increase the precision of the presented data and, thus, increase usefulness. Study of EPstat will continue and should include thematic analysis of representative and rigorously sampled workshop participants. Such studies are also likely to provide information on how physicians and health services receive web-based tools, which are likely to soon be driven by artificial intelligence. In similar projects, we recommend greater participatory involvement of both health care providers and patients already at the design stage.

背景:最近,大数据研究显示了利用患者特征对抗癫痫药物(asm)保留可能性进行排序的希望,这是一种表明耐受性和效果的措施。如何将这些结果整合到临床实践中还有待研究。我们开发了EPstat,这是一个非商业工具,为医生提供来自33,998例癫痫患者的真实治疗保留数据。目的:研究EPstat试用后的用户体验。方法:EPstat是在一个迭代过程中开发的,首先是一个原型,然后是一个最终版本,可在卫生保健区域内联网上访问。EPstat于2022年通过电子邮件和神经病学部门的信息会议启动。1年后,向本卫生服务区(5家医院)神经内科门诊医师发放在线问卷。使用描述性统计和专题分析来总结回应。作为调查的补充,我们对神经科医生和住院医师进行了3次半结构化研讨会或小组访谈,以收集进一步的反馈。结果:27名被调查者中,19名(70%)知道EPstat, 10名(37%)使用过EPstat。用户对EPstat的易用性(中位数5,IQR 4-5)和临床实践的适用性(中位数4,IQR 4-4)评价很高。在10个使用过该平台的受访者中,有两个表示该平台影响了他们对ASM的选择。讲习班与会者主张扩大该平台,使其包括有关较新的asm的保留数据和与癫痫管理有关的一般信息。结论:利用大数据改进ASM选择的概念得到了广泛认可。然而,最初的使用存在障碍,用户要求获得更全面的资源,其中也包括与癫痫有关的其他信息。EPstat现在正在更新ASM的最新统计数据,包括新ASM的信息。移动访问、为医生提供更多信息以及在区域指南中提及该工具是增加使用的一些可能措施。将多国统计数据联系起来也可以提高所提供数据的准确性,从而增加有用性。对EPstat的研究将继续进行,并应包括对有代表性和严格抽样的讲习班参加者的专题分析。此类研究还可能提供有关医生和卫生服务如何接受基于网络的工具的信息,这些工具可能很快就会由人工智能驱动。在类似的项目中,我们建议已经在设计阶段的卫生保健提供者和患者加强参与。
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引用次数: 0
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