Sara Mijares St George, Blanca S Noriega Esquives, Rafael Leite, Vanina Pavia Aubry, Rana Saber, Yaray Agosto, Marissa Kobayashi, Guillermo Prado
Background: Hispanic youth in the United States have the highest rates of pediatric obesity and do not often meet national guidelines for physical activity and dietary intake. Family-based interventions can improve health outcomes in both youth and their parents and are highly relevant to Hispanics due to the cultural value of familismo (familism). However, few existing family-based obesity prevention interventions for Hispanics target adolescents and their parents, and those that do are not designed to facilitate widespread reach.
Objective: This study describes the development of Healthy Juntos (Healthy Together), a family-based intervention for Hispanic adolescents and their parents that leverages the web and smartphone technology to prevent the onset of adolescent obesity by promoting healthy lifestyle behaviors (physical activity and diet).
Methods: We used an iterative co-design process guided by the Integrate, Design, Assess, and Share (IDEAS) framework, which outlines 10 phases for developing digital interventions. Hispanic adolescents at risk for obesity and their parents (n=90; 45 dyads) participated across different phases of the intervention development process. We conducted qualitative interviews to understand their needs and preferences and to gather feedback on a series of intervention prototypes (conceptual, paper and minimally functional, and fully functional).
Results: Participants reported using technology for their health in limited ways (eg, to search for medical symptoms and recipes). They described the importance of having interactive and social features as part of a family-based digital health intervention. Their suggestions related to content, functionality, and aesthetics resulted in a fully functional prototype of a digital lifestyle intervention for Hispanic adolescents and their parents.
Conclusions: The iterative co-design process was crucial for refining the Healthy Juntos intervention. Our next steps are to evaluate its feasibility, acceptability, and preliminary effects through a pilot randomized controlled trial.
{"title":"Family-Based Digital Lifestyle Intervention for Hispanic Adolescents and Their Parents: Iterative Co-Design and Development Study.","authors":"Sara Mijares St George, Blanca S Noriega Esquives, Rafael Leite, Vanina Pavia Aubry, Rana Saber, Yaray Agosto, Marissa Kobayashi, Guillermo Prado","doi":"10.2196/73848","DOIUrl":"10.2196/73848","url":null,"abstract":"<p><strong>Background: </strong>Hispanic youth in the United States have the highest rates of pediatric obesity and do not often meet national guidelines for physical activity and dietary intake. Family-based interventions can improve health outcomes in both youth and their parents and are highly relevant to Hispanics due to the cultural value of familismo (familism). However, few existing family-based obesity prevention interventions for Hispanics target adolescents and their parents, and those that do are not designed to facilitate widespread reach.</p><p><strong>Objective: </strong>This study describes the development of Healthy Juntos (Healthy Together), a family-based intervention for Hispanic adolescents and their parents that leverages the web and smartphone technology to prevent the onset of adolescent obesity by promoting healthy lifestyle behaviors (physical activity and diet).</p><p><strong>Methods: </strong>We used an iterative co-design process guided by the Integrate, Design, Assess, and Share (IDEAS) framework, which outlines 10 phases for developing digital interventions. Hispanic adolescents at risk for obesity and their parents (n=90; 45 dyads) participated across different phases of the intervention development process. We conducted qualitative interviews to understand their needs and preferences and to gather feedback on a series of intervention prototypes (conceptual, paper and minimally functional, and fully functional).</p><p><strong>Results: </strong>Participants reported using technology for their health in limited ways (eg, to search for medical symptoms and recipes). They described the importance of having interactive and social features as part of a family-based digital health intervention. Their suggestions related to content, functionality, and aesthetics resulted in a fully functional prototype of a digital lifestyle intervention for Hispanic adolescents and their parents.</p><p><strong>Conclusions: </strong>The iterative co-design process was crucial for refining the Healthy Juntos intervention. Our next steps are to evaluate its feasibility, acceptability, and preliminary effects through a pilot randomized controlled trial.</p>","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":"10 ","pages":"e73848"},"PeriodicalIF":2.0,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12875426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nora Yanyi Sun, Sofia Eun-Young Guerra, Mahie Mangesh Patil, Sai Supritha Chakravadhanula, Christopher Pittenger, Terence Ching
Unlabelled: To elucidate the complex relationship between spirituality and obsessive-compulsive disorder (OCD), we performed a qualitative analysis of messages (n=225) referencing spiritualities in r/OCD, a public online peer support forum for people with OCD with over 250,000 users; two central themes emerged: (1) influence of spirituality on OCD symptom manifestation and (2) impact of OCD on relationship with spirituality.
{"title":"Characterizing the Multidimensional Relationship Between Spirituality and Obsessive-Compulsive Disorder: Thematic Analysis.","authors":"Nora Yanyi Sun, Sofia Eun-Young Guerra, Mahie Mangesh Patil, Sai Supritha Chakravadhanula, Christopher Pittenger, Terence Ching","doi":"10.2196/81964","DOIUrl":"10.2196/81964","url":null,"abstract":"<p><strong>Unlabelled: </strong>To elucidate the complex relationship between spirituality and obsessive-compulsive disorder (OCD), we performed a qualitative analysis of messages (n=225) referencing spiritualities in r/OCD, a public online peer support forum for people with OCD with over 250,000 users; two central themes emerged: (1) influence of spirituality on OCD symptom manifestation and (2) impact of OCD on relationship with spirituality.</p>","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":"10 ","pages":"e81964"},"PeriodicalIF":2.0,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12875421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146124999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria C Latimer, Lydia Gregg, Mustapha Saheed, Karin E Tobin, Sharon M Kelly, Tracy Agee, R Joshua Steele, Nicholas Frankiewicz, Tarfa Verinumbe, Carl Latkin, Oluwaseun Falade-Nwulia
<p><strong>Background: </strong>The ongoing opioid epidemic has been associated with increases in emergency department visits and hospitalizations for drug overdose and injection-related infections. These encounters with the health care system provide an opportunity to offer drug treatment linkage and support for people with opioid use disorder (OUD). There is a need for interventions that enhance linkage to and engagement in treatment with medication for opioid use disorder (MOUD) for people with OUD identified in hospital settings as they transition back to community settings.</p><p><strong>Objective: </strong>The mTools4life (Johns Hopkins University) study aimed to develop and evaluate a peer-led intervention integrating narrative-based health communication into a mobile health (mHealth) app to increase posthospitalization engagement in MOUD and reduce substance use.</p><p><strong>Methods: </strong>The formative phase of the study consisted of semistructured interviews with people with OUD and clinicians who provide care to people with OUD. Interviews sought to identify salient content to include in visual narratives within the mHealth app and information that may increase motivations for behavior change related to MOUD engagement. The intervention was developed in accordance with the information-motivation-behavioral skills model, transportation theory, and the transtheoretical model. The pilot phase of mTools4Life (Johns Hopkins University) aimed to evaluate the acceptability and usability of the intervention. People with OUD were recruited from the Johns Hopkins Hospital Emergency Department and consented to receive the intervention for a 3-month period. Participants completed a study survey at baseline and a 3-month follow-up. Data on demographics, past 30-day substance use, MOUD, and intervention appropriateness and acceptability were obtained at both time points. Additional data on intervention uptake and frequency of use were collected at follow-up. Dependent samples 2-tailed t tests were conducted on continuous data, and Fisher exact tests were conducted on count data.</p><p><strong>Results: </strong>Twenty people with OUD piloted the intervention. The sample was mostly male (13/20, 65%) and non-Hispanic White (13/20, 65%) with a mean age of 41.1 (SD 8.7) years. Most participants (16/20, 80%) completed the 3-month follow-up. Fewer participants reported opioid use at follow-up (9/16, 56.3%) compared to baseline (20/20, 100%; P=.001, and mean days of opioid use out of the past 30 days declined from baseline (19.9, SD 11.7) to follow-up (8.3, SD 11.4; P=.002). MOUD treatment in the prior 3 months was reported by 65% (13/20) of participants at baseline and 81.3% (13/16) at follow-up (P=.46). Most participants used the app (11/16, 68.8%) or engaged with their peer navigator (10/16, 62.5%) during the intervention period. At follow-up, mean acceptability and appropriateness scores (scale 0-5; higher score indicating greater acceptability or
{"title":"A Peer-Led, Narrative-Based, and Mobile-Supported Intervention in Opioid Use Disorder: Multiphase Qualitative and Longitudinal Observational Study.","authors":"Maria C Latimer, Lydia Gregg, Mustapha Saheed, Karin E Tobin, Sharon M Kelly, Tracy Agee, R Joshua Steele, Nicholas Frankiewicz, Tarfa Verinumbe, Carl Latkin, Oluwaseun Falade-Nwulia","doi":"10.2196/82485","DOIUrl":"10.2196/82485","url":null,"abstract":"<p><strong>Background: </strong>The ongoing opioid epidemic has been associated with increases in emergency department visits and hospitalizations for drug overdose and injection-related infections. These encounters with the health care system provide an opportunity to offer drug treatment linkage and support for people with opioid use disorder (OUD). There is a need for interventions that enhance linkage to and engagement in treatment with medication for opioid use disorder (MOUD) for people with OUD identified in hospital settings as they transition back to community settings.</p><p><strong>Objective: </strong>The mTools4life (Johns Hopkins University) study aimed to develop and evaluate a peer-led intervention integrating narrative-based health communication into a mobile health (mHealth) app to increase posthospitalization engagement in MOUD and reduce substance use.</p><p><strong>Methods: </strong>The formative phase of the study consisted of semistructured interviews with people with OUD and clinicians who provide care to people with OUD. Interviews sought to identify salient content to include in visual narratives within the mHealth app and information that may increase motivations for behavior change related to MOUD engagement. The intervention was developed in accordance with the information-motivation-behavioral skills model, transportation theory, and the transtheoretical model. The pilot phase of mTools4Life (Johns Hopkins University) aimed to evaluate the acceptability and usability of the intervention. People with OUD were recruited from the Johns Hopkins Hospital Emergency Department and consented to receive the intervention for a 3-month period. Participants completed a study survey at baseline and a 3-month follow-up. Data on demographics, past 30-day substance use, MOUD, and intervention appropriateness and acceptability were obtained at both time points. Additional data on intervention uptake and frequency of use were collected at follow-up. Dependent samples 2-tailed t tests were conducted on continuous data, and Fisher exact tests were conducted on count data.</p><p><strong>Results: </strong>Twenty people with OUD piloted the intervention. The sample was mostly male (13/20, 65%) and non-Hispanic White (13/20, 65%) with a mean age of 41.1 (SD 8.7) years. Most participants (16/20, 80%) completed the 3-month follow-up. Fewer participants reported opioid use at follow-up (9/16, 56.3%) compared to baseline (20/20, 100%; P=.001, and mean days of opioid use out of the past 30 days declined from baseline (19.9, SD 11.7) to follow-up (8.3, SD 11.4; P=.002). MOUD treatment in the prior 3 months was reported by 65% (13/20) of participants at baseline and 81.3% (13/16) at follow-up (P=.46). Most participants used the app (11/16, 68.8%) or engaged with their peer navigator (10/16, 62.5%) during the intervention period. At follow-up, mean acceptability and appropriateness scores (scale 0-5; higher score indicating greater acceptability or ","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":"10 ","pages":"e82485"},"PeriodicalIF":2.0,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12875427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Mobile (m)health interventions can expand access to and engagement in lifesaving treatment for pregnant and postpartum people with a substance use disorder (SUD). Yet, many people with lived experience and substance use providers alike are often excluded from mobile health intervention development, limiting opportunities to provide feedback on critical design components such as usability, cultural relevance, and compatibility with real-world practice.
Objective: The study engaged pregnant and postpartum people and substance use providers in formative evaluation to refine a mobile health intervention designed to support recovery.
Methods: Pregnant and postpartum participants (n=11) and providers working in recovery settings (n=13) across Missouri reviewed the same mHealth intervention. Participants completed survey and semi-structured qualitative questions on usability and compatibility after reviewing the same mHealth intervention. Survey responses and qualitative themes were compared across groups. Post hoc analyses examined differences between pregnant and postpartum participants who had used the app and those who had not (n=8) to identify barriers to participation.
Results: Both participant groups reported similar themes related to the usability and compatibility of the mobile health intervention, including a need for simplified navigation and greater personalization of app content. The e-coaching feature and directory of recovery-focused resources were viewed as valuable by both groups. Uniquely, pregnant and postpartum participants emphasized the need for app content addressing craving management, emotional triggers, and parenting stress. These participants also requested more frequent communication with the e-coach than providers recommended. Non-app users differed from app users by race, education, and household characteristics, underscoring structural barriers to engagement.
Conclusions: Engaging both pregnant and postpartum people and providers in formative evaluation reveals overlapping and distinct priorities for mHealth design. Findings highlight that user-informed development is essential for improving usability, engagement, and recovery outcomes, including reaching those least likely to engage with traditional or digital treatment supports.
{"title":"Comparing pregnant and postpartum client and provider feedback on a digital health intervention for substance use recovery: A qualitative study.","authors":"Hannah Szlyk, Layna Paraboschi, Lucy Meigs, Elecia Worley, JaNiene Peoples, Emily Maranets, Erin Kasson, Alex T Ramsey, Corey Lau, Kristin Korte, Patricia Cavazos-Rehg","doi":"10.2196/86255","DOIUrl":"https://doi.org/10.2196/86255","url":null,"abstract":"<p><strong>Background: </strong>Mobile (m)health interventions can expand access to and engagement in lifesaving treatment for pregnant and postpartum people with a substance use disorder (SUD). Yet, many people with lived experience and substance use providers alike are often excluded from mobile health intervention development, limiting opportunities to provide feedback on critical design components such as usability, cultural relevance, and compatibility with real-world practice.</p><p><strong>Objective: </strong>The study engaged pregnant and postpartum people and substance use providers in formative evaluation to refine a mobile health intervention designed to support recovery.</p><p><strong>Methods: </strong>Pregnant and postpartum participants (n=11) and providers working in recovery settings (n=13) across Missouri reviewed the same mHealth intervention. Participants completed survey and semi-structured qualitative questions on usability and compatibility after reviewing the same mHealth intervention. Survey responses and qualitative themes were compared across groups. Post hoc analyses examined differences between pregnant and postpartum participants who had used the app and those who had not (n=8) to identify barriers to participation.</p><p><strong>Results: </strong>Both participant groups reported similar themes related to the usability and compatibility of the mobile health intervention, including a need for simplified navigation and greater personalization of app content. The e-coaching feature and directory of recovery-focused resources were viewed as valuable by both groups. Uniquely, pregnant and postpartum participants emphasized the need for app content addressing craving management, emotional triggers, and parenting stress. These participants also requested more frequent communication with the e-coach than providers recommended. Non-app users differed from app users by race, education, and household characteristics, underscoring structural barriers to engagement.</p><p><strong>Conclusions: </strong>Engaging both pregnant and postpartum people and providers in formative evaluation reveals overlapping and distinct priorities for mHealth design. Findings highlight that user-informed development is essential for improving usability, engagement, and recovery outcomes, including reaching those least likely to engage with traditional or digital treatment supports.</p><p><strong>Clinicaltrial: </strong></p>","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146165423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kim Sarah Sczuka, Marc Schneider, Ngaire Kerse, Clemens Becker, Jochen Klenk
<p><strong>Background: </strong>Falls are a leading cause of injury among older adults, often resulting from dynamic balance disturbances. It is influenced by a complex interplay of intrinsic and extrinsic fall-risk factors. To identify individual fall risks, it is important to understand the underlying associations.</p><p><strong>Objective: </strong>This study aimed to build an experimental setup modeling selected factors leading to a loss of balance, measured by the margin of stability (MoS) in an ecologically valid real-world example (tripping). Additionally, these analyses aimed to assess the feasibility and safety of the protocol and to explore the use of the MoS as part of a prototypical dynamic fall-risk model to differentiate between fall-risk groups.</p><p><strong>Methods: </strong>Nineteen community-dwelling older adults (mean age of 71, SD 3.67 y; n=7, 37% women) completed the tripping protocol involving perturbations under various conditions. Clinical assessments were used to identify relevant fall-related intrinsic fall-risk factors. MoS was measured using an 8-camera motion capture system. Receiver operating characteristic analyses determined the ability of MoS to distinguish between low and high fall-risk groups.</p><p><strong>Results: </strong>Approximately one-quarter of participants discontinued before or at the start of the tripping scenario because of discomfort or fear of perturbations, indicating that perceived safety is an important feasibility factor. Perturbations significantly disrupted MoS, with a median MoS of -106.05 (IQR -181.40 to -41.50) mm during the perturbed step compared to 114 (IQR 81.20-155.20) mm in the preperturbation step. Recovery steps showed progressive stabilization, with the second recovery step achieving a median MoS of 88.45 (IQR 47.50-137.80) mm. The second recovery step exhibited the highest predictive accuracy for fall-risk differentiation, with area under the curve values reaching 82.3% during slow walking with a series of right-sided perturbations. In contrast, fast walking with random perturbations yielded lower area under the curve values (64.9%). Slow walking conditions generally demonstrated the clearest separation between fall-risk groups.</p><p><strong>Conclusions: </strong>This pilot and feasibility study demonstrates the applicability of a tripping paradigm to perturb MoS in older adults and provides preliminary insights into its association with fall-risk indices. While the protocol proved safe and feasible for fit older adults, perceived safety limited full participation. The findings are exploratory and intended to guide the design of larger prospective studies rather than to establish predictive conclusions. These data suggest that MoS during controlled tripping may help differentiate fall-risk strata, but confirmation will require adequately powered studies in more diverse and frailer older populations-and across multiple real-world scenarios-before any clinical implementation can
{"title":"Association of Fall-Risk Factors and Margin of Stability While Tripping in Community-Dwelling Older Adults: Experimental Pilot Study.","authors":"Kim Sarah Sczuka, Marc Schneider, Ngaire Kerse, Clemens Becker, Jochen Klenk","doi":"10.2196/74418","DOIUrl":"10.2196/74418","url":null,"abstract":"<p><strong>Background: </strong>Falls are a leading cause of injury among older adults, often resulting from dynamic balance disturbances. It is influenced by a complex interplay of intrinsic and extrinsic fall-risk factors. To identify individual fall risks, it is important to understand the underlying associations.</p><p><strong>Objective: </strong>This study aimed to build an experimental setup modeling selected factors leading to a loss of balance, measured by the margin of stability (MoS) in an ecologically valid real-world example (tripping). Additionally, these analyses aimed to assess the feasibility and safety of the protocol and to explore the use of the MoS as part of a prototypical dynamic fall-risk model to differentiate between fall-risk groups.</p><p><strong>Methods: </strong>Nineteen community-dwelling older adults (mean age of 71, SD 3.67 y; n=7, 37% women) completed the tripping protocol involving perturbations under various conditions. Clinical assessments were used to identify relevant fall-related intrinsic fall-risk factors. MoS was measured using an 8-camera motion capture system. Receiver operating characteristic analyses determined the ability of MoS to distinguish between low and high fall-risk groups.</p><p><strong>Results: </strong>Approximately one-quarter of participants discontinued before or at the start of the tripping scenario because of discomfort or fear of perturbations, indicating that perceived safety is an important feasibility factor. Perturbations significantly disrupted MoS, with a median MoS of -106.05 (IQR -181.40 to -41.50) mm during the perturbed step compared to 114 (IQR 81.20-155.20) mm in the preperturbation step. Recovery steps showed progressive stabilization, with the second recovery step achieving a median MoS of 88.45 (IQR 47.50-137.80) mm. The second recovery step exhibited the highest predictive accuracy for fall-risk differentiation, with area under the curve values reaching 82.3% during slow walking with a series of right-sided perturbations. In contrast, fast walking with random perturbations yielded lower area under the curve values (64.9%). Slow walking conditions generally demonstrated the clearest separation between fall-risk groups.</p><p><strong>Conclusions: </strong>This pilot and feasibility study demonstrates the applicability of a tripping paradigm to perturb MoS in older adults and provides preliminary insights into its association with fall-risk indices. While the protocol proved safe and feasible for fit older adults, perceived safety limited full participation. The findings are exploratory and intended to guide the design of larger prospective studies rather than to establish predictive conclusions. These data suggest that MoS during controlled tripping may help differentiate fall-risk strata, but confirmation will require adequately powered studies in more diverse and frailer older populations-and across multiple real-world scenarios-before any clinical implementation can ","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":"10 ","pages":"e74418"},"PeriodicalIF":2.0,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12875566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146124970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Registered dietitian nutritionists (RDNs)-referred to as registered dietitians in Japan-contribute to disease management, prevention of complications, and improvement in quality of life through individualized nutritional guidance. However, these techniques often rely on individual experience, leading to variations in quality. The nutrition care process provides a standardized framework for nutritional care, but the specific techniques used in clinical practice and their interrelationships remain unclear. Interpretive structural modeling (ISM) is a method that visualizes and hierarchically organizes interrelationships among multiple elements, making it useful for structuring complex practical skills. Therefore, clarifying the structure of nutritional guidance techniques may support the standardization of practice and the development of educational frameworks.
Objective: This study aimed to identify the elements influencing nutritional guidance techniques in clinical practice, clarify their hierarchical structure using ISM, and explore their potential applicability to the education of registered dietitians.
Methods: Three experienced RDNs participated in an expert panel. Elements influencing nutritional guidance techniques were identified through structured brainstorming and consensus-building sessions. The extracted elements were analyzed using ISM to generate a reachability matrix and derive a hierarchical structure that visualized the interrelationships among the elements.
Results: A total of 14 elements were identified and organized into a 6-level hierarchical structure. The upper levels included nutrition care process-related elements, with the "nutritional intervention plan" positioned at the top, whereas the lower levels consisted of foundational elements such as "clinical knowledge" and "understanding of patient background."
Conclusions: This study identified 14 elements influencing nutritional guidance techniques in clinical practice and systematically visualized their interrelationships as a 6-level hierarchy using ISM. The resulting model provides an initial framework that may inform the development of clinical education curricula and competency evaluation frameworks for RDNs, and it could contribute to the advancement of standardized approaches in nutritional guidance education.
{"title":"Identifying the Structure and Elements of Nutritional Guidance Techniques: Cross-Sectional Analytic Hierarchy Study.","authors":"Machiko Ukai, Mikiko Kanno, Rui Sudo, Miyako Ogawa, Kazuki Ohashi, Katsuhiko Ogasawara","doi":"10.2196/83185","DOIUrl":"10.2196/83185","url":null,"abstract":"<p><strong>Background: </strong>Registered dietitian nutritionists (RDNs)-referred to as registered dietitians in Japan-contribute to disease management, prevention of complications, and improvement in quality of life through individualized nutritional guidance. However, these techniques often rely on individual experience, leading to variations in quality. The nutrition care process provides a standardized framework for nutritional care, but the specific techniques used in clinical practice and their interrelationships remain unclear. Interpretive structural modeling (ISM) is a method that visualizes and hierarchically organizes interrelationships among multiple elements, making it useful for structuring complex practical skills. Therefore, clarifying the structure of nutritional guidance techniques may support the standardization of practice and the development of educational frameworks.</p><p><strong>Objective: </strong>This study aimed to identify the elements influencing nutritional guidance techniques in clinical practice, clarify their hierarchical structure using ISM, and explore their potential applicability to the education of registered dietitians.</p><p><strong>Methods: </strong>Three experienced RDNs participated in an expert panel. Elements influencing nutritional guidance techniques were identified through structured brainstorming and consensus-building sessions. The extracted elements were analyzed using ISM to generate a reachability matrix and derive a hierarchical structure that visualized the interrelationships among the elements.</p><p><strong>Results: </strong>A total of 14 elements were identified and organized into a 6-level hierarchical structure. The upper levels included nutrition care process-related elements, with the \"nutritional intervention plan\" positioned at the top, whereas the lower levels consisted of foundational elements such as \"clinical knowledge\" and \"understanding of patient background.\"</p><p><strong>Conclusions: </strong>This study identified 14 elements influencing nutritional guidance techniques in clinical practice and systematically visualized their interrelationships as a 6-level hierarchy using ISM. The resulting model provides an initial framework that may inform the development of clinical education curricula and competency evaluation frameworks for RDNs, and it could contribute to the advancement of standardized approaches in nutritional guidance education.</p>","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":"10 ","pages":"e83185"},"PeriodicalIF":2.0,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12875424/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
<p><strong>Background: </strong>In the United Kingdom, there was an increased demand for young people's mental health helpline services during COVID-19 pandemic, when face-to-face services were often inaccessible. Despite this, there is scant research examining young people's experiences with these helplines during the pandemic and postpandemic periods.</p><p><strong>Objective: </strong>Using a cross-sectional survey, this mixed methods study aims to examine young people's (aged 16-25+ years) experiences with the multichannel helpline provided by The Mix (Mental Health Innovations), the United Kingdom's leading online mental health support service for young people during and after the pandemic.</p><p><strong>Methods: </strong>From February 2020 to October 2023, approximately 16,000 users aged 16-25+ years contacted The Mix's helpline. All users were sent an email by The Mix following helpline contact to answer their user survey. Of these, 796 participants aged 16-25+ years answered the survey, representing a response rate of 5%, with a survey completion rate of 65.3%. To address potential nonresponse bias and missing data concerns, a multiple imputation procedure using the Multiple Imputation by Chained Equations (MICE) package in R (R Core Team) provided a final imputed sample for both the pandemic (n=295) and postpandemic (n=501) periods. Open-ended survey responses from users were also explored. Of the 796 participants who responded to the survey, there were 1183 open-ended responses from 486 respondents. Of these, a total of 731 open-ended responses (approximately 60% of the total responses) were coded. The criteria for inclusion were applied by 2 independent coders. Excluded responses focused on single words (eg, "thanks"), irrelevant text, or duplicated entries, ensuring only responses containing substantive feedback were analyzed.</p><p><strong>Results: </strong>During the pandemic, young people who contacted the helpline reported greater satisfaction after the first lockdown and a stronger perceived impact on their well‑being after the first lockdown and during the second and third lockdowns, compared with those who contacted the helpline during the gradual easing period; phone users reported higher satisfaction than those using the contact form. Postpandemic, helpline users who identified as "other" in terms of their gender reported less satisfaction, while male users reported a greater impact on their well-being compared to female users. Qualitative analysis revealed how the participants felt supported by the helpline, such as "feeling heard" and "being empowered," and areas for improvement across service delivery, protocol, and technicalities.</p><p><strong>Conclusions: </strong>The findings highlight the important role that helplines play in supporting young people's mental health, particularly in crises like the pandemic. This study underscores the need for service improvements to ensure young people continue to feel supported by hel
{"title":"Young People's Satisfaction With and Perceived Impact of a Multichannel Mental Health Helpline During and After COVID-19 Pandemic: Mixed Methods Analysis of Cross-Sectional Survey Data.","authors":"Shyn Wei Phua, Anya Jan, Guanlin Zheng, Leslie Morrison Gutman","doi":"10.2196/68507","DOIUrl":"10.2196/68507","url":null,"abstract":"<p><strong>Background: </strong>In the United Kingdom, there was an increased demand for young people's mental health helpline services during COVID-19 pandemic, when face-to-face services were often inaccessible. Despite this, there is scant research examining young people's experiences with these helplines during the pandemic and postpandemic periods.</p><p><strong>Objective: </strong>Using a cross-sectional survey, this mixed methods study aims to examine young people's (aged 16-25+ years) experiences with the multichannel helpline provided by The Mix (Mental Health Innovations), the United Kingdom's leading online mental health support service for young people during and after the pandemic.</p><p><strong>Methods: </strong>From February 2020 to October 2023, approximately 16,000 users aged 16-25+ years contacted The Mix's helpline. All users were sent an email by The Mix following helpline contact to answer their user survey. Of these, 796 participants aged 16-25+ years answered the survey, representing a response rate of 5%, with a survey completion rate of 65.3%. To address potential nonresponse bias and missing data concerns, a multiple imputation procedure using the Multiple Imputation by Chained Equations (MICE) package in R (R Core Team) provided a final imputed sample for both the pandemic (n=295) and postpandemic (n=501) periods. Open-ended survey responses from users were also explored. Of the 796 participants who responded to the survey, there were 1183 open-ended responses from 486 respondents. Of these, a total of 731 open-ended responses (approximately 60% of the total responses) were coded. The criteria for inclusion were applied by 2 independent coders. Excluded responses focused on single words (eg, \"thanks\"), irrelevant text, or duplicated entries, ensuring only responses containing substantive feedback were analyzed.</p><p><strong>Results: </strong>During the pandemic, young people who contacted the helpline reported greater satisfaction after the first lockdown and a stronger perceived impact on their well‑being after the first lockdown and during the second and third lockdowns, compared with those who contacted the helpline during the gradual easing period; phone users reported higher satisfaction than those using the contact form. Postpandemic, helpline users who identified as \"other\" in terms of their gender reported less satisfaction, while male users reported a greater impact on their well-being compared to female users. Qualitative analysis revealed how the participants felt supported by the helpline, such as \"feeling heard\" and \"being empowered,\" and areas for improvement across service delivery, protocol, and technicalities.</p><p><strong>Conclusions: </strong>The findings highlight the important role that helplines play in supporting young people's mental health, particularly in crises like the pandemic. This study underscores the need for service improvements to ensure young people continue to feel supported by hel","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":"10 ","pages":"e68507"},"PeriodicalIF":2.0,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12872607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146118932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cyril Varghese, Jianwei Zhang, Sara Charney, Abdelmohaymin Abdalla, Elizabeth Reeves, Stacy Holyfield, Adam Brown, Michelle Higgins, Hunter Stearns, Julie Liss, Nan Zhang, Diana Orbelo, Rebecca Pittelko, Lindsay Rigelman, Victor Ortega, David Lott, Visar Berisha
Background: Aspiration causes or aggravates a variety of respiratory diseases. Subjective bedside evaluations of aspiration are limited by poor inter- and intra-rater reliability, while gold standard diagnostic tests for aspiration, such as video fluoroscopic swallow study (VFSS) and fiberoptic endoscopic evaluation of swallowing (FEES), are cumbersome or invasive and healthcare resource intensive.
Objective: To develop and validate a novel machine learning algorithm that can analyze simple vowel phonations, to aid in predicting aspiration risk.
Methods: Recorded [i] phonations during routine nasal endoscopy from 163 unique patients were retrospectively analyzed for acoustic features including pitch, jitter, shimmer, harmonic to noise ratio (HNR), and others. Supervised machine learning (ML) was performed on the vowel phonations of those at high-risk for aspiration versus those at low-risk for aspiration. Ground truth of aspiration risk classification for model development was established using VFSS. The performance of the ML model was tested on an independent, external cohort of patient voice samples. The performance of trained Speech Language Pathologists (SLPs) to categorize high versus low-risk aspirators by listening to phonations was compared against the ML model.
Results: Mean ML risk score for those with the ground truth of high versus low aspiration risk was 0.530+ 0.310 vs 0.243+0.249, which was a significant difference (0.287, 95% CI: 0.192-0.381) p<0.001. In the development cohort, the model showed an area under the curve (AUC) for the Receiver Operator Characteristic (ROC) of 0.76 (0.67-0.84) with specificity of 0.76 and F1 score of 0.63. The performance of the model in an external testing cohort was comparable, with AUC of 0.70 (0.52-0.88) with a specificity of 0.81, and F1 score of 0.67. The ML model had comparable accuracy, sensitivity, specificity, negative and positive predictive values compared to trained SLPs in classifying aspiration risk by evaluating vowel phonations.
Conclusions: Otolaryngology (ENT) patients at high risk for aspiration have quantifiable voice characteristics that significantly differ from those who are at a low risk for aspiration, as detected by a ML model trained to analyze sustained phonation and tested on an independent cohort.
Clinicaltrial:
背景:误吸可引起或加重多种呼吸道疾病。吸入性的主观床边评估受到较差的内部和内部可靠性的限制,而吸入性的金标准诊断测试,如视频透视吞咽研究(VFSS)和纤维内镜吞咽评估(FEES),是繁琐的或侵入性的,并且需要大量的医疗资源。目的:开发并验证一种新的机器学习算法,该算法可以分析简单的元音发音,以帮助预测误吸风险。方法:回顾性分析163例患者在常规鼻内镜检查中记录的[i]发声的声学特征,包括音高、抖动、闪烁、谐波噪声比(HNR)等。对高危误吸者和低风险误吸者的元音发音进行监督机器学习(ML)。利用VFSS建立了模型开发中误吸风险分类的真值。机器学习模型的性能在独立的外部队列患者语音样本上进行了测试。训练有素的语音语言病理学家(slp)通过听发音对高风险和低风险吸入器进行分类的表现与ML模型进行比较。结果:高、低误吸风险的平均ML风险评分为0.530+ 0.310 vs 0.243+0.249,差异有统计学意义(0.287,95% CI: 0.192-0.381)。结论:耳鼻喉科(ENT)的高误吸风险患者具有可量化的语音特征,与低误吸风险的患者有显著差异,这是经过训练分析持续发声的ML模型所检测到的,并在独立队列中进行了测试。临床试验:
{"title":"Development and Validation of a Machine Learning Model That Uses Voice to Predict Aspiration Risk.","authors":"Cyril Varghese, Jianwei Zhang, Sara Charney, Abdelmohaymin Abdalla, Elizabeth Reeves, Stacy Holyfield, Adam Brown, Michelle Higgins, Hunter Stearns, Julie Liss, Nan Zhang, Diana Orbelo, Rebecca Pittelko, Lindsay Rigelman, Victor Ortega, David Lott, Visar Berisha","doi":"10.2196/86069","DOIUrl":"10.2196/86069","url":null,"abstract":"<p><strong>Background: </strong>Aspiration causes or aggravates a variety of respiratory diseases. Subjective bedside evaluations of aspiration are limited by poor inter- and intra-rater reliability, while gold standard diagnostic tests for aspiration, such as video fluoroscopic swallow study (VFSS) and fiberoptic endoscopic evaluation of swallowing (FEES), are cumbersome or invasive and healthcare resource intensive.</p><p><strong>Objective: </strong>To develop and validate a novel machine learning algorithm that can analyze simple vowel phonations, to aid in predicting aspiration risk.</p><p><strong>Methods: </strong>Recorded [i] phonations during routine nasal endoscopy from 163 unique patients were retrospectively analyzed for acoustic features including pitch, jitter, shimmer, harmonic to noise ratio (HNR), and others. Supervised machine learning (ML) was performed on the vowel phonations of those at high-risk for aspiration versus those at low-risk for aspiration. Ground truth of aspiration risk classification for model development was established using VFSS. The performance of the ML model was tested on an independent, external cohort of patient voice samples. The performance of trained Speech Language Pathologists (SLPs) to categorize high versus low-risk aspirators by listening to phonations was compared against the ML model.</p><p><strong>Results: </strong>Mean ML risk score for those with the ground truth of high versus low aspiration risk was 0.530+ 0.310 vs 0.243+0.249, which was a significant difference (0.287, 95% CI: 0.192-0.381) p<0.001. In the development cohort, the model showed an area under the curve (AUC) for the Receiver Operator Characteristic (ROC) of 0.76 (0.67-0.84) with specificity of 0.76 and F1 score of 0.63. The performance of the model in an external testing cohort was comparable, with AUC of 0.70 (0.52-0.88) with a specificity of 0.81, and F1 score of 0.67. The ML model had comparable accuracy, sensitivity, specificity, negative and positive predictive values compared to trained SLPs in classifying aspiration risk by evaluating vowel phonations.</p><p><strong>Conclusions: </strong>Otolaryngology (ENT) patients at high risk for aspiration have quantifiable voice characteristics that significantly differ from those who are at a low risk for aspiration, as detected by a ML model trained to analyze sustained phonation and tested on an independent cohort.</p><p><strong>Clinicaltrial: </strong></p>","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146118906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ian-C Jung, Maria Zerlik, Katharina Schuler, Martin Sedlmayr, Brita Sedlmayr
<p><strong>Background: </strong>The integration of artificial intelligence (AI) into clinical decision support systems (CDSSs) for mechanical ventilation in intensive care units (ICUs) holds great potential. However, the lack of transparency and explainability hinders the adoption of opaque AI models in clinical practice. Explanation user interfaces (XUIs), incorporating explainable AI algorithms, are considered a key solution to enhance trust and usability. Despite growing research on explainable AI in health care, little is known about how clinicians perceive and interact with such explanation interfaces in high-stakes environments such as the ICU. Addressing this gap is essential to ensure that AI-supported CDSS are not only accurate but also trusted, interpretable, and seamlessly integrated into clinical workflows.</p><p><strong>Objective: </strong>This study aimed to evaluate the first iteration of the design and evaluation phase of an XUI for an AI-based CDSS intended to optimize mechanical ventilation in the ICU. Specifically, it explores how different user groups-ICU nurses and physicians-perceive and prioritize explanation concepts, providing the empirical foundation for subsequent refinement iterations.</p><p><strong>Methods: </strong>A midfidelity prototype was developed using the prototyping software Justinmind, based on existing guidelines, scientific literature, and insights from previous user-centered design (UCD) phases. The design process followed ISO (International Organization for Standardization) 9241-210 principles for UCD and combined qualitative and quantitative feedback to identify usability strengths, design challenges, and role-specific explanation needs. The prototype was evaluated formatively through 2 usability walkthroughs (walkthrough 1: 4 resident physicians and walkthrough 2: 4 ICU nurses), which included guided group discussions and Likert-scale assessments of explanation concepts in terms of understandability, suitability, and visual appeal.</p><p><strong>Results: </strong>The XUI was structured into 2 levels: a first level displaying high-level explanations (outlier warning and output certainty) alongside the CDSS output, and a second level offering more detailed explanations (available input, feature importance, and rule-based explanation) for users seeking deeper insight. While both user groups appreciated the first level, physicians found the second level of the XUI useful, whereas ICU nurses found it overly detailed. Thus, the structure was able to address the differing needs for explanations. The layered design helped balance transparency and information overload by providing initially concise explanations and more detailed ones on demand. The evaluation further strengthened evidence for role-dependent explanation needs, suggesting that nurses prefer actionable, concise insights, whereas physicians benefit from more granular transparency information.</p><p><strong>Conclusions: </strong>This study underscor
{"title":"An Explanation User Interface for Artificial Intelligence-Supported Mechanical Ventilation Optimization for Clinicians: User-Centered Design and Formative Usability Study.","authors":"Ian-C Jung, Maria Zerlik, Katharina Schuler, Martin Sedlmayr, Brita Sedlmayr","doi":"10.2196/77481","DOIUrl":"https://doi.org/10.2196/77481","url":null,"abstract":"<p><strong>Background: </strong>The integration of artificial intelligence (AI) into clinical decision support systems (CDSSs) for mechanical ventilation in intensive care units (ICUs) holds great potential. However, the lack of transparency and explainability hinders the adoption of opaque AI models in clinical practice. Explanation user interfaces (XUIs), incorporating explainable AI algorithms, are considered a key solution to enhance trust and usability. Despite growing research on explainable AI in health care, little is known about how clinicians perceive and interact with such explanation interfaces in high-stakes environments such as the ICU. Addressing this gap is essential to ensure that AI-supported CDSS are not only accurate but also trusted, interpretable, and seamlessly integrated into clinical workflows.</p><p><strong>Objective: </strong>This study aimed to evaluate the first iteration of the design and evaluation phase of an XUI for an AI-based CDSS intended to optimize mechanical ventilation in the ICU. Specifically, it explores how different user groups-ICU nurses and physicians-perceive and prioritize explanation concepts, providing the empirical foundation for subsequent refinement iterations.</p><p><strong>Methods: </strong>A midfidelity prototype was developed using the prototyping software Justinmind, based on existing guidelines, scientific literature, and insights from previous user-centered design (UCD) phases. The design process followed ISO (International Organization for Standardization) 9241-210 principles for UCD and combined qualitative and quantitative feedback to identify usability strengths, design challenges, and role-specific explanation needs. The prototype was evaluated formatively through 2 usability walkthroughs (walkthrough 1: 4 resident physicians and walkthrough 2: 4 ICU nurses), which included guided group discussions and Likert-scale assessments of explanation concepts in terms of understandability, suitability, and visual appeal.</p><p><strong>Results: </strong>The XUI was structured into 2 levels: a first level displaying high-level explanations (outlier warning and output certainty) alongside the CDSS output, and a second level offering more detailed explanations (available input, feature importance, and rule-based explanation) for users seeking deeper insight. While both user groups appreciated the first level, physicians found the second level of the XUI useful, whereas ICU nurses found it overly detailed. Thus, the structure was able to address the differing needs for explanations. The layered design helped balance transparency and information overload by providing initially concise explanations and more detailed ones on demand. The evaluation further strengthened evidence for role-dependent explanation needs, suggesting that nurses prefer actionable, concise insights, whereas physicians benefit from more granular transparency information.</p><p><strong>Conclusions: </strong>This study underscor","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":"10 ","pages":"e77481"},"PeriodicalIF":2.0,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146113197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
<p><strong>Background: </strong>Poor sleep is a concerning public health problem in the United States. Previous sleep interventions often face barriers such as high costs, limited accessibility, and low user engagement. Recent advancements in artificial intelligence (AI) technologies offer a novel approach to overcoming these limitations. In response, our team developed a prototype AI sleep chatbot powered by a large language model to deliver personalized, accessible sleep support.</p><p><strong>Objective: </strong>This study aimed to examine the feasibility, usability, acceptability, and preliminary efficacy of the AI chatbot for sleep promotion.</p><p><strong>Methods: </strong>We conducted a quasi-experimental, single-group study with adults in the United States aged 18 to 75 years who self-reported poor sleep. The chatbot was integrated into a commercially available messaging app. Participants were asked to engage with a virtual sleep therapist via texting over 2 weeks. The chatbot provided ongoing, individualized sleep guidance and adapted recommendations based on participants' prior conversations. Feasibility, usability, and acceptability were descriptively summarized. Sleep was assessed using questionnaires before and after the intervention.</p><p><strong>Results: </strong>Of the 107 adults who enrolled in the study, 88 (82.2%) completed chatbot registration. Among these 88 participants, 65 (73.9%) initiated interactions, and 44 (50%) completed the 2-week intervention. The final analysis included 42 adults (mean age 36, SD 11 years; n=12, 28.6% male). On average, participants engaged with the chatbot for 58 (SD 42) minutes, with each chat session lasting approximately 9 (SD 6) minutes. Most reported favorable experiences with the chatbot. The average usability score was 85.2 (SD 10.7) out of 100, which was well above the benchmark of 68. The chatbot was rated as highly acceptable, with a satisfaction score of 27.3 (SD 4.1) out of 32. All participants perceived the chatbot as effective, with ratings ranging from "slightly effective" to "extremely effective." The preliminary evidence showed improved sleep outcomes after chatbot use: total sleep time increased by 1.4 hours (P<.001); sleep onset latency decreased by 30.9 minutes (P<.001); sleep efficiency increased by 7.8% (P=.007); and scores improved for perceived sleep quality (mean difference [MD] -5.4; P<.001), insomnia severity (MD -7.9; P<.001), daytime sleepiness (MD -4.7; P<.001), and sleep hygiene skills (MD -13.2; P<.001). No significant change was observed in sleep environment (MD -1.1; P=.16).</p><p><strong>Conclusions: </strong>Our AI chatbot demonstrated satisfactory feasibility, usability, and acceptability. Improvements were observed following chatbot use, although causality cannot be established. These findings highlight the potential of integrating state-of-the-art large language models into behavioral interventions for sleep promotion. Future research should include objectiv
{"title":"Assessing the Feasibility, Usability, Acceptability, and Efficacy of an AI Chatbot for Sleep Promotion: Quasi-Experimental Study.","authors":"Xiaoyue Liu, Jingchen Liu","doi":"10.2196/84023","DOIUrl":"https://doi.org/10.2196/84023","url":null,"abstract":"<p><strong>Background: </strong>Poor sleep is a concerning public health problem in the United States. Previous sleep interventions often face barriers such as high costs, limited accessibility, and low user engagement. Recent advancements in artificial intelligence (AI) technologies offer a novel approach to overcoming these limitations. In response, our team developed a prototype AI sleep chatbot powered by a large language model to deliver personalized, accessible sleep support.</p><p><strong>Objective: </strong>This study aimed to examine the feasibility, usability, acceptability, and preliminary efficacy of the AI chatbot for sleep promotion.</p><p><strong>Methods: </strong>We conducted a quasi-experimental, single-group study with adults in the United States aged 18 to 75 years who self-reported poor sleep. The chatbot was integrated into a commercially available messaging app. Participants were asked to engage with a virtual sleep therapist via texting over 2 weeks. The chatbot provided ongoing, individualized sleep guidance and adapted recommendations based on participants' prior conversations. Feasibility, usability, and acceptability were descriptively summarized. Sleep was assessed using questionnaires before and after the intervention.</p><p><strong>Results: </strong>Of the 107 adults who enrolled in the study, 88 (82.2%) completed chatbot registration. Among these 88 participants, 65 (73.9%) initiated interactions, and 44 (50%) completed the 2-week intervention. The final analysis included 42 adults (mean age 36, SD 11 years; n=12, 28.6% male). On average, participants engaged with the chatbot for 58 (SD 42) minutes, with each chat session lasting approximately 9 (SD 6) minutes. Most reported favorable experiences with the chatbot. The average usability score was 85.2 (SD 10.7) out of 100, which was well above the benchmark of 68. The chatbot was rated as highly acceptable, with a satisfaction score of 27.3 (SD 4.1) out of 32. All participants perceived the chatbot as effective, with ratings ranging from \"slightly effective\" to \"extremely effective.\" The preliminary evidence showed improved sleep outcomes after chatbot use: total sleep time increased by 1.4 hours (P<.001); sleep onset latency decreased by 30.9 minutes (P<.001); sleep efficiency increased by 7.8% (P=.007); and scores improved for perceived sleep quality (mean difference [MD] -5.4; P<.001), insomnia severity (MD -7.9; P<.001), daytime sleepiness (MD -4.7; P<.001), and sleep hygiene skills (MD -13.2; P<.001). No significant change was observed in sleep environment (MD -1.1; P=.16).</p><p><strong>Conclusions: </strong>Our AI chatbot demonstrated satisfactory feasibility, usability, and acceptability. Improvements were observed following chatbot use, although causality cannot be established. These findings highlight the potential of integrating state-of-the-art large language models into behavioral interventions for sleep promotion. Future research should include objectiv","PeriodicalId":14841,"journal":{"name":"JMIR Formative Research","volume":"10 ","pages":"e84023"},"PeriodicalIF":2.0,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146113217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}