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The aggregation of β-amyloid peptide (Aβ) is associated with neurodegenerative diseases such as Alzheimer's disease (AD). Several therapies aimed at reducing the aggregation of this peptide have emerged as potential strategies for the treatment of AD. This paper describes the design and preparation of new hybrid molecules based on steroids, selenosugars, and [60]fullerene as potential inhibitors of Aβ oligomerization. These moieties were selected based on their antioxidant properties and possible areas of interaction with the Aβ. Cyclopropanations between C₆₀ and malonates bearing different steroid and selenosugar moieties using the Bingel-Hirsch protocol have enabled the synthesis of functionalized molecular hybrids. The obtained derivatives were characterized by physical and spectroscopic techniques. Theoretical calculations for all the selenium compounds were performed using the density functional theory DFT/B3LYP-D3(BJ)/6-311G(2d,p) predicting the most stable conformations of the synthesized derivatives. Relevant geometrical parameters were investigated to relate the stereochemical behavior and the spectroscopic data obtained. The affinity of the compounds for Aβ-peptide was estimated by molecular docking simulation, which predicted an increase in affinity and interactions for Aβ for the hybrids containing the C₆₀ core. In addition, parameters such as lipophilicity, polar surface area, and dipole moment were calculated to predict their potential interaction with membrane cells.

After understanding the biological signaling roles of hydrogen sulfide and its involvement in various physiological processes, there has been enormous interest in exploring its therapeutic utility in areas such as cancer, inflammation, cardiovascular diseases, etc. There is also growing interest in using suitable H₂S donors in combination with other drugs to improve the treatment outcome through the modulation of multiple pathways. The premature release of H₂S from small molecule donors and the difficulty in controlling its spatio-temporal distribution are the major challenges during these efforts. Hence the development of appropriate carriers that can release this gasotransmitter along with the therapeutic entity of interest in a controlled manner has high significance. In this regard, this report presents a novel drug delivery system from oxanorbornane-based synthetic lipids that carries a H₂S-releasing 1,2-dithiole-3-thione moiety as part of the head group. Nanoaggregates of the resulting conjugate are not only capable of efficiently entrapping a non-steroidal anti-inflammatory drug such as ibuprofen, but also release this drug and H₂S in a controlled and sequential manner.

The development of platform chemicals derived from biomass, in particular, 5-hydroxymethylfurfural (5-HMF) and furfural (FUR), is of crucial importance in biorefinery. Over the past decades, metal-supported nanostructured zeolites, in particular, metal-supported hierarchically porous zeolites or metal-encapsulated zeolites, have been extensively elaborated because of their multiple functionalities and superior properties, for example, shape-selectivity, (hydro)thermal stability, tunable acidity and basicity, redox properties, improved diffusion, and intimacy of multiple active sites. In this review, the effects of such properties of metal-supported nanostructured zeolites on the enhanced catalytic performances in furanic compound upgrading are discussed. In addition, the recent rational design of metal-supported nanostructured zeolites is exemplified. Consequently, the ongoing challenges for further developing metal-supported nanostructured zeolites-based catalysts and their applications in HMF and FUR upgrading are identified.

The gel skeletal reinforcement (GSR) method was applied at the preparation stage of β-zeolite to prepare a novel hierarchical catalyst. A solution of hexamethyldisiloxane (HMDS) and acetic anhydride, a GSR reagent, was added to the mixture of colloidal silica, sodium aluminate, tetraethylammonium hydroxide, sodium hydroxide and water, and successive aging and hydrothermal treatment gave microporous β-zeolite surrounded by mesoporous silica like core-shell structure. Its properties were characterized by XRD, nitrogen adsorption and desorption, NH₃-TPD, TEM, and TG-DTA measurements, and further characteristics of the catalysts produced were clarified by the catalytic cracking of n-dodecane. The hierarchical structure of microporous zeolite and mesoporous silica was shown from GSR-2.9HS-H-Beta to GSR-3.2HS-H-Beta, where the molar ratio of HMDS and silica source of β-zeolite was 2.9~3.2 : 100. It was found that in the catalytic cracking of n-dodecane, the relative activity (the conversion per the amount of zeolite crystals) increased with the increase in mesopore volume and surface area. The result indicated that the introduction of mesopores was effective even in catalytic cracking of small molecule of n-dodecane.

The organic-inorganic hybrid fluorescent hyperbranched polymer, including hyperbranched polysiloxane and hyperbranched polyborate, have attracted much attention due to their excellent optical properties and wide range of applications. Hyperbranched polysiloxane and polyborates, prepared by introducing Si or B elements into organic polymer chains at the molecular level through rational molecular design and novel synthesis methods, exhibit outstanding photophysical properties as an indispensable branch of organic-inorganic hybrid fluorescent materials. Herein, this review highlights the recent research progress on hyperbranched polysiloxanes and hyperbranched polyborates, including strategies for regulating their emission wavelengths, quantum yields, and fluorescence lifetimes, potential emission mechanisms, and various applications. Finally, some challenges and promising future directions in the field of organic-inorganic hybrid fluorescent polymers are summarized.

This study focuses on the sustainable production of bio-jet fuel through the catalytic hydrodeoxygenation (HDO) of isoeugenol (IE). Sucrose-based activated carbon supported bimetallic Platinum-Tin metal sulphides (PtO-SnS/AC) catalyst was prepared for HDO process. Physicochemical properties of catalysts with different spraying synthesis methods (in situ and ex situ metal doping) and Pt loading (0.1-1.0 %) were further investigated. The PtO-SnS/AC catalysts were characterised using various techniques such as X-ray absorption spectroscopy (XAS), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), high-resolution transmission electron microscopy (HRTEM), field-emission scanning electron microscopy (FESEM) and thermogravimetric analysis (TGA). Both HRTEM and FESEM results show the successful preparation of a spherical nanoparticles doped over activated carbon, and Pt was dispersed on the outer shell of the particles. The catalytic HDO of IE was evaluated in a batch system and showed a high yield and conversion as follows: IE conversion of 100 %, liquid-phase mass balance of 95.92 %, dihydroeugenol (DH) conversion of 99.32 %, propylcyclohexane (PCH) yield of 88.94 % and 2-methoxy-4-propylcyclohexanol (HYD) yield of 76.19 %. Moreover, the PtO-SnS/AC catalyst exhibited high reusability with low metal leaching and high coke resistance for 10 cycles. The catalyst was evaluated in a continuous flow reactor for 100 h at different reaction temperatures, and interestingly, the catalyst showed low deactivation with a high half-time.

Electrochemical water oxidation utilizing bimetallic CoNi-Tz (Tz=1,2,4-triazole) framework is explored. Initially, CoNi-Tz possesses active tetrahedral Co center and electron-mediated octahedral Ni chain. After performing an electrochemical activation, the partial structural transformation on the Ni center occurs. This leads to the generation of excessive active centers which can promote catalytic activity of the framework. The activated CoNi-Tz catalyst displays a remarkably low OER overpotential of 293 mV at a current density of 10 mA cm^-2 with a small Tafel slope of 49.98 mV dec^-1, outperforming the single metal Co-Tz and benchmark IrO₂ catalysts.

Microorganisms, including fungi, bacteria, cyanobacteria, and algae, frequently colonize the surfaces of cultural heritage materials. These biological agents can cause biodeterioration through various mechanisms, resulting in aesthetic alteration, physical disruption, or compromise of mechanical integrity. To assess the presence and diversity of microorganisms, a combination of microscopy techniques is commonly used in conjunction with results from both culture-dependent and culture-independent methods. However, microbial populations are often underestimated. To address this issue, microorganisms can be detected by their intrinsic fluorescence, which can be observed via fluorescence microscopy. This approach facilitates the mapping of the spatial arrangement of microorganisms and the understanding of colonization patterns, thereby complementing established imaging techniques and providing insight into the interactions of microbial communities with the substrate. Given the limited research in this area, we examine the potential of microorganism autofluorescence as a molecular tool for investigating biodeterioration in artistic and architectural heritage, with a particular focus on paper and stone materials. Identifying and understanding the diverse microbiota that may be present is crucial for developing tailored and effective preventive measures and conservation treatments, as some of the species discovered may pose significant risks to both artifacts and human health.

Waste, often overlooked, stands out as a prime source of valuable products, meeting the demand for natural resources. In the face of environmental challenges, this study explores the crucial role of waste-derived catalysts in sustainable practices, emphasizing the transformative potential of solid waste materials. Carbon-based catalysts sourced from agricultural, municipal, and industrial waste streams can be transformed into activated carbon, biochar, and hydrochar which are extensively used adsorbents. Furthermore, the paper also highlights the potential of transition metal-based catalysts derived from spent batteries, electronic waste, and industrial byproducts, showcasing their efficacy in environmental remediation processes. Calcium-based catalysts originating from food waste, including seashells, eggshells, bones, as well as industrial and construction waste also find an extensive application in biodiesel production, providing a comprehensive overview of their promising role in sustainable and eco-friendly practices. From mitigating pollutants to recovering valuable resources, waste-derived catalysts exhibit a versatile role in addressing waste management challenges and promoting resource sustainability. By transforming waste into valuable catalysts, this study champions a paradigm shift towards a more sustainable and resource-efficient future.

Nature performs critical physiological functions using a series of structurally and functionally diverse membrane proteins embedded in cell membranes, in which native ion protein channels modify the electrical potential inside and outside the cell membrane through charged ion movements. Consequently, the cell responds to external stimuli, playing an essential role in various life activities, such as nerve excitation conduction, neurotransmitter release, muscle movement, and control of cell differentiation. Supramolecular artificial channels, which mimic native protein channels in structure and function, adopt unimolecular or self-assembled structures, such as crown ethers, cyclodextrins, cucurbiturils, column arenes, cyclic peptide nanotubes, and metal-organic artificial channels, in channel construction strategies. Owing to the various driving forces involved, artificial synthetic ion channels can be divided into artificial cation and anion channels in terms of ion selectivity. Cation selectivity usually originates from ion coordination, whereas anion selectivity is related to hydrogen bonding, ion pairing, and anion-dipole interactions. Several studies have been conducted on artificial cation channels, and several reviews have summarized them in detail; however, the research on anions is still in the initial stages, and related reviews have rarely been reported. Hence, this article primarily focuses on the recent research on anion channels.