Pub Date : 2017-01-01DOI: 10.18869/ACADPUB.JBRMS.4.1.17
L. Bimanand, N. Sadeghifard, F. Jalilian, Hassan Hossainzadegan, Sattar Mohammadi Darbidi, Ali Hemahian, S. Ghafourian, I. Pakzad
Introduction: Escherichia coli (E.coli) as a main cause of both nosocomial and communityacquired infections in humans have a relative potential to develop resistance. Nowadays, most infections caused by ESBL-producing E.coli (ESBLEC) had mostly been described as nosocomial acquired or nursing home related. In this study, we employed E-test assay to detect antibiotic resistance of E.coli strains and determine MIC of antibiotics. Materials and methods: Thirty E.coli strains gathered from Imam Khomeini hospital of Ilam, and cultured on TSB and bacterial suspension prepared by 0.5 μF concentration for Etest. Mueller Hinton agar and E-test strips of Amikacin, Cefepime, Ceftazidime, Ceftriaxone, Gentamicin, Meropenem, Nitrofurantoin, Piperacillin/Tazobactam, Tetracycline, Ticarcillin/ Clavulanic acid, Tobramycin, Trimethoprim were used Results: Resistance to Ceftriaxone, Tobramycin, Gentamicin, Ticarcillin/ Clavulanic, Amikacin were 19.8%, 26.4%, 23.3%, 62.7%, 70.3%, respectively. Conclusion: the results indicated, E.coli strains in this study were high sensitivity to Meropenem ,Nitrofuratoin, Ciprofloxacin , Ceftazidime, Cefepime.
{"title":"E-test antibiotic susceptibility of E.coli strains isolated from hospital acquired infections of Imam Khomeini hospital, Ilam, Iran","authors":"L. Bimanand, N. Sadeghifard, F. Jalilian, Hassan Hossainzadegan, Sattar Mohammadi Darbidi, Ali Hemahian, S. Ghafourian, I. Pakzad","doi":"10.18869/ACADPUB.JBRMS.4.1.17","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBRMS.4.1.17","url":null,"abstract":"Introduction: Escherichia coli (E.coli) as a main cause of both nosocomial and communityacquired infections in humans have a relative potential to develop resistance. Nowadays, most infections caused by ESBL-producing E.coli (ESBLEC) had mostly been described as nosocomial acquired or nursing home related. In this study, we employed E-test assay to detect antibiotic resistance of E.coli strains and determine MIC of antibiotics. Materials and methods: Thirty E.coli strains gathered from Imam Khomeini hospital of Ilam, and cultured on TSB and bacterial suspension prepared by 0.5 μF concentration for Etest. Mueller Hinton agar and E-test strips of Amikacin, Cefepime, Ceftazidime, Ceftriaxone, Gentamicin, Meropenem, Nitrofurantoin, Piperacillin/Tazobactam, Tetracycline, Ticarcillin/ Clavulanic acid, Tobramycin, Trimethoprim were used Results: Resistance to Ceftriaxone, Tobramycin, Gentamicin, Ticarcillin/ Clavulanic, Amikacin were 19.8%, 26.4%, 23.3%, 62.7%, 70.3%, respectively. Conclusion: the results indicated, E.coli strains in this study were high sensitivity to Meropenem ,Nitrofuratoin, Ciprofloxacin , Ceftazidime, Cefepime.","PeriodicalId":15047,"journal":{"name":"Journal of Basic Research in Medical Sciences","volume":"4 1","pages":"17-21"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67673371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.18869/ACADPUB.JBRMS.4.1.45
M. Aryaie, Zahra Khombehbini, F. Bakhsha, Z. Yousefi, Omid Behravesh
Introduction: Musculoskeletal pain accompanied by psychological problem lead to reduce the efficiency of adolescents; so, this study aimed to determine the prevalence of musculoskeletal pain and its association with psychological factors among female adolescents. Materials and methods: The target population of this cross sectional study was female students (3625 in total) from both private and state funded high school children in Gorgan, northern Iran. Self assessment questionnaires were distributed to 255 students across 8 female high schools. Self-report version of the Strengths and Difficulties (SDQ) questionnaires was used to screen adolescents with Psychiatric symptoms. To evaluate musculoskeletal pain Nordic questionnaire and numeric pain rating scale was used. Data were analyzed by binary logistic regression and the cumulative odds ratio (COR) was carried out for the ordinal level of musculoskeletal symptoms. Results: The prevalence rate of neck, shoulder and low back pain was reported, 23.1%, 27.8% and 27.7%, respectively. Hyperactivity-inattention (OR=2. 82; CI: 1.14-6.97) and peer problem (OR= 2.72; CI: 1.01-7.32) had significant relationship with neck pain, and prosocial behaviors (OR= 3.11; CI: 1.09-10.73) were associated with low back pain in the multivariate model. Ordinal regression showed that the increasing numbers of musculoskeletal symptoms related only to prosocial behavior (COR= 2.78; CI: 1.12-6.91). There was no significant association between shoulder pain and psychological factors. Conclusion: Based on the results, psychological factors were associated with musculoskeletal pain; so, it seems suffering from musculoskeletal pain need to be concurrently noticed with mental feeling for more effective response to attenuate pain.
{"title":"Psychological factors related to musculoskeletal pain among Iranian female adolescents","authors":"M. Aryaie, Zahra Khombehbini, F. Bakhsha, Z. Yousefi, Omid Behravesh","doi":"10.18869/ACADPUB.JBRMS.4.1.45","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBRMS.4.1.45","url":null,"abstract":"Introduction: Musculoskeletal pain accompanied by psychological problem lead to reduce the efficiency of adolescents; so, this study aimed to determine the prevalence of musculoskeletal pain and its association with psychological factors among female adolescents. Materials and methods: The target population of this cross sectional study was female students (3625 in total) from both private and state funded high school children in Gorgan, northern Iran. Self assessment questionnaires were distributed to 255 students across 8 female high schools. Self-report version of the Strengths and Difficulties (SDQ) questionnaires was used to screen adolescents with Psychiatric symptoms. To evaluate musculoskeletal pain Nordic questionnaire and numeric pain rating scale was used. Data were analyzed by binary logistic regression and the cumulative odds ratio (COR) was carried out for the ordinal level of musculoskeletal symptoms. Results: The prevalence rate of neck, shoulder and low back pain was reported, 23.1%, 27.8% and 27.7%, respectively. Hyperactivity-inattention (OR=2. 82; CI: 1.14-6.97) and peer problem (OR= 2.72; CI: 1.01-7.32) had significant relationship with neck pain, and prosocial behaviors (OR= 3.11; CI: 1.09-10.73) were associated with low back pain in the multivariate model. Ordinal regression showed that the increasing numbers of musculoskeletal symptoms related only to prosocial behavior (COR= 2.78; CI: 1.12-6.91). There was no significant association between shoulder pain and psychological factors. Conclusion: Based on the results, psychological factors were associated with musculoskeletal pain; so, it seems suffering from musculoskeletal pain need to be concurrently noticed with mental feeling for more effective response to attenuate pain.","PeriodicalId":15047,"journal":{"name":"Journal of Basic Research in Medical Sciences","volume":"4 1","pages":"45-52"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67673356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.18869/ACADPUB.JBRMS.4.1.8
A. A. Jazi, Hadi Abdi, Mohammad Reza Hafezi Ahmadi, J. Cheraghi
Introduction: Cardiac remodeling after myocardial infarction, is associated with progressive ventricular dysfunction and cardiovascular death. The purpose of this study was to examine the effect of endurance exercise training on morphological changes in rat heart tissue following experimental myocardial infarction. Materials and methods: Rats used in this experiment (8-10 weeks old, 235 ± 5 g body weight) after homogenization according to body weight, were randomly divided to three groups: Healthy (Sham), control (Sedentary) and endurance training groups. Myocardial infarction was induced by subcutaneous injection of isoprenaline (150 mg/kg) in two consecutive days with an interval of 24 hours. Endurance training initiated 2 days after infarction and continued for 4 weeks. In order to assess the necrosis lesion and fibrosis tissue, Hematoxylin–Eosin and Masson's trichrome staining were used, respectively. Data were analyzed by using one-way analysis of variance (ANOVA) at P< 0.05 level. Results: The results indicated that subcutaneous injection of isoprenaline, induced myocardial infarction in rat heart tissue. Rate of necrotic lesion in the Endurance training group was significantly higher than Sedentary (control) group (P=0.005). Also, the size of fibrosis tissue in the Endurance training group was significantly higher than the sedentary (control) group (P= 0.001). Conclusion: In general, results of this study showed that 4 weeks of endurance exercise training after myocardial infarction exacerbate tissue injury in rat heart.
{"title":"Effect of endurance exercise training on morphological changes in rat heart tissue following experimental myocardial infarction","authors":"A. A. Jazi, Hadi Abdi, Mohammad Reza Hafezi Ahmadi, J. Cheraghi","doi":"10.18869/ACADPUB.JBRMS.4.1.8","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBRMS.4.1.8","url":null,"abstract":"Introduction: Cardiac remodeling after myocardial infarction, is associated with progressive ventricular dysfunction and cardiovascular death. The purpose of this study was to examine the effect of endurance exercise training on morphological changes in rat heart tissue following experimental myocardial infarction. Materials and methods: Rats used in this experiment (8-10 weeks old, 235 ± 5 g body weight) after homogenization according to body weight, were randomly divided to three groups: Healthy (Sham), control (Sedentary) and endurance training groups. Myocardial infarction was induced by subcutaneous injection of isoprenaline (150 mg/kg) in two consecutive days with an interval of 24 hours. Endurance training initiated 2 days after infarction and continued for 4 weeks. In order to assess the necrosis lesion and fibrosis tissue, Hematoxylin–Eosin and Masson's trichrome staining were used, respectively. Data were analyzed by using one-way analysis of variance (ANOVA) at P< 0.05 level. Results: The results indicated that subcutaneous injection of isoprenaline, induced myocardial infarction in rat heart tissue. Rate of necrotic lesion in the Endurance training group was significantly higher than Sedentary (control) group (P=0.005). Also, the size of fibrosis tissue in the Endurance training group was significantly higher than the sedentary (control) group (P= 0.001). Conclusion: In general, results of this study showed that 4 weeks of endurance exercise training after myocardial infarction exacerbate tissue injury in rat heart.","PeriodicalId":15047,"journal":{"name":"Journal of Basic Research in Medical Sciences","volume":"4 1","pages":"8-16"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67673414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.18869/ACADPUB.JBRMS.4.1.37
Bahareh Soheili, A. Mirzaei, K. Sayemiri, Z. Ghazanfari
Introduction: Cesarean, as a major abdominal surgery, if done without a medical indication, may impose numerous complications on the mothers and the babies and increase frequency of cesarean deliveries in subsequent pregnancies. This study aimed to predict the behavioral tendencies of pregnant women in selecting their delivery approaches, based on the theory of planned behavior (TPB). Materials and methods: This cross-sectional study was performed on 100 pregnant women referred to healthcare centers of Kermanshah city (western Iran). A researcher-made questionnaire was applied, based on TPB constructs including attitudes, perceived behavioral controls, subjective norms, and behavioral tendencies. To analyze the data, Pearson correlation, Spearman, s regression, and ANOVA were used via the SPSS statistical software, version 20. Results: The average age of pregnant woman was 23.7±3.93 years old. The results demonstrated a significant correlation between the subjective norms and behavioral tendencies (r=0.335, P=0.001). A significant relationship was seen between the perceived behavioral controls and tendencies (r=0.277, P=0.004). A significant relationship was found between the perceived behavioral control and the attitude (r=0.293, P=0.002). The results of the regression results demonstrated that the subjective norms and perceived behavioral controls can significantly predict 14.1 percent of changes in the variable of tendencie. Conclusion: The findings indicate the strength of the variable of subjective norms as the most effective factor in predicting the delivery approach; therefore, systematic and planned training seems necessary, not only for the pregnant women, but also the individuals affecting this group. Thus, to reduce caesarean sections, physicians, as an effective factor, need to be urged to boost natural childbirth.
{"title":"Predicting the behavioral intention of pregnant women’s choice of delivery method based on the theory of planned behavior: A cross-sectional study","authors":"Bahareh Soheili, A. Mirzaei, K. Sayemiri, Z. Ghazanfari","doi":"10.18869/ACADPUB.JBRMS.4.1.37","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBRMS.4.1.37","url":null,"abstract":"Introduction: Cesarean, as a major abdominal surgery, if done without a medical indication, may impose numerous complications on the mothers and the babies and increase frequency of cesarean deliveries in subsequent pregnancies. This study aimed to predict the behavioral tendencies of pregnant women in selecting their delivery approaches, based on the theory of planned behavior (TPB). Materials and methods: This cross-sectional study was performed on 100 pregnant women referred to healthcare centers of Kermanshah city (western Iran). A researcher-made questionnaire was applied, based on TPB constructs including attitudes, perceived behavioral controls, subjective norms, and behavioral tendencies. To analyze the data, Pearson correlation, Spearman, s regression, and ANOVA were used via the SPSS statistical software, version 20. Results: The average age of pregnant woman was 23.7±3.93 years old. The results demonstrated a significant correlation between the subjective norms and behavioral tendencies (r=0.335, P=0.001). A significant relationship was seen between the perceived behavioral controls and tendencies (r=0.277, P=0.004). A significant relationship was found between the perceived behavioral control and the attitude (r=0.293, P=0.002). The results of the regression results demonstrated that the subjective norms and perceived behavioral controls can significantly predict 14.1 percent of changes in the variable of tendencie. Conclusion: The findings indicate the strength of the variable of subjective norms as the most effective factor in predicting the delivery approach; therefore, systematic and planned training seems necessary, not only for the pregnant women, but also the individuals affecting this group. Thus, to reduce caesarean sections, physicians, as an effective factor, need to be urged to boost natural childbirth.","PeriodicalId":15047,"journal":{"name":"Journal of Basic Research in Medical Sciences","volume":"4 1","pages":"37-44"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67673293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Test anxiety is a common phenomenon and the problematic concern of the educational system. Scented essentials like lavender (angustifolia) oil and Citrus aurantium (orange flower) oil have positive impact on people's physical and mental condition and anxiety. This study was designed to compare and evaluate the effects of lavender essential oil aroma and Citrus aurantium essential oil aroma on test anxiety. Materials and methods: This double-blind clinical trial study was carried out on 80 female students from the Faculty of Paramedics Sciences, Gorgan city in 2013. Students were randomly and equally assigned to the two lavender or Citrus aurantium groups. All students smelled oil for a period of 60 seconds. To stay scents, some oil was rubbed on the candidates foreheads using an applicator. To evaluate the level of anxiety and stress before the intervention, Sarason Anxiety Test, and to measure the effect of essence after intervention, Visual Analogue Scale (VAS) questionnaire were used. Data were analyzed using SPSS16 software and the independent and paired T-tests. Results: The mean anxiety in students in lavender group dropped from (5.67±2.05) to (3.9± 1.82) and in Citrus aurantium group decreased from (5.25±2.06) to (3.97±2). This difference was statistically significant (P <0.001). The intervention had a significant effect on heart rate; however, had no effect on the blood pressure. Conclusion: According to the results, lavender and citrus aurantium scents had positive effects on students' test anxiety and can be used as a cheap and good psychological care in treatment support systems to control and reduce anxiety with least side effects.
{"title":"COMPARISON EFFECT OF LAVENDER AND CITRUS AURANTIUM AROMA ON ANXIETY IN FEMALE STUDENTS AT GOLESTAN UNIVERSITY OF MEDICAL SCIENCES","authors":"Bakhsha Fozieh, Y. Zahra, Aryaee Mohammad, Jafari Seyyed Yaquob, Derakhshanpoor Firoozeh","doi":"10.18869/ACADPUB.JBRMS.3.4.4","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBRMS.3.4.4","url":null,"abstract":"Introduction: Test anxiety is a common phenomenon and the problematic concern of the educational system. Scented essentials like lavender (angustifolia) oil and Citrus aurantium (orange flower) oil have positive impact on people's physical and mental condition and anxiety. This study was designed to compare and evaluate the effects of lavender essential oil aroma and Citrus aurantium essential oil aroma on test anxiety. Materials and methods: This double-blind clinical trial study was carried out on 80 female students from the Faculty of Paramedics Sciences, Gorgan city in 2013. Students were randomly and equally assigned to the two lavender or Citrus aurantium groups. All students smelled oil for a period of 60 seconds. To stay scents, some oil was rubbed on the candidates foreheads using an applicator. To evaluate the level of anxiety and stress before the intervention, Sarason Anxiety Test, and to measure the effect of essence after intervention, Visual Analogue Scale (VAS) questionnaire were used. Data were analyzed using SPSS16 software and the independent and paired T-tests. Results: The mean anxiety in students in lavender group dropped from (5.67±2.05) to (3.9± 1.82) and in Citrus aurantium group decreased from (5.25±2.06) to (3.97±2). This difference was statistically significant (P <0.001). The intervention had a significant effect on heart rate; however, had no effect on the blood pressure. Conclusion: According to the results, lavender and citrus aurantium scents had positive effects on students' test anxiety and can be used as a cheap and good psychological care in treatment support systems to control and reduce anxiety with least side effects.","PeriodicalId":15047,"journal":{"name":"Journal of Basic Research in Medical Sciences","volume":"3 1","pages":"4-11"},"PeriodicalIF":0.0,"publicationDate":"2016-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67672777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-01DOI: 10.18869/ACADPUB.JBRMS.3.4.12
Joghataei Mohammad Taghi, Bakhtiari Mehrdad, F. Farhid, Z. Mojgan, I. Mohammad, Moaieri Ardshir, Azizi Monireh
Introduction: Cell transplantation is one of the main strategies for spinal cord injury repair. As OECs of the olfactory mucosa can be obtained by simple biopsy in all individuals without affecting their smell sensation, OECs considered as a promising candidate for autologous transplantation in the nervous system injury, especially for spinal cord repair. Thereby in the current study OECs were cultured from olfactory mucosa of 7 days old rats' pups and their purity was examined by flow-cytometry after simultaneous double staining for p75 and GFAP markers. Materials and methods: 7 days old Wistar rats' pups were deeply anesthetized by ketamine / xylazine (60/6mg/Kg). Then the nasal cavity was opened sagittally and the olfactory mucosa was separated from posterior part of nasal septum and at last OECs were obtained from lamina properia of olfactory mucosa and were cultured. The cultured cells were simultaneously immunolabeled for p75 and GFAP markers and finally purity of cultured cells assessed by flow-cytometry. Results: cultured OECs demonstrated two different morphologies, a spindle shape Schwannlike and an astrocyte-like OECs with flat sheet-like morphology. In addition, simultaneous immunolabeling for p75 and GFAP markers of OECs exhibited OECs were positive for both markers at the same time. The flow-cytometry results displayed that 87.9±2.4% of cells were p75/ GFAP double positive cells,1.05±0.4 only p75 positive and 5.8±1.5% were single positive for GFAP. Conclusion: Purity of cultured OECs in our study is probably more than 87.9% by flowowing to p75+/S100+ and GFAP+/S100+ olfactory ensheathing cells were not counted. Thus the culture procedure of this study seems to be a good protocol for OECs purifying and cell therapy in CNS damages.
{"title":"Purity determining of cultured OECs from olfactory mucosa of rats' pups","authors":"Joghataei Mohammad Taghi, Bakhtiari Mehrdad, F. Farhid, Z. Mojgan, I. Mohammad, Moaieri Ardshir, Azizi Monireh","doi":"10.18869/ACADPUB.JBRMS.3.4.12","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBRMS.3.4.12","url":null,"abstract":"Introduction: Cell transplantation is one of the main strategies for spinal cord injury repair. As OECs of the olfactory mucosa can be obtained by simple biopsy in all individuals without affecting their smell sensation, OECs considered as a promising candidate for autologous transplantation in the nervous system injury, especially for spinal cord repair. Thereby in the current study OECs were cultured from olfactory mucosa of 7 days old rats' pups and their purity was examined by flow-cytometry after simultaneous double staining for p75 and GFAP markers. Materials and methods: 7 days old Wistar rats' pups were deeply anesthetized by ketamine / xylazine (60/6mg/Kg). Then the nasal cavity was opened sagittally and the olfactory mucosa was separated from posterior part of nasal septum and at last OECs were obtained from lamina properia of olfactory mucosa and were cultured. The cultured cells were simultaneously immunolabeled for p75 and GFAP markers and finally purity of cultured cells assessed by flow-cytometry. Results: cultured OECs demonstrated two different morphologies, a spindle shape Schwannlike and an astrocyte-like OECs with flat sheet-like morphology. In addition, simultaneous immunolabeling for p75 and GFAP markers of OECs exhibited OECs were positive for both markers at the same time. The flow-cytometry results displayed that 87.9±2.4% of cells were p75/ GFAP double positive cells,1.05±0.4 only p75 positive and 5.8±1.5% were single positive for GFAP. Conclusion: Purity of cultured OECs in our study is probably more than 87.9% by flowowing to p75+/S100+ and GFAP+/S100+ olfactory ensheathing cells were not counted. Thus the culture procedure of this study seems to be a good protocol for OECs purifying and cell therapy in CNS damages.","PeriodicalId":15047,"journal":{"name":"Journal of Basic Research in Medical Sciences","volume":"3 1","pages":"12-21"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67672660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-01DOI: 10.18869/ACADPUB.JBRMS.3.4.34
R. Kholoud, Abbasi Naser, H. Mohammadreza, Azizi Monireh, H. Azim, Abbaszadeh Hojjatallah, M. Ardeshir
Introduction: The aim of this work was to evaluate the effects of four different concentrations of Aloe vera extract on healing of second degree burns in male Wistar rats. Materials and methods: By an experimental study 42 male Wistar rats were divided into 7 equal groups. The burn injury was made on the back of all rats, according to standard methods. The burned areas in the group1: were left without any intervention, group 2: were treated topically with eucerin, group 3: were treated with SSD and groups 4-7 were covered with 0.5%, 1%, 1.5%, 2% Aloe vera extract in eucerin (basal cream) twice a day, respectively. 21 days later the rats were sacrificed and samples of burnt skin tissue were collected for histological examinations. The parameters were evaluated to be considered for review included the number of hair follicles, sebaceous glands of angiogenesis, acute inflammation (severe infiltration of neutrophils) and the formation of epithelial layers. Results: Diagram of healing levels and reduction rats of wounds' sizes in 3th week indicated that the former was reduced more significantly in groups 3, 6 and 7 than in groups 1 (P<0.005) and 2 (P<0.01). Histological findings showed that burn healing was significantly better in groups 6 and 7 than the groups 1 and 2 at the day 21. Conclusion: It could be concluded that concentration of 1.5% and 2% of Aloe vera extract have an effective role in the treatment of burn wound healing.
{"title":"Effect of different concentrations of Aloe vera leave's extract on the healing process of rat's second degree burn","authors":"R. Kholoud, Abbasi Naser, H. Mohammadreza, Azizi Monireh, H. Azim, Abbaszadeh Hojjatallah, M. Ardeshir","doi":"10.18869/ACADPUB.JBRMS.3.4.34","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBRMS.3.4.34","url":null,"abstract":"Introduction: The aim of this work was to evaluate the effects of four different concentrations of Aloe vera extract on healing of second degree burns in male Wistar rats. Materials and methods: By an experimental study 42 male Wistar rats were divided into 7 equal groups. The burn injury was made on the back of all rats, according to standard methods. The burned areas in the group1: were left without any intervention, group 2: were treated topically with eucerin, group 3: were treated with SSD and groups 4-7 were covered with 0.5%, 1%, 1.5%, 2% Aloe vera extract in eucerin (basal cream) twice a day, respectively. 21 days later the rats were sacrificed and samples of burnt skin tissue were collected for histological examinations. The parameters were evaluated to be considered for review included the number of hair follicles, sebaceous glands of angiogenesis, acute inflammation (severe infiltration of neutrophils) and the formation of epithelial layers. Results: Diagram of healing levels and reduction rats of wounds' sizes in 3th week indicated that the former was reduced more significantly in groups 3, 6 and 7 than in groups 1 (P<0.005) and 2 (P<0.01). Histological findings showed that burn healing was significantly better in groups 6 and 7 than the groups 1 and 2 at the day 21. Conclusion: It could be concluded that concentration of 1.5% and 2% of Aloe vera extract have an effective role in the treatment of burn wound healing.","PeriodicalId":15047,"journal":{"name":"Journal of Basic Research in Medical Sciences","volume":"3 1","pages":"34-39"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67672559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-01DOI: 10.18869/ACADPUB.JBRMS.3.4.28
Beig Mohammadi Hossein, M. Nahid, T. Ali, Allameh Abdolamir
Introduction: Serum C-reactive protein (CRP) is believed to be increased in metastatic urothelial cancer of the bladder. However, the changes depend on the stage and grade of the upper tract urothelial carcinoma (UTUC). This study aimed to compare low-range and high-range serum CRP and haptoglobin in new cases of UTUC. Materials and methods: Blood was collected from newly diagnosed patients with UTUC (n=43 patients; 39 male/4 female) and normal individuals (n=26; 24 male and 2 female) with no sign of infection or cancer. All the patients showed clinical symptoms of bladder cancer. Serum CRP and haptoglobin were estimated based on conventional methods. Results: Haematuria and polyuria were common symptoms in 65.12% of the patients suffering from UTUC. The serum level of HAPT in control and UTUC patients was 126±13 and 181±14.5 mg/dl respectively. No significant difference was observed in HAPT level in patients and controls. The HAPT was in the high-range level in 27% of controls and 30% of the patients. The average serum CRP level in patients and controls was 11.87±3.5 mg/l and 11.45±4.2 mg/l, respectively. Serum CRP was above 3.5 mg/l (>3.5 mg/l) in 46% of patients (20/43). The CRP level was significantly higher (P=0.023) in patients having CRP above 3.5 mg/l compared to respective controls. The UTUC patients were separated into two groups based on low-range ( 3.5 mg/l).Serum CRP was 3.5 mg/l. However, 46% of UTUC patients had serum CRP > 3.5 mg/l and 54% of UTUC patients had serum CRP < 3.5 mg/l. Conclusion: Although there was no difference in haptoglobin levels in patients and controls, but serum CRP was significantly increased in patients and it was associated with clinical symptoms of UTUC, suggesting that serum CRP can be considered as a complementary test for detection of low-grade UTUC.
{"title":"Diagnostic value of a combined C-reactive protein and haptoglobin tests in new cases of upper tract urothelial carcinoma","authors":"Beig Mohammadi Hossein, M. Nahid, T. Ali, Allameh Abdolamir","doi":"10.18869/ACADPUB.JBRMS.3.4.28","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBRMS.3.4.28","url":null,"abstract":"Introduction: Serum C-reactive protein (CRP) is believed to be increased in metastatic urothelial cancer of the bladder. However, the changes depend on the stage and grade of the upper tract urothelial carcinoma (UTUC). This study aimed to compare low-range and high-range serum CRP and haptoglobin in new cases of UTUC. Materials and methods: Blood was collected from newly diagnosed patients with UTUC (n=43 patients; 39 male/4 female) and normal individuals (n=26; 24 male and 2 female) with no sign of infection or cancer. All the patients showed clinical symptoms of bladder cancer. Serum CRP and haptoglobin were estimated based on conventional methods. Results: Haematuria and polyuria were common symptoms in 65.12% of the patients suffering from UTUC. The serum level of HAPT in control and UTUC patients was 126±13 and 181±14.5 mg/dl respectively. No significant difference was observed in HAPT level in patients and controls. The HAPT was in the high-range level in 27% of controls and 30% of the patients. The average serum CRP level in patients and controls was 11.87±3.5 mg/l and 11.45±4.2 mg/l, respectively. Serum CRP was above 3.5 mg/l (>3.5 mg/l) in 46% of patients (20/43). The CRP level was significantly higher (P=0.023) in patients having CRP above 3.5 mg/l compared to respective controls. The UTUC patients were separated into two groups based on low-range ( 3.5 mg/l).Serum CRP was 3.5 mg/l. However, 46% of UTUC patients had serum CRP > 3.5 mg/l and 54% of UTUC patients had serum CRP < 3.5 mg/l. Conclusion: Although there was no difference in haptoglobin levels in patients and controls, but serum CRP was significantly increased in patients and it was associated with clinical symptoms of UTUC, suggesting that serum CRP can be considered as a complementary test for detection of low-grade UTUC.","PeriodicalId":15047,"journal":{"name":"Journal of Basic Research in Medical Sciences","volume":"22 1","pages":"28-33"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67672823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-01DOI: 10.18869/ACADPUB.JBRMS.3.4.40
Afzalpour Mohammad Esmaiel, Y. Reza, A. Hossein, Ilbeigi. Saeed
Introduction: Diabetes mellitus (DM) is now seen as a worldwide epidemic disease with high prevalence. Exercise training (ET) is known to promote beneficial changes in diabetic patients. The aim of this study was to compare the impact of continuous and intermittent aerobic training on glucose-4 transporter protein (GLUT-4) levels and insulin sensitivity in diabetic rats. Materials and methods: This research was an experimental and interventional study. A number of 60 male rats weighing 180 to 310 grams and 13 weeks old were divided into six groups: healthy control, healthy continuous, healthy intermittent, diabetic control, diabetic continuous, and diabetic intermittent groups. The exercise protocol in both continuous and intermittent groups was aerobic training for six weeks which was conducted considering overload principle. The data were analyzed using one-way analysis of variance test in P< 0.05 level. Results: The results showed that despite the significant difference between insulin resistance and GLUT4 level among diabetic rats in different groups compared to control group, there was no significant difference between the impact of continuous and intermittent training on these indices (P=1.00). Conclusion: Through increasing the GLUT4 protein content, the continuous and intermittent training improved insulin resistance.
{"title":"THE COMPARISON OF CONTINUOUS AND INTERMITTENT TRAINING IMPACT ON GLUCOSE-4 TRANSPORTER PROTEIN LEVEL AND INSULIN SENSITIVITY IN DIABETIC RATS","authors":"Afzalpour Mohammad Esmaiel, Y. Reza, A. Hossein, Ilbeigi. Saeed","doi":"10.18869/ACADPUB.JBRMS.3.4.40","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBRMS.3.4.40","url":null,"abstract":"Introduction: Diabetes mellitus (DM) is now seen as a worldwide epidemic disease with high prevalence. Exercise training (ET) is known to promote beneficial changes in diabetic patients. The aim of this study was to compare the impact of continuous and intermittent aerobic training on glucose-4 transporter protein (GLUT-4) levels and insulin sensitivity in diabetic rats. Materials and methods: This research was an experimental and interventional study. A number of 60 male rats weighing 180 to 310 grams and 13 weeks old were divided into six groups: healthy control, healthy continuous, healthy intermittent, diabetic control, diabetic continuous, and diabetic intermittent groups. The exercise protocol in both continuous and intermittent groups was aerobic training for six weeks which was conducted considering overload principle. The data were analyzed using one-way analysis of variance test in P< 0.05 level. Results: The results showed that despite the significant difference between insulin resistance and GLUT4 level among diabetic rats in different groups compared to control group, there was no significant difference between the impact of continuous and intermittent training on these indices (P=1.00). Conclusion: Through increasing the GLUT4 protein content, the continuous and intermittent training improved insulin resistance.","PeriodicalId":15047,"journal":{"name":"Journal of Basic Research in Medical Sciences","volume":"3 1","pages":"40-48"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67672920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-01DOI: 10.18869/acadpub.jbrms.3.4.22
Ghanbari Afra Leila, Zaheri Azita
Introduction: Long-term complications of diabetes leads to physical and mental weakness and reduce their quality of life. One of the complications is the chronic wounds of extremities. Because of its outcome, patient’s adaptation can be reduced. The aim of this study was to compare depression between diabetic patients with and without foot wounds. Materials and methods: The comparative-descriptive study was performed on diabetic patients with and without foot wounds that admitted to the hospitals in Qom University of Medical Sciences in 2014. 100 patients with chronic wounds and 100 patients without the wounds was recruited by available sampling method for the study. We employed the “Demographic and clinical” and "Beck depression" questionnaires for gathering the data. The study data were analyzed by independent t and Chi-square tests using the SPSS (version 13) statistical software. Results: Mean and standard deviation of age in patient with and without chronic wound was 52.1±3.9 and 51.5±4.1 years, respectively. Depressive score of patient with and without chronic wound was also 25.6±9.5 and 8.7±2.1, respectively. Depression score of patient with underlying disease was higher than patients without underlying disease. The depression score rises with age. The depression scores were similar in both male and female gender. Conclusion: The depression in patient with chronic wounds was higher than patient without the wounds. Also, depression in patients with underlying disease and older age, rises.
{"title":"COMPARISON OF DEPRESSION IN DIABETIC PATIENTS WITH AND WITHOUT FOOT WOUND","authors":"Ghanbari Afra Leila, Zaheri Azita","doi":"10.18869/acadpub.jbrms.3.4.22","DOIUrl":"https://doi.org/10.18869/acadpub.jbrms.3.4.22","url":null,"abstract":"Introduction: Long-term complications of diabetes leads to physical and mental weakness \u0000and reduce their quality of life. One of the complications is the chronic wounds of \u0000extremities. Because of its outcome, patient’s adaptation can be reduced. The aim of this \u0000study was to compare depression between diabetic patients with and without foot wounds. \u0000Materials and methods: The comparative-descriptive study was performed on diabetic \u0000patients with and without foot wounds that admitted to the hospitals in Qom University of \u0000Medical Sciences in 2014. 100 patients with chronic wounds and 100 patients without the \u0000wounds was recruited by available sampling method for the study. We employed the \u0000“Demographic and clinical” and \"Beck depression\" questionnaires for gathering the data. The \u0000study data were analyzed by independent t and Chi-square tests using the SPSS (version 13) \u0000statistical software. \u0000Results: Mean and standard deviation of age in patient with and without chronic wound was \u000052.1±3.9 and 51.5±4.1 years, respectively. Depressive score of patient with and without \u0000chronic wound was also 25.6±9.5 and 8.7±2.1, respectively. Depression score of patient with \u0000underlying disease was higher than patients without underlying disease. The depression score \u0000rises with age. The depression scores were similar in both male and female gender. \u0000Conclusion: The depression in patient with chronic wounds was higher than patient without \u0000the wounds. Also, depression in patients with underlying disease and older age, rises.","PeriodicalId":15047,"journal":{"name":"Journal of Basic Research in Medical Sciences","volume":"3 1","pages":"22-27"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67672765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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