I. Medvedev, M. N. Komarov, V. Y. Karpov, A. Dorontsev, Xenia Alexandrovna Dorontseva, ElenaYurievna Sysoeva
At present, much attention is paid to various aspects concerning the impact of systematic muscular load on platelet parameters. In our study, we examined 107 healthy mature males. They were divided into 4 groups. In this study, we determined the mean platelet volume, their aggregation activity when introduced into plasma with 2.5, 5, and 10 μM ADP, and the amount of GP IIb-IIIa and GP Ib on the platelet surfaces. With an increase in daily muscle activity, the examined patients showed a weakening in the process of platelet aggregation in relation to all the applied concentrations of ADP, the content of adenosine phosphates in them, and the secretion of adenosine phosphates from them, the platelet level of actin and myosin, a decrease in platelets size and a reduction in the GP IIb-IIIa and GP Ib expressiveness. There was revealed the correlation between the volume of platelets, on the one hand, and platelet aggregation, the adenosine phosphates content in them and secretion from them, the level of actin and myosin self-assembly, and the density of GP IIb-IIIa and GP Ib receptors on platelet membranes, on the other hand, which, to a greater extent, manifested itself in the most physically active people. The changes in platelet parameters that occur in males of the second mature age if the distance traveled per day increases indicate the possibility of their optimization through a rational and controlled increase in physical activity within a day.
{"title":"The Effect of Regular Physical Activity on Platelet Activity in Men of Mature Age","authors":"I. Medvedev, M. N. Komarov, V. Y. Karpov, A. Dorontsev, Xenia Alexandrovna Dorontseva, ElenaYurievna Sysoeva","doi":"10.51847/59bnth85lh","DOIUrl":"https://doi.org/10.51847/59bnth85lh","url":null,"abstract":"At present, much attention is paid to various aspects concerning the impact of systematic muscular load on platelet parameters. In our study, we examined 107 healthy mature males. They were divided into 4 groups. In this study, we determined the mean platelet volume, their aggregation activity when introduced into plasma with 2.5, 5, and 10 μM ADP, and the amount of GP IIb-IIIa and GP Ib on the platelet surfaces. With an increase in daily muscle activity, the examined patients showed a weakening in the process of platelet aggregation in relation to all the applied concentrations of ADP, the content of adenosine phosphates in them, and the secretion of adenosine phosphates from them, the platelet level of actin and myosin, a decrease in platelets size and a reduction in the GP IIb-IIIa and GP Ib expressiveness. There was revealed the correlation between the volume of platelets, on the one hand, and platelet aggregation, the adenosine phosphates content in them and secretion from them, the level of actin and myosin self-assembly, and the density of GP IIb-IIIa and GP Ib receptors on platelet membranes, on the other hand, which, to a greater extent, manifested itself in the most physically active people. The changes in platelet parameters that occur in males of the second mature age if the distance traveled per day increases indicate the possibility of their optimization through a rational and controlled increase in physical activity within a day.","PeriodicalId":15062,"journal":{"name":"Journal of Biochemical Technology","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70812838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Biologically Active Substances in Cichorium on Biochemical Changes in Obese Rats","authors":"Lobna Saad Mohammed Abd Elmeged, M. S. Alzahrani","doi":"10.51847/bn6mhuzxbb","DOIUrl":"https://doi.org/10.51847/bn6mhuzxbb","url":null,"abstract":"","PeriodicalId":15062,"journal":{"name":"Journal of Biochemical Technology","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70816183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. M. Muddathir, E. I. Abdallah, W. O. Elradi, Mohammed Elmobarak Elbasheir, R. Abdelgadir, H. Waggiallah
{"title":"Prevalence of HDNF due to ABO, Rh (D) and Other Blood Groups among Newborns, Sudan","authors":"A. M. Muddathir, E. I. Abdallah, W. O. Elradi, Mohammed Elmobarak Elbasheir, R. Abdelgadir, H. Waggiallah","doi":"10.51847/qvdq4xmlif","DOIUrl":"https://doi.org/10.51847/qvdq4xmlif","url":null,"abstract":"","PeriodicalId":15062,"journal":{"name":"Journal of Biochemical Technology","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70831949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Review of PHB Production by Cyanobacteria and Its Applications","authors":"A. Ranganadhareddy, RinkuPolachirakkal Varghese","doi":"10.51847/ty7wnh5ia3","DOIUrl":"https://doi.org/10.51847/ty7wnh5ia3","url":null,"abstract":"","PeriodicalId":15062,"journal":{"name":"Journal of Biochemical Technology","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70835366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Review on Production of Polyhydroxyalkanoates in Microorganisms","authors":"A. Ranganadhareddy","doi":"10.51847/uo3eebmgid","DOIUrl":"https://doi.org/10.51847/uo3eebmgid","url":null,"abstract":"","PeriodicalId":15062,"journal":{"name":"Journal of Biochemical Technology","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70836074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natalia Georgievna Salbieva, A. A. Cheldieva, E. G. Plieva, Linda Aslanbekovna Yusupova, Dmitry Alexandrovich Dunets, Rayana Aslambekovna Shakhbieva
This article discusses the complexities and various aspects related to the treatment of pregnant women with COVID-19. The experience of Chinese doctors who were the first to face this problem is considered, and a new method of treating the disease using the drug Baricitinib is also considered. Baricitinib is an anti-inflammatory drug, a representative of the Janus kinase class, used in the treatment of rheumatoid arthritis. It blocks intracellular signaling pathways, which leads to the regulation of the synthesis of interleukins 2, 6, 10, and interferon-gamma. The drug is licensed for the treatment of rheumatoid arthritis, has good efficacy and safety indicators. Attention was paid to the doses and modes of use of baricitinib. The article discusses a study conducted by Chinese doctors. The study involved 34 infected pregnant women, of whom half were offered standard treatment and the other half standard treatment with baricitinib. In order to have a complete picture that allows us to conclude that this method of treatment is ineffective or effective, it is necessary to continue monitoring patients who took baracitinib in the treatment of COVID-19.
{"title":"Evaluation of the Treatment of Pregnant Women with COVID-19 Using the Drug Baricitinib","authors":"Natalia Georgievna Salbieva, A. A. Cheldieva, E. G. Plieva, Linda Aslanbekovna Yusupova, Dmitry Alexandrovich Dunets, Rayana Aslambekovna Shakhbieva","doi":"10.51847/zakeejbxjb","DOIUrl":"https://doi.org/10.51847/zakeejbxjb","url":null,"abstract":"This article discusses the complexities and various aspects related to the treatment of pregnant women with COVID-19. The experience of Chinese doctors who were the first to face this problem is considered, and a new method of treating the disease using the drug Baricitinib is also considered. Baricitinib is an anti-inflammatory drug, a representative of the Janus kinase class, used in the treatment of rheumatoid arthritis. It blocks intracellular signaling pathways, which leads to the regulation of the synthesis of interleukins 2, 6, 10, and interferon-gamma. The drug is licensed for the treatment of rheumatoid arthritis, has good efficacy and safety indicators. Attention was paid to the doses and modes of use of baricitinib. The article discusses a study conducted by Chinese doctors. The study involved 34 infected pregnant women, of whom half were offered standard treatment and the other half standard treatment with baricitinib. In order to have a complete picture that allows us to conclude that this method of treatment is ineffective or effective, it is necessary to continue monitoring patients who took baracitinib in the treatment of COVID-19.","PeriodicalId":15062,"journal":{"name":"Journal of Biochemical Technology","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70842029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Kachenkova, Yulia V. Zbrueva, E. Tkacheva, D. Pravdov, M. V. Eremin, A. Romanova, V. Sharagin, Elmira Shamilevna Petina, A. L. Yurchenko
{"title":"Hematological Indicators of Students Who Started Races","authors":"E. Kachenkova, Yulia V. Zbrueva, E. Tkacheva, D. Pravdov, M. V. Eremin, A. Romanova, V. Sharagin, Elmira Shamilevna Petina, A. L. Yurchenko","doi":"10.51847/noiozxvk5j","DOIUrl":"https://doi.org/10.51847/noiozxvk5j","url":null,"abstract":"","PeriodicalId":15062,"journal":{"name":"Journal of Biochemical Technology","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70827775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Vladimirovna Kryuchkova, Runa Usmanovna Tunguzbieva, Kumira Sultanovna Tokaeva, Adam Aiupovich Isaev, Layla Ruslanovna Elmaeva, V. Mikhailenko
{"title":"Collagen Hydrolysates in the Prevention and Treatment of Arthritis","authors":"Anna Vladimirovna Kryuchkova, Runa Usmanovna Tunguzbieva, Kumira Sultanovna Tokaeva, Adam Aiupovich Isaev, Layla Ruslanovna Elmaeva, V. Mikhailenko","doi":"10.51847/3swkk0nmnp","DOIUrl":"https://doi.org/10.51847/3swkk0nmnp","url":null,"abstract":"","PeriodicalId":15062,"journal":{"name":"Journal of Biochemical Technology","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antioxidant and Antidiabetic Effect of Biosynthesis Zinc Nanoparticles by Using Polyherbal Aqueous Extract in Wistar Rats","authors":"Derouiche Samir, Benmoussa Ouissam, Djouadi Anfal","doi":"10.51847/h9wwu5frna","DOIUrl":"https://doi.org/10.51847/h9wwu5frna","url":null,"abstract":"","PeriodicalId":15062,"journal":{"name":"Journal of Biochemical Technology","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70822090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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