Journal of Autism and Developmental Disorders最新文献

This longitudinal study investigated the predictive value of initial level and growth rate of joint attention and play from 10 to 24 months for language abilities of 24-month-old toddlers at elevated likelihood (EL) for autism. (Semi-)structured assessments were used to measure all variables at different timepoints prospectively in younger siblings of children with autism (siblings, n = 48) and children born before 30 gestational weeks (preterms, n = 49). A positive association was found between initial level of play at 10 months and expressive language at 24 months in siblings, but not in preterms. We did not find an association between initial level of play and receptive language. Growth rate of play and initial level and growth rate of joint attention were not related to language abilities in siblings and preterms. Our results indicate that play and expressive language are interrelated, and early play behaviour may contribute to later language. As this association was absent in preterms, they may follow qualitatively different developmental processes. Moreover, future research including different EL-groups is needed to clarify these differential associations. In contrast to previous studies, no association between early joint attention and later language was found. These inconsistent findings warrant further exploration and highlight the importance of exploring alternative aspects of early development, for instance non-social factors, to expand our understanding of language acquisition.

The current study examined the association between interpersonal social goals (i.e., agentic and communal goals) and bullying behaviour for autistic adolescents (n = 108, M_age = 15.25 years, SD = 1.65) and neurotypical adolescents (n = 592, M_age = 13 years, SD = 0.5). Bullying behaviour was assessed using both self- and peer-reported measures. Agentic and communal social goals were assessed using the child version of the Interpersonal Goal Index. Measurement properties of the Interpersonal Goal Index were first examined, and some features were found to differ across autistic and neurotypical adolescents. Bullying behaviour was associated with agentic goals for neurotypical adolescents whereas communal goals were associated with bullying for autistic adolescents, suggesting a mismatch between social goals and social behaviours for this group. This insight suggests that the dynamics of bullying behaviour differ between neurotypical and autistic adolescents, and highlight the need for the development of autistic-led assessment and support for bullying.

This systematic review and meta-analysis aimed to identify and evaluate the quality of randomised controlled trials (RCTs), assessing the efficacy of Social Skills Group Programs (SSGPs) for primary and secondary school aged autistic children and adolescents exploring the influence of informant, setting characteristics and teaching strategies as moderating factors for social outcomes. A search of the electronic databases of Medline, ProQuest, CINAHL, Scopus, and Web of Sciences electronic databases was conducted for the period January 1, 2013 until December 31, 2023 for peer-reviewed RCT studies published in English, evaluating the efficacy of SSGPs for school-aged autistic children and adolescents (6-18 years). Included studies were assessed for methodological quality and efficacy using random effect meta-analysis. Informant analysis and moderator analyses were also conducted investigating the influence of informant, setting characteristics and teaching strategy utilised in the SSGPs on the participants social outcomes. Sixty-five studies were included in the systematic review with 49 studies included in the meta-analysis. Although most studies had strong or good methodological quality, a high possibility of publication bias was detected in the meta-analysis. After statistical adjustments for publication bias were made, findings revealed that SSGPs had no effect on the overall outcomes assessed by included studies on school-aged autistic children and adolescents. However, informant analysis revealed small effects reported by self-report, parent-proxy and researchers. Teaching strategies and setting characteristics were not significant moderators for the efficacy of SSGPs on the social outcomes of autistic children and adolescents. This review highlights the need for improvements in measurement frameworks for assessing social skills in autistic children and adolescents.

Detection and monitoring of emotional and behavior problems is a critical part of clinical care for children diagnosed with autism spectrum disorder (ASD) and other neurodevelopmental disorders (NDDs), as well as a common focus of research. The Child Behavior Checklist (CBCL) is a well-established caregiver-report instrument that is used for screening and monitoring of emotional and behavior problems in individuals diagnosed with ASD and NDDs. However, it has over 100 items and can be time-consuming to complete. The Brief Problem Monitor Parent Report (BPM-P; Achenbach et al. 2011) includes a subset of the CBCL items and is intended for monitoring emotional and behavior problems. However, its validity has not been examined in ASD or NDD samples. Data from 302 children ages 6-18 years whose caregivers had completed the CBCL were drawn from a clinical research databank. Confirmatory factor analysis of the BPM-P three-factor structure had mixed findings. All BPM-P scales had acceptable internal consistency, and agreement between the BPM-P cutoffs and the corresponding CBCL clinical cutoffs was acceptable for the broad problem scales. The Attention scale demonstrated high sensitivity, but poor specificity. Results provide initial evidence that the BPM-P may be a useful alternative to the CBCL, producing comparable information for broad problems, while requiring much less time from caregivers. BPM-P users may want to consider the Attention scale separately due to poor specificity compared to the CBCL. These results will need to be replicated using larger samples and independent administrations of the BPM-P and the CBCL.

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with altered brain activity. However, little is known about the integrated temporospatial variation of dynamic spontaneous brain activity in ASD. In the present study, resting-state functional magnetic resonance imaging data were analyzed for 105 ASD and 102 demographically-matched typically developmental controls (TC) children obtained from the Autism Brain Imaging Data Exchange database. Using the sliding-window approach, temporal, spatial, and temporospatial variability of dynamic amplitude of low-frequency fluctuation (tvALFF, svALFF, and tsvALFF) were calculated for each participant. Group-comparisons were further performed at global, network, and brain region levels to quantify differences between ASD and TC groups. The relationship between temporospatial dynamic amplitude of low-frequency fluctuation variation alterations and clinical symptoms of ASD was finally explored by a support vector regression model. Relative to TC, we found enhanced tvALFF in visual network (Vis), somatomotor network (SMT), and salience/ventral attention network (SVA) of ASD, and weakened tvALFF in dorsal attention network (DAN) of ASD. Besides, ASD showed decreased svALFF in Vis, SVA, and limbic network (Limbic), and increased svALFF in DAN and default mode network (DMN). Elevated tsvALFF was found in the Vis, SMT, and DMN of ASD. More importantly, the altered tsvALFF from the DMN can predict the symptom severity of ASD. These findings demonstrate altered temporospatial dynamics of the spontaneous brain activity in ASD and provide novel insights into the neural mechanism underlying ASD.

This randomized controlled trial examined the effectiveness of an online autism training intervention in reducing stigma toward autistic individuals. Participants were 208 Korean undergraduate students who were blinded to group allocation, with 106 assigned to the autism training and 102 assigned to a control intervention. All participants completed an online Qualtrics survey that included a pre-test survey (perceived similarity to different minority groups), the training, and a post-test survey (perceived similarity, stigma toward autistic people, knowledge about autism, confidence in their knowledge, and open-responses question asking for descriptions of autism). We conducted independent sample t tests and a mixed-effects model to examine group-level differences, and a reliable change index (RCI) analysis to examine individual changes in the perceived similarity score. The responses to the open-ended questions were analyzed using qualitative content analysis. Results revealed that the experimental group reported reduced stigma toward autistic individuals, increased perceived similarity with autistic individuals, and increased confidence in their autism knowledge and demonstrated increased knowledge about autism compared to the control group. At the individual level, the RCI analysis indicated that the training was effective for a notable subset of participants (25%). At post-test, the experimental group recognized the strengths of autistic people and described autistic individuals as "people like us," while many in the control group mentioned misconceptions about autism. Future research should employ more robust intervention designs and tailor materials for diverse target populations, including administrators, to foster systemic destigmatization.

Purpose: There is a dearth of information about patients with autism spectrum disorder (ASD) or intellectual disability (ID) who seek emergency psychiatric care. Given this backdrop, this retrospective study aims to explore clinical, demographic, and disposition-related information about this patient population over a 10-year period.

Methods: This study includes individuals with ASD or ID (n = 1461) and had presented to a psychiatric emergency department between 2012 and 2021. Data were extracted using a structured chart review methodology, and included demographic, clinical and visit information. Bivariate and multivariate logistic regressions were estimated to explore associations between key variables and dispositions of interest.

Results: Sample was predominantly White (77.21%), adolescent (mean age ± SD = 15.5 ± 4.3) and male (72.76%). The most common reason for their presentation was aggression towards others (36.39%). 28.27% of patients were psychiatrically hospitalized but 30% of those who needed hospitalization were discharged due to lack of inpatient bed availability.

Conclusion: This study adds to the limited literature about individuals with ASD or ID seeking emergency care. The results indicate a highly acute patient population with aggression, suicidal thoughts, and self-injurious behaviors who are frequently prescribed psychotropic medications and face barriers to accessing higher levels of care.

Parents of children with autism often experience a wide range of emotions in their daily lives. However, previous research has primarily focused on average levels of emotional challenges, neglecting the significance of daily emotion dynamics that may underlie parental psychological functioning. This study adopted a dynamic network approach to examine the strength of temporal connections within and between various emotions-referred to as emotion network density-and further explore its impacts on parental psychological distress. Participants included 76 Chinese parents (M = 36.36 years, SD = 3.95 years; 58 mothers) of children with autism. Parents reported their psychological distress at baseline and then completed measures of daily emotions over a 14-day period. The densities of overall, positive, and negative emotion networks were estimated using the Multilevel Vector Auto-Regression model. The results indicated that higher densities of the overall and negative emotion networks were associated with increased stress, anxiety, and depressive symptoms in parents. Further analysis of network components showed that the in-strength of fear and guilt (i.e., their likelihood of being affected by other emotions) and the out-strength of anger and guilt (i.e., their capacity to influence other emotions) were positively related to parental psychological distress. However, neither the overall density of the positive emotion network nor its specific components showed a significant relationship with parental psychological distress. These findings highlight the importance of considering the daily dynamics of emotions, particularly negative emotions, from a network perspective to better understand the development of psychological distress in parents of children with autism.