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A Network Approach to Understanding the Role of Executive Functioning and Alpha Oscillations in Inattention and Hyperactivity-Impulsivity Symptoms of ADHD. 通过网络方法了解执行功能和阿尔法振荡在注意力不集中和多动症的过度活跃-冲动症状中的作用。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-08-01 Epub Date: 2024-05-26 DOI: 10.1177/10870547241253999
Juan Diego Vera, René Freichel, Giorgia Michelini, Sandra K Loo, Agatha Lenartowicz

Objective: ADHD is a prevalent neurodevelopmental disorder characterized by symptoms of inattention and hyperactivity-impulsivity. Impairments in executive functioning (EF) are central to models of ADHD, while alpha-band spectral power event-related decreases (ERD) have emerged as a putative electroencephalography (EEG) biomarker of EF in ADHD. Little is known about the roles of EF and alpha ERD and their interactions with symptoms of ADHD.

Method: We estimated network models of ADHD symptoms and integrated alpha ERD measures into the symptom network.

Results: EF emerges as a bridge network node connecting alpha ERD and the hyperactivity/impulsivity and inattention symptoms. We found that EF most closely relates to a subset of symptoms, namely the motoric symptoms, "seat" (difficulty staying seated), and "runs" (running or climbing excessively).

Conclusions: EF functions as a bridge node connecting alpha ERD and the ADHD symptom network. Motoric-type symptoms and EF deficits may constitute important nodes in the interplay between behavior/symptoms, cognition, and neurophysiological markers of ADHD.

目的:多动症(ADHD)是一种以注意力不集中和多动冲动为特征的神经发育障碍。执行功能(EF)受损是多动症模型的核心,而阿尔法波段频谱功率事件相关下降(ERD)已成为多动症EF的潜在脑电图(EEG)生物标志物。人们对EF和阿尔法ERD的作用及其与ADHD症状的相互作用知之甚少:方法:我们估计了多动症症状的网络模型,并将阿尔法ERD测量值整合到症状网络中:结果:EF是连接α ERD与多动/冲动和注意力不集中症状的桥梁网络节点。我们发现,EF 与运动症状 "坐"(难以保持坐姿)和 "跑"(过度奔跑或攀爬)中的一个子集关系最为密切:结论:EF是连接α ERD和ADHD症状网络的桥梁节点。运动型症状和心肺功能缺陷可能是多动症的行为/症状、认知和神经生理指标之间相互作用的重要节点。
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引用次数: 0
Highly Involved Parenting of Adolescents With ADHD: Examination of the Psychometric Properties of a Measure of "Helicopter Parenting". 对患有多动症的青少年的高投入式教养:研究 "直升机式教养 "测量法的心理测量特性。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-08-01 Epub Date: 2024-06-10 DOI: 10.1177/10870547241258879
Tessa N Botkin, Kelsey Wiggs, Heidi L Kipp, Rachel A Lindstrom, Heather M Joseph, David J Kolko, Sarah L Pedersen, Brooke S G Molina

Objective: The concept of the "helicopter parent" was popularized in the 2000s and 2010s by Western culture, and it has recently begun to be examined by researchers to describe parental over-involvement and intrusive behavior that impedes transition into adulthood. Research has yet to investigate the viability of this construct for adolescents when parenting is needed to facilitate the development of autonomy. The present study examined the psychometric structure of a modified "helicopter parenting" measure adapted for use in a sample with increased likelihood of highly involved parenting: adolescents with ADHD.

Methods: Adolescents (n = 333; age 13-18 years; 25% female) and their parents (n = 341, 91% female) completed a survey for a study on provider training in stimulant diversion prevention in 2016 and 2017. We modified a previously validated measure of "helicopter parenting" for young adults. Other previously established parenting measures were included. We conducted principal component analysis for both informants' reports of the modified measure. We examined associations between the components and informants' demographic characteristics and parenting measures to begin to examine convergent and discriminant validity.

Results: Two components were identified for adolescent and parent reports and labeled parental Intervention and Day-to-day Monitoring and Planning. These components were differentially associated with demographic characteristics and other measures of parenting. For example, across reporters, parents exhibited less Day-to-Day Monitoring and Planning for older adolescents. Racially/ethnically minoritized parents and male adolescents reported more Intervention parenting. Modest-sized statistically significant associations were found between these indicators of highly involved parenting and the other measures of parenting.

Conclusion: Findings provide initial evidence of construct validity. Future work with more heterogeneous samples should examine if this measure captures adaptive parenting, or behaviors that interfere with developing independence, for adolescents with ADHD and neurotypically developing adolescents.

目的:直升机父母 "这一概念在 2000 和 2010 年代的西方文化中流行开来,最近研究人员开始对这一概念进行研究,以描述父母的过度介入和干涉行为,这些行为阻碍了青少年向成年期的过渡。当青少年需要父母的养育来促进其自主性的发展时,研究人员尚未对这一概念在青少年中的可行性进行调查。本研究对经过修改的 "直升机养育 "测量方法的心理测量结构进行了研究,该测量方法适用于高介入养育可能性增加的样本:患有多动症的青少年:青少年(n = 333;年龄13-18岁;25%为女性)及其父母(n = 341,91%为女性)在2016年和2017年完成了一项调查,该调查是为一项关于提供者在兴奋剂转用预防方面的培训的研究而进行的。我们修改了之前经过验证的针对青少年的 "直升机养育 "测量方法。我们还纳入了其他以前建立的养育措施。我们对两个信息提供者对修改后的测量方法的报告进行了主成分分析。我们研究了这些成分与信息提供者的人口统计学特征和养育措施之间的关联,从而开始研究聚合效度和区分效度:在青少年和家长的报告中发现了两个组成部分,分别称为 "家长干预 "和 "日常监督与规划"。这些要素与人口统计学特征和其他养育子女的测量方法存在不同的关联。例如,在不同的报告中,家长对年龄较大的青少年的日常监控和规划较少。少数种族/族裔家长和男性青少年则报告了更多的 "干预 "养育方式。在这些高度参与型养育指标与其他养育测量指标之间发现了中等规模的统计学意义上的关联:结论:研究结果提供了构建有效性的初步证据。未来的研究工作应使用更多的异质性样本,研究该指标是否能反映多动症青少年和神经发育正常青少年的适应性养育行为,或影响其独立性发展的行为。
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引用次数: 0
Parental Report of Remission in ADHD: Results From a Community-Based, Nationally Representative Sample. 家长对多动症缓解情况的报告:以社区为基础、具有全国代表性的抽样调查结果。
IF 3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-07-01 Epub Date: 2024-01-03 DOI: 10.1177/10870547231219005
Lucy Barnard-Brak

Objective: Various studies have examined rates of remission in ADHD with mixed results.

Method: Survival curve analyses were performed on a community-based sample.

Results: The results of the current study appear to support the contemporary literature that rates of remission in ADHD are lower than have been found in many earlier studies. The current study also reports a mean age of remission in ADHD of around 14 years old, which has not been previously reported via survival curve analyses. Additionally, the results of the current study found several variables to be significantly associated with remission in ADHD which included: the presence of comorbid disorder; lower symptoms of ADHD; sex of the child (being female); and the receipt of behavioral treatment.

Conclusion: Implications and limitations are discussed as related to these findings.

研究目的多项研究对多动症的缓解率进行了调查,结果不一:方法:对社区样本进行生存曲线分析:本研究的结果似乎支持当代文献的观点,即多动症的缓解率低于许多早期研究的结果。本次研究还发现,多动症患者的平均缓解年龄约为 14 岁,而此前的生存曲线分析中从未发现过这一数据。此外,本研究还发现了与多动症缓解显著相关的几个变量,其中包括:存在合并症;多动症症状较轻;儿童性别(女性);接受行为治疗:结论:讨论了这些研究结果的意义和局限性。
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引用次数: 0
Cognitive Disengagement Syndrome in Mothers of Children With Attention-Deficit/Hyperactivity Disorder. 注意力缺陷/多动症儿童母亲的认知分离综合症。
IF 3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-07-01 Epub Date: 2024-02-07 DOI: 10.1177/10870547231224089
Yavuz Yılmaz, Ayla Uzun Cicek

Objective: To examine the cognitive disengagement syndrome (CDS) symptoms of mothers of children with attention-deficit/hyperactivity disorder (ADHD).

Method: The participants consisted of 223 mothers of children with ADHD, and data were collected using the Structured Clinical Interview for DSM-5 Disorders-Clinician Version (SCID-5-CV), the Stroop Test (ST), the Barkley Adult SCT Scale (CDS), and the Adult ADHD Self-Report Scale (ASRS).

Results: The participants were divided into four groups based on psychopathology: the group without any psychiatric disorder, the group with only ADHD, the group with a psychiatric disorder other than ADHD, and the group with another psychiatric disorder along with ADHD. The group with any psychiatric disorder along with ADHD had the highest CDS scores, while the group without any psychopathology had the lowest CDS scores.

Conclusion: CDS seems to be a construct associated with both ADHD and other internalizing disorders. Further studies are needed to shed more light on these relationships.

目的:研究注意力缺陷/多动症(ADHD)儿童母亲的认知分离综合征(CDS)症状:研究患有注意力缺陷/多动障碍(ADHD)儿童的母亲的认知分离综合征(CDS)症状:参与者包括 223 位注意力缺陷/多动症儿童的母亲,使用 DSM-5 疾病结构化临床访谈-医师版(SCID-5-CV)、Stroop 测试(ST)、巴克利成人 SCT 量表(CDS)和成人注意力缺陷/多动症自评量表(ASRS)收集数据:根据精神病理学将参与者分为四组:无任何精神障碍组、仅患有多动症组、患有多动症以外的精神障碍组和患有多动症的其他精神障碍组。有任何精神障碍并伴有多动症的一组的 CDS 得分最高,而没有任何精神病理学的一组的 CDS 得分最低:结论:CDS似乎是一种与ADHD和其他内化障碍相关的结构。结论:CDS 似乎是一种与多动症和其他内化障碍都有关联的结构,需要进一步的研究来揭示这些关系。
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引用次数: 0
Prevalence, Correlates, and Comorbidities Among Young Adults Who Screened Positive for ADHD in South Korea During the COVID-19 Pandemic. 在 COVID-19 大流行期间,韩国多动症筛查呈阳性的年轻人中的患病率、相关性和合并症。
IF 3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-07-01 Epub Date: 2024-05-31 DOI: 10.1177/10870547241253151
SongEun Park, Subin Park

Objective: This study examined the prevalence, associated factors, and psychiatric comorbidities of adult ADHD during the COVID-19 pandemic by analyzing nationally representative data.

Methods: Among the 5,511 respondents of the 2021 National Mental Health Survey, South Korea, 2,764 (18-49 years) were selected. The Korean versions of the Adult ADHD Self-Report Scale, Composite International Diagnostic Interview, and Structured Clinical Interview for Internet Gaming Disorder were used as diagnostic assessments.

Results: The 6-month prevalence of positive screens for adult ADHD was 3.1%. In individuals aged 18 to 29 years exhibiting adult ADHD symptoms, high prevalence rates of alcohol use, depression, and Internet gaming disorders were observed in the last 12 months. Adults who screened positive for ADHD reported significantly lower life satisfaction and resilience, and higher loneliness and social isolation (vs. non-ADHD group).

Conclusion: Adult ADHD symptoms significantly influenced mental well-being, highlighting the need for an appropriate treatment/prevention system, particularly for individuals aged 18 to 29 years.

目的:本研究通过分析具有全国代表性的数据,研究了 COVID-19 大流行期间成人多动症的患病率、相关因素和精神疾病合并症:本研究通过分析具有全国代表性的数据,研究了COVID-19大流行期间成人多动症的患病率、相关因素和精神疾病合并症:在韩国 2021 年全国心理健康调查的 5,511 名受访者中,选取了 2,764 名受访者(18-49 岁)。采用韩国版成人多动症自评量表、国际综合诊断访谈和网络游戏障碍结构化临床访谈进行诊断评估:成人多动症 6 个月阳性筛查率为 3.1%。在18至29岁表现出成人多动症症状的人群中,过去12个月中酗酒、抑郁和网络游戏障碍的患病率较高。与非多动症组相比,多动症筛查呈阳性的成人的生活满意度和复原力明显较低,孤独感和社会隔离感较高:结论:成人多动症症状会严重影响心理健康,因此需要适当的治疗/预防系统,尤其是针对 18 至 29 岁的人群。
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引用次数: 0
Emotion Regulation and Organizational Skills in Children With ADHD Symptoms Are Associated With Behavioral Parent Training Adherence. 多动症儿童的情绪调节和组织能力与家长坚持行为训练有关。
IF 3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-07-01 Epub Date: 2024-05-10 DOI: 10.1177/10870547241251725
Elizabeth J Hawkey, Aya I Williams, Sara Chung, Elizabeth B Owens, Linda J Pfiffner

Objective: Behavioral parent training (BPT) is a well-established treatment for ADHD; however, treatment response is variable. Consistency in parent skill use during BPT is known to influence child outcomes post-treatment, while less research has focused on specific child factors that may be impacting parent skill utilization during treatment. The current study examined associations between child organizational skills and emotion dysregulation (ED) with parent treatment adherence during BPT and post-treatment child impairment.

Method: Parents of 72 children (Mage = 8.31) with ADHD symptoms and impairment participated in BPT which was embedded in a 12-week, multicomponent, school-based intervention for children delivered by school mental health clinicians. Outcomes included parent treatment adherence and child improvements in global impairment post-treatment.

Results: Greater pre-treatment child organizational problems were associated with less parent treatment adherence regardless of ADHD symptom severity. Worse pre-treatment child ED was associated with more impairment post-treatment regardless of ADHD symptom severity whereas the effects of child ED on parent treatment adherence were moderated by child ADHD symptom severity.

Conclusion: The current study suggests that pre-treatment child ED and organizational difficulties impact parent treatment adherence to behavioral interventions targeting ADHD symptoms, potentially in unique ways, and should be considered in future BPT treatment studies.

目的:父母行为训练(BPT)是一种行之有效的多动症治疗方法,但治疗效果却不尽相同。众所周知,在 BPT 治疗过程中,家长技能使用的一致性会影响儿童治疗后的结果,但较少研究关注可能影响家长在治疗过程中使用技能的特定儿童因素。本研究探讨了儿童组织技能和情绪失调(ED)与家长在 BPT 治疗期间坚持治疗以及治疗后儿童损伤之间的关系:72名有多动症症状和障碍的儿童(年龄=8.31岁)的家长参加了BPT,BPT被纳入由学校心理健康临床医生提供的为期12周、多成分、基于学校的儿童干预中。研究结果包括家长对治疗的依从性以及治疗后儿童全面障碍的改善情况:结果:无论多动症症状的严重程度如何,治疗前儿童组织问题越严重,家长坚持治疗的程度就越低。无论儿童多动症症状的严重程度如何,治疗前儿童组织问题较严重与治疗后儿童功能受损程度较高有关,而儿童组织问题对家长治疗依从性的影响受儿童多动症症状严重程度的调节:本研究表明,治疗前的儿童ED和组织困难会影响家长坚持针对ADHD症状的行为干预治疗,可能会以独特的方式产生影响,在未来的BPT治疗研究中应加以考虑。
{"title":"Emotion Regulation and Organizational Skills in Children With ADHD Symptoms Are Associated With Behavioral Parent Training Adherence.","authors":"Elizabeth J Hawkey, Aya I Williams, Sara Chung, Elizabeth B Owens, Linda J Pfiffner","doi":"10.1177/10870547241251725","DOIUrl":"10.1177/10870547241251725","url":null,"abstract":"<p><strong>Objective: </strong>Behavioral parent training (BPT) is a well-established treatment for ADHD; however, treatment response is variable. Consistency in parent skill use during BPT is known to influence child outcomes post-treatment, while less research has focused on specific child factors that may be impacting parent skill utilization during treatment. The current study examined associations between child organizational skills and emotion dysregulation (ED) with parent treatment adherence during BPT and post-treatment child impairment.</p><p><strong>Method: </strong>Parents of 72 children (<i>M</i><sub>age</sub> = 8.31) with ADHD symptoms and impairment participated in BPT which was embedded in a 12-week, multicomponent, school-based intervention for children delivered by school mental health clinicians. Outcomes included parent treatment adherence and child improvements in global impairment post-treatment.</p><p><strong>Results: </strong>Greater pre-treatment child organizational problems were associated with <i>less</i> parent treatment adherence regardless of ADHD symptom severity. Worse pre-treatment child ED was associated with <i>more</i> impairment post-treatment regardless of ADHD symptom severity whereas the effects of child ED on parent treatment adherence were moderated by child ADHD symptom severity.</p><p><strong>Conclusion: </strong>The current study suggests that pre-treatment child ED and organizational difficulties impact parent treatment adherence to behavioral interventions targeting ADHD symptoms, potentially in unique ways, and should be considered in future BPT treatment studies.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"1320-1330"},"PeriodicalIF":3.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140896065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Qualitative Analysis of Perspectives on Self-directed Violence in a Prospective Longitudinal Study of Young Women With and Without Childhood ADHD. 在一项针对患有和未患有儿童多动症的年轻女性的前瞻性纵向研究中,对自导自演的暴力行为的观点进行了定性分析。
IF 3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-07-01 Epub Date: 2024-01-31 DOI: 10.1177/10870547231221729
Shaikh I Ahmad, Stephen P Hinshaw

Objective: Non-suicidal self-directed violence (NSSDV) is a significant and growing youth public health crisis. Girls with ADHD are at increased risk of engaging in NSSDV, yet qualitative studies with this population-to better understand manifestations, motivations, and developmental course-are lacking.

Method: We conducted semi-structured, qualitative interviews with a sub-sample of 57 young women (32 with childhood ADHD, 25 neurotypical comparisons; mean age of 27 years, part of a larger prospective longitudinal study) regarding histories and manifestations of NSSDV.

Results: Inductive and deductive analysis revealed several key themes, including self-perceived reasons for engaging in NSSDV (affect regulation, attention seeking, self-punishment, asserting control), impulsivity, secretiveness, and in some cases motivations for desistance.

Conclusion: Findings underscore the importance of early education and screening, especially among high-risk clinical populations. Increased resources and supports for professionals, parents, and peers are indicated, along with countering the persistent stigma associated with ADHD and NSSDV.

目的:非自杀性自导暴力(NSSDV)是一个重大且日益严重的青少年公共健康危机。患有多动症的女孩参与 NSSDV 的风险更高,但目前还缺乏对这一人群的定性研究,以更好地了解其表现形式、动机和发展过程:我们对 57 名年轻女性(32 名儿童多动症患者,25 名神经典型比较者;平均年龄 27 岁,是一项大型前瞻性纵向研究的一部分)进行了有关 NSSDV 历史和表现的半结构化定性访谈:结果:归纳和演绎分析揭示了几个关键主题,包括参与 NSSDV 的自我认知原因(情绪调节、寻求关注、自我惩罚、坚持控制)、冲动性、隐秘性,以及在某些情况下放弃的动机:研究结果强调了早期教育和筛查的重要性,尤其是在高危临床人群中。研究结果强调了早期教育和筛查的重要性,尤其是在高危临床人群中。需要为专业人士、家长和同伴提供更多的资源和支持,同时消除与多动症和 NSSDV 相关的顽固污名。
{"title":"A Qualitative Analysis of Perspectives on Self-directed Violence in a Prospective Longitudinal Study of Young Women With and Without Childhood ADHD.","authors":"Shaikh I Ahmad, Stephen P Hinshaw","doi":"10.1177/10870547231221729","DOIUrl":"10.1177/10870547231221729","url":null,"abstract":"<p><strong>Objective: </strong>Non-suicidal self-directed violence (NSSDV) is a significant and growing youth public health crisis. Girls with ADHD are at increased risk of engaging in NSSDV, yet qualitative studies with this population-to better understand manifestations, motivations, and developmental course-are lacking.</p><p><strong>Method: </strong>We conducted semi-structured, qualitative interviews with a sub-sample of 57 young women (32 with childhood ADHD, 25 neurotypical comparisons; mean age of 27 years, part of a larger prospective longitudinal study) regarding histories and manifestations of NSSDV.</p><p><strong>Results: </strong>Inductive and deductive analysis revealed several key themes, including self-perceived reasons for engaging in NSSDV (affect regulation, attention seeking, self-punishment, asserting control), impulsivity, secretiveness, and in some cases motivations for desistance.</p><p><strong>Conclusion: </strong>Findings underscore the importance of early education and screening, especially among high-risk clinical populations. Increased resources and supports for professionals, parents, and peers are indicated, along with countering the persistent stigma associated with ADHD and NSSDV.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"1255-1266"},"PeriodicalIF":3.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11168017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139642214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Sex on Cognitive Control in ADHD: Girls Slow to Inhibit, Boys Inhibit Less, and Both Show Higher Response Variability. 性别对多动症认知控制的影响:女孩抑制迟缓,男孩抑制较少,且都表现出较高的反应变异性。
IF 2.7 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-07-01 Epub Date: 2024-03-16 DOI: 10.1177/10870547241237242
Beatrice Ojuri, Alyssa DeRonda, Micah Plotkin, Stewart H Mostofsky, Keri S Rosch

Objective: To determine whether girls and boys with ADHD show distinct impairments in components of cognitive control across multiple tasks (go/no-go, stop signal, and flanker) and performance metrics (response speed, variability, and errors).

Method: A total of 300 children, ages 8 to 12 years with ADHD (n = 210, 58 girls) or typically developing (TD; n = 99, 37 girls), completed all tasks. Traditional response measures (e.g., mean and standard deviation of reaction time, inhibition errors, and stop signal reaction time) and ex-Gaussian modeling of reaction times (mu, sigma, and tau) were analyzed.

Results: Girls showed intact response inhibition in the context of slower response speed, while boys made more inhibition errors and did not slow their response speed. Both girls and boys with ADHD showed higher response variability and poorer interference control than TD children.

Conclusion: Girls and boys with ADHD show distinct impairments in cognitive control that may be important for understanding the pathophysiology of ADHD.

目的确定患有多动症的女孩和男孩在多项任务(走/不走、停止信号和侧翼)和表现指标(反应速度、变异性和错误)中的认知控制部分是否表现出明显的缺陷:共有 300 名 8 至 12 岁患有多动症(n = 210,58 名女孩)或发育正常(TD;n = 99,37 名女孩)的儿童完成了所有任务。对传统的反应测量(如反应时间的平均值和标准偏差、抑制误差和停止信号反应时间)和反应时间的前高斯模型(mu、sigma和tau)进行了分析:结果:在反应速度较慢的情况下,女孩表现出了完整的反应抑制,而男孩则出现了更多的抑制错误,反应速度也没有减慢。与 TD 儿童相比,患有多动症的女孩和男孩都表现出更高的反应变异性和更差的干扰控制能力:结论:患有多动症的女孩和男孩在认知控制方面表现出明显的缺陷,这对于了解多动症的病理生理学可能非常重要。
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引用次数: 0
Probiotics as a Promising Therapy in Improvement of Symptoms in Children With ADHD: A Systematic Review. 益生菌是改善多动症儿童症状的有效疗法:系统回顾
IF 3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-06-01 Epub Date: 2024-02-18 DOI: 10.1177/10870547241228828
Mahsa Nahidi, Saman Soleimanpour, Maryam Emadzadeh

Background: ADHD is widely recognized as the most prevalent neurodevelopmental disorder in children. Recently, the potential role of gut microbiota as an etiological factor in ADHD has gained attention. This systematic review aims to investigate the potential impact of probiotic supplements on alleviating ADHD symptoms and influencing behavior.

Methods: PubMed, Web of Science, Cochrane Library, and SCOPUS were searched from inception to May 2023. Only randomized controlled trials that have suitable data of the effects of probiotics/synbiotics on children with ADHD were enrolled. The risk of bias of the included studies was assessed by Cochrane Collaboration risk of bias tool.

Results: Five related randomized controlled trial were evaluated in the current review. Types of interventions ranged from single/multi strain probiotics to synbiotic. The duration of intervention in all of the studies were 2 to 3 months. The assessed outcomes were very diverse and different tools were used to report the symptoms in children. Among those which used Conners' Parent Rating Scale, a decrease in the total score occurred in the probiotic group, compared to the placebo group. An improvement in both intervention and control groups was seen in one study which used ADHD-Rating Scale.

Conclusion: In summary, the combined findings from the reviewed studies suggest that probiotic supplements might potentially serve as a complementary intervention for ADHD. However, given the small number of studies, limited sample sizes, and the diversity of probiotic strains, further research is needed to clarify the effects of probiotics in children with ADHD. The observed tolerability of probiotics is noteworthy as none of the studies report adverse effects.

背景:多动症被公认为是儿童中最常见的神经发育障碍。最近,肠道微生物群作为多动症病因的潜在作用受到了关注。本系统综述旨在研究益生菌补充剂对缓解多动症症状和影响行为的潜在影响:方法:检索了从开始到 2023 年 5 月的 PubMed、Web of Science、Cochrane Library 和 SCOPUS。仅纳入了有关于益生菌/合成益生菌对多动症儿童影响的适当数据的随机对照试验。纳入研究的偏倚风险由 Cochrane 协作偏倚风险工具进行评估:本综述评估了五项相关的随机对照试验。干预类型包括单株/多株益生菌和合成益生菌。所有研究的干预时间均为 2 至 3 个月。评估的结果多种多样,报告儿童症状的工具也各不相同。在使用康纳斯家长评分量表的研究中,与安慰剂组相比,益生菌组的总分有所下降。在一项使用多动症评分量表的研究中,干预组和对照组的症状都有所改善:总之,综述研究结果表明,益生菌补充剂有可能成为治疗多动症的辅助干预措施。然而,鉴于研究数量少、样本量有限以及益生菌菌株的多样性,还需要进一步的研究来明确益生菌对多动症儿童的影响。值得注意的是益生菌的耐受性,因为没有一项研究报告了不良反应。
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引用次数: 0
The Beginnings of Attention Deficit in a Dutch 18th Century Medical Treatise. 荷兰 18 世纪医学论文中注意力缺陷的开端。
IF 3 3区 医学 Q2 PSYCHIATRY Pub Date : 2024-06-01 Epub Date: 2024-03-18 DOI: 10.1177/10870547241238926
Michiel W van Kernebeek, Cleo L Crunelle

Objective: An early description, possibly the earliest, of attention deficit disorder in a 1753 Dutch medical book by Cornelius Kloekhof is presented.

Method: The author of this text is briefly introduced and contextualized. The text is translated from Latin and afterwards, its impact on later scientific literature is discussed.

Results and conclusions: Kloekhofs description of attention deficit was one of the first and thoroughly inspired the subsequent literature, such as Adam Weikard, making this text an important moment in the rich history of ADHD.

目的:介绍科尼利厄斯-克勒霍夫(Cornelius Kloekhof)在 1753 年荷兰医学书籍中对注意力缺陷障碍的早期描述,这可能是最早的描述:方法:简要介绍该书的作者和背景。方法:简要介绍该书的作者和背景,将该书翻译成拉丁文,然后讨论该书对后来科学文献的影响:Kloekhof 对注意力缺陷的描述是最早的描述之一,并对亚当-魏卡德等后来的文献产生了深远的影响,使这本书成为多动症丰富历史中的一个重要时刻。
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引用次数: 0
期刊
Journal of Attention Disorders
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