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Trajectory Moderators of Functional Outcomes and ADHD Symptoms in Children With ADHD. ADHD儿童功能结局和ADHD症状的轨迹调节因子
IF 2.2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-11 DOI: 10.1177/10870547251367284
Margaret Fletcher, Susan Silva, Wei Pan, Karin Reuter-Rice

Objective: ADHD can impair children's functioning. Socioeconomic and sociodemographic factors present barriers to treatment access and lead to disparate outcomes in children with ADHD. The purpose of this study was to describe trajectories of functional outcomes and ADHD symptom counts across 3 years and explore the moderating effects of income and race/ethnicity on these trajectories among U.S. children with ADHD.

Method: This longitudinal study of children currently and/or previously meeting diagnostic criteria for ADHD (N = 1,587, age = 9-10 years at baseline) used data from the Adolescent Brain Cognitive Development (ABCD) Study®. Outcomes were child-reported functional outcome measures (family conflict, prosocial behavior, and school experiences) and parent-reported inattentive and hyperactive symptom counts across 3 years. Multi-level, mixed-effects models for longitudinal data were used to characterize each outcome trajectory and examine the moderating effects of baseline household income and race/ethnicity.

Results: The sample was 68% male and 54% White, with 53% meeting diagnostic criteria for past-only ADHD, 12% current-only ADHD, and 35% both past and current ADHD. Significant changes in family conflict, school experiences, inattentive symptom counts, and hyperactive symptom counts were demonstrated across 3 years (trajectories, p < .05). Income significantly moderated prosocial behavior trajectories, while race/ethnicity significantly moderated family conflict and prosocial behavior trajectories (time interaction, p < .05).

Conclusions: The findings suggest that factors related to income and race/ethnicity influence trajectories of change in family conflict and prosocial behavior outcomes in children with a history of ADHD. Future studies should explore these disparities and identify targets for intervention, such as increased access to diagnosis and treatment for individuals at risk of poorer functional outcomes.

目的:ADHD会损害儿童的功能。社会经济和社会人口因素对ADHD儿童的治疗提供了障碍,并导致不同的结果。本研究的目的是描述3年内功能结果和ADHD症状计数的轨迹,并探讨收入和种族/民族对美国ADHD儿童这些轨迹的调节作用。方法:对目前和/或以前符合ADHD诊断标准的儿童(N = 1,587,基线年龄= 9-10岁)进行纵向研究,使用来自青少年大脑认知发展(ABCD)研究®的数据。结果是儿童报告的功能结果测量(家庭冲突、亲社会行为和学校经历)和家长报告的3年内注意力不集中和多动症状计数。使用纵向数据的多级混合效应模型来描述每个结果轨迹,并检查基线家庭收入和种族/民族的调节作用。结果:样本中68%为男性,54%为白人,53%符合过去ADHD诊断标准,12%符合当前ADHD诊断标准,35%同时符合过去和当前ADHD诊断标准。3年间,家庭冲突、学校经历、注意力不集中症状计数和多动症状计数发生了显著变化(轨迹,p)。结论:研究结果表明,与收入和种族/民族相关的因素影响有ADHD病史儿童家庭冲突和亲社会行为结果的变化轨迹。未来的研究应该探索这些差异并确定干预的目标,例如增加对有较差功能预后风险的个体的诊断和治疗。
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引用次数: 0
School-Based Social Skills Interventions for Youth With ADHD: A Systematic Review and Meta-Analysis. 以学校为基础的社会技能干预青少年多动症:系统回顾和荟萃分析。
IF 2.2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-04 DOI: 10.1177/10870547251364578
Gabriella Bussanich, Judith R Harrison, Corey Peltier, Aayushi Patel, Paulomi Mehta, Kashees Patel

ObjectiveChildren and adolescents frequently struggle with social skills performance in academic settings, which can negatively impact quality of life. As such, social skills training is frequently recommended; however, the effectiveness of school-based social skills training has not been synthesized. As such, the purpose of the current study was to evaluate the empirical evidence pertaining to both stand-alone and multimodal school-based social skills programs for students with ADHD, and to assess the effects of potential moderating variables.

Method: A systematic review and meta-analysis was conducted of studies between the years of 1975 and 2023 following the recommendations of the Cochrane Foundation and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).

Results: Seventeen studies, single-case, within group, and between-group designs met the established inclusion criteria, with 10 included in the meta-analysis. The findings revealed small to large effects; however, the overall meta-analytic effect size was negligible (ES = 0.09). The differences in social skills approaches, intensity, parent involvement, and setting did not moderate the effects.

Conclusion: These findings underscore the necessity for ongoing exploration and refinement of social skills interventions tailored for youth with ADHD.

儿童和青少年经常在学术环境中与社交技能表现作斗争,这可能会对生活质量产生负面影响。因此,经常建议进行社交技能培训;然而,以学校为基础的社会技能培训的有效性尚未得到综合。因此,本研究的目的是评估与ADHD学生的独立和多模式学校社会技能课程相关的经验证据,并评估潜在调节变量的影响。方法:根据Cochrane基金会和系统评价和荟萃分析首选报告项目(PRISMA)的建议,对1975年至2023年间的研究进行系统评价和荟萃分析。结果:17项研究,单例、组内和组间设计符合既定的纳入标准,其中10项纳入meta分析。研究结果揭示了小到大的影响;然而,总体meta分析效应大小可以忽略不计(ES = 0.09)。社交技巧方法、强度、父母参与和环境的差异并没有缓和这种影响。结论:这些发现强调了为青少年多动症量身定制的社会技能干预的持续探索和完善的必要性。
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引用次数: 0
Cognitive Disengagement Syndrome is Clinically Distinct from ADHD Presentations within Childhood and Adolescence. 认知脱离综合征在临床上不同于儿童和青少年时期的ADHD表现。
IF 2.2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-01 Epub Date: 2025-06-27 DOI: 10.1177/10870547251344719
G Leonard Burns, Stephen P Becker, Juan José Montaño, Belén Sáez, Mateu Servera

Objective: The objective was to determine the differential validity of a cognitive disengagement syndrome-only (CDS-only) group from ADHD-inattentive presentation-only (IN-only), ADHD-hyperactive-impulsive presentation-only (HI-only), and ADHD-combined presentation (C-only) groups within childhood (ages 5-10) and adolescence (ages 11-16).

Methods: Parents of a nationally representative sample of 5,525 Spanish youth (ages 5-16, 56.1% boys) completed measures of CDS, ADHD-inattention (IN), and ADHD-hyperactivity/impulsivity (HI) and other measures. Scores greater/less than the top 5% on CDS, IN, and HI were used to create: (1) control, (2) CDS-only, (3) ADHD-IN-only, (4) ADHD-HI-only, (5) ADHD-C-only, (6) CDS + ADHD-IN, (7) CDS + ADHD-HI, and (8) CDS + ADHD-C groups within childhood and adolescence.

Results: Within childhood, the CDS-only group had higher scores than the three ADHD presentations on anxiety, depression, somatization, daytime sleep-related impairment, nighttime sleep disturbance, social impairment, and peer withdrawal, whereas CDS-only, ADHD-IN-only, and ADHD-HI-only groups did not differ on oppositional defiant disorder (ODD) and academic impairment (ADHD-C-only higher). Within adolescence, the CDS-only group again had higher scores than the three ADHD presentations on somatization and daytime sleep-related impairment but was now lower than the three ADHD presentations on ODD as well as lower on academic impairment than the ADHD-IN-only and ADHD-C-only groups. Within adolescence, the CDS-only group and the three ADHD presentations did not differ on depression, social impairment, or peer withdrawal.

Conclusion: The CDS-only group had strong differential validity from ADHD-IN-only, ADHD-HI-only, and ADHD-C-only groups within childhood with less striking differences in adolescence. In addition to more studies with adolescents, etiological models with multi-informant longitudinal data are needed to better understand the differences in CDS and ADHD dimensions and their changes across development.

目的:目的是确定儿童(5-10岁)和青少年(11-16岁)仅认知脱离综合征(CDS-only)组与仅adhd -不注意表现(IN-only)、仅adhd -多动-冲动表现(HI-only)和仅adhd -合并表现(C-only)组的差异效度。方法:5525名西班牙青少年(5-16岁,56.1%为男孩)的父母完成了CDS、adhd -注意力不集中(IN)和adhd -多动/冲动(HI)等测量。在cd、IN和HI上得分高于或低于前5%的人被用来创建:(1)对照组,(2)仅限cd,(3)仅限ADHD-IN,(4)仅限ADHD-HI,(5)仅限ADHD-C, (6) cd + ADHD-IN, (7) cd + ADHD-HI, (8) cd + ADHD-C儿童和青少年组。结果:在儿童时期,仅cd组在焦虑、抑郁、躯体化、白天睡眠相关障碍、夜间睡眠障碍、社交障碍和同伴退缩方面的得分高于三种ADHD表现,而仅cd组、仅ADHD- in组和仅ADHD- hi组在对立违抗障碍(ODD)和学业障碍(ADHD- c -only更高)方面没有差异。在青少年时期,仅cd组在躯体化和日间睡眠相关障碍方面的得分再次高于三种ADHD表现,但在ODD方面的得分低于三种ADHD表现,在学业障碍方面的得分低于仅ADHD- in组和仅ADHD- c组。在青春期,只有cd的组和三种ADHD表现在抑郁、社交障碍或同伴退缩方面没有差异。结论:单纯cd组与单纯adhd - in组、单纯adhd - hi组和单纯adhd - c组在儿童期具有较强的差异效度,在青春期差异不显著。除了对青少年进行更多的研究外,还需要多信息纵向数据的病因学模型,以更好地了解CDS和ADHD维度的差异及其在发育过程中的变化。
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引用次数: 0
Unraveling ADHD Through Eye-Tracking Procedures: A Scoping Review. 通过眼动追踪程序揭示ADHD:一个范围审查。
IF 2.2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-01 Epub Date: 2025-06-17 DOI: 10.1177/10870547251344731
Georgia Andreou, Ariadni Argatzopoulou

Objective: This scoping review aimed to examine the application of eye-tracking technology in children with Attention-Deficit/Hyperactivity Disorder (ADHD), focusing on the scientific fields involved, methodologies employed, research goals, and outcomes related to its effectiveness.

Method: Following PRISMA guidelines for Scoping Reviews, a total of 22 studies using eye-tracking with children diagnosed with ADHD were identified and analyzed. Data were extracted regarding study aims, methodological approaches, disciplinary origins, and key findings.

Results: The majority of studies originated from neuroscience and psychiatry, with contributions from artificial intelligence, machine learning, virtual reality, and biomedical engineering. Eye-tracking technology was used for three main purposes: (1) identification and diagnosis of ADHD, (2) investigation of cognitive and behavioral mechanisms-particularly attention and inhibitory control, and (3) as an intervention tool to improve cognitive functions. Findings indicated that eye-tracking, especially when integrated with virtual reality or machine learning, may support efficient ADHD diagnosis. Moreover, studies reported that distinct eye movement patterns are associated with attention deficits, inhibitory control issues, impaired working memory, and challenges in emotional and social processing. Interventions using eye-tracking demonstrated potential in training attention control and motor coordination.

Conclusion: Eye-tracking technology holds promise as both a diagnostic and interventional tool for children with ADHD. Future research should address methodological limitations, explore long-term effectiveness, and further investigate multimodal integration with emerging technologies.

目的:本综述旨在探讨眼动追踪技术在儿童注意力缺陷多动障碍(ADHD)中的应用,重点关注其涉及的科学领域、采用的方法、研究目标以及与其有效性相关的结果。方法:根据PRISMA的范围审查指南,对22项使用眼动追踪诊断为ADHD的儿童的研究进行识别和分析。提取有关研究目的、方法学方法、学科起源和主要发现的数据。结果:大多数研究来自神经科学和精神病学,人工智能、机器学习、虚拟现实和生物医学工程也有贡献。眼动追踪技术被用于三个主要目的:(1)ADHD的识别和诊断;(2)认知和行为机制的研究——特别是注意和抑制控制;(3)作为改善认知功能的干预工具。研究结果表明,眼球追踪,特别是与虚拟现实或机器学习相结合,可能支持有效的ADHD诊断。此外,研究报告称,不同的眼动模式与注意力缺陷、抑制控制问题、工作记忆受损以及情绪和社会处理方面的挑战有关。使用眼动追踪的干预在训练注意力控制和运动协调方面具有潜力。结论:眼动追踪技术有望成为儿童多动症的诊断和干预工具。未来的研究应该解决方法上的局限性,探索长期有效性,并进一步研究与新兴技术的多模式集成。
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引用次数: 0
Influence of National Traumatic Events on Inattention and Hyperactivity/Impulsivity Symptoms in Young Adults With and Without ADHD. 国家创伤性事件对有或无多动症青年注意力不集中、多动/冲动症状的影响
IF 2.2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-01 Epub Date: 2025-06-30 DOI: 10.1177/10870547251351442
Tal Erdinast, Gili Katabi, Abraham Weizman, Iris Manor, Nitzan Shahar

Objective: Previous studies indicate that national traumatic events, particularly terror attacks, have a broad impact on the general population, including individuals not directly exposed. However, research on how such events affect inattention and hyperactivity/impulsivity symptoms in individuals with ADHD remains limited.

Method: This study examined the impact of the October 7 terror attack in Israel on ADHD-related symptoms. Young adults with and without ADHD (43 ADHD and 42 control) completed assessments of current and childhood ADHD symptoms, as well as anxiety, at two time-points: before and after the national traumatic event. Participants also reported their level of exposure to the October 7 attack and the subsequent war.

Results: The control group showed a substantial increase in inattention and hyperactivity/impulsivity symptoms after the attack, whereas the ADHD group exhibited no such increase and instead showed a slight reduction in symptom severity. Changes in symptoms in both groups were not influenced by direct exposure to an immediate threat. The increase in symptom severity tended to decline over time and was positively correlated with heightened anxiety symptoms.

Conclusion: These results suggest that national traumatic events can temporarily increase inattention and hyperactivity/impulsivity symptoms among young adults without an ADHD diagnosis, even if they were not directly exposed to the events. This increase tends to return to baseline over time. Conversely, individuals diagnosed with ADHD did not experience a worsening of symptoms and instead showed a slight reduction in severity, particularly in inattention, following the traumatic event. Future research should further explore the functional capabilities of individuals with ADHD under acute stress to deepen the understanding of this relationship.

目的:以往的研究表明,国家创伤性事件,特别是恐怖袭击,对普通人群有广泛的影响,包括没有直接暴露的个人。然而,关于这些事件如何影响多动症患者注意力不集中和多动/冲动症状的研究仍然有限。方法:本研究考察了10月7日以色列恐怖袭击对adhd相关症状的影响。有和没有多动症的年轻人(43名多动症和42名对照组)在两个时间点完成了当前和童年多动症症状以及焦虑的评估:在国家创伤事件之前和之后。参与者还报告了他们对10月7日袭击和随后的战争的暴露程度。结果:对照组在发作后注意力不集中和多动/冲动症状明显增加,而ADHD组没有这种增加,反而症状严重程度略有降低。两组患者的症状变化不受直接暴露于即时威胁的影响。随着时间的推移,症状严重程度的增加倾向于下降,并与焦虑症状的加剧呈正相关。结论:这些结果表明,全国性创伤性事件可以暂时增加没有ADHD诊断的年轻人的注意力不集中和多动/冲动症状,即使他们没有直接接触这些事件。随着时间的推移,这种增长倾向于回到基线水平。相反,被诊断为多动症的个体在创伤事件后并没有经历症状的恶化,反而表现出轻微的严重程度减轻,尤其是在注意力不集中方面。未来的研究应进一步探索ADHD个体在急性压力下的功能能力,以加深对这种关系的理解。
{"title":"Influence of National Traumatic Events on Inattention and Hyperactivity/Impulsivity Symptoms in Young Adults With and Without ADHD.","authors":"Tal Erdinast, Gili Katabi, Abraham Weizman, Iris Manor, Nitzan Shahar","doi":"10.1177/10870547251351442","DOIUrl":"10.1177/10870547251351442","url":null,"abstract":"<p><strong>Objective: </strong>Previous studies indicate that national traumatic events, particularly terror attacks, have a broad impact on the general population, including individuals not directly exposed. However, research on how such events affect inattention and hyperactivity/impulsivity symptoms in individuals with ADHD remains limited.</p><p><strong>Method: </strong>This study examined the impact of the October 7 terror attack in Israel on ADHD-related symptoms. Young adults with and without ADHD (43 ADHD and 42 control) completed assessments of current and childhood ADHD symptoms, as well as anxiety, at two time-points: before and after the national traumatic event. Participants also reported their level of exposure to the October 7 attack and the subsequent war.</p><p><strong>Results: </strong>The control group showed a substantial increase in inattention and hyperactivity/impulsivity symptoms after the attack, whereas the ADHD group exhibited no such increase and instead showed a slight reduction in symptom severity. Changes in symptoms in both groups were not influenced by direct exposure to an immediate threat. The increase in symptom severity tended to decline over time and was positively correlated with heightened anxiety symptoms.</p><p><strong>Conclusion: </strong>These results suggest that national traumatic events can temporarily increase inattention and hyperactivity/impulsivity symptoms among young adults without an ADHD diagnosis, even if they were not directly exposed to the events. This increase tends to return to baseline over time. Conversely, individuals diagnosed with ADHD did not experience a worsening of symptoms and instead showed a slight reduction in severity, particularly in inattention, following the traumatic event. Future research should further explore the functional capabilities of individuals with ADHD under acute stress to deepen the understanding of this relationship.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"1024-1035"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do Infant Heart Rate Variability and Visual Attention Predict Autism and Concerns for ADHD? 婴儿心率变异性和视觉注意能预测自闭症和ADHD吗?
IF 2.2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-01 Epub Date: 2025-06-17 DOI: 10.1177/10870547251345539
Emma M Jaisle, Erica D Musser, Maylinn Yon, Susana Garcia, Antonia M H Piergies, Meghan Miller

Objective: Investigate whether patterns of heart rate variability (indexed via respiratory sinus arrhythmia) and visual attention at 12 to 18 months of age predict elevated ADHD symptoms, autism, or neither during the preschool period.

Method: Ninety infants 12 to 18 months of age (M = 17.27, SD = 1.93; 36 females; 82.2% non-Hispanic) participated in a split-screen eye-tracking task of dynamic social and non-social moving objects. Respiratory sinus arrhythmia was derived from heart rate data collected at baseline and during the task condition. Between 24 and 65 months of age (M = 38.22, SD = 11.14), participants were evaluated and classified into one of three outcome groups: ADHD Concerns (n = 21), Autism (n = 12), or Comparison (i.e., non-Autism/non-ADHD Concerns; n = 57).

Results: The ADHD Concerns group exhibited significantly less whole-screen looking time (t(76) = -2.98, p = .004, d = 0.82) and spent a significantly lower proportion of time attending to the social portion of the stimulus (t(76) = -2.53, p = .01, d = 0.67) than the Comparison group. Respiratory sinus arrhythmia reactivity moderated the association between proportion of time spent looking at the social portion of the stimulus in infancy and ADHD symptoms during the preschool period (b = 0.004, 95% CI [0.0001, 0.01], t(89) = 2.11, p = .04), such that greater quantity/intensity of ADHD symptoms was associated with a smaller proportion of look time to the social portion of the stimulus for infants engaging in HRV withdrawal, but not HRV augmentation. Hypotheses focused on autism were not supported.

Conclusions: Infants demonstrate distinct patterns of visual attention predictive of elevated ADHD symptoms in the preschool period. Heart rate variability may also demonstrate predictive utility in the context of early ADHD when examined in relation to social attention, but not independently.

目的:研究12 - 18月龄的心率变异性(以呼吸窦性心律失常为指标)和视觉注意模式是否能预测学龄前儿童ADHD症状、自闭症或两者均未升高。方法:90例12 ~ 18月龄婴儿(M = 17.27, SD = 1.93;36岁女性;(82.2%,非西班牙裔)参与了动态社会和非社会运动物体的分屏眼动追踪任务。呼吸性窦性心律失常来源于基线和任务条件下收集的心率数据。在24到65个月大之间(M = 38.22, SD = 11.14),参与者被评估并分为三个结果组之一:ADHD关注(n = 21),自闭症(n = 12),或比较(即非自闭症/非ADHD关注;n = 57)。结果:ADHD关注组的全屏幕注视时间明显减少(t(76) = -2.98, p =。004, d = 0.82),并且花费在社会刺激部分的时间比例显著低于(t(76) = -2.53, p =。0.01, d = 0.67)。呼吸窦性心律失常的反应性调节了婴儿观察刺激的社交部分的时间比例与学龄前ADHD症状之间的关联(b = 0.004, 95% CI [0.0001, 0.01], t(89) = 2.11, p = 0.04),因此,对于HRV戒断而不是HRV增强的婴儿,ADHD症状的数量/强度越大,观察刺激的社交部分的时间比例越小。针对自闭症的假设没有得到支持。结论:婴儿表现出明显的视觉注意模式,预示着学龄前ADHD症状的升高。心率变异性也可能在早期ADHD的背景下显示预测效用,当检查与社会注意力有关时,但不是独立的。
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引用次数: 0
Implications of Co-occurrence Between ADHD and Anxiety in a Community-based Child Sample. 以社区为基础的儿童样本中ADHD和焦虑共存的意义。
IF 2.2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-01 Epub Date: 2025-03-25 DOI: 10.1177/10870547251324806
Sonia Tremblay, Erik G Willcutt

Objective: The current study aimed to elucidate characteristics of co-occurring ADHD and anxiety in a community-based sample of children. Previous work has highlighted the prevalence and associated impairment of each condition alone, but less research has focused on the co-occurrence of these disorders.

Method: The present study first sought to examine the prevalence of this co-occurrence in a sample of 2,257 school-age children. The study also compared academic, social, and adaptive impairment among children with ADHD alone, anxiety alone, both ADHD and anxiety, or neither condition. Lastly, the study explored sex differences in the prevalence of co-occurring ADHD and anxiety and their associated impairment.

Results: Results supported previous findings surrounding prevalence of the co-occurrence, as children with ADHD were over twice as likely to exhibit elevated anxiety than children without ADHD. While ADHD was more common in boys, among all children with ADHD more girls displayed co-occurring anxiety. Both ADHD and anxiety were associated with impairment in nearly all domains of functioning, but children with both conditions broadly displayed the most functional impairment.

Conclusion: Results of the current study underscore the clinical relevance of the co-occurrence between ADHD and anxiety in children and suggest that future research is warranted to further investigate this phenomenon.

目的:本研究旨在阐明以社区为基础的儿童样本中ADHD和焦虑共存的特征。以前的工作强调了每种疾病的患病率和相关损害,但很少有研究关注这些疾病的共同发生。方法:本研究首先试图在2257名学龄儿童的样本中检查这种共同发生的患病率。该研究还比较了单独患有多动症的儿童、单独患有焦虑症的儿童、同时患有多动症和焦虑症的儿童、或者两者都没有的儿童的学业、社交和适应性障碍。最后,该研究探讨了ADHD和焦虑共存的患病率及其相关损害的性别差异。结果:研究结果支持了先前的研究结果,即ADHD儿童表现出焦虑升高的可能性是未患ADHD儿童的两倍多。虽然多动症在男孩中更为常见,但在所有患有多动症的儿童中,更多的女孩表现出同时出现的焦虑。多动症和焦虑几乎都与所有功能领域的损害有关,但患有这两种疾病的儿童普遍表现出最严重的功能损害。结论:本研究的结果强调了ADHD与儿童焦虑共存的临床相关性,并提示未来的研究有必要进一步研究这一现象。
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引用次数: 0
Rates of Depression in Children and Adolescents With ADHD: A Systematic Review and Meta-Analysis. 儿童和青少年多动症患者的抑郁率:一项系统回顾和荟萃分析。
IF 2.2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-01 Epub Date: 2025-06-27 DOI: 10.1177/10870547251341597
Shipei Wang, Tracy M Stewart, Isinsu Ozen, Arnab Mukherjee, Sinead M Rhodes

Objective: Accumulating evidence indicates high rates of major depressive disorder (MDD) in children and adolescents with ADHD. This systematic review and meta-analysis aimed to examine the rate of depression in children and adolescents with ADHD who are without intellectual disability (ID).

Method: A comprehensive search of six databases identified 20,745 studies. After screening based on inclusion and exclusion criteria, 24 studies were retained. A meta-analysis estimated the pooled depression rate in this population, and subgroup analyses examined differences based on sex, pubertal status, ADHD medication use, recruitment settings, depression assessment tools, informants, and risk of bias rating. Depression rates in children and adolescents with ADHD were compared with neurotypical peers in the retained case-control studies.

Results: Depression rates in children and adolescents with ADHD across the included studies ranged from 1.7% to 60%, with the meta-analysis estimating a pooled depression rate of 11.31% (95% CI [0.07, 0.16]). Subgroup analyses indicated significant differences by sex, with females showing higher rates than males. Differences were also noted by assessment methods, with the highest rates observed when both questionnaires and interviews were used. While other factors did not significantly affect rates, notable trends were identified and reported in the current article.

Conclusion: Depression is a common co-occurrent psychiatric condition in children and adolescents with ADHD, with rates observed in this review and meta-analysis being higher than those reported for neurotypical children and adolescents. This review underscores the importance of combining multiple assessment methods to capture a comprehensive picture of depression in this population, as well as ensuring balanced demographic representation. This review also suggests that further research should explore the depression developmental patterns in children and adolescents with ADHD and identify whether patterns are similar to the neurotypical population.

目的:越来越多的证据表明,重度抑郁症(MDD)在儿童和青少年多动症患者中发病率很高。本系统综述和荟萃分析旨在检查无智力残疾(ID)的ADHD儿童和青少年抑郁症发生率。方法:对6个数据库进行综合检索,确定了20,745项研究。根据纳入和排除标准筛选后,保留了24项研究。荟萃分析估计了该人群的综合抑郁率,亚组分析检查了基于性别、青春期状态、ADHD药物使用、招募设置、抑郁评估工具、信息提供者和偏倚风险评级的差异。在保留的病例对照研究中,将患有多动症的儿童和青少年的抑郁率与神经正常的同龄人进行比较。结果:在纳入的研究中,患有ADHD的儿童和青少年的抑郁率从1.7%到60%不等,meta分析估计合并抑郁率为11.31% (95% CI[0.07, 0.16])。亚组分析显示性别差异显著,女性的发病率高于男性。评估方法也注意到差异,当问卷调查和访谈同时使用时,观察到的比率最高。虽然其他因素对比率没有显著影响,但本文确定并报告了显著的趋势。结论:抑郁症是ADHD儿童和青少年中常见的共发精神疾病,在本综述和荟萃分析中观察到的发生率高于神经正常的儿童和青少年。这篇综述强调了结合多种评估方法来全面了解这一人群中抑郁症的重要性,并确保均衡的人口代表性。这一综述还表明,进一步的研究应该探索多动症儿童和青少年的抑郁发展模式,并确定模式是否与神经正常人群相似。
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引用次数: 0
Prevalence of ADHD in Preschool Children: A community-based Study from Turkey. 学龄前儿童ADHD患病率:一项来自土耳其的社区研究
IF 2.2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-01 Epub Date: 2025-06-27 DOI: 10.1177/10870547251345178
Sinem Yavuz Ozturk, Nursu Cakin Memik, Sibel Balci, Ebru Karaca

Objective: This study aims to determine the prevalence of Attention Deficit Hyperactivity Disorder (ADHD), considering both parents' and teachers' reports and clinical diagnosis, and to examine the relationship between ADHD prevalence and measurement tools, sex, age, and clinical presentations.

Method: This two-phase epidemiological study was conducted on 689 preschoolers aged 3 to 6 years in Kocaeli, Turkey. In the first phase, the Conners Rating Scale-Revised Long Form and the ADHD Rating Scale-IV Preschool Version were administered to teachers after parents. In the second phase, diagnostic evaluation was performed using DSM-5 ADHD criteria for children scoring above the 93rd percentile on any scale, according to either parent or teacher reports.

Results: The prevalence of ADHD was estimated to range from 2% to 12.6%, depending on the measurement method. The prevalence of ADHD diagnosis was 3.3%, with a male-to-female ratio of 1.9:1. The hyperactive-impulsive presentation (1.62%) was more common than the combined presentation (1.32%) and the inattentive presentation (0.44%).

Conclusion: Our findings are consistent with the literature, emphasizing the importance of ADHD screening in preschool children for early diagnosis. Measurement tools used in ADHD screening and parent-teacher responses should be evaluated carefully.

目的:本研究旨在结合家长和老师的报告和临床诊断,确定ADHD的患病率,并探讨ADHD患病率与测量工具、性别、年龄和临床表现之间的关系。方法:对土耳其科恰埃利地区689名3 ~ 6岁学龄前儿童进行两期流行病学调查。在第一阶段,对教师和家长分别使用康纳斯评定量表-修订长表和ADHD评定量表-四学前版。在第二阶段,根据家长或老师的报告,使用DSM-5 ADHD标准对得分在任何量表的第93百分位以上的儿童进行诊断评估。结果:根据测量方法的不同,ADHD的患病率估计在2%到12.6%之间。ADHD诊断的患病率为3.3%,男女比例为1.9:1。多动冲动表现(1.62%)比合并表现(1.32%)和注意力不集中表现(0.44%)更为常见。结论:我们的发现与文献一致,强调了学龄前儿童ADHD筛查对早期诊断的重要性。用于ADHD筛查和家长-教师反应的测量工具应该仔细评估。
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引用次数: 0
Correlates of Functional Impairment in Adolescents with ADHD: Delineating the Relationship Between Cognitive Disengagement Syndrome and Dissociation. 青少年多动症的相关功能损害:描述认知脱离综合征和分离之间的关系。
IF 2.2 3区 医学 Q2 PSYCHIATRY Pub Date : 2025-09-01 Epub Date: 2025-07-02 DOI: 10.1177/10870547251349245
Yavuz Meral, Mehmet Enes Gökler, Zeynep Seda Albayrak, Hande Kırışman Keleş, Nihal Serdengeçti, Meryem Seçen Yazıcı, Mahmut Cem Tarakçıoğlu

Objective: There is substantial evidence supporting the distinction between cognitive disengagement syndrome (CDS) and attention-deficit/hyperactivity disorder (ADHD), particularly from the inattentive subtype. However, despite proposed etiological and phenomenological similarities, the relationship between CDS and dissociation remains underexplored. This study investigates the relationship between CDS and dissociation and evaluates their combined impact on functional impairment while accounting for comorbid internalizing and externalizing problems in adolescents with ADHD.

Method: A total of 103 adolescents with ADHD (aged 11-17, M = 14.15, SD = 1.71) and their parents participated in this multicenter, cross-sectional study. ADHD diagnosis was established using the Best Estimate Clinical Diagnosis method. Standardized assessments included the Adolescent Dissociative Experiences Scale (A-DES) and the Revised Child Anxiety and Depression Scale-Child Version (RCADS-CV) for self-report, while parents completed the modified version of Sluggish Cognitive Tempo Scale (SCT-S), Strengths and Difficulties Questionnaire-Parent Form (SDQ-P), and Weiss Functional Impairment Rating Scale-Parent Report (WFIRS-P).

Results: No significant correlations were observed between the parent-reported CDS Modified Total and the adolescent-reported A-DES Total score (r = -.024, p = .811), or any of its subdomains, after controlling for anxiety symptoms. Regression analyses revealed that CDS Modified Total (β = .0121, p = .032), and A-DES Absorption & Imaginative Involvement (β = .0085, p = .042) were independent predictors of parent-reported functional impairment along with SDQ-P Emotional Symptoms (β = .0399, p = .040), SDQ-P Conduct Problems (β = .0752, p < .001), RCADS-CV Separation Anxiety Disorder (β = .0245, p = .017). The dominance analysis indicated that the parent-reported SDQ Conduct Problems subscale had the highest average R2 contribution (M = 0.1625) while the parent-reported CDS Modified Total demonstrated the lowest average R2 contribution across models (M = 0.0498).

Conclusion: The findings suggest that CDS and dissociation represent distinct constructs, at least when rated by different informants, and that both may have significant and independent contributions to functional impairment in adolescents with ADHD. These results highlight the need to consider a broader range of contributing factors beyond symptom severity alone for the effective management of ADHD.

目的:有大量证据支持认知脱离综合征(CDS)和注意缺陷/多动障碍(ADHD)之间的区别,特别是不注意亚型。然而,尽管提出了病因学和现象学上的相似性,但CDS和解离之间的关系仍未得到充分探讨。本研究探讨了CDS和分离之间的关系,并评估了它们对功能障碍的综合影响,同时考虑了ADHD青少年共病的内化和外化问题。方法:103例11 ~ 17岁ADHD青少年及其父母参与多中心横断面研究,M = 14.15, SD = 1.71。采用最佳估计临床诊断方法建立ADHD诊断。标准化评估包括青少年分离体验量表(A-DES)和自我报告修订儿童焦虑抑郁量表-儿童版(RCADS-CV),家长完成修正版迟缓认知节奏量表(SCT-S)、优势与困难问卷-家长表(SDQ-P)和韦斯功能障碍评定量表-家长报告(WFIRS-P)。结果:父母报告的CDS修正总分与青少年报告的A-DES总分无显著相关(r = -)。024, p = .811),或其任何子域,在控制焦虑症状后。回归分析显示CDS修正Total (β =。0121, p = .032), A-DES吸收和想象参与(β = .032)。0085, p = .042)是父母报告的功能障碍和SDQ-P情绪症状的独立预测因子(β =。0399, p = .040), SDQ-P行为问题(β =。0752, p p = .017)。优势度分析表明,父母报告的SDQ行为问题子量表的平均R2贡献最高(M = 0.1625),而父母报告的CDS修正总量在各模型中的平均R2贡献最低(M = 0.0498)。结论:研究结果表明,至少在不同的供者评估时,CDS和分离代表了不同的构念,两者都可能对ADHD青少年的功能障碍有显著的独立贡献。这些结果强调需要考虑更广泛的影响因素,而不仅仅是症状严重程度,以有效地管理ADHD。
{"title":"Correlates of Functional Impairment in Adolescents with ADHD: Delineating the Relationship Between Cognitive Disengagement Syndrome and Dissociation.","authors":"Yavuz Meral, Mehmet Enes Gökler, Zeynep Seda Albayrak, Hande Kırışman Keleş, Nihal Serdengeçti, Meryem Seçen Yazıcı, Mahmut Cem Tarakçıoğlu","doi":"10.1177/10870547251349245","DOIUrl":"10.1177/10870547251349245","url":null,"abstract":"<p><strong>Objective: </strong>There is substantial evidence supporting the distinction between cognitive disengagement syndrome (CDS) and attention-deficit/hyperactivity disorder (ADHD), particularly from the inattentive subtype. However, despite proposed etiological and phenomenological similarities, the relationship between CDS and dissociation remains underexplored. This study investigates the relationship between CDS and dissociation and evaluates their combined impact on functional impairment while accounting for comorbid internalizing and externalizing problems in adolescents with ADHD.</p><p><strong>Method: </strong>A total of 103 adolescents with ADHD (aged 11-17, <i>M</i> = 14.15, <i>SD</i> = 1.71) and their parents participated in this multicenter, cross-sectional study. ADHD diagnosis was established using the Best Estimate Clinical Diagnosis method. Standardized assessments included the Adolescent Dissociative Experiences Scale (A-DES) and the Revised Child Anxiety and Depression Scale-Child Version (RCADS-CV) for self-report, while parents completed the modified version of Sluggish Cognitive Tempo Scale (SCT-S), Strengths and Difficulties Questionnaire-Parent Form (SDQ-P), and Weiss Functional Impairment Rating Scale-Parent Report (WFIRS-P).</p><p><strong>Results: </strong>No significant correlations were observed between the parent-reported CDS Modified Total and the adolescent-reported A-DES Total score (<i>r</i> = -.024, <i>p</i> = .811), or any of its subdomains, after controlling for anxiety symptoms. Regression analyses revealed that CDS Modified Total (β = .0121, <i>p</i> = .032), and A-DES Absorption & Imaginative Involvement (β = .0085, <i>p</i> = .042) were independent predictors of parent-reported functional impairment along with SDQ-P Emotional Symptoms (β = .0399, <i>p</i> = .040), SDQ-P Conduct Problems (β = .0752, <i>p</i> < .001), RCADS-CV Separation Anxiety Disorder (β = .0245, <i>p</i> = .017). The dominance analysis indicated that the parent-reported SDQ Conduct Problems subscale had the highest average <i>R</i><sup>2</sup> contribution (<i>M</i> = 0.1625) while the parent-reported CDS Modified Total demonstrated the lowest average <i>R</i><sup>2</sup> contribution across models (<i>M</i> = 0.0498).</p><p><strong>Conclusion: </strong>The findings suggest that CDS and dissociation represent distinct constructs, at least when rated by different informants, and that both may have significant and independent contributions to functional impairment in adolescents with ADHD. These results highlight the need to consider a broader range of contributing factors beyond symptom severity alone for the effective management of ADHD.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"1007-1023"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Attention Disorders
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