Pub Date : 2017-02-13DOI: 10.21065/1920-4159.1000236
Abdullah Bin Junaid, R. Nasreen
The purpose of this study was to understand the key determinants influencing the consumption behaviour of males in the Indian cosmeceutical market. The purpose of this research is to determine different factors that influence male consumption behaviour for different types of male cosmeceutical products in the India market. The focus has been given to males in the age group of 15-50 years in selected states around Delhi. The focus will be on the perception and predisposition that men have towards the cosmeceutical product types. There are different questions related to male cosmeceutical product consumption and which are yet to be answered. To find out the answers of such questions this study is carried out focusing on the male consumption behaviour and more precisely on the factors that are associated with their behaviour. The data was collected through questionnaire from a sample of 300 males. The results were analysed through SPSS software version 16 by applying different statistical tests. Based on the results a conceptual model was developed showing different factors and how these factors influence the male consumption behaviour
{"title":"Cosmeceutical Consumption Behaviour amongst Males in Indian Market Analysisof Determinants and Influencing Factors","authors":"Abdullah Bin Junaid, R. Nasreen","doi":"10.21065/1920-4159.1000236","DOIUrl":"https://doi.org/10.21065/1920-4159.1000236","url":null,"abstract":"The purpose of this study was to understand the key determinants influencing the consumption behaviour of males in the Indian cosmeceutical market. The purpose of this research is to determine different factors that influence male consumption behaviour for different types of male cosmeceutical products in the India market. The focus has been given to males in the age group of 15-50 years in selected states around Delhi. The focus will be on the perception and predisposition that men have towards the cosmeceutical product types. There are different questions related to male cosmeceutical product consumption and which are yet to be answered. To find out the answers of such questions this study is carried out focusing on the male consumption behaviour and more precisely on the factors that are associated with their behaviour. The data was collected through questionnaire from a sample of 300 males. The results were analysed through SPSS software version 16 by applying different statistical tests. Based on the results a conceptual model was developed showing different factors and how these factors influence the male consumption behaviour","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"15 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91112236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-30DOI: 10.21065/1920-4159.1000234
A. Alanazi, Jamir Anwar, Niyaz Alam
The present study aims to evaluate the antidiabetic effect of Morus alba L. stem bark extract in experimental model of diabetes. The animals were divided into six groups as: control group (I); pathogenic control group (II) injected intravenously (i.v.) with single dose of STZ (60 mg/kg); morus alba stem bark extract (group-III; 200 mg/kg), and group-IV (400 mg/kg); group-V animals treated with glibenclamide (5 mg/kg, p.o.) following STZ treatment; group-VI, animals treated with bark extract per se (400 mg/kg). The results of this study showed a significant increase in lipid peroxidation, blood glucose level, glycosylated heamoglobin level, and reduction in glutathione and insulin level after STZ administration. These parameters were significantly (p<0.05) reversed by extracts dose dependently. The biochemical findings were also supported by histopathological studies of pancreas where STZ produced histological changes in pancreas and treatment with Morus alba stem bark extract restored these changes. Thus, we conclude that Morus alba stem bark extracts produced significant antidiabetic and antioxidant effect which might be due to the presence of bioactive components such as phenolic and flavonoid content in the extract. The study warrant the need for further evaluated in certain other models of diabetes
{"title":"Hypoglycemic and Antioxidant Effect of Morus alba L. Stem Bark Extracts in Streptozotocin-Induced Diabetes in Rats","authors":"A. Alanazi, Jamir Anwar, Niyaz Alam","doi":"10.21065/1920-4159.1000234","DOIUrl":"https://doi.org/10.21065/1920-4159.1000234","url":null,"abstract":"The present study aims to evaluate the antidiabetic effect of Morus alba L. stem bark extract in experimental model of diabetes. The animals were divided into six groups as: control group (I); pathogenic control group (II) injected intravenously (i.v.) with single dose of STZ (60 mg/kg); morus alba stem bark extract (group-III; 200 mg/kg), and group-IV (400 mg/kg); group-V animals treated with glibenclamide (5 mg/kg, p.o.) following STZ treatment; group-VI, animals treated with bark extract per se (400 mg/kg). The results of this study showed a significant increase in lipid peroxidation, blood glucose level, glycosylated heamoglobin level, and reduction in glutathione and insulin level after STZ administration. These parameters were significantly (p<0.05) reversed by extracts dose dependently. The biochemical findings were also supported by histopathological studies of pancreas where STZ produced histological changes in pancreas and treatment with Morus alba stem bark extract restored these changes. Thus, we conclude that Morus alba stem bark extracts produced significant antidiabetic and antioxidant effect which might be due to the presence of bioactive components such as phenolic and flavonoid content in the extract. The study warrant the need for further evaluated in certain other models of diabetes","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"6 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2017-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74007387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-05DOI: 10.21065/1920-4159.1000233
Sobhy M. Al-Adl, L. Abdel-Aziz, M. Mohamed
A simple and sensitive spectrophotometric method is described for determination of atorvastatin calcium and rosuvastatin calcium in bulk and tablet forms. The method depends on the formation of colored chromogen between atorvastatin calcium and rosuvastatin calcium and p-dimethylaminobenzaldehyde (PDMAB) in acidic conditions and the reaction mixture exhibits maximum absorbance at λmax 540 and 570 nm for atorvastatin calcium and rosuvastatin calcium, respectively. Under the indicated conditions, this method was linear over the concentration range of 20-160 μg/ml and 2-16 μg/ml for atorvastatin calcium and rosuvastatin calcium, respectively. The method was statistically applied for the determination of drugs in both bulk and tablet forms. Results were compared with reference methods and no significant difference was obtained.
{"title":"Spectrophotometric Determination of Atorvastatin Calcium and RosuvastatinCalcium in Bulk and Dosage Form Using P-Dimethylaminobenzaldehyde","authors":"Sobhy M. Al-Adl, L. Abdel-Aziz, M. Mohamed","doi":"10.21065/1920-4159.1000233","DOIUrl":"https://doi.org/10.21065/1920-4159.1000233","url":null,"abstract":"A simple and sensitive spectrophotometric method is described for determination of atorvastatin calcium and rosuvastatin calcium in bulk and tablet forms. The method depends on the formation of colored chromogen between atorvastatin calcium and rosuvastatin calcium and p-dimethylaminobenzaldehyde (PDMAB) in acidic conditions and the reaction mixture exhibits maximum absorbance at λmax 540 and 570 nm for atorvastatin calcium and rosuvastatin calcium, respectively. Under the indicated conditions, this method was linear over the concentration range of 20-160 μg/ml and 2-16 μg/ml for atorvastatin calcium and rosuvastatin calcium, respectively. The method was statistically applied for the determination of drugs in both bulk and tablet forms. Results were compared with reference methods and no significant difference was obtained.","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"19 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85338985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.21065/1920-4159.1000232
Kamlesh Kn, Sivakumar T, Afroze A
Background: Most of the available antimicrobial drugs have developed resistance; some of them suffer from severe toxicity, side effects. So, there is a need to discover novel compound(s) which should not only be potent, but also less toxic and cost effective. Objectives: The aim of the study is to develop new synthetic antimicrobial agents (Anti-bacterial and anti-fungal) such as 3-substituted flavone/flavanone derivatives, which should be significantly potent with low toxicity. Method: An attempt was made to synthesize a newer series of 3-methyl flavanone derivatives together with the synthesis of a series of 3-hydroxyl flavone analogues. The structures of the test compounds were elucidated and established by UV, IR, H-NMR1, C-NMR13 and mass spectrometry. The synthesized compounds were subjected for in vitro antimicrobial screening using cup plate methods, followed by the determination of zone of inhibitions. Results: Two series (each 10) of 3-methyl flavanone and 3-hydroxy flavone derivatives were synthesized. The structures of the test compounds were characterized and established by various spectroscopic methods. The synthesized compounds were screened for in vitro antibacterial and antifungal activity against different strains (3- Gram positive, 3-Gram negative and 2-fungal strains). Conclusion: Some of the 3-hydroxyl flavones derivatives (1b, 3b, 4b, and 5b) and 3-methyl flavanone derivatives (3a, 1a, 2a and 4a) were found to elicit potent antimicrobial activity. The study revealed that 3-hydroxy flavone derivatives were found to be most active against Gram negative, while 3-methyl flavanone derivatives were active against Gram positive bacteria.
{"title":"Antimicrobial Activity of Flavone Analogues","authors":"Kamlesh Kn, Sivakumar T, Afroze A","doi":"10.21065/1920-4159.1000232","DOIUrl":"https://doi.org/10.21065/1920-4159.1000232","url":null,"abstract":"Background: Most of the available antimicrobial drugs have developed resistance; some of them suffer from severe toxicity, side effects. So, there is a need to discover novel compound(s) which should not only be potent, but also less toxic and cost effective. Objectives: The aim of the study is to develop new synthetic antimicrobial agents (Anti-bacterial and anti-fungal) such as 3-substituted flavone/flavanone derivatives, which should be significantly potent with low toxicity. Method: An attempt was made to synthesize a newer series of 3-methyl flavanone derivatives together with the synthesis of a series of 3-hydroxyl flavone analogues. The structures of the test compounds were elucidated and established by UV, IR, H-NMR1, C-NMR13 and mass spectrometry. The synthesized compounds were subjected for in vitro antimicrobial screening using cup plate methods, followed by the determination of zone of inhibitions. Results: Two series (each 10) of 3-methyl flavanone and 3-hydroxy flavone derivatives were synthesized. The structures of the test compounds were characterized and established by various spectroscopic methods. The synthesized compounds were screened for in vitro antibacterial and antifungal activity against different strains (3- Gram positive, 3-Gram negative and 2-fungal strains). Conclusion: Some of the 3-hydroxyl flavones derivatives (1b, 3b, 4b, and 5b) and 3-methyl flavanone derivatives (3a, 1a, 2a and 4a) were found to elicit potent antimicrobial activity. The study revealed that 3-hydroxy flavone derivatives were found to be most active against Gram negative, while 3-methyl flavanone derivatives were active against Gram positive bacteria.","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"30 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84438839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vancomycin Associated Eosinophilia & Red Man Syndromein a Tertiary Care Hospital","authors":"A. Siddiqui, Zuhaib Jaffer Malik, S. Andleeb","doi":"10.21065/19204159.8.1.7","DOIUrl":"https://doi.org/10.21065/19204159.8.1.7","url":null,"abstract":"","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"277 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77124512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-01DOI: 10.21065/19204159.8.2.23
E. Ahmed, S. Y. Desoukey, M. Fouad, M. Kamel
From the aerial parts of Russelia equisetiformis, eight compounds were isolated (1—8) and identified by different spectral techniques as well as comparison with reported data or authentic samples. The isolated compounds included an alkane (n-pentatriacontane) (1), a mixture of β-sitosterol and stigmasterol (2), a triterpene (lupeol) (3), a mixture of β-sitosterol- and stigmasterol-1-O-β-D-glucopyranosides (4), a phenylpropanoidglucoside (4-Allyl-2,6-dimethoxyphenol-1-O-β-D-glucopyranoside(5), a flavonoid (vitexin) (6) and the two closely related phenylethanoids (acteoside) (7) and isoacteoside (8).
从俄罗斯equisetiformis的空中部分分离出8种化合物(1-8)，并通过不同的光谱技术以及与报告数据或真实样品的比较进行了鉴定。分离得到的化合物包括烷烃(n-五正康烷)(1)，β-谷甾醇和豆甾醇的混合物(2)，三萜(luppeol) (3)， β-谷甾醇-和豆甾醇-1- o -β- d -葡萄糖苷的混合物(4)，苯丙基葡萄糖苷(4-烯丙基-2,6-二甲氧基苯酚-1- o -β- d -葡萄糖苷)(5)，黄酮类(牡荆素)(6)和两种密切相关的苯乙醇(牛油苷)(7)和异牛油苷(8)。
{"title":"CHEMICAL AND BIOLOGICAL STUDIES OF RUSSELIA EQUISETIFORMIS (SCH.&CHAM.) AERIAL PARTS","authors":"E. Ahmed, S. Y. Desoukey, M. Fouad, M. Kamel","doi":"10.21065/19204159.8.2.23","DOIUrl":"https://doi.org/10.21065/19204159.8.2.23","url":null,"abstract":"From the aerial parts of Russelia equisetiformis, eight compounds were isolated (1—8) and identified by different spectral techniques as well as comparison with reported data or authentic samples. The isolated compounds included an alkane (n-pentatriacontane) (1), a mixture of β-sitosterol and stigmasterol (2), a triterpene (lupeol) (3), a mixture of β-sitosterol- and stigmasterol-1-O-β-D-glucopyranosides (4), a phenylpropanoidglucoside (4-Allyl-2,6-dimethoxyphenol-1-O-β-D-glucopyranoside(5), a flavonoid (vitexin) (6) and the two closely related phenylethanoids (acteoside) (7) and isoacteoside (8).","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79906890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-01DOI: 10.21065/19204159.8.3.61
Reshma Kumari, R. Dubey
The antibacterial activity of acetone, methanol, and water-soluble extracts of both leaf and stem of Barleria lupulina were evaluated against some human pathogens viz., Salmonella typhi, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus. The highest antibacterial activities were exhibited at 100% concentrationof all the extracts against the bacterial pathogens. Acetone-soluble leaf (AL) and acetone-soluble stem (AS) extracts caused the maximum zone of inhibition against P. aeruginosa, and methanol-soluble leaf (ML) and methanol-soluble stem (MS) extracts against of Salmonella typhi. However, Klebsiella pneumoniae was inhibited by all the extracts.
{"title":"HPTLC AND GC-MS PROFILE OF BARLERIA LUPULINA LINDL. EXTRACTS AND THEIR EFFECT ON ENTERIC BACTERIAL PATHOGENS","authors":"Reshma Kumari, R. Dubey","doi":"10.21065/19204159.8.3.61","DOIUrl":"https://doi.org/10.21065/19204159.8.3.61","url":null,"abstract":"The antibacterial activity of acetone, methanol, and water-soluble extracts of both leaf and stem of Barleria lupulina were evaluated against some human pathogens viz., Salmonella typhi, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus. The highest antibacterial activities were exhibited at 100% concentrationof all the extracts against the bacterial pathogens. Acetone-soluble leaf (AL) and acetone-soluble stem (AS) extracts caused the maximum zone of inhibition against P. aeruginosa, and methanol-soluble leaf (ML) and methanol-soluble stem (MS) extracts against of Salmonella typhi. However, Klebsiella pneumoniae was inhibited by all the extracts.","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80231799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-01DOI: 10.21065/19204159.8.2.34
S. Rehman, S. Kamal, S. Kiran, I. Bibi, I. Hussain
Caffeine neither causing didn't decrease the risk of cancer, yet it used just to note the activity of cytochrome P-4501A2 (CYP1A2) by converting into its metabolite i.e., paraxanthine. The purpose of the present study was to determine the caffeine and its metabolite phenotypes and their relation to cancer risk in healthy female volunteers of local population in Pakistan. The average value of metabolic ratio [(1,7-dimethylxanthine (17X) and Caffeine 1,3,7-trimethylxanthine (137X)] was found to be 1.182995 ± 0.21137. BMI (used to categorize into different groups, i.e., overweight, underweight etc.) of all volunteers were found to be 19.93Kg/m2. Retention time was 15 and 37 min for 1,7-dimethylxanthine (17DMX) and 1,3,7 trimethylxanthine (137TMX), respectively.
{"title":"MEASUREMENT OF CYP1A2 PHENOTYPE USING FEMALE VOLUNTEER PLASMA: A FOCUS ON CAFFEINE AND PARAXANTHINE AS A PROBE","authors":"S. Rehman, S. Kamal, S. Kiran, I. Bibi, I. Hussain","doi":"10.21065/19204159.8.2.34","DOIUrl":"https://doi.org/10.21065/19204159.8.2.34","url":null,"abstract":"Caffeine neither causing didn't decrease the risk of cancer, yet it used just to note the activity of cytochrome P-4501A2 (CYP1A2) by converting into its metabolite i.e., paraxanthine. The purpose of the present study was to determine the caffeine and its metabolite phenotypes and their relation to cancer risk in healthy female volunteers of local population in Pakistan. The average value of metabolic ratio [(1,7-dimethylxanthine (17X) and Caffeine 1,3,7-trimethylxanthine (137X)] was found to be 1.182995 ± 0.21137. BMI (used to categorize into different groups, i.e., overweight, underweight etc.) of all volunteers were found to be 19.93Kg/m2. Retention time was 15 and 37 min for 1,7-dimethylxanthine (17DMX) and 1,3,7 trimethylxanthine (137TMX), respectively.","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"456 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82952092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The present investigation deals with development and evaluation of mucoadhesive gastroretentive tablet of Norfloxacin using natural polymer from Tamrind seed polysaccharide
本文研究了以罗米子多糖为原料制备诺氟沙星黏附胃保片的工艺
{"title":"FORMULATION DEVELOPMENT AND EVALUATION OF MUCOADHESIVE TABLETS OF NORFLOXACIN CONTAINING NATURAL POLYMER","authors":"Ritesh Rana, R. Bisht, M. Sarangi","doi":"10.21065/19204159.8.1.8","DOIUrl":"https://doi.org/10.21065/19204159.8.1.8","url":null,"abstract":"The present investigation deals with development and evaluation of mucoadhesive gastroretentive tablet of Norfloxacin using natural polymer from Tamrind seed polysaccharide","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87344549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-01DOI: 10.21065/19204159.8.3.43
R. Anil, D. Pravin, R. P. Amol
{"title":"Enhancement of Aqueous Solubility of Ezogabine: Preparation and Characterization of Ezogabine Nanosuspension Anticipated for Nose to Brain Targeting by 32 Factorial Design","authors":"R. Anil, D. Pravin, R. P. Amol","doi":"10.21065/19204159.8.3.43","DOIUrl":"https://doi.org/10.21065/19204159.8.3.43","url":null,"abstract":"","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80365158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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