Beeswax is the substance that is obtained from the structure of a honey comb. The bees secrete wax to build the honey combs to store honey. It has rich hydrophobic property, the beeswax is in fact present within cosmetics and body products. Also, beeswax is used in food industry. Beeswax is a complex mixture of hydrocarbons, free fatty acid, esters of fatty acid. Beeswax plays an important role in Ayurvedic medicine, the traditional medicine name with Madhushistha (Beewax). The Madhushistha is used for the care of wound from abrasion or even from burns with topical application. Some references in Ayurvedic granth highlight the use of Madhushistha in combination with other herbal and mineral mixture, like Sikta Taila, Mruddaharshringa, Jatyadi Taila, etc. Beeswax is mainly of two types, natural beeswax and processed beeswax. Natural beeswax is clarified further heating in water with petroleum waxes. Because of high demand and shortage in market, adulteration of beeswax with cheaper materials are common like animal fat, plant oil and petroleum spirits (Paraffin wax). Hence authenticity of beeswax is major concern and that can be determined by using physico-chemical parameters such as- organoleptic test, solubility, Melting point, Spacific gravity, Refractive index, Acid value, Ester value, Saponification value, volatile matter. With this justification the present study is expected to determine the quality status of four different beeswax samples procured from Mumbai market, western ghats (Natural habitat). The physico-chemical analysis revealed that volatile matter is detected in market sample (2) whereas market sample (1) shows higher melting point as compare to beeswax collected from the Natural habitat. Market sample (1,2) of beeswax shows slight adulteration hence natural habitat samples (1,2) of beeswax should be used in medicine preparation.
{"title":"Physico-chemical Analysis of beeswax procured from Mumbai market, Western Ghats (Natural Habitat)","authors":"Shruti Naik, Sheela Pargunde","doi":"10.21760/jaims.5.5.26","DOIUrl":"https://doi.org/10.21760/jaims.5.5.26","url":null,"abstract":"Beeswax is the substance that is obtained from the structure of a honey comb. The bees secrete wax to build the honey combs to store honey. It has rich hydrophobic property, the beeswax is in fact present within cosmetics and body products. Also, beeswax is used in food industry. Beeswax is a complex mixture of hydrocarbons, free fatty acid, esters of fatty acid. Beeswax plays an important role in Ayurvedic medicine, the traditional medicine name with Madhushistha (Beewax). The Madhushistha is used for the care of wound from abrasion or even from burns with topical application. Some references in Ayurvedic granth highlight the use of Madhushistha in combination with other herbal and mineral mixture, like Sikta Taila, Mruddaharshringa, Jatyadi Taila, etc. Beeswax is mainly of two types, natural beeswax and processed beeswax. Natural beeswax is clarified further heating in water with petroleum waxes. Because of high demand and shortage in market, adulteration of beeswax with cheaper materials are common like animal fat, plant oil and petroleum spirits (Paraffin wax). Hence authenticity of beeswax is major concern and that can be determined by using physico-chemical parameters such as- organoleptic test, solubility, Melting point, Spacific gravity, Refractive index, Acid value, Ester value, Saponification value, volatile matter. With this justification the present study is expected to determine the quality status of four different beeswax samples procured from Mumbai market, western ghats (Natural habitat). The physico-chemical analysis revealed that volatile matter is detected in market sample (2) whereas market sample (1) shows higher melting point as compare to beeswax collected from the Natural habitat. Market sample (1,2) of beeswax shows slight adulteration hence natural habitat samples (1,2) of beeswax should be used in medicine preparation.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123547142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Metabolism is the natural process of the body, which is necessary to maintenance of the homeostasis of an individual person. Everybody constitutions are always in the process of metabolism, which is a combination of Anabolism (Construction) and Catabolism (Deterioration). As Agni is prime factor for all the Chayapachayakriya. Medoroga, is one of the Metabolic disease, in which contributing factors are Agni, Ama along with Kaphapradhana Tridosha, Medodhathu. Due to various types of etiological factors, the Agni in the body gets vitiated and Jatharagnimandya occurs. By this Jatharagnimandya, Dhathuparinama will not occur properly. This will lead to Medoroga and further many other Upadravas. To correct these conditions, Ayurveda has many modes of therapies like Samshodhana, Samshamana. By these we can correct the metabolism from the root cause. Here 40 Subjects diagnosed with Medoroga w.s.r. to Hyperlipidemia fulfilling the Inclusion criteria were selected for study and randomly categorized into two groups as Group A and Group B each consisting of 20 subjects. For both groups Amapachana with Chitrakadi Vati, Sadhyosnehapana with Murchita Sarshapa Taila, Sarvanga Abhyanga with Murchita Tila Taila followed by Swedana. And Virechana was administered with Virechana Gulika. Than each group received two different Shamanoushadhi. So, the objective of the study is to establish the efficacy of Virechana along with Dashanga Guggulu and Virechana along with Shadushana Guggulu in the management of Medoroga.
{"title":"Effect of Virechana Karma along with Guggulu Kalpanas in the management of Medoroga - A Double Arm Study","authors":"Pooja Abhrange, S. G. Chavan, A. Prashanth","doi":"10.21760/jaims.5.5.11","DOIUrl":"https://doi.org/10.21760/jaims.5.5.11","url":null,"abstract":"Metabolism is the natural process of the body, which is necessary to maintenance of the homeostasis of an individual person. Everybody constitutions are always in the process of metabolism, which is a combination of Anabolism (Construction) and Catabolism (Deterioration). As Agni is prime factor for all the Chayapachayakriya. Medoroga, is one of the Metabolic disease, in which contributing factors are Agni, Ama along with Kaphapradhana Tridosha, Medodhathu. Due to various types of etiological factors, the Agni in the body gets vitiated and Jatharagnimandya occurs. By this Jatharagnimandya, Dhathuparinama will not occur properly. This will lead to Medoroga and further many other Upadravas. To correct these conditions, Ayurveda has many modes of therapies like Samshodhana, Samshamana. By these we can correct the metabolism from the root cause. Here 40 Subjects diagnosed with Medoroga w.s.r. to Hyperlipidemia fulfilling the Inclusion criteria were selected for study and randomly categorized into two groups as Group A and Group B each consisting of 20 subjects. For both groups Amapachana with Chitrakadi Vati, Sadhyosnehapana with Murchita Sarshapa Taila, Sarvanga Abhyanga with Murchita Tila Taila followed by Swedana. And Virechana was administered with Virechana Gulika. Than each group received two different Shamanoushadhi. So, the objective of the study is to establish the efficacy of Virechana along with Dashanga Guggulu and Virechana along with Shadushana Guggulu in the management of Medoroga.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126400247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Erandamuladi Kwatha is mentioned in Ayurveda classics as a therapeutic formulation of Basti mainly to treat Trika-prishta Shoola (low back ache). The most common disorder which affects the movement of leg particularly in the productive period of life is low backache. Erandamuladi Kwatha used in Basti contains 15 drugs in which most of the drugs are having Ushna Veerya and are Vatakaphahara in nature. Materials and Methods: Yavakuta Choorna of Erandamuladi Kwatha was evaluated for their pharmacognostic and pharmaceutical analysis. Results and Discussion: Pharmacognostic study showed the presence of contents such as starch grains of Kantakari, rosette crystal of Rasna, pollen grain of Atibala etc. Physico-chemical analysis showed that the loss on drying 7.74%, Ash value 6.78%, Water soluble extract 20.12%, Alcohol soluble extract 4.3%, pH 7.2. Conclusion: From the study, data developed can be espoused for laying down the standards of Erandamuladi Kwatha.
{"title":"Pharmacognostical, phytochemical and HPTLC evaluation of Erandamuladi Kwatha Churna - A polyherbal formulation for pharmaceutical standardization","authors":"S. N, A. Thakar, Harisha C.R., V. Shukla","doi":"10.21760/jaims.5.5.27","DOIUrl":"https://doi.org/10.21760/jaims.5.5.27","url":null,"abstract":"Introduction: Erandamuladi Kwatha is mentioned in Ayurveda classics as a therapeutic formulation of Basti mainly to treat Trika-prishta Shoola (low back ache). The most common disorder which affects the movement of leg particularly in the productive period of life is low backache. Erandamuladi Kwatha used in Basti contains 15 drugs in which most of the drugs are having Ushna Veerya and are Vatakaphahara in nature. Materials and Methods: Yavakuta Choorna of Erandamuladi Kwatha was evaluated for their pharmacognostic and pharmaceutical analysis. Results and Discussion: Pharmacognostic study showed the presence of contents such as starch grains of Kantakari, rosette crystal of Rasna, pollen grain of Atibala etc. Physico-chemical analysis showed that the loss on drying 7.74%, Ash value 6.78%, Water soluble extract 20.12%, Alcohol soluble extract 4.3%, pH 7.2. Conclusion: From the study, data developed can be espoused for laying down the standards of Erandamuladi Kwatha.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122141135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sandhigata Vata is a disease seen commonly both in developing and developed countries. The disease causes mild, moderate or severe degree of morbidity and rarely mortality. The occurrence of problems is increasingly prevalent now a day due to change in lifestyle, food habits and social and cultural changes as well as travelling. Sandhishula, Sandhishotha, Sandhigraha and Atopa are the important clinical features of Sandhigata Vata. According to WHO, Osteoarthritis is the 2nd commonest problem in the world population i.e. 30%. The major risk factors associated with Kneejoint Osteoarthritis are Age, female sex, obesity, occupational Knee bending. Osteoarthritis is the most common articular disorder that begins asymptomatically and is extremely common by age 70. Almost all people by the age 40 have some pathologic change in weight bearing joints. 25% females and 16% males have symptomatic OA. To study the efficacy of Shamananga Sneha in Sandhigata Vata w.s.r. to Osteoarthritis knee. To compare (study) the efficacy of Shamananga Sneha with Shadanga Guggulu in Janu Sandhigata Vata. To compare the results of the two clinical groups. The study was comparative trial and 30 patients with Janu Sandhigata Vata. All the patients were randomly assigned into two groups namely A and B. Group A receive Shamananga Sneha (Guggulu Tiktaka Ghrita) for 30 days, and Group B receive Shamananga Sneha (Guggulu Tiktaka Ghrita) along with Shadanga Guggulu for 30 days. The patients were clinically evaluated and observations were recorded as in the case performa. Shamananga Sneha (Guggulu Tiktaka Ghrita) along with Shadanga Guggulu i.e. group B was more beneficial in relieving the symptoms than Shamananga Sneha i.e. group A (Guggulu Tiktaka Ghrita).
{"title":"Clinical study on Sandhigata Vata w.r.s. to Osteoarthritis and its management by comparing the efficacy of Samananga Sneha and Samananga Sneha with Shadanga Guggulu","authors":"Kavitha Cm, Veena Gd","doi":"10.21760/jaims.5.5.1","DOIUrl":"https://doi.org/10.21760/jaims.5.5.1","url":null,"abstract":"Sandhigata Vata is a disease seen commonly both in developing and developed countries. The disease causes mild, moderate or severe degree of morbidity and rarely mortality. The occurrence of problems is increasingly prevalent now a day due to change in lifestyle, food habits and social and cultural changes as well as travelling. Sandhishula, Sandhishotha, Sandhigraha and Atopa are the important clinical features of Sandhigata Vata. According to WHO, Osteoarthritis is the 2nd commonest problem in the world population i.e. 30%. The major risk factors associated with Kneejoint Osteoarthritis are Age, female sex, obesity, occupational Knee bending. Osteoarthritis is the most common articular disorder that begins asymptomatically and is extremely common by age 70. Almost all people by the age 40 have some pathologic change in weight bearing joints. 25% females and 16% males have symptomatic OA. To study the efficacy of Shamananga Sneha in Sandhigata Vata w.s.r. to Osteoarthritis knee. To compare (study) the efficacy of Shamananga Sneha with Shadanga Guggulu in Janu Sandhigata Vata. To compare the results of the two clinical groups. The study was comparative trial and 30 patients with Janu Sandhigata Vata. All the patients were randomly assigned into two groups namely A and B. Group A receive Shamananga Sneha (Guggulu Tiktaka Ghrita) for 30 days, and Group B receive Shamananga Sneha (Guggulu Tiktaka Ghrita) along with Shadanga Guggulu for 30 days. The patients were clinically evaluated and observations were recorded as in the case performa. Shamananga Sneha (Guggulu Tiktaka Ghrita) along with Shadanga Guggulu i.e. group B was more beneficial in relieving the symptoms than Shamananga Sneha i.e. group A (Guggulu Tiktaka Ghrita).","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130142647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Plants are among the richest sources of bioactive compounds throughout the world for thousands of years and continue to provide new remedies to mankind. Roots of Hemidesmus indicus R. Br. is an important plant drug which is used to cure leprosy, leucoderma, itching, skin disease, asthma, bronchitis, leucorrhoea, dysentery, piles, syphilis, paralysis, urinary disorders and diabetes mellitus. As per Acharya Charaka has mentioned suitable season for collection of Moola i.e. Greeshma and Shishira Rutu. Here an attempt to study to check the potency of root collected as per classical reference. The present study focused on the pharmacognostical, phytochemical investigation as well as HPLC study were performed by taking different solvent extracts of Hemidesmus indicus root. This study highlights the detailed HPLC study on Hemidesmus indicus root by taking different solvent extracts with their increasing polarity which is a referential information for identification parameters and improves our confidence level of acceptability of herbal drugs.
{"title":"Phyto-pharmacognostic evaluation and HPLC study on Sariva (Hemidsmus indicus R.Br) Root","authors":"K. Kała, Veena Ms, Prabhavathi","doi":"10.21760/jaims.5.5.23","DOIUrl":"https://doi.org/10.21760/jaims.5.5.23","url":null,"abstract":"Plants are among the richest sources of bioactive compounds throughout the world for thousands of years and continue to provide new remedies to mankind. Roots of Hemidesmus indicus R. Br. is an important plant drug which is used to cure leprosy, leucoderma, itching, skin disease, asthma, bronchitis, leucorrhoea, dysentery, piles, syphilis, paralysis, urinary disorders and diabetes mellitus. As per Acharya Charaka has mentioned suitable season for collection of Moola i.e. Greeshma and Shishira Rutu. Here an attempt to study to check the potency of root collected as per classical reference. The present study focused on the pharmacognostical, phytochemical investigation as well as HPLC study were performed by taking different solvent extracts of Hemidesmus indicus root. This study highlights the detailed HPLC study on Hemidesmus indicus root by taking different solvent extracts with their increasing polarity which is a referential information for identification parameters and improves our confidence level of acceptability of herbal drugs.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131361194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cholelithiasis is a crystalline concretion formed within the gall bladder by accretion of bile components. Cholelithiasis can be considered as Pittashaya Ashmari, but there is no direct reference of this condition available in Ayurveda. In Ayurveda the effective treatment is Paneeya Kshara. Surya and Navasadara Paneeya Kshara is standard one and which is highly effective treatment in the management of Cholelithiasis but, persisting pain, presence of calculi has limited in its use. To overcome the lacunas present study has been carried out. This study was conducted at SJIIM Hospital Bengaluru and total of 40 patients were randomly allotted into two groups namely Group A with trial drug i.e. 2grams each of Narikela Lavana, Navasadara, Yava Kshara orally with Jala once daily in empty stomach in the morning, every day for 28 days and Group B with control drug i.e. 2grams of Surya and Navasadara Paneeya Kshara orally with Narikela Jala once daily in empty stomach in the morning, every day for 28 days. Assessment was made on Subjective and Objective parameters. Observations were made before the treatment and on 15th day and 30th day to know the efficacy of the treatment. The combination of Narikela Lavana, Navasadara Yuktha Yava Kshara showed a positive result.
{"title":"Clinical study to evaluate the effectiveness of Narikela Lavana, Navasadara Yuktha Yavakshara in comparision with Surya and Navasadara Paneeya Kshara in the management of Cholelithiasis","authors":"N. ., Srinivas Masalekar","doi":"10.21760/jaims.5.5.5","DOIUrl":"https://doi.org/10.21760/jaims.5.5.5","url":null,"abstract":"Cholelithiasis is a crystalline concretion formed within the gall bladder by accretion of bile components. Cholelithiasis can be considered as Pittashaya Ashmari, but there is no direct reference of this condition available in Ayurveda. In Ayurveda the effective treatment is Paneeya Kshara. Surya and Navasadara Paneeya Kshara is standard one and which is highly effective treatment in the management of Cholelithiasis but, persisting pain, presence of calculi has limited in its use. To overcome the lacunas present study has been carried out. This study was conducted at SJIIM Hospital Bengaluru and total of 40 patients were randomly allotted into two groups namely Group A with trial drug i.e. 2grams each of Narikela Lavana, Navasadara, Yava Kshara orally with Jala once daily in empty stomach in the morning, every day for 28 days and Group B with control drug i.e. 2grams of Surya and Navasadara Paneeya Kshara orally with Narikela Jala once daily in empty stomach in the morning, every day for 28 days. Assessment was made on Subjective and Objective parameters. Observations were made before the treatment and on 15th day and 30th day to know the efficacy of the treatment. The combination of Narikela Lavana, Navasadara Yuktha Yava Kshara showed a positive result.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116580755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lagerstroemia speciosa (L.) Pers (Hindi - Jarul, Taglog - Banaba) a member of Lythraceae family is found all over India, specially in Bengal, Assam and Deccan Peninsula. The leaves of L. speciosa is widely used for lowering blood sugar levels in Philippines, Japan and Taiwan. Pharmacognostical investigation of leaves of L. speciosa was done by evaluating its morphological, microscopical studies, Physicochemical and phytochemical parameters. Rasa Nirdharana was done. Microscopical study revealed presence of epidermal cells contained clusters of rosette aggregate calcium oxalate crystals and few cells were mucilaginous. Lower epidermis showed the presence of anomocytic stomata. Physical constants of leaf powder showed, loss on drying - 3.8%, total ash - 6.7%, acid insoluble ash - 1.039%, water soluble extractive value - 8.88%, alcohol soluble extractive value - 4.49% and pH - 5.75. Preliminary phytochemical study revealed the presence of alkaloids, flavonoids, saponins, triterpenes, tannins, proteins and iron. Rasa Nirdharana confirmed the leaves are Kashaya in Rasa. The Pharmacognostical study was useful for authentication of leaves of Lagerstoemia speciosa.
{"title":"Phyto Pharmacognostic Study of Lagerstroemia speciosa - An Analytical Study","authors":"J. S. Murthy, B. Lalitha, Aahalya Sharma","doi":"10.21760/jaims.5.5.29","DOIUrl":"https://doi.org/10.21760/jaims.5.5.29","url":null,"abstract":"Lagerstroemia speciosa (L.) Pers (Hindi - Jarul, Taglog - Banaba) a member of Lythraceae family is found all over India, specially in Bengal, Assam and Deccan Peninsula. The leaves of L. speciosa is widely used for lowering blood sugar levels in Philippines, Japan and Taiwan. Pharmacognostical investigation of leaves of L. speciosa was done by evaluating its morphological, microscopical studies, Physicochemical and phytochemical parameters. Rasa Nirdharana was done. Microscopical study revealed presence of epidermal cells contained clusters of rosette aggregate calcium oxalate crystals and few cells were mucilaginous. Lower epidermis showed the presence of anomocytic stomata. Physical constants of leaf powder showed, loss on drying - 3.8%, total ash - 6.7%, acid insoluble ash - 1.039%, water soluble extractive value - 8.88%, alcohol soluble extractive value - 4.49% and pH - 5.75. Preliminary phytochemical study revealed the presence of alkaloids, flavonoids, saponins, triterpenes, tannins, proteins and iron. Rasa Nirdharana confirmed the leaves are Kashaya in Rasa. The Pharmacognostical study was useful for authentication of leaves of Lagerstoemia speciosa.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115534515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prishtavamsha Sandhi (joints of vertebral column) is the Cheshtavantha Prathara (movable and floating) type of joint. Twenty four joints are present in Prishtavamsha (vertebral column). Intervertebral joints are the joints which connect vertebrae to each other consists of cartilaginous joints in between the vertebral bodies and synovial joint between vertebral arches. Sandhigatha Vata (osteo arthritis) is one among the Vatavyadhi, which can affect all joints in the body. Sandhigatha Vata (osteoarthritis) will be dominated with symptoms like pain, swelling and impairment of function. In Sandhigatha Vata (osteoarthritis), destruction occurs in the joints due to aggrevated Vata. But it is not clear about the type of destruction observed in the joints. To rule out the various structural changes observed in the joints of Prishtavamsha (vertebral column) this work is being undertaken. Among 100 patients suffering from Prishtavamsha Sandhigatha Vata (osteoarthritis of vertebral column), all patients showed structural changes, 38% having Intervertebral disc prolapse, 22% having spondylosis, 20% having osteophytes, 8% with Osteosclerosis, 6% having spondylolisthesis, 5% with fractures and 1 with stenosis justifies structural changes (Hanthi Sandhi) occurs in Sandhigatha Vata (osteoarthritis). All patients had pain and restricted movements, 80% patient had swelling which justifies the symptoms of Sandhigatha Vata (osteoarthritis).
{"title":"Analysis of structural changes observed in Prishtavamsha Sandhigatha Vata (osteoarthritis of vertebral column)","authors":"Anju Subhash, K. N.","doi":"10.21760/jaims.5.5.18","DOIUrl":"https://doi.org/10.21760/jaims.5.5.18","url":null,"abstract":"Prishtavamsha Sandhi (joints of vertebral column) is the Cheshtavantha Prathara (movable and floating) type of joint. Twenty four joints are present in Prishtavamsha (vertebral column). Intervertebral joints are the joints which connect vertebrae to each other consists of cartilaginous joints in between the vertebral bodies and synovial joint between vertebral arches. Sandhigatha Vata (osteo arthritis) is one among the Vatavyadhi, which can affect all joints in the body. Sandhigatha Vata (osteoarthritis) will be dominated with symptoms like pain, swelling and impairment of function. In Sandhigatha Vata (osteoarthritis), destruction occurs in the joints due to aggrevated Vata. But it is not clear about the type of destruction observed in the joints. To rule out the various structural changes observed in the joints of Prishtavamsha (vertebral column) this work is being undertaken. Among 100 patients suffering from Prishtavamsha Sandhigatha Vata (osteoarthritis of vertebral column), all patients showed structural changes, 38% having Intervertebral disc prolapse, 22% having spondylosis, 20% having osteophytes, 8% with Osteosclerosis, 6% having spondylolisthesis, 5% with fractures and 1 with stenosis justifies structural changes (Hanthi Sandhi) occurs in Sandhigatha Vata (osteoarthritis). All patients had pain and restricted movements, 80% patient had swelling which justifies the symptoms of Sandhigatha Vata (osteoarthritis).","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"31 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116818464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kāśīśa (Ferrous Sulphate, Fe2SO4.7H20), is among the most commonly used mineral drug in Ayurveda, and has been specifically indicated in Mutrashmari. Urolithiasis, (Mutrashmari in Ayurveda) is the third most common urinary system disorder globally with high recurrence rate. The present study is to determine the underlying mechanism of Kāśīśa Bhasma as lithotriptic drug in animal model. Ethylene glycol (0.75% v/v) induced urolithiasis model was used to study the lithotriptic activity of Kāśīśa Bhasma in Wistar albino rats. 30 rats were divided into five groups and were allocated interventions accordingly. Two trial drug groups were given single and double doses of Kāśīśa Bhasma (150mg/kg and 300mg/kg respectively), and were compared against the standard control group (Tab. Cystone 750mg/kg), administered for 14 days. Relevant biochemical assay and histopathological analysis was done and analysed. In vivo study revealed, Kāśīśa Bhasma administered at 300mg/kg b.w. was associated with better lithotriptic activity. The results showed significant reduction in calcium oxalate deposits in the kidneys, restoring the elevated values of serum Creatinine, BUN, uric acid and urine parameters like calcium, phosphate and oxalate while also maintaining optimal urine pH when compared to negative control. The lithotriptic activity of Kāśīśa Bhasma was found to be corresponding to that of standard drug Tab Cystone.
{"title":"An experimental evaluation of the Lithotriptic Activity of Ayurvedic drug Kāśīśa Bhasma","authors":"Kusuma Tv, Jeevesh Kb, Chaitra Lv","doi":"10.21760/jaims.5.5.28","DOIUrl":"https://doi.org/10.21760/jaims.5.5.28","url":null,"abstract":"Kāśīśa (Ferrous Sulphate, Fe2SO4.7H20), is among the most commonly used mineral drug in Ayurveda, and has been specifically indicated in Mutrashmari. Urolithiasis, (Mutrashmari in Ayurveda) is the third most common urinary system disorder globally with high recurrence rate. The present study is to determine the underlying mechanism of Kāśīśa Bhasma as lithotriptic drug in animal model. Ethylene glycol (0.75% v/v) induced urolithiasis model was used to study the lithotriptic activity of Kāśīśa Bhasma in Wistar albino rats. 30 rats were divided into five groups and were allocated interventions accordingly. Two trial drug groups were given single and double doses of Kāśīśa Bhasma (150mg/kg and 300mg/kg respectively), and were compared against the standard control group (Tab. Cystone 750mg/kg), administered for 14 days. Relevant biochemical assay and histopathological analysis was done and analysed. In vivo study revealed, Kāśīśa Bhasma administered at 300mg/kg b.w. was associated with better lithotriptic activity. The results showed significant reduction in calcium oxalate deposits in the kidneys, restoring the elevated values of serum Creatinine, BUN, uric acid and urine parameters like calcium, phosphate and oxalate while also maintaining optimal urine pH when compared to negative control. The lithotriptic activity of Kāśīśa Bhasma was found to be corresponding to that of standard drug Tab Cystone.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130119376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haridra Khanda is unique classical formulation indicated in Udarda, Shitapitta, Kotha. (Urticarial rashes) Khanda or Granules are a comparatively unusual means of administering drugs that possess an unpleasant taste. Haridra Khanda is classical Ayurvedic medicine and available market. Keeping the issue of palatability and invention of patient friendly dosage form in mind, the efforts was made for preparation of tablet out of classical Ayurvedic formulation - Haridra Khanda. The preparation of Haridra Khanda granules were made by standard operative procedure.Binding agents were added to Haridra Khanda . Haridra Khanda was added to mass mixer to ensure homogeneity and easy mixing of all binding agents. And later this mixture was subjected to single punch tablet machine for preparation of 1000 mg tablet. All the Analytical parameters were passed by the Haridra Khanda tablets. Physician can prescribed the tablets to the patients which feel the powdered dosage uncomfortable. Depending on the Roga and Rogibala, tablets of various sizes can be punched and used clinically. This can work more efficiently in pediatric practice.
{"title":"Pharmaceutical evaluation of Haridra Khanda tablet","authors":"Makrand A. Sonare, Manoja K. Samantaray","doi":"10.21760/jaims.5.5.24","DOIUrl":"https://doi.org/10.21760/jaims.5.5.24","url":null,"abstract":"Haridra Khanda is unique classical formulation indicated in Udarda, Shitapitta, Kotha. (Urticarial rashes) Khanda or Granules are a comparatively unusual means of administering drugs that possess an unpleasant taste. Haridra Khanda is classical Ayurvedic medicine and available market. Keeping the issue of palatability and invention of patient friendly dosage form in mind, the efforts was made for preparation of tablet out of classical Ayurvedic formulation - Haridra Khanda. The preparation of Haridra Khanda granules were made by standard operative procedure.Binding agents were added to Haridra Khanda . Haridra Khanda was added to mass mixer to ensure homogeneity and easy mixing of all binding agents. And later this mixture was subjected to single punch tablet machine for preparation of 1000 mg tablet. All the Analytical parameters were passed by the Haridra Khanda tablets. Physician can prescribed the tablets to the patients which feel the powdered dosage uncomfortable. Depending on the Roga and Rogibala, tablets of various sizes can be punched and used clinically. This can work more efficiently in pediatric practice.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130247119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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