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Effect of Marma Therapy on Sandhigata Vata w.s.r. to Osteoarthritis 中药治疗骨性关节炎的疗效观察
Pub Date : 2020-10-25 DOI: 10.21760/jaims.5.5.9
Urvashi Dighekar, Joshi S.K., K. Vimal
The principal aim of Ayurveda is to maintain and promote positive physical and mental health as well as ensure the prevention of diseases. Sandhigata Vata is the commonest form of articular disorder. It is a type of Vatavyadhi which mainly occurs in Vriddhavastha due to Dhatukshaya, which limits everyday activities such as walking, dressing, bathing etc. It occurs due to change in lifestyle like unsuitable sitting, sleeping, standing and look upwards or obliquely in various professions. Osteoarthritis (OA) is degenerative joint disorder, represents failure of the diarthrodial (movable, synovial lined) joint. OA of the joints comes under the inflammatory group which is almost identical to Sandhigata Vata described in Ayurveda with respect to etiology, pathology, and clinical features. Marma therapy is one which gives instant relief from pain by balancing local Vata and Kapha Dosha without any untoward effects. In the present research work, total 15 diagnosed case of Sandhigata Vata were randomly selected from OPD and IPD of department of Shalya Tantra, Rishikul Campus, Uttarakhand Ayurveda University, Haridwar (U.K.) India, all these patients were treated with the application of Marma therapy. Result was observed on the basis of subjective and objective parameters and analysed statistically. No complications were observed in this clinical study.
阿育吠陀的主要目的是维持和促进积极的身心健康,并确保预防疾病。关节紊乱是关节紊乱最常见的形式。这是一种主要发生在vridhavastha的Vatavyadhi,由于Dhatukshaya,它限制了日常活动,如散步,穿衣,洗澡等。由于生活方式的改变,如不合适的坐姿、睡眠、站立、仰视或斜视等,会发生这种情况。骨关节炎(OA)是一种退行性关节疾病,表现为腹泻(活动、滑膜内衬)关节的衰竭。关节关节炎属于炎性组,在病因、病理和临床特征方面与阿育吠陀中描述的Sandhigata Vata几乎相同。玛玛疗法是一种通过平衡局部Vata和Kapha Dosha而没有任何不良影响的方法,可以立即缓解疼痛。本研究随机选取英国哈里瓦尔北阿育吠陀大学Rishikul校区沙利亚坦陀罗系门诊和门诊共15例诊断为Sandhigata Vata的病例。在印度,所有这些患者都接受了Marma疗法的治疗。根据主客观参数对结果进行观察,并进行统计分析。本临床研究未见并发症。
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引用次数: 0
An open label single arm prospective clinical study in the management of Pakshaghata (CVA due to infarct) with Maharasnadi Kashaya and Shunti Churna Maharasnadi Kashaya和Shunti Churna治疗Pakshaghata(因梗死引起的CVA)的开放标签单臂前瞻性临床研究
Pub Date : 2020-10-25 DOI: 10.21760/jaims.5.5.7
R. Mohandas, Muttappa Totad, B. Vasantha, Sphoorthi Narasimhan
Pakshaghata is one among 80 Vata Namathmaja Vyadhi. In Pakshaghata vitiated Vata resides in one half of body and causes Vishoshana of Sira and Snayu leading to loosening of joints results into manifestation of symptoms like Cheshta Nivrutti, Ruja and Vakstambha. Pakshaghata can be correlated to stroke or CVA. The study aims to evaluate the combined effectiveness of Maharasnadi Kashaya with Shunti Churna as Anupana in management of Pakshaghata (CVA due to infarct). The open label prospective clinical study was conducted among the 32 patients of Pakshaghata by convenient sampling method at a tertiary Hospital Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital, Hassan, Karnataka from December 2018 to December 2019. The effectiveness of the drug showed improvement in primary outcome measures such as Cheshta Nivrutti, Vakstambha and Ruk in subjects of Pakshaghata with p value less than 0.05. In this study, maximum improvement was found in “Ruk” followed by “Cheshta Nivrutti” and then “Vak Stambha”. Hence this drug is more effective in “Saruja Pakshaghata” hence; it showed improvement in the NIH stroke scale parameters with p value less than 0.05. The combined effectiveness of Maharasnadi Kashaya with Shunti Churna as Anupana in management of Pakshaghata (CVA due to Infarct) is proved.
Pakshaghata是80名Vata Namathmaja Vyadhi之一。在Pakshaghata,被破坏的Vata驻留在身体的一半,导致Sira和Snayu的Vishoshana,导致关节松动,导致Cheshta Nivrutti, Ruja和Vakstambha等症状的表现。Pakshaghata可能与中风或CVA有关。本研究旨在评价Maharasnadi Kashaya联合Shunti Churna作为Anupana治疗Pakshaghata(因梗死引起的CVA)的有效性。该开放标签前瞻性临床研究于2018年12月至2019年12月在卡纳塔克邦哈桑阿育吠陀学院三级医院的32名Pakshaghata患者中采用便捷抽样方法进行。该药的有效性显示Pakshaghata受试者的Cheshta Nivrutti、Vakstambha和Ruk等主要结局指标有改善,p值小于0.05。在这项研究中,“Ruk”的改善最大,其次是“Cheshta Nivrutti”,然后是“Vak Stambha”。因此,这种药物在“Saruja Pakshaghata”中更有效;NIH脑卒中量表参数改善,p值小于0.05。证实了Maharasnadi Kashaya联合Shunti Churna作为Anupana治疗Pakshaghata(梗死所致CVA)的有效性。
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引用次数: 0
Physico-Chemical analysis of Gandharvahasta Taila - A Polyherbal formulation 甘达瓦哈塔A复方的理化分析
Pub Date : 2020-10-25 DOI: 10.21760/jaims.5.5.36
Sachin Seth, Gangaprasad R. Asore, Vishakha Vivek Sonawane
Sneha Kalpana, a group of medicated Taila and Ghrita is an important dosage form described in Ayurveda. It is the only dosage form that can be administered conveniently both internally and externally depending on the diseased conditions. Among these, Taila Kalpana is considered as the drug of choice for Vatavikaras. Gandharvahasta Taila is mentioned in Ashtanga Sangraha in the context of Vidradhivrudhi Chikitsa indicated in Vidradhi, Pleeha, Vata disorders, etc. Aim: The aim of the study was to prepare and analyze the physicochemical parameters of Gandharvahastadi Taila. Materials and Methods: Gandharvahasta Taila was prepared as per the reference in Ashtanga Sangraha. The obtained product was subjected to organoleptic and physicochemical analysis. Results: Physicochemical parameters obtained are refractive index at 25°C - 1.463, saponification value - 190 mg/g, unsaponifiable matter - 1.4%, specific gravity at 30°C - 0.9201, and viscosity at 30°C - 880cp. Conclusion: The values obtained after analysis were found to be within the permissible limits of API.
Sneha Kalpana,一组药物Taila和Ghrita是阿育吠陀中描述的重要剂型。它是唯一的剂型,可以方便地内外施用取决于疾病的情况。其中,泰拉卡尔帕纳被认为是瓦塔维卡拉的首选药物。在《阿斯汤加圣歌》中,gandhavahasta Taila是在《维拉德、普里哈、瓦塔紊乱》等书中提到的。目的:制备并分析甘达瓦哈帝药材的理化参数。材料与方法:根据《阿斯汤加僧经》的参考文献制备。所得产物进行了感官和理化分析。结果:得到的理化参数为折射率25℃- 1.463,皂化值- 190 mg/g,不皂化物- 1.4%,比重30℃- 0.9201,粘度30℃- 880cp。结论:经分析所得值均在原料药允许范围内。
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引用次数: 0
To assess the importance of Nidana Parivarjan in the treatment of Urdhvag Amlapitta with Guduchi Satva 评估禅定禅定在古都齐禅定治疗Urdhvag Amlapitta中的重要性
Pub Date : 2020-09-20 DOI: 10.21760/JAIMS.5.4.3
Parag Kulkarni, Mangesh Jagannath Thamake
Amlapitta is one of the leading clinical conditions in today’s speedy lifestyle. Present study focuses on this burning issue and its causes mentioned in Ayurved texts and actual causes observed in day to day life. Importance and benefits of Nidanparivarjan over only symptomatic treatment was assessed during this study. Amlapitta cases were diagnosed according to Ayurvedic texts and classified into two groups. One group was administered with only treatment and the other group was advised Nidanparivarjan along with the treatment. At the end of the study, it was found that the group with Nidanparivarjan was more benefited as compared to only treatment group. This clearly states that Ayurvedic method of finding the particular Hetu of the disease and practice of avoiding those Hetu; i.e. Nidanparivarjan leads to better results and complete eradication and prevention of the disease; thus serving the main principle of Ayurved science - Prevention is better than Cure.
Amlapitta是当今快速生活方式中的主要临床病症之一。目前的研究集中在这个燃烧的问题和它的原因提到的阿育文本和实际原因观察到的日常生活。在本研究中评估了Nidanparivarjan相对于仅对症治疗的重要性和益处。根据阿育吠陀文献诊断Amlapitta病例并分为两组。一组只给予治疗,另一组在治疗的同时给予Nidanparivarjan。在研究结束时,发现与仅治疗组相比,使用Nidanparivarjan的组受益更多。这清楚地说明,阿育吠陀的方法发现了特定的赫图人的疾病,并避免了那些赫图人的做法;即,Nidanparivarjan带来更好的结果,彻底根除和预防该疾病;因此服务于中医科学的主要原则——预防胜于治疗。
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引用次数: 1
Combined effectiveness of Maharasnadi Kashaya with Shunti Churna and Matra Basti with Ksheerabala Taila in Janu Sandhigata Vata (Osteoarthritis Knee) : An open label, single arm clinical study Maharasnadi Kashaya联合Shunti Churna和Matra Basti联合Ksheerabala Taila治疗膝关节骨性关节炎的疗效:一项开放标签单臂临床研究
Pub Date : 2020-08-25 DOI: 10.21760/jaims.5.4.11
K. Kiran, B. Vasantha, Muttappa Totad
Sandhi Gata Vata is a clinical condition that comes under the heading of Vata Vyadhi where Prakupita Vata affects Sandhi and causes specific signs and symptoms. Lakshanas of Sandhi Gata Vata of Janu Sandhi resembles the signs and symptoms of osteoarthritis of knee. Osteoarthritis of the knee is more commonly found in women than men, and the prevalence increases dramatically with age. The major risk factors associated with osteoarthritis knee joint are old age, obesity, excessive usage of knee joint (occupational), which makes it an important cause of disability. A clinical study was conducted on 31 subjects by administering combination of Maharsnadi Kashaya with Shunti Churna and Matra Basti with Ksheerabala Taila and the results obtained were statistically analysed. Statistically significant reduction in Lakshanas of Janu Sandhi Gata Vata and WOMAC scores were noted.
Sandhi Gata Vata是一种临床病症,属于Vata Vyadhi的标题,Prakupita Vata影响Sandhi并引起特定的体征和症状。Lakshanas的Sandhi Gata Vata的Janu Sandhi类似于膝关节骨关节炎的症状和体征。膝骨关节炎在女性中比男性更常见,患病率随着年龄的增长而急剧增加。与膝关节骨关节炎相关的主要危险因素是老年、肥胖、过度使用膝关节(职业性),这使其成为致残的重要原因。采用Maharsnadi Kashaya联合Shunti Churna、Matra Basti联合Ksheerabala Taila对31例患者进行临床研究,并对所得结果进行统计分析。注意到Janu Sandhi Gata Vata和WOMAC评分的Lakshanas在统计上显着降低。
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引用次数: 0
Clinical study to evaluate the effectiveness of Gavakshi Moola (Citrullus colocynthis) Draava with Ksheera in Kamala (hepatocellular jaundice) 肝细胞性黄疸患者卡玛拉(Ksheera)联合加药治疗的临床研究
Pub Date : 2020-08-25 DOI: 10.21760/jaims.5.4.5
M. -, Lakshmiprasad L. Jadhav
Hepatocellular jaundice is a sign that usually accompanies diseases of liver, the organ that detoxifies metabolites, synthesizes proteins, produces biochemicals necessary for digestion, decomposes red blood cells and produces hormones,[1] hence is constantly under the risk of various diseases. Causes of hepatocellular jaundice are numerous with the most common being viral hepatitis, alcohol and drug toxicity. Kamala described among the Pittaja Nanatmaja Vyadhi has Haridra Varna of Netra, Twak, Nakha, Anana, Mutra as the cardinal sign, hence analogous to jaundice. The administration of Gavakshimoola Draava for 3 days is described in the management of Kamala. A clinical trial was conducted on 15 subjects and the results obtained were statistically analysed. Statistically significant reduction of Lakshana of Kamala and serum levels of bilirubin with p-value less than 0.05 was noted.
肝细胞性黄疸是肝脏疾病的常见症状,肝脏是解毒代谢物、合成蛋白质、产生消化所需生化物质、分解红细胞、产生激素的器官[1],因此不断处于各种疾病的危险之中。肝细胞性黄疸的原因很多,最常见的是病毒性肝炎、酒精和药物毒性。在Pittaja Nanatmaja Vyadhi中,Kamala描述了Netra, Twak, Nakha, Anana, Mutra的Haridra Varna作为主要标志,因此类似于黄疸。在Kamala的管理中描述了Gavakshimoola Draava为期3天的管理。对15名受试者进行了临床试验,并对试验结果进行了统计分析。血清胆红素水平和卡玛拉指数降低,p值< 0.05,有统计学意义。
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引用次数: 0
An experimental evaluation of Vishagna (Alstonia venenata R. Br.) a folk medicinal plant for anticonvulsant activity in Swiss Albino Mice 瑞士白化病小鼠抗惊厥作用的实验评价
Pub Date : 2020-08-25 DOI: 10.21760/jaims.5.4.13
Anusha Pr, Chandrakanth Bhat, H. Shetty, Sudhakara Bhat
Back ground: Epilepsy describes a condition in which a person has recurrent seizures due to a chronic, underlying process. Globally, it is the third most common neurological disorder. There is still a need for an ideal anticonvulsant agent with broad spectrum activity, rapid onset of action, least side effects, good bio availability and low cost. Materials and Methods: Vishagna (Alstonia venenata R. Br.) belonging to Apocynaceae family is an ethno medicinal plant; the stem bark of the plant is used as antiepileptic drug among tribes. This study aims to experimentally evaluate anticonvulsant activity of the drug in PTZ induced generalized seizures and kindling on Swiss albino mice. The acute oral toxicological evaluation of the drug was conducted prior to the anticonvulsant study. Result and Conclusion: Result of the toxicological study reveals that the drug is relatively safe to be used as medicine. The data of the experimental study shows that the drug is moderate to highly effective anticonvulsant in PTZ induced generalized seizures and is mild-moderately helpful in controlling the development of kindled seizures in mice. It also shows that the drug imparts protective action against a sub convulsive dose of PTZ in kindling by inhibiting epileptogenesis and development of potential seizure threshold even when the disease was fully developed.
背景:癫痫是指一个人由于慢性的潜在过程而反复发作的一种疾病。在全球范围内,它是第三大最常见的神经系统疾病。目前仍需要一种具有广谱活性、起效快、副作用小、生物利用度好、成本低的理想抗惊厥药。材料与方法:天麻属夹竹桃科,是一种民族药用植物;这种植物的茎皮在部落中被用作抗癫痫药。本研究旨在通过实验评价该药物对PTZ致全身癫痫和瑞士白化小鼠的抗惊厥活性。在抗惊厥药研究之前进行了药物的急性口服毒理学评估。结果与结论:毒理学研究结果表明,该药物可相对安全的作为药物使用。实验研究数据表明,该药物对PTZ引起的全身性癫痫发作具有中效至高效的抗惊厥作用,对控制小鼠点燃性癫痫发作的发展有轻-中度的帮助。它还表明,即使在疾病完全发展时,药物通过抑制癫痫发生和潜在发作阈值的发展,赋予对亚惊厥剂量的PTZ点燃的保护作用。
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引用次数: 0
Knowledge attitude and practice of Peya among practitioners of Ayurveda 阿育吠陀修行者的知识、态度与培亚修行
Pub Date : 2020-08-25 DOI: 10.21760/jaims.5.4.17
Shinitha Pv
Ahara plays an important role in the maintenance of health and cure of diseases. Various dietetic preparations are explained in Ayurveda under Pathya Kalpana. Among this Pathya Kalpana, Peya is most commonly used preparation. No much study is undergone on this topic. Peya is beneficial in healthy and diseased. Peya is Satmya to people living in southern parts of India. So medicines can be administered by adding it with Peya. In classics, there are various diseases in which Peya have been recommended. On administering Oushada Siddha Peya in these conditions Peya does its action as well as exhibits the properties of Dravyas with which it is processed. It cures disease and at the same time nourishes Dhathus. A KAP survey was conducted as a part of study among the Ayurvedic practitioners. Majority of practitioners were found to administer classical Peya Yogas. Utility of Peya have been extended to other diseases, which are not mentioned in classical ayurvedic text books. This proves that Peya can be administered depending on the condition of patient as well as stage of disease. It was observed from the study that 78.0% practitioners had good knowledge regarding Peya and more than 50.0% had positive attitude towards this treatment modality. But only 46.0% practitioners adopted Oushada Siddha Peya in their practice.
原在保持健康和治疗疾病方面起着重要作用。阿育吠陀在Pathya Kalpana下解释了各种各样的饮食准备。在这些帕提亚卡尔帕纳中,佩亚是最常用的制剂。在这个问题上没有进行太多的研究。佩亚对健康和疾病都有益。对生活在印度南部地区的人来说,佩亚是Satmya。所以药物可以通过加入Peya来给药。在经典中,有各种疾病都推荐了培牙。在这些条件下管理奥沙达悉达佩亚时,佩亚不仅表现出被处理的吠陀的属性,而且也表现出它的行为。它能治疗疾病,同时也能滋养禅。KAP调查作为阿育吠陀从业者研究的一部分进行。大多数练习者被发现练习经典的佩亚瑜伽。Peya的效用已经扩展到其他疾病,这些疾病在经典的阿育吠陀教科书中没有提到。这证明佩亚可以根据病人的情况和疾病的阶段来给药。研究发现,78.0%的医生对培雅有良好的认识,50.0%以上的医生对培雅有积极的态度。但只有46.0%的练习者在他们的实践中采用了奥沙达悉达佩亚。
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引用次数: 0
A comparative clinical study on the efficacy of Nasya with Pinyaka / Panchamula Taila and Swalpa Masha Taila in Apabahuka w.s.r. to frozen shoulder Apabahuka w.s.r.的Nasya与Pinyaka / Panchamula Taila和Swalpa Masha Taila治疗肩周炎疗效的比较临床研究
Pub Date : 2020-08-25 DOI: 10.21760/jaims.5.4.6
Conception Costa, S. A., Jeejo Chandran O
Background: Apabahuka is a Vataja Nanatmaja Vyadhi, in which locomotive functions of Amsa Sandhi are affected mainly due to Vata Dosha Prakopa causing pain, stiffness and restricted movement of the shoulder. Apabahuka can be correlated to Frozen shoulder or Adhesive Capsulitis in modern medicine because of similar symptomatology. Nasya is indicated in Urdhwajatrugata Vikaras. Pinyaka Taila and Swalpa Masha Taila are Vatahara Taila used for Nasya. Method: A single blind randomised clinical study in which 40 clinically diagnosed patients of Apabahuka, fulfilling the inclusion criteria were selected and divided into two groups - Group A treated with Pinyaka / Panchamula Taila Nasya and Group B treated with Swalpa Masha Taila Nasya, comprising of 20 patients each. Result: Statistically Nasya with Pinyaka Taila showed better results in Pain (51.2%), Stiffness (48%), Tenderness (58.33%), with improvement in goniometric readings of shoulder ROM than Nasya with Swalpa Masha Taila in Pain (39.4%), stiffness (40.9%), Tenderness (58%). Discussion: Rukshadi Gunas of Vata are increased in Apabahuka hence Viparita Gunas like Snigdhadi in the form of Brumhana Nasya with Pinyaka Taila was found to be effective in Apabahuka. In the present study Group A Nasya with Pinyaka Taila showed better effect than Group B Nasya with Swalpa Masha Taila.
背景:Apabahuka是一种Vataja Nanatmaja Vyadhi,其中Amsa Sandhi的运动功能主要是由于Vata Dosha Prakopa引起肩部疼痛、僵硬和运动受限而受到影响。在现代医学中,Apabahuka可与肩周炎或粘连性囊炎相关联,因为它们具有相似的症状。Nasya在Urdhwajatrugata Vikaras中表示。Pinyaka Taila和Swalpa Masha Taila是Vatahara Taila用于Nasya。方法:选择40例符合纳入标准的临床诊断为Apabahuka的患者进行单盲随机临床研究,将其分为两组,A组使用Pinyaka / Panchamula Taila Nasya治疗,B组使用Swalpa Masha Taila Nasya治疗,每组20例。结果:在疼痛(51.2%)、僵硬(48%)、压痛(58.33%)方面,Pinyaka Taila治疗组的疗效优于Swalpa Masha Taila治疗组,肩关节ROM的角度读数改善(39.4%)、僵硬(40.9%)、压痛(58%)。讨论:Vata的Rukshadi Gunas在Apabahuka中增加,因此Viparita Gunas如Snigdhadi以Brumhana Nasya的形式与Pinyaka Taila在Apabahuka中被发现是有效的。在本研究中,A组患儿用Pinyaka Taila治疗的效果优于B组患儿用Swalpa Masha Taila治疗。
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引用次数: 0
A study of the combined effect of Nasya Karma and Yoga techniques in Manyasthambha w.s.r. to Cervical Spondylosis 颈椎病的颈椎病的综合效果的研究,在许多asashambha瑜伽技术
Pub Date : 2020-08-25 DOI: 10.21760/jaims.5.4.1
Veena S. Pattar, Prasanna Kulkarni, Prabhu C Nagalapur, Vinod Akkasali
In today’s modern competitive world, people are oriented towards white collar jobs, use of computer and thus prone more to develop Manyasthambha which is an emerging morbidity in society. Manyasthambha is one of the Vataja Nanatmaja Vyadhi with symptoms such as pain and stiffness is pacified through Vata Kapha management. It can be correlated to cervical spondylosis which is commonly seen in middle and elderly population. About 85% of males and 60-70% of the females shows degenerative changes leading to cervical spondylosis. Anti inflammatory, Analgesic is the drugs of choice in contemporary system of medicine. But all the analgesic is liable to cause many side effects particularly by repeated and prolonged usage. Ayurveda the age-old Indian system of medicine advocates a reliable management of Manyasthambha. Nasya is believed to have a note worthy role in relieving pain and stiffness within the cardinal feature of Manyasthambha. Yogasanas also help in relieving neck pain and stiffness around spine and strengthens, increases flexibility of the spine and para-spinal muscles. It increases blood circulation and reduces compression in nerve. Therefore, this study has been undertaken as an attempt to help the patients suffering from Manyasthambha in our society and also to evaluate the efficacy of these treatment modalities.
在当今现代竞争激烈的世界中,人们都倾向于白领工作,使用电脑,因此更容易发展多病,这是一种新兴的社会发病率。manyasasambha是Vataja Nanatmaja Vyadhi的一种,通过Vata Kapha管理可以缓解疼痛和僵硬等症状。可能与中老年人群常见的颈椎病有关。约85%的男性和60-70%的女性表现为退行性改变,导致颈椎病。抗炎、镇痛药是现代医学体系的首选药物。但所有的镇痛药都容易引起许多副作用,特别是反复和长期使用。古老的印度医学体系阿育吠陀提倡对许多哮喘的可靠管理。在manyasasambha的基本特征中,Nasya被认为在缓解疼痛和僵硬方面具有值得注意的作用。瑜伽体式也有助于缓解颈部疼痛和脊柱周围的僵硬,增强脊柱和脊柱旁肌肉的灵活性。它能促进血液循环,减少神经压迫。因此,这项研究是为了帮助我们社会中患有许多哮喘的患者,并评估这些治疗方式的疗效。
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引用次数: 0
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Journal of Ayurveda and Integrated Medical Sciences (JAIMS)
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