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A home-based telehealth randomized controlled trial of skills training in affective and interpersonal regulation versus present-centered therapy for women veterans who have experienced military sexual trauma. 一项以家庭为基础的远程医疗随机对照试验,针对经历过军队性创伤的女性退伍军人进行情感和人际关系调节方面的技能培训与以现在为中心的治疗。
IF 4.5 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-05-01 Epub Date: 2024-01-15 DOI: 10.1037/ccp0000872
Marylene Cloitre, Danielle Morabito, Kathryn Macia, Sarah Speicher, Jessilyn Froelich, Katelyn Webster, Annabel Prins, Diana Villasenor, Asha Bauer, Christie Jackson, Laura Fabricant, Shannon Wiltsey-Stirman, Leslie Morland

Objective: This randomized trial tested the effectiveness of Skills Training in Affective and Interpersonal Regulation (STAIR) compared to present-centered therapy (PCT) delivered virtually to women veterans who had experienced military sexual trauma (MST) and screened positive for posttraumatic stress disorder (PTSD).

Method: One hundred sixty-one eligible women veterans were randomized into the study. The primary outcome was clinician-assessed PTSD severity (Clinician-Administered PTSD Scale-5), while secondary outcomes included social support and several other symptom measures at posttreatment through 2- and 4-month follow-up.

Results: PTSD severity decreased in both conditions by posttreatment but significantly more (p = .028, d = 0.39) in STAIR (d = 1.12 [0.87, 1.37]) than PCT (d = .78 [0.54, 1.02]). STAIR was also superior in improving social support and emotion regulation and reducing depression and negative cognitions. Improvement in psychosocial functioning was moderate and did not differ between conditions. All changes were maintained through 2- and 4-month follow-ups. Dropout rates were low and did not differ (19.0% and 12.2%, respectively).

Conclusion: STAIR provided superior outcomes compared to PCT regarding PTSD, social support, and multiple types of mental health problems among women veterans with MST. The application of STAIR to other populations with social support and related concerns warrants investigation. The substantial effect sizes for PTSD symptoms in both treatments suggest that they are practical alternatives for individuals who do not wish to participate in trauma-focused therapy and may increase engagement in mental health services. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

试验目的这项随机试验测试了情感和人际关系调节技能培训(STAIR)与当前中心疗法(PCT)的有效性比较,后者是以虚拟方式提供给经历过军队性创伤(MST)并筛查出创伤后应激障碍(PTSD)的女性退伍军人:方法:161 名符合条件的女性退伍军人被随机纳入研究。主要结果是临床医生评估的创伤后应激障碍严重程度(临床医生管理的创伤后应激障碍量表-5),次要结果包括治疗后 2 个月和 4 个月随访期间的社会支持和其他一些症状测量:治疗后,两种情况下的创伤后应激障碍严重程度都有所下降,但 STAIR(d = 1.12 [0.87, 1.37])的下降幅度(p = .028,d = 0.39)明显高于 PCT(d = .78 [0.54, 1.02])。STAIR 在改善社会支持和情绪调节、减少抑郁和消极认知方面也更胜一筹。社会心理功能的改善程度适中,在不同条件下没有差异。所有的变化都在 2 个月和 4 个月的随访中得以保持。辍学率较低且无差异(分别为 19.0% 和 12.2%):结论:与 PCT 相比,STAIR 在创伤后应激障碍、社会支持以及患有创伤后应激障碍的女性退伍军人的多种心理健康问题方面提供了更好的结果。将 STAIR 应用于其他有社会支持和相关问题的人群值得研究。这两种治疗方法对创伤后应激障碍症状的显著效果表明,对于那些不愿意参加以创伤为中心的治疗的人来说,这两种治疗方法是切实可行的替代疗法,而且可以提高心理健康服务的参与度。(PsycInfo Database Record (c) 2024 APA,保留所有权利)。
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引用次数: 0
Psychotherapies for the treatment of borderline personality disorder: A systematic review. 边缘型人格障碍的心理治疗:一项系统综述。
IF 4.5 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-05-01 Epub Date: 2023-10-30 DOI: 10.1037/ccp0000833
Karen Crotty, Meera Viswanathan, Sara Kennedy, Mark J Edlund, Rania Ali, Mariam Siddiqui, Roberta Wines, Piotr Ratajczak, Gerald Gartlehner

Objective: Borderline personality disorder (BPD) is the most common personality disorder, affecting 1.8% of the general population, 10% of psychiatric outpatients, and 15%-25% of psychiatric inpatients. Practice guidelines recommend psychotherapies as first-line treatments. However, psychotherapies commonly used for the treatment of BPD are numerous, and little is known about the comparative effectiveness of each individual psychotherapy versus treatment as usual (TAU) or other psychotherapies. To systematically assess the comparative effectiveness of commonly used psychotherapies versus TAU or versus other psychotherapies for BPD treatment.

Method: We conducted systematic literature searches in MEDLINE, EMBASE, the Cochrane Library, and APA PsycINFO up to July 14, 2022, and searched reference lists of pertinent articles and reviews. Inclusion criteria were (a) patients 13 years or older with a diagnosis of BPD, (b) treatment with commonly used psychotherapies, (c) comparison with TAU or another psychotherapy, (d) assessment of relevant BPD-related health outcomes, and (e) randomized or nonrandomized trials or controlled observational studies. Two investigators independently screened abstracts and full-text articles and graded the certainty of evidence using the Grading of Recommendations Assessment, Development, and Evaluation approach.

Results: We found 25 psychotherapy studies meeting inclusion criteria with data on 2,545 participants. Seventeen studies compared nine psychotherapies with TAU and nine studies compared eight psychotherapies with another psychotherapy for the treatment of BPD. Overall, both TAU and included psychotherapies were effective in treating the severity and symptoms of BPD. Moderate certainty of evidence suggests that systems training for emotional predictability and problem solving is more effective than TAU for the treatment of BPD; low certainty of evidence suggests that dialectical behavior therapy, schema therapy, transference-focused psychotherapy, acceptance and commitment therapy, manual-assisted cognitive therapy, and cognitive behavioral therapy are more effective than TAU for treating BPD. We were unable to draw conclusions from head-to-head comparisons of psychotherapies, which were limited to single studies with very low to low certainty of evidence.

Conclusions: All commonly used psychotherapies improve BPD severity, symptoms, and functioning. Our assessment found no strong evidence suggesting that any one psychotherapy is more beneficial than another. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

目的:边缘型人格障碍(BPD)是最常见的人格障碍,影响1.8%的普通人群、10%的精神科门诊患者和15%-25%的精神科住院患者。实践指南建议将心理治疗师作为一线治疗方法。然而,通常用于治疗BPD的心理治疗师有很多,而且对每种个体心理治疗与常规治疗(TAU)或其他心理治疗师的比较有效性知之甚少。系统评估常用心理治疗师与TAU或其他心理治疗师治疗BPD的比较有效性。方法:截至2022年7月14日,我们在MEDLINE、EMBASE、Cochrane图书馆和APA PsycINFO进行了系统的文献检索,并检索了相关文章和综述的参考文献列表。纳入标准为(a)13岁或以上诊断为BPD的患者,(b)常用心理治疗师的治疗,(c)与TAU或其他心理治疗的比较,(d)评估相关BPD相关的健康结果,以及(e)随机或非随机试验或对照观察性研究。两名研究人员独立筛选了摘要和全文文章,并使用建议分级评估、发展和评估方法对证据的确定性进行了分级。结果:我们发现25项心理治疗研究符合纳入标准,数据涉及2545名参与者。17项研究将9种心理治疗师与TAU进行了比较,9项研究将8种心理疗法与另一种治疗BPD的心理疗法进行了比较。总体而言,TAU和纳入的心理治疗师在治疗BPD的严重程度和症状方面都是有效的。适度的证据确定性表明,在治疗BPD方面,情绪可预测性和问题解决的系统训练比TAU更有效;证据的低确定性表明,辩证行为疗法、图式疗法、移情心理治疗、接受和承诺疗法、手动辅助认知疗法和认知行为疗法在治疗BPD方面比TAU更有效。我们无法从心理治疗师的正面比较中得出结论,这些比较仅限于证据确定性非常低的单一研究。结论:所有常用的心理治疗师都能改善BPD的严重程度、症状和功能。我们的评估没有发现强有力的证据表明任何一种心理治疗都比另一种更有益。(PsycInfo数据库记录(c)2023 APA,保留所有权利)。
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引用次数: 0
What works better? 1-year outcomes of an effectiveness trial comparing online, telehealth, and group-based formats of a military parenting program. 哪种方法更有效?比较在线、远程医疗和基于小组形式的军事育儿计划的有效性试验的 1 年结果。
IF 4.5 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-05-01 Epub Date: 2024-03-28 DOI: 10.1037/ccp0000882
Abigail H Gewirtz, David S DeGarmo, Susanne Lee

Objective: The present study, conducted with a population of military families, examined the comparative effectiveness of three program formats of Adaptive Parenting Tools (ADAPT), a parenting program for families of school-aged children in which a National Guard or Reserve (NG/R) parent had returned from deployment to the post-9/11 conflicts. Despite well-documented need, parenting programs for NG/R families are scarce and often inaccessible. We predicted that both facilitator-delivered conditions (i.e., in-person group; individual telehealth) would result in stronger improvements in observed parenting than assignment to the online self-directed condition. We further proposed a noninferiority hypothesis wherein no significant difference would be detected between telehealth and group conditions.

Method: Families (N = 244; 87% Caucasian) were recruited from NG/R units in two midwestern states. Families (with a 5-12-year-old child) were randomized to one of three conditions: in-person multifamily group, individual telehealth, or an online, self-directed condition. The intervention was delivered using the same content across conditions, over 14 weeks (group, telehealth conditions) or 12 modules (online condition); either or both parents could participate.

Results: Intent-to-treat analyses supported both hypotheses: families in both in-person group and telehealth conditions showed significant improvements to observed parenting at 1-year postbaseline compared with those assigned to the self-directed online condition.

Conclusions: This is the first study to demonstrate that in-person group and telehealth parenting programs are equally effective and that both are superior to a self-directed online program. Limitations include differences between the session lengths in each format, as well as greater attrition in the in-person format. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

研究目的本研究以军人家庭为对象,考察了 "适应性育儿工具"(ADAPT)三种计划形式的比较效果。"适应性育儿工具 "是一项针对国民警卫队或后备役(NG/R)军人家庭的育儿计划,其对象是在 9/11 后冲突中服役归来的学龄儿童。尽管需求已得到充分证实,但针对 NG/R 家庭的育儿计划却很少,而且往往难以获得。我们预测,两种由辅导员提供的条件(即面对面小组辅导;个人远程保健)都会比分配到在线自我指导条件下更能改善所观察到的养育情况。我们还提出了一个非劣效性假设,即在远程保健和小组条件之间不会发现显著差异:从美国中西部两个州的 NG/R 单位招募家庭(N = 244;87% 为白种人)。家庭(有一个 5-12 岁的孩子)被随机分配到三种条件之一:面对面多家庭小组、个人远程保健或在线自我指导条件。不同条件下的干预采用相同的内容,为期 14 周(小组、远程保健条件)或 12 个模块(在线条件);父母双方或其中一方均可参与:结果:意向治疗分析支持了两个假设:与那些被分配到自我导向在线条件下的家庭相比,在基线后 1 年,参加面对面小组和远程保健条件的家庭在观察到的养育方面都有显著改善:这是第一项证明面对面小组和远程保健育儿计划同样有效,并且都优于自主在线计划的研究。研究的局限性包括两种形式的疗程长短不同,以及面对面形式的损耗更大。(PsycInfo Database Record (c) 2024 APA, 版权所有)。
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引用次数: 0
Testing psychosocial interventions in context: Commentary on Beidas et al. (2023). 测试背景下的社会心理干预:对 Beidas 等人(2023 年)的评论。
IF 4.5 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-05-01 DOI: 10.1037/ccp0000877
Kenneth E Freedland, Lynda H Powell, Susan M Czajkowski, Leonard H Epstein

In their recent Viewpoint article, Beidas et al. (2023) argue that researchers should test psychosocial interventions in the contexts in which they are meant to be delivered and that they can accelerate the deployment of these interventions by advancing directly from pilot trials to effectiveness and implementation studies without conducting efficacy trials. In this commentary, we argue that this is a well-intended but problematic approach and that there is a more productive strategy for translational behavioral intervention research. The commentary discusses issues concerning intervention development, refinement, and optimization; pilot and efficacy testing of interventions; the contexts in which interventions are delivered; clinical practice guidelines; and quick versus programmatic answers to significant clinical research questions. Testing psychosocial interventions in the contexts in which they are meant to be delivered is a complex task for interventions that are designed to be used in a wide variety of contexts. Nevertheless, interventions can be tested in the contexts in which they are meant to be delivered without sacrificing programmatic intervention development or safety and efficacy testing. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Beidas等人(2023年)在最近发表的《观点》文章中认为,研究人员应该在社会心理干预措施的实施环境中对其进行测试,他们可以不进行疗效试验,直接从试点试验推进到有效性和实施研究,从而加快这些干预措施的部署。在这篇评论中,我们认为这种方法的初衷是好的,但却存在问题,还有一种更有成效的转化行为干预研究策略。本评论讨论了有关干预措施的开发、改进和优化;干预措施的试验和疗效测试;实施干预措施的环境;临床实践指南;以及对重大临床研究问题的快速回答与方案回答等问题。对于设计用于各种环境的干预措施来说,在干预措施的实施环境中测试社会心理干预措施是一项复杂的任务。尽管如此,在不影响干预项目开发或安全性和有效性测试的前提下,可以在干预措施的实施环境中对其进行测试。(PsycInfo Database Record (c) 2024 APA, 版权所有)。
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引用次数: 0
Advancing a mission of translational intervention science: Comment on premature implementation. 推进转化干预科学的使命:关于过早实施的评论。
IF 4.5 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-05-01 DOI: 10.1037/ccp0000885
Rinad S Beidas, Lisa Saldana, Rachel C Shelton

Replies to comments made by Kenneth E. Freedland et al. (see record 2024-89430-002) on Rinad S. Beida, Lisa Saldana, and Rachel C. Shelton's original article (see record 2023-46817-001). In reading Freedland et al.'s (2024) commentary, it appears that their lens prioritizes internal validity and more explanatory and mechanistic work. While we also value these scientific goals and concur that the approaches they identify are clearly methodologically rigorous, we do not think the approaches will substantially reduce the unacceptable translation gap or address the fundamental issues of context. Our approach recognizes that there is tremendous value in cocreating solutions and interventions with patients, clinicians, and community members in the settings where we are seeking to promote health and address health inequities, and questions traditional assumptions and paradigms that scientists "know best" have effective solutions or should hold all of the power and knowledge (Brownson et al., 2022; Sanchez et al., 2023; Shelton, Adsul, & Oh, 2021; Shelton, Adsul, Oh, et al., 2021). We believe it is critical that we expand the pathways through which we advance intervention science in a meaningful and impactful way, and with more explicit attention to issues of context, equity, engagement, and external validity. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

答复肯尼斯-E-弗里德兰等人(见记录 2024-89430-002)对 Rinad S. Beida、Lisa Saldana 和 Rachel C. Shelton 的原始文章(见记录 2023-46817-001)的评论。在阅读弗里德兰等人(2024)的评论时,他们的视角似乎优先考虑内部有效性以及更具解释性和机制性的工作。虽然我们也重视这些科学目标,并同意他们所确定的方法显然在方法论上是严谨的,但我们并不认为这些方法能大幅缩小不可接受的转化差距或解决背景的根本问题。我们的方法认识到,在我们寻求促进健康和解决健康不平等问题的环境中,与患者、临床医生和社区成员共同创造解决方案和干预措施具有巨大价值,并质疑科学家 "最了解 "有效解决方案或应掌握所有权力和知识的传统假设和范式(Brownson 等人,2022 年;Sanchez 等人,2023 年;Shelton、Adsul 和 Oh,2021 年;Shelton、Adsul、Oh 等人,2021 年)。我们认为,至关重要的是,我们要拓展途径,以有意义、有影响的方式推进干预科学的发展,并更明确地关注背景、公平、参与和外部有效性等问题。(PsycInfo Database Record (c) 2024 APA,保留所有权利)。
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引用次数: 0
Dose-response relationship in cognitive behavioral therapy for depression: A nonlinear metaregression analysis. 抑郁症认知行为疗法的剂量-反应关系:非线性元回归分析
IF 5.9 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-05-01 DOI: 10.1037/ccp0000879
Thomas Klein, Johanna Breilmann, Carolin Schneider, Francesca Girlanda, Ines Fiedler, Sarah Dawson, Alessio Crippa, Stefan Priebe, Corrado Barbui, Thomas Becker, Markus Kösters

Objective: Evidence on the optimal "dose" of cognitive behavioral therapy (CBT) for treating major depressive disorder is sparse. This analysis aimed to evaluate the dose-response curve in CBT using a nonlinear approach, whereby "dose" was defined as number of treatment sessions. The dose-response curve of CBT was compared to other psychotherapies and pharmacological treatments for depression.

Method: A systematic review and metaregression analysis of randomized controlled trials (RCTs) examining the efficacy of CBT in adults with acute depression was conducted. Treatment arms examining other psychosocial or pharmacological interventions were also analyzed. Cubic spline metaregression techniques were used to model nonlinear dose-response curves.

Results: Seventy-two studies and 7,377 participants were included. Modeling the dose-response curve between change of depression symptom severity and the number of CBT sessions resulted in a nonlinear curve characterized by a strong improvement in symptom severity from baseline within the first eight sessions. Symptom reduction continues in the further course of the treatment, but at a slower pace. A similar pattern of symptom development was found for other therapies as well, although the prominence of early improvement and overall effect sizes vary across treatment arms.

Conclusion: Results imply a general tendency for the strongest alleviation of depressive symptom severity in early stages of CBT treatment, thus, if aiming at symptom alleviation, speak for short CBT interventions. However, these findings have to be discussed in the light of the limited data regarding the sustainability of treatment effects in short-term therapies and effects beyond symptomatic changes. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

目的:关于认知行为疗法(CBT)治疗重度抑郁障碍的最佳 "剂量 "的证据并不多。本分析旨在使用非线性方法评估 CBT 的剂量-反应曲线,其中 "剂量 "被定义为治疗次数。将 CBT 的剂量-反应曲线与其他抑郁症心理疗法和药物疗法进行比较:方法:我们对随机对照试验(RCT)进行了系统回顾和元回归分析,研究了 CBT 对成人急性抑郁症患者的疗效。此外,还分析了研究其他社会心理或药物干预措施的治疗臂。立方样条元回归技术用于模拟非线性剂量-反应曲线:结果:共纳入 72 项研究和 7377 名参与者。建立抑郁症状严重程度变化与 CBT 治疗次数之间的剂量-反应曲线模型后,得出了一条非线性曲线,其特点是在最初的 8 次治疗中,症状严重程度与基线相比有很大改善。在接下来的治疗过程中,症状会继续减轻,但速度会放慢。其他疗法也发现了类似的症状发展模式,但不同疗法的早期改善程度和总体效果大小各不相同:结论:研究结果表明,CBT 治疗早期对抑郁症状严重程度的缓解作用最强,因此,如果以缓解症状为目标,应采用短期 CBT 干预疗法。不过,在讨论这些研究结果时,必须考虑到有关短期疗法疗效的可持续性以及症状变化以外的效果的数据有限。(PsycInfo Database Record (c) 2024 APA, 版权所有)。
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引用次数: 0
Examining strength at home couples to prevent intimate partner violence on a military installation: A randomized controlled trial. 研究家庭中夫妻的力量,预防军事设施中的亲密伴侣暴力:随机对照试验。
IF 5.9 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-04-01 Epub Date: 2024-01-11 DOI: 10.1037/ccp0000863
Casey T Taft, Emily F Rothman, Matthew W Gallagher, Evelyn G Hamilton, Anissa Garza, Suzannah K Creech

Objectives: In this study, the effectiveness of a couples-based group intervention to prevent intimate partner violence (IPV), Strength at Home Couples (SAH-C), was examined on a military installation relative to a comparison intervention, Supportive Prevention (SP). It was expected that greater reductions in use of physical, psychological, and sexual IPV behaviors, as well as reduced suicidality, would be found among service members and their partners in SAH-C relative to SP.

Method: Participants included 138 couples randomized to SAH-C and SP through a clinical controlled trial embedded in a hybrid effectiveness implementation study which took place on a military installation. The Revised Conflict Tactics Scales and Multidimensional Measure of Emotional Abuse were used to measure IPV, and 13 Military Suicide Research Consortium common data elements were used to assess suicidality.

Results: Service members randomized to SAH-C evidenced greater reductions based on effect sizes across the assessment time points for all IPV variables, including use of overall physical IPV, severe physical IPV, sexual IPV, psychological IPV, and coercive control IPV relative to those randomized to SP. Partners of service members demonstrated a similar general pattern for reductions in use of IPV, but findings were not as robust as for service members. Both service members and partners demonstrated greater reductions in suicidality based on effect sizes when randomized to SAH-C relative to SP.

Conclusions: Findings extend prior work demonstrating the promising effects of SAH-C delivered in the military context and highlight the possible benefits of SAH-C in preventing self-harm thoughts and behaviors. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

研究目的在这项研究中,我们在一个军事设施中考察了以夫妻为基础的预防亲密伴侣暴力(IPV)的团体干预措施--"家庭中的夫妻力量"(SAH-C)与对比干预措施--"支持性预防"(SP)的效果。预计与 SP 相比,参加 SAH-C 的军人及其伴侣在使用身体、心理和性 IPV 行为方面会有更大的减少,自杀率也会降低:参与者包括138对夫妇,他们通过一项临床对照试验被随机分配到SAH-C和SP中,该试验嵌入了一项在军事设施中进行的混合有效性实施研究中。修订版冲突策略量表和情感虐待多维测量法用于测量IPV,13个军事自杀研究联盟的通用数据元素用于评估自杀倾向:结果:与随机接受SP治疗的军人相比,随机接受SAH-C治疗的军人在所有IPV变量(包括总体身体IPV、严重身体IPV、性IPV、心理IPV和胁迫性控制IPV的使用)的评估时间点上都有更大的减少(基于效应大小)。服役人员的伴侣在减少使用 IPV 方面表现出了类似的总体模式,但研究结果不如服役人员那样有力。根据效应大小,相对于 SP,随机接受 SAH-C 治疗的服役人员及其伴侣的自杀率都有更大的降低:研究结果扩展了之前的工作,证明了在军队环境中实施SAH-C的良好效果,并强调了SAH-C在预防自残想法和行为方面可能带来的益处。(PsycInfo Database Record (c) 2024 APA,保留所有权利)。
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引用次数: 0
Changes in positive and negative affect in psychotherapy for depression and anxiety. 抑郁症和焦虑症心理治疗中积极和消极情绪的变化。
IF 5.9 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-04-01 Epub Date: 2023-12-21 DOI: 10.1037/ccp0000865
Nora M Barnes-Horowitz, Allison Metts, David Rosenfield, Julia S Yarrington, Michael Treanor, Aileen Echiverri-Cohen, Thomas Ritz, Alicia E Meuret, Michelle G Craske

Objective: Positive and negative affect play critical roles in depression and anxiety treatment, but the dynamic processes of how affect changes over treatment in relation to changes in symptoms is unclear. The study goal was to examine relationships among changes in positive and negative affect with changes in depression and anxiety symptoms.

Method: This secondary analysis used a combined sample (N = 196) of two trials (Craske et al., 2019, 2023) comparing positive affect treatment (PAT) to negative affect treatment. Longitudinal cross-lag panel models explored whether changes in positive and negative affect (Positive and Negative Affect Schedule; Watson et al., 1988) predicted subsequent changes in depression and anxiety symptoms (Depression Anxiety Stress Scales; Lovibond & Lovibond, 1995), whether symptoms predicted subsequent changes in affect, and whether treatment condition moderated these relationships.

Results: Increases in positive affect predicted subsequent decreases in depression and anxiety symptoms, regardless of treatment condition. Symptoms did not reciprocally predict changes in positive affect. For individuals in PAT, decreases in negative affect predicted subsequent decreases in symptoms. Moreover, decreases in symptoms predicted subsequent decreases in negative affect, regardless of treatment condition.

Conclusions: Results did not support a reciprocal relationship between positive affect and symptoms of depression and anxiety since positive affect predicted depression and anxiety symptoms but not vice versa. Results supported a reciprocal relationship between negative affect and symptoms of depression and anxiety since negative affect predicted depression and anxiety symptoms in PAT, and depression and anxiety symptoms predicted negative affect in both treatment conditions. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

目的:积极情绪和消极情绪在抑郁症和焦虑症治疗中起着至关重要的作用,但情绪在治疗过程中的变化与症状变化之间的动态变化过程尚不清楚。本研究旨在探讨积极情绪和消极情绪的变化与抑郁和焦虑症状变化之间的关系:这项二次分析使用了两项试验(Craske 等人,2019 年,2023 年)的合并样本(N = 196),将积极情绪治疗(PAT)与消极情绪治疗进行了比较。纵向跨滞后面板模型探讨了积极情绪和消极情绪的变化(积极情绪和消极情绪量表;Watson等人,1988年)是否能预测抑郁和焦虑症状(抑郁焦虑压力量表;Lovibond和Lovibond,1995年)的后续变化,症状是否能预测情感的后续变化,以及治疗条件是否能调节这些关系:结果:无论治疗条件如何,积极情绪的增加都预示着随后抑郁和焦虑症状的减少。症状并不能相互预测积极情绪的变化。对于 PAT 患者来说,负性情绪的降低预示着随后症状的减轻。此外,无论治疗条件如何,症状的减轻都会预示着消极情绪的减轻:结果不支持积极情绪与抑郁和焦虑症状之间的相互关系,因为积极情绪能预测抑郁和焦虑症状,反之亦然。结果支持负性情绪与抑郁和焦虑症状之间的相互关系,因为负性情绪可以预测 PAT 中的抑郁和焦虑症状,而抑郁和焦虑症状可以预测两种治疗条件下的负性情绪。(PsycInfo Database Record (c) 2023 APA,保留所有权利)。
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引用次数: 0
Predicting effects of a digital stress intervention for patients with depressive symptoms: Development and validation of meta-analytic prognostic models using individual participant data. 预测数字压力干预对抑郁症状患者的影响:利用个体参与者数据开发和验证元分析预后模型。
IF 5.9 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-04-01 Epub Date: 2023-12-21 DOI: 10.1037/ccp0000852
Mathias Harrer, Harald Baumeister, Pim Cuijpers, Elena Heber, Dirk Lehr, Ronald C Kessler, David Daniel Ebert

Objective: Digital stress interventions could be helpful as an "indirect" treatment for depression, but it remains unclear for whom this is a viable option. In this study, we developed models predicting individualized benefits of a digital stress intervention on depressive symptoms at 6-month follow-up.

Method: Data of N = 1,525 patients with depressive symptoms (Center for Epidemiological Studies' Depression Scale, CES-D ≥ 16) from k = 6 randomized trials (digital stress intervention vs. waitlist) were collected. Prognostic models were developed using multilevel least absolute shrinkage and selection operator and boosting algorithms, and were validated using bootstrap bias correction and internal-external cross-validation. Subsequently, expected effects among those with and without a treatment recommendation were estimated based on clinically derived treatment assignment cut points.

Results: Performances ranged from R² = 21.0%-23.4%, decreasing only slightly after model optimism correction (R² = 17.0%-19.6%). Predictions were greatly improved by including an interim assessment of depressive symptoms (optimism-corrected R2 = 32.6%-35.6%). Using a minimally important difference of d = -0.24 as assignment cut point, approximately 84.6%-93.3% of patients are helped by this type of intervention, while the remaining 6.7%-15.4% would experience clinically negligible benefits (δ^ = -0.02 to -0.19). Using reliable change as cut point, a smaller subset (39.3%-46.2%) with substantial expected benefits (δ^ = -0.68) receives a treatment recommendation.

Conclusions: Meta-analytic prognostic models applied to individual participant data can be used to predict differential benefits of a digital stress intervention as an indirect treatment for depression. While most patients seem to benefit, the developed models could be helpful as a screening tool to identify those for whom a more intensive depression treatment is needed. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

目的:数字压力干预作为一种 "间接 "治疗抑郁症的方法可能会有所帮助,但对于哪些人来说这是一种可行的选择仍不清楚。在这项研究中,我们建立了一些模型,预测数字压力干预在 6 个月随访时对抑郁症状的个体化益处:方法:从 k = 6 项随机试验(数字压力干预与等待名单)中收集了 N = 1,525 名抑郁症状患者(流行病学研究中心抑郁量表,CES-D ≥ 16)的数据。使用多层次最小绝对收缩和选择算子以及提升算法建立了预后模型,并使用引导偏差校正和内部外部交叉验证进行了验证。随后,根据临床得出的治疗分配切点,估算了有治疗建议和无治疗建议人群的预期效果:结果:结果表明,R²=21.0%-23.4%,在模型乐观度校正后(R²=17.0%-19.6%),结果表明模型乐观度略有下降。通过对抑郁症状进行中期评估,预测结果大大提高(乐观校正后的 R2 = 32.6%-35.6%)。以最小重要差异 d = -0.24 作为分配切点,约有 84.6%-93.3% 的患者可通过此类干预获得帮助,而其余 6.7%-15.4% 的患者的临床获益可忽略不计(δ^ = -0.02 至 -0.19)。以可靠的变化作为切点,较小的子集(39.3%-46.2%)具有可观的预期收益(δ^ = -0.68),可获得治疗建议:结论:应用于个体参与者数据的元分析预后模型可用于预测数字压力干预作为抑郁症间接治疗方法的不同益处。虽然大多数患者似乎都能从中获益,但所开发的模型可以作为一种筛选工具,帮助确定哪些患者需要接受更深入的抑郁症治疗。(PsycInfo Database Record (c) 2023 APA, 版权所有)。
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引用次数: 0
A controlled trial of adaptive disclosure-enhanced to improve functioning and treat posttraumatic stress disorder. 为改善功能和治疗创伤后应激障碍而进行的适应性披露强化对照试验。
IF 4.5 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-03-01 DOI: 10.1037/ccp0000873
Brett T Litz, Julie Yeterian, Danielle Berke, Ariel J Lang, Matt J Gray, Tasha Nienow, Sheila Frankfurt, Jeanette Irene Harris, Shira Maguen, Luke Rusowicz-Orazem

Objective: This is a randomized controlled trial (NCT03056157) of an enhanced adaptive disclosure (AD) psychotherapy compared to present-centered therapy (PCT; each 12 sessions) in 174 veterans with posttraumatic stress disorder (PTSD) related to traumatic loss (TL) and moral injury (MI). AD employs different strategies for different trauma types. AD-Enhanced (AD-E) uses letter writing (e.g., to the deceased), loving-kindness meditation, and bolstered homework to facilitate improved functioning to repair TL and MI-related trauma.

Method: The primary outcomes were the Sheehan Disability Scale (SDS), evaluated at baseline, throughout treatment, and at 3- and 6-month follow-ups (Brief Inventory of Psychosocial Functioning was also administered), the Clinician-Administered PTSD Scale (CAPS-5), the Dimensions of Anger Reactions, the Revised Conflict Tactics Scale, and the Quick Drinking Screen.

Results: There were statistically significant between-group differences on two outcomes: The intent-to-treat (ITT) mixed-model analysis of SDS scores indicated greater improvement from baseline to posttreatment in the AD-E group (d = 2.97) compared to the PCT group, d = 1.86; -2.36, 95% CI [-3.92, -0.77], t(1,510) = -2.92, p < .001, d = 0.15. Twenty-one percent more AD-E cases made clinically significant changes on the SDS than PCT cases. From baseline to posttreatment, AD-E was also more efficacious on the CAPS-5 (d = 0.39). These differential effects did not persist at follow-up intervals.

Conclusion: This was the first psychotherapy of veterans with TL/MI-related PTSD to show superiority relative to PCT with respect to functioning and PTSD, although the differential effect sizes were small to medium and not maintained at follow-up. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

目的:这是一项随机对照试验(NCT03056157):这是一项随机对照试验(NCT03056157),研究对象是174名患有创伤后应激障碍(PTSD)的退伍军人,他们都患有与创伤性失落(TL)和精神伤害(MI)相关的PTSD。针对不同的创伤类型,AD 采用了不同的策略。AD增强型(AD-E)采用写信(如给逝者)、慈爱冥想和强化家庭作业等方法,促进功能改善,以修复TL和MI相关创伤:主要结果包括基线、整个治疗过程、3 个月和 6 个月随访时评估的希恩残疾量表(SDS)(同时还进行了社会心理功能简表的评估)、临床医师管理创伤后应激障碍量表(CAPS-5)、愤怒反应维度、修订版冲突策略量表和快速饮酒筛查:在两项结果上,组间差异具有统计学意义:SDS评分的意向治疗(ITT)混合模型分析表明,与PCT组(d = 1.86; -2.36, 95% CI [-3.92, -0.77],t(1,510) = -2.92, p < .001,d = 0.15)相比,AD-E组从基线到治疗后的改善幅度更大(d = 2.97)。在SDS上有显著临床变化的AD-E病例比PCT病例多21%。从基线到治疗后,AD-E 对 CAPS-5 的疗效也更好(d = 0.39)。结论:这是首次对退伍军人进行心理治疗:这是对患有 TL/MI 相关创伤后应激障碍的退伍军人进行的首次心理治疗,在功能和创伤后应激障碍方面显示出相对于 PCT 的优越性,尽管差异效应大小为小到中等,且在随访中并未保持。(PsycInfo Database Record (c) 2024 APA,保留所有权利)。
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引用次数: 0
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Journal of consulting and clinical psychology
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