Pub Date : 2020-01-01DOI: 10.35248/2155-9554.20.11.539
Si-Ying Sun, Xiang Nong
Aspergillosis refers to chronic inflammatory changes such as skin, nails, external auditory meatus, sinuses, orbits, bronchial tubes, lungs and meninges caused by some pathogenic Aspergillus. Aspergillosis is an infection caused by a type of mold (fungus). The illnesses resulting from aspergillosis infection usually affect the respiratory system, but their signs and severity vary greatly. It is a common conditioned pathogen fungus, in which Aspergillus fumigatus, Aspergillus flavus, Aspergillus terreus, Aspergillus niger and Aspergillus nodulans can cause disease under certain conditions. We reported a case of irritation contact dermatitis which led to fungal infection, confirmed by repeatedly fungal microscopy and fungal culture. We found unreasonable use of topical drugs that not only caused irritation contact dermatitis, but also led to fungal infection through damage skin barrier.
{"title":"Irritation Contact Dermatitis Lead to Fungal Infection: Report of One Case","authors":"Si-Ying Sun, Xiang Nong","doi":"10.35248/2155-9554.20.11.539","DOIUrl":"https://doi.org/10.35248/2155-9554.20.11.539","url":null,"abstract":"Aspergillosis refers to chronic inflammatory changes such as skin, nails, external auditory meatus, sinuses, orbits, bronchial tubes, lungs and meninges caused by some pathogenic Aspergillus. Aspergillosis is an infection caused by a type of mold (fungus). The illnesses resulting from aspergillosis infection usually affect the respiratory system, but their signs and severity vary greatly. It is a common conditioned pathogen fungus, in which Aspergillus fumigatus, Aspergillus flavus, Aspergillus terreus, Aspergillus niger and Aspergillus nodulans can cause disease under certain conditions. We reported a case of irritation contact dermatitis which led to fungal infection, confirmed by repeatedly fungal microscopy and fungal culture. We found unreasonable use of topical drugs that not only caused irritation contact dermatitis, but also led to fungal infection through damage skin barrier.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"1 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76124869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2155-9554.20.11.541
I. Almasry, H. Sabah, V. Lazarević, Abeer Abadallah-Albathali, Nadia Alnaki, A. Alsumait, A. Fikri, A. Alafi
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome, also referred to as drug-induced hypersensitivity syndrome, is a distinct, potentially life-threatening adverse reaction. There are 3 sets of criteria that are helping in diagnosis. We present three challenging cases with DRESS syndrome, and discuss the intravenous immunoglobulins in the therapy. IVIG should be given together with corticosteroids. Multidisciplinary approach is the best way in managing patients with DRESS syndrome.
{"title":"Successful Management of Some Challenging Cases of DRESS Syndrome with Intravenous Immunoglobulins, Case-Based Review Article","authors":"I. Almasry, H. Sabah, V. Lazarević, Abeer Abadallah-Albathali, Nadia Alnaki, A. Alsumait, A. Fikri, A. Alafi","doi":"10.35248/2155-9554.20.11.541","DOIUrl":"https://doi.org/10.35248/2155-9554.20.11.541","url":null,"abstract":"Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome, also referred to as drug-induced hypersensitivity syndrome, is a distinct, potentially life-threatening adverse reaction. There are 3 sets of criteria that are helping in diagnosis. We present three challenging cases with DRESS syndrome, and discuss the intravenous immunoglobulins in the therapy. IVIG should be given together with corticosteroids. Multidisciplinary approach is the best way in managing patients with DRESS syndrome.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"51 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73690477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2155-9554.20.11.542
Palak Garg, M. Ch, Ra, G. Rajauria
Introduction: Diabetes Mellitus (DM) is known to be a chronic multisystem disorder. Since the cutaneous manifestation can be the presenting sign of diabetes mellitus. These are well known and considered common. This work is an attempt to analyze the pattern of various cutaneous manifestations seen in DM in the present lifestyle scenario. In view of increasing prevalence of diabetes mellitus a study of cutaneous manifestation cannot be over emphasized. Aim: To analyze and study the pattern of cutaneous manifestations in diabetic patients. Material and methods: An observational single centered study of 18 months was conducted in department of Dermatology and Medicine at tertiary care teaching hospital. Results: A total of 100 (males were constituted 55% and females were constituted 45%) diagnosed patients of Diabetes Mellitus and were examined. Cutaneous infections were the most common(71%) such as skin tags (33%), cherry angioma (21%), xerosis of skin (19%), acanthosis nigricans (18%), generalized pruritus (12%), xanthelasma palpebraum (8%), diabetic dermopathy (7%), yellow discolouration of hand (5%), diabetic thick skin (2%), rubeosis faciei (2%), and granuloma annulare (1%). Conclusion: It is important to educate patient for proper self-examination, diet control, exercise, change in lifestyle, regular treatment along with monitoring of blood sugar (HbA1c) at regular intervals to detect infections and other manifestations of DM.
{"title":"Evaluation of Cutaneous Manifestation of Diabetes Mellitus","authors":"Palak Garg, M. Ch, Ra, G. Rajauria","doi":"10.35248/2155-9554.20.11.542","DOIUrl":"https://doi.org/10.35248/2155-9554.20.11.542","url":null,"abstract":"Introduction: Diabetes Mellitus (DM) is known to be a chronic multisystem disorder. Since the cutaneous manifestation can be the presenting sign of diabetes mellitus. These are well known and considered common. This work is an attempt to analyze the pattern of various cutaneous manifestations seen in DM in the present lifestyle scenario. In view of increasing prevalence of diabetes mellitus a study of cutaneous manifestation cannot be over emphasized. Aim: To analyze and study the pattern of cutaneous manifestations in diabetic patients. Material and methods: An observational single centered study of 18 months was conducted in department of Dermatology and Medicine at tertiary care teaching hospital. Results: A total of 100 (males were constituted 55% and females were constituted 45%) diagnosed patients of Diabetes Mellitus and were examined. Cutaneous infections were the most common(71%) such as skin tags (33%), cherry angioma (21%), xerosis of skin (19%), acanthosis nigricans (18%), generalized pruritus (12%), xanthelasma palpebraum (8%), diabetic dermopathy (7%), yellow discolouration of hand (5%), diabetic thick skin (2%), rubeosis faciei (2%), and granuloma annulare (1%). Conclusion: It is important to educate patient for proper self-examination, diet control, exercise, change in lifestyle, regular treatment along with monitoring of blood sugar (HbA1c) at regular intervals to detect infections and other manifestations of DM.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"10 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80938060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2155-9554.20.11.E108
D. Rubenstein
Rosacea is a chronic and relapsing inflammatory skin disorder that primarily involves the central face. Common clinical features include facial erythema, telangiectasias, and inflammatory papules or pustules. Many patients seek therapy due to concern over the effect of rosacea on physical appearance. As there is no cure for rosacea, treatment is focused on symptom suppression. Rosacea can manifest with a wide variety of cutaneous features. Examples include persistent centrofacial redness, phymatous skin changes (eg, rhinophyma), papules, pustules, flushing, telangiectases, burning or stinging sensations, edema, and skin dryness.
{"title":"Rosacea: An Overview from the point of Dermatologist","authors":"D. Rubenstein","doi":"10.35248/2155-9554.20.11.E108","DOIUrl":"https://doi.org/10.35248/2155-9554.20.11.E108","url":null,"abstract":"Rosacea is a chronic and relapsing inflammatory skin disorder that primarily involves the central face. Common clinical features include facial erythema, telangiectasias, and inflammatory papules or pustules. Many patients seek therapy due to concern over the effect of rosacea on physical appearance. As there is no cure for rosacea, treatment is focused on symptom suppression. Rosacea can manifest with a wide variety of cutaneous features. Examples include persistent centrofacial redness, phymatous skin changes (eg, rhinophyma), papules, pustules, flushing, telangiectases, burning or stinging sensations, edema, and skin dryness.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"118 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77610405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2155-9554.20.11.521
M. Fernández-Guarino, S. AboínGonzález, Á. González-Cantero, C. Arsuaga, P. Lázaro
Introduction: Large prospective studies evaluating efficacy of narrow band ultraviolet B (NB-UVB) in psoriasis in terms of PASI75 and PASI90 are scarce in the literature. Material and methods: A prospective, open and observational study was conducted. Patients treated with narrow band ultraviolet B (NB-UVB) for psoriasis was included. Treatment target was a reduction of 90% from basal PASI (PASI90), but if patients did not achieve this response after 20 sessions, treatment was continued until PASI75 clearance was achieved. Patients were followed up and relapses were retreated with the same PASI at the first time. Relation between PASI before treatment and total doses needed to achieve PASI75 or PASI90 was studied. Results: Among the 242 patients that received NB-UVB for psoriasis, 102 had guttate psoriasis (GP) and 122 had plaque psoriasis (PP). PASI90 was achieved in 89.1% of patients with GP and 64,8% of patients with PP. Response was significantly better (p<0.05) in GP patients. Retreated patients affected of PP needed the same doses as the first treatment received (p>0.005). Patients with higher PASI need more doses to clear up. Conclusion: Phototherapy with NB-UVB is significantly more effective in patients with GP than patients with PP. Patients retreated seems to need the same doses. Initial PASI can predict the total doses needed to achieve PASI75 or PASI90.
{"title":"Phototherapy with Narrow-Band Ultraviolet B in Adult Psoriasis: A Study in Clinical Practice","authors":"M. Fernández-Guarino, S. AboínGonzález, Á. González-Cantero, C. Arsuaga, P. Lázaro","doi":"10.35248/2155-9554.20.11.521","DOIUrl":"https://doi.org/10.35248/2155-9554.20.11.521","url":null,"abstract":"Introduction: Large prospective studies evaluating efficacy of narrow band ultraviolet B (NB-UVB) in psoriasis in terms of PASI75 and PASI90 are scarce in the literature. Material and methods: A prospective, open and observational study was conducted. Patients treated with narrow band ultraviolet B (NB-UVB) for psoriasis was included. Treatment target was a reduction of 90% from basal PASI (PASI90), but if patients did not achieve this response after 20 sessions, treatment was continued until PASI75 clearance was achieved. Patients were followed up and relapses were retreated with the same PASI at the first time. Relation between PASI before treatment and total doses needed to achieve PASI75 or PASI90 was studied. Results: Among the 242 patients that received NB-UVB for psoriasis, 102 had guttate psoriasis (GP) and 122 had plaque psoriasis (PP). PASI90 was achieved in 89.1% of patients with GP and 64,8% of patients with PP. Response was significantly better (p<0.05) in GP patients. Retreated patients affected of PP needed the same doses as the first treatment received (p>0.005). Patients with higher PASI need more doses to clear up. Conclusion: Phototherapy with NB-UVB is significantly more effective in patients with GP than patients with PP. Patients retreated seems to need the same doses. Initial PASI can predict the total doses needed to achieve PASI75 or PASI90.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"399 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89747994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2155-9554.20.11.528
S. Belmourida, S. Sialiti, M. Meziane, N. Ismaili, L. Benzekri, B. Hassam, K. Senouci
Hobnail Hemangioma is a rare entity, first described by Santa cruz and Aronberg in 1988, it’s a lesion of vascular origin, probably lymphatic. The most common clinical feature is a solitary violaceous papule surrounded by a pale, thin area and a peripheral ecchymotic ring, simulating a target. We report a rare case of hobnail hemangioma.
{"title":"The Hobnail Hemangioma","authors":"S. Belmourida, S. Sialiti, M. Meziane, N. Ismaili, L. Benzekri, B. Hassam, K. Senouci","doi":"10.35248/2155-9554.20.11.528","DOIUrl":"https://doi.org/10.35248/2155-9554.20.11.528","url":null,"abstract":"Hobnail Hemangioma is a rare entity, first described by Santa cruz and Aronberg in 1988, it’s a lesion of vascular origin, probably lymphatic. The most common clinical feature is a solitary violaceous papule surrounded by a pale, thin area and a peripheral ecchymotic ring, simulating a target. We report a rare case of hobnail hemangioma.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"33 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84267813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2155-9554.20.11.523
M. Saliani
Background: Increased standardization may be necessary to maximize benefits and minimize complications with fullface rejuvenation using hyaluronic acid (HA) fillers. The aim of this study was to assess the utility and safety of the standardized MD Codes approach. Methods: This was a retrospective review of data from 84 patients receiving full-face rejuvenation with HA fillers using the MD Codes technique within a single treatment plan, across two visits separated by ~1 month. Results: Participants had a mean age of 49.1 ± 9.9 years, and 83 (98.8%) were female. They were treated with 527 syringes of filler (6.3 ± 1.8 per patient): 334 syringes (63.4%; 4.0 ± 1.5 per patient) during visit 1 and 193 (36.6%; 2.3 ± 1.1 per patient) during visit 2. The most commonly treated areas were the cheek (n=84; 100%) and nasolabial fold (n=26; 31.0%) at visit 1, and the nasolabial fold (n=36; 43.9%) and tear trough (n=35; 42.7%) at visit 2. Eight adverse events were recorded in 6 patients (7.1%): bruising, n=4; pain, n=4. All were minor and transient. There were no lateonset complications. Conclusion: Full-face rejuvenation using the MD Codes technique can be successfully performed with minimal complications. This approach may define a new standard of care.
{"title":"Full-Face Rejuvenation with Hyaluronic Acid Fillers based on the MD Codes Technique: A Retrospective, Single-Center Study","authors":"M. Saliani","doi":"10.35248/2155-9554.20.11.523","DOIUrl":"https://doi.org/10.35248/2155-9554.20.11.523","url":null,"abstract":"Background: Increased standardization may be necessary to maximize benefits and minimize complications with fullface rejuvenation using hyaluronic acid (HA) fillers. The aim of this study was to assess the utility and safety of the standardized MD Codes approach. Methods: This was a retrospective review of data from 84 patients receiving full-face rejuvenation with HA fillers using the MD Codes technique within a single treatment plan, across two visits separated by ~1 month. Results: Participants had a mean age of 49.1 ± 9.9 years, and 83 (98.8%) were female. They were treated with 527 syringes of filler (6.3 ± 1.8 per patient): 334 syringes (63.4%; 4.0 ± 1.5 per patient) during visit 1 and 193 (36.6%; 2.3 ± 1.1 per patient) during visit 2. The most commonly treated areas were the cheek (n=84; 100%) and nasolabial fold (n=26; 31.0%) at visit 1, and the nasolabial fold (n=36; 43.9%) and tear trough (n=35; 42.7%) at visit 2. Eight adverse events were recorded in 6 patients (7.1%): bruising, n=4; pain, n=4. All were minor and transient. There were no lateonset complications. Conclusion: Full-face rejuvenation using the MD Codes technique can be successfully performed with minimal complications. This approach may define a new standard of care.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"262 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77014905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/21559554.20.11.E107
M. El-Domyati
As we are aware of this pandemic outbreak of COVID-19, the people across the globe has to be aware that it is been caused by SARS-CoV-2 coronavirus. SARS-CoV-2 is highly contagious and often leads to severe viral pneumonia with respiratory failure and death in the elderly and subjects with pre-existing conditions. The fatal rate for COVID-19 is growing exponentially in many countries like Italy, Spain, South Korea, China, USA with the doubling time.
{"title":"Current Pandemic Situation around the World (COVID-19)","authors":"M. El-Domyati","doi":"10.35248/21559554.20.11.E107","DOIUrl":"https://doi.org/10.35248/21559554.20.11.E107","url":null,"abstract":"As we are aware of this pandemic outbreak of COVID-19, the people across the globe has to be aware that it is been caused by SARS-CoV-2 coronavirus. SARS-CoV-2 is highly contagious and often leads to severe viral pneumonia with respiratory failure and death in the elderly and subjects with pre-existing conditions. The fatal rate for COVID-19 is growing exponentially in many countries like Italy, Spain, South Korea, China, USA with the doubling time.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"11 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82139006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Due to the increasing prevalence of so called "life style diseases", such as diabetes, obesity or hypertension, the number of associated vascular and nerve lesions increases. In the lower limbs in particular, bagatelle trauma causes wounds that lead to wound healing disorders and chronic wounds
{"title":"A Naevus Sebaceous with Tumour of the Follicular Infundibulum, Trichilemmoma, Desmoplastic Trichilemmoma, Apocrine Adenoma and Syringocystadenoma Papilliferum: Report of a Case","authors":"Coyne Jd","doi":"10.31579/2578-8949/046","DOIUrl":"https://doi.org/10.31579/2578-8949/046","url":null,"abstract":"Due to the increasing prevalence of so called \"life style diseases\", such as diabetes, obesity or hypertension, the number of associated vascular and nerve lesions increases. In the lower limbs in particular, bagatelle trauma causes wounds that lead to wound healing disorders and chronic wounds","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89586454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-08DOI: 10.4172/2155-9554.1000476
B. Julien, Khonayser Pierre, El Haber Costantin, G. Samer, Gh., our Fatima, M�garban� Hala
Keratosis Lichenoides Chronica (KLC) is a rare and chronic disorder of keratinization of unknown etiology. It is a progressive disease characterized by the linear and reticulate appearance of erythematous-to-violaceous keratotic and lichenoid papules over the trunk and limbs. KLC is uncommon in the pediatric population is uncommon and its clinical and histopathological presentation differs from the adult form. We report two cases in pediatric population, one of which has been treated successfully by acitretin. We also review the clinical and histopathologic features of the pediatric versus the adult form.
{"title":"Two Cases of Pediatric Keratosis Lichenoides Chronica with Review of the Clinical and Hitopathological Features of Pediatric versus Adult Presentation and Treatment with Acitretin","authors":"B. Julien, Khonayser Pierre, El Haber Costantin, G. Samer, Gh., our Fatima, M�garban� Hala","doi":"10.4172/2155-9554.1000476","DOIUrl":"https://doi.org/10.4172/2155-9554.1000476","url":null,"abstract":"Keratosis Lichenoides Chronica (KLC) is a rare and chronic disorder of keratinization of unknown etiology. It is a progressive disease characterized by the linear and reticulate appearance of erythematous-to-violaceous keratotic and lichenoid papules over the trunk and limbs. KLC is uncommon in the pediatric population is uncommon and its clinical and histopathological presentation differs from the adult form. We report two cases in pediatric population, one of which has been treated successfully by acitretin. We also review the clinical and histopathologic features of the pediatric versus the adult form.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"14 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2019-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89303149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}