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Idiopathic Pyoderma Gangrenosum in a Toddler: Case Report 幼儿特发性坏疽性脓皮病1例报告
Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.516
Waleed Alajroush, Nouf Alqahtani, A. Alfaleh
Pyoderma Gangrenosum (PG) is an inflammatory neutrophilic dermatosis of unknown etiology, primarily sterile with no underlying infectious process and commonly present as an association with a systemic disease. It is rarely seen in pediatric age group and here we describe an atypical presentation of painless cutaneous ulcerative eruption involving the upper thighs and buttock in an otherwise healthy 14-month-old girl. Diagnosis of idiopathic PG was made based on clinical and histopathological correlation, and after excluding other etiologies including immunodeficiency and infections. The patient improved and responded well within 4 weeks of treatment with systemic corticosteroids.
坏疽性脓皮病(Pyoderma Gangrenosum, PG)是一种病因不明的炎症性中性粒细胞皮肤病,主要是无菌的,没有潜在的感染过程,通常与全身性疾病有关。这是罕见的儿科年龄组,在这里我们描述了一个非典型的无痛皮肤溃疡性爆发涉及大腿上部和臀部在其他方面健康的14个月大的女孩。特发性PG的诊断是基于临床和组织病理学相关性,并在排除其他病因包括免疫缺陷和感染后做出的。患者在全身性糖皮质激素治疗4周后病情改善,反应良好。
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引用次数: 0
Evaluation of Cutaneous Manifestation of Diabetes Mellitus 糖尿病皮肤表现的评价
Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.542
Palak Garg, M. Ch, Ra, G. Rajauria
Introduction: Diabetes Mellitus (DM) is known to be a chronic multisystem disorder. Since the cutaneous manifestation can be the presenting sign of diabetes mellitus. These are well known and considered common. This work is an attempt to analyze the pattern of various cutaneous manifestations seen in DM in the present lifestyle scenario. In view of increasing prevalence of diabetes mellitus a study of cutaneous manifestation cannot be over emphasized. Aim: To analyze and study the pattern of cutaneous manifestations in diabetic patients. Material and methods: An observational single centered study of 18 months was conducted in department of Dermatology and Medicine at tertiary care teaching hospital. Results: A total of 100 (males were constituted 55% and females were constituted 45%) diagnosed patients of Diabetes Mellitus and were examined. Cutaneous infections were the most common(71%) such as skin tags (33%), cherry angioma (21%), xerosis of skin (19%), acanthosis nigricans (18%), generalized pruritus (12%), xanthelasma palpebraum (8%), diabetic dermopathy (7%), yellow discolouration of hand (5%), diabetic thick skin (2%), rubeosis faciei (2%), and granuloma annulare (1%). Conclusion: It is important to educate patient for proper self-examination, diet control, exercise, change in lifestyle, regular treatment along with monitoring of blood sugar (HbA1c) at regular intervals to detect infections and other manifestations of DM.
简介:糖尿病(DM)是一种慢性多系统疾病。因为皮肤表现可能是糖尿病的表现。这些都是众所周知的,被认为是常见的。这项工作是试图分析在当前生活方式的情况下,糖尿病的各种皮肤表现的模式。鉴于糖尿病的发病率越来越高,对其皮肤表现的研究再强调也不为过。目的:分析和研究糖尿病患者的皮肤表现模式。材料与方法:在三级护理教学医院皮肤内科进行为期18个月的单中心观察性研究。结果:共对100例确诊糖尿病患者(男性占55%,女性占45%)进行检查。皮肤感染是最常见的(71%),如皮赘(33%)、樱桃血管瘤(21%)、皮肤干燥(19%)、黑皮棘病(18%)、全身瘙痒(12%)、棕榈黄斑(8%)、糖尿病性皮肤病(7%)、手部黄色变(5%)、糖尿病性厚皮(2%)、面部红斑病(2%)和环形肉芽肿(1%)。结论:教育患者做好自我检查、控制饮食、运动、改变生活方式、定期治疗,定期监测血糖(HbA1c),及时发现感染及其他DM表现。
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引用次数: 0
Xeroderma Pigmentosum with Acute Myeloid Leukemia and Meningiomas: Review of Literature 色素性干皮病合并急性髓性白血病和脑膜瘤:文献回顾
Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.524
N. Mian, P. Kushwaha
Xeroderma Pigmentosum (XP) a unique disorder, inherited as an autosomal recessive genodermatosis. Characterized by photosensitivity, freckly pigmented changes, premature skin ageing, telegiectasis, warty and papillomatous growth and malignant tumor development in later stage. Results from mutation in seven nucleotide excision repair gene (XPA to XP-G complement groups) and post replication repair defect (XP-Variant). This report aims to acknowledge the unique combination of XP along with neurological defects in a patient of acute myeloid leukemia.
着色性干皮病(XP)是一种独特的疾病,遗传为常染色体隐性遗传性皮肤病。特征为光敏、雀斑色素改变、皮肤过早老化、远端扩张、疣状和乳头状瘤生长,后期发展为恶性肿瘤。结果:7个核苷酸切除修复基因(XPA到XP-G补体群)突变和复制后修复缺陷(XP-Variant)。本报告的目的是承认XP的独特组合以及神经缺陷的急性髓性白血病患者。
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引用次数: 0
Rosacea: An Overview from the point of Dermatologist 酒渣鼻:从皮肤科医生的角度概述
Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.E108
D. Rubenstein
Rosacea is a chronic and relapsing inflammatory skin disorder that primarily involves the central face. Common clinical features include facial erythema, telangiectasias, and inflammatory papules or pustules. Many patients seek therapy due to concern over the effect of rosacea on physical appearance. As there is no cure for rosacea, treatment is focused on symptom suppression. Rosacea can manifest with a wide variety of cutaneous features. Examples include persistent centrofacial redness, phymatous skin changes (eg, rhinophyma), papules, pustules, flushing, telangiectases, burning or stinging sensations, edema, and skin dryness.
酒渣鼻是一种慢性复发性炎症性皮肤病,主要累及面部中部。常见的临床特征包括面部红斑、毛细血管扩张、炎症性丘疹或脓疱。许多患者由于担心酒渣鼻对身体外观的影响而寻求治疗。由于酒渣鼻无法治愈,治疗的重点是抑制症状。酒渣鼻可表现为各种各样的皮肤特征。例如持续的面部中心区发红、皮肤肿变(如鼻赘)、丘疹、脓疱、潮红、毛细血管扩张、灼烧或刺痛感、水肿和皮肤干燥。
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引用次数: 0
The Hobnail Hemangioma 鞋钉血管瘤
Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.528
S. Belmourida, S. Sialiti, M. Meziane, N. Ismaili, L. Benzekri, B. Hassam, K. Senouci
Hobnail Hemangioma is a rare entity, first described by Santa cruz and Aronberg in 1988, it’s a lesion of vascular origin, probably lymphatic. The most common clinical feature is a solitary violaceous papule surrounded by a pale, thin area and a peripheral ecchymotic ring, simulating a target. We report a rare case of hobnail hemangioma.
鞋钉血管瘤是一种罕见的血管瘤,于1988年由Santa cruz和Aronberg首次描述,它是一种起源于血管的病变,可能是淋巴管。最常见的临床特征是孤立的紫色丘疹,周围有苍白,薄的区域和周围的瘀斑环,模拟靶。我们报告一例罕见的鞋钉血管瘤。
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引用次数: 0
Phototherapy with Narrow-Band Ultraviolet B in Adult Psoriasis: A Study in Clinical Practice 窄带紫外线B光疗治疗成人银屑病的临床研究
Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.521
M. Fernández-Guarino, S. AboínGonzález, Á. González-Cantero, C. Arsuaga, P. Lázaro
Introduction: Large prospective studies evaluating efficacy of narrow band ultraviolet B (NB-UVB) in psoriasis in terms of PASI75 and PASI90 are scarce in the literature. Material and methods: A prospective, open and observational study was conducted. Patients treated with narrow band ultraviolet B (NB-UVB) for psoriasis was included. Treatment target was a reduction of 90% from basal PASI (PASI90), but if patients did not achieve this response after 20 sessions, treatment was continued until PASI75 clearance was achieved. Patients were followed up and relapses were retreated with the same PASI at the first time. Relation between PASI before treatment and total doses needed to achieve PASI75 or PASI90 was studied. Results: Among the 242 patients that received NB-UVB for psoriasis, 102 had guttate psoriasis (GP) and 122 had plaque psoriasis (PP). PASI90 was achieved in 89.1% of patients with GP and 64,8% of patients with PP. Response was significantly better (p<0.05) in GP patients. Retreated patients affected of PP needed the same doses as the first treatment received (p>0.005). Patients with higher PASI need more doses to clear up. Conclusion: Phototherapy with NB-UVB is significantly more effective in patients with GP than patients with PP. Patients retreated seems to need the same doses. Initial PASI can predict the total doses needed to achieve PASI75 or PASI90.
文献中很少有以PASI75和PASI90评价窄带紫外线B (NB-UVB)治疗银屑病疗效的大型前瞻性研究。材料与方法:采用前瞻性、开放性、观察性研究。采用窄带紫外线B (NB-UVB)治疗银屑病患者。治疗目标是将基础PASI (PASI90)降低90%,但如果患者在20个疗程后仍未达到这一反应,则继续治疗直到PASI75清除。对患者进行随访,复发患者第一次采用相同的PASI治疗。研究治疗前PASI与达到PASI75或PASI90所需的总剂量之间的关系。结果:在242例接受NB-UVB治疗的银屑病患者中,102例为点滴状银屑病(GP), 122例为斑块状银屑病(PP)。89.1%的GP患者和64.8%的PP患者达到了PASI90,疗效明显更好(p0.005)。PASI较高的患者需要更多的剂量来清除。结论:NB-UVB光疗治疗GP患者的效果明显优于PP患者,治疗后患者似乎需要相同的剂量。初始PASI可以预测达到PASI75或PASI90所需的总剂量。
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引用次数: 1
Full-Face Rejuvenation with Hyaluronic Acid Fillers based on the MD Codes Technique: A Retrospective, Single-Center Study 基于MD编码技术的透明质酸填充剂全脸嫩肤:一项回顾性单中心研究
Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.523
M. Saliani
Background: Increased standardization may be necessary to maximize benefits and minimize complications with fullface rejuvenation using hyaluronic acid (HA) fillers. The aim of this study was to assess the utility and safety of the standardized MD Codes approach. Methods: This was a retrospective review of data from 84 patients receiving full-face rejuvenation with HA fillers using the MD Codes technique within a single treatment plan, across two visits separated by ~1 month. Results: Participants had a mean age of 49.1 ± 9.9 years, and 83 (98.8%) were female. They were treated with 527 syringes of filler (6.3 ± 1.8 per patient): 334 syringes (63.4%; 4.0 ± 1.5 per patient) during visit 1 and 193 (36.6%; 2.3 ± 1.1 per patient) during visit 2. The most commonly treated areas were the cheek (n=84; 100%) and nasolabial fold (n=26; 31.0%) at visit 1, and the nasolabial fold (n=36; 43.9%) and tear trough (n=35; 42.7%) at visit 2. Eight adverse events were recorded in 6 patients (7.1%): bruising, n=4; pain, n=4. All were minor and transient. There were no lateonset complications. Conclusion: Full-face rejuvenation using the MD Codes technique can be successfully performed with minimal complications. This approach may define a new standard of care.
背景:使用透明质酸(HA)填充剂进行全面部年轻化可能需要增加标准化,以最大限度地提高益处并减少并发症。本研究的目的是评估标准化MD代码方法的效用和安全性。方法:回顾性分析84例患者的数据,这些患者使用MD Codes技术在单一治疗方案中使用HA填充剂进行全脸年轻化,两次就诊间隔约1个月。结果:参与者平均年龄49.1±9.9岁,女性83例(98.8%)。共使用填充剂527支(6.3±1.8支/例):334支(63.4%);在第1次和第193次就诊时(36.6%;2.3±1.1 /例)。最常治疗的部位是脸颊(n=84;100%)和鼻唇沟(n=26;31.0%),鼻唇沟(n=36;43.9%)和撕裂槽(n=35;42.7%)。6例(7.1%)患者记录了8个不良事件:瘀伤,n=4;疼痛,n = 4。一切都是微不足道的,转瞬即逝的。无迟发性并发症。结论:MD Codes技术可成功完成全脸年轻化,并发症少。这种方法可能定义一种新的护理标准。
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引用次数: 1
Current Pandemic Situation around the World (COVID-19) 当前全球大流行形势(COVID-19)
Pub Date : 2020-01-01 DOI: 10.35248/21559554.20.11.E107
M. El-Domyati
As we are aware of this pandemic outbreak of COVID-19, the people across the globe has to be aware that it is been caused by SARS-CoV-2 coronavirus. SARS-CoV-2 is highly contagious and often leads to severe viral pneumonia with respiratory failure and death in the elderly and subjects with pre-existing conditions. The fatal rate for COVID-19 is growing exponentially in many countries like Italy, Spain, South Korea, China, USA with the doubling time.
在我们意识到COVID-19大流行爆发的同时,全球人民必须意识到它是由SARS-CoV-2冠状病毒引起的。SARS-CoV-2具有高度传染性,在老年人和已有疾病的受试者中经常导致严重的病毒性肺炎,并伴有呼吸衰竭和死亡。在意大利、西班牙、韩国、中国、美国等许多国家,COVID-19的致死率呈指数级增长,时间翻了一番。
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引用次数: 0
A Naevus Sebaceous with Tumour of the Follicular Infundibulum, Trichilemmoma, Desmoplastic Trichilemmoma, Apocrine Adenoma and Syringocystadenoma Papilliferum: Report of a Case 皮脂腺痣合并滤泡腺瘤、毛囊瘤、纤维增生性毛囊瘤、大汗腺瘤及乳头状囊腺瘤1例报告
Pub Date : 2019-08-09 DOI: 10.31579/2578-8949/046
Coyne Jd
Due to the increasing prevalence of so called "life style diseases", such as diabetes, obesity or hypertension, the number of associated vascular and nerve lesions increases. In the lower limbs in particular, bagatelle trauma causes wounds that lead to wound healing disorders and chronic wounds
由于诸如糖尿病、肥胖或高血压等所谓的“生活方式疾病”日益流行,相关血管和神经病变的数量也在增加。特别是在下肢,小创伤造成伤口,导致伤口愈合障碍和慢性伤口
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引用次数: 0
Two Cases of Pediatric Keratosis Lichenoides Chronica with Review of the Clinical and Hitopathological Features of Pediatric versus Adult Presentation and Treatment with Acitretin 小儿慢性地衣样角化病2例:小儿与成人的临床及病理特点及阿维a治疗
Pub Date : 2019-01-08 DOI: 10.4172/2155-9554.1000476
B. Julien, Khonayser Pierre, El Haber Costantin, G. Samer, Gh., our Fatima, M�garban� Hala
Keratosis Lichenoides Chronica (KLC) is a rare and chronic disorder of keratinization of unknown etiology. It is a progressive disease characterized by the linear and reticulate appearance of erythematous-to-violaceous keratotic and lichenoid papules over the trunk and limbs. KLC is uncommon in the pediatric population is uncommon and its clinical and histopathological presentation differs from the adult form. We report two cases in pediatric population, one of which has been treated successfully by acitretin. We also review the clinical and histopathologic features of the pediatric versus the adult form.
慢性类地衣角化病是一种罕见的慢性疾病,病因不明。它是一种进行性疾病,其特征是躯干和四肢呈线状和网状红斑至紫色角化和地衣样丘疹。KLC在儿科人群中并不常见,其临床和组织病理学表现不同于成人形式。我们报告两例儿科病例,其中一例已成功治疗阿维甙。我们也回顾了临床和组织病理学特点的儿科与成人形式。
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引用次数: 0
期刊
Journal of clinical & experimental dermatology research
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