{"title":"Survival in elderly glioblastoma patients: The often overlooked role of radiotherapy and chemotherapy.","authors":"Rizky Andana Pohan, Khairiyah Khadijah, Putri Bunga Aisyah Pohan, Ronal Surya Aditya, Erfan Ramadhani, Rikas Saputra, Ririn Dwi Astuti","doi":"10.1016/j.jocn.2025.111091","DOIUrl":"https://doi.org/10.1016/j.jocn.2025.111091","url":null,"abstract":"","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":" ","pages":"111091"},"PeriodicalIF":1.9,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-28DOI: 10.1016/j.jocn.2025.111075
Narat Srivali , Charat Thongprayoon , Wisit Cheungpasitporn , Andrey Zinchuk , Brian B. Koo
<div><h3>Introduction</h3><div>Obstructive sleep apnea (OSA) is characterized by repetitive episodes of complete or partial upper airway collapse during sleep. Restless legs syndrome (RLS) is a sleep-related movement disorder characterized by an uncomfortable urge to move the legs, especially during inactivity and evenings. Both OSA and RLS are common with significant overlap: RLS is present in up to 36% of those with OSA. Treatment of OSA with continuous positive airway pressure (CPAP) therapy may influence RLS outcomes. We performed a systematic review to evaluate the impact of CPAP therapy on RLS symptoms and RLS medication usage in individuals with both OSA and RLS.</div></div><div><h3>Method</h3><div>A comprehensive literature search was conducted in MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews from inception to December 7, 2024. The outcomes of interest were the improvement in RLS symptom severity, as measured by standardized scales such as the International RLS Study Group RLS Severity Scale (IRLS), and changes in the usage of RLS medications. The review included clinical trials and observational studies. Inclusion criteria were: studies with a control group or comparison period before CPAP usage, adult participants diagnosed with OSA and RLS, measurements of RLS severity using standardized scales such as the IRLS, and reports on medication usage before and after CPAP therapy. Data extraction included study characteristics, participant demographics, exposure and outcome measurements, and adjusted effect estimates. Exclusion criteria included non-primary research articles such as reviews, editorials, commentaries, letters, studies without standardized assessments of RLS symptoms, and non-English articles. The quality of included studies was assessed using the Newcastle-Ottawa Quality Scale (NOS), and the risk of bias was evaluated using the ROBINS-I tool. The systematic review was registered in PROSPERO (ID: CRD42024550240).</div></div><div><h3>Results</h3><div>The search identified 2,046 articles, with 291 undergoing full-text review, and three studies (3 observational, 0 RCTs) meeting the inclusion criteria, which included 479 patients. CPAP therapy was associated with improvements in RLS symptoms and a reduction in medication usage among patients with coexistent RLS and OSA. The magnitude of these effects varied, with some studies reporting significant improvements while others showed probable changes. The variability in results can be attributed to differences in study designs, sample sizes, and adjustments for confounding factors. These factors highlight the need for more rigorous research to evaluate the benefits of CPAP therapy in patients with coexistent RLS and OSA.</div></div><div><h3>Conclusion</h3><div>CPAP therapy appears beneficial for improving RLS symptoms and reducing medication usage in patients with coexistent OSA and RLS. However, further research with stand
{"title":"Impact of continuous positive airway pressure therapy on restless legs syndrome in patients with coexistent obstructive sleep apnea: A qualitative systematic review","authors":"Narat Srivali , Charat Thongprayoon , Wisit Cheungpasitporn , Andrey Zinchuk , Brian B. Koo","doi":"10.1016/j.jocn.2025.111075","DOIUrl":"10.1016/j.jocn.2025.111075","url":null,"abstract":"<div><h3>Introduction</h3><div>Obstructive sleep apnea (OSA) is characterized by repetitive episodes of complete or partial upper airway collapse during sleep. Restless legs syndrome (RLS) is a sleep-related movement disorder characterized by an uncomfortable urge to move the legs, especially during inactivity and evenings. Both OSA and RLS are common with significant overlap: RLS is present in up to 36% of those with OSA. Treatment of OSA with continuous positive airway pressure (CPAP) therapy may influence RLS outcomes. We performed a systematic review to evaluate the impact of CPAP therapy on RLS symptoms and RLS medication usage in individuals with both OSA and RLS.</div></div><div><h3>Method</h3><div>A comprehensive literature search was conducted in MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews from inception to December 7, 2024. The outcomes of interest were the improvement in RLS symptom severity, as measured by standardized scales such as the International RLS Study Group RLS Severity Scale (IRLS), and changes in the usage of RLS medications. The review included clinical trials and observational studies. Inclusion criteria were: studies with a control group or comparison period before CPAP usage, adult participants diagnosed with OSA and RLS, measurements of RLS severity using standardized scales such as the IRLS, and reports on medication usage before and after CPAP therapy. Data extraction included study characteristics, participant demographics, exposure and outcome measurements, and adjusted effect estimates. Exclusion criteria included non-primary research articles such as reviews, editorials, commentaries, letters, studies without standardized assessments of RLS symptoms, and non-English articles. The quality of included studies was assessed using the Newcastle-Ottawa Quality Scale (NOS), and the risk of bias was evaluated using the ROBINS-I tool. The systematic review was registered in PROSPERO (ID: CRD42024550240).</div></div><div><h3>Results</h3><div>The search identified 2,046 articles, with 291 undergoing full-text review, and three studies (3 observational, 0 RCTs) meeting the inclusion criteria, which included 479 patients. CPAP therapy was associated with improvements in RLS symptoms and a reduction in medication usage among patients with coexistent RLS and OSA. The magnitude of these effects varied, with some studies reporting significant improvements while others showed probable changes. The variability in results can be attributed to differences in study designs, sample sizes, and adjustments for confounding factors. These factors highlight the need for more rigorous research to evaluate the benefits of CPAP therapy in patients with coexistent RLS and OSA.</div></div><div><h3>Conclusion</h3><div>CPAP therapy appears beneficial for improving RLS symptoms and reducing medication usage in patients with coexistent OSA and RLS. However, further research with stand","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"133 ","pages":"Article 111075"},"PeriodicalIF":1.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-28DOI: 10.1016/j.jocn.2025.111081
Leonardo Januário Campos Cardoso , Marcio Yuri Ferreira , Rodrigo Twardowski Scherer , Christian Ken Fukunaga , Jhon E. Bocanegra-Becerra , Ahmet Günkan , Christian Ferreira , Jason Ellis , Yafell Serulle , David Langer
Objectives
Ensuring aneurysm exclusion while maintaining vessel patency is crucial during intracranial aneurysm clipping. Although digital subtraction angiography (DSA) is the gold standard for intraoperative vascular imaging, some centers have reported using fluorescein sodium video angiography (FNa-VA). However, a synthesis of these findings is still lacking. We aim to evaluate the safety and efficacy of FNa-VA in identifying aneurysm remnants and vessel stenosis post-clipping.
Methods
PubMed, Embase, Cochrane, and Web of Science databases were searched for studies reporting on FNa-VA for intraoperative aneurysm clipping assessment. We assessed the rate of mis-clippings identified by FNa-VA, false negatives, and procedure-related side effects. A diagnostic assessment analyzed FNa-VA’s sensitivity, specificity, PPV, and NPV. Single proportion analysis with 95% confidence intervals under a random effects model was used, with heterogeneity examined via I2 and leave-one-out analysis.
Results
Eight studies involving 280 patients with 311 aneurysms were included. FNa-VA identified mis-clippings that eluded visual inspection in 11.94 % of cases (95 % CI: 5.83–18.05, I2 = 59 %), with false negatives in 2.15 % (95 % CI: 0–5.13, I2 = 44 %). It has demonstrated a sensitivity of 50 % and a specificity of 93 %, with PPV and NPV of 52 % and 93 %, respectively. Procedure-related side effects were yellow skin and green urine for 2–3 days following the procedure.
Conclusion
FNa-VA may reduce the risk of mis-clipping during aneurysm surgery, however, it is still prone to false negatives and should be considered a complementary tool rather than used alone. Additionally, it appears to have a safe profile with only mild and transitory side effects.
{"title":"Sodium fluorescein video Angiography–Assisted clipping of intracranial Aneurysms: A systematic review and Meta-Analysis","authors":"Leonardo Januário Campos Cardoso , Marcio Yuri Ferreira , Rodrigo Twardowski Scherer , Christian Ken Fukunaga , Jhon E. Bocanegra-Becerra , Ahmet Günkan , Christian Ferreira , Jason Ellis , Yafell Serulle , David Langer","doi":"10.1016/j.jocn.2025.111081","DOIUrl":"10.1016/j.jocn.2025.111081","url":null,"abstract":"<div><h3>Objectives</h3><div>Ensuring aneurysm exclusion while maintaining vessel patency is crucial during intracranial aneurysm clipping. Although digital subtraction angiography (DSA) is the gold standard for intraoperative vascular imaging, some centers have reported using fluorescein sodium video angiography (FNa-VA). However, a synthesis of these findings is still lacking. We aim to evaluate the safety and efficacy of FNa-VA in identifying aneurysm remnants and vessel stenosis post-clipping.</div></div><div><h3>Methods</h3><div>PubMed, Embase, Cochrane, and Web of Science databases were searched for studies reporting on FNa-VA for intraoperative aneurysm clipping assessment. We assessed the rate of mis-clippings identified by FNa-VA, false negatives, and procedure-related side effects. A diagnostic assessment analyzed FNa-VA’s sensitivity, specificity, PPV, and NPV. Single proportion analysis with 95% confidence intervals under a random effects model was used, with heterogeneity examined via I2 and leave-one-out analysis.</div></div><div><h3>Results</h3><div>Eight studies involving 280 patients with 311 aneurysms were included. FNa-VA identified mis-clippings that eluded visual inspection in 11.94 % of cases (95 % CI: 5.83–18.05, I<sup>2</sup> = 59 %), with false negatives in 2.15 % (95 % CI: 0–5.13, I<sup>2</sup> = 44 %). It has demonstrated a sensitivity of 50 % and a specificity of 93 %, with PPV and NPV of 52 % and 93 %, respectively. Procedure-related side effects were yellow skin and green urine for 2–3 days following the procedure.</div></div><div><h3>Conclusion</h3><div>FNa-VA may reduce the risk of mis-clipping during aneurysm surgery, however, it is still prone to false negatives and should be considered a complementary tool rather than used alone. Additionally, it appears to have a safe profile with only mild and transitory side effects.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"134 ","pages":"Article 111081"},"PeriodicalIF":1.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-28DOI: 10.1016/j.jocn.2025.111074
Janis B. Li , Jeffrey M. Katz , Brendan Huang
Epilepsy is one of the most common neurologic conditions in the world. Surgical treatment for refractory epilepsy is a method to optimize the quality of life for patients. Throughout his medical career, Dr. Wada examined the underlying mechanism of epilepsy and developed procedures to improve outcomes for his patients. A literature search of articles was conducted via PubMed and Google Scholar to chronicle the personal and professional life of Juhn Atsushi Wada. The review focused on Dr. Wada’s epilepsy research and the development of the carotid amytal injection, today known as the Wada test. In 1924, Juhn Atsushi Wada was born in Tokyo, Japan where he eventually attended Hokkaido Imperial University for his medical education. After completing his medical degree in 1947, Dr. Wada began his neurology and neurosurgery career in a war-torn Japan at the Hokkaido Imperial University Hospital. He developed the Wada test, an intracarotid sodium amytal injection, and published his landmark manuscript in 1949 that featured the observed benefits of the procedure and its suggested mechanisms of epilepsy. Wada would later move to North America, where he would disseminate his technique and lead the field in treating and understanding epilepsy. The contributions of Juhn Atsushi Wada earned him recognition as a leader in the fields of epilepsy neurosurgery and neurology.
{"title":"Juhn Atushi Wada (1924–2023) and the history of the Wada test","authors":"Janis B. Li , Jeffrey M. Katz , Brendan Huang","doi":"10.1016/j.jocn.2025.111074","DOIUrl":"10.1016/j.jocn.2025.111074","url":null,"abstract":"<div><div>Epilepsy is one of the most common neurologic conditions in the world. Surgical treatment for refractory<!--> <!-->epilepsy is a method to optimize the quality of life for patients. Throughout his medical career, Dr. Wada examined the underlying mechanism of epilepsy and developed procedures to improve outcomes for his patients. A literature search of articles was conducted via PubMed and Google Scholar to chronicle the personal and professional life of Juhn Atsushi Wada. The review focused on Dr. Wada’s epilepsy research and the development of the carotid amytal injection, today known as the Wada test. In 1924, Juhn Atsushi Wada was born in Tokyo, Japan where he eventually attended Hokkaido Imperial University for his medical education. After completing his medical degree in 1947, Dr. Wada began his neurology and neurosurgery career in a war-torn Japan at the Hokkaido Imperial University Hospital. He developed the Wada test, an intracarotid sodium amytal injection, and published his landmark manuscript in 1949 that featured the observed benefits of the procedure and its suggested mechanisms of epilepsy. Wada would later move to North America, where he would disseminate his technique and lead the field in treating and understanding epilepsy. The contributions of Juhn Atsushi Wada earned him recognition as a leader in the fields of epilepsy neurosurgery and neurology.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"134 ","pages":"Article 111074"},"PeriodicalIF":1.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-28DOI: 10.1016/j.jocn.2025.111087
Stephen Ahn, Jae Sung Park, Chul Bum Cho, Seung Ho Yang, Young Il Kim
{"title":"Corrigendum to \"Impact of anesthesia type on surgical outcomes and medical complications in chronic subdural hematoma surgery\" [J. Clin. Neurosci. 129 (2024) 110876].","authors":"Stephen Ahn, Jae Sung Park, Chul Bum Cho, Seung Ho Yang, Young Il Kim","doi":"10.1016/j.jocn.2025.111087","DOIUrl":"https://doi.org/10.1016/j.jocn.2025.111087","url":null,"abstract":"","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":" ","pages":"111087"},"PeriodicalIF":1.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-28DOI: 10.1016/j.jocn.2025.111090
Nicholas Kendall , Abdelrahman M Hamouda , Mark Cwajna , Aryan Gajjar , Mohamed Derhab , Sherief Ghozy , Kogulavadanan Arumaithurai , David F Kallmes
Background
For unruptured intracranial aneurysms (UIAs), conservative management is often possible. However, when direct treatment is warranted, endovascular treatments (EVTs) provide an effective minimally invasive approach. These procedures still necessitate careful patient monitoring, frequently in the Intensive Care Unit (ICU). The factors leading to ICU admission for these patients remains an area of debate.
Objective
This systematic review aims to highlight existing literature and identify gaps in understanding the factors contributing to ICU admission following EVTs for UIAs.
Methods
We utilized the Nested Knowledge Autolit semi-automated software to gather studies published before April 2024. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and included studies that met predetermined population, intervention, control, and outcomes (PICO) criteria. Statistical analysis was performed using R software.
Results
We retrieved 181 studies and 9 met our inclusion criteria. There was significant variability across these studies on what factors they reported. Across included studies there were 8,189 patients, with 5,620 being placed in the ICU following EVTs for UIAs. Analysis revealed that anterior aneurysm location, aneurysm-related symptoms, and procedure length were significant factors associated with ICU admission. The overall ICU admission rate was approximately 24.61 per 100 patients.
Conclusion
This review underscores the need for further research to understand the factors we found associated with ICU admission following EVTs for UIAs. Additional studies are needed that use a standardized approach to collect data on patient demographics, aneurysm characteristics, procedural details, and postoperative outcomes. Such studies will allow for concrete recommendations to be made on ICU needs and prognostic calculators to be developed in order to support clinical decisions and lower healthcare costs.
{"title":"Factors associated with ICU stays after endovascular treatments for unruptured intracranial aneurysms: A review study","authors":"Nicholas Kendall , Abdelrahman M Hamouda , Mark Cwajna , Aryan Gajjar , Mohamed Derhab , Sherief Ghozy , Kogulavadanan Arumaithurai , David F Kallmes","doi":"10.1016/j.jocn.2025.111090","DOIUrl":"10.1016/j.jocn.2025.111090","url":null,"abstract":"<div><h3>Background</h3><div>For unruptured intracranial aneurysms (UIAs), conservative management is often possible. However, when direct treatment is warranted, endovascular treatments (EVTs) provide an effective minimally invasive approach. These procedures still necessitate careful patient monitoring, frequently in the Intensive Care Unit (ICU). The factors leading to ICU admission for these patients remains an area of debate.</div></div><div><h3>Objective</h3><div>This systematic review aims to highlight existing literature and identify gaps in understanding the factors contributing to ICU admission following EVTs for UIAs.</div></div><div><h3>Methods</h3><div>We utilized the Nested Knowledge Autolit semi-automated software to gather studies published before April 2024. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and included studies that met predetermined population, intervention, control, and outcomes (PICO) criteria. Statistical analysis was performed using R software.</div></div><div><h3>Results</h3><div>We retrieved 181 studies and 9 met our inclusion criteria. There was significant variability across these studies on what factors they reported. Across included studies there were 8,189 patients, with 5,620 being placed in the ICU following EVTs for UIAs. Analysis revealed that anterior aneurysm location, aneurysm-related symptoms, and procedure length were significant factors associated with ICU admission. The overall ICU admission rate was approximately 24.61 per 100 patients.</div></div><div><h3>Conclusion</h3><div>This review underscores the need for further research to understand the factors we found associated with ICU admission following EVTs for UIAs. Additional studies are needed that use a standardized approach to collect data on patient demographics, aneurysm characteristics, procedural details, and postoperative outcomes. Such studies will allow for concrete recommendations to be made on ICU needs and prognostic calculators to be developed in order to support clinical decisions and lower healthcare costs.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"134 ","pages":"Article 111090"},"PeriodicalIF":1.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-28DOI: 10.1016/j.jocn.2025.111073
Mitchell Andrews , Antonio Di Ieva
Purpose
This literature review aims to synthesise current research on the application of artificial intelligence (AI) for the segmentation of brain neuroanatomical structures in magnetic resonance imaging (MRI).
Methods
A literature search was conducted using the databases Embase, Medline, Scopus, and Web of Science, and captured articles were assessed for inclusion in the review. Data extraction was performed for the summary of the AI model used, and key findings of each article, advantages and disadvantages were identified.
Results
Following full-text screening, 21 articles were included in the review. The review covers models for segmentation models applied to the whole brain, cerebral cortex, subcortical structures, the cerebellum, blood vessels, perivascular spaces, and the ventricles. Accuracy of segmentation was generally high, particularly for segmenting neuroanatomical structures in healthy cohorts.
Conclusion
The use of AI for automatic brain segmentation is generally highly accurate and fast for all regions of the human brain. Challenges include robustness to anatomical variability and pathology, largely due to difficulties with accessing sufficient training data.
{"title":"Artificial intelligence for brain neuroanatomical segmentation in magnetic resonance imaging: A literature review","authors":"Mitchell Andrews , Antonio Di Ieva","doi":"10.1016/j.jocn.2025.111073","DOIUrl":"10.1016/j.jocn.2025.111073","url":null,"abstract":"<div><h3>Purpose</h3><div>This literature review aims to synthesise current research on the application of artificial intelligence (AI) for the segmentation of brain neuroanatomical structures in magnetic resonance imaging (MRI).</div></div><div><h3>Methods</h3><div>A literature search was conducted using the databases Embase, Medline, Scopus, and Web of Science, and captured articles were assessed for inclusion in the review. Data extraction was performed for the summary of the AI model used, and key findings of each article, advantages and disadvantages were identified.</div></div><div><h3>Results</h3><div>Following full-text screening, 21 articles were included in the review. The review covers models for segmentation models applied to the whole brain, cerebral cortex, subcortical structures, the cerebellum, blood vessels, perivascular spaces, and the ventricles. Accuracy of segmentation was generally high, particularly for segmenting neuroanatomical structures in healthy cohorts.</div></div><div><h3>Conclusion</h3><div>The use of AI for automatic brain segmentation is generally highly accurate and fast for all regions of the human brain. Challenges include robustness to anatomical variability and pathology, largely due to difficulties with accessing sufficient training data.</div></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"134 ","pages":"Article 111073"},"PeriodicalIF":1.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-28DOI: 10.1016/j.jocn.2025.111078
Paul Arjanto
{"title":"Breaking barriers: The impact of felt stigma on stroke survivors' quality of life and pathways to holistic rehabilitation.","authors":"Paul Arjanto","doi":"10.1016/j.jocn.2025.111078","DOIUrl":"https://doi.org/10.1016/j.jocn.2025.111078","url":null,"abstract":"","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":" ","pages":"111078"},"PeriodicalIF":1.9,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-27DOI: 10.1016/j.jocn.2025.111060
Paul Arjanto, Mint Husen Raya Aditama
{"title":"Revolutionizing spine health: Bridging lifestyle interventions and inclusive care for global well-being.","authors":"Paul Arjanto, Mint Husen Raya Aditama","doi":"10.1016/j.jocn.2025.111060","DOIUrl":"https://doi.org/10.1016/j.jocn.2025.111060","url":null,"abstract":"","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":" ","pages":"111060"},"PeriodicalIF":1.9,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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