Journal of dentistry最新文献

{"title":"Comparison of the accuracy of Robotic arm and Dynamic Navigation in the placement of mandibular dental implants: An in-vitro study","authors":"Bander N. Al-Meshary ,&nbsp;Mohammed Y. Al-Jarsha ,&nbsp;Kurt B Naudi ,&nbsp;Ashraf Ayoub","doi":"10.1016/j.jdent.2026.106527","DOIUrl":"10.1016/j.jdent.2026.106527","url":null,"abstract":"<div><h3>Objective</h3><div>To compare the spatial accuracy between Robotic Computer-Assisted implant Surgery (R-CAIS) and Dynamic Computer-Assisted Implant Surgery (D-CAIS) for placement of dental implants.</div></div><div><h3>Methods</h3><div>The study was carried out on twelve polyurethane mandibular models which were randomly divided into two groups (n = 6): D-CAIS (group 1) and R-CAIS (group 2). In group 1 the placement of two mandibular implants was carried out manually guided by dynamic navigation. In group 2, the placement of the two mandibular implants was achieved using a robotic arm. The postoperative Cone Beam Computed Tomography (CBCT) scans were superimposed on the predication planning to calculate the errors of the placement of the implants at entry point and at the apex as well as any angulation deviation. The statistical significance of the placement errors was assessed using Student <em>t</em>-tests and Mann–Whitney U tests (<em>p</em> &lt; 0.05) for parametric and non-parametric measurements, respectively.</div></div><div><h3>Results</h3><div>D-CAIS group cases showed significantly lower entry and apex deviations (0.99 ± 0.33 mm; 0.77 ± 0.34 mm) compared to the R-CAIS group (1.82 ± 0.50 mm; 1.30 ± 0.51 mm). Angular deviation was comparable between the two groups (3.97 ± 2.40° vs 4.33 ± 1.83°; <em>p</em> = 0.51). The standard deviations of the linear placement errors (entry and apex) were smaller in the D-CAIS group, whereas the standard deviation of the angular deviation was smaller in the R-CAIS group. Although the angular deviation differed slightly between the two approaches, the results showed no statistically significant difference. The measured implant placement errors of the two approaches were clinically acceptable (&lt; 2 mm; <strong>&lt;</strong> 5°). The measured errors are likely to be secondary to the registration process which was more complex with the application of the robotic arm for the placement of the implants.</div></div><div><h3>Conclusion</h3><div>D-CAIS demonstrated higher accuracy in mandibular implant placement, particularly in terms of linear deviations, while R-CAIS showed greater consistency in angular measurements despite no significant difference between groups. Overall, the observed deviations were small and are of limited clinical significance. These findings reflect system-level performance in a controlled laboratory setting, further clinical studies are required to validate these results.</div></div><div><h3>Clinical significance</h3><div>The study investigated the challenges and opportunities of the clinical application of dynamic navigation and robotic arm for the placement of dental implants. It informs the reader with the related technical details and the digital workflow for each of these two innovative techniques.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"167 ","pages":"Article 106527"},"PeriodicalIF":5.5,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146093287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial and demineralisation-inhibiting properties of silver complex fluoride on dentine caries: an in vitro study","authors":"Grace Y Xu ,&nbsp;Iris X Yin ,&nbsp;Irene S Zhao ,&nbsp;Christie YK Lung ,&nbsp;Edward CM Lo ,&nbsp;Chun Hung Chu","doi":"10.1016/j.jdent.2026.106528","DOIUrl":"10.1016/j.jdent.2026.106528","url":null,"abstract":"<div><h3>Objective</h3><div>The objective of this study was to investigate the antibacterial and demineralisation-inhibiting effects of a non-discolouring silver complex fluoride (SCF) on artificial dentine caries.</div></div><div><h3>Methods</h3><div>Dentine blocks with artificial carious lesions were treated with SCF, silver diamine fluoride (SDF, as positive control), and water (as negative control). Then the blocks underwent <em>Streptococcus mutans</em> biofilm and pH–cycling for 7 days. The morphology, viability and growth kinetics of the biofilm were evaluated by scanning electron microscopy (SEM), confocal laser scanning microscopy (CLSM) and colony-forming unit (CFU) counting, respectively. The dentine surface morphology, lesion depths and mineral loss, chemical structure and crystal characteristics were determined using SEM, micro-computed tomography, Fourier transform infrared (FTIR), and X-ray diffraction (XRD), respectively. One-way analysis of variance with the Bonferroni post hoc test was performed to assess and compare the data.</div></div><div><h3>Results</h3><div>SEM revealed confluent bacterial growth covering the surface of dentine treated with water but not SCF and SDF. CLSM showed that the dead-to-live ratios of biofilms treated with SCF, SDF, and water were 0.77 ± 0.16, 0.88 ± 0.40, and 0.44 ± 0.03, respectively (<em>p</em> &lt; 0.001, SCF, SDF&gt;Water). The Log CFU values of the biofilm treated with SCF, SDF and water were 6.7 ± 0.1, 6.6 ± 0.2 and 7.8 ± 0.1 (<em>p</em> &lt; 0.001, SCF, SDF&lt;Water). SEM images showed Group SCF had less exposed dentine collagen fibers than Group Water. Micro-computed tomography showed the lesion-depth (μm) of dentine treated with SCF, SDF and water were 40±5, 35±8 and 180±20 (<em>p</em> &lt; 0.001, SCF, SDF&lt;Water). The mineral loss (gHApcm⁻³) of dentine treated with SCF, SDF and water were 0.24±0.05, 0.20±0.03 and 0.45±0.03 (<em>p</em> &lt; 0.001, SCF, SDF&lt;Water). FTIR showed the amide I-to-hydrogen phosphate ratios of dentine treated with SCF, SDF and water were 0.25±0.03, 0.22±0.03, and 0.43±0.05 (<em>p</em> &lt; 0.001, SCF, SDF&lt;Water). XRD revealed that the hydroxyapatite in SDF and SCF groups was better crystallised than that of water Group.</div></div><div><h3>Conclusion</h3><div>This study demonstrated that SCF inhibited the growth of <em>S. mutans</em> biofilm and reduced the demineralisation of artificial dentine caries.</div></div><div><h3>Clinical significance</h3><div>If SCF is successfully translated into clinical application, it may be a novel anti-caries agent for clinicians to arrest dentine caries</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"167 ","pages":"Article 106528"},"PeriodicalIF":5.5,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between single point aMMP8 levels and previous periodontal disease progression – a long-term follow-up after 10 years in patients with stage III/IV periodontitis","authors":"Sophie Gänesch ,&nbsp;Caspar Victor Bumm ,&nbsp;Florian Nagler ,&nbsp;Christina Ern ,&nbsp;Richard Heym ,&nbsp;Iris Frasheri ,&nbsp;Thomas Spinell ,&nbsp;Charlotte Wetzel ,&nbsp;Julia Diegelmann ,&nbsp;Vinay Pitchika ,&nbsp;Falk Schwendicke ,&nbsp;Nils Werner ,&nbsp;Matthias Folwaczny","doi":"10.1016/j.jdent.2026.106526","DOIUrl":"10.1016/j.jdent.2026.106526","url":null,"abstract":"<div><h3>Background</h3><div>To investigate the association of active matrix-metalloproteinase-8 (aMMP-8) levels in total oral fluid (TOF), gingival crevicular fluid (GCF) and periodontal disease progression in the last 10 years in a cohort of patients with stage III/IV periodontitis.</div></div><div><h3>Methods</h3><div>47 patients receiving steps 1 and 2 of periodontal therapy with an observation period of over 10 years were included. Levels of current aMMP-8 in TOF, GCF and serum were determined at a single point at the ten-year follow-up. Past periodontal disease progression was characterized by clinical attachment loss over 10 years. For statistical analysis, linear regression models along with binary logistic regression models to analyze the progression rate based on age, gender, smoking, diabetes, full mouth bleeding score (FMBS), and T2 aMMP-8 levels were performed.</div></div><div><h3>Results</h3><div>At T2, the median patient age was 73 years [67; 79], with a mean attachment loss of 1.5 mm [1.0; 2.1] over the observation period. aMMP-8 levels did not differ between patients with mild and moderate disease progression. In multivariate linear regression, aMMP-8 levels were not associated with mean attachment loss. In contrast, sex, non-smoking status, and FMBS showed significant associations with past progression. Classification models for GCF and serum aMMP-8 expression yielded the highest accuracy (ROC = 0.80) for the binary assessment into mild and moderate progression, although this did not differ significantly from the model based on covariates alone (ROC = 0.75).</div></div><div><h3>Conclusion</h3><div>Current aMMP-8 levels determined at a single point were not associated with past periodontal disease progression during a 10-year period. Clinical factors such as sex, non-smoking status, and FMBS showed a stronger association with past progression.</div></div><div><h3>Clinical Significance</h3><div>Biomarkers might improve the precision of periodontal diagnosis and monitoring; however, evidence is limited regarding their association with disease progression. Active-MMP-8 has gained increasing interest in recent years.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"167 ","pages":"Article 106526"},"PeriodicalIF":5.5,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial aging-induced changes in surface properties of experimental bioactive glass-containing composites","authors":"Matej Par ,&nbsp;Andrea Gubler ,&nbsp;Danijela Marovic ,&nbsp;Zrinka Tarle ,&nbsp;Thomas Attin ,&nbsp;Tobias T. Tauböck","doi":"10.1016/j.jdent.2026.106525","DOIUrl":"10.1016/j.jdent.2026.106525","url":null,"abstract":"<div><h3>Objective</h3><div>To determine how artificial aging affects microhardness (MH), surface roughness (Ra), and surface micromorphology of experimental bioactive glass (BG)-containing resin composites functionalized with either conventional BG 45S5 (C-series) or a low-sodium fluoride-containing BG (F-series).</div></div><div><h3>Methods</h3><div>Seven experimental composites were prepared (Control; 5, 10, 20 wt% BG within each series; total filler load 70 wt%) based on a Bis-GMA/TEGDMA (60:40) resin matrix. Light-cured composite specimens were aged in simulated body fluid (SBF, pH 7.4), lactic acid solution (LA, pH 4.0), ethanol/water solution (75% EtOH), 0.1 M NaOH solution (pH 13.0), or thermocycled 10,000 cycles (5–55°C). MH and Ra were measured at baseline, 1, 3, 7, and 30 days, and specimen surfaces were examined by SEM/EDS. Ultrasonication was used to remove loosely bound surface deposits, after which MH, Ra, and SEM/EDS were re-measured.</div></div><div><h3>Results</h3><div>MH degradation ranked SBF&lt;LA&lt;EtOH&lt; NaOH. In the C-series, MH declined with increasing content of BG 45S5 under all aging conditions. In contrast, the F-series (5–20 wt%) maintained MH values statistically similar to Control in SBF, LA, EtOH, and after thermocycling. Ra increased for BG-containing materials in SBF, LA, EtOH, and after thermocycling, whereas NaOH significantly increased Ra for all materials, including Control. After ultrasonication, all F-series Ra values were below 0.2 µm, indicating clinically acceptable surface smoothness. SEM analysis showed apatite-like precipitates in SBF, dissolution pits in LA, interfacial cracking and occasional particle detachment in EtOH, and extensive filler loss with pronounced erosion in NaOH.</div></div><div><h3>Conclusions</h3><div>Under accelerated aging, F-BG composites maintained MH and clinically acceptable smoothness more reliably than 45S5 formulations, with limited roughening under neutral and mildly acidic conditions.</div></div><div><h3>Clinical relevance</h3><div>Composites with low-sodium fluoride-containing BG maintained microhardness comparable to the control composite and post-ultrasonication roughness below 0.2 µm, supporting their potential as ion-releasing restoratives with clinically acceptable surfaces.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"167 ","pages":"Article 106525"},"PeriodicalIF":5.5,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146085972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioactive and antibacterial universal adhesives containing ZnO/Cu and bioactive glass nanoparticles","authors":"Carolina Pardo-Díaz ,&nbsp;Gabriel Cochinski ,&nbsp;Pedro Moreira ,&nbsp;Fabio Dupart Nascimento ,&nbsp;Marina Damasceno e Souza Chiari ,&nbsp;Joatan Lucas de Sousa Gomes Costa ,&nbsp;Cristian Covarrubias ,&nbsp;Mario Felipe Gutiérrez ,&nbsp;Alessandro D. Loguercio ,&nbsp;Eduardo Fernández","doi":"10.1016/j.jdent.2026.106524","DOIUrl":"10.1016/j.jdent.2026.106524","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the antibacterial activity, cytocompatibility, mineralizing potential, degree of conversion (DC), enzymatic activity, and resin–dentin microtensile bond strength (μTBS) of a universal adhesive modified with zinc oxide (ZnO), copper (Cu), and bioactive glass (BG) nanoparticles.</div></div><div><h3>Methods</h3><div>Five adhesive formulations were evaluated: control (0 wt %); ZnO/Cu (0.2 wt % Cu + 2.5 wt % ZnO); 5 wt %BG + ZnO/Cu; 10 wt %BG + ZnO/Cu; and 10 wt %BG. Antibacterial activity against Streptococcus mutans was quantified by colony-forming unit counts. Cytocompatibility was assessed using human gingival stem cells (MTS assay, 3 and 7 days). Mineralization was evaluated after immersion in simulated body fluid (7 and 28 days) via FE-SEM and EDX. The DC was measured by Raman spectroscopy. Resin–dentin μTBS was tested under self-etch (SE) and etch-and-rinse (ER) strategies. MMPs activity was assessed by in situ zymography. Data were analyzed with ANOVA and Tukey tests (α = 0.05).</div></div><div><h3>Results</h3><div>BG nanoparticles significantly enhanced antibacterial and mineralizing responses. The 10 wt %BG and 10 wt %BG + ZnO/Cu groups achieved &gt;80 % bacterial inhibition and marked Ca–P deposition after 28 days. All adhesives exhibited cytocompatibility (&gt;80 % viability) and DC values &gt;60 %. A slight reduction in μTBS was observed for 10 wt %BG groups under the ER strategy. High gelatinolytic activity was detected across all groups, with reduced fluorescence only for the ZnO /Cu group under ER strategy.</div></div><div><h3>Conclusions</h3><div>Incorporating BG nanoparticles into a ZnO/Cu-modified universal adhesive improved antibacterial and mineralizing properties without impairing cytocompatibility, polymerization, without critically compromising bond strength. MMP activity varied with bonding strategies, with no consistent inhibitory effect observed.</div></div><div><h3>Clinical Relevance</h3><div>Universal adhesives modified with bioactive glass and ZnO/Cu nanoparticles exhibited enhanced antibacterial and mineralizing properties while maintaining cytocompatibility and degree of conversion, without critically compromising bond strength. Although, no immediate inhibition of MMP activity was observed, this multifunctional approach may contribute to more stable adhesive interfaces and improved long-term performance of composite restorations.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"167 ","pages":"Article 106524"},"PeriodicalIF":5.5,"publicationDate":"2026-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146157294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Evaluation of an Automated Robotic System for Full Crown Preparation","authors":"Huayu Fang ,&nbsp;Heng Liu ,&nbsp;Chen Liu ,&nbsp;Yuanxue Gao ,&nbsp;Shiwei Song ,&nbsp;Junchen Wang ,&nbsp;Shizhu Bai ,&nbsp;Yimin Zhao","doi":"10.1016/j.jdent.2026.106520","DOIUrl":"10.1016/j.jdent.2026.106520","url":null,"abstract":"<div><h3>Objectives</h3><div>To develop a robotic system for full crown tooth preparation and to evaluate its preparation accuracy and operation time.</div></div><div><h3>Methods</h3><div>The robotic system comprised a robotic arm, an infrared optical tracking system, and proprietary planning/control software. The planning workflow encompassed path planning for axial and occlusal surfaces, functional cusp bevels, and acute line angles, culminating in the generation of an ideal preparation morphology. Twenty-two standardized partial dentition models of mandibular teeth 35–37 were additively manufactured and equally allocated into two experimental groups based on preparation methodology: an automated robotic system group and a step-by-step guide group. Operation time was recorded concurrently. Post-preparation scan data were imported into three-dimensional reverse engineering software to calculate the root-mean-square-error (RMSE) values for the overall surfaces, axial surfaces, occlusal surfaces, and chamfer regions to evaluate preparation accuracy.</div></div><div><h3>Results</h3><div>In the posterior crown preparation model experiment, the robotic group showed significantly lower RMSE values than the guide group overall and by region: overall, 0.18±0.03 vs 0.33±0.05 mm; axial, 0.15±0.06 vs 0.27±0.08 mm; occlusal, 0.20±0.05 vs 0.38±0.07 mm; chamfer, 0.12±0.03 vs 0.30±0.07 mm. The occlusal surface yielded the lowest accuracy in both groups. The robotic system also significantly reduced preparation time (350.15±7.79 s vs. 583.93±90.48 s), confirming its efficiency advantage.</div></div><div><h3>Conclusions</h3><div>This study developed an automated robotic system for crown preparation that demonstrated superior accuracy and shorter operation time compared with the guide approach.</div></div><div><h3>Clinical significance</h3><div>In this study, we developed a novel robotic system for full crown preparation that may enable precise and efficient procedures, representing a promising approach for achieving high-accuracy tooth preparation while minimizing tissue removal.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"167 ","pages":"Article 106520"},"PeriodicalIF":5.5,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146046751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An alternative radiation-free method for assessing the accuracy of robotic computer-assisted implant surgery: a cross-sectional study","authors":"Rongrong Zhu ,&nbsp;Longlong He ,&nbsp;Qin Zhou ,&nbsp;Meng Zhang ,&nbsp;Xiaofeng Chang ,&nbsp;Ningbo Zhao","doi":"10.1016/j.jdent.2026.106523","DOIUrl":"10.1016/j.jdent.2026.106523","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to assess the accuracy of implant placement performed using robotic computer-assisted implant surgery (r-CAIS) by comparing postoperative measurements obtained via intraoral scanning (IOS) with those derived from cone-beam computed tomography (CBCT).</div></div><div><h3>Methods</h3><div>The study employed a cross-sectional design. All patients received a preoperative CBCT and IOS for surgical planning and registration. All the surgeries were performed using r-CAIS. Postoperative CBCT and IOS datasets were acquired for each patient and superimposed on the preoperative datasets to assess deviations between planned and actual implant positions. Paired t-tests were used to analyze differences between the two assessment modalities, with statistical significance defined as <em>P</em> &lt; 0.05. Agreement between the two methods was evaluated using intra-class correlation coefficients (ICCs) and Bland–Altman analyses.</div></div><div><h3>Results</h3><div>Thirty-four implants in twenty-seven patients were included. Global coronal, global apical, and angular deviations measured using the IOS method were 0.59 ± 0.23 mm, 0.66 ± 0.24 mm, and 1.28 ± 0.69°, respectively, compared with 0.59 ± 0.24 mm, 0.63 ± 0.25 mm, and 1.19 ± 0.70° measured by the CBCT method. No statistically significant differences were observed between the two modalities (<em>P</em> &gt; 0.05, respectively). ICCs for global coronal, global apical, and angular deviations were 0.911, 0.886, and 0.856, respectively. Bland–Altman analyses further confirmed excellent agreement between the two methods.</div></div><div><h3>Conclusions</h3><div>Both IOS and CBCT methods demonstrated comparable accuracy and good agreement in r-CAIS.</div></div><div><h3>Clinical significance</h3><div>Postoperative IOS method may serve as a reliable and radiation-free alternative to CBCT for assessing implant placement accuracy in r-CAIS in patients with a single missing tooth or two consecutive missing teeth. In future, multicenter randomized controlled trials with larger sample sizes are warranted to further validate these findings.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"167 ","pages":"Article 106523"},"PeriodicalIF":5.5,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146046745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Training, beliefs, and perceived barriers to implementing sustainable dentistry: influence of practitioners’ age, gender, and practice size – Results from a French online survey","authors":"Valérie Szönyi ,&nbsp;Jean-Noël Vergnes ,&nbsp;Maïlys Campus ,&nbsp;Alice Baras ,&nbsp;Benoît Perrier ,&nbsp;Laurent Laforest ,&nbsp;Brigitte Grosgogeat","doi":"10.1016/j.jdent.2026.106521","DOIUrl":"10.1016/j.jdent.2026.106521","url":null,"abstract":"<div><h3>Methods</h3><div>Despite the sizable environmental footprint of oral healthcare, evidence on dentists’ training, beliefs, and perceived implementation barriers on sustainable dentistry —especially across practitioner subgroups—remains limited. We assessed among French dentists these outcomes and their variations by age, gender, and practice size.</div><div>We conducted a cross-sectional online survey (April 5–June 23, 2023) distributed via professional networks to dentists in France. Analyses were restricted to dental practitioners aged 25 years and over. Outcomes were modelled with multivariable logistic regression for associations with age, gender, and practice size.</div></div><div><h3>Results</h3><div>While 92.3 % of the 651 participants (median age = 45 years, 60.8 % women) were concerned by the environmental consequences of their activity, only 40.8 % had implemented concrete actions. Only 2.3 % had received university-level training and 5.8 % any continuing education in sustainable dentistry; 31.6 % were aware of continuing education opportunities. The main reported barriers were lack of professional information (66.0 %), time constraints (60.8 %), and financial costs (56.8 %). Compared to younger practitioners, those aged 40-49 years and ≥ 50 years were more likely to have implemented concrete actions (OR=1.92, 95 %CI=[1.24-2.98] and OR=1.78, 95 %CI=[1.15-2.76], respectively). Responders in larger practices (&gt;4 practitioners) more often reported time constraints (OR=3.37, 95 %CI=[1.84-6.15]), the lack of interest of the team (OR=1.87, 95 %CI=[1.07-3.24) and less likely cost-related issues (OR=0.57, 95 %CI=[0.33-0.99]).</div></div><div><h3>Conclusions</h3><div>Despite widespread concern, sustainable practices remain under-implemented. Large education gaps and limited guidance are prominent, and perceived barriers differ by age and practice structure. Targeted training, tailored implementation support, and organizational change strategies are needed to accelerate the transition to sustainable dentistry.</div></div><div><h3>Clinical Significance</h3><div>Understanding dentists’ training needs, beliefs, and perceived barriers to sustainable dentistry is crucial to accelerating its integration into clinical practice. Identifying subgroup differences by age, gender, and practice size enables the development of targeted education and tailored support, facilitating eco-responsible practices and improving dentistry’s contribution to global health.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"166 ","pages":"Article 106521"},"PeriodicalIF":5.5,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146044012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saliva and salivary pellicle composition and proteomic profile in smokers vs. non-smokers and its effect on dental erosion","authors":"Philipp Kanzow ,&nbsp;Christof Lenz ,&nbsp;Frederike Schlarmann ,&nbsp;Sarah Barke ,&nbsp;Bianca Rohland ,&nbsp;Alexandra Schmidt ,&nbsp;Anastasiia Gorshkova ,&nbsp;Lisa Neuenroth ,&nbsp;Annette Wiegand","doi":"10.1016/j.jdent.2026.106517","DOIUrl":"10.1016/j.jdent.2026.106517","url":null,"abstract":"<div><h3>Objective</h3><div>To analyse the salivary composition and proteomic profile of saliva and the salivary pellicle in smokers compared to non-smokers, and to examine potential differences in the erosion-protective capacity of the salivary pellicle.</div></div><div><h3>Methods</h3><div>Twenty-five smokers and 25 non-smokers were included. Unstimulated and stimulated saliva samples were analysed regarding flow rate, pH, buffer capacity, calcium, phosphate, fluoride, and protein content. Saliva and salivary pellicle samples were analysed by data-independent acquisition mass spectrometry (DIA-MS) for proteome profiling. In an in situ experiment, intraoral splints were loaded with bovine enamel and dentine specimens for 120 min. Pellicle-covered specimens were extraorally eroded (HCl, pH 2.3, 60 s). Calcium release was determined photometrically and compared to pellicle-free controls.</div></div><div><h3>Results</h3><div>Except for phosphate in stimulated saliva (p_adj.=0.003), salivary parameters were not significantly different between smokers and non-smokers. Proteome profiling detected 1759±154 proteins (cumulative 1963) in saliva, and 4262±362 proteins (cumulative 4625) in the salivary pellicle. The relative abundances of 282 (unstimulated saliva), 338 (stimulated saliva), and 4 (salivary pellicle) protein groups differed significantly between smokers and non-smokers. Functional enrichment analysis of differentially abundant human proteins revealed biological processes such as coagulation, immune response, and carcinogenic reactive oxygen species processes to be impacted by smoking. The salivary pellicle had a significant erosion-protective effect in enamel compared to the control (41.4 ± 6.3 nmol/mm²), but no differences between smokers (33.2 ± 10.6 nmol/mm², p_adj.=0.001) and non-smokers (32.7 ± 8.6 nmol/mm², p_adj.=0.001) were found.</div></div><div><h3>Conclusion</h3><div>The proteomic profiles of both unstimulated and stimulated saliva and the salivary pellicle differ between smokers and non-smokers.</div></div><div><h3>Clinical significance</h3><div>Despite the different proteomic profiles indicating a significant impact of smoking on the oral cavity, the erosion-protective capacity of the salivary pellicle of smokers and non-smokers does not differ.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"166 ","pages":"Article 106517"},"PeriodicalIF":5.5,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146040881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical evaluation and bone loss prediction of titanium-zirconium implants: A retrospective study of 1-5-year follow-up","authors":"Zhaoting Ling ,&nbsp;Cong Chen ,&nbsp;Siyuan Wang ,&nbsp;Yun Zhu ,&nbsp;Xiaoting Shen ,&nbsp;Kefang Sun ,&nbsp;Hongye Lu ,&nbsp;Fuming He","doi":"10.1016/j.jdent.2026.106516","DOIUrl":"10.1016/j.jdent.2026.106516","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the clinical and radiographic outcomes of titanium-zirconium implants, identify risk factors and develop predictive models for bone loss progression.</div></div><div><h3>Methods</h3><div>Patients with titanium-zirconium implants were screened for inclusion and underwent follow-ups. Cumulative survival rates at the implant and patient levels were calculated using life tables. Clinical and radiographic data were retrospectively analyzed for implant/restoration success rates and peri-implant marginal bone loss. Factors influencing marginal bone loss were examined using generalized estimating equations (GEE). Support vector machine (SVM), artificial neural network (ANN), logistic regression (LR), and random forest (RF) were used to develop the prediction models of bone loss.</div></div><div><h3>Results</h3><div>573 titanium-zirconium implants from 399 patients were included, with an average observation time of 27.6 ± 11.5 months (12-63 months). The cumulative 5-year survival rate was 99.1% at the implant level, and 98.8% at the patient level. The mean probing depth was 3.1 ± 1.2 mm, with 23.6% incidence of bleeding on probing. The mean marginal bone loss was 0.37-0.52 mm. GEE analysis showed that marginal bone loss was significantly influenced by follow-up time, advanced age, narrow-diameter implant, location, and fixed partial denture. LR and ANN models demonstrated optimal predictive performance, both with 93.5% accuracy. Baseline marginal bone level emerged as the most significant predictor, with an importance score of 41.3.</div></div><div><h3>Conclusions</h3><div>The 1-5-year outcomes revealed that titanium-zirconium implants achieved high survival and success rates, with limited marginal bone loss. The prediction model demonstrated 93.5% accuracy, identifying baseline marginal bone level as the primary determinant of bone loss progression.</div></div><div><h3>Clinical Significance</h3><div>Titanium-zirconium implants achieve satisfactory clinical outcomes and identifies the baseline marginal bone level as the primary determinant of bone loss progression. (clinical trial registration number: ChiCTR2300069888)</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"166 ","pages":"Article 106516"},"PeriodicalIF":5.5,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146040869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}