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Police vehicle contamination by inorganic gunshot residue (iGSR) in Zagreb County Police Administration (Croatia): Analysis of characteristic and indicative particles across different vehicle parts and contributory risk factors 萨格勒布县警察局(克罗地亚)警车受无机枪弹残留物 (iGSR) 污染的情况:对不同车辆部件的特征性和指示性颗粒以及促成风险因素的分析。
IF 1.5 4区 医学 Q2 MEDICINE, LEGAL Pub Date : 2024-09-15 DOI: 10.1111/1556-4029.15628
Hrvoje Senješ MSc, Sunčica Kuzmić MSc, Ivan Jerković PhD

Inorganic gunshot residue (iGSR) analysis, crucial for linking suspects to firearm use, faces challenges from potential environmental contamination, notably in police vehicles. The present study aimed to explore the level of iGSR contamination in police vehicles from the Zagreb County Police Administration (Croatia), considering particle types and their position in vehicles, and to identify associated risk factors. From December 2021 to April 2022, 65 of 86 police vehicles (margin of error: ±6% at a 95% confidence level) were sampled with GSR stubs on the drivers' seats, back seats, and backrests and analyzed using scanning electron microscopy and energy dispersive x-ray analysis (SEM/EDX). Characteristic particles were found in 63.1% of vehicles, 33.8% on the driver's seat, and 24.6% on the back seat/backrest. Indicative particles were found in 70.77% of vehicles, with a fairly even distribution. McNemar's chi-square analysis showed no significant disparities in positive sample ratios across vehicle parts or particle types (p > 0.05). In total, 228 characteristic and 166 indicative GSR particles were identified, with no notable correlation among them (p = 0.346). Logistic regression analysis identified the transportation of individuals involved in firearms incidents as a statistically significant factor influencing the presence of characteristic particles (p = 0.030). The findings suggest a considerable prevalence of iGSR in the analyzed Police Administration unit, highlighting the need for careful contamination management in police operations to preserve evidence integrity, particularly in cases when individuals who used firearms had been transported in the vehicle.

无机枪击残留物 (iGSR) 分析对于将嫌疑人与枪支使用联系起来至关重要,但却面临着潜在环境污染带来的挑战,尤其是警车内的环境污染。本研究旨在探讨萨格勒布县警察局(克罗地亚)警车中 iGSR 的污染程度,同时考虑粒子类型及其在车辆中的位置,并确定相关风险因素。2021 年 12 月至 2022 年 4 月,对 86 辆警车中的 65 辆(误差率:±6%,置信度为 95%)的驾驶员座椅、后座和靠背上的 GSR 存根进行了采样,并使用扫描电子显微镜和能量色散 X 射线分析 (SEM/EDX) 进行了分析。在 63.1%的车辆中发现了特征性颗粒,33.8%在驾驶员座椅上,24.6%在后座/靠背上。在 70.77% 的车辆中发现了指示性颗粒,分布相当均匀。McNemar's chi-square 分析表明,不同车辆部件或颗粒类型的阳性样本比率没有明显差异(P > 0.05)。总共确定了 228 个特征性 GSR 颗粒和 166 个指示性 GSR 颗粒,它们之间没有明显的相关性(p = 0.346)。逻辑回归分析表明,枪支事件中涉案人员的交通工具是影响特征颗粒出现的一个具有统计学意义的因素(p = 0.030)。研究结果表明,iGSR 在所分析的警察行政单位中相当普遍,这突出表明在警察行动中需要谨慎管理污染,以保持证据的完整性,尤其是在使用枪支的人员被押送到车辆中的情况下。
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引用次数: 0
An analysis of 105 female-perpetrated mass murders 对 105 起女性实施的大规模谋杀案的分析
IF 1.5 4区 医学 Q2 MEDICINE, LEGAL Pub Date : 2024-09-11 DOI: 10.1111/1556-4029.15627
Ragy R. Girgis MD, Dung Hoang MA, Hannah Hesson BA, Gabriella Dishy MA, Kathryn Lee MA, Tyler Pia MA, Faizan Syed MD, Alexandra Villalobos MA, Paul S. Appelbaum MD, Gary Brucato PhD

Most research on mass murderers to date has focused on perpetrators of male sex, while research on perpetrators of female sex has been relegated to case reports and series. We aimed to more fully examine the phenomenon of female-perpetrated mass murder. We analyzed 1715 worldwide incidents of personal-cause mass murder from 1900 to 2019, identifying 105 (6%) events perpetrated by females. We defined mass murder as any event involving at least three fatalities, not including the perpetrator, using any method. We identified cases of mass murder from English-language databases of mass murder or murder in print or online. There were no significant differences in age and race between female and male perpetrators. Relative to males, female perpetrators were significantly less likely to employ firearms in their mass murders, using them in less than half of cases, compared to over 70% for males. The prevalence of psychotic signs and symptoms among female mass murderers was more than double that among males (25.7% vs. 12.5%, p < 0.01), while the rate of nonpsychotic psychiatric or neurological conditions was also much greater among female perpetrators (29.5% vs. 17.1%, p < 0.01). Over half of female perpetrators took or attempted to take their own lives. More than three-quarters of mass murders by females involved at least one family member as a victim. This study underscores sex-specific differences in the perpetration of mass murder and the need for further research to understand how insights about such dynamics might lead to the development of more effective and informed intervention policies.

迄今为止,有关大屠杀凶手的研究大多集中于男性罪犯,而对女性罪犯的研究则仅限于个案报告和系列研究。我们旨在更全面地研究由女性实施的大屠杀现象。我们分析了 1900 年至 2019 年全球发生的 1715 起个人原因的大规模屠杀事件,发现 105 起(6%)事件是由女性实施的。我们将大规模屠杀定义为使用任何方法造成至少三人死亡(不包括犯罪者)的任何事件。我们从大规模谋杀或印刷或在线谋杀的英文数据库中确定了大规模谋杀的案例。女性和男性犯罪者在年龄和种族上没有明显差异。与男性相比,女性犯罪者在大屠杀中使用枪支的可能性要低得多,只有不到一半的案件使用枪支,而男性使用枪支的比例则超过 70%。女性大屠杀凶手中精神病症状和体征的发生率是男性的两倍多(25.7% 对 12.5%,p < 0.01),而非精神病性精神病或神经系统疾病的发生率在女性凶手中也要高得多(29.5% 对 17.1%,p < 0.01)。半数以上的女性罪犯自杀或试图自杀。超过四分之三的女性大规模谋杀案涉及至少一名家庭成员作为受害者。这项研究强调了大规模屠杀犯罪中的性别差异,以及进一步研究的必要性,以了解对这种动态的洞察力可能会导致制定更有效和知情的干预政策。
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引用次数: 0
Evaluating cardiac risks of TASER: An in‐depth case study through probable current analysis 评估 TASER 的心脏风险:通过可能的电流分析进行深入案例研究
IF 1.6 4区 医学 Q2 MEDICINE, LEGAL Pub Date : 2024-09-11 DOI: 10.1111/1556-4029.15614
Hojeong Seo, Saehan Park, Sanghee Kim, Sookyoung Lee, Changho Choi
This study investigates the cardiac safety concerns related to TASER discharges centering on a pivotal case that marked the first TASER‐related fatality in South Korea. Employing Pratt et al.'s theoretical framework, the research evaluates the potential for ventricular fibrillation (VF) from these discharges. The methodology incorporated a high‐resolution waveform analysis using sophisticated equipment and considered specific incident details, including dart impact locations verified through a forensic examination. A human body impedance of 500 Ω, chosen based on empirical studies and coupled with non‐inductive resistance for high‐voltage handling, was utilized in the model. By applying a heart‐current factor from IEC 60479 standards, the study found a VF risk of up to 5% depending on the impact location and current pathways. In this specific case, although the calculated risk did not exceed critical thresholds, the VF risk was high enough to suggest that TASER discharges played a role in the fatal outcome. This study underscores the importance of dart impact location in TASER safety evaluations, contributing to a broader understanding of TASER cardiac risks and providing a basis to advocate for rigorous safety protocols.
本研究以韩国首例与 TASER 相关的死亡关键案例为中心,调查了与 TASER 发射有关的心脏安全问题。研究采用 Pratt 等人的理论框架,评估了这些放电造成心室颤动(VF)的可能性。该方法结合了使用精密设备进行的高分辨率波形分析,并考虑了具体的事件细节,包括通过法医检查核实的飞镖撞击位置。模型中使用了根据经验研究选择的 500 Ω 人体阻抗,并结合了用于高压处理的无感电阻。通过应用 IEC 60479 标准中的心脏电流系数,研究发现,根据撞击位置和电流路径,心房颤动风险最高可达 5%。在这个具体案例中,虽然计算出的风险没有超过临界阈值,但心房颤动风险很高,足以表明泰瑟放电在致命结果中起到了一定作用。这项研究强调了飞镖撞击位置在 TASER 安全评估中的重要性,有助于更广泛地了解 TASER 的心脏风险,并为倡导严格的安全协议提供依据。
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引用次数: 0
Poisoning with table salt while treating drug poisoning 治疗药物中毒时食盐中毒
IF 1.5 4区 医学 Q2 MEDICINE, LEGAL Pub Date : 2024-09-10 DOI: 10.1111/1556-4029.15623
Anna Smędra MD, PhD, Katarzyna Wochna DMD, PhD, Jacek Gruchała MD, PhD, Jarosław Berent MD, PhD

Hypernatremia is an increase in serum sodium concentration above 145 mmol/L. There are many causes of elevated sodium levels in the blood serum. One is incorrect actions performed by medical staff. The symptoms of excessively high serum sodium levels depend on the severity of hypernatremia, the rate of its increase and the accompanying volume disorders. Severe symptoms include altered consciousness, increased muscle tone and reflexes, convulsions, psychomotor hyperactivity or drowsiness (up to coma), respiratory failure, and even death. We present the case of a 45-year-old man who took seven tablets of a blood pressure-lowering drug, and paramedics subsequently administered a concentrated solution of table salt to induce vomiting. However, vomiting did not occur, leading to hypernatremia. Ultimately, the man survived but developed persistent cognitive dysfunction, including disordered short-term memory and encoding and retrieval of information from long-term memory, weakening of attention function and fatigue, and disorders in abstract thinking. The patient's family went to the prosecutor's office to investigate the possibility of medical malpractice. Experts found that the paramedics' actions were incorrect. Although it has been known for many years that table salt solutions should not be used to induce vomiting, unfortunately, both laypeople and medical professionals are still using this technique. Iatrogenic salt poisoning may end not only in serious health complications but also in legal consequences.

高钠血症是指血清钠浓度升高超过 145 毫摩尔/升。导致血清中钠浓度升高的原因有很多。其一是医务人员的错误操作。血清钠含量过高的症状取决于高钠血症的严重程度、升高速度和伴随的容量失调。严重的症状包括意识改变、肌张力和反射增强、抽搐、精神运动亢进或嗜睡(甚至昏迷)、呼吸衰竭,甚至死亡。我们介绍的病例中,一名 45 岁的男子服用了 7 片降压药,医护人员随后给他注射了食盐浓溶液催吐。然而,呕吐并没有发生,导致了高钠血症。最终,这名男子虽然活了下来,但出现了持续的认知功能障碍,包括短期记忆和长期记忆信息的编码和检索紊乱、注意力功能减弱和疲劳,以及抽象思维障碍。患者家属到检察院调查医疗事故的可能性。专家发现,医护人员的行为是错误的。尽管人们多年前就知道不应使用食盐溶液催吐,但遗憾的是,无论是普通人还是专业医务人员,仍然在使用这种方法。先天性盐中毒不仅可能导致严重的健康并发症,还可能导致法律后果。
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引用次数: 0
Patterns in paternal and maternal filicide: A comparative analysis of filicide cases in Turkey 杀父和杀母的模式:土耳其杀父和杀母案件的比较分析
IF 1.5 4区 医学 Q2 MEDICINE, LEGAL Pub Date : 2024-09-10 DOI: 10.1111/1556-4029.15625
Tuba Özcanlı MD, İhsan Okur MD, Cana Aksoy Poyraz MD, Neşe Kocabaşoğlu MD, Hızır Aslıyüksek MD

Filicide is the act of a parent killing their own offspring. Previous studies indicate that there are both commonalities and distinctions between filicides committed by mothers and fathers. The main objective of this study was to compare maternal and paternal filicide with a major focus on clinical and sociodemographic features of perpetrators, incident details, and victims. Filicide cases were examined at the bedded unit of the Expertise Department of Observation of the Council of Forensic Medicine that were referred by the Turkish Ministry of Justice. A total of 51 perpetrators and 57 victims were analyzed from June 2014 to December 2023. The perpetrators were daily face-to-face interviewed by psychiatry and forensic medicine physicians. There were significant differences in sociodemographic characteristics and psychiatric conditions between maternal and paternal cases. Female perpetrators tended to be younger, unemployed, mostly targeted younger victims and used asphyxiation to kill, whereas males tended to target older victims and utilized firearms. The most common primary cause of filicide in maternal cases was “unwanted pregnancy,” whereas “spousal revenge” and “anger or impulsivity” were predominant in paternal filicides. All perpetrators who were not criminally responsible were mothers, mostly diagnosed with psychotic depression. Unwanted pregnancy, psychotic depression, and postpartum psychosis should be assessed when evaluating risk for mothers, especially for infanticide. The desire for revenge on a spouse, often seen with personality disorders, impulsivity and anger, access to firearms should be screened for risk of paternal filicide, particularly in older victims. Early recognition of these factors can help in implementing prevention strategies.

弑父是父母杀害自己后代的行为。以往的研究表明,母亲和父亲的杀子行为既有共性,也有区别。本研究的主要目的是对母亲和父亲的弑亲行为进行比较,重点关注施暴者的临床和社会人口学特征、事件细节和受害者。法医学委员会观察专家部卧床病房对土耳其司法部转来的杀父杀母案件进行了研究。从 2014 年 6 月至 2023 年 12 月,共分析了 51 名行凶者和 57 名受害者。精神病学和法医学医生对施暴者进行了日常面对面访谈。母方和父方案件的社会人口特征和精神状况存在明显差异。女性行凶者往往更年轻、无业,大多以年龄较小的受害者为目标,并使用窒息手段杀人;而男性行凶者往往以年龄较大的受害者为目标,并使用枪支杀人。在母系变态杀人案中,最常见的主要原因是 "意外怀孕",而在父系变态杀人案中,则以 "配偶报复 "和 "愤怒或冲动 "为主。所有不负刑事责任的肇事者都是母亲,她们大多被诊断患有精神抑郁症。在评估母亲的风险,尤其是杀婴风险时,应评估意外怀孕、精神抑郁和产后精神病。对配偶进行报复的欲望通常表现为人格障碍、冲动和愤怒、获得枪支,因此应筛查父亲杀婴的风险,尤其是年龄较大的受害者。及早识别这些因素有助于实施预防战略。
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引用次数: 0
Visual detection and enhancement of alterations in questioned documents by Mueller polarimetry 利用穆勒偏振测量法对受质疑文件中的篡改进行视觉检测和增强。
IF 1.5 4区 医学 Q2 MEDICINE, LEGAL Pub Date : 2024-09-04 DOI: 10.1111/1556-4029.15617
Emanuel Chironi PhD, Claudio Iemmi PhD

In this article, we have explored the use of Mueller polarimetry for the detection and enhancement of alterations in questioned documents. Erasures, obliterations (with liquid paper and by pasting an additional layer of paper), and insertions (made with several inks) were studied in both regular and glossy paper. Promising results were obtained, which depend on the type of paper and the relation between the color of the ink and that of the illuminating light source. Erasures are easier to detect in glossy paper than in regular paper. Obliterations with liquid paper produced successful results in both types of paper, while detection of obliterations made with an additional layer of paper led to higher contrast for regular paper. Regarding the insertions, the black ball-point ink could be differentiated from roller-ball and gel-pen ink, which is often difficult to achieve visually. The contrast observed between the two inks was higher for regular paper than for glossy paper. Although the results shown in this article are promising, a wider variety of papers and pen types must be tested to further develop the procedure. It has the advantage of being non-destructive and far more economic than other methods. In some cases, the results can be complementary to those obtained by other methods (e.g., fluorescence with UV excitation and illumination with transmitted and oblique light), while in other cases the method offers unique advantages.

在这篇文章中,我们探讨了如何利用穆勒偏振测量法检测和增强被质疑文件中的改动。我们对普通纸和光面纸上的擦除、抹去(使用液体纸和粘贴一层纸)和插入(使用多种墨水)进行了研究。研究结果令人鼓舞,这取决于纸张的类型以及油墨颜色和照明光源颜色之间的关系。与普通纸相比,在光面纸上更容易发现擦除痕迹。用液体纸擦除在两种纸张上都能成功检测到,而用附加纸层检测擦除在普通纸上会产生更高的对比度。在插入方面,黑色圆珠笔墨水可以与滚珠笔和中性笔墨水区分开来,这在视觉上通常很难做到。在普通纸上观察到的两种墨水之间的对比度要高于光面纸。虽然本文显示的结果很有希望,但必须对更多种类的纸张和笔进行测试,以进一步开发该程序。与其他方法相比,该方法具有非破坏性和更经济的优点。在某些情况下,该方法的结果可与其他方法(如紫外线激发荧光法和透射光与斜射光照明法)的结果相辅相成,而在其他情况下,该方法则具有独特的优势。
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引用次数: 0
Two simplified tooth sample preparation methods for conventional laboratory and RapidHIT™ ID workflows 两种简化的牙齿样本制备方法,适用于传统实验室和 RapidHIT™ ID 工作流程。
IF 1.5 4区 医学 Q2 MEDICINE, LEGAL Pub Date : 2024-09-04 DOI: 10.1111/1556-4029.15624
Morgan Eaton BS, M. Shane Woolf PhD, Samyuktha Pemmasani, Triniti Turner BS, Janina Golob Deeb DMD, MS, Tracey Dawson Green PhD

Disaster victim identification (DVI) refers to the forensic identification of unknown individuals following a mass disaster event. Human dental structures can contain viable DNA sources when other soft tissues are compromised. However, labor-intensive sample preparation performed by extensively trained personnel is needed to expose the nuclear material for traditional forensic DNA workflows. With this in mind, we evaluated two simplified sample preparation protocols for processing tooth samples using either a conventional forensic DNA workflow or the Applied Biosystems® RapidHIT™ ID instrument. Briefly, sample sets for both protocols included 10 deciduous teeth that were cleaned prior to either fragmentation with a claw hammer (for RapidHIT™ ID processing) or fine-powder pulverization with a consumer-grade coffee grinder (for traditional workflows). The average percentage of expected STR alleles that were detected above analytical threshold for these tooth samples were comparable between methods: RapidHIT™ ID = 99.0% and GlobalFiler™ = 99.8%. Average intralocus heterozygote peak height ratios (PHRs) were comparable: RapidHIT™ ID = 0.80 and GlobalFiler™ = 0.86. Importantly, 9 of 10 samples analyzed via the RapidHIT™ ID required analyst review for flagged artifact peaks and quality issues. Across all profiles, 91% of alleles passed quality metrics for the RapidHIT™ workflow versus 100% for conventional GlobalFiler™ analysis. Collectively, these results suggest that quick, low-tech tooth sample fragmentation followed by analysis with the RapidHIT™ ID instrument can produce complete STR profiles from aged tooth samples. Future studies should include larger samples sets, more challenging tooth samples, and further simplification of sample preparation to enable field-forward, on-scene DVI.

灾难受害者身份鉴定(DVI)是指对大规模灾难事件后的未知人员进行法医鉴定。当其他软组织受到破坏时,人类牙齿结构中可能含有可行的 DNA 来源。然而,传统的法医 DNA 工作流程需要经过广泛培训的人员进行劳动密集型样本制备,以暴露核材料。有鉴于此,我们评估了使用传统法医 DNA 工作流程或 Applied Biosystems® RapidHIT™ ID 仪器处理牙齿样本的两种简化样本制备方案。简而言之,两种方案的样本集都包括 10 颗乳牙,在用爪锤破碎(用于 RapidHIT™ ID 处理)或用消费级咖啡研磨机细粉粉碎(用于传统工作流程)之前都要进行清洁。在这些牙齿样本中,检测到的高于分析阈值的预期 STR 等位基因的平均百分比在不同方法之间具有可比性:RapidHIT™ ID = 99.0% 和 GlobalFiler™ = 99.8%。病灶内杂合峰高比 (PHR) 平均值相当:RapidHIT™ ID = 0.80 和 GlobalFiler™ = 0.86。重要的是,在通过 RapidHIT™ ID 分析的 10 个样本中,有 9 个样本需要分析师对标记的伪峰和质量问题进行审查。在所有图谱中,RapidHIT™ 工作流程有 91% 的等位基因通过了质量指标检测,而传统 GlobalFiler™ 分析的等位基因通过率为 100%。总之,这些结果表明,快速、低技术含量的牙齿样本破碎,然后使用 RapidHIT™ ID 仪器进行分析,可以从陈旧的牙齿样本中得到完整的 STR 图谱。未来的研究应包括更大的样本集、更具挑战性的牙齿样本,并进一步简化样本制备,以实现现场直接 DVI。
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引用次数: 0
Comparison of GPR signals over simulated clandestine graves with domestic pigs (Sus Scrofa domesticus) and human remains 家猪(Sus Scrofa domesticus)和人类遗骸在模拟地下坟墓上的 GPR 信号比较。
IF 1.5 4区 医学 Q2 MEDICINE, LEGAL Pub Date : 2024-09-04 DOI: 10.1111/1556-4029.15622
Aidan Armstrong, Kennedy O. Doro PhD, Katrina Cristino, Agathe Ribéreau-Gayon PhD, Shari L. Forbes PhD, William T. D. Wadsworth MA, Carl-Georg Bank PhD

Studies assessing the use of ground-penetrating radar (GPR) for locating unmarked human graves commonly use pigs as proxies, with recent concerns about the adequacy of pigs as substitutes for humans. Also, there is little agreement on how to identify and describe GPR signals associated with graves. Hence, this project's aim is to compare GPR signals acquired over simulated clandestine graves with pig and human remains. We established human, pig, and control graves at the REST[ES] human decomposition facility in May 2022 and monitored the graves over 17 months using a 250 MHz antenna GPR system. Our results showed the presence of perturbed and V-shaped reflectors, diffraction hyperbolas, and reflectors with amplitude loss at depth between 0.6 and 0.75 m in the radargram for graves with human and pig remains. We corroborate recent studies which concluded that the use of proxies is a viable alternative to human cadavers. The observed radar signatures were classified into five key patterns, which are characteristic of similar data collected with 250 MHz above graves reported in the literature. These classes are: V-shaped dipping reflections from grave walls (class A), small hyperbolic reflections superimposed onto a near-linear reflector (class B), hyperbolic reflections from remains within the grave (class C), new high-amplitude reflection patterns (class D) and significant loss or interruption of reflections (class E). Our proposed classification can help streamline future investigations where the goal is to interpret burials within large GPR datasets and provide language to communicate these results to the broader scientific community.

评估使用探地雷达(GPR)定位无标记人类坟墓的研究通常使用猪作为替代物,但最近人们对猪是否足以替代人类表示担忧。此外,在如何识别和描述与坟墓相关的 GPR 信号方面也鲜有共识。因此,本项目的目的是比较在模拟地下坟墓上采集到的猪和人类遗骸的 GPR 信号。我们于 2022 年 5 月在 REST[ES] 人类分解设施建立了人类、猪和对照坟墓,并使用 250 MHz 天线 GPR 系统对坟墓进行了长达 17 个月的监测。我们的研究结果表明,在埋有人类和猪类遗骸的坟墓的雷达图中,存在扰动和 V 形反射体、衍射双曲线,以及深度在 0.6 至 0.75 米之间的振幅损失反射体。我们证实了近期研究的结论,即使用代用体是替代人类尸体的可行方法。观测到的雷达信号被分为五种主要模式,这些模式与文献中报道的在坟墓上方用 250 MHz 采集到的类似数据具有相同的特征。这些类别是来自墓壁的 V 形倾斜反射(A 类)、叠加在近线性反射体上的小双曲线反射(B 类)、来自墓穴内遗骸的双曲线反射(C 类)、新的高振幅反射模式(D 类)以及反射的明显损失或中断(E 类)。我们提出的分类方法有助于简化未来的调查工作,其目标是解释大型 GPR 数据集中的墓葬,并提供向更广泛的科学界传达这些结果的语言。
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引用次数: 0
Correction to: A study of DNA transfers onto plastic packets placed in personal bags 对 "关于将 DNA 转移到放在个人包中的塑料袋上的研究 "的更正。
IF 1.5 4区 医学 Q2 MEDICINE, LEGAL Pub Date : 2024-09-04 DOI: 10.1111/1556-4029.15618

Lee LYC, Lee YS, Tan J, Lee JY, Syn CK. A study of DNA transfers onto plastic packets placed in personal bags. J Forensic Sci. 2024;69(2):430–6. https://doi.org/10.1111/1556-4029.15460

In section 2.2 DNA Processing, there is a missing character ‘1’ immediately after ‘3 to’ in the text.

The current text reads: “In general, the proportion of major to minor contributors should be at least 3 to and any profile with three or more contributors at an indistinct level would be deemed not interpretable.”

The correct text should read: “In general, the proportion of major to minor contributors should be at least 3 to 1 and any profile with three or more contributors at an indistinct level would be deemed not interpretable.”

We apologize for this error.

Lee LYC, Lee YS, Tan J, Lee JY, Syn CK.DNA转移到个人包中塑料袋上的研究。J Forensic Sci. 2024;69(2):430-6。https://doi.org/10.1111/1556-4029.15460In 第 2.2 节 DNA 处理中,"3 to "后面少了一个字符 "1"。现在的内容是:"一般来说,主要贡献者与次要贡献者的比例至少应为 3 比,任何有 3 个或更多贡献者的图谱水平不明确,将被视为不可解释。"正确的文字应为:"一般来说,主要贡献者与次要贡献者的比例至少应为 3 比:"一般来说,主要撰稿人与次要撰稿人的比例应至少为 3 比 1,任何有三个或更多撰稿人的简介,其层次不明确,将被视为不可解释。"我们对这一错误表示歉意。
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引用次数: 0
Acute aconitine poisoning resulting from the ingestion of medicinal liquor 摄入药酒导致急性乌头碱中毒。
IF 1.5 4区 医学 Q2 MEDICINE, LEGAL Pub Date : 2024-09-04 DOI: 10.1111/1556-4029.15621
Ruoyu Huang MD, Qiuyu Pang MD, Lexin Zheng MD, Rui Duan BSc, Ying Wang PhD, Zhiyong Wang BSc, Tao Wang MD, PhD

Diester diterpenoid alkaloids (DDAs) are the main active ingredients of herbaceous perennial plants Aconitum. DDAs possess cardiotoxic and neurotoxic properties. Although most deaths caused by DDA poisoning are accidental, a few instances of suicide and homicide have been reported. Presented is a case of an acute aconitine (AC) poisoning following the ingestion of approximately 50 mL of homemade medicinal liquor. We described the clinical manifestations after poisoning and detailed postmortem changes, and detected the concentrations of AC and hypaconitine (HA) by liquid chromatography–tandem mass spectrometry (LC–MS/MS). The decedent experienced a burning sensation in the gastrointestinal tract after poisoning, followed by flushing and paralysis of the face and limbs, and severe cardiac arrhythmia. An autopsy revealed cyanosis of the lips and nail beds; conjunctival hemorrhage in both eyes; pulmonary edema; tissue hemorrhage and congestion in multiple organs; and inflammatory cell infiltration in the stomach, duodenum, pancreas, and cardiac muscle. The concentrations of AC and HA were as follows: cardiac blood, 38.4 ng/mL and 7.1 ng/mL; pericardial fluid, 7.3 ng/mL and 41 ng/mL; urine, 28.1 ng/mL and 574 ng/mL; bile, 38.5 ng/mL and 108 ng/mL; gastric contents, 0.06 mg and 0.56 mg; liver tissue, 10.7 ng/g and 109.6 ng/g; and medicinal liquor, 0.568 mg/mL and 0.664 mg/mL, respectively. The clinical manifestations, anatomy findings, and quantitative data on the concentrations of AC and HA in body fluids and tissues will aid forensic investigations of deaths caused by acute AC poisoning.

二酯二萜生物碱(DDAs)是多年生草本植物乌头的主要活性成分。DDAs 具有心脏毒性和神经毒性。虽然大多数 DDA 中毒导致的死亡都是意外事故,但也有少数自杀和他杀的报道。本文介绍了一例因摄入约 50 毫升自制药酒而导致急性乌头碱(AC)中毒的病例。我们描述了中毒后的临床表现和详细的尸检变化,并通过液相色谱-串联质谱法(LC-MS/MS)检测了乌头碱和次乌头碱(HA)的浓度。死者中毒后胃肠道有灼烧感,随后面部和四肢潮红、麻痹,并出现严重的心律失常。尸检结果显示:嘴唇和甲床发绀;双眼结膜出血;肺水肿;多个器官组织出血和充血;胃、十二指肠、胰腺和心肌有炎症细胞浸润。AC 和 HA 的浓度如下:心血,38.4 纳克/毫升和 7.1 纳克/毫升;心包液,7.3 纳克/毫升和 41 纳克/毫升;尿液,28.1 纳克/毫升和 574 纳克/毫升;胆汁,38.5纳克/毫升和108纳克/毫升;胃内容物,分别为0.06毫克和0.56毫克;肝组织,分别为10.7纳克/克和109.6纳克/克;药液,分别为0.568毫克/毫升和0.664毫克/毫升。临床表现、解剖结果以及体液和组织中 AC 和 HA 浓度的定量数据将有助于对急性 AC 中毒导致的死亡进行法医调查。
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Journal of forensic sciences
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