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Prognostic Significance Association of Neutrophil-To- Lymphocyte Ratio and Platelets-To-Lymphocyte Ratio with Mortality in COVID19 Patients 中性粒细胞与淋巴细胞比值、血小板与淋巴细胞比值与covid - 19患者死亡率的预后意义
Pub Date : 2021-09-05 DOI: 10.37506/IJFMT.V15I4.17354
H. Mohammed, Sama M. N. Attiyah
Background: Inflammation is a key factor in COVID-19 progression and is potentially an importantpredictive factor. The ratios of neutrophils to lymphocytes and platelets to lymphocytes may showsignificant inflammatory progression, which may contribute to the development of some majorcomplications and mortality problems as observed in COVID-19. Objective: To examine and investigatethe correlation of neutrophil lymphocytic ratio (NLR) and platelets to lymphocytes ratio (PLR) withincreased mortality risk.Methods: 124 patients admitted to King Abdulaziz hospital with confirmed COVID-19 were enrolled inour study. The blood cell count was used to obtain NLR and PLR. The receiver operating characteristic(ROC) curve was used to determine the sensitivity and specificity of NLR and PLR for severity andmortality of admitted patients with COVID-19. The logistic regression model was used to explore therisk factors associated with mortality and severity.Results: The mortality rate was 23.4%. Among non-survivors’ patients’ lymphocyte significantlydeclined with 96.5%, while neutrophil counts increased. The Empirical optimal cut point of NLRcorrelated with mortality is 4.647, with a sensitivity of 93% and a specificity of 61% (AUC: 0.847, 95%CI 0.774-0.921; P = 0.001). Moreover, the optimal cut point of PLR associated mortality is 17.358,with a sensitivity of 90% and a specificity of 64% (AUC: 0.791, 95% CI 0.703-0.878; P = 0.005).Conclusions: NLR and PLR variables were significantly correlated with severity and mortality. NLRand PLR can be considered independent biomarkers in COVID-19 patients which play a significant roleto predict mortality cases.
背景:炎症是COVID-19进展的关键因素,也是潜在的重要预测因素。中性粒细胞与淋巴细胞和血小板与淋巴细胞的比例可能显示出明显的炎症进展,这可能导致一些主要并发症的发生和COVID-19中观察到的死亡率问题。目的:探讨中性粒细胞淋巴细胞比(NLR)和血小板淋巴细胞比(PLR)与死亡风险增加的相关性。方法:选取124例在阿卜杜勒阿齐兹国王医院确诊的COVID-19患者作为研究对象。用血细胞计数计算NLR和PLR。采用受试者工作特征(ROC)曲线确定NLR和PLR对入院患者COVID-19严重程度和死亡率的敏感性和特异性。采用logistic回归模型探讨与死亡率和严重程度相关的危险因素。结果:死亡率为23.4%。在非幸存者患者中,淋巴细胞明显下降,为96.5%,而中性粒细胞计数增加。nlr与死亡率相关的经验最佳切点为4.647,敏感性为93%,特异性为61% (AUC: 0.847, 95%CI 0.774 ~ 0.921;P = 0.001)。此外,PLR相关死亡率的最佳切点为17.358,敏感性为90%,特异性为64% (AUC: 0.791, 95% CI 0.703-0.878;P = 0.005)。结论:NLR和PLR变量与严重程度和死亡率显著相关。nlr和PLR可被认为是COVID-19患者的独立生物标志物,在预测死亡率病例中发挥重要作用。
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引用次数: 0
Febrile Seizures in Thalassemic Patients in Babylon Teaching Hospital for Maternity and Children 巴比伦妇幼教学医院地中海贫血患者的热性惊厥
Pub Date : 2021-09-05 DOI: 10.37506/IJFMT.V15I4.17233
Yahya A. Altufaily, Hakim Yosif Radhi, Laith Jasim khejani
Febrile seizures are the most common seizures in children. Their incidence is (2-5 %). To date, thepathophysiology of febrile seizures is unknown. But several hypotheses have been supposed that itmay relate with plasma iron level. Such low risk in thalassemic patients whose plasma iron level is highcould give some clues to this hypothesis.Aim of the Study: Determine the risk of febrile seizure in thalassemic patients in comparism with thecorresponding control group.Patients and Methods: This case –control study was conducted on one hundred fifty patients withthalassemia major between six month and six years of age who were visit Babylon center for inheritedblood diseases in the Teaching hospital for maternity and children from April 2019 to January 2020.All medical records of thalassemic patients were thoroughly reviewed and the occurrence of febrileseizures are interviewed and compared with the control group .The children in the control group areneither thalassemic nor has iron deficiency anemia.Results: Febrile seizure was detected in one case of the thalassemic group (0.66%) versus six cases(4%) of the control group. The risk of febrile seizure in the control group was 6 times more than that inthe thalassemia group, which was statistically significant (P =0.036).Conclusion: The risk of febrile seizures in thalassemic patients was (0.16) that of the general childrenpopulation. Thus, iron overload may be a major factor involving the brain metabolism that preventsfebrile seizures.
热性惊厥是儿童最常见的惊厥。其发生率为(2- 5%)。迄今为止,热性惊厥的病理生理学尚不清楚。但有几种假说认为它可能与等离子体铁水平有关。血浆铁含量高的地中海贫血患者的这种低风险可能为这一假设提供一些线索。研究目的:确定地中海贫血患者与相应对照组的热性癫痫发作风险。患者与方法:对2019年4月至2020年1月在妇幼教学医院巴比伦遗传血液病中心就诊的150例6个月至6岁的地中海贫血患者进行病例对照研究。对所有地中海贫血患者的医疗记录进行全面回顾,并与对照组进行热性惊厥的访谈和比较。对照组患儿既没有地中海贫血,也没有缺铁性贫血。结果:地中海贫血组发热性惊厥1例(0.66%),对照组6例(4%)。对照组发生热性惊厥的风险是地中海贫血组的6倍,差异有统计学意义(P =0.036)。结论:地中海贫血患者发生热性惊厥的风险是普通儿童的0.16。因此,铁超载可能是一个主要因素,涉及大脑代谢,防止发热性癫痫发作。
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引用次数: 0
Effect of Clinical Guideline Concerning Cardiopulmonary Bypass on Nurses’ Knowledge in Open Heart Surgery Center. 体外循环临床指南对心内直视手术中心护士知识的影响。
Pub Date : 2021-09-05 DOI: 10.37506/IJFMT.V15I4.17249
Mustafa Majeed, R. Hamza
Open-heart surgery is considered a major surgery with potential risks and complications, but it is a lifesavingoperation that can treat a variety of diseases such as heart valve disease, heart birth defects, andcoronary artery disease. A Quasi- experimental design has been used in the existing study to evaluatethe effect of clinical guideline concerning cardiopulmonary bypass on nurses’ knowledge in open heartsurgery center in AL-Najaf AL-Ashraf city at Al-Najaf center for cardiac surgery and trans-cathetertherapy through the period October 1th, 2020 to, April 19th , 2021. The results of the study show there isa high significant effect of the educational program, it also, show that high Significant mean differenceamong study group concerning pre-test and post-test scores at p-value (0.0001). Also, in this study thereis a significant association between posttest knowledge and year of experience as a perfusionists andnumber of training courses at p-value (0.02) and (0.01).The study concluded that educational programcan improve in nurses’ knowledge and to produce perfusionists who are able to successfully apply theirknowledge and skills to improve patients’ outcome. The study recommended a written program forall new nurses working in heart-lung machine department, and improving the expertise of nurses andmedical staff through use the finding of the present study to give care for the patient.
心内直视手术被认为是一项有潜在风险和并发症的大手术,但它是一项挽救生命的手术,可以治疗各种疾病,如心脏瓣膜疾病、心脏先天缺陷和冠状动脉疾病。本研究采用准实验设计,评估2020年10月1日至2021年4月19日期间,AL-Najaf AL-Ashraf市心脏直视手术中心心脏手术及经导管治疗临床指南对AL-Najaf中心护士体外循环知识的影响。研究结果表明,教育计划有很高的显著性效果,也表明,研究组之间关于测试前和测试后分数的p值(0.0001)有很高的显著性平均差异。此外,在本研究中,测试后知识与灌注师经验年和培训课程数量之间存在显著的关联,p值为(0.02)和(0.01)。研究结果表明,教育计划可以提高护士的知识水平,培养出能够成功运用知识和技能改善患者预后的灌注师。本研究建议所有在心肺机科工作的新护士都有一个书面的程序,并通过本研究的发现来提高护士和医务人员的专业知识,以照顾病人。
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引用次数: 0
Effect of Sperm Morphology on Normal Pregnancy 精子形态对正常妊娠的影响
Pub Date : 2021-09-05 DOI: 10.37506/IJFMT.V15I4.17258
Samraà Maki Hamed, Yusra Salih Khudair
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引用次数: 0
Detection the Level of Anxiety and Depression among Diabetic Foot Patients at Al-Najaf Al-Ashraf Teching Hospitals Al-Najaf Al-Ashraf教学医院糖尿病足患者焦虑和抑郁水平的检测
Pub Date : 2021-09-05 DOI: 10.37506/IJFMT.V15I4.17261
A. D. Salman, S. Bakey
Objective: The study was done to assess the level of anxiety and depression among diabetic foot patientsat Al-Najaf Al-Ashraf Teaching Hospitals. Also to find out relationships between anxiety and depressionof diabetic foot patients and their demographic characteristics. Methodology: a descriptive correlationaldesign, the study established for a period from 10th October, 2020 to 1st June, 2021. The study was conductedon a probability (accidental) sample of 120 patients who have a diabetic foot which was selected from Al-Sadder teaching hospital and Al-Furat teaching hospital in Al-Najaf Al-Ashraf Governorate. The researcheris using the Hospital Anxiety and Depression Scale to assess the level of anxiety and depression. Results:The result of the study showed (37.5%) of the study sample had moderate anxiety. Furthermore, the studyshows (36.6%) of the study participant have moderate depression. Contingency correlation analysis showedthat anxiety and depression is a significant correlation with the number of hospital admission, duration ofcurrent admission, and previous amputation. In addition, anxiety was significantly correlated with gender,educational level, duration of the diabetic foot. Besides, depression was significantly correlated with age,economic status, having other chronic diseases.
目的:研究Al-Najaf Al-Ashraf教学医院糖尿病足患者的焦虑和抑郁水平。探讨糖尿病足患者焦虑、抑郁与人口学特征的关系。研究方法:采用描述性相关设计,研究时间为2020年10月10日至2021年6月1日。本研究选取了纳杰夫阿什拉夫省Al-Sadder教学医院和Al-Furat教学医院的120名糖尿病足患者作为概率(偶然)样本。研究人员采用医院焦虑抑郁量表评估患者的焦虑抑郁水平。结果:研究结果显示,37.5%的研究样本有中度焦虑。此外,研究显示(36.6%)的研究参与者患有中度抑郁症。权变相关分析显示,焦虑、抑郁与住院次数、住院时间、截肢史有显著相关。此外,焦虑与性别、文化程度、糖尿病足病程显著相关。此外,抑郁症与年龄、经济状况、患有其他慢性疾病显著相关。
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引用次数: 0
Effectiveness of an Instructional Program on Gastric Carcinoma Patients Knowledge Undergoing Chemotherapy toward Self Care after Gastrectomy at Oncology Unit of ALHaboby Teaching Hospital in AL-Naseria City 在AL-Naseria市ALHaboby教学医院肿瘤科开展胃癌患者胃切除术后化疗自我护理知识指导项目的效果
Pub Date : 2021-09-05 DOI: 10.37506/IJFMT.V15I4.17255
H. Jabbar, S. J. Muhamad
Aims: To determine the effectiveness of instructional program on self-care knowledge patientsundergoing chemotherapy after gastrectomy. Methods: Pre-experimental pre-post test design wasconducted in Al-Naseria City. The data collection process uses the interview technique and analyzedthrough the descriptive statistic. Results: There is statistically significance differences between preposttest knowledge, which mean effectiveness of instructional program knowledge of self care aftergastrectomy. Conclusion: In the post-test, there was a big difference in the patients’ knowledge leveltowards self-care. Establishing specialized centers to educate patients importance of early detection ofcancer.
目的:探讨胃切除术后化疗患者自我护理知识教学方案的有效性。方法:在Al-Naseria市进行实验前、实验后试验设计。数据收集过程采用访谈法,并通过描述性统计进行分析。结果:胃切除术后自我护理教学方案知识与前测后知识差异有统计学意义。结论:在后测中,患者的自我保健知识水平存在较大差异。建立专门的中心,教育患者早期发现癌症的重要性。
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引用次数: 0
Evaluation of the Social Wellbeing Status and Associated factors in Students of Dezful University of Medical Sciences (Iran): A Cross-sectional Study 伊朗Dezful医科大学学生社会福利状况及相关因素评价:横断面研究
Pub Date : 2021-08-16 DOI: 10.37506/IJFMT.V15I4.17183
Fereshteh Sohrabivafa, K. Azam, Malihe Sohrabivafa
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引用次数: 0
An Analysis of the Implementation of Diversion in Efforts to Settle Medical Disputes in Indonesia 印尼医疗纠纷解决中分流的实施分析
Pub Date : 2021-08-16 DOI: 10.37506/IJFMT.V15I4.17180
Arista Candra Irawati, S. Putra, R. M. Sukmariningsih, Adhi Putra Satria
Based on the legal construction contained in Article 29 of Law Number 36 the Year 2009 concerning Health,it has ordered that health workers suspected of neglecting in carrying out their profession. There is a needfor a settlement preceded by the mediation stage or what is known as the settlement of disputes out of thecourt. The facts in the field show that the handling of medical disputes, especially for doctors who commitnegligence, has not been fully implemented according to the provisions of Article 29 of the Health Law,meaning that the handling is not carried out through the first mediation stage, as in the case experienced bydr. Ayu et al. They had to be brought to court accused of committing medical malpractice because they failedto save the patient during a cito-cesarean operation. Dr. Ayu et al. at that time did not fulfill their rights to getmediation. This is because there has been no further regulation governing the procedures, procedures, andrules for implementing mediation, especially health services. Due to this fact, it becomes an obstacle to theconsistency of mediation efforts as a necessity in solving medical disputes. Law No. 29 of 2004 concerningMedical Practice and Regulation of the Medical Council Number 32 of 2015 concerning procedures forhandling suspected disciplinary violations of Doctors and Dentists do not regulate mediation efforts, so theimplementation of mediation efforts in health services is not optimal.
根据2009年关于保健的第36号法律第29条所载的法律规定,委员会下令对涉嫌玩忽职守的保健工作人员进行处罚。有必要在调解阶段或所谓的庭外解决争端之前达成和解。现场的事实表明,医疗纠纷的处理,特别是对有过失的医生的处理,并没有完全按照《卫生法》第二十九条的规定执行,这意味着处理没有像医生所经历的那样通过第一调解阶段进行。Ayu等人。他们被控医疗事故,因为他们在剖腹产手术中没能救下病人。Ayu博士等人当时没有履行他们获得调解的权利。这是因为没有进一步的条例来管理实施调解的程序、程序和规则,特别是保健服务。由于这一事实,它成为调解工作作为解决医疗纠纷的必要条件的一致性的障碍。2004年第29号法律(关于医疗实践和医疗管理)和2015年第32号法律(关于处理医生和牙医涉嫌违纪行为的程序)没有规定调解工作,因此在卫生服务中实施调解工作并不理想。
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引用次数: 0
Abuse of Topical Glucocorticoids among Patients Visiting Community Pharmacy in Basrah-Iraq 伊拉克巴士拉地区社区药房患者局部糖皮质激素滥用情况
Pub Date : 2021-08-16 DOI: 10.37506/IJFMT.V15I4.16775
Alhassan Shaker Abed, Jubran K Hassan
Introduction: Topical glucocorticoids have been the mainstay for the treatment of many skin conditions sincetheir introduction due to their anti-inflammatory, anti-proliferative vasoconstrictive and immunosuppressiveproperties.Availability of topical glucocorticoids in different potencies as over the counter medication inIraq encourages their use for non-labeled indications , thus increasing the side effect of such drugs.Objectives: The aim of this study was toevaluate the use, knowledge of the patients and patient educationoftopical glucocorticoids.Methodology: A cross sectional community pharmacy based survey was conducted throughout Basrahcity.Inclusion criteria were costumers visiting the community pharmacies asking for topical corticosteroidswithout prescription, aging 15 years and older and willing to participate in the study.600 questionnaireformafor topical corticosteroids were distributed in the center and the districts of Basrah city. 254 forma outof 600 were returned out of which 212 were completed. Incomplete forma were excluded.Result: 106 (50%) participants out of 212misused topical glucocorticoids. As a single product, Betamethasonevalerate and Clobetasol propionate was majorly used by the participants which are potent and ultra-highpotent topical steroid respectively. The major source of topical steroid prescription was relatives.49.8%participants didn’t recognize any side effect of topical glucocorticoids while hypopigmentation was themost side effect identified by the participants (21.8%).Only 35% of the participants,whom topical steroidprescription source by physicians and pharmacists, was educated about the use of topical glucocorticoids.Conclusion: Topical glucocorticoids are commonly abused in Basrah city and probably other cities of Iraq.Looking fair and improving face appearance is a common cultural believe in Iraq that push people to seektopical glucocorticoids from community pharmacies for skin lightening in addition to other unapprovedindications without prescription.
自糖皮质激素问世以来,由于其抗炎、抗增殖、血管收缩和免疫抑制的特性,局部糖皮质激素一直是治疗许多皮肤疾病的主要药物。在伊拉克,不同效价的外用糖皮质激素作为非处方药物,鼓励将其用于无标签适应症,从而增加了这类药物的副作用。目的:本研究的目的是评估局部糖皮质激素的使用,患者的知识和患者教育。方法:在整个巴士拉市进行了一项基于社区药房的横断面调查。纳入标准为:年龄在15岁及以上且愿意参加研究的到社区药店购买非处方外用皮质类固醇的顾客。在巴士拉市中心和各区发放了600份外用皮质类固醇问卷。600份表格中有254份已归还,其中212份已完成。不完整的表格被排除在外。结果:212名参与者中有106名(50%)滥用局部糖皮质激素。作为单一产品,参与者主要使用倍他米松evalerate和丙酸氯倍他索,它们分别是强效和超高效的外用类固醇。外用类固醇处方的主要来源是亲属,49.8%的参与者没有意识到外用糖皮质激素的任何副作用,而色素沉着是参与者发现的最多的副作用(21.8%)。只有35%的参与者接受过关于糖皮质激素使用的教育,这些参与者是由医生和药剂师提供局部类固醇处方的。结论:局部糖皮质激素在巴士拉市和伊拉克其他城市普遍滥用。在伊拉克,美白和改善面容是一种普遍的文化信仰,这促使人们从社区药房寻求局部糖皮质激素来美白皮肤,此外还有其他未经批准的无处方药物。
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引用次数: 1
Study of Various Patterns of Azygos Venous System and its Clinical Significance 奇静脉系统各种形态的研究及其临床意义
Pub Date : 2021-08-16 DOI: 10.37506/IJFMT.V15I4.16650
A. Rohilla, M. Rathee, K. Singh, S. Rathee
Background: The azygos system includes those veins which are straight in course, paravertebral in positionand not accompanied with the corresponding arteries. The azygos vein may arise as lumbar azygos veinfrom the back of inferior vena cava or by the union of right subcostal and right ascending lumbar veins. Itenters the thorax, receives lower 8 right posterior intercostal veins, superior intercostal vein, hemiazygosand accessory hemiazygos veins and ends by joining the superior vena cava. The hemiazygos vein is formedon the left in a manner similar to that of azygos vein. The aim of the present study was to investigate thevarious patterns of the azygos venous system.Methods: A total number of 30 cadavers were studied and were evaluated based on the study of Anson BJand Mcvay CB.Conclusion: Out of 30 specimens studied, 17 (56%) specimens showed normal pattern, 5 (16%) specimensshowed caterpillar pattern and rest 8 (26%) specimens showed ladder pattern.Azygos system of veins serve as an alternative drainage channel between superior vena cava and inferiorvena cava in case of obstruction. The knowledge of various patterns could be useful for radiologists andsurgeons to prevent intra-operative hazards.
背景:奇静脉系统包括那些在路线上是直的,在位置上是椎旁的,不伴有相应的动脉的静脉。奇静脉可以起源于下腔静脉的后部,也可以由右肋下静脉和右上升腰静脉结合而成。进入胸腔,接受右下8后肋间静脉,上肋间静脉,半斜静脉和副半斜静脉,最后与上腔静脉相连。半奇静脉在左侧以类似奇静脉的方式形成。本研究的目的是探讨奇静脉系统的各种模式。方法:对30具尸体进行研究,并以Anson BJand Mcvay CB为基础进行评价。结论:30例标本中,正常形态17例(56%),毛虫形态5例(16%),阶梯形态8例(26%)。奇静脉系统作为上腔静脉和下腔静脉之间的备用引流通道,以防阻塞。各种模式的知识对放射科医生和外科医生预防术中危害是有用的。
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引用次数: 0
期刊
Journal of Forensic Medicine
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