Pub Date : 2021-08-16DOI: 10.37506/IJFMT.V15I4.17179
Abbas Abdulmueed Mustafa Alani, Ihab Q. Ali, Yasir Khaleel Almusawi
The silent killer or ovarian cancer (OC) is one of the major causes of cancer deaths among women in themodern age. In view of the therapeutic roles of platinum based chemotherapy among the ovarian cancerpatients, objective of this report was to assess the effects of the first round of chemotherapy among womenwith ovarian cancer. Here, the levels of the pleural markers for cancer bio markers, before and after thechemotherapy were tested among ovarian cancer patients. The biochemical indices may be of use indeciphering the relation between cancer relapse and platinum retrieval. The pleural analyses pre and postplatinum chemotherapy session demonstrated wide range of biochemical and protein marker changes amongovarian cancer patients. The various cancer antigens were variedly reduced post chemotherapy. Hence, it isproposed that biochemical markers in pleural liquid may serve as better indicators and early diagnostic toolsfor ovarian cancer.
{"title":"Changes in the Cancer Antigen Markers in the Pleural Liquid During Chemotherapy among Ovarian Cancer Patients","authors":"Abbas Abdulmueed Mustafa Alani, Ihab Q. Ali, Yasir Khaleel Almusawi","doi":"10.37506/IJFMT.V15I4.17179","DOIUrl":"https://doi.org/10.37506/IJFMT.V15I4.17179","url":null,"abstract":"The silent killer or ovarian cancer (OC) is one of the major causes of cancer deaths among women in themodern age. In view of the therapeutic roles of platinum based chemotherapy among the ovarian cancerpatients, objective of this report was to assess the effects of the first round of chemotherapy among womenwith ovarian cancer. Here, the levels of the pleural markers for cancer bio markers, before and after thechemotherapy were tested among ovarian cancer patients. The biochemical indices may be of use indeciphering the relation between cancer relapse and platinum retrieval. The pleural analyses pre and postplatinum chemotherapy session demonstrated wide range of biochemical and protein marker changes amongovarian cancer patients. The various cancer antigens were variedly reduced post chemotherapy. Hence, it isproposed that biochemical markers in pleural liquid may serve as better indicators and early diagnostic toolsfor ovarian cancer.","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"os-26 1","pages":"2978-2983"},"PeriodicalIF":0.0,"publicationDate":"2021-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87404814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-10DOI: 10.4038/SLJFMSL.V3I2.4474
Luv Sharma
An honor killing (in Hindi this term can be translated as “Samman Hatya”) is the murder of a female family or clan member by one or more fellow family members, where the murderers and potentially the wider community believe the victim to have brought dishonor upon the family, clan, or community. This perceived dishonor is normally the result of (a) utilizing dress codes unacceptable to the family (b) wanting out of an arranged marriage or choosing to marry by own choice, (c) engaging in certain sexual acts or (d) engaging in relations with the same sex. These killings result from the perception that defense of honor justifies killing a person whose behavior dishonors their clan or family [1]. Honor killings have been reported from antiquity from all over the world, however the recent past has shown an alarming and disturbing resurgence of this inhuman deed. This paper presents two homicide cases related to honour killing: a dual homicide of two lovers who were killed in the name of preserving family honor and hanged after death together by the entire village. The pattern of injuries in both cases and crime scene are discussed in detail.
{"title":"HONOUR KILLING- A CASE REPORT","authors":"Luv Sharma","doi":"10.4038/SLJFMSL.V3I2.4474","DOIUrl":"https://doi.org/10.4038/SLJFMSL.V3I2.4474","url":null,"abstract":"An honor killing (in Hindi this term can be translated as “Samman Hatya”) is the murder of a female family or clan member by one or more fellow family members, where the murderers and potentially the wider community believe the victim to have brought dishonor upon the family, clan, or community. This perceived dishonor is normally the result of (a) utilizing dress codes unacceptable to the family (b) wanting out of an arranged marriage or choosing to marry by own choice, (c) engaging in certain sexual acts or (d) engaging in relations with the same sex. These killings result from the perception that defense of honor justifies killing a person whose behavior dishonors their clan or family [1]. Honor killings have been reported from antiquity from all over the world, however the recent past has shown an alarming and disturbing resurgence of this inhuman deed. This paper presents two homicide cases related to honour killing: a dual homicide of two lovers who were killed in the name of preserving family honor and hanged after death together by the entire village. The pattern of injuries in both cases and crime scene are discussed in detail.","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85413095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-02DOI: 10.37506/IJFMT.V15I3.16257
B. Skal, S. Ahmed
{"title":"Effectiveness of an Educational Program on Nurses’ knowledge about Risk Factors for Bleeding of Acute Myocardial Infarction in Patient Receiving Thrombolytic Therapy at Coronary Care Unit in Al-Diwaniya Teaching Hospital","authors":"B. Skal, S. Ahmed","doi":"10.37506/IJFMT.V15I3.16257","DOIUrl":"https://doi.org/10.37506/IJFMT.V15I3.16257","url":null,"abstract":"","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"56 1","pages":"5183-5190"},"PeriodicalIF":0.0,"publicationDate":"2021-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84880611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-25DOI: 10.4038/SLJFMSL.V12I1.7854
S. Gunawardena, J. Weeratna
Identifying a perpetrator by bite mark analysis is generally based on the detection of tooth impressions that correspond to unique and rare odontological traits. A 34-year-old female presented with a history of assault where she also claimed that the assailant bit her during the struggle. There was a well defined bite mark on her left forearm along with blunt force injuries on the head. During forensic odontological examination, the wax bite registration of the victim showed several common dental irregularities which were also represented in the bite mark. The location and orientation of the injury also favoured the possibility of self-infliction and no inconsistencies could be found to exclude this bite mark as a fabricated injury in the setting of an assault. The lack of population specific studies and objective methods of analysis are significant limitations in bite mark analysis. When providing opinion on the identity of the biter, the general recommendation is to use unique features or uncommon irregularities. However, even where only common dental irregularities are seen, a reasonably valid opinion could still be provided using a holistic and deductive approach, if there is sufficient concordance among multiple irregularities with no inconsistencies.
{"title":"Fabricated bite mark in a case of assault","authors":"S. Gunawardena, J. Weeratna","doi":"10.4038/SLJFMSL.V12I1.7854","DOIUrl":"https://doi.org/10.4038/SLJFMSL.V12I1.7854","url":null,"abstract":"Identifying a perpetrator by bite mark analysis is generally based on the detection of tooth impressions that correspond to unique and rare odontological traits. A 34-year-old female presented with a history of assault where she also claimed that the assailant bit her during the struggle. There was a well defined bite mark on her left forearm along with blunt force injuries on the head. During forensic odontological examination, the wax bite registration of the victim showed several common dental irregularities which were also represented in the bite mark. The location and orientation of the injury also favoured the possibility of self-infliction and no inconsistencies could be found to exclude this bite mark as a fabricated injury in the setting of an assault. The lack of population specific studies and objective methods of analysis are significant limitations in bite mark analysis. When providing opinion on the identity of the biter, the general recommendation is to use unique features or uncommon irregularities. However, even where only common dental irregularities are seen, a reasonably valid opinion could still be provided using a holistic and deductive approach, if there is sufficient concordance among multiple irregularities with no inconsistencies.","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"66 1","pages":"24"},"PeriodicalIF":0.0,"publicationDate":"2021-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80415015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-25DOI: 10.4038/SLJFMSL.V12I1.7855
A. Goethem, H. Neels, A. V. Hoyweghen, W. Jacobs
“Marijuana lung” refers to a radiological-pathological entity of apical (bullous) paraseptal emphysema in persons who regularly smoke cannabis. We describe a post-mortem case of a drowned young man in whom apical bullous emphysema was seen on post-mortem computed tomography (PMCT) as an incidental finding. Histopathology confirmed the existence of apical paraseptal emphysema. Toxicology, including hair analysis, confirmed that he was a chronic cannabis user. As such this case report can be supportive of the association between chronic cannabis use and the development of paraseptal emphysema.
{"title":"Marijuana lung: radiological, macroscopic and histopathological triptych","authors":"A. Goethem, H. Neels, A. V. Hoyweghen, W. Jacobs","doi":"10.4038/SLJFMSL.V12I1.7855","DOIUrl":"https://doi.org/10.4038/SLJFMSL.V12I1.7855","url":null,"abstract":"“Marijuana lung” refers to a radiological-pathological entity of apical (bullous) paraseptal emphysema in persons who regularly smoke cannabis. We describe a post-mortem case of a drowned young man in whom apical bullous emphysema was seen on post-mortem computed tomography (PMCT) as an incidental finding. Histopathology confirmed the existence of apical paraseptal emphysema. Toxicology, including hair analysis, confirmed that he was a chronic cannabis user. As such this case report can be supportive of the association between chronic cannabis use and the development of paraseptal emphysema.","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"2 1","pages":"29"},"PeriodicalIF":0.0,"publicationDate":"2021-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74972040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-17DOI: 10.37506/IJFMT.V15I3.15393
A. Sami
The attention has been increased to assess the hematological toxic effects of petroleum products from refineries especially the volatile chemical contaminants (VCC) like benzene. Petrol pump operators are workers frequently exposed to petroleum products that has been occasionally associated with large incidences of hematological disorders and adverse health effects as a result of damage to the haemopoietic system accompanied by depletion to the bone marrow. This study was made to evaluate the hematological parameters among petrol refinery workers according to the duration of exposure. A cross sectional study was done in Al Najaf -refinery for petrol. It involved 101 petrol pump operators, thirty one (31) healthy male office workers who were considered as the control group and two groups of seventy (70) male petrol pump operators as the study group. The samples of blood were collected from both study and control groups and tested for red blood cells count (RBC), hemoglobin concentration (Hb), white blood cell count (WBC), packed cell volume (PCV) level and platelet count (Plt). Chronic exposure to volatile chemical contaminants has a harmful effects on refinery workers with increasing the risk of developing hematological disorders due to the deleterious effects on the bone marrow
{"title":"Assessment Changes in Hematological Parameters for Iraqi Individuals That are Working in Petrol Refineries","authors":"A. Sami","doi":"10.37506/IJFMT.V15I3.15393","DOIUrl":"https://doi.org/10.37506/IJFMT.V15I3.15393","url":null,"abstract":"The attention has been increased to assess the hematological toxic effects of petroleum products from refineries especially the volatile chemical contaminants (VCC) like benzene. Petrol pump operators are workers frequently exposed to petroleum products that has been occasionally associated with large incidences of hematological disorders and adverse health effects as a result of damage to the haemopoietic system accompanied by depletion to the bone marrow. This study was made to evaluate the hematological parameters among petrol refinery workers according to the duration of exposure. A cross sectional study was done in Al Najaf -refinery for petrol. It involved 101 petrol pump operators, thirty one (31) healthy male office workers who were considered as the control group and two groups of seventy (70) male petrol pump operators as the study group. The samples of blood were collected from both study and control groups and tested for red blood cells count (RBC), hemoglobin concentration (Hb), white blood cell count (WBC), packed cell volume (PCV) level and platelet count (Plt). Chronic exposure to volatile chemical contaminants has a harmful effects on refinery workers with increasing the risk of developing hematological disorders due to the deleterious effects on the bone marrow","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"25 1","pages":"695-700"},"PeriodicalIF":0.0,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74867699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-17DOI: 10.37506/IJFMT.V15I3.15390
S. Sindhuja, Bagavad Gita
Electrosurgery is an application of electrically generated heat energy to tissue to alter it for therapeutic purposes. Electrosurgery has been used in dentistry for many purposes such as for, gingivectomy, pulpotomy, frenectomy, operculectomy and hemostasis. The main advantage of the electrocautery is coagulative effect that provide bloodless area and clear view of the operative field. With any device that creates thermal energy to cut or ablate tissue, heat may be dissipated by diffusion into adjacent tissues (conduction), or into the circulating blood.(convection) This paper highlights its application and usage in dentistry.
{"title":"Operculectomy Using Electrocautery-A Case Report","authors":"S. Sindhuja, Bagavad Gita","doi":"10.37506/IJFMT.V15I3.15390","DOIUrl":"https://doi.org/10.37506/IJFMT.V15I3.15390","url":null,"abstract":"Electrosurgery is an application of electrically generated heat energy to tissue to alter it for therapeutic purposes. Electrosurgery has been used in dentistry for many purposes such as for, gingivectomy, pulpotomy, frenectomy, operculectomy and hemostasis. The main advantage of the electrocautery is coagulative effect that provide bloodless area and clear view of the operative field. With any device that creates thermal energy to cut or ablate tissue, heat may be dissipated by diffusion into adjacent tissues (conduction), or into the circulating blood.(convection) This paper highlights its application and usage in dentistry.","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"170 1","pages":"682-684"},"PeriodicalIF":0.0,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73195964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-17DOI: 10.37506/IJFMT.V15I3.15755
Firas Shawqi Algburi, Nadia Y Al-Tikrity, H. Ulusal, T. Taşkın-Tok, Omeed Akbar Ali
The research includes the partial purification of dipeptidyl peptidase-4(Dpp-4) from a person’s natural serum.The enzyme was purified in three steps, precipitation by ammonium sulfate (50%), dialysis and gel filtration by Sephadex G-100. The results showed a significant increase of Dpp-4 activity and specific activity,and a decrease in total activity after purification.The descent of the purified enzyme with the highest activity from the separation column was identical to the descending of the protein with the highest activity. The inhibitory activity of nitrile derivatives that were used on the purified enzyme was studied. Nitrile derivatives were used to inhibit the activity of the Dpp-4, selected based on similarity in sites of effective groups between derivatives and anti-hyperglycemic drugs (Dpp-4 inhibitors type). The results show an inhibitory effect by the two nitrile derivatives with different concentrations.These inhibitors can work to reduce the level of blood sugar in people with diabetes. Moreover,Molecular docking was exerted to understand interaction mechanism of the compounds against Dpp-4 at atomic level based on experimental processes.
{"title":"Partial Purification of Dipeptidyl Peptidase-4 From Human Blood Serum and Study the Inhibitory Effect of Some Nitrile Derivatives on it","authors":"Firas Shawqi Algburi, Nadia Y Al-Tikrity, H. Ulusal, T. Taşkın-Tok, Omeed Akbar Ali","doi":"10.37506/IJFMT.V15I3.15755","DOIUrl":"https://doi.org/10.37506/IJFMT.V15I3.15755","url":null,"abstract":"The research includes the partial purification of dipeptidyl peptidase-4(Dpp-4) from a person’s natural serum.The enzyme was purified in three steps, precipitation by ammonium sulfate (50%), dialysis and gel filtration by Sephadex G-100. The results showed a significant increase of Dpp-4 activity and specific activity,and a decrease in total activity after purification.The descent of the purified enzyme with the highest activity from the separation column was identical to the descending of the protein with the highest activity. The inhibitory activity of nitrile derivatives that were used on the purified enzyme was studied. Nitrile derivatives were used to inhibit the activity of the Dpp-4, selected based on similarity in sites of effective groups between derivatives and anti-hyperglycemic drugs (Dpp-4 inhibitors type). The results show an inhibitory effect by the two nitrile derivatives with different concentrations.These inhibitors can work to reduce the level of blood sugar in people with diabetes. Moreover,Molecular docking was exerted to understand interaction mechanism of the compounds against Dpp-4 at atomic level based on experimental processes.","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"33 22","pages":"2969-2976"},"PeriodicalIF":0.0,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72470826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-17DOI: 10.37506/IJFMT.V15I3.15262
V. Jayashankar, R. Chaitanya, G. Kumar
Aim: To do a research study on Medicolegal Autopsies conducted at Government Medical College Mortuary, Ongole, Andhra Pradesh from 1st January 2020 to 31st December 2020. Materials & Methodology: This study was conducted at Government Medical College, Ongole from 1st January to 31st December 2020. A total of 534 medicolegal cases were brought to mortuary for the sake of medicolegal autopsy during the study period. Result: In the research study, it is evident from the statistics that maximum number of medicolegal autopsies were conducted in the decreasing order in the following deaths - Road Traffic Accidents < Poisoning < Hanging < Homicidal Deaths < Deaths due to hit by Train < Drowning < Burns < Fall from Height < Snake Bite. Medicolegal autopsies were done more in males compared to females in almost all types of deaths. Likewise maximum number of autopsies were conducted in the active age group of 18 to 36 years
{"title":"A Research Study on Medicolegal Autopsies Conducted at Mortuary of Government Medical College, Ongole, Andhra Pradesh from 1St January to 31St December 2020","authors":"V. Jayashankar, R. Chaitanya, G. Kumar","doi":"10.37506/IJFMT.V15I3.15262","DOIUrl":"https://doi.org/10.37506/IJFMT.V15I3.15262","url":null,"abstract":"Aim: To do a research study on Medicolegal Autopsies conducted at Government Medical College Mortuary, Ongole, Andhra Pradesh from 1st January 2020 to 31st December 2020. Materials & Methodology: This study was conducted at Government Medical College, Ongole from 1st January to 31st December 2020. A total of 534 medicolegal cases were brought to mortuary for the sake of medicolegal autopsy during the study period. Result: In the research study, it is evident from the statistics that maximum number of medicolegal autopsies were conducted in the decreasing order in the following deaths - Road Traffic Accidents < Poisoning < Hanging < Homicidal Deaths < Deaths due to hit by Train < Drowning < Burns < Fall from Height < Snake Bite. Medicolegal autopsies were done more in males compared to females in almost all types of deaths. Likewise maximum number of autopsies were conducted in the active age group of 18 to 36 years","PeriodicalId":15899,"journal":{"name":"Journal of Forensic Medicine","volume":"124 1","pages":"582-585"},"PeriodicalIF":0.0,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77344997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-17DOI: 10.37506/IJFMT.V15I3.15404
M. Mahmood, Alaa Mohammed Ali Al Baazi, Athir Ahmed Kadium
A prospective study of 20 patients with clinical diagnosis of duodenal obstruction done at pediatric surgery center in AL Khanssa maternity and children Teaching Hospital in Mosul from December 2006-January 2010, a detailed case-record of 20 consecutive newborn patients treated for duodenal obstruction. The aims of the study was to analyze our experience and to evaluate the clinical presentation, diagnosis, postoperative care, and outcome in infants with duodenal obstruction.The 20 patients were classified according to classification system modified from James A. O’Neill: duodenal web, atresia , annular pancreas and malrotation.The presumptive diagnosis and decision regarding the need for surgery was based on clinical findings and investigation of plain abdominal radiographs in all patients without the need of dye study. Abdominal ultrasound examination was done for all patient to evaluate the associated renal anomalies and echocardiogram was done for 15 patients because of suspicion of congenital heart disease.other laboratory investigation including complete blood count, serum electrolyte, blood urea and total serum bilirubin were done for all patients.the management strategy for all patients was outlined as follows: After initial evaluation, a nasogastric tube (NGT) was placed for gastric decompression. The operative procedures performed through supra umbilical transverse abdominal incision. The type of duodenal obstruction was assessed after mobilizing the ascending and transverse colon to the left and identifying any associated malrotation. Kocherization of duodenum then performed and a transpyloric tube was passed to determine if a windsock abnormality was present . In duodenal atresia intraoperatively injection of saline or air into the distal segment was done to rule out a second atresia. Using a single layer of interrupted suture with posterior knots tied inside and anterior knots tied outside by using 5-0 or 6-0 Vicryl (polyglactin) o Polydiaxonone suture(PDS) 5/0 to complete the anastamosis. The age of our patients were ranging from1day to 16 days and divided in to two groups from 1 up to 7 days. The Common clinical findings in our patients were bilious emesis, upper abdominal distension, failure to pass meconium . And accordingly the incidence of each symptoms and signs.The available investigations in our center at any time was the plain abdominal x ray, the finding in plain x-ray of abdomen was double bubble sign in 18(90%)of the patients and single gastric gas shadow in 2(10%) of patient. Abdominal ultrasound examination was done for all patients locking for any associated anomalies especially of the urinary tract. The finding was ectopic kidney in 1(5%) and hydronephrosis in 1(5%) of our patient. Echocardiography has been performed in 15 patients , abnormal in 2 male babies one of them had VSD and another one had ASD. Careful examination and follow up locking for associated anomalies were done and their types and percentile shows m
对2006年12月至2010年1月在摩苏尔AL Khanssa妇幼教学医院儿科外科中心进行的20例临床诊断为十二指肠梗阻的患者进行前瞻性研究，对20例连续接受十二指肠梗阻治疗的新生儿患者进行详细的病例记录。本研究的目的是分析我们的经验，并评估婴儿十二指肠梗阻的临床表现、诊断、术后护理和结局。根据James A. O 'Neill改良的分类系统对20例患者进行分类:十二指肠网、闭锁、环状胰腺和旋转不良。推定诊断和决定是否需要手术是基于临床表现和调查腹部平片的所有患者，不需要染料研究。所有患者均行腹部超声检查以评估相关肾脏异常，其中15例因怀疑有先天性心脏病而行超声心动图检查。其他实验室检查包括全血细胞计数、血清电解质、尿素和血清总胆红素。所有患者的处理策略概述如下:初步评估后，放置鼻胃管(NGT)进行胃减压。手术通过脐上腹部横切口进行。在将升结肠和横结肠向左移动并确定任何相关的旋转不良后，评估十二指肠梗阻的类型。然后行十二指肠Kocherization，并通过一根经幽门管来确定是否存在风袜异常。在十二指肠闭锁中，术中向远端段注射生理盐水或空气以排除第二次闭锁。采用5-0或6-0 Vicryl (polyglactin)或Polydiaxonone (PDS) 5/0缝合，采用单层间断缝合，后结在内侧，前结在外侧，完成吻合。我们的患者年龄从1天到16天不等，从1天到7天分为两组。本组患者常见的临床表现为胆汁性呕吐、上腹胀、胎便不能排出。并据此确定每种症状和体征的发生率。本中心可随时进行的检查为腹部x线平片，腹部x线平片表现为双泡征18例(90%)，单胃气影2例(10%)。腹部超声检查对所有患者锁定任何相关的异常，特别是泌尿道。结果发现1例(5%)患者肾异位，1例(5%)患者肾积水。超声心动图检查15例，2例男婴异常，其中1例为室间隔缺损，1例为ASD。对相关异常进行了仔细的检查和随访锁定，其类型和百分位数显示男性患者比女性患者有更多的相关异常。
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