Pub Date : 2024-01-01DOI: 10.32598/jgums.32.4.2094.1
Armin Ali golzadeh kenarsari, M. Yakhchali, Keyhan Ashrafi Fashi, M. Sharifdini
Background: Some freshwater snails are as intermediate hosts of human and animal parasitic trematode. Study on freshwater snails’ fauna and cercariae infection play important role to detect sources of infection. Objective: The aim of the present study was to determine diversity and cercariae infection of Lymnaeidae and Physidae freshwater snails and effects of physicochemical parameters of water on their abundance and distribution in Guilan province, North of Iran. Methods: Over one year, a total of 117 regions in Guilan province were investigated for Lymnaeidae and Physidae freshwater snails and identified. Water samples of each region was also collected for physicochemical analyses. Identified snails were examined for cercariae infection by shedding method. Results: Of 39,486 collected snails, three species of two genera including 19,726 Lymnaea auricularia (49.96%), 4911 L. palustris (12.44%), and 14849 Physa acuta (37.6%) were identified. Cercariae infection rate was 2.36%. Identified cercariae were xiphidiocercariae (0.94%), echinostome (0.8%), furcocercous (0.44%), lophocercous (0.16%), and gymnocephalous (0.02%). The highest infection rate was in spring (3.37%). Temperature and pH had inverse effect and salinity and water electrical conductivity had direct effects on snails’ density. Conclusion: Two genera of Lymnaea and Physa exist in examined aquatic habitats of Guilan province, North of Iran in different seasons of a year. The physicochemical parameters of water had effects on distribution and snails’ density and also abundance of cercariae infection in them.
{"title":"Prevalence of Cercariae Infection in Snails From the Lymnaeidae and Physidae Families in Aquatic Regions of Guilan Province, Northern Iran, and the Effect of Some Physicochemical Parameters of Water on Snail Abundance and Infection Rate","authors":"Armin Ali golzadeh kenarsari, M. Yakhchali, Keyhan Ashrafi Fashi, M. Sharifdini","doi":"10.32598/jgums.32.4.2094.1","DOIUrl":"https://doi.org/10.32598/jgums.32.4.2094.1","url":null,"abstract":"Background: Some freshwater snails are as intermediate hosts of human and animal parasitic trematode. Study on freshwater snails’ fauna and cercariae infection play important role to detect sources of infection. Objective: The aim of the present study was to determine diversity and cercariae infection of Lymnaeidae and Physidae freshwater snails and effects of physicochemical parameters of water on their abundance and distribution in Guilan province, North of Iran. Methods: Over one year, a total of 117 regions in Guilan province were investigated for Lymnaeidae and Physidae freshwater snails and identified. Water samples of each region was also collected for physicochemical analyses. Identified snails were examined for cercariae infection by shedding method. Results: Of 39,486 collected snails, three species of two genera including 19,726 Lymnaea auricularia (49.96%), 4911 L. palustris (12.44%), and 14849 Physa acuta (37.6%) were identified. Cercariae infection rate was 2.36%. Identified cercariae were xiphidiocercariae (0.94%), echinostome (0.8%), furcocercous (0.44%), lophocercous (0.16%), and gymnocephalous (0.02%). The highest infection rate was in spring (3.37%). Temperature and pH had inverse effect and salinity and water electrical conductivity had direct effects on snails’ density. Conclusion: Two genera of Lymnaea and Physa exist in examined aquatic habitats of Guilan province, North of Iran in different seasons of a year. The physicochemical parameters of water had effects on distribution and snails’ density and also abundance of cercariae infection in them.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"66 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140524949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.32598/jgums.32.4.2138.1
E. Alimohammadi, S. Bagheri, Kousar Mohammadi
Background: Paranasal sinus osteomas are benign, slow-growing tumors that are typically asymptomatic. However, in rare cases, these tumors can grow to a giant size and extend into neighboring structures such as the brain, orbit, or nasal cavity, leading to clinical symptoms. These symptoms may include chronic headaches, rhinorrhea, neurological deficits, and visual impairment. Case presentation: Here, we present the case of a 27-year-old male patient who presented to our hospital with chronic headaches and frequent sleep apnea. Upon rhinoscopic examination, mucosal polyposis was observed. Further evaluation through computed tomography revealed a giant fibroosseous tumor in the frontal sinus, which exhibited aggressive extension into the brain parenchyma. Contrast-enhanced magnetic resonance imaging confirmed the presence of a giant tumor with an 8 cm diameter, exerting a mass effect on the underlying brain tissue. To address this complex case, the patient underwent a combined transcranial and transnasal surgical approach. Following the surgery, the patient experienced significant improvement in his symptoms. Conclusions: This report highlights a rare case of sleep apnea secondary to a giant frontoethmoidal osteoma with intracranial extension. The presence of frontal sinus osteomas can lead to serious clinical consequences. Timely diagnosis and intervention are crucial to prevent intracranial extension and mitigate potential complications associated with these lesions.
{"title":"A Giant Frontoethmoidal Sinus Osteoma Presenting With Frequent Sleep Apnea Attacks: A Case Report","authors":"E. Alimohammadi, S. Bagheri, Kousar Mohammadi","doi":"10.32598/jgums.32.4.2138.1","DOIUrl":"https://doi.org/10.32598/jgums.32.4.2138.1","url":null,"abstract":"Background: Paranasal sinus osteomas are benign, slow-growing tumors that are typically asymptomatic. However, in rare cases, these tumors can grow to a giant size and extend into neighboring structures such as the brain, orbit, or nasal cavity, leading to clinical symptoms. These symptoms may include chronic headaches, rhinorrhea, neurological deficits, and visual impairment. Case presentation: Here, we present the case of a 27-year-old male patient who presented to our hospital with chronic headaches and frequent sleep apnea. Upon rhinoscopic examination, mucosal polyposis was observed. Further evaluation through computed tomography revealed a giant fibroosseous tumor in the frontal sinus, which exhibited aggressive extension into the brain parenchyma. Contrast-enhanced magnetic resonance imaging confirmed the presence of a giant tumor with an 8 cm diameter, exerting a mass effect on the underlying brain tissue. To address this complex case, the patient underwent a combined transcranial and transnasal surgical approach. Following the surgery, the patient experienced significant improvement in his symptoms. Conclusions: This report highlights a rare case of sleep apnea secondary to a giant frontoethmoidal osteoma with intracranial extension. The presence of frontal sinus osteomas can lead to serious clinical consequences. Timely diagnosis and intervention are crucial to prevent intracranial extension and mitigate potential complications associated with these lesions.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"285 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140521004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Cleft lip and palate are the most common congenital anomalies in the head and neck region, which are affected by environmental and genetic factors. These defects can cause serious problems such as deformity, nutritional, respiratory and social interactions for patients. Objective: The current study was performed to investigate the frequency of cleft lip and palate and its related factors in infants born in Karaj’s hospitals during 2014 to 2018. Methods: This descriptive-analytical study was conducted on the case of newborns. The studied population included 91,563 cases of babies born between 1993 and 1997 in Kamali, Imam Ali (AS), Maryam and Qaim hospitals in Karaj. Of these, 46 babies were identified with various types of oral clefts. The information of the files was collected and analyzed with SPSS v24 statistical software.. Results: The prevalence of oral cleft was 0.5 per thousand live births. (26.08%) of infants had cleft lip, (52.17%) cleft palate, and (21.73%) cleft lip and palate (P = 0.024). 56.52% of male babies (P = 0.37), 76.08% of mothers in the age group of 20 to 30 years with an average age of 24.4 years, 58.69% of first pregnancy mothers, 13.03% of parents, history Family marriage (P< 0.001), and 37% of mothers had blood type A in the file (P = 0.11). Conclusion: The prevalence of oral clefts in Karaj is lower than the global statistics and other regions of the country.
{"title":"Prevalence of Lip and Palate Clefts and the Related Factors in Babies Born From 2014 to 2019 in Karaj, Iran","authors":"Faraz Farahi Araghi, Seyed Mostafa Mortazavi, Samar Esmaeili, Masoume Esmaily","doi":"10.32598/jgums.32.4.1439.4","DOIUrl":"https://doi.org/10.32598/jgums.32.4.1439.4","url":null,"abstract":"Background: Cleft lip and palate are the most common congenital anomalies in the head and neck region, which are affected by environmental and genetic factors. These defects can cause serious problems such as deformity, nutritional, respiratory and social interactions for patients. Objective: The current study was performed to investigate the frequency of cleft lip and palate and its related factors in infants born in Karaj’s hospitals during 2014 to 2018. Methods: This descriptive-analytical study was conducted on the case of newborns. The studied population included 91,563 cases of babies born between 1993 and 1997 in Kamali, Imam Ali (AS), Maryam and Qaim hospitals in Karaj. Of these, 46 babies were identified with various types of oral clefts. The information of the files was collected and analyzed with SPSS v24 statistical software.. Results: The prevalence of oral cleft was 0.5 per thousand live births. (26.08%) of infants had cleft lip, (52.17%) cleft palate, and (21.73%) cleft lip and palate (P = 0.024). 56.52% of male babies (P = 0.37), 76.08% of mothers in the age group of 20 to 30 years with an average age of 24.4 years, 58.69% of first pregnancy mothers, 13.03% of parents, history Family marriage (P< 0.001), and 37% of mothers had blood type A in the file (P = 0.11). Conclusion: The prevalence of oral clefts in Karaj is lower than the global statistics and other regions of the country.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"26 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140518299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.32598/jgums.32.4.2089.1
B. Yahyaei, Hesamedin Babaei, Leila Khojasteh, Aref Arminfar, Ali Jorjani, Kimia Jannati Toupkanloo, Alireza Avazzadeh
Background: Nowadays, the importance of ketamine as a widely used drug in medicine, especially anesthesia, cannot be ignored. On the other hand, due to the increase in the number of different surgeries during pregnancy and the urgent need for a safe anesthetic agent, we decided to conduct this study to investigate the histological changes of the kidney, which is a vital organ in maintaining homeostasis and normal body function, in infants of maternal rats receiving injectable ketamine. Method: It was a laboratory field study that used fifteen female rats, which were randomly divided into three groups. The control groups, the group receiving short-term doses of ketamine through repeated injections and the group receiving long-term doses of ketamine. Then the histopathological changes of newborns resulting from the fertility of these rats was evaluated qualitatively with the help of an optical microscope. Result: In the short-term dose group, most of the glomeruli were normal in terms of morphology, only some of the glomeruli were disorganized and in a small number of them, shrinkage was observed. In the long-term dose group, some glomeruli had irregular size and shape, and the urinary space showed a small decrease. Also, the structure and shape of proximal and distal tubule cells were normal in both short-term and long-term groups. Conclusion: The qualitative changes of histopathology in both groups receiving short-term and long-term doses of ketamine were not significant compared to the control group.
{"title":"Histopathological Study of the Kidney Tissue of Neonatal Rats Born From Mothers Receiving Short-term and Long-term Ketamine Injections","authors":"B. Yahyaei, Hesamedin Babaei, Leila Khojasteh, Aref Arminfar, Ali Jorjani, Kimia Jannati Toupkanloo, Alireza Avazzadeh","doi":"10.32598/jgums.32.4.2089.1","DOIUrl":"https://doi.org/10.32598/jgums.32.4.2089.1","url":null,"abstract":"Background: Nowadays, the importance of ketamine as a widely used drug in medicine, especially anesthesia, cannot be ignored. On the other hand, due to the increase in the number of different surgeries during pregnancy and the urgent need for a safe anesthetic agent, we decided to conduct this study to investigate the histological changes of the kidney, which is a vital organ in maintaining homeostasis and normal body function, in infants of maternal rats receiving injectable ketamine. Method: It was a laboratory field study that used fifteen female rats, which were randomly divided into three groups. The control groups, the group receiving short-term doses of ketamine through repeated injections and the group receiving long-term doses of ketamine. Then the histopathological changes of newborns resulting from the fertility of these rats was evaluated qualitatively with the help of an optical microscope. Result: In the short-term dose group, most of the glomeruli were normal in terms of morphology, only some of the glomeruli were disorganized and in a small number of them, shrinkage was observed. In the long-term dose group, some glomeruli had irregular size and shape, and the urinary space showed a small decrease. Also, the structure and shape of proximal and distal tubule cells were normal in both short-term and long-term groups. Conclusion: The qualitative changes of histopathology in both groups receiving short-term and long-term doses of ketamine were not significant compared to the control group.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"37 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140522270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.32598/jgums.32.4.1719.1
Abbas Darjani, Sedigheh Norouzmehr, Hassan Abbaspour, Fataneh Imani, S. Soltanipour
Background: research theses can have a significant impact on the development of applied sciences, especially when their results are presented to the public. There are few studies about publishing papers based on residency and master’s theses. Objective: to determine publishing papers based on residency and master’s theses in Guilan University of Medical Sciences (GUMS) during 2008-2018. Methods: this descriptive cross-sectional study retrieved information on residency and master’s theses from 2008 to 2018. Then searched international and national medical databases according to the title of theses, keywords, and the names of supervisors, consultants, and students. Results: 449 (58. %) papers were published from 774 theses. 41.2%, 11.8%, 0.44% and, 46.56% were indexed in type one, two, three and, other types of scientific indexes respectively. 98.66% of papers were original articles. 383 (85.3%) of theses did not have statisticians’ consultants. And the maximum median time from defending theses to the publication of a paper was two years. Conclusion: publication of papers increased at GUMS compared to the past, and more than fifty percent were indexed in scientific indexes types one and two. However, associated factors with the publishing papers process should be surveyed.
背景：研究论文可对应用科学的发展产生重大影响，尤其是当其成果向公众展示时。有关根据住院医师和硕士论文发表论文的研究很少。目的：了解 2008-2018 年期间吉兰医科大学（Guilan University of Medical Sciences，GUMS）根据住院医师和硕士论文发表论文的情况。方法：这项描述性横断面研究检索了 2008 年至 2018 年的住院医师和硕士论文信息。然后根据论文标题、关键词以及导师、顾问和学生姓名检索国际和国内医学数据库。结果发现774篇论文中发表了449篇（58.分别有 41.2%、11.8%、0.44% 和 46.56% 的论文被一类、二类、三类和其他类型的科学索引收录。98.66%的论文为原创文章。383篇（85.3%）论文没有统计学家顾问。从论文答辩到论文发表的时间中位数最长为两年。结论：与过去相比，古米廖夫医学院发表的论文数量有所增加，50%以上的论文被第一类和第二类科学索引收录。但是，应该对论文发表过程中的相关因素进行调查。
{"title":"Publication Rate of Papers Extracted From the Medical Residency and Master’s Degree Theses of Guilan University of Medical Sciences From 2008 to 2018","authors":"Abbas Darjani, Sedigheh Norouzmehr, Hassan Abbaspour, Fataneh Imani, S. Soltanipour","doi":"10.32598/jgums.32.4.1719.1","DOIUrl":"https://doi.org/10.32598/jgums.32.4.1719.1","url":null,"abstract":"Background: research theses can have a significant impact on the development of applied sciences, especially when their results are presented to the public. There are few studies about publishing papers based on residency and master’s theses. Objective: to determine publishing papers based on residency and master’s theses in Guilan University of Medical Sciences (GUMS) during 2008-2018. Methods: this descriptive cross-sectional study retrieved information on residency and master’s theses from 2008 to 2018. Then searched international and national medical databases according to the title of theses, keywords, and the names of supervisors, consultants, and students. Results: 449 (58. %) papers were published from 774 theses. 41.2%, 11.8%, 0.44% and, 46.56% were indexed in type one, two, three and, other types of scientific indexes respectively. 98.66% of papers were original articles. 383 (85.3%) of theses did not have statisticians’ consultants. And the maximum median time from defending theses to the publication of a paper was two years. Conclusion: publication of papers increased at GUMS compared to the past, and more than fifty percent were indexed in scientific indexes types one and two. However, associated factors with the publishing papers process should be surveyed.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"155 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140521516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.32598/jgums.32.2.1880.3
K. Asadi, Masoud Fallah Khosh Ghalb, Khashayar Cyrus
Department of Orthopedics, Orthopedic Research Center, Faculty of Medicine, Poorsina Hospital, Guilan University of Medical Sciences, Rasht, Iran.
伊朗拉希特吉兰医科大学普尔西纳医院医学院骨科研究中心骨科
{"title":"Comparison of the Clinical Outcomes of Plastering and Bandage Treatment Methods in Patients With Ankle Sprains: A Randomized Clinical Trial Study","authors":"K. Asadi, Masoud Fallah Khosh Ghalb, Khashayar Cyrus","doi":"10.32598/jgums.32.2.1880.3","DOIUrl":"https://doi.org/10.32598/jgums.32.2.1880.3","url":null,"abstract":"Department of Orthopedics, Orthopedic Research Center, Faculty of Medicine, Poorsina Hospital, Guilan University of Medical Sciences, Rasht, Iran.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84565526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.32598/jgums.32.2.593.2
H. Boskabadi, M. Zakerihamidi, F. Bagheri, A. Taghipour
Background The proper diagnosis and treatment of neonatal sepsis is done depends on the understanding of its causative organisms. Objective The present study aimed to investigate the types of microorganisms in definitive neonatal sepsis. Methods Neonatal sepsis is a serious infectious disease with high mortality. And its diagnosed by blood culture. It includes early (appearance of clinical symptoms from birth to the third-seventh day) and late (from the third day to the twenty-eighth day) types with specific and sometimes common clinical symptoms. This cross-sectional study was performed on 266 neonates hospitalized with definitive sepsis in Ghaem Hospital in Mashhad from 2010 to 2020 using available sampling method. Infants suspected of bacterial infection who had positive blood cultures were included in the study. Type of bacterial organism, time of sepsis, main causes of death and need for mechanical ventilation were evaluated. Results Eighty eight neonates had early sepsis and 197 neonates had late sepsis. The bacterial organism of early sepsis was gram negative as 70.1% and in late sepsis was gram negative as 77.1%. The most common causes of early sepsis were Klebsiella pneumonia 21 cases (23.9%), Staphylococcus epidermis 16 cases (18.2%) and 10 cases (11.4%) E. coli . And the most common causes of late sepsis were K. pneumonia 35 cases (25.4%), Enterobacter aeroginosa 25(18.1%), S. epidermis 12(8.7%) and E. coli 11(8%). Conclusion K. pneumonia, S. epidermis and E. coli were three most common organisms in early neonatal sepsis and K. pneumonia, S. epidermis and Enterobacter were the most common organisms in late neonatal sepsis.
{"title":"Bacterial Microorganisms in Definitive Neonatal Sepsis","authors":"H. Boskabadi, M. Zakerihamidi, F. Bagheri, A. Taghipour","doi":"10.32598/jgums.32.2.593.2","DOIUrl":"https://doi.org/10.32598/jgums.32.2.593.2","url":null,"abstract":"Background The proper diagnosis and treatment of neonatal sepsis is done depends on the understanding of its causative organisms. Objective The present study aimed to investigate the types of microorganisms in definitive neonatal sepsis. Methods Neonatal sepsis is a serious infectious disease with high mortality. And its diagnosed by blood culture. It includes early (appearance of clinical symptoms from birth to the third-seventh day) and late (from the third day to the twenty-eighth day) types with specific and sometimes common clinical symptoms. This cross-sectional study was performed on 266 neonates hospitalized with definitive sepsis in Ghaem Hospital in Mashhad from 2010 to 2020 using available sampling method. Infants suspected of bacterial infection who had positive blood cultures were included in the study. Type of bacterial organism, time of sepsis, main causes of death and need for mechanical ventilation were evaluated. Results Eighty eight neonates had early sepsis and 197 neonates had late sepsis. The bacterial organism of early sepsis was gram negative as 70.1% and in late sepsis was gram negative as 77.1%. The most common causes of early sepsis were Klebsiella pneumonia 21 cases (23.9%), Staphylococcus epidermis 16 cases (18.2%) and 10 cases (11.4%) E. coli . And the most common causes of late sepsis were K. pneumonia 35 cases (25.4%), Enterobacter aeroginosa 25(18.1%), S. epidermis 12(8.7%) and E. coli 11(8%). Conclusion K. pneumonia, S. epidermis and E. coli were three most common organisms in early neonatal sepsis and K. pneumonia, S. epidermis and Enterobacter were the most common organisms in late neonatal sepsis.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79763445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.32598/jgums.32.2.1983.1
A. Salari, Vanousheh Norouzi, Fereshteh Naser Alavi
Background Periodontitis is an inflammatory disease with the production of cytokines that can lead to local and systemic inflammatory responses. On the other hand, during systemic inflammation in the body, the levels of acute phase proteins (APPs) can change. APPs include positive and negative types, which in response to inflammatory conditions, the concentration of positive types increases and negative types decreases. Therefore, examining changes in APPs can be used as a marker during periodontitis and periodontal treatment. Objective The purpose of this review article was to investigate the effect of periodontitis and periodontal treatment on positive APPs. The distinguishing feature of this article is the investigation of the effect of periodontal disease and its treatment on positive APPs. In addition, the introduction of new positive APPs in the future can be used to conduct new studies. Methods In this study, the keywords periodontitis, acute phase proteins, periodontal debridement, and inflammation mediators in English were searched in Google Scholar and PubMed and Scopus databases from 2000 to 2022. Among the found articles, finally, 65 related articles were selected and reviewed. Results Periodontal treatment can reduce the levels of positive APPs increased during periodontitis. Conclusion Periodontitis as an inflammatory disease can lead to changes in the levels of positive APPs leading to an increase in the levels of these proteins. Periodontal treatment, which includes non-surgical treatment (the first step of periodontal treatment and the gold standard of this treatment is scaling above and below the gums and leveling the root surfaces to remove etiological factors) and, if necessary, surgical treatment can lead to the reduction of their levels.
{"title":"Effect of Periodontitis and Periodontal Treatment on Positive Acute Phase Proteins","authors":"A. Salari, Vanousheh Norouzi, Fereshteh Naser Alavi","doi":"10.32598/jgums.32.2.1983.1","DOIUrl":"https://doi.org/10.32598/jgums.32.2.1983.1","url":null,"abstract":"Background Periodontitis is an inflammatory disease with the production of cytokines that can lead to local and systemic inflammatory responses. On the other hand, during systemic inflammation in the body, the levels of acute phase proteins (APPs) can change. APPs include positive and negative types, which in response to inflammatory conditions, the concentration of positive types increases and negative types decreases. Therefore, examining changes in APPs can be used as a marker during periodontitis and periodontal treatment. Objective The purpose of this review article was to investigate the effect of periodontitis and periodontal treatment on positive APPs. The distinguishing feature of this article is the investigation of the effect of periodontal disease and its treatment on positive APPs. In addition, the introduction of new positive APPs in the future can be used to conduct new studies. Methods In this study, the keywords periodontitis, acute phase proteins, periodontal debridement, and inflammation mediators in English were searched in Google Scholar and PubMed and Scopus databases from 2000 to 2022. Among the found articles, finally, 65 related articles were selected and reviewed. Results Periodontal treatment can reduce the levels of positive APPs increased during periodontitis. Conclusion Periodontitis as an inflammatory disease can lead to changes in the levels of positive APPs leading to an increase in the levels of these proteins. Periodontal treatment, which includes non-surgical treatment (the first step of periodontal treatment and the gold standard of this treatment is scaling above and below the gums and leveling the root surfaces to remove etiological factors) and, if necessary, surgical treatment can lead to the reduction of their levels.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77951050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.32598/jgums.32.2.2078.1
Mehdi Aghsami, Marjan Shariatpanahi, H. Montazeri, Negar Mottaghi-Dastjerdi
Background The rheologic, mechanical, and pharmacological characteristics of hyaluronic acid (HA) gels vary in terms of their specific crosslinking technologies. Objective To evaluate the various characteristics of selected HA gels available in Iran, using simple, inexpensive, and reproducible experimental tests are necessary to better understand their appropriateness for specific indications. Methods The HA gels produced by various crosslinking technologies were evaluated by three experiments, including cohesivity, resistance to stretch, and microscopic examination. The gels subjected to these experiments in this study included Neuramis, Desirial, Belotero, Restylane, and Juvéderm. Results We found that cohesivity was different among the gels so that Desirial was the least cohesive and Belotero was the most cohesive gel. Other HA gels were observed as partially cohesive. The resistance to stretch test confirmed the cohesivity results and Belotero had the most significant resistance. Microscopic examination of the HA gels showed HA particles of varying distribution and size. Belotero and Desirial were the gels with no particles visible under the microscope. Conclusion Simple and inexpensive laboratory tests help to understand the way that they can affect the specific gel performance, and may be beneficial for physicians to decide on the best product for a particular therapeutic indication.
{"title":"Evaluation of the Effects of Different Crosslinking Technologies on Hyaluronic Acid Behavior-study of Five Hyaluronic Acid Gels Available in Iran Market","authors":"Mehdi Aghsami, Marjan Shariatpanahi, H. Montazeri, Negar Mottaghi-Dastjerdi","doi":"10.32598/jgums.32.2.2078.1","DOIUrl":"https://doi.org/10.32598/jgums.32.2.2078.1","url":null,"abstract":"Background The rheologic, mechanical, and pharmacological characteristics of hyaluronic acid (HA) gels vary in terms of their specific crosslinking technologies. Objective To evaluate the various characteristics of selected HA gels available in Iran, using simple, inexpensive, and reproducible experimental tests are necessary to better understand their appropriateness for specific indications. Methods The HA gels produced by various crosslinking technologies were evaluated by three experiments, including cohesivity, resistance to stretch, and microscopic examination. The gels subjected to these experiments in this study included Neuramis, Desirial, Belotero, Restylane, and Juvéderm. Results We found that cohesivity was different among the gels so that Desirial was the least cohesive and Belotero was the most cohesive gel. Other HA gels were observed as partially cohesive. The resistance to stretch test confirmed the cohesivity results and Belotero had the most significant resistance. Microscopic examination of the HA gels showed HA particles of varying distribution and size. Belotero and Desirial were the gels with no particles visible under the microscope. Conclusion Simple and inexpensive laboratory tests help to understand the way that they can affect the specific gel performance, and may be beneficial for physicians to decide on the best product for a particular therapeutic indication.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88783179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.32598/jgums.32.2.1977.1
Seyyed AbdolKarim Ghasemi, A. G. Chamanabad, Seyyed Rouhollah Hosseini, AmirMohammad Mahdinia, Zohreh Teymori, Sajjad Abbaszade
Background Technology-based interventions, such as electrical brain stimulation may be effective in the cognitive and personality processes of substance abusers, including nicotine dependents. Objective We conducted this study to investigate the effectiveness of transcranial alternating current stimulation (tACS) using alpha frequency on inhibitory control and impulsivity in nicotine-dependent individuals. Methods We used a pre-test/post-test/follow-up quasi-experimental design with control and sham groups. We selected 30 eligible nicotine addicts from Mashhad using the available sampling method and randomly divided the subjects into three groups. We applied the intervention in eight sessions for 20 minutes in the dorsolateral prefrontal cortex for the first group, fake interventions for the second group, and no intervention for the third group. The Fagerström questionnaire, Barrett impulsivity questionnaire, and go-no-go task were used to collect data. After eight sessions, people’s inhibitory control and impulsivity were evaluated and analyzed using multivariate analysis of covariance (MANCOVA). Also, after two months, we evaluated inhibitory control data with repeated-measures analysis of variance. Results The effectiveness of alpha-tACS intervention on short- and long-term inhibitory control was significantly different in the experimental group compared to other groups (P=0.001). There was no significant difference between these three groups in impulsivity (P=0.700). Conclusion Alpha-tACS intervention effectively increases inhibitory control in nicotine-dependent individuals but does not explicitly affect their impulsivity.
{"title":"Effectiveness of Transcranial Alternating Current Stimulation on Inhibitory Control and Impulsivity in Nicotine-dependent Individuals","authors":"Seyyed AbdolKarim Ghasemi, A. G. Chamanabad, Seyyed Rouhollah Hosseini, AmirMohammad Mahdinia, Zohreh Teymori, Sajjad Abbaszade","doi":"10.32598/jgums.32.2.1977.1","DOIUrl":"https://doi.org/10.32598/jgums.32.2.1977.1","url":null,"abstract":"Background Technology-based interventions, such as electrical brain stimulation may be effective in the cognitive and personality processes of substance abusers, including nicotine dependents. Objective We conducted this study to investigate the effectiveness of transcranial alternating current stimulation (tACS) using alpha frequency on inhibitory control and impulsivity in nicotine-dependent individuals. Methods We used a pre-test/post-test/follow-up quasi-experimental design with control and sham groups. We selected 30 eligible nicotine addicts from Mashhad using the available sampling method and randomly divided the subjects into three groups. We applied the intervention in eight sessions for 20 minutes in the dorsolateral prefrontal cortex for the first group, fake interventions for the second group, and no intervention for the third group. The Fagerström questionnaire, Barrett impulsivity questionnaire, and go-no-go task were used to collect data. After eight sessions, people’s inhibitory control and impulsivity were evaluated and analyzed using multivariate analysis of covariance (MANCOVA). Also, after two months, we evaluated inhibitory control data with repeated-measures analysis of variance. Results The effectiveness of alpha-tACS intervention on short- and long-term inhibitory control was significantly different in the experimental group compared to other groups (P=0.001). There was no significant difference between these three groups in impulsivity (P=0.700). Conclusion Alpha-tACS intervention effectively increases inhibitory control in nicotine-dependent individuals but does not explicitly affect their impulsivity.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"110 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79605475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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