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Hypnotherapy in cancer care: Clinical benefits and prospective implications 催眠疗法在癌症治疗中的应用:临床益处和前瞻性意义
Pub Date : 2017-09-01 DOI: 10.4103/JHRR.JHRR_45_17
V. Sharma
The aim of this review is to summarize data published on the use of hypnotherapy in cancer patients. Cancer is probably a disease people fear the most. Indeed, the majority of cancer patients experience stress, anxiety, depression, nausea, vomiting, fatigue, and pain. Medical treatments of cancer such as radiotherapy, chemotherapy, and surgery are clearly necessary but can affect patients on different levels and hence have a negative impact on physical and mental health. This review examines the effect of clinical hypnotherapy performed in cancer care, particularly on psychological disturbances, pain, and fatigue. A literature search of relevant literature was performed from February 2016 to October 2016. CINAHL, MEDLINE, PsycINFO, PubMed, and ScienceDaily databases were searched using search terms for mind–body intervention “hypnotherapy,” “hypnosis,” and “hypnotism” combined with the term “cancer” and terms for symptoms of interest “pain,” “mood disturbances,” “psychological disturbances,” “fatigue,” “anger,” “aggression,” “anxiety,” “tension,” “depression,” “confusion,” “delirium,” “vigour.” English language peer-reviewed articles, randomized trials, and reviews were selected. A first extensive literature review resulted in 98 articles. Finally, 55 research papers were identified for further review and analysis. On the basis of review of previous researches, it can be concluded that hypnotherapy seems to improve the mental health as well as physical health in cancer patients. Moreover, of course, randomized prospective studies are now needed to confirm the observed advantages of hypnosis in the field of oncology.
本综述的目的是总结已发表的关于催眠疗法在癌症患者中的应用的数据。癌症可能是人们最害怕的一种疾病。事实上,大多数癌症患者都会经历压力、焦虑、抑郁、恶心、呕吐、疲劳和疼痛。癌症的医学治疗,如放疗、化疗和手术,显然是必要的,但会在不同程度上影响患者,从而对身心健康产生负面影响。这篇综述探讨了临床催眠疗法在癌症治疗中的作用,特别是对心理障碍、疼痛和疲劳的治疗。于2016年2月至2016年10月对相关文献进行文献检索。CINAHL, MEDLINE, PsycINFO, PubMed和ScienceDaily数据库使用身心干预的搜索词“催眠疗法”,“催眠”和“催眠”结合术语“癌症”和感兴趣的症状术语“疼痛”,“情绪障碍”,“心理障碍”,“疲劳”,“愤怒”,“攻击”,“焦虑”,“紧张”,“抑郁”,“困惑”,“谵癫”,“活力”进行搜索。选择英文同行评议的文章、随机试验和评论。第一次广泛的文献综述得出了98篇文章。最后,选取55篇研究论文进行进一步的回顾和分析。在回顾以往研究的基础上,我们可以得出结论,催眠疗法似乎可以改善癌症患者的心理健康和身体健康。此外,当然,现在需要随机前瞻性研究来证实催眠在肿瘤领域的优势。
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引用次数: 5
Correlation of body mass index and blood pressure of adults of 30–50 years of age in Ghana 加纳30-50岁成年人体重指数与血压的相关性
Pub Date : 2017-09-01 DOI: 10.4103/JHRR.JHRR_93_16
F. Vuvor
Aims: There is an increase in the prevalence rates of overweight and obesity across the globe. Blood pressure (BP) has been found to increase among populations with high body mass index (BMI). Overweight and high BP both have independent fatal health consequences as they carry serious risk factors for several noncommunicable diseases such as heart disease, stroke, type II diabetes, and even death. It is against this background that this research was carried out to corroborate similar result in Ghana. The objective of this study was to determine the correlation of BMI and BP of adults of 30–50 years. Materials and Methods: the WHO STEPwise questionnaires modified to obtain information on demography and lifestyle. Weight and height were measured using seca scale and stadiometer, respectively. BP was also recorded using digital sphygmomanometer. A 24-h recall method was used to assess the dietary intake of participants. Results: The prevalence of overweight and obesity was found to be 20.0% and 7.5%, respectively. About 32.5% of the participants (200) were hypertensive (systolic blood pressure [SBP] ≥140 mm Hg). A significant difference existed between high and normal SBP of the participants (P = 0.01). Conclusion: An increase in BMI positively influenced BP among these study adults' population.
目的:在全球范围内,超重和肥胖的患病率有所上升。研究发现,在身体质量指数(BMI)较高的人群中,血压(BP)升高。超重和高血压都有独立的致命健康后果,因为它们携带一些非传染性疾病的严重危险因素,如心脏病、中风、II型糖尿病,甚至死亡。正是在这种背景下进行了这项研究,以证实加纳的类似结果。本研究的目的是确定30-50岁成年人BMI和BP的相关性。材料与方法:采用世界卫生组织step - wise问卷进行修改,获取人口学和生活方式信息。体重和身高分别用体重计和体重计测量。用数字血压计记录血压。采用24小时回忆法评估参与者的饮食摄入量。结果:超重和肥胖的患病率分别为20.0%和7.5%。约32.5%的参与者(200人)患有高血压(收缩压[SBP]≥140 mm Hg)。高收缩压组与正常收缩压组差异有统计学意义(P = 0.01)。结论:BMI升高对研究人群的血压有积极影响。
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引用次数: 22
Epidemiology and antimicrobial resistance of community-acquired pneumonia in children 儿童社区获得性肺炎流行病学及耐药性分析
Pub Date : 2017-09-01 DOI: 10.4103/JHRR.JHRR_75_15
M. Mansour, K. A. Al Hadidi, M. Hamed
Background: Community-acquired pneumonia (CAP) is a common serious infection in childhood. Bacterial resistance is widespread, with large geographical variations related to behaviors in antibiotics prescription. Identification of etiologic organisms of CAP and their resistance pattern must be done to guide the physicians for proper antimicrobial use. Aim: To identify the causative organisms most frequently isolated from children hospitalized for pneumonia and analyze their susceptibility to the antimicrobial agents most often used in pediatric practice. Materials and Methods: Two hundred and ninety-six immunocompetent children hospitalized in Jeddah Clinic Hospital with CAP from January 2010 to September 2011 were enrolled in the study. Their ages ranged between 6 weeks and 15 years. Chest radiograph, complete blood count test (CBC), C-reactive protein, test and sputum culture and sensitivity were done for all patients. Results: One hundred and nine (35.82%) participants were infants < 1 year, 43.58% were >1 year ≤5 years, and 20.6% were >5 years. A pathogen was identified in 34.12% of sputum cultures, 56.4% were typical respiratory pathogenic bacteria while 43.56% were normal commensals. Sputum cultures grew Streptococcus pneumonia in 8.77% of respiratory pathogens, coagulase positive Staphylococcus (19.3%), Group B β-hemolytic Streptococcus (8.77%), Escherichia coli (33.3%), Klebsiella spp. (14%), and Pseudomonas (14%). High antimicrobial resistance was recorded for penicillin, amoxicillin-clavulanate, cefaclor, cephalexin, and cefuroxime in Gram-positive organisms. Twenty-one percent of E. coli and 50% of Klebsiella spp. were resistant to spectrin. Conclusions: Higher incidence of CAP due to E. coli was recorded. There is increasing antimicrobial resistance to penicillin and second-generation cephalosporin.
背景:社区获得性肺炎(CAP)是儿童常见的严重感染。细菌耐药是普遍存在的,与抗生素处方行为有很大的地理差异。必须鉴定CAP的病原微生物及其耐药模式,以指导医生正确使用抗菌药物。目的:鉴定肺炎住院儿童中最常见的病原菌,并分析其对儿科常用抗菌药物的敏感性。材料与方法:选取2010年1月至2011年9月在吉达诊所医院住院的260名免疫功能正常的CAP患儿作为研究对象。他们的年龄在6周到15岁之间。所有患者均行胸片、全血细胞计数(CBC)、c反应蛋白、试验、痰培养及敏感性检查。结果:婴儿< 1岁者109例(35.82%),>1岁≤5岁者43.58%,>5岁者20.6%。痰培养检出病原菌34.12%,其中典型呼吸道致病菌56.4%,正常共生菌43.56%。痰培养中呼吸道病原菌中有肺炎链球菌(8.77%)、凝固酶阳性葡萄球菌(19.3%)、B群β溶血性链球菌(8.77%)、大肠埃希菌(33.3%)、克雷伯氏菌(14%)、假单胞菌(14%)。革兰氏阳性菌对青霉素、阿莫西林-克拉维酸盐、头孢克洛、头孢氨苄和头孢呋辛有高度耐药性。21%的大肠杆菌和50%的克雷伯氏菌对spectrin有抗药性。结论:大肠杆菌引起的CAP发生率较高。对青霉素和第二代头孢菌素的耐药性日益增加。
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引用次数: 2
Increased role of nonalbicans Candida, potential risk factors, and attributable mortality in hospitalized patients 非白色念珠菌在住院患者中的作用、潜在危险因素和归因死亡率增加
Pub Date : 2017-05-01 DOI: 10.4103/2394-2010.208115
R. Sandhu, S. Dahiya, P. Sayal, Diksha Budhani
Aim: The aim of this study was to evaluate the distribution of nonalbicans Candida (NAC) along with their associated risk factors, clinical outcome, and antifungal susceptibility pattern among inpatients. Materials and Methods: Retrospective descriptive study comprising 94 isolates of Candida species obtained from various clinical specimens of hospitalized patients. The clinical charts of patients were reviewed retrospectively who stayed in the hospital for more than 7 days irrespective of their diagnosis. Statistical Analysis: Descriptive statistics was used which involves the use of simple percentage and bar chart to analyze the data. In addition, Chi-square test was performed and P value was calculated. Results: NAC was identified in 72 (77%) patients and Candida albicans in 22 (23%). Factors associated with Candida krusei were stay in hospital ≥15 days (78%), broad-spectrum antimicrobial therapy (72%), prophylactic fluconazole therapy (67%), preterm newborn with low birth weight (LBW) (67%), stay in the Intensive Care Unit (ICU) ≥10 days (67%), indwelling devices (67%), and mechanical ventilation (67%); Candida glabrata infection as broad-spectrum antimicrobial therapy (69%), preterm newborn with LBW (62%), stay in ICU ≥10 days (62%), and indwelling devices (62%); Candida tropicalis as indwelling devices (86%), broad-spectrum antimicrobial therapy (71%), stay in ICU ≥10 days (71%), stay in hospital ≥15 days (71%), pulmonary tuberculosis (71%), neutropenia (71%). Amphotericin B was effective against both C. albicans as well as NAC with susceptibility of 91% and 89%, respectively. Mortality was similar in patients infected with C. albicans and nonalbicans species (27.27% vs. 27.77%). Conclusion: The study concludes higher prevalence of NAC with majority of patients having multiple underlying illnesses and other associated risk factors. Continued surveillance of Candida infections will be required to document changes in epidemiology and antifungal susceptibilities.
目的:本研究的目的是评估非白色念珠菌(NAC)在住院患者中的分布及其相关的危险因素、临床结果和抗真菌药敏模式。材料和方法:回顾性描述性研究,包括从住院患者的各种临床标本中分离的94株念珠菌。回顾性回顾了住院7天以上的患者的临床图表,无论其诊断如何。统计分析:使用描述性统计,包括使用简单的百分比和条形图来分析数据。并进行卡方检验,计算P值。结果:72例(77%)患者检出NAC, 22例(23%)患者检出白色念珠菌。与克鲁氏念珠菌相关的因素为住院≥15天(78%)、广谱抗菌药物治疗(72%)、预防性氟康唑治疗(67%)、低出生体重早产儿(67%)、重症监护病房(ICU)住院≥10天(67%)、留置装置(67%)和机械通气(67%);光秃念珠菌感染作为广谱抗菌药物治疗(69%),早产新生儿伴LBW (62%), ICU住院≥10天(62%),留置装置(62%);热带念珠菌留置器(86%)、广谱抗菌药物(71%)、ICU住院≥10天(71%)、住院≥15天(71%)、肺结核(71%)、中性粒细胞减少(71%)。两性霉素B对白色念珠菌和NAC均有效,敏感性分别为91%和89%。感染白色念珠菌和非白色念珠菌的患者死亡率相似(27.27% vs. 27.77%)。结论:研究表明,NAC的患病率较高,大多数患者有多种潜在疾病和其他相关危险因素。需要继续监测念珠菌感染,以记录流行病学和抗真菌敏感性的变化。
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引用次数: 16
Interventions in the management of blood viscosity for idiopathic sudden sensorineural hearing loss: A meta-analysis 特发性突发性感音神经性听力损失患者血液粘度管理的干预措施:一项荟萃分析
Pub Date : 2017-05-01 DOI: 10.4103/JHRR.JHRR_125_16
Yike Li
Aims and Objectives: To estimate the efficacy of interventions in the management of blood viscosity for idiopathic sudden sensorineural hearing loss (ISSNHL) using meta-analysis method. Materials and Methods: An extensive search for literature was performed to identify publications from 1966 to 2016 in Cochrane controlled clinical trials register online, Medline, EMBASE, BIOSIS Preview, Web of Science, China Knowledge Resource Integrated Database and Wanfang. Only randomized control trials (RCTs) with valid control groups were included in this study. Each trial was graded for methodological quality using a 6-point standard. Meta-analysis was performed to assess the efficacy of intervention in managing blood viscosity on hearing improvement (primary outcome), relief of tinnitus and vertigo (secondary outcomes) for ISSNHL. Tests for sensitivity, heterogeneity as well as publication bias were also performed to evaluate the validity of results. Results: Forty-nine RCTs with a total of 4978 patients were included in this meta-analysis. The overall odds ratio of all interventions was 3.12 (P < 0.01). Significant effect sizes were shown on fibrinogen reduction, plasmapheresis, and anticoagulation as well as hemodilution. The mean methodological score was 3.0. There was great homogeneity between studies. No evidence of publication bias was found. Sensitivity test showed reliability and robustness of the results. Conclusion: This meta-analysis provided evidence to support the effect of interventions that manage blood viscosity in the treatment of ISSNHL. There is a need for more high-quality RCTs in the future, especially for hemodilution, anticoagulation as well as plasmapheresis.
目的和目的:采用荟萃分析方法评估干预措施对特发性突发性感音神经性听力损失(ISSNHL)患者血液粘度管理的效果。材料与方法:广泛检索Cochrane在线对照临床试验注册、Medline、EMBASE、BIOSIS预览、Web of Science、中国知识资源综合数据库和万方数据库中1966 - 2016年发表的文献。本研究仅纳入具有有效对照组的随机对照试验(RCTs)。每个试验采用6分标准对方法学质量进行评分。荟萃分析评估了干预血液粘度对ISSNHL患者听力改善(主要结局)、耳鸣和眩晕缓解(次要结局)的效果。还进行了敏感性、异质性和发表偏倚检验,以评估结果的有效性。结果:49项随机对照试验共纳入4978例患者。各干预措施的总优势比为3.12 (P < 0.01)。在纤维蛋白原减少、血浆置换、抗凝和血液稀释方面显示了显著的效应值。平均方法评分为3.0分。研究之间有很大的一致性。未发现发表偏倚的证据。敏感性检验表明结果具有可靠性和稳健性。结论:本荟萃分析提供了证据,支持控制血液粘度的干预措施在ISSNHL治疗中的作用。未来需要更多高质量的随机对照试验,特别是血液稀释、抗凝和血浆置换。
{"title":"Interventions in the management of blood viscosity for idiopathic sudden sensorineural hearing loss: A meta-analysis","authors":"Yike Li","doi":"10.4103/JHRR.JHRR_125_16","DOIUrl":"https://doi.org/10.4103/JHRR.JHRR_125_16","url":null,"abstract":"Aims and Objectives: To estimate the efficacy of interventions in the management of blood viscosity for idiopathic sudden sensorineural hearing loss (ISSNHL) using meta-analysis method. Materials and Methods: An extensive search for literature was performed to identify publications from 1966 to 2016 in Cochrane controlled clinical trials register online, Medline, EMBASE, BIOSIS Preview, Web of Science, China Knowledge Resource Integrated Database and Wanfang. Only randomized control trials (RCTs) with valid control groups were included in this study. Each trial was graded for methodological quality using a 6-point standard. Meta-analysis was performed to assess the efficacy of intervention in managing blood viscosity on hearing improvement (primary outcome), relief of tinnitus and vertigo (secondary outcomes) for ISSNHL. Tests for sensitivity, heterogeneity as well as publication bias were also performed to evaluate the validity of results. Results: Forty-nine RCTs with a total of 4978 patients were included in this meta-analysis. The overall odds ratio of all interventions was 3.12 (P < 0.01). Significant effect sizes were shown on fibrinogen reduction, plasmapheresis, and anticoagulation as well as hemodilution. The mean methodological score was 3.0. There was great homogeneity between studies. No evidence of publication bias was found. Sensitivity test showed reliability and robustness of the results. Conclusion: This meta-analysis provided evidence to support the effect of interventions that manage blood viscosity in the treatment of ISSNHL. There is a need for more high-quality RCTs in the future, especially for hemodilution, anticoagulation as well as plasmapheresis.","PeriodicalId":16068,"journal":{"name":"Journal of Health Research and Reviews","volume":"24 1","pages":"50 - 61"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85488738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
The effects of maxillomandibular fixation on ventilatory functions in adult Nigerians 上颌下颌固定对尼日利亚成人通气功能的影响
Pub Date : 2017-05-01 DOI: 10.4103/JHRR.JHRR_102_16
B. Akhiwu, D. Saheeb, H. Akhiwu, D. Osunde, B. Ojukwu, M. Babashani
Background: Maxillomandibular fixation (MMF) is a routine procedure in maxillofacial surgery in developing countries. Aim: The aim of this study was to determine the pulmonary functions (forced expiratory volume in 1 min [FEV1], forced vital capacity [FVC], and peak expiratory flow rate [PEFR]) of adult Nigerian patients who had MMF and to find the associated changes in pulmonary functions in the postoperative period vis-à -vis pulmonary function tests among healthy adult Nigerians. Settings and Design: The study setting was the Oral and Maxillofacial Surgery Department of a Teaching Hospital in Northern Nigeria, and the study design was prospective hospital based. Materials and Methods: One hundred and six patients and 106 controls were recruited between January 2011 and December 2012. Information was obtained using a questionnaire. All study participants had their baseline lung functions measured; the treatment group in addition had their postoperative daily lung function parameters measured for the 1st week and then weekly for the next 5 weeks. Statistical Analysis: Statistical analyses were performed using the Statistical Package for Social Sciences (version 16, SPSS Inc., Chicago, IL, USA). The mean and standard deviation values of physical characteristics and ventilatory functions were determined in both men and women. The mean values were compared using Student's t-test. Statistical significance was inferred at P ≤ 0.05. Results: One hundred and seventy males and 42 females participated in the study. The control group had a mean age of 30.25 ± 9.05, weight 64.08 ± 9.90, height 1.67 ± 0.10, body mass index (BMI) 23.32 ± 3.07, basal FVC 3.70 ± 0.71, basal FEV13.16 ± 0.54, and basal PEFR8.35 ± 1.62. For the treatment group, the mean age was 30.68 ± 8.23, weight 64.91 ± 9.96, height 1.66 ± 0.10, BMI 23.21 ± 3.14, basal FVC 3.72 ± 0.69, basal FEV13.14 ± 0.51, and the basal PEFR8.18 ± 1.61. Conclusion: The postoperative mean FVC, FEV1, and PEFRvalues drop significantly by more than 50% when compared to the preoperative values in the first postoperative week with the nadir on the second postoperative day in the patients with MMF.
背景:上颌下颌固定(MMF)是发展中国家颌面外科的常规手术。目的:本研究的目的是确定尼日利亚成年MMF患者的肺功能(1分钟用力呼气量[FEV1]、用力肺活量[FVC]和呼气流量峰值[PEFR]),并通过对比肺功能测试在尼日利亚健康成人患者中发现术后肺功能的相关变化。环境与设计:研究环境为尼日利亚北部某教学医院口腔颌面外科,研究设计为前瞻性医院。材料与方法:2011年1月至2012年12月招募106例患者和106例对照。通过问卷调查获得信息。所有研究参与者都测量了他们的基线肺功能;治疗组术后第1周每日测量肺功能参数,随后5周每周测量一次。统计分析:使用Statistical Package for Social Sciences (version 16, SPSS Inc., Chicago, IL, USA)进行统计分析。测定男性和女性的身体特征和通气功能的平均值和标准差值。采用学生t检验比较平均值。P≤0.05,差异有统计学意义。结果:170名男性和42名女性参与了这项研究。对照组平均年龄30.25±9.05,体重64.08±9.90,身高1.67±0.10,体质指数(BMI) 23.32±3.07,FVC基础3.70±0.71,fev基础13.16±0.54,pefr基础8.35±1.62。治疗组平均年龄30.68±8.23,体重64.91±9.96,身高1.66±0.10,BMI 23.21±3.14,FVC基础3.72±0.69,fev基础13.14±0.51,pefr基础8.18±1.61。结论:MMF患者术后平均FVC、FEV1、pefr3值较术前在术后第一周显著下降50%以上,术后第2天达到最低点。
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引用次数: 0
Correlation of waist circumference and waist-to-height ratio with maximal aerobic capacity in young adults 年轻人腰围、腰高比与最大有氧能力的相关性
Pub Date : 2017-05-01 DOI: 10.4103/JHRR.JHRR_5_17
Himel Mondal, S. Mishra
Background: Central obesity or abdominal obesity doubles the risk of cardiovascular disease when compared to gynoid pattern of fat distribution. Maximal oxygen consumption (V.O2max) is an index of aerobic capacity and low level of V.O2maxis an established risk factor for cardiovascular diseases. Aim: This study aimed to evaluate the effect of central obesity on V.O2maxin young adults. Materials and Methods: A cross-sectional study with 133 apparently healthy subjects (male = 83, female = 50) in the age group of 17–25 years was carried out. Waist circumference (WC) was measured by fiberglass measuring tape to nearest 0.1 cm. V.O2maxwas measured by submaximal treadmill exercise test by first two stages of Bruce protocol. Data were analyzed using unpaired t-test and Pearson correlation according to necessity. Results: Male subjects (n = 83) had statistically significant (P < 0.0001) higher V.O2max(mean ± standard deviation) (38.024 ± 6.243) than the female subjects (n = 50) (33.611 ± 3.470). WC showed negative correlation with V.O2max(r = −0.629, P < 0.0001). Waist-to-height ratio (WHtR) showed more negative correlation (r = −0.728, P < 0.0001) with V.O2max. Conclusions: Male has more aerobic capacity than female. Increase in WC and WHtR are associated with decreases in V.O2max. When compared to WC, WHtR is better predictor variable for V.O2max.
背景:中心性肥胖或腹部肥胖与女性型脂肪分布相比,患心血管疾病的风险增加一倍。最大耗氧量(V.O2max)是有氧能力的指标,低水平的V.O2max是心血管疾病的确定危险因素。目的:探讨中心性肥胖对青壮年v2maxin的影响。材料与方法:采用横断面研究方法,选取17 ~ 25岁年龄层表面健康者133例(男83例,女50例)。腰围(WC)用玻璃纤维卷尺测量至最接近0.1 cm。采用Bruce方案前两阶段的次极限跑步机运动试验测量vo2max。根据需要对数据进行非配对t检验和Pearson相关分析。结果:男性受试者(n = 83)的V.O2max(平均值±标准差)(38.024±6.243)高于女性受试者(n = 50)(33.611±3.470),差异有统计学意义(P < 0.0001)。WC与V.O2max呈负相关(r = - 0.629, P < 0.0001)。腰高比(WHtR)与V.O2max呈负相关(r = - 0.728, P < 0.0001)。结论:男性的有氧能力高于女性。WC和WHtR的增加与vo2max的降低相关。与WC相比,WHtR是V.O2max更好的预测变量。
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引用次数: 5
Quantifying variation in blood pressure measurement through different arm cuffs and estimating its impact on diagnosis of hypertension at community level 量化不同袖带测量血压的差异,评估其对社区高血压诊断的影响
Pub Date : 2017-05-01 DOI: 10.4103/2394-2010.208121
B. Mishra, N. Sinha, Habib ur Rehman
Aims: The aim of this study was to analyze does the difference in blood pressure (BP) measured by different arm cuffs has a clinical/diagnostic implication? Settings and Design: This study was a cross-sectional evaluation of sample rural population from Central India. Materials and Methods: Three different adult arm cuffs were used on a selected 394 rural population from 35 to 65 years age group to estimate BP. Their BP was taken on three different times of the day on three different occasions/days. Statistical Analysis: Basic sociodemographic profiles were expressed in frequency and percentages; relationships of hypertension (HTN) with sociodemographic and other risk factors were calculated by Chi-square test; variability in BP by different arm cuffs was expressed by mean, standard deviations, and ANOVA; and prevalence difference of HTN by different arm cuffs was expressed by frequency, percentage, paired t- test, and Chi-square test. Results and Conclusions: The routinely used small adult cuff was found appropriate in only 3.8% of cases studied, thereby highlighting the prevalence of under cuffing at 96.2%. The mean variation in systolic and diastolic BP recorded by using small adult arm cuff vs. medium arm cuff and small arm cuff vs. large arm cuffs were 5.9mm Hg/4.4mm Hg and 9mmHg/7.2mmHg respectively. These observations were both clinically and statistically significant. Our study reported an overestimation of 4.8% systolic and 15% diastolic HTN by the exclusive use of small adult arm cuff. The prevalence of systolic, diastolic, and both systolic and diastolic HTN in selected age group using the correct arm cuff was found to be 20.8%, 29.6%, and 37.5%, respectively. Thus, arm cuff mismatch was a prevalent cause in misdiagnosis of primary HTN in our study population.
目的:本研究的目的是分析不同袖带测量的血压(BP)差异是否具有临床/诊断意义?背景和设计:本研究是对印度中部农村人口样本的横断面评估。材料与方法:选取394名35 ~ 65岁的农村人口,使用三种不同的成人臂套来估计血压。他们的血压是在一天中三个不同的时间、三个不同的场合/天测量的。统计分析:以频率和百分比表示基本的社会人口概况;采用卡方检验计算高血压(HTN)与社会人口学及其他危险因素的关系;通过均值、标准差和方差分析来表达不同袖带对血压的可变性;采用频率、百分比、配对t检验和卡方检验表示不同袖带对HTN的患病率差异。结果与结论:常规使用的成人小袖带仅适用于3.8%的研究病例,因此突出了96.2%的低袖带患病率。使用成人小臂袖与中臂袖、小臂袖与大臂袖记录的收缩压和舒张压平均变化分别为5.9mm Hg/4.4mm Hg和9mmHg/7.2mmHg。这些观察结果具有临床和统计学意义。我们的研究报告了仅使用成人小臂袖带可高估4.8%收缩期和15%舒张期HTN。在使用正确袖带的特定年龄组中,收缩期、舒张期以及收缩期和舒张期HTN的患病率分别为20.8%、29.6%和37.5%。因此,在我们的研究人群中,臂袖不匹配是原发性HTN误诊的一个普遍原因。
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引用次数: 4
Health supplements, patient behavior, concordance-does anybody bother? 健康补品,病人行为,和谐——有人在意吗?
Pub Date : 2017-05-01 DOI: 10.4103/jhrr.jhrr_19_17
N. Kamat
Naturally available fruits and vegetables along with a healthy diet does provide all required nutrients to the body. Then why do people go behind the so-called “health supplements” - vitamins, minerals, herbal immune booster, probiotics, tonics, etc? Do you really need them? Patients in India are desperate to grab the shortcut to good health. They buy products which are unnecessary and which do not have any beneficial effect. On the other hand, health of the patient is undermined as he skips essential drugs which doctors would have prescribed according to the health of a patient. Misconceptions that herbal medicines are safe and without side effects need to be addressed. Patients need to be educated regarding health supplements, its consequences, costs and its implications, and nonadherence. The need of the hour is educating patients to be the guardian of their own health. Numerous reviews exist on health supplementation; however, many facts remain unexplored. This review focuses on what needs to be done for optimal health care.
天然的水果和蔬菜,加上健康的饮食,确实能提供身体所需的所有营养。那么,为什么人们要去吃所谓的“保健品”——维生素、矿物质、草药免疫增强剂、益生菌、补品等呢?你真的需要它们吗?印度的病人不顾一切地想要找到通往健康的捷径。他们购买的产品是不必要的,没有任何有益的效果。另一方面,病人的健康受到损害,因为他跳过了医生根据病人的健康状况开出的基本药物。认为草药安全无副作用的误解需要纠正。患者需要被教育关于健康补充,其后果,成本和影响,以及不遵守。当前的需要是教育病人要保护自己的健康。有许多关于保健补充剂的评论;然而,许多事实仍未被探索。本综述的重点是需要做些什么来实现最佳的卫生保健。
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引用次数: 0
Is glucose dysregulation an inflammatory process? 葡萄糖调节异常是炎症过程吗?
Pub Date : 2017-05-01 DOI: 10.4103/2394-2010.208120
Y. Lawal, F. Anumah, A. Bakari
Aim: To determine the relationship between glucose dysregulation and high-sensitive C-reactive protein (hsCRP). Settings and Design: Zaria is a major city located on the high plains of Northern Nigeria, 652.6 m above the sea level, some 950 km away from the coast. Its location is latitude 112°31” N and longitude 7°42” E. This was a cross-sectional observational study. Participants not previously known to have diabetes mellitus (DM) who satisfied the inclusion criteria were enrolled after cluster random sampling. The study was carried out over a period of 12 months. Materials and Methods: Four hundred apparently healthy participants were recruited through cluster sampling from their respective communities after due consent. Relevant biodata were documented, and appropriate examinations including anthropometric measurements were carried out. Plasma glucose and hsCRP levels were subsequently measured. Statistical Analysis Used: Microsoft excel was used for data entry while SPSS software version 19 was used for data analysis. Pearson's Correlation was used to test for association between plasma glucose levels and body mass index (BMI), waist circumference (WC), waist-hip ratio (WHR), and hsCRP. Multiple logistic regression was used to determine whether BMI, WC, WHR, and hsCRP were significant determinants of glucose dysregulation. Significance level was considered P < 0.05. Results and Conclusions: BMI, WC, WHR, and hsCRP were shown to be significant determinants of glucose dysregulation. Therefore, a chronic low-grade inflammation may contribute to the etiopathogenesis of DM.
目的:探讨葡萄糖异常与高敏c反应蛋白(hsCRP)的关系。环境与设计:扎里亚是一个主要城市,位于尼日利亚北部的高平原上,海拔652.6米,距离海岸约950公里。它的位置是北纬112°31”,东经7°42”。这是一个横断面观测研究。以前不知道患有糖尿病(DM)的参与者在整群随机抽样后被纳入。这项研究进行了12个月。材料和方法:经同意后,通过整群抽样从各自社区招募了400名表面健康的参与者。记录了相关的生物数据,并进行了适当的检查,包括人体测量。随后测量血浆葡萄糖和hsCRP水平。统计分析使用:使用Microsoft excel进行数据录入,使用SPSS 19软件进行数据分析。Pearson’s Correlation用于检测血浆葡萄糖水平与体重指数(BMI)、腰围(WC)、腰臀比(WHR)和hsCRP之间的关系。采用多元logistic回归来确定BMI、WC、WHR和hsCRP是否是血糖失调的重要决定因素。P < 0.05为显著性水平。结果和结论:BMI、WC、WHR和hsCRP被证明是葡萄糖失调的重要决定因素。因此,慢性低度炎症可能与糖尿病的发病有关。
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引用次数: 1
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Journal of Health Research and Reviews
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